메뉴 건너뛰기




Volumn 22, Issue 22, 2013, Pages 4451-4459

Modularization and epistatic hierarchy determine homeostatic actions of multiple blood pressure quantitative trait loci

Author keywords

[No Author keywords available]

Indexed keywords

EPISTATIC MODULE 1; EPISTATIC MODULE 2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 84887012469     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt294     Document Type: Article
Times cited : (30)

References (31)
  • 2
    • 80053907554 scopus 로고    scopus 로고
    • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
    • International Consortium for Blood Pressure.
    • International Consortium for Blood Pressure. (2011) Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature, 478, 103-109.
    • (2011) Nature , vol.478 , pp. 103-109
  • 4
    • 79957585975 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians
    • Kato, N., Takeuchi, F., Tabara, Y., Kelly, T.N., Go, M.J., Sim, X., Tay, W.T., Chen, C.H., Zhang, Y., Yamamoto, K. et al. (2011) Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nat. Genet., 43, 531-538.
    • (2011) Nat. Genet. , vol.43 , pp. 531-538
    • Kato, N.1    Takeuchi, F.2    Tabara, Y.3    Kelly, T.N.4    Go, M.J.5    Sim, X.6    Tay, W.T.7    Chen, C.H.8    Zhang, Y.9    Yamamoto, K.10
  • 6
    • 84866158904 scopus 로고    scopus 로고
    • Genetic basis of polygenic hypertension.
    • Deng, A.Y. (2007) Genetic basis of polygenic hypertension. Hum. Mol. Genet., 16, R195-R202.
    • (2007) Hum. Mol. Genet. , vol.16
    • Deng, A.Y.1
  • 7
    • 0033979807 scopus 로고    scopus 로고
    • Genetic analysis of inherited hypertension in the rat
    • Rapp, J.P. (2000) Genetic analysis of inherited hypertension in the rat. Physiol. Rev., 80, 135-172.
    • (2000) Physiol. Rev. , vol.80 , pp. 135-172
    • Rapp, J.P.1
  • 8
    • 3843052401 scopus 로고    scopus 로고
    • Dissecting quantitative trait loci into opposite blood pressure effects on Dahl rat chromosome 8 by congenic strains
    • Ariyarajah, A., Palijan, A., Dutil, J., Prithiviraj, K., Deng, Y. and Deng, A.Y. (2004) Dissecting quantitative trait loci into opposite blood pressure effects on Dahl rat chromosome 8 by congenic strains. J. Hypertens., 22, 1495-1502.
    • (2004) J. Hypertens. , vol.22 , pp. 1495-1502
    • Ariyarajah, A.1    Palijan, A.2    Dutil, J.3    Prithiviraj, K.4    Deng, Y.5    Deng, A.Y.6
  • 9
    • 25144452252 scopus 로고    scopus 로고
    • Severe hypertension caused by alleles from normotensive Lewis for a quantitative trait locus on chromosome 2
    • Eliopoulos, V., Dutil, J., Deng, Y., Grondin, M. and Deng, A.Y. (2005) Severe hypertension caused by alleles from normotensive Lewis for a quantitative trait locus on chromosome 2. Physiol. Genomics, 22, 70-75.
    • (2005) Physiol. Genomics , vol.22 , pp. 70-75
    • Eliopoulos, V.1    Dutil, J.2    Deng, Y.3    Grondin, M.4    Deng, A.Y.5
  • 10
    • 31944435692 scopus 로고    scopus 로고
    • Epistasis, not numbers, regulates functions of clustered Dahl rat quantitative trait loci applicable to human hypertension
    • Charron, S., Duong, C., Menard, A., Roy, J., Eliopoulos, V., Lambert, R. and Deng, A.Y. (2005) Epistasis, not numbers, regulates functions of clustered Dahl rat quantitative trait loci applicable to human hypertension. Hypertension, 46, 1300-1308.
    • (2005) Hypertension , vol.46 , pp. 1300-1308
    • Charron, S.1    Duong, C.2    Menard, A.3    Roy, J.4    Eliopoulos, V.5    Lambert, R.6    Deng, A.Y.7
  • 11
    • 0347133175 scopus 로고    scopus 로고
    • Quantitative trait loci with opposing blood pressure effects demonstrating epistasis on Dahl rat chromosome 3
    • Palijan, A., Dutil, J. and Deng, A.Y. (2003) Quantitative trait loci with opposing blood pressure effects demonstrating epistasis on Dahl rat chromosome 3. Physiol. Genomics, 15, 1-8.
    • (2003) Physiol. Genomics , vol.15 , pp. 1-8
    • Palijan, A.1    Dutil, J.2    Deng, A.Y.3
  • 12
    • 42049114663 scopus 로고    scopus 로고
    • Submegabase resolution of epistatically interacting quantitative trait loci for blood pressure applicable for essential hypertension
    • Chauvet, C., Charron, S., Menard, A., Xiao, C., Roy, J. and Deng, A.Y. (2008) Submegabase resolution of epistatically interacting quantitative trait loci for blood pressure applicable for essential hypertension. J. Hypertens., 26, 893-901.
    • (2008) J. Hypertens. , vol.26 , pp. 893-901
    • Chauvet, C.1    Charron, S.2    Menard, A.3    Xiao, C.4    Roy, J.5    Deng, A.Y.6
  • 13
    • 15744384640 scopus 로고    scopus 로고
    • Multiple quantitative trait loci for blood pressure interacting epistatically and additively on Dahl rat chromosome 2
    • Dutil, J., Eliopoulos, V., Tremblay, J., Hamet, P., Charron, S. and Deng, A.Y. (2005) Multiple quantitative trait loci for blood pressure interacting epistatically and additively on Dahl rat chromosome 2. Hypertension, 45, 557-564.
    • (2005) Hypertension , vol.45 , pp. 557-564
    • Dutil, J.1    Eliopoulos, V.2    Tremblay, J.3    Hamet, P.4    Charron, S.5    Deng, A.Y.6
  • 14
    • 33845488377 scopus 로고    scopus 로고
    • Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats
    • Duong, C., Charron, S., Xiao, C., Hamet, P., Menard, A., Roy, J. and Deng, A.Y. (2006) Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats. Mamm. Genome, 17, 1147-1161.
    • (2006) Mamm. Genome , vol.17 , pp. 1147-1161
    • Duong, C.1    Charron, S.2    Xiao, C.3    Hamet, P.4    Menard, A.5    Roy, J.6    Deng, A.Y.7
  • 16
    • 0013543367 scopus 로고
    • The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes
    • Inoue, A., Yanagisawa, M., Kimura, S., Kasuya, Y., Miyauchi, T., Goto, K. and Masaki, T. (1989) The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc. Natl Acad. Sci. USA, 86, 2863-2867.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 2863-2867
    • Inoue, A.1    Yanagisawa, M.2    Kimura, S.3    Kasuya, Y.4    Miyauchi, T.5    Goto, K.6    Masaki, T.7
  • 17
    • 33845750086 scopus 로고    scopus 로고
    • Substitution mapping in Dahl rats identifies two distinct blood pressure quantitative trait loci within 1.12- and 1.25-mb intervals on chromosome 3
    • Lee, S.J., Liu, J., Westcott, A.M., Vieth, J.A., DeRaedt, S.J., Yang, S., Joe, B. and Cicila, G.T. (2006) Substitution mapping in Dahl rats identifies two distinct blood pressure quantitative trait loci within 1.12- and 1.25-mb intervals on chromosome 3. Genetics, 174, 2203-2213.
    • (2006) Genetics , vol.174 , pp. 2203-2213
    • Lee, S.J.1    Liu, J.2    Westcott, A.M.3    Vieth, J.A.4    DeRaedt, S.J.5    Yang, S.6    Joe, B.7    Cicila, G.T.8
  • 18
    • 79951678251 scopus 로고    scopus 로고
    • Normotension in Lewis and Dahl salt-resistant rats is governed by different genes
    • Crespo, K., Chauvet, C., Blain, M., Menard, A., Roy, J. and Deng, A.Y. (2011) Normotension in Lewis and Dahl salt-resistant rats is governed by different genes. J. Hypertens., 29, 460-465.
    • (2011) J. Hypertens. , vol.29 , pp. 460-465
    • Crespo, K.1    Chauvet, C.2    Blain, M.3    Menard, A.4    Roy, J.5    Deng, A.Y.6
  • 19
    • 0031709918 scopus 로고    scopus 로고
    • Genomic scan and congenic strains for blood pressure quantitative trait loci using Dahl salt-sensitive rats
    • Garrett, M.R., Dene, H., Walder, R., Zhang, Q., Cicila, G.T., Assadnia, S., Deng, A.Y. and Rapp, J.P. (1998) Genomic scan and congenic strains for blood pressure quantitative trait loci using Dahl salt-sensitive rats. Genome Res., 8, 711-723.
    • (1998) Genome Res. , vol.8 , pp. 711-723
    • Garrett, M.R.1    Dene, H.2    Walder, R.3    Zhang, Q.4    Cicila, G.T.5    Assadnia, S.6    Deng, A.Y.7    Rapp, J.P.8
  • 20
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results
    • Lander, E. and Kruglyak, L. (1995) Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat. Genet., 11, 241-247.
    • (1995) Nat. Genet. , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 21
    • 35248832546 scopus 로고    scopus 로고
    • Common genetic variation in the ATP-binding cassette transporter A1, plasma lipids, and risk of coronary heart disease.
    • Jensen, M.K., Pai, J.K., Mukamal, K.J., Overvad, K. and Rimm, E.B. (2007) Common genetic variation in the ATP-binding cassette transporter A1, plasma lipids, and risk of coronary heart disease. Atherosclerosis, 195, e172-e180.
    • (2007) Atherosclerosis , vol.195
    • Jensen, M.K.1    Pai, J.K.2    Mukamal, K.J.3    Overvad, K.4    Rimm, E.B.5
  • 22
    • 54049086122 scopus 로고    scopus 로고
    • Sexual dimorphism on hypertension of quantitative trait loci entrapped in Dahl congenic rats
    • Deng, A.Y., Menard, A., Xiao, C. and Roy, J. (2008) Sexual dimorphism on hypertension of quantitative trait loci entrapped in Dahl congenic rats. Clin. Exp. Hypertens., 30, 511-519.
    • (2008) Clin. Exp. Hypertens. , vol.30 , pp. 511-519
    • Deng, A.Y.1    Menard, A.2    Xiao, C.3    Roy, J.4
  • 23
    • 1842597403 scopus 로고
    • Role of genetic factors in susceptibility to experimental hypertension due to chronic excess salt ingestion
    • Dahl, L.K., Heine, M. and Tassinari, L. (1962) Role of genetic factors in susceptibility to experimental hypertension due to chronic excess salt ingestion. Nature, 194, 480-482.
    • (1962) Nature , vol.194 , pp. 480-482
    • Dahl, L.K.1    Heine, M.2    Tassinari, L.3
  • 24
    • 34249287367 scopus 로고    scopus 로고
    • Neuronal responsiveness to central Na+ in 2 congenic strains of Dahl salt-sensitive rats
    • Huang, B.S., Ahmad, M., Deng, A.Y. and Leenen, F.H. (2007) Neuronal responsiveness to central Na+ in 2 congenic strains of Dahl salt-sensitive rats. Hypertension, 49, 1315-1320.
    • (2007) Hypertension , vol.49 , pp. 1315-1320
    • Huang, B.S.1    Ahmad, M.2    Deng, A.Y.3    Leenen, F.H.4
  • 25
    • 18244377271 scopus 로고    scopus 로고
    • Complete and overlapping congenics proving the existence of a quantitative trait locus for blood pressure on Dahl rat chromosome 17
    • Grondin, M., Eliopoulos, V., Lambert, R., Deng, Y., Ariyarajah, A., Moujahidine, M., Dutil, J., Charron, S. and Deng, A.Y. (2005) Complete and overlapping congenics proving the existence of a quantitative trait locus for blood pressure on Dahl rat chromosome 17. Physiol. Genomics, 21, 112-116.
    • (2005) Physiol. Genomics , vol.21 , pp. 112-116
    • Grondin, M.1    Eliopoulos, V.2    Lambert, R.3    Deng, Y.4    Ariyarajah, A.5    Moujahidine, M.6    Dutil, J.7    Charron, S.8    Deng, A.Y.9
  • 26
    • 34047198196 scopus 로고    scopus 로고
    • Positional cloning of quantitative trait loci for blood pressure: how close are we? A critical perspective
    • Deng, A.Y. (2007) Positional cloning of quantitative trait loci for blood pressure: how close are we? A critical perspective. Hypertension, 49, 740-747.
    • (2007) Hypertension , vol.49 , pp. 740-747
    • Deng, A.Y.1
  • 27
    • 29644436113 scopus 로고    scopus 로고
    • Aloss ofgenomebuffering capacity of Dahl salt-sensitive model to modulate blood pressure as a cause of hypertension.
    • Charron, S., Lambert, R., Eliopoulos, V., Duong, C., Menard, A., Roy, J. and Deng, A.Y. (2005)Aloss ofgenomebuffering capacity of Dahl salt-sensitive model to modulate blood pressure as a cause of hypertension. Hum. Mol. Genet., 14, 3877-3884.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 3877-3884
    • Charron, S.1    Lambert, R.2    Eliopoulos, V.3    Duong, C.4    Menard, A.5    Roy, J.6    Deng, A.Y.7
  • 28
    • 0032523208 scopus 로고    scopus 로고
    • Construction of a double congenic strain to prove an epistatic interaction on blood pressure between rat chromosomes 2 and 10
    • Rapp, J.P., Garret, M.R. and Deng, A.Y. (1998) Construction of a double congenic strain to prove an epistatic interaction on blood pressure between rat chromosomes 2 and 10. J. Clin. Invest., 101, 1591-1595.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1591-1595
    • Rapp, J.P.1    Garret, M.R.2    Deng, A.Y.3
  • 30
    • 79958767623 scopus 로고    scopus 로고
    • alpha-Kinase 2 is a novel candidate gene for inherited hypertension in Dahl rats
    • Chauvet, C., Crespo, K., Menard, A., Wu, Y., Xiao, C., Blain, M., Roy, J. and Deng, A.Y. (2011) alpha-Kinase 2 is a novel candidate gene for inherited hypertension in Dahl rats. J. Hypertens., 29, 1320-1326.
    • (2011) J. Hypertens. , vol.29 , pp. 1320-1326
    • Chauvet, C.1    Crespo, K.2    Menard, A.3    Wu, Y.4    Xiao, C.5    Blain, M.6    Roy, J.7    Deng, A.Y.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.