Targeted disruption of Adamts16 gene in a rat genetic model of hypertension

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 50, 2012, Pages 20555-20559

  Gopalakrishnan, Kathirvel ^a   Kumarasamy, Sivarajan ^a   Abdul Majeed, Shakila ^a   Kalinoski, Andrea L ^a   Morgan, Eric E ^a   Gohara, Amira F ^a   Nauli, Surya M ^a,b   Filipiak, Wanda E ^c   Saunders, Thomas L ^c   Joe, Bina ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b UNIVERSITY OF TOLEDO   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Congenic; GWAS; Mapping; Quantitative trait locus; ZFN mutant

Indexed keywords

ADAMTS PROTEIN; ZINC FINGER NUCLEASE; ADAM PROTEIN; DNA; MUTANT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DAHL SALT SENSITIVE RAT; FLUORESCENCE MICROSCOPY; GENE DELETION; GENE DISRUPTION; GENETIC MODEL; GENETIC TRANSCRIPTION; GENOME; GLOMERULUS CAPILLARY; HYPERTENSION; NONHUMAN; PRIORITY JOURNAL; PULSE WAVE; RAT; SCANNING ELECTRON MICROSCOPY; STOP CODON; SURVIVAL RATE; SYSTOLIC BLOOD PRESSURE; TUNICA MEDIA; VASCULAR ENDOTHELIAL CELL; ANIMAL; BLOOD PRESSURE; BLOOD VESSEL; DISEASE MODEL; FEMALE; GENE TARGETING; GENETICS; GLOMERULUS; HETEROZYGOTE; HOMOZYGOTE; MALE; NUCLEOTIDE SEQUENCE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT STRAIN; VASCULARIZATION;

ADAM PROTEINS; ANIMALS; BASE SEQUENCE; BLOOD PRESSURE; BLOOD VESSELS; DISEASE MODELS, ANIMAL; DNA; FEMALE; GENE TARGETING; HETEROZYGOTE; HOMOZYGOTE; HYPERTENSION; KIDNEY GLOMERULUS; MALE; MUTANT PROTEINS; PULSE WAVE ANALYSIS; RATS; RATS, INBRED DAHL; RATS, MUTANT STRAINS; SEQUENCE DELETION; TUNICA MEDIA;

EID: 84874422612     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1211290109     Document Type: Article

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