Ganoderic acid C1 isolated from the anti-asthma formula, ASHMI™ suppresses TNF-α production by mouse macrophages and peripheral blood mononuclear cells from asthma patients

International Immunopharmacology

Volumn 27, Issue 2, 2015, Pages 224-231

  Liu, Changda ^a   Yang, Nan ^a   Song, Ying ^a   Wang, Lixin ^a,f   Zi, Jiachen ^b   Zhang, Shuwei ^b   Dunkin, David ^a   Busse, Paula ^a   Weir, David ^c   Tversky, Jody ^d   Miller, Rachel L ^e   Goldfarb, Joseph ^a   Zhan, Jixun ^b   Li, Xiu Min ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b Utah State University   (United States)

^c MOUNT SINAI MEDICAL CENTER   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Och Spine at New York Presbyterian Hospitals   (United States)

^f SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

ASHMITM; Asthma; Ganoderic acid C1; Ganoderma lucidum; Inflammation; Macrophages; PBMCs; Peripheral blood mononuclear cells; RAW 264.7 cells; TNF ; Traditional Chinese medicines

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 1; ANTIASTHMATIC AGENT; ANTIINFLAMMATORY AGENT; ASHMI; DICHLOROMETHANE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GANODERENIC ACID A; GANODERENIC ACID D; GANODERIC ACID A; GANODERIC ACID ALPHA; GANODERIC ACID C1; GANODERIC ACID C2; GANODERIC ACID H; GANODERIC ACID J; GANODERIC ACID K; GANODERIC ACID U; GANODERIC ACID V; GANODERIOL F; GANODERMA LUCIDUM EXTRACT; GANOLUCIDIC ACID A; GANOLUCIDIC ACID D; GANOLUCIDIC ACID E; GLYCYRRHIZA URALENSIS EXTRACT; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; SOPHORA FLAVESCENS EXTRACT; TRITERPENOID; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; UNCLASSIFIED DRUG; ASHMI HERBAL FORMULA; GANODERIC ACID; HERBACEOUS AGENT; TRANSCRIPTION FACTOR AP 1; TRITERPENE; TUMOR NECROSIS FACTOR;

ADULT; ANIMAL CELL; ANTIASTHMATIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DOWN REGULATION; DRUG ACTIVITY; DRUG EFFICACY; ETHNOPHARMACOLOGY; FEMALE; GANODERMA LUCIDUM; GLYCYRRHIZA URALENSIS; HERBAL MEDICINE; HUMAN; HUMAN CELL; IMMUNOPHARMACOLOGY; LUNG ALVEOLUS MACROPHAGE; MALE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOPHORA FLAVESCENS; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; CELL CULTURE; CELL LINE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; ISOLATION AND PURIFICATION; MACROPHAGE; METABOLISM; MONONUCLEAR CELL; SOPHORA;

ANIMALS; ANTI-ASTHMATIC AGENTS; APOPTOSIS; ASTHMA; CELL LINE; CELL PROLIFERATION; CELLS, CULTURED; DRUGS, CHINESE HERBAL; FEMALE; GLYCYRRHIZA URALENSIS; HUMANS; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MALE; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; REISHI; SOPHORA; TRANSCRIPTION FACTOR AP-1; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84937515325     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.05.018     Document Type: Article

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