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Volumn 65, Issue 5, 2015, Pages 963-969

Dr Lewis kitchener dahl, the dahl rats, and the “Inconvenient truth” about the genetics of hypertension

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ART; DAHL RAT; DISEASE MODEL; GENETICS; HISTORY; HUMAN; HYPERTENSION; MEDICAL RESEARCH; RAT; UNITED STATES;

EID: 85027954617     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.114.04368     Document Type: Article
Times cited : (17)

References (111)
  • 1
    • 79953213270 scopus 로고    scopus 로고
    • Renin, genes, and beyond: 40 years of molecular discoveries in the hypertension field
    • Morris BJ. Renin, genes, and beyond: 40 years of molecular discoveries in the hypertension field. Hypertension. 2011;57:538-548. doi: 10.1161/ HYPERTENSIONAHA.110.166967.
    • (2011) Hypertension , vol.57 , pp. 538-548
    • Morris, B.J.1
  • 3
    • 0015288936 scopus 로고
    • Salt and hypertension
    • Dahl LK. Salt and hypertension. Am J Clin Nutr. 1972;25:231-244.
    • (1972) Am J Clin Nutr , vol.25 , pp. 231-244
    • Dahl, L.K.1
  • 4
    • 0019410808 scopus 로고
    • James howard means and his romance with the thyroid gland
    • Harvey AM. James Howard Means and his romance with the thyroid gland. Am J Med. 1981;70:1158-1160.
    • (1981) Am J Med , vol.70 , pp. 1158-1160
    • Harvey, A.M.1
  • 5
  • 7
    • 0014673226 scopus 로고
    • Modification of Parkinsonism-chronic treatment with L-dopa
    • Cotzias GC, Papavasiliou PS, Gellene R. Modification of Parkinsonism-chronic treatment with L-dopa. N Engl J Med. 1969;280:337-345. doi: 10.1056/NEJM196902132800701.
    • (1969) N Engl J Med , vol.280 , pp. 337-345
    • Cotzias, G.C.1    Papavasiliou, P.S.2    Gellene, R.3
  • 8
    • 0014413441 scopus 로고
    • L-DOPA for parkinsonism
    • Cotzias GC. L-Dopa for Parkinsonism. N Engl J Med. 1968;278:630.
    • (1968) N Engl J Med , vol.278 , pp. 630
    • Cotzias, G.C.1
  • 9
    • 0014260608 scopus 로고
    • Experimental treatment of parkinsonism with L-Dopa
    • Cotzias GC, Papavasiliou PS, Gellene R. Experimental treatment of parkinsonism with L-Dopa. Neurology. 1968;18:276-277.
    • (1968) Neurology , vol.18 , pp. 276-277
    • Cotzias, G.C.1    Papavasiliou, P.S.2    Gellene, R.3
  • 10
    • 0002951673 scopus 로고
    • Possible role of salt intake in the development of essential hypertension
    • Cottier PB, Bock KD, ed. Berlin: Springer; Reprinted in: Int J Epidemiol. 2005;34:967-972
    • Dahl LK. Possible role of salt intake in the development of essential hypertension. In: Cottier PB, Bock KD, ed. Essential Hypertension, an International Symposium. Berlin: Springer; 1960:53-65; Reprinted in: Int J Epidemiol. 2005;34:967-972.
    • (1960) Essential Hypertension, an International Symposium , pp. 53-65
    • Dahl, L.K.1
  • 11
    • 0014766201 scopus 로고
    • Hypertension and death from consumption of processed baby foods by rats
    • Dahl LK, Heine M, Leitl G, Tassinari L. Hypertension and death from consumption of processed baby foods by rats. Proc Soc Exp Biol Med. 1970;133:1405-1408.
    • (1970) Proc Soc Exp Biol Med , vol.133 , pp. 1405-1408
    • Dahl, L.K.1    Heine, M.2    Leitl, G.3    Tassinari, L.4
  • 12
    • 0014687398 scopus 로고
    • Salt and blood pressure
    • Dahl LK. Salt and blood pressure. Lancet. 1969;1:622-623.
    • (1969) Lancet , vol.1 , pp. 622-623
    • Dahl, L.K.1
  • 14
    • 0014316810 scopus 로고
    • Salt in processed baby foods
    • Dahl LK. Salt in processed baby foods. Am J Clin Nutr. 1968;21:787-792.
    • (1968) Am J Clin Nutr , vol.21 , pp. 787-792
    • Dahl, L.K.1
  • 15
    • 0014277797 scopus 로고
    • Letters to the editor: Salt in the infant's diet
    • Dahl LK. Letters to the editor: salt in the infant's diet. Nutr Rev. 1968;26:124-125.
    • (1968) Nutr Rev , vol.26 , pp. 124-125
    • Dahl, L.K.1
  • 16
    • 0013448126 scopus 로고
    • Effects of chronic excess salt ingestion. Role of genetic factors in both doca-salt and renal hypertension
    • Dahl LK, Heine M, Tassinari L. Effects of chronic excess salt ingestion. Role of genetic factors in both doca-salt and renal hypertension. J Exp Med. 1963;118:605-617.
    • (1963) J Exp Med , vol.118 , pp. 605-617
    • Dahl, L.K.1    Heine, M.2    Tassinari, L.3
  • 17
    • 0000770425 scopus 로고
    • Effects of chronic excess salt ingestion: Experimental hypertension in the rat
    • Dahl LK, Schackow E. Effects of chronic excess salt ingestion: experimental hypertension in the rat. Can Med Assoc J. 1964;90:155-160.
    • (1964) Can Med Assoc J , vol.90 , pp. 155-160
    • Dahl, L.K.1    Schackow, E.2
  • 18
    • 75449133820 scopus 로고
    • Chronic excess salt consumption as an etiologic factor in human hypertension
    • Dahl LK. Chronic excess salt consumption as an etiologic factor in human hypertension. Heart Bull. 1963;11:61-65.
    • (1963) Heart Bull , vol.11 , pp. 61-65
    • Dahl, L.K.1
  • 19
    • 15844392489 scopus 로고
    • Metabolic aspects of hypertension
    • Dahl LK. Metabolic aspects of hypertension. Annu Rev Med. 1963;14:69-98. doi: 10.1146/annurev.me.14.020163.000441.
    • (1963) Annu Rev Med , vol.14 , pp. 69-98
    • Dahl, L.K.1
  • 20
    • 27544514082 scopus 로고
    • Salt intake, adrenocortical function and hypertension
    • Dahl LK. Salt intake, adrenocortical function and hypertension. Nature. 1958;181:989-990.
    • (1958) Nature , vol.181 , pp. 989-990
    • Dahl, L.K.1
  • 21
    • 27544444192 scopus 로고
    • Salt, fat and hypertension: The Japanese experience
    • Dahl LK. Salt, fat and hypertension: the Japanese experience. Nutr Rev. 1960;18:97-99.
    • (1960) Nutr Rev , vol.18 , pp. 97-99
    • Dahl, L.K.1
  • 23
    • 0040409707 scopus 로고
    • Sodium intake of the American Male: Implications on the etiology of essential hypertension
    • Dahl LK. Sodium intake of the American male: implications on the etiology of essential hypertension. Am J Clin Nutr. 1958;6:1-7.
    • (1958) Am J Clin Nutr , vol.6 , pp. 1-7
    • Dahl, L.K.1
  • 24
    • 70449226729 scopus 로고
    • Salt intake and salt need
    • concl.
    • Dahl LK. Salt intake and salt need. N Engl J Med. 1958;258:1205-1208 concl. doi: 10.1056/NEJM195806122582406.
    • (1958) N Engl J Med , vol.258 , pp. 1205-1208
    • Dahl, L.K.1
  • 25
    • 27544466474 scopus 로고
    • Role of dietary sodium in essential hypertension
    • Dahl LK. Role of dietary sodium in essential hypertension. J Am Diet Assoc. 1958;34:585-590.
    • (1958) J Am Diet Assoc , vol.34 , pp. 585-590
    • Dahl, L.K.1
  • 26
    • 84933416556 scopus 로고
    • Studies on the role of salt and genetics in hypertension
    • Dahl LK. Studies on the role of salt and genetics in hypertension. Acad Med N J Bull. 1964;10:269-279.
    • (1964) Acad Med N J Bull , vol.10 , pp. 269-279
    • Dahl, L.K.1
  • 27
    • 35548936549 scopus 로고
    • Dietary treatment of hypertension. III. The effect of protein on appetite and weight]
    • Dole VP, Dahl LK, Schwartz IL, Cotzias GC, Thaysen JH, Harris C. [Dietary treatment of hypertension. III. The effect of protein on appetite and weight]. J Clin Invest. 1953;32:185-191. doi: 10.1172/JCI102726.
    • (1953) J Clin Invest , vol.32 , pp. 185-191
    • Dole, V.P.1    Dahl, L.K.2    Schwartz, I.L.3    Cotzias, G.C.4    Thaysen, J.H.5    Harris, C.6
  • 28
    • 9244260240 scopus 로고
    • Dietary treatment of hypertension. II. Sodium depletion as related to the therapeutic effect
    • Dole VP, Dahl LK, Cotzias GC, Dziewiatkowski DD, Harris C. Dietary treatment of hypertension. II. Sodium depletion as related to the therapeutic effect. J Clin Invest. 1951;30:584-595. doi: 10.1172/JCI102476.
    • (1951) J Clin Invest , vol.30 , pp. 584-595
    • Dole, V.P.1    Dahl, L.K.2    Cotzias, G.C.3    Dziewiatkowski, D.D.4    Harris, C.5
  • 29
    • 1842355607 scopus 로고
    • Dietary treatment of hypertension; clinical and metabolic studies of patients on the rice-fruit diet
    • Dole VP, Dahl LK, Cotzias GC, Eder HA, Krebs ME. Dietary treatment of hypertension; clinical and metabolic studies of patients on the rice-fruit diet. J Clin Invest. 1950;29:1189-1206. doi: 10.1172/JCI102357.
    • (1950) J Clin Invest , vol.29 , pp. 1189-1206
    • Dole, V.P.1    Dahl, L.K.2    Cotzias, G.C.3    Eder, H.A.4    Krebs, M.E.5
  • 30
    • 0014883138 scopus 로고
    • Effects of chronic excess salt ingestion. Inheritance of hypertension in the rat
    • Knudsen KD, Dahl LK, Thompson K, Iwai J, Heine M, Leitl G. Effects of chronic excess salt ingestion. Inheritance of hypertension in the rat. J Exp Med. 1970;132:976-1000.
    • (1970) J Exp Med , vol.132 , pp. 976-1000
    • Knudsen, K.D.1    Dahl, L.K.2    Thompson, K.3    Iwai, J.4    Heine, M.5    Leitl, G.6
  • 31
    • 0014820090 scopus 로고
    • Effects of chronic excess salt ingestion. Morphologic findings in kidneys of rats with differing genetic susceptibilities to hypertension
    • Jaffé D, Sutherland LE, Barker DM, Dahl LK. Effects of chronic excess salt ingestion. Morphologic findings in kidneys of rats with differing genetic susceptibilities to hypertension. Arch Pathol. 1970;90:1-16.
    • (1970) Arch Pathol , vol.90 , pp. 1-16
    • Jaffé, D.1    Sutherland, L.E.2    Barker, D.M.3    Dahl, L.K.4
  • 32
    • 0014747650 scopus 로고
    • Effects of chronic excess salt ingestion. Juxtaglomerular granulation in kidneys of rats with differing genetic susceptibilities to hypertension
    • Barker DM, Sutherland LE, Jaffé D, Dahl LD. Effects of chronic excess salt ingestion. Juxtaglomerular granulation in kidneys of rats with differing genetic susceptibilities to hypertension. Arch Pathol. 1970;89:247-258.
    • (1970) Arch Pathol , vol.89 , pp. 247-258
    • Barker, D.M.1    Sutherland, L.E.2    Jaffé, D.3    Dahl, L.D.4
  • 33
    • 0014237796 scopus 로고
    • Effects of chronic excess salt ingestion. Modification of experimental hypertension in the rat by variations in the diet
    • Dahl LK, Knudsen KD, Heine MA, Leitl GJ. Effects of chronic excess salt ingestion. Modification of experimental hypertension in the rat by variations in the diet. Circ Res. 1968;22:11-18.
    • (1968) Circ Res , vol.22 , pp. 11-18
    • Dahl, L.K.1    Knudsen, K.D.2    Heine, M.A.3    Leitl, G.J.4
  • 34
    • 0014137903 scopus 로고
    • Effects of chronic excess salt ingestion. Genetic influence on the development of salt hypertension in parabiotic rats: Evidence for a humoral factor
    • Dahl LK, Knudsen KD, Heine M, Leitl G. Effects of chronic excess salt ingestion. Genetic influence on the development of salt hypertension in parabiotic rats: evidence for a humoral factor. J Exp Med. 1967;126:687-699.
    • (1967) J Exp Med , vol.126 , pp. 687-699
    • Dahl, L.K.1    Knudsen, K.D.2    Heine, M.3    Leitl, G.4
  • 35
    • 0013940867 scopus 로고
    • Effects of chronic excess salt ingestion: Lack of gross salt retention in salt-hypertension
    • Schackow E, Dahl LK. Effects of chronic excess salt ingestion: lack of gross salt retention in salt-hypertension. Proc Soc Exp Biol Med. 1966;122:952-957.
    • (1966) Proc Soc Exp Biol Med , vol.122 , pp. 952-957
    • Schackow, E.1    Dahl, L.K.2
  • 36
    • 0013802590 scopus 로고
    • Effects of chronic excess salt ingestion. Further demonstration that genetic factors influence the development of hypertension: Evidence from experimental hypertension due to cortisone and to adrenal regeneration
    • Dahl LK, Heine M, Tassinari L. Effects of chronic excess salt ingestion. Further demonstration that genetic factors influence the development of hypertension: evidence from experimental hypertension due to cortisone and to adrenal regeneration. J Exp Med. 1965;122:533-545.
    • (1965) J Exp Med , vol.122 , pp. 533-545
    • Dahl, L.K.1    Heine, M.2    Tassinari, L.3
  • 37
    • 0007625529 scopus 로고
    • Effects of chronic excess salt ingestion. Vascular reactivity in two strains of rats with opposite genetic susceptibility to experimental hypertension
    • Dahl LK, Heine M, Tassinari L. Effects of chronic excess salt ingestion. Vascular reactivity in two strains of rats with opposite genetic susceptibility to experimental hypertension. Circulation. 1964;30:Suppl 2:11-Suppl 2:22.
    • (1964) Circulation , vol.30 , pp. 211-222
    • Dahl, L.K.1    Heine, M.2    Tassinari, L.3
  • 38
    • 0000938436 scopus 로고
    • Effects of chronia excess salt ingestion. Evidence that genetic factors play an important role in susceptibility to experimental hypertension
    • Dahl LK, Heine M, Tassinari L. Effects of chronia excess salt ingestion. Evidence that genetic factors play an important role in susceptibility to experimental hypertension. J Exp Med. 1962;115:1173-1190.
    • (1962) J Exp Med , vol.115 , pp. 1173-1190
    • Dahl, L.K.1    Heine, M.2    Tassinari, L.3
  • 39
    • 0016733244 scopus 로고
    • Primary role of renal homografts in setting chronic blood pressure levels in rats
    • Dahl LK, Heine M. Primary role of renal homografts in setting chronic blood pressure levels in rats. Circ Res. 1975;36:692-696.
    • (1975) Circ Res , vol.36 , pp. 692-696
    • Dahl, L.K.1    Heine, M.2
  • 40
    • 0017249629 scopus 로고
    • Mutant forms of cytochrome P-450 controlling both 18- And 11beta-steroid hydroxylation in the rat
    • Rapp JP, Dahl LK. Mutant forms of cytochrome P-450 controlling both 18- and 11beta-steroid hydroxylation in the rat. Biochemistry. 1976;15:1235-1242.
    • (1976) Biochemistry , vol.15 , pp. 1235-1242
    • Rapp, J.P.1    Dahl, L.K.2
  • 41
    • 17144445419 scopus 로고
    • Genetic control of blood pressure and corticosteroid production in rats
    • Rapp JP, Knudsen KD, Iwai J, Dahl LK. Genetic control of blood pressure and corticosteroid production in rats. Circ Res. 1973;32:Suppl 1:139-Suppl 1:149.
    • (1973) Circ Res , vol.32 , pp. 1139-1149
    • Rapp, J.P.1    Knudsen, K.D.2    Iwai, J.3    Dahl, L.K.4
  • 42
    • 0015605297 scopus 로고
    • Suppression of aldosterone in salt susceptible and salt resistant rats
    • Rapp JP, Dahl LK. Suppression of aldosterone in salt susceptible and salt resistant rats. Endocrinology. 1973;92:1286-1289. doi: 10.1210/ endo-92-4-1286.
    • (1973) Endocrinology , vol.92 , pp. 1286-1289
    • Rapp, J.P.1    Dahl, L.K.2
  • 43
    • 0015499123 scopus 로고
    • Possible role of 18-hydroxy-deoxycorticosterone in hypertension
    • Rapp JP, Dahl LK. Possible role of 18-hydroxy-deoxycorticosterone in hypertension. Nature. 1972;237:338-339.
    • (1972) Nature , vol.237 , pp. 338-339
    • Rapp, J.P.1    Dahl, L.K.2
  • 44
    • 0015350309 scopus 로고
    • Mendelian inheritance of 18- And ll beta-steroid hydroxylase activities in the adrenals of rats genetically susceptible or resistant to hypertension
    • Rapp JP, Dahl LK. Mendelian inheritance of 18- and ll beta-steroid hydroxylase activities in the adrenals of rats genetically susceptible or resistant to hypertension. Endocrinology. 1972;90:1435-1446. doi: 10.1210/endo-90-6-1435.
    • (1972) Endocrinology , vol.90 , pp. 1435-1446
    • Rapp, J.P.1    Dahl, L.K.2
  • 45
    • 0015060760 scopus 로고
    • 18-Hydrox-deoxycorticosterone secretion in experimental hypertension in rats
    • Rapp JP, Dahl LK. 18-Hydrox-deoxycorticosterone secretion in experimental hypertension in rats. Circ Res. 1971;28:Suppl 2:153-Suppl 2:159.
    • (1971) Circ Res , vol.28 , pp. 2153-2159
    • Rapp, J.P.1    Dahl, L.K.2
  • 46
    • 0014984689 scopus 로고
    • Adrenal steroidogenesis in rats bred for susceptibility and resistance to the hypertensive effect of salt
    • Rapp JP, Dahl LK. Adrenal steroidogenesis in rats bred for susceptibility and resistance to the hypertensive effect of salt. Endocrinology. 1971;88:52-65. doi: 10.1210/endo-88-1-52.
    • (1971) Endocrinology , vol.88 , pp. 52-65
    • Rapp, J.P.1    Dahl, L.K.2
  • 47
    • 0021858418 scopus 로고
    • Development and characteristics of inbred strains of Dahl salt-sensitive and salt-resistant rats
    • Rapp JP and Dene H. Development and characteristics of inbred strains of Dahl salt-sensitive and salt-resistant rats. Hypertension. 1985;7:340-349.
    • (1985) Hypertension , vol.7 , pp. 340-349
    • Rapp, J.P.1    Dene, H.2
  • 48
    • 0033979807 scopus 로고    scopus 로고
    • Genetic analysis of inherited hypertension in the rat
    • Rapp JP. Genetic analysis of inherited hypertension in the rat. Physiol Rev. 2000;80:135-172.
    • (2000) Physiol Rev , vol.80 , pp. 135-172
    • Rapp, J.P.1
  • 54
    • 84861128135 scopus 로고    scopus 로고
    • Role of 20-HETE in the antihypertensive effect of transfer of chromosome 5 from Brown Norway to Dahl salt-sensitive rats
    • Williams JM, Fan F, Murphy S, Schreck C, Lazar J, Jacob HJ, Roman RJ. Role of 20-HETE in the antihypertensive effect of transfer of chromosome 5 from Brown Norway to Dahl salt-sensitive rats. Am J Physiol Regul Integr Comp Physiol. 2012;302:R1209-R1218. doi: 10.1152/ ajpregu.00604.2011.
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.302 , pp. R1209-R1218
    • Williams, J.M.1    Fan, F.2    Murphy, S.3    Schreck, C.4    Lazar, J.5    Jacob, H.J.6    Roman, R.J.7
  • 55
    • 3843052401 scopus 로고    scopus 로고
    • Dissecting quantitative trait loci into opposite blood pressure effects on Dahl rat chromosome 8 by congenic strains
    • Ariyarajah A, Palijan A, Dutil J, Prithiviraj K, Deng Y, Deng AY. Dissecting quantitative trait loci into opposite blood pressure effects on Dahl rat chromosome 8 by congenic strains. J Hypertens. 2004;22:1495-1502.
    • (2004) J Hypertens , vol.22 , pp. 1495-1502
    • Ariyarajah, A.1    Palijan, A.2    Dutil, J.3    Prithiviraj, K.4    Deng, Y.5    Deng, A.Y.6
  • 56
    • 31944435692 scopus 로고    scopus 로고
    • Epistasis, not numbers, regulates functions of clustered Dahl rat quantitative trait loci applicable to human hypertension
    • Charron S, Duong C, Ménard A, Roy J, Eliopoulos V, Lambert R, Deng AY. Epistasis, not numbers, regulates functions of clustered Dahl rat quantitative trait loci applicable to human hypertension. Hypertension. 2005;46:1300-1308. doi: 10.1161/01.HYP.0000192024.72367.c3.
    • (2005) Hypertension , vol.46 , pp. 1300-1308
    • Charron, S.1    Duong, C.2    Ménard, A.3    Roy, J.4    Eliopoulos, V.5    Lambert, R.6    Deng, A.Y.7
  • 57
    • 29644436113 scopus 로고    scopus 로고
    • A loss of genome buffering capacity of Dahl salt-sensitive model to modulate blood pressure as a cause of hypertension
    • Charron S, Lambert R, Eliopoulos V, Duong C, Ménard A, Roy J, Deng AY. A loss of genome buffering capacity of Dahl salt-sensitive model to modulate blood pressure as a cause of hypertension. Hum Mol Genet. 2005;14:3877-3884. doi: 10.1093/hmg/ddi412.
    • (2005) Hum Mol Genet , vol.14 , pp. 3877-3884
    • Charron, S.1    Lambert, R.2    Eliopoulos, V.3    Duong, C.4    Ménard, A.5    Roy, J.6    Deng, A.Y.7
  • 58
    • 42049114663 scopus 로고    scopus 로고
    • Submegabase resolution of epistatically interacting quantitative trait loci for blood pressure applicable for essential hypertension
    • Chauvet C, Charron S, Ménard A, Xiao C, Roy J, Deng AY. Submegabase resolution of epistatically interacting quantitative trait loci for blood pressure applicable for essential hypertension. J Hypertens. 2008;26:893-901. doi: 10.1097/HJH.0b013e3282f85ded.
    • (2008) J Hypertens , vol.26 , pp. 893-901
    • Chauvet, C.1    Charron, S.2    Ménard, A.3    Xiao, C.4    Roy, J.5    Deng, A.Y.6
  • 59
    • 84887012469 scopus 로고    scopus 로고
    • Modularization and epistatic hierarchy determine homeostatic actions of multiple blood pressure quantitative trait loci
    • Chauvet C, Crespo K, Ménard A, Roy J, Deng AY. Modularization and epistatic hierarchy determine homeostatic actions of multiple blood pressure quantitative trait loci. Hum Mol Genet. 2013;22:4451-4459. doi: 10.1093/hmg/ddt294.
    • (2013) Hum Mol Genet , vol.22 , pp. 4451-4459
    • Chauvet, C.1    Crespo, K.2    Ménard, A.3    Roy, J.4    Deng, A.Y.5
  • 60
    • 79958767623 scopus 로고    scopus 로고
    • Α-Kinase 2 is a novel candidate gene for inherited hypertension in Dahl rats
    • Chauvet C, Crespo K, Ménard A, Wu Y, Xiao C, Blain M, Roy J, Deng AY. α-Kinase 2 is a novel candidate gene for inherited hypertension in Dahl rats. J Hypertens. 2011;29:1320-1326. doi: 10.1097/ HJH.0b013e32834705e4.
    • (2011) J Hypertens , vol.29 , pp. 1320-1326
    • Chauvet, C.1    Crespo, K.2    Ménard, A.3    Wu, Y.4    Xiao, C.5    Blain, M.6    Roy, J.7    Deng, A.Y.8
  • 64
    • 79951678251 scopus 로고    scopus 로고
    • Normotension in Lewis and Dahl salt-resistant rats is governed by different genes
    • Crespo K, Chauvet C, Blain M, Ménard A, Roy J, Deng AY. Normotension in Lewis and Dahl salt-resistant rats is governed by different genes. J Hypertens. 2011;29:460-465. doi: 10.1097/HJH.0b013e328341f1cc.
    • (2011) J Hypertens , vol.29 , pp. 460-465
    • Crespo, K.1    Chauvet, C.2    Blain, M.3    Ménard, A.4    Roy, J.5    Deng, A.Y.6
  • 65
    • 77953223380 scopus 로고    scopus 로고
    • Identifying physiological origins of baroreflex dysfunction in salt-sensitive hypertension in the Dahl SS rat
    • Bugenhagen SM, Cowley AW Jr, Beard DA. Identifying physiological origins of baroreflex dysfunction in salt-sensitive hypertension in the Dahl SS rat. Physiol Genomics. 2010;42:23-41. doi: 10.1152/ physiolgenomics.00027.2010.
    • (2010) Physiol Genomics , vol.42 , pp. 23-41
    • Bugenhagen, S.M.1    Cowley, A.W.2    Beard, D.A.3
  • 66
    • 1842294593 scopus 로고    scopus 로고
    • Genetic and nongenetic determinants of salt sensitivity and blood pressure
    • Cowley AW, Jr. Genetic and Nongenetic Determinants of Salt Sensitivity and Blood Pressure. Am J Clin Nutr. 1997;65:587S-593S.
    • (1997) Am J Clin Nutr , vol.65 , pp. 587S-593S
    • Cowley, A.W.1
  • 68
    • 84863012892 scopus 로고    scopus 로고
    • Increased expression of NAD(P)H oxidase subunit p67(phox) in the renal medulla contributes to excess oxidative stress and salt-sensitive hypertension
    • Feng D, Yang C, Geurts AM, Kurth T, Liang M, Lazar J, Mattson DL, O'Connor PM, Cowley AW Jr. Increased expression of NAD(P)H oxidase subunit p67(phox) in the renal medulla contributes to excess oxidative stress and salt-sensitive hypertension. Cell Metab. 2012;15:201-208. doi: 10.1016/j.cmet.2012.01.003.
    • (2012) Cell Metab , vol.15 , pp. 201-208
    • Feng, D.1    Yang, C.2    Geurts, A.M.3    Kurth, T.4    Liang, M.5    Lazar, J.6    Mattson, D.L.7    O'Connor, P.M.8    Cowley, A.W.9
  • 70
    • 0141482413 scopus 로고    scopus 로고
    • Insights into Dahl salt-sensitive hypertension revealed by temporal patterns of renal medullary gene expression
    • Liang M, Yuan B, Rute E, Greene AS, Olivier M, Cowley AW Jr. Insights into Dahl salt-sensitive hypertension revealed by temporal patterns of renal medullary gene expression. Physiol Genomics. 2003;12:229-237. doi: 10.1152/physiolgenomics.00089.2002.
    • (2003) Physiol Genomics , vol.12 , pp. 229-237
    • Liang, M.1    Yuan, B.2    Rute, E.3    Greene, A.S.4    Olivier, M.5    Cowley, A.W.6
  • 71
    • 0034923632 scopus 로고    scopus 로고
    • Kidney-specific chromosome transfer in genetic hypertension: The Dahl hypothesis revisited
    • Churchill PC, Churchill MC, Bidani AK, Kurtz TW. Kidney-specific chromosome transfer in genetic hypertension: the Dahl hypothesis revisited. Kidney Int. 2001;60:705-714. doi: 10.1046/j.1523-1755.2001.060002705.x.
    • (2001) Kidney Int , vol.60 , pp. 705-714
    • Churchill, P.C.1    Churchill, M.C.2    Bidani, A.K.3    Kurtz, T.W.4
  • 72
    • 0029582772 scopus 로고
    • Mapping and sequence analysis of the gene encoding the beta subunit of the epithelial sodium channel in experimental models of hypertension
    • Huang H, Pravenec M, Wang JM, Kren V, St Lezin E, Szpirer C, Szpirer J, Kurtz TW. Mapping and sequence analysis of the gene encoding the beta subunit of the epithelial sodium channel in experimental models of hypertension. J Hypertens. 1995;13:1247-1251.
    • (1995) J Hypertens , vol.13 , pp. 1247-1251
    • Huang, H.1    Pravenec, M.2    Wang, J.M.3    Kren, V.4    St Lezin, E.5    Szpirer, C.6    Szpirer, J.7    Kurtz, T.W.8
  • 73
    • 84923342198 scopus 로고    scopus 로고
    • Characteristics of Long Non-coding RNAs in the Brown Norway Rat and Alterations in the Dahl Salt-Sensitive Rat
    • Wang F, Li L, Xu H, Liu Y, Yang C, Cowley AW Jr, Wang N, Liu P, Liang M. Characteristics of Long Non-coding RNAs in the Brown Norway Rat and Alterations in the Dahl Salt-Sensitive Rat. Sci Rep. 2014;4:7146. doi: 10.1038/srep07146.
    • (2014) Sci Rep , vol.4 , pp. 7146
    • Wang, F.1    Li, L.2    Xu, H.3    Liu, Y.4    Yang, C.5    Cowley, A.W.6    Wang, N.7    Liu, P.8    Liang, M.9
  • 74
    • 84897061863 scopus 로고    scopus 로고
    • Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: Effect of salt and genomic sequence
    • Liu Y, Liu P, Yang C, Cowley AW Jr, Liang M. Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequence. Hypertension. 2014;63:827-838. doi: 10.1161/HYPERTENSIONAHA.113.02637.
    • (2014) Hypertension , vol.63 , pp. 827-838
    • Liu, Y.1    Liu, P.2    Yang, C.3    Cowley, A.W.4    Liang, M.5
  • 75
    • 35548972551 scopus 로고    scopus 로고
    • Multiple blood pressure loci on rat chromosome 13 attenuate development of hypertension in the Dahl S hypertensive rat
    • Moreno C, Kaldunski ML, Wang T, Roman RJ, Greene AS, Lazar J, Jacob HJ, Cowley AW Jr. Multiple blood pressure loci on rat chromosome 13 attenuate development of hypertension in the Dahl S hypertensive rat. Physiol Genomics. 2007;31:228-235. doi: 10.1152/ physiolgenomics.00280.2006.
    • (2007) Physiol Genomics , vol.31 , pp. 228-235
    • Moreno, C.1    Kaldunski, M.L.2    Wang, T.3    Roman, R.J.4    Greene, A.S.5    Lazar, J.6    Jacob, H.J.7    Cowley, A.W.8
  • 79
    • 0346294232 scopus 로고    scopus 로고
    • Application of chromosomal substitution techniques in gene-function discovery
    • Cowley AW Jr, Roman RJ, Jacob HJ. Application of chromosomal substitution techniques in gene-function discovery. J Physiol. 2004;554(Pt 1):46-55. doi: 10.1113/jphysiol.2003.052613.
    • (2004) J Physiol , vol.554 , pp. 46-55
    • Cowley, A.W.1    Roman, R.J.2    Jacob, H.J.3
  • 82
    • 0032813954 scopus 로고    scopus 로고
    • Complete genome searches for quantitative trait loci controlling blood pressure and related traits in four segregating populations derived from Dahl hypertensive rats
    • Kato N, Hyne G, Bihoreau MT, Gauguier D, Lathrop GM, Rapp JP. Complete genome searches for quantitative trait loci controlling blood pressure and related traits in four segregating populations derived from Dahl hypertensive rats. Mamm Genome. 1999;10:259-265.
    • (1999) Mamm Genome , vol.10 , pp. 259-265
    • Kato, N.1    Hyne, G.2    Bihoreau, M.T.3    Gauguier, D.4    Lathrop, G.M.5    Rapp, J.P.6
  • 84
    • 0036915587 scopus 로고    scopus 로고
    • Identification of blood pressure quantitative trait loci that differentiate two hypertensive strains
    • Garrett MR, Joe B, Dene H, Rapp JP. Identification of blood pressure quantitative trait loci that differentiate two hypertensive strains. J Hypertens. 2002;20:2399-2406. doi: 10.1097/01.hjh.0000042899.83309.43.
    • (2002) J Hypertens , vol.20 , pp. 2399-2406
    • Garrett, M.R.1    Joe, B.2    Dene, H.3    Rapp, J.P.4
  • 85
    • 0037385533 scopus 로고    scopus 로고
    • Defining the blood pressure QTL on chromosome 7 in Dahl rats by a 177-kb congenic segment containing Cyp11b1
    • Garrett MR, Rapp JP. Defining the blood pressure QTL on chromosome 7 in Dahl rats by a 177-kb congenic segment containing Cyp11b1. Mamm Genome. 2003;14:268-273. doi: 10.1007/s00335-002-2245-9.
    • (2003) Mamm Genome , vol.14 , pp. 268-273
    • Garrett, M.R.1    Rapp, J.P.2
  • 86
    • 67650718354 scopus 로고    scopus 로고
    • Positional identification of variants of Adamts16 linked to inherited hypertension
    • Joe B, Saad Y, Dhindaw S, et al. Positional identification of variants of Adamts16 linked to inherited hypertension. Hum Mol Genet. 2009;18:2825-2838. doi: 10.1093/hmg/ddp218.
    • (2009) Hum Mol Genet , vol.18 , pp. 2825-2838
    • Joe, B.1    Saad, Y.2    Dhindaw, S.3
  • 89
    • 35848934995 scopus 로고    scopus 로고
    • Congenic interval mapping of RNO10 reveals a complex cluster of closely-linked genetic determinants of blood pressure
    • Saad Y,Yerga-Woolwine S, Saikumar J, Farms P, Manickavasagam E, Toland EJ, Joe B. Congenic interval mapping of RNO10 reveals a complex cluster of closely-linked genetic determinants of blood pressure. Hypertension. 2007;50:891-898. doi: 10.1161/HYPERTENSIONAHA.107.097105.
    • (2007) Hypertension , vol.50 , pp. 891-898
    • Saad, Y.1    Yerga-Woolwine, S.2    Saikumar, J.3    Farms, P.4    Manickavasagam, E.5    Toland, E.J.6    Joe, B.7
  • 90
    • 82955195074 scopus 로고    scopus 로고
    • Refined mapping of blood pressure quantitative trait loci using congenic strains developed from two genetically hypertensive rat models
    • Kumarasamy S, Gopalakrishnan K, Toland EJ, Yerga-Woolwine S, Farms P, Morgan EE, Joe B. Refined mapping of blood pressure quantitative trait loci using congenic strains developed from two genetically hypertensive rat models. Hypertens Res. 2011;34:1263-1270. doi: 10.1038/hr.2011.116.
    • (2011) Hypertens Res , vol.34 , pp. 1263-1270
    • Kumarasamy, S.1    Gopalakrishnan, K.2    Toland, E.J.3    Yerga-Woolwine, S.4    Farms, P.5    Morgan, E.E.6    Joe, B.7
  • 91
    • 84920540903 scopus 로고    scopus 로고
    • Multiple blood pressure loci with opposing blood pressure effects on rat chromosome 1 in a homologous region linked to hypertension on human chromosome 15
    • Mell B, Abdul-Majeed S, Kumarasamy S, Waghulde H, Pillai R, Nie Y and Joe B. Multiple blood pressure loci with opposing blood pressure effects on rat chromosome 1 in a homologous region linked to hypertension on human chromosome 15. Hypertens Res. 2014; doi: 10.1038/hr.2014.134.
    • (2014) Hypertens Res
    • Mell, B.1    Abdul-Majeed, S.2    Kumarasamy, S.3    Waghulde, H.4    Pillai, R.5    Nie, Y.6    Joe, B.7
  • 94
    • 56049106350 scopus 로고    scopus 로고
    • Blood pressure and proteinuria effects of multiple quantitative trait loci on rat chromosome 9 that differentiate the spontaneously hypertensive rat from the Dahl salt-sensitive rat
    • Toland EJ, Yerga-Woolwine S, Farms P, Cicila GT, Saad Y, Joe B. Blood pressure and proteinuria effects of multiple quantitative trait loci on rat chromosome 9 that differentiate the spontaneously hypertensive rat from the Dahl salt-sensitive rat. J Hypertens. 2008;26:2134-2141. doi: 10.1097/HJH.0b013e32830ef95c.
    • (2008) J Hypertens , vol.26 , pp. 2134-2141
    • Toland, E.J.1    Yerga-Woolwine, S.2    Farms, P.3    Cicila, G.T.4    Saad, Y.5    Joe, B.6
  • 95
    • 0036134391 scopus 로고    scopus 로고
    • Multiple blood pressure QTL on rat chromosome 2 defined by congenic Dahl rats
    • Garrett MR, Rapp JP. Multiple blood pressure QTL on rat chromosome 2 defined by congenic Dahl rats. Mamm Genome. 2002;13:41-44.
    • (2002) Mamm Genome , vol.13 , pp. 41-44
    • Garrett, M.R.1    Rapp, J.P.2
  • 97
    • 33845750086 scopus 로고    scopus 로고
    • Substitution mapping in dahl rats identifies two distinct blood pressure quantitative trait loci within 1.12- And 1.25-mb intervals on chromosome 3
    • Lee SJ, Liu J, Westcott AM, Vieth JA, DeRaedt SJ, Yang S, Joe B, Cicila GT. Substitution mapping in dahl rats identifies two distinct blood pressure quantitative trait loci within 1.12- and 1.25-mb intervals on chromosome 3. Genetics. 2006;174:2203-2213. doi: 10.1534/genetics.106.061747.
    • (2006) Genetics , vol.174 , pp. 2203-2213
    • Lee, S.J.1    Liu, J.2    Westcott, A.M.3    Vieth, J.A.4    DeRaedt, S.J.5    Yang, S.6    Joe, B.7    Cicila, G.T.8
  • 98
    • 0035865015 scopus 로고    scopus 로고
    • High-resolution mapping of the blood pressure QTL on chromosome 7 using Dahl rat congenic strains
    • Cicila GT, Garrett MR, Lee SJ, Liu J, Dene H, Rapp JP. High-resolution mapping of the blood pressure QTL on chromosome 7 using Dahl rat congenic strains. Genomics. 2001;72:51-60. doi: 10.1006/geno.2000.6442.
    • (2001) Genomics , vol.72 , pp. 51-60
    • Cicila, G.T.1    Garrett, M.R.2    Lee, S.J.3    Liu, J.4    Dene, H.5    Rapp, J.P.6
  • 99
    • 1542270222 scopus 로고    scopus 로고
    • Substitution mapping of a blood pressure quantitative trait locus to a 2.73 Mb region on rat chromosome 1
    • Joe B, Garrett MR, Dene H, Rapp JP. Substitution mapping of a blood pressure quantitative trait locus to a 2.73 Mb region on rat chromosome 1. J Hypertens. 2003;21:2077-2084. doi: 10.1097/01. hjh.0000098124.00558.09.
    • (2003) J Hypertens , vol.21 , pp. 2077-2084
    • Joe, B.1    Garrett, M.R.2    Dene, H.3    Rapp, J.P.4
  • 101
    • 63449136073 scopus 로고    scopus 로고
    • Common variants at ten loci influence QT interval duration in the QTGEN Study
    • Newton-Cheh C, Eijgelsheim M, Rice KM, et al. Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat Genet. 2009;41:399-406. doi: 10.1038/ng.364.
    • (2009) Nat Genet , vol.41 , pp. 399-406
    • Newton-Cheh, C.1    Eijgelsheim, M.2    Rice, K.M.3
  • 102
    • 41149176472 scopus 로고    scopus 로고
    • Haplotypic analysis of Wellcome Trust Case Control Consortium data
    • Browning BL, Browning SR. Haplotypic analysis of Wellcome Trust Case Control Consortium data. Hum Genet. 2008;123:273-280. doi: 10.1007/s00439-008-0472-1.
    • (2008) Hum Genet , vol.123 , pp. 273-280
    • Browning, B.L.1    Browning, S.R.2
  • 104
    • 84923336882 scopus 로고    scopus 로고
    • Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension
    • press.
    • Kumarasamy S, Waghulde H, Gopalakrishnan K, Mell B, Morgan E, Joe B. Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension. Nat Commun. In press. doi: 10.1038/ ncomms7252.
    • Nat Commun
    • Kumarasamy, S.1    Waghulde, H.2    Gopalakrishnan, K.3    Mell, B.4    Morgan, E.5    Joe, B.6
  • 105
    • 0032523208 scopus 로고    scopus 로고
    • Construction of a double congenic strain to prove an epistatic interaction on blood pressure between rat chromosomes 2 and 10
    • Rapp JP, Garrett MR, Deng AY. Construction of a double congenic strain to prove an epistatic interaction on blood pressure between rat chromosomes 2 and 10. J Clin Invest. 1998;101:1591-1595. doi: 10.1172/JCI2251.
    • (1998) J Clin Invest , vol.101 , pp. 1591-1595
    • Rapp, J.P.1    Garrett, M.R.2    Deng, A.Y.3
  • 106
    • 0346929380 scopus 로고    scopus 로고
    • Two closely linked interactive blood pressure QTL on rat chromosome 5 defined using congenic Dahl rats
    • Garrett MR, Rapp JP. Two closely linked interactive blood pressure QTL on rat chromosome 5 defined using congenic Dahl rats. Physiol Genomics. 2002;8:81-86. doi: 10.1152/physiolgenomics.00080.2001.
    • (2002) Physiol Genomics , vol.8 , pp. 81-86
    • Garrett, M.R.1    Rapp, J.P.2
  • 107
    • 84882630408 scopus 로고    scopus 로고
    • Theoretical model for gene-gene, gene-environment, and gene-sex interactions based on congenic-strain analysis of blood pressure in Dahl salt-sensitive rats
    • Rapp JP. Theoretical model for gene-gene, gene-environment, and gene-sex interactions based on congenic-strain analysis of blood pressure in Dahl salt-sensitive rats. Physiol Genomics. 2013;45:737-750. doi: 10.1152/physiolgenomics.00046.2013.
    • (2013) Physiol Genomics , vol.45 , pp. 737-750
    • Rapp, J.P.1
  • 110
    • 84919451802 scopus 로고    scopus 로고
    • Genome-wide identification of long noncoding RNAs in rat models of cardiovascular and renal disease
    • Gopalakrishnan K, Kumarasamy S, Mell B, Joe B. Genome-wide identification of long noncoding RNAs in rat models of cardiovascular and renal disease. Hypertension. 2015;65:200-210. doi: 10.1161/ HYPERTENSIONAHA.114.04498.
    • (2015) Hypertension , vol.65 , pp. 200-210
    • Gopalakrishnan, K.1    Kumarasamy, S.2    Mell, B.3    Joe, B.4


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