Pomegranate ellagitannin-gut microbial-derived metabolites, urolithins, inhibit neuroinflammation in vitro

Nutritional Neuroscience

Volumn 22, Issue 3, 2019, Pages 185-195

  DaSilva, Nicholas A ^a   Nahar, Pragati P ^a   Ma, Hang ^a   Eid, Aseel ^a   Wei, Zhengxi ^a   Meschwitz, Susan ^b   Zawia, Nasser H ^a   Slitt, Angela L ^a   Seeram, Navindra P ^a  

^a UNIVERSITY OF RHODE ISLAND   (United States)

^b SALVE REGINA UNIVERSITY   (United States)

Author keywords

Gut microflora; Neuroinflammation; Neuroprotective; Pomegranate; Urolithins

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 9; LIPOPOLYSACCHARIDE; NEUROPROTECTIVE AGENT; POMEGRANATE EXTRACT; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; UROLITHINS; 3,8-DIHYDROXY-6H-DIBENZO(B,D)PYRAN-6-ONE; AUTACOID; COUMARIN DERIVATIVE; ELLAGITANNIN; PLANT EXTRACT; TANNIN; UROLITHIN B;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; GENE EXPRESSION; HIPPOCAMPUS; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE FLORA; METABOLITE; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; POMEGRANATE; POMEGRANATE ELLAGITANNIN; PRIORITY JOURNAL; RNA EXTRACTION; SH-SY5Y CELL LINE; ANIMAL; CELL LINE; CHEMICALLY INDUCED; DRUG EFFECT; ENCEPHALITIS; LYTHRACEAE; METABOLISM; NERVE CELL; TRANSGENIC MOUSE; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CELL LINE; CELL LINE, TUMOR; COUMARINS; ENCEPHALITIS; GASTROINTESTINAL MICROBIOME; HIPPOCAMPUS; HUMANS; HYDROLYZABLE TANNINS; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MICE, TRANSGENIC; MICROGLIA; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PLANT EXTRACTS; PUNICACEAE;

EID: 85027020877     PISSN: 1028415X     EISSN: 14768305     Source Type: Journal    
DOI: 10.1080/1028415X.2017.1360558     Document Type: Article

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