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Volumn 18, Issue 9, 2017, Pages 1046-1057

Translation is actively regulated during the differentiation of CD8 + effector T cells

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; LYMPHOCYTE ANTIGEN RECEPTOR; MESSENGER RNA; RIBOSOME PROTEIN; TARGET OF RAPAMYCIN KINASE;

EID: 85027876460     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3795     Document Type: Article
Times cited : (114)

References (51)
  • 1
    • 84867896903 scopus 로고    scopus 로고
    • Transcriptional control of effector and memory CD8+ T cell differentiation
    • Kaech, S.M., Cui, W. Transcriptional control of effector and memory CD8+ T cell differentiation. Nat. Rev. Immunol. 12, 749-761 (2012).
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 749-761
    • Kaech, S.M.1    Cui, W.2
  • 2
    • 35349014587 scopus 로고    scopus 로고
    • Molecular signature of CD8+ T cell exhaustion during chronic viral infection
    • Wherry, E.J., et al. Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity 27, 670-684 (2007).
    • (2007) Immunity , vol.27 , pp. 670-684
    • Wherry, E.J.1
  • 3
    • 0037074012 scopus 로고    scopus 로고
    • Molecular and functional profiling of memory CD8 T cell differentiation
    • Kaech, S.M., Hemby, S., Kersh, E., Ahmed, R. Molecular and functional profiling of memory CD8 T cell differentiation. Cell 111, 837-851 (2002).
    • (2002) Cell , vol.111 , pp. 837-851
    • Kaech, S.M.1    Hemby, S.2    Kersh, E.3    Ahmed, R.4
  • 4
    • 84912096136 scopus 로고    scopus 로고
    • Distinct epigenetic signatures delineate transcriptional programs during virus-specific CD8+ T cell differentiation
    • Russ, B.E., et al. Distinct epigenetic signatures delineate transcriptional programs during virus-specific CD8+ T cell differentiation. Immunity 41, 853-865 (2014).
    • (2014) Immunity , vol.41 , pp. 853-865
    • Russ, B.E.1
  • 5
    • 84885858374 scopus 로고    scopus 로고
    • Epigenetic modifications induced by Blimp-1 regulate CD8+ T cell memory progression during acute virus infection
    • Shin, H.M., et al. Epigenetic modifications induced by Blimp-1 regulate CD8+ T cell memory progression during acute virus infection. Immunity 39, 661-675 (2013).
    • (2013) Immunity , vol.39 , pp. 661-675
    • Shin, H.M.1
  • 6
    • 84884256121 scopus 로고    scopus 로고
    • Global DNA methylation remodeling accompanies CD8 T cell effector function
    • Scharer, C.D., Barwick, B.G., Youngblood, B.A., Ahmed, R., Boss, J.M. Global DNA methylation remodeling accompanies CD8 T cell effector function. J. Immunol. 191, 3419-3429 (2013).
    • (2013) J. Immunol. , vol.191 , pp. 3419-3429
    • Scharer, C.D.1    Barwick, B.G.2    Youngblood, B.A.3    Ahmed, R.4    Boss, J.M.5
  • 7
    • 80053137239 scopus 로고    scopus 로고
    • Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8+ T cells
    • Youngblood, B., et al. Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8+ T cells. Immunity 35, 400-412 (2011).
    • (2011) Immunity , vol.35 , pp. 400-412
    • Youngblood, B.1
  • 8
    • 60149091189 scopus 로고    scopus 로고
    • Regulation of translation initiation in eukaryotes: Mechanisms and biological targets
    • Sonenberg, N., Hinnebusch, A.G. Regulation of translation initiation in eukaryotes: Mechanisms and biological targets. Cell 136, 731-745 (2009).
    • (2009) Cell , vol.136 , pp. 731-745
    • Sonenberg, N.1    Hinnebusch, A.G.2
  • 9
    • 84926409849 scopus 로고    scopus 로고
    • Targeting the translation machinery in cancer
    • Bhat, M., et al. Targeting the translation machinery in cancer. Nat. Rev. Drug Discov. 14, 261-278 (2015).
    • (2015) Nat. Rev. Drug Discov. , vol.14 , pp. 261-278
    • Bhat, M.1
  • 10
    • 84908587395 scopus 로고    scopus 로고
    • Reciprocal signaling between translational control pathways and synaptic proteins in autism spectrum disorders
    • Santini, E., Klann, E. Reciprocal signaling between translational control pathways and synaptic proteins in autism spectrum disorders. Sci. Signal. 7, 10 (2014).
    • (2014) Sci. Signal. , vol.7 , pp. 10
    • Santini, E.1    Klann, E.2
  • 12
    • 84901057834 scopus 로고    scopus 로고
    • Translational control of immune responses: From transcripts to translatomes
    • Piccirillo, C.A., Bjur, E., Topisirovic, I., Sonenberg, N., Larsson, O. Translational control of immune responses: From transcripts to translatomes. Nat. Immunol. 15, 503-511 (2014).
    • (2014) Nat. Immunol. , vol.15 , pp. 503-511
    • Piccirillo, C.A.1    Bjur, E.2    Topisirovic, I.3    Sonenberg, N.4    Larsson, O.5
  • 13
    • 84878831880 scopus 로고    scopus 로고
    • Posttranscriptional control of T cell effector function by aerobic glycolysis
    • Chang, C.H., et al. Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell 153, 1239-1251 (2013).
    • (2013) Cell , vol.153 , pp. 1239-1251
    • Chang, C.H.1
  • 14
    • 84921309472 scopus 로고    scopus 로고
    • The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo
    • Blagih, J., et al. The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo. Immunity 42, 41-54 (2015).
    • (2015) Immunity , vol.42 , pp. 41-54
    • Blagih, J.1
  • 15
    • 33744465772 scopus 로고    scopus 로고
    • Activation of the integrated stress response during T helper cell differentiation
    • Scheu, S., et al. Activation of the integrated stress response during T helper cell differentiation. Nat. Immunol. 7, 644-651 (2006).
    • (2006) Nat. Immunol. , vol.7 , pp. 644-651
    • Scheu, S.1
  • 16
    • 84878513440 scopus 로고    scopus 로고
    • Distinct translational control in CD4+ T cell subsets
    • Bjur, E., et al. Distinct translational control in CD4+ T cell subsets. PLoS Genet. 9, e1003494 (2013).
    • (2013) PLoS Genet. , vol.9 , pp. e1003494
    • Bjur, E.1
  • 17
    • 78650510609 scopus 로고    scopus 로고
    • MTOR: From growth signal integration to cancer, diabetes and ageing
    • Zoncu, R., Efeyan, A., Sabatini, D.M. mTOR: From growth signal integration to cancer, diabetes and ageing. Nat. Rev. Mol. Cell Biol. 12, 21-35 (2011).
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 21-35
    • Zoncu, R.1    Efeyan, A.2    Sabatini, D.M.3
  • 18
    • 67650074206 scopus 로고    scopus 로고
    • MTOR regulates memory CD8 T-cell differentiation
    • Araki, K., et al. mTOR regulates memory CD8 T-cell differentiation. Nature 460, 108-112 (2009).
    • (2009) Nature , vol.460 , pp. 108-112
    • Araki, K.1
  • 19
    • 67650096912 scopus 로고    scopus 로고
    • Enhancing CD8 T-cell memory by modulating fatty acid metabolism
    • Pearce, E.L., et al. Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature 460, 103-107 (2009).
    • (2009) Nature , vol.460 , pp. 103-107
    • Pearce, E.L.1
  • 20
    • 0037340417 scopus 로고    scopus 로고
    • Lineage relationship and protective immunity of memory CD8+ T cell subsets
    • Wherry, E.J., et al. Lineage relationship and protective immunity of memory CD8+ T cell subsets. Nat. Immunol. 4, 225-234 (2003).
    • (2003) Nat. Immunol. , vol.4 , pp. 225-234
    • Wherry, E.J.1
  • 21
    • 84898739668 scopus 로고    scopus 로고
    • Haematopoietic stem cells require a highly regulated protein synthesis rate
    • Signer, R.A., Magee, J.A., Salic, A., Morrison, S.J. Haematopoietic stem cells require a highly regulated protein synthesis rate. Nature 509, 49-54 (2014).
    • (2014) Nature , vol.509 , pp. 49-54
    • Signer, R.A.1    Magee, J.A.2    Salic, A.3    Morrison, S.J.4
  • 22
    • 79956325949 scopus 로고    scopus 로고
    • Spatial coupling of mTOR and autophagy augments secretory phenotypes
    • Narita, M., et al. Spatial coupling of mTOR and autophagy augments secretory phenotypes. Science 332, 966-970 (2011).
    • (2011) Science , vol.332 , pp. 966-970
    • Narita, M.1
  • 23
    • 0037111237 scopus 로고    scopus 로고
    • A unique mechanism for innate cytokine promotion of T cell responses to viral infections
    • Pien, G.C., Nguyen, K.B., Malmgaard, L., Satoskar, A.R., Biron, C.A. A unique mechanism for innate cytokine promotion of T cell responses to viral infections. J. Immunol. 169, 5827-5837 (2002).
    • (2002) J. Immunol. , vol.169 , pp. 5827-5837
    • Pien, G.C.1    Nguyen, K.B.2    Malmgaard, L.3    Satoskar, A.R.4    Biron, C.A.5
  • 24
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian, A., et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. USA 102, 15545-15550 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1
  • 25
    • 84958925144 scopus 로고    scopus 로고
    • Compendium of immune signatures identifies conserved and species-specific biology in response to inflammation
    • Godec, J., et al. Compendium of immune signatures identifies conserved and species-specific biology in response to inflammation. Immunity 44, 194-206 (2016).
    • (2016) Immunity , vol.44 , pp. 194-206
    • Godec, J.1
  • 26
    • 84930959981 scopus 로고    scopus 로고
    • The race to decipher the top secrets of TOP mRNAs
    • Meyuhas, O., Kahan, T. The race to decipher the top secrets of TOP mRNAs. Biochim. Biophys. Acta 1849, 801-811 (2015).
    • (2015) Biochim. Biophys. Acta , vol.1849 , pp. 801-811
    • Meyuhas, O.1    Kahan, T.2
  • 27
    • 84901700198 scopus 로고    scopus 로고
    • Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner
    • Miloslavski, R., et al. Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner. J. Mol. Cell Biol. 6, 255-266 (2014).
    • (2014) J. Mol. Cell Biol. , vol.6 , pp. 255-266
    • Miloslavski, R.1
  • 28
    • 84860527756 scopus 로고    scopus 로고
    • A unifying model for mTORC1-mediated regulation of mRNA translation
    • Thoreen, C.C., et al. A unifying model for mTORC1-mediated regulation of mRNA translation. Nature 485, 109-113 (2012).
    • (2012) Nature , vol.485 , pp. 109-113
    • Thoreen, C.C.1
  • 29
    • 84862777192 scopus 로고    scopus 로고
    • The translational landscape of mTOR signalling steers cancer initiation and metastasis
    • Hsieh, A.C., et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature 485, 55-61 (2012).
    • (2012) Nature , vol.485 , pp. 55-61
    • Hsieh, A.C.1
  • 30
    • 0347382593 scopus 로고    scopus 로고
    • Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
    • Kaech, S.M., et al. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat. Immunol. 4, 1191-1198 (2003).
    • (2003) Nat. Immunol. , vol.4 , pp. 1191-1198
    • Kaech, S.M.1
  • 31
    • 34548027000 scopus 로고    scopus 로고
    • Inflammation directs memory precursor and short-lived effector CD8+ T cell fates via the graded expression of T-bet transcription factor
    • Joshi, N.S., et al. Inflammation directs memory precursor and short-lived effector CD8+ T cell fates via the graded expression of T-bet transcription factor. Immunity 27, 281-295 (2007).
    • (2007) Immunity , vol.27 , pp. 281-295
    • Joshi, N.S.1
  • 32
    • 41149099559 scopus 로고    scopus 로고
    • Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
    • Sarkar, S., et al. Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates. J. Exp. Med. 205, 625-640 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 625-640
    • Sarkar, S.1
  • 33
    • 84958213278 scopus 로고    scopus 로고
    • Redefining the translational status of 80S monosomes
    • Heyer, E.E., Moore, M.J. Redefining the translational status of 80S monosomes. Cell 164, 757-769 (2016).
    • (2016) Cell , vol.164 , pp. 757-769
    • Heyer, E.E.1    Moore, M.J.2
  • 34
    • 0037383592 scopus 로고    scopus 로고
    • Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
    • Wherry, E.J., Blattman, J.N., Murali-Krishna, K., van der Most, R., Ahmed, R. Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J. Virol. 77, 4911-4927 (2003).
    • (2003) J. Virol. , vol.77 , pp. 4911-4927
    • Wherry, E.J.1    Blattman, J.N.2    Murali-Krishna, K.3    Van Der Most, R.4    Ahmed, R.5
  • 35
    • 84887415150 scopus 로고    scopus 로고
    • MTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation
    • Morita, M., et al. mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation. Cell Metab. 18, 698-711 (2013).
    • (2013) Cell Metab. , vol.18 , pp. 698-711
    • Morita, M.1
  • 36
    • 84861872213 scopus 로고    scopus 로고
    • Distinct perturbation of the translatome by the antidiabetic drug metformin
    • Larsson, O., et al. Distinct perturbation of the translatome by the antidiabetic drug metformin. Proc. Natl. Acad. Sci. USA 109, 8977-8982 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 8977-8982
    • Larsson, O.1
  • 37
    • 84930363624 scopus 로고    scopus 로고
    • MTOR signaling in cellular and organismal energetics
    • Albert, V., Hall, M.N. mTOR signaling in cellular and organismal energetics. Curr. Opin. Cell Biol. 33, 55-66 (2015).
    • (2015) Curr. Opin. Cell Biol. , vol.33 , pp. 55-66
    • Albert, V.1    Hall, M.N.2
  • 38
    • 84896629473 scopus 로고    scopus 로고
    • Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program
    • Chauvin, C., et al. Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program. Oncogene 33, 474-483 (2014).
    • (2014) Oncogene , vol.33 , pp. 474-483
    • Chauvin, C.1
  • 39
    • 84929008302 scopus 로고    scopus 로고
    • MTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation
    • Pollizzi, K.N., et al. mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation. J. Clin. Invest. 125, 2090-2108 (2015).
    • (2015) J. Clin. Invest. , vol.125 , pp. 2090-2108
    • Pollizzi, K.N.1
  • 40
    • 84957963858 scopus 로고    scopus 로고
    • Mammalian target of rapamycin complex 2 controls CD8 T cell memory differentiation in a Foxo1-dependent manner
    • Zhang, L., et al. Mammalian target of rapamycin complex 2 controls CD8 T cell memory differentiation in a Foxo1-dependent manner. Cell Rep. 14, 1206-1217 (2016).
    • (2016) Cell Rep. , vol.14 , pp. 1206-1217
    • Zhang, L.1
  • 41
    • 79952293503 scopus 로고    scopus 로고
    • Activation of mTORC2 by association with the ribosome
    • Zinzalla, V., Stracka, D., Oppliger, W., Hall, M.N. Activation of mTORC2 by association with the ribosome. Cell 144, 757-768 (2011).
    • (2011) Cell , vol.144 , pp. 757-768
    • Zinzalla, V.1    Stracka, D.2    Oppliger, W.3    Hall, M.N.4
  • 42
    • 84988410229 scopus 로고    scopus 로고
    • Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection
    • He, R., et al. Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection. Nature 537, 412-428 (2016).
    • (2016) Nature , vol.537 , pp. 412-428
    • He, R.1
  • 43
    • 84988266244 scopus 로고    scopus 로고
    • Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
    • Im, S.J., et al. Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy. Nature 537, 417-421 (2016).
    • (2016) Nature , vol.537 , pp. 417-421
    • Im, S.J.1
  • 44
    • 84981285538 scopus 로고    scopus 로고
    • CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles
    • Leong, Y.A., et al. CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles. Nat. Immunol. 17, 1187-1196 (2016).
    • (2016) Nat. Immunol. , vol.17 , pp. 1187-1196
    • Leong, Y.A.1
  • 45
    • 85002609650 scopus 로고    scopus 로고
    • T cell factor 1-expressing memory-like CD8+ T cells sustain the immune response to chronic viral infections
    • Utzschneider, D.T., et al. T cell factor 1-expressing memory-like CD8+ T cells sustain the immune response to chronic viral infections. Immunity 45, 415-427 (2016).
    • (2016) Immunity , vol.45 , pp. 415-427
    • Utzschneider, D.T.1
  • 46
    • 85014738071 scopus 로고    scopus 로고
    • The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness
    • Wu, T., et al. The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness. Science Immunol. 1, 8593 (2016).
    • (2016) Science Immunol. , vol.1 , pp. 8593
    • Wu, T.1
  • 47
    • 77954956266 scopus 로고    scopus 로고
    • Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8+ T cell differentiation
    • Wirth, T.C., et al. Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8+ T cell differentiation. Immunity 33, 128-140 (2010).
    • (2010) Immunity , vol.33 , pp. 128-140
    • Wirth, T.C.1
  • 48
    • 84911201387 scopus 로고    scopus 로고
    • Molecular regulation of effector and memory T cell differentiation
    • Chang, J.T., Wherry, E.J., Goldrath, A.W. Molecular regulation of effector and memory T cell differentiation. Nat. Immunol. 15, 1104-1115 (2014).
    • (2014) Nat. Immunol. , vol.15 , pp. 1104-1115
    • Chang, J.T.1    Wherry, E.J.2    Goldrath, A.W.3
  • 49
    • 41149133368 scopus 로고    scopus 로고
    • Translational control of the innate immune response through IRF-7
    • Colina, R., et al. Translational control of the innate immune response through IRF-7. Nature 452, 323-328 (2008).
    • (2008) Nature , vol.452 , pp. 323-328
    • Colina, R.1
  • 50
    • 78649775562 scopus 로고    scopus 로고
    • Enrichment map: A network-based method for gene-set enrichment visualization and interpretation
    • Merico, D., Isserlin, R., Stueker, O., Emili, A., Bader, G.D. Enrichment map: A network-based method for gene-set enrichment visualization and interpretation. PLoS One 5, e13984 (2010).
    • (2010) PLoS One , vol.5 , pp. e13984
    • Merico, D.1    Isserlin, R.2    Stueker, O.3    Emili, A.4    Bader, G.D.5
  • 51
    • 84951019738 scopus 로고    scopus 로고
    • Meta-and orthogonal integration of influenza OMICs" data defines a role for ubr4 in virus budding
    • Tripathi, S., et al. Meta-and orthogonal integration of influenza "OMICs" data defines a role for ubr4 in virus budding. Cell Host Microbe 18, 723-735 (2015).
    • (2015) Cell Host Microbe , vol.18 , pp. 723-735
    • Tripathi, S.1


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