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Volumn 3, Issue , 2017, Pages

Demystifying traditional herbal medicine with modern approaches

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PRODUCT;

EID: 85026659438     PISSN: None     EISSN: 20550278     Source Type: Journal    
DOI: 10.1038/nplants.2017.109     Document Type: Review
Times cited : (302)

References (66)
  • 1
    • 80052929893 scopus 로고    scopus 로고
    • Accessed 1 June 2017
    • The Plant List (accessed 1 June 2017); http://www.theplantlist.org/
    • The Plant List
  • 2
    • 84862996527 scopus 로고    scopus 로고
    • The rise of chemodiversity in plants
    • Weng, J.-K., Philippe, R. N. & Noel, J. P. The rise of chemodiversity in plants. Science 336, 1660-1677 (2012).
    • (2012) Science , vol.336 , pp. 1660-1677
    • Weng, J.-K.1    Philippe, R.N.2    Noel, J.P.3
  • 3
    • 84866237045 scopus 로고    scopus 로고
    • Neanderthal medics? Evidence for food, cooking, and medicinal plants entrapped in dental calculus
    • Hardy, K. et al. Neanderthal medics? Evidence for food, cooking, and medicinal plants entrapped in dental calculus. Naturwissenschaften 99, 617-626 (2012).
    • (2012) Naturwissenschaften , vol.99 , pp. 617-626
    • Hardy, K.1
  • 4
    • 0026551822 scopus 로고
    • Medicinal plants in a Middle Paleolithic grave Shanidar IV?
    • Lietava, J. Medicinal plants in a Middle Paleolithic grave Shanidar IV? J. Ethnopharmacol. 35, 263-266 (1992).
    • (1992) J. Ethnopharmacol. , vol.35 , pp. 263-266
    • Lietava, J.1
  • 5
    • 76149107484 scopus 로고    scopus 로고
    • Herbal medicine in ancient Egypt
    • Aboelsoud, N. H. Herbal medicine in ancient Egypt. J. Med. Plants Res. 4, 82-86 (2010).
    • (2010) J. Med. Plants Res. , vol.4 , pp. 82-86
    • Aboelsoud, N.H.1
  • 8
    • 84922106952 scopus 로고    scopus 로고
    • An analysis of FDA-approved drugs: Natural products and their derivatives
    • Patridge, E., Gareiss, P., Kinch, M. S. & Hoyer, D. An analysis of FDA-approved drugs: natural products and their derivatives. Drug Discov. Today 21, 204-207 (2015).
    • (2015) Drug Discov. Today , vol.21 , pp. 204-207
    • Patridge, E.1    Gareiss, P.2    Kinch, M.S.3    Hoyer, D.4
  • 9
    • 0015211527 scopus 로고
    • Plant antitumor agents. VI. the isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
    • Wani, M. C., Taylor, H. L., Wall, M. E., Coggon, P. & McPhail, A. T. Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J. Am. Chem. Soc. 93, 2325-2327 (1971).
    • (1971) J. Am. Chem. Soc. , vol.93 , pp. 2325-2327
    • Wani, M.C.1    Taylor, H.L.2    Wall, M.E.3    Coggon, P.4    McPhail, A.T.5
  • 10
    • 1842791311 scopus 로고
    • Vinca alkaloids. III.1 Characterization of leurosine and vincaleukoblastine, new alkaloids from Vinca Rosea Linn
    • Neuss, N., Gorman, M., Svoboda, G. H., Maciak, G. & Beer, C. T. Vinca alkaloids. III.1 Characterization of leurosine and vincaleukoblastine, new alkaloids from Vinca Rosea Linn. J. Am. Chem. Soc. 81, 4754-4755 (1959).
    • (1959) J. Am. Chem. Soc. , vol.81 , pp. 4754-4755
    • Neuss, N.1    Gorman, M.2    Svoboda, G.H.3    Maciak, G.4    Beer, C.T.5
  • 11
    • 14744297337 scopus 로고    scopus 로고
    • Combination effects of herbs in a multi-herbal formula: Expression of Juzen-taiho-to's immuno-modulatory activity on the intestinal immune system
    • Kiyohara, H., Matsumoto, T. & Yamada, H. Combination effects of herbs in a multi-herbal formula: expression of Juzen-taiho-to's immuno-modulatory activity on the intestinal immune system. eCAM 1, 83-91 (2004).
    • (2004) ECAM , vol.1 , pp. 83-91
    • Kiyohara, H.1    Matsumoto, T.2    Yamada, H.3
  • 12
    • 0035925096 scopus 로고    scopus 로고
    • Phytochemistry and medicinal plants
    • Phillipson, J. D. Phytochemistry and medicinal plants. Phytochemistry 56, 237-243 (2001).
    • (2001) Phytochemistry , vol.56 , pp. 237-243
    • Phillipson, J.D.1
  • 14
    • 84861096654 scopus 로고    scopus 로고
    • Crystal structure of the micro-opioid receptor bound to a morphinan antagonist
    • Manglik, A. et al. Crystal structure of the micro-opioid receptor bound to a morphinan antagonist. Nature 485, 321-326 (2012).
    • (2012) Nature , vol.485 , pp. 321-326
    • Manglik, A.1
  • 15
    • 84939795137 scopus 로고    scopus 로고
    • Structural insights into μ-opioid receptor activation
    • Huang, W. et al. Structural insights into μ-opioid receptor activation. Nature 524, 315-321 (2015).
    • (2015) Nature , vol.524 , pp. 315-321
    • Huang, W.1
  • 16
    • 0031470828 scopus 로고    scopus 로고
    • How opioids inhibit GABA-mediated neurotransmission
    • Vaughan, C. W., Ingram, S. L., Connor, M. A. & Christie, M. J. How opioids inhibit GABA-mediated neurotransmission. Nature 390, 611-614 (1997).
    • (1997) Nature , vol.390 , pp. 611-614
    • Vaughan, C.W.1    Ingram, S.L.2    Connor, M.A.3    Christie, M.J.4
  • 17
    • 0035942226 scopus 로고    scopus 로고
    • The binding conformation of Taxol in ß-tubulin: A model based on electron crystallographic density
    • Snyder, J. P., Nettles, J. H., Cornett, B., Downing, K. H. & Nogales, E. The binding conformation of Taxol in ß-tubulin: a model based on electron crystallographic density. Proc. Natl Acad. Sci. USA 98, 5312-5316 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 5312-5316
    • Snyder, J.P.1    Nettles, J.H.2    Cornett, B.3    Downing, K.H.4    Nogales, E.5
  • 18
    • 0029061777 scopus 로고
    • Treatment of HIV-associated Kaposi's sarcoma with paclitaxel
    • Saville, M. W. et al. Treatment of HIV-associated Kaposi's sarcoma with paclitaxel. Lancet 346, 26-28 (1995).
    • (1995) Lancet , vol.346 , pp. 26-28
    • Saville, M.W.1
  • 19
    • 19544393159 scopus 로고    scopus 로고
    • Structural basis for the regulation of tubulin by vinblastine
    • Gigant, B. et al. Structural basis for the regulation of tubulin by vinblastine. Nature 435, 519-522 (2005).
    • (2005) Nature , vol.435 , pp. 519-522
    • Gigant, B.1
  • 20
    • 84922365628 scopus 로고    scopus 로고
    • Omacetaxine mepesuccinate in patients with advanced chronic myeloid leukemia with resistance or intolerance to tyrosine kinase inhibitors
    • Khoury, H. J. et al. Omacetaxine mepesuccinate in patients with advanced chronic myeloid leukemia with resistance or intolerance to tyrosine kinase inhibitors. Leuk. Lymphoma 56, 120-127 (2015).
    • (2015) Leuk. Lymphoma , vol.56 , pp. 120-127
    • Khoury, H.J.1
  • 21
    • 84908546298 scopus 로고    scopus 로고
    • Structural basis for the inhibition of the eukaryotic ribosome
    • Garreau de Loubresse, N. et al. Structural basis for the inhibition of the eukaryotic ribosome. Nature 513, 517-522 (2014).
    • (2014) Nature , vol.513 , pp. 517-522
    • Garreau De Loubresse, N.1
  • 22
    • 84898757160 scopus 로고    scopus 로고
    • Omacetaxine: A protein translation inhibitor for treatment of chronic myelogenous leukemia
    • Gandhi, V., Plunkett, W. & Cortes, J. E. Omacetaxine: a protein translation inhibitor for treatment of chronic myelogenous leukemia. Clin. Cancer Res. 20, 1735-1740 (2014).
    • (2014) Clin. Cancer Res. , vol.20 , pp. 1735-1740
    • Gandhi, V.1    Plunkett, W.2    Cortes, J.E.3
  • 23
    • 84934299791 scopus 로고    scopus 로고
    • Small-molecule induction of phospho-eIF4E sumoylation and degradation via targeting its phosphorylated serine 209 residue
    • Gu, Y. et al. Small-molecule induction of phospho-eIF4E sumoylation and degradation via targeting its phosphorylated serine 209 residue. Oncotarget 6, 15111-15121 (2015).
    • (2015) Oncotarget , vol.6 , pp. 15111-15121
    • Gu, Y.1
  • 24
    • 0037180432 scopus 로고    scopus 로고
    • The mechanism of topoisomerase i poisoning by a camptothecin analog
    • Staker, B. L. et al. The mechanism of topoisomerase I poisoning by a camptothecin analog. Proc. Natl Acad. Sci. USA 99, 15387-15392 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 15387-15392
    • Staker, B.L.1
  • 25
    • 0036399299 scopus 로고    scopus 로고
    • Camptothecins
    • Ulukan, H. & Swaan, P. W. Camptothecins. Drugs 62, 2039-2057 (2002).
    • (2002) Drugs , vol.62 , pp. 2039-2057
    • Ulukan, H.1    Swaan, P.W.2
  • 26
    • 0031810637 scopus 로고    scopus 로고
    • Podophyllotoxins: Current status and recent developments
    • Damayanthi, Y. & Lown, J. W. Podophyllotoxins: current status and recent developments. Curr. Med. Chem. 5, 205-252 (1998).
    • (1998) Curr. Med. Chem. , vol.5 , pp. 205-252
    • Damayanthi, Y.1    Lown, J.W.2
  • 27
    • 79960676884 scopus 로고    scopus 로고
    • Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide
    • Wu, C. C. et al. Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide. Science 333, 459-462 (2011).
    • (2011) Science , vol.333 , pp. 459-462
    • Wu, C.C.1
  • 28
    • 84885624465 scopus 로고    scopus 로고
    • Berbamine inhibits the growth of liver cancer cells and cancer-initiating cells by targeting Ca2+/calmodulin-dependent protein kinase II
    • Meng, Z. P. et al. Berbamine inhibits the growth of liver cancer cells and cancer-initiating cells by targeting Ca2+/calmodulin-dependent protein kinase II. Mol. Cancer Ther. 12, 2067-2077 (2013).
    • (2013) Mol. Cancer Ther. , vol.12 , pp. 2067-2077
    • Meng, Z.P.1
  • 29
    • 84870737638 scopus 로고    scopus 로고
    • CaMKII ?, a critical regulator of CML stem/progenitor cells, is a target of the natural product berbamine
    • Gu, Y. et al. CaMKII ?, a critical regulator of CML stem/progenitor cells, is a target of the natural product berbamine. Blood 120, 4829-4839 (2012).
    • (2012) Blood , vol.120 , pp. 4829-4839
    • Gu, Y.1
  • 30
    • 0037932865 scopus 로고    scopus 로고
    • Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
    • Dolma, S., Lessnick, S. L., Hahn, W. C. & Stockwell, B. R. Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells. Cancer Cell 3, 285-296 (2003).
    • (2003) Cancer Cell , vol.3 , pp. 285-296
    • Dolma, S.1    Lessnick, S.L.2    Hahn, W.C.3    Stockwell, B.R.4
  • 31
    • 84944789845 scopus 로고    scopus 로고
    • Bouvardin is a radiation modulator with a novel mechanism of action
    • Stickel, S. A., Gomes, N. P., Frederick, B., Raben, D. & Su, T. T. Bouvardin is a radiation modulator with a novel mechanism of action. Radiat. Res. 184, 392-403 (2015).
    • (2015) Radiat. Res. , vol.184 , pp. 392-403
    • Stickel, S.A.1    Gomes, N.P.2    Frederick, B.3    Raben, D.4    Su, T.T.5
  • 32
    • 0020386240 scopus 로고
    • The mode of action of the antitumor drug bouvardin, an inhibitor of protein synthesis in eukaryotic cells
    • Zalacain, M., Zaera, E., Vazquez, D. & Jimenez, A. The mode of action of the antitumor drug bouvardin, an inhibitor of protein synthesis in eukaryotic cells. FEBS Lett. 148, 95-97 (1982).
    • (1982) FEBS Lett. , vol.148 , pp. 95-97
    • Zalacain, M.1    Zaera, E.2    Vazquez, D.3    Jimenez, A.4
  • 33
    • 84870208120 scopus 로고    scopus 로고
    • Medicinal plants: A source of anti-parasitic secondary metabolites
    • Wink, M. Medicinal plants: a source of anti-parasitic secondary metabolites. Molecules 17, 12771-12791 (2012).
    • (2012) Molecules , vol.17 , pp. 12771-12791
    • Wink, M.1
  • 34
    • 80053976628 scopus 로고    scopus 로고
    • The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine
    • Tu, Y. The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine. Nat. Med. 17, 1217-1220 (2011).
    • (2011) Nat. Med. , vol.17 , pp. 1217-1220
    • Tu, Y.1
  • 35
    • 84951850850 scopus 로고    scopus 로고
    • Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum
    • Wang, J. et al. Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum. Nat. Commun. 6, 10111 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 10111
    • Wang, J.1
  • 36
    • 84966376846 scopus 로고    scopus 로고
    • Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRL/lpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation
    • Wu, Y. et al. Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRL/lpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation. Cell. Mol. Immunol. 13, 379-390 (2016).
    • (2016) Cell. Mol. Immunol. , vol.13 , pp. 379-390
    • Wu, Y.1
  • 37
    • 85007346465 scopus 로고    scopus 로고
    • Artemisinins target GABAA receptor signaling and impair a cell identity
    • Li, J. et al. Artemisinins target GABAA receptor signaling and impair a cell identity. Cell 168, 86-100 (2017).
    • (2017) Cell , vol.168 , pp. 86-100
    • Li, J.1
  • 38
    • 84873856866 scopus 로고    scopus 로고
    • Development of artemisinin compounds for cancer treatment
    • Lai, H. C., Singh, N. P. & Sasaki, T. Development of artemisinin compounds for cancer treatment. Invest. New Drugs 31, 230-246 (2013).
    • (2013) Invest. New Drugs , vol.31 , pp. 230-246
    • Lai, H.C.1    Singh, N.P.2    Sasaki, T.3
  • 39
    • 10744232323 scopus 로고    scopus 로고
    • Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors
    • Samochocki, M. et al. Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors. J. Pharmacol. Exp. Ther. 305, 1024-1036 (2003).
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 1024-1036
    • Samochocki, M.1
  • 40
    • 0031015343 scopus 로고    scopus 로고
    • Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A
    • Raves, M. L. et al. Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A. Nat. Struct. Biol. 4, 57-63 (1997).
    • (1997) Nat. Struct. Biol. , vol.4 , pp. 57-63
    • Raves, M.L.1
  • 41
    • 50649113266 scopus 로고    scopus 로고
    • [+]-Huperzine A treatment protects against N-methyl-d-aspartate-induced seizure/status epilepticus in rats
    • Coleman, B. R. et al. [+]-Huperzine A treatment protects against N-methyl-d-aspartate-induced seizure/status epilepticus in rats. Chem. Biol. Interact. 175, 387-395 (2008).
    • (2008) Chem. Biol. Interact. , vol.175 , pp. 387-395
    • Coleman, B.R.1
  • 42
    • 33746342145 scopus 로고    scopus 로고
    • Multiple conformations of phosphodiesterase-5: Implications for enzyme function and drug development
    • Wang, H. et al. Multiple conformations of phosphodiesterase-5: implications for enzyme function and drug development. J. Biol. Chem. 281, 21469-21479 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 21469-21479
    • Wang, H.1
  • 43
    • 0037434895 scopus 로고    scopus 로고
    • Effect of anti-IgE therapy in patients with peanut allergy
    • Leung, D. Y. et al. Effect of anti-IgE therapy in patients with peanut allergy. N. Engl. J. Med. 348, 986-993 (2003).
    • (2003) N. Engl. J. Med. , vol.348 , pp. 986-993
    • Leung, D.Y.1
  • 44
    • 11344281218 scopus 로고    scopus 로고
    • The Chinese herbal medicine formula FAHF-2 completely blocks anaphylactic reactions in a murine model of peanut allergy
    • Srivastava, K. D. et al. The Chinese herbal medicine formula FAHF-2 completely blocks anaphylactic reactions in a murine model of peanut allergy. J. Allergy Clin. Immunol. 115, 171-178 (2005).
    • (2005) J. Allergy Clin. Immunol. , vol.115 , pp. 171-178
    • Srivastava, K.D.1
  • 45
    • 59449107523 scopus 로고    scopus 로고
    • Food Allergy Herbal Formula-2 silences peanut-induced anaphylaxis for a prolonged posttreatment period via IFN-?-producing CD8+ T cells
    • Srivastava, K. D. et al. Food Allergy Herbal Formula-2 silences peanut-induced anaphylaxis for a prolonged posttreatment period via IFN-?-producing CD8+ T cells. J. Allergy Clin. Immunol. 123, 443-451 (2009).
    • (2009) J. Allergy Clin. Immunol. , vol.123 , pp. 443-451
    • Srivastava, K.D.1
  • 46
    • 44149099071 scopus 로고    scopus 로고
    • Pharmacological and immunological effects of individual herbs in the Food Allergy Herbal Formula-2 (FAHF-2) on peanut allergy
    • Kattan, J. D. et al. Pharmacological and immunological effects of individual herbs in the Food Allergy Herbal Formula-2 (FAHF-2) on peanut allergy. Phytother. Res. 22, 651-659 (2008).
    • (2008) Phytother. Res. , vol.22 , pp. 651-659
    • Kattan, J.D.1
  • 48
    • 24644479841 scopus 로고    scopus 로고
    • Efficacy and tolerability of anti-asthma herbal medicine intervention in adult patients with moderate-severe allergic asthma
    • Wen, M. C. et al. Efficacy and tolerability of anti-asthma herbal medicine intervention in adult patients with moderate-severe allergic asthma. J. Allergy Clin. Immunol. 116, 517-524 (2005).
    • (2005) J. Allergy Clin. Immunol. , vol.116 , pp. 517-524
    • Wen, M.C.1
  • 49
    • 84890365322 scopus 로고    scopus 로고
    • The anti-asthma herbal medicine ASHMI acutely inhibits airway smooth muscle contraction via prostaglandin E2 activation of EP2/EP4 receptors
    • Srivastava, K., Sampson, H. A., Emala, C. W. Sr & Li, X. M. The anti-asthma herbal medicine ASHMI acutely inhibits airway smooth muscle contraction via prostaglandin E2 activation of EP2/EP4 receptors. Am. J. Physiol. Lung Cell Mol. Physiol. 305, 1002-1010 (2013).
    • (2013) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.305 , pp. 1002-1010
    • Srivastava, K.1    Sampson, H.A.2    Emala, C.W.3    Li, X.M.4
  • 50
    • 79960145120 scopus 로고    scopus 로고
    • The anti-asthma Chinese herbal formula ASHMI provides more persistent benefits than dexamethasone in a murine asthma model
    • Srivastava, K. D., Sampson, H. A. & Li, X. The anti-asthma chinese herbal formula ASHMI provides more persistent benefits than dexamethasone in a murine asthma model. J. Allergy Clin. Immunol. 127, AB261 (2011).
    • (2011) J. Allergy Clin. Immunol. , vol.127 , pp. AB261
    • Srivastava, K.D.1    Sampson, H.A.2    Li, X.3
  • 51
    • 84893763163 scopus 로고    scopus 로고
    • The Sophora flavescens flavonoid compound trifolirhizin inhibits acetylcholine induced airway smooth muscle contraction
    • Yang, N. et al. The Sophora flavescens flavonoid compound trifolirhizin inhibits acetylcholine induced airway smooth muscle contraction. Phytochemistry 95, 259-267 (2013).
    • (2013) Phytochemistry , vol.95 , pp. 259-267
    • Yang, N.1
  • 52
    • 84883744125 scopus 로고    scopus 로고
    • Glycyrrhiza uralensis flavonoids present in anti-asthma formula, ASHMI, inhibit memory Th2 responses in vitro and in vivo
    • Yang, N. et al. Glycyrrhiza uralensis flavonoids present in anti-asthma formula, ASHMI, inhibit memory Th2 responses in vitro and in vivo. Phytother. Res. 27, 1381-1391 (2013).
    • (2013) Phytother. Res. , vol.27 , pp. 1381-1391
    • Yang, N.1
  • 53
    • 84937515325 scopus 로고    scopus 로고
    • Ganoderic acid C1 isolated from the anti-asthma formula, ASHMITM suppresses TNF-a production by mouse macrophages and peripheral blood mononuclear cells from asthma patients
    • Liu, C. et al. Ganoderic acid C1 isolated from the anti-asthma formula, ASHMITM suppresses TNF-a production by mouse macrophages and peripheral blood mononuclear cells from asthma patients. Int. Immunopharmacol. 27, 224-231 (2015).
    • (2015) Int. Immunopharmacol. , vol.27 , pp. 224-231
    • Liu, C.1
  • 54
    • 84925866848 scopus 로고    scopus 로고
    • PHY906(KD018), an adjuvant based on a 1800-year-old Chinese medicine, enhanced the anti-tumor activity of Sorafenib by changing the tumor microenvironment
    • Lam, W. et al. PHY906(KD018), an adjuvant based on a 1800-year-old Chinese medicine, enhanced the anti-tumor activity of Sorafenib by changing the tumor microenvironment. Sci. Rep. 5, 9384 (2015).
    • (2015) Sci. Rep. , vol.5 , pp. 9384
    • Lam, W.1
  • 55
    • 77955898834 scopus 로고    scopus 로고
    • The four-herb Chinese medicine PHY906 reduces chemotherapy-induced gastrointestinal toxicity
    • Lam, W. et al. The four-herb Chinese medicine PHY906 reduces chemotherapy-induced gastrointestinal toxicity. Sci. Transl. Med. 2, 45ra59 (2010).
    • (2010) Sci. Transl. Med. , vol.2 , pp. 45ra59
    • Lam, W.1
  • 56
    • 84862776615 scopus 로고    scopus 로고
    • Good practice in reviewing and publishing studies on herbal medicine, with special emphasis on traditional Chinese medicine and Chinese materia medica
    • Chan, K. et al. Good practice in reviewing and publishing studies on herbal medicine, with special emphasis on traditional Chinese medicine and Chinese materia medica. J. Ethnopharmacol. 140, 469-475 (2012).
    • (2012) J. Ethnopharmacol. , vol.140 , pp. 469-475
    • Chan, K.1
  • 57
    • 84943339050 scopus 로고    scopus 로고
    • Compound Danshen dripping pill for treating early diabetic retinopathy: A randomized, double-dummy, double-blind study
    • Luo, D. et al. Compound Danshen dripping pill for treating early diabetic retinopathy: a randomized, double-dummy, double-blind study. eCAM 2015, 539185 (2015).
    • (2015) ECAM , vol.2015 , pp. 539185
    • Luo, D.1
  • 59
    • 84980317985 scopus 로고    scopus 로고
    • A phase IIb trial of coix seed injection for advanced pancreatic cancer
    • Tagliaferri, M. A. et al. A phase IIb trial of coix seed injection for advanced pancreatic cancer. J. Clin. Oncol. 31, e16023 (2013).
    • (2013) J. Clin. Oncol. , vol.31 , pp. e16023
    • Tagliaferri, M.A.1
  • 60
    • 77953922860 scopus 로고    scopus 로고
    • Effect of Fuzheng Huayu formula and its actions against liver fibrosis
    • Liu, C., Hu, Y., Xu, L., Liu, C. & Liu, P. Effect of Fuzheng Huayu formula and its actions against liver fibrosis. Chi. Med. 4, 12 (2009).
    • (2009) Chi. Med. , vol.4 , pp. 12
    • Liu, C.1    Hu, Y.2    Xu, L.3    Liu, C.4    Liu, P.5
  • 61
    • 0042780288 scopus 로고    scopus 로고
    • Psychiatry and the control of dangerousness: On the apotropaic function of the term "mental illness"
    • Szasz, T. Psychiatry and the control of dangerousness: on the apotropaic function of the term "mental illness". J. Med. Ethics 29, 227-230 (2003).
    • (2003) J. Med. Ethics , vol.29 , pp. 227-230
    • Szasz, T.1
  • 63
    • 84980324243 scopus 로고    scopus 로고
    • Withaferin A is a leptin sensitizer with strong antidiabetic properties in mice
    • Lee, J. et al. Withaferin A is a leptin sensitizer with strong antidiabetic properties in mice. Nat. Med. 22, 1023-1032 (2016).
    • (2016) Nat. Med. , vol.22 , pp. 1023-1032
    • Lee, J.1
  • 64
    • 84875621905 scopus 로고    scopus 로고
    • X-ray analysis on the nanogram to microgram scale using porous complexes
    • Inokuma, Y. et al. X-ray analysis on the nanogram to microgram scale using porous complexes. Nature 495, 461-466 (2013).
    • (2013) Nature , vol.495 , pp. 461-466
    • Inokuma, Y.1
  • 65
    • 84948807949 scopus 로고    scopus 로고
    • Engineering of secondary metabolism
    • O'Connor, S. E. Engineering of secondary metabolism. Annu. Rev. Genet. 49, 71-94 (2015).
    • (2015) Annu. Rev. Genet. , vol.49 , pp. 71-94
    • O'Connor, S.E.1
  • 66
    • 84901946024 scopus 로고    scopus 로고
    • Lessons learned from the fate of AstraZeneca's drug pipeline: A five-dimensional framework
    • Cook, D. et al. Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework. Nat. Rev. Drug. Discov. 13, 419-431 (2014).
    • (2014) Nat. Rev. Drug. Discov. , vol.13 , pp. 419-431
    • Cook, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.