Fate of Microbial Metabolites of Dietary Polyphenols in Rats: Is the Brain Their Target Destination?

ACS Chemical Neuroscience

Volumn 6, Issue 8, 2015, Pages 1341-1352

  Gasperotti, Mattia ^a   Passamonti, Sabina ^b   Tramer, Federica ^b   Masuero, Domenico ^a   Guella, Graziano ^c   Mattivi, Fulvio ^a   Vrhovsek, Urska ^a  

^a RESEARCH AND INNOVATION CENTRE   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

^c UNIVERSITY OF TRENTO   (Italy)

Author keywords

brain; fruit consumption; gut microbiota; mass spectrometry; Polyphenols; target metabolomics

Indexed keywords

3 (3 HYDROXYPHENYL)PROPANOIC ACID; 3 (4 HYDROXYPHENYL)PROPANOIC ACID; 3 HYDROXYPHENYLACETIC ACID; 3,4 DIHYDROXYPHENYL ACETIC ACID; 4 HYDROXYBENZOIC ACID; 4 HYDROXYHIPPURIC ACID; ALPHA COUMARIC ACID; CAFFEIC ACID; CATECHOL; DRUG METABOLITE; GALLIC ACID; HOMOVANILLIC ACID; M COUMARIC ACID; O COUMARIC ACID; PARA COUMARIC ACID; PHLOROGLUCINOL; POLYPHENOL DERIVATIVE; PROTOCATECHUIC ACID; PYROGALLOL; SINAPIC ACID; TRANS FERULIC ACID; TRANS ISOFERULIC ACID; UNCLASSIFIED DRUG; UROLITHIN A; UROLITHIN B; VANILLIC ACID; CARBOXYLIC ACID; POLYPHENOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BRAIN; BRAIN CHEMISTRY; CONCENTRATION AT STEADY-STATE; CONTROLLED STUDY; DIETARY INTAKE; DRUG ABSORPTION; DRUG BRAIN LEVEL; DRUG EXCRETION; DRUG METABOLISM; ELIMINATION RATE CONSTANT; INTESTINE FLORA; MALE; METABOLOMICS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; TANDEM MASS SPECTROMETRY; TARGET ORGAN; TISSUE DISTRIBUTION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINALYSIS; URINARY EXCRETION; ANIMAL; ANIMAL MODEL; CARDIAC MUSCLE; CHEMICAL STRUCTURE; CHEMISTRY; DIET; FRUIT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY; KINETICS; LIVER; METABOLISM; PHYSIOLOGY; WISTAR RAT;

ANIMALIA; RATTUS;

ADMINISTRATION, INTRAVENOUS; ANIMALS; BRAIN; CARBOXYLIC ACIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIET; FRUIT; GASTROINTESTINAL MICROBIOME; KIDNEY; KINETICS; LIVER; MALE; MODELS, ANIMAL; MOLECULAR STRUCTURE; MYOCARDIUM; POLYPHENOLS; RATS, WISTAR; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION;

EID: 84939780334     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/acschemneuro.5b00051     Document Type: Article

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