Transfection efficiency increases by incorporating hydrophobic monomer units into polymeric gene carriers

Journal of Controlled Release

Volumn 68, Issue 1, 2000, Pages 1-8

  Kurisawa, Motoichi ^a   Yokoyama, Masayuki ^a   Okano, Teruo ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Cationic polymers; Gene delivery; Hydrophobic interaction; Plasmid; Transfection

Indexed keywords

BETA GALACTOSIDASE; COPOLYMER; DRUG CARRIER; MONOMER; POLY(N ISOPROPYLACRYLAMIDE); POLYMETHACRYLIC ACID DERIVATIVE;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ELECTROPHORESIS; GENE TARGETING; GENE THERAPY; GENETIC TRANSFECTION; HYDROPHOBICITY; NONHUMAN; PLASMID; PRIORITY JOURNAL; REPORTER GENE;

ANIMALS; COS CELLS; DRUG CARRIERS; GENE THERAPY; LAC OPERON; PLASMIDS; POLYMETHACRYLIC ACIDS; TRANSFECTION;

EID: 0034738843     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(00)00246-7     Document Type: Article

References (40)

1. Marquet M., Horn N.A., Meek J.A. Process development for the manufacture of plasmid DNA vectors for use in gene therapy. Pharm. Technol. 4:1996;28-46.
2. Patnum D., Kopecek J. Polymer conjugates with anticancer activity. Adv. Polym. Sci. 122:1995;55-123.
3. Duncan R., Dimitrijevic S., Evagorou E.G. The role of polymer conjugates in the diagnosis and treatment of cancer. STP Pharm. Sci. 6:1996;237-263.
4. Yokoyama M. Site specific drug delivery using polymeric carriers. Ikoma T. Advances in Polymeric Systems for Drug Delivery. 1994;24-66 Gordon & Breach, Yverdon, Switzerland.
5. Maeda H., Konno T. Metamorphosis of neocarzinostatin to SMANCS: chemistry, biology, pharmacology, and clinical effect of the first prototype anticancer polymer therapeutic. Maeda H., Edo K., Ishida N. Neocarzinostatin the Past, Present and Future of an Anticancer Drug. 1997;227-268 Springer, Tokyo.
6. Duncan R., Seymour L.W., O'Hare K.B., Flanagan P.A., Wedge S., Hume I.C., Ulblich K., Strohalm J., Subr V., Spreafico F., Grandi M., Ripamonti M., Farco M., Surato A. Preclinical evaluation of polymer-bound doxorubicin. J. Control. Release. 19:1992;331-346.
7. Kikuchi A., Okano T. Temperature-responsive polymers as on-off switches for intelligent biointerfaces. Okano T. Biorelated Polymers and Gels. 1998;1-28 Academic Press, San Diego.
8. Yokoyama M. Novel passive targetable drug delivery with polymeric micelles. Okano T. Biorelated Polymers and Gels. 1998;193-230 Academic Press, San Diego.
9. Ulbrich K., Konak C., Tuzar Z., Kopecek J. Solution properties of drug carriers based on poly[N-(2-hydroxylpropyl)methacrylamide] containing biodegradable bonds. Makromol. Chem. 188:1987;1261-1272.
10. Yokoyama M., Okano T., Sakurai Y., Ekimoto H., Shibazaki C., Kataoka K. Toxicity and antitumor activity against solid tumors of micelle-forming polymeric anticancer drug and its extremely long circulation in blood. Cancer Res. 51:1991;3229-3236.
11. Kwon G.S., Suwa S., Yokoyama M., Okano T., Sakurai Y., Kataoka K. Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer-adriamycin conjugates. J. Control. Release. 29:1994;17-23.
12. Yokoyama M., Okano T., Sakurai Y., Fukushima S., Okamoto K., Kataoka K. Selective delivery of adriamycin to a solid tumor using a polymeric micelle carrier system. J. Drug Target. 7:1999;171-186.
13. Thierry A.R., Lunardi-Iskandar Y., Bryant J.L., Rabinovich P., Gallo R.C., Mahan L.C. Synthetic gene delivery: biodistribution and long-term expression of a transgene in mice. Proc. Natl. Acad. Sci. USA. 92:1995;9742-9746.
14. Felgner P., Gadek T.R., Holm M., Roman R., Chan H.W., Wenz M., Northrop J.P., Ringold G.M., Danielsen M. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc. Natl. Acad. Sci. USA. 84:1987;7413-7417.
15. Gao X., Huang L. A novel cationic liposome reagent for efficient transfection of mammalian cells. Biochem. Biophys. Res. Commun. 179:1991;280-285.
16. Boussif O., Lezoualc'h F., Zanta M.A., Mergny M.D., Scherman D., Demeneix B., Behr J.P. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethyleneimine. Proc. Natl. Acad. Sci. USA. 92:1995;7297-7301.
17. Wu G.Y., Wu C.H. Receptor-mediated gene delivery and expression in vivo. J. Biol. Chem. 263:1988;14621-14624.
18. Choi Y.H., Liu F., Kim J.-S., Choi Y.K., Park J.S., Kim S.W. Polyethylene glycol-grafted poly-L-lysine as polymeric gene carrier. J. Control. Release. 54:1998;39-48.
19. Toncheva V., Wolfert M.A., Dash P.R., Oupicky D., Ulbrich K., Seymour L.W., Schacht E.H. Novel vectors for gene delivery formed by self-assembly of DNA with poly(L-lysine) grafted with hydrophilic polymers. Biochim. Biophys. Acta. 1380:1998;354-368.
20. Wetering P.V.D., Cherng J.-Y., Talsma H., Crommelin D.J.A., Hennink W.E. 2-(Dimethylamino)ethyl methacrylate based (co)polymers as gene transfer agent. J. Control. Release. 53:1998;145-153.
21. Sorgi F., Bhattacharya S., Huang L. Protamine sulfate enhances lipid-mediated gene transfer. Gene Ther. 4:1997;961-968.
22. Behr J.P. Gene transfer with synthetic cationic amphiphiles: prospects for gene therapy. Bioconjug. Chem. 5:1994;382-389.
23. Zabner J., Fasbender A.J., Moninger T., Poellinger K.A., Welsh M.J. Cellular and molecular barriers to gene transfer by a cationic lipid. J. Biol. Chem. 270:1995;18997-19007.
24. Tseng W.C., Haselton F.R., Giogio T.D. Transfection by cationic liposomes using simultaneous single cell measurements of plasmid delivery and transgene expression. J. Biol. Chem. 272:1997;25641-25647.
25. Friend D.S., Papahadjopoulos D., Debs R.J. Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes. Biochim. Biophys. Acta. 1278:1996;41-50.
26. Kabanov A.V. Taking polycation gene delivery systems from in vitro to in vivo. Pharm. Sci. Technol. Today. 2:1999;365-372.
27. Yokoyama M., Zhang J., Whitton J.L. DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infection. J. Virol. 69:1995;2684-2688.
28. Lim K., Chae C.B. A simple assay for DNA transfection by incubation of the cells in culture dishes with substrates for beta-galactosidase. BioTechniques. 7:1989;576-579.
29. Heskins M., Guillet J.E. Solution properties of poly(N-isopropylacrylamide). J. Macromol. Sci. Chem. A2:1968;1441-1455.
30. Yoshida R., Uchida K., Kaneko Y., Sakai K., Kikuchi A., Sakurai Y., Okano T. Comb-type grafted hydrogels with rapid de-swelling response to temperature changes. Nature. 374:1995;240-242.
31. Kaneko Y., Sakai K., Kikuchi A., Yoshida R., Sakurai Y., Okano T. Influence of freely mobile grafted chain length on dynamic properties of comb-type grafted poly(N-isopropylacrylamide) hydrogels. Macromolecules. 28:1995;7717-7723.
32. Bae Y.H., Okano T., Kim S.W. A new thermo-sensitive hydrogel: interpenetrating polymer networks from N-acryloylpyrrolidine and poly(ethylene oxide). Makromol. Chem. Rapid Commun. 9:1988;185-189.
33. Matsukata M., Aoki T., Sanui K., Ogata N., Kikuchi A., Sakurai Y., Okano T. Effect of molecular architecture of poly(N-isopropylacrylamide)-trypsin conjugates on their solution and enzymatic properties. Bioconjug. Chem. 7:1996;96-101.
34. Kanazawa H., Yamamoto K., Matsushima Y., Takai N., Kikuchi A., Sakurai Y., Okano T. Temperature responsive chromatography using poly(N-isopropylacrylamide)-modified silica. Anal. Chem. 68:1996;100-105.
35. Kanazawa H., Kashiwase Y., Yamamoto K., Matsushima Y., Takai N., Kikuchi A., Sakurai Y., Okano T. Temperature responsive liquid chromatography. 2. Effect of hydrophobic groups in N-isopropylacrylamide copolymer-modified silica. Anal. Chem. 69:1997;823-830.
36. Yakushiji T., Sakai K., Kikuchi A., Aoyagi T., Sakurai Y., Okano T. Graft architectural effects on thermo-responsive wettability changes of (N-isopropylacrylamide)-modified silica. Langmuir. 14:1998;4657-4662.
37. Wetering P.V.D., Moret E.E., S-Nieuwenbroek N.M.E., Steenbergen M.J.V., Hennink W.E. Structure-activity relationships of water-soluble cationic methacrylate/methacrylamide polymers for nonviral gene delivery. Bioconjug. Chem. 10:1999;589-597.
38. Hinrichs W.L.J., S-Nieuwenbroek N.M.E., Wetering P.V.D., Hennink W.E. Thermosensitive polymers as carriers for DNA delivery. J. Control. Release. 60:1999;249-259.
39. Sato T., Kawakami T., Shirakawa N., Okahata Y. Preparation and characterization of DNA-lipoglutamate complexes. Bull. Chem. Soc. Jpn. 68:1995;2709-2715.
40. Kabavov A.V., Kavanov V.A. DNA complexes with polycations for the delivery of genetic materials into cells. Bioconjug. Chem. 6:1995;7-20.