메뉴 건너뛰기




Volumn 120, Issue 24, 2012, Pages 4829-4839

CaMKII γ, a critical regulator of CML stem/progenitor cells, is a target of the natural product berbamine

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BERBAMINE; BETA CATENIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II GAMMA; IMATINIB; STAT3 PROTEIN; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

EID: 84870737638     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-06-434894     Document Type: Article
Times cited : (91)

References (47)
  • 2
    • 0015694748 scopus 로고
    • Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining
    • Rowley JD. Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature. 1973;243(5405):290-293.
    • (1973) Nature , vol.243 , Issue.5405 , pp. 290-293
    • Rowley, J.D.1
  • 3
    • 0034670036 scopus 로고    scopus 로고
    • The molecular biology of chronic myeloid leukemia
    • Deininger MW, Goldman JM, Melo JV. The molecular biology of chronic myeloid leukemia. Blood. 2000;96(10):3343-3356.
    • (2000) Blood , vol.96 , Issue.10 , pp. 3343-3356
    • Deininger, M.W.1    Goldman, J.M.2    Melo, J.V.3
  • 4
    • 65949096301 scopus 로고    scopus 로고
    • The CML stem cell: Evolution of the progenitor
    • Stuart SA, Minami Y, Wang JY. The CML stem cell: evolution of the progenitor. Cell Cycle. 2009;8(9):1338-1343.
    • (2009) Cell Cycle , vol.8 , Issue.9 , pp. 1338-1343
    • Stuart, S.A.1    Minami, Y.2    Wang, J.Y.3
  • 5
    • 38349168416 scopus 로고    scopus 로고
    • Stem cell and kinase activity-independent pathway in resistance of leukaemia to BCR-ABL kinase inhibitors
    • Li S, Li D. Stem cell and kinase activity-independent pathway in resistance of leukaemia to BCR-ABL kinase inhibitors. J Cell Mol Med. 2007;11(6):1251-1262.
    • (2007) J Cell Mol Med , vol.11 , Issue.6 , pp. 1251-1262
    • Li, S.1    Li, D.2
  • 6
    • 42349116071 scopus 로고    scopus 로고
    • Enhanced BCR-ABL kinase inhibition does not result in increased inhibition of downstream signaling pathways or increased growth suppression in CML progenitors
    • DOI 10.1038/sj.leu.2405086, PII 2405086
    • Konig H, Holtz M, Modi H, et al. Enhanced BCR-ABL kinase inhibition does not result in increased inhibition of downstream signaling pathways or increased growth suppression in CML progenitors. Leukemia. 2008;22(4):748-755. (Pubitemid 351552624)
    • (2008) Leukemia , vol.22 , Issue.4 , pp. 748-755
    • Konig, H.1    Holtz, M.2    Modi, H.3    Manley, P.4    Holyoake, T.L.5    Forman, S.J.6    Bhatia, R.7
  • 7
    • 57149098598 scopus 로고    scopus 로고
    • Evidence that resistance to nilotinib
    • may be due to BCR-ABL, Pgp, or Src kinase overexpression.
    • Mahon FX, Hayette S, Lagarde V, et al. Evidence that resistance to nilotinib may be due to BCR-ABL, Pgp, or Src kinase overexpression. Cancer Res. 2008;68(23):9809-9816.
    • (2008) Cancer Res , vol.68 , Issue.23 , pp. 9809-9816
    • Mahon, F.X.1    Hayette, S.2    Lagarde, V.3
  • 8
    • 58249120738 scopus 로고    scopus 로고
    • Beta-Catenin is essential for survival of leukemic stem cells insensitive to kinase inhibition in mice with BCR-ABL-induced chronic myeloid leukemia
    • Hu Y, Chen Y, Douglas L, Li S. beta-Catenin is essential for survival of leukemic stem cells insensitive to kinase inhibition in mice with BCR-ABL-induced chronic myeloid leukemia. Leukemia. 2009;23(1):109-116.
    • (2009) Leukemia , vol.23 , Issue.1 , pp. 109-116
    • Hu, Y.1    Chen, Y.2    Douglas, L.3    Li, S.4
  • 9
    • 68749110580 scopus 로고    scopus 로고
    • Inhibitory effects of omacetaxine on leukemic stem cells and BCR-ABL-induced chronic myeloid leukemia and acute lymphoblastic leukemia in mice
    • Chen Y, Hu Y, Michaels S, Segal D, Brown D, Li S. Inhibitory effects of omacetaxine on leukemic stem cells and BCR-ABL-induced chronic myeloid leukemia and acute lymphoblastic leukemia in mice. Leukemia. 2009;23(8):1446-1454.
    • (2009) Leukemia , vol.23 , Issue.8 , pp. 1446-1454
    • Chen, Y.1    Hu, Y.2    Michaels, S.3    Segal, D.4    Brown, D.5    Li, S.6
  • 10
    • 77950826446 scopus 로고    scopus 로고
    • Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML
    • Zhang XW, Yan XJ, Zhou ZR, et al. Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML. Science. 2010;328(5975):240-243.
    • (2010) Science , vol.328 , Issue.5975 , pp. 240-243
    • Zhang, X.W.1    Yan, X.J.2    Zhou, Z.R.3
  • 11
    • 79951851704 scopus 로고    scopus 로고
    • XPB, a subunit of TFIIH, is a target of the natural product triptolide
    • Titov DV, Gilman B, He QL, et al. XPB, a subunit of TFIIH, is a target of the natural product triptolide. Nat Chem Biol. 2011;7(3):182-188.
    • (2011) Nat Chem Biol , vol.7 , Issue.3 , pp. 182-188
    • Titov, D.V.1    Gilman, B.2    He, Q.L.3
  • 12
    • 0037184696 scopus 로고    scopus 로고
    • A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species
    • DOI 10.1016/S0024-3205(02)02200-2, PII S0024320502022002
    • Kupeli E, Kosar M, Yesilada E, Husnu K, Baser C. A comparative study on the anti-inflammatory, anti-nociceptive and anti-pyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species. Life Sci. 2002;72(6):645-657. (Pubitemid 35441232)
    • (2002) Life Sciences , vol.72 , Issue.6 , pp. 645-657
    • Kupeli, E.1    Kosar, M.2    Yesilada, E.3    Baser, K.H.C.4    Baser, C.5
  • 13
    • 0035950835 scopus 로고    scopus 로고
    • Analytical approaches for traditional chinese medicines exhibiting anti-neoplastic activity
    • Tsai TH. Analytical approaches for traditional chinese medicines exhibiting anti-neoplastic activity. J Chromatogr B Biomed Sci Appl. 2001;764(1-2):27-48.
    • (2001) J Chromatogr B Biomed Sci Appl , vol.764 , Issue.1-2 , pp. 27-48
    • Tsai, T.H.1
  • 14
    • 49049117007 scopus 로고    scopus 로고
    • Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis
    • Ren Y, Lu L, Guo TB, et al. Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis. J Immunol. 2008;181(2):1491-1498.
    • (2008) J Immunol , vol.181 , Issue.2 , pp. 1491-1498
    • Ren, Y.1    Lu, L.2    Guo, T.B.3
  • 15
    • 0026541955 scopus 로고
    • Comparative effects of tetrandrine and berbamine on production of the inflammatory cytokines interleukin-1 and tumor necrosis factor
    • Seow WK, Ferrante A, Summors A, Thong YH. Comparative effects of tetrandrine and berbamine on production of the inflammatory cytokines interleukin-1 and tumor necrosis factor. Life Sci. 1992;50(8):PL53-PL58.
    • (1992) Life Sci , vol.50 , Issue.8
    • Seow, W.K.1    Ferrante, A.2    Summors, A.3    Thong, Y.H.4
  • 16
    • 0036262808 scopus 로고    scopus 로고
    • The effect of calmodulin antagonist berbaminederivative-EBB on hepatoma in vitro and in vivo
    • Liu J, Qi S, Zhu H, Zhang J, Li Z, Wang T. The effect of calmodulin antagonist berbaminederivative-EBB on hepatoma in vitro and in vivo. Chin Med J (Engl). 2002;115(5):759-762. (Pubitemid 34594297)
    • (2002) Chinese Medical Journal , vol.115 , Issue.5 , pp. 759-762
    • Liu, J.1    Qi, S.2    Zhu, H.3    Zhang, J.4    Li, Z.5    Wang, T.6
  • 17
    • 27844611479 scopus 로고    scopus 로고
    • Berbamine: A novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity
    • DOI 10.1016/j.leukres.2005.05.023, PII S0145212605002109
    • Xu R, Dong Q, Yu Y, et al. Berbamine: a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity. Leuk Res. 2006;30(1):17-23. (Pubitemid 41654699)
    • (2006) Leukemia Research , vol.30 , Issue.1 , pp. 17-23
    • Xu, R.1    Dong, Q.2    Yu, Y.3    Zhao, X.4    Gan, X.5    Wu, D.6    Lu, Q.7    Xu, X.8    Yu, X.-F.9
  • 18
    • 67349250886 scopus 로고    scopus 로고
    • Berbamine derivatives: A novel class of compounds for anti-leukemia activity
    • Xie J, Ma T, Gu Y, et al. Berbamine derivatives: a novel class of compounds for anti-leukemia activity. Eur J Med Chem. 2009;44(8):3293-3298.
    • (2009) Eur J Med Chem , vol.44 , Issue.8 , pp. 3293-3298
    • Xie, J.1    Ma, T.2    Gu, Y.3
  • 19
    • 79960463530 scopus 로고    scopus 로고
    • Berbamine inhibits proliferation and induces apoptosis of KU812 cells by increasing Smad3 activity
    • Liang Y, Qiu X, Xu RZ, Zhao XY. Berbamine inhibits proliferation and induces apoptosis of KU812 cells by increasing Smad3 activity. J Zhejiang Univ Sci B. 2011;12(7):568-574.
    • (2011) J Zhejiang Univ Sci B , vol.12 , Issue.7 , pp. 568-574
    • Liang, Y.1    Qiu, X.2    Xu, R.Z.3    Zhao, X.Y.4
  • 20
    • 70249121052 scopus 로고    scopus 로고
    • The anti-proliferation effect of berbamine on k562 resistant cells by inhibiting NF-kappaB pathway
    • Wei YL, Liang Y, Xu L, Zhao XY. The anti-proliferation effect of berbamine on k562 resistant cells by inhibiting NF-kappaB pathway. Anat Rec (Hoboken). 2009;292(7):945-950.
    • (2009) Anat Rec (Hoboken) , vol.292 , Issue.7 , pp. 945-950
    • Wei, Y.L.1    Liang, Y.2    Xu, L.3    Zhao, X.Y.4
  • 21
    • 34248638494 scopus 로고    scopus 로고
    • Berbamine selectively induces apoptosis of human acute promyelocytic leukemia cells via survivin-mediated pathway
    • Zhao XY, He ZW, Wu D, Xu RZ. Berbamine selectively induces apoptosis of human acute promyelocytic leukemia cells via survivin-mediated pathway. Chin Med J (Engl). 2007;120(9):802-806. (Pubitemid 46767828)
    • (2007) Chinese Medical Journal , vol.120 , Issue.9 , pp. 802-806
    • Zhao, X.-Y.1    He, Z.-W.2    Wu, D.3    Xu, R.-Z.4
  • 22
    • 77349098744 scopus 로고    scopus 로고
    • 4-Chlorobenzoyl berbamine induces apoptosis and G2/M cell cycle arrest through the PI3K/Akt and NF-kappaB signal pathway in lymphoma cells
    • Du HP, Shen JK, Yang M, et al. 4-Chlorobenzoyl berbamine induces apoptosis and G2/M cell cycle arrest through the PI3K/Akt and NF-kappaB signal pathway in lymphoma cells. Oncol Rep. 2010;23(3):709-716.
    • (2010) Oncol Rep , vol.23 , Issue.3 , pp. 709-716
    • Du, H.P.1    Shen, J.K.2    Yang, M.3
  • 23
    • 74949124948 scopus 로고    scopus 로고
    • Berbamine, a novel nuclear factor kappaB inhibitor, inhibits growth and induces apoptosis in human myeloma cells
    • Liang Y, Xu RZ, Zhang L, Zhao XY. Berbamine, a novel nuclear factor kappaB inhibitor, inhibits growth and induces apoptosis in human myeloma cells. Acta Pharmacol Sin. 2009;30(12):1659-1665.
    • (2009) Acta Pharmacol Sin , vol.30 , Issue.12 , pp. 1659-1665
    • Liang, Y.1    Xu, R.Z.2    Zhang, L.3    Zhao, X.Y.4
  • 24
    • 77953301389 scopus 로고    scopus 로고
    • A novel calmodulin antagonist O-(4-ethoxyl-butyl)-berbamine overcomes multidrug resistance in drug-resistant MCF-7/ADR breast carcinoma cells
    • Liu R, Zhang Y, Chen Y, et al. A novel calmodulin antagonist O-(4-ethoxyl-butyl)-berbamine overcomes multidrug resistance in drug-resistant MCF-7/ADR breast carcinoma cells. J Pharm Sci. 2010;99(7):3266-3275.
    • (2010) J Pharm Sci , vol.99 , Issue.7 , pp. 3266-3275
    • Liu, R.1    Zhang, Y.2    Chen, Y.3
  • 25
    • 79951678701 scopus 로고    scopus 로고
    • Suppression of human lung cancer cell growth and migration by berbamine
    • Duan H, Luan J, Liu Q, Yagasaki K, Zhang G. Suppression of human lung cancer cell growth and migration by berbamine. Cytotechnology. 2010;62(4):341-348.
    • (2010) Cytotechnology , vol.62 , Issue.4 , pp. 341-348
    • Duan, H.1    Luan, J.2    Liu, Q.3    Yagasaki, K.4    Zhang, G.5
  • 26
    • 65649088963 scopus 로고    scopus 로고
    • Berbamine induces Fas-mediated apoptosis in human hepatocellular carcinoma HepG2 cells and inhibits its tumor growth in nude mice
    • Wang GY, Lv QH, Dong Q, Xu RZ, Dong QH. Berbamine induces Fas-mediated apoptosis in human hepatocellular carcinoma HepG2 cells and inhibits its tumor growth in nude mice. J Asian Nat Prod Res. 2009;11(3):219-228.
    • (2009) J Asian Nat Prod Res , vol.11 , Issue.3 , pp. 219-228
    • Wang, G.Y.1    Lv, Q.H.2    Dong, Q.3    Xu, R.Z.4    Dong, Q.H.5
  • 27
    • 70449669190 scopus 로고    scopus 로고
    • Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action
    • Wang S, Liu Q, Zhang Y, et al. Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action. Mol Cancer. 2009;8:81.
    • (2009) Mol Cancer , vol.8 , pp. 81
    • Wang, S.1    Liu, Q.2    Zhang, Y.3
  • 28
    • 0023021890 scopus 로고
    • A derivative of bisbenzylisoquinoline alkaloid is a new and potential calmodulin antagonist
    • Xu YH, Zhang SP. A derivative of bisbenzylisoquinoline alkaloid is a new and potential calmodulin antagonist. Biochem Biophys Res Commun. 1986;140(1):461-467.
    • (1986) Biochem Biophys Res Commun , vol.140 , Issue.1 , pp. 461-467
    • Xu, Y.H.1    Zhang, S.P.2
  • 29
    • 0242557605 scopus 로고    scopus 로고
    • Effect of E6, a novel calmodulin inhibitor, on activity of P-glycoprotein in purified primary cultured rat brain microvessel endothelial cells
    • Zhu HJ, Liu GQ. Effect of E6, a novel calmodulin inhibitor, on activity of P-glycoprotein in purified primary cultured rat brain microvessel endothelial cells. Acta Pharmacol Sin. 2003;24(11):1143-1149.
    • (2003) Acta Pharmacol Sin , vol.24 , Issue.11 , pp. 1143-1149
    • Zhu, H.J.1    Liu, G.Q.2
  • 30
    • 0028851601 scopus 로고
    • Effect of berbamine on cytosolic phospholipase A2 activation in rabbit platelets
    • Akiba S, Nagatomo R, Ishimoto T, Sato T. Effect of berbamine on cytosolic phospholipase A2 activation in rabbit platelets. Eur J Pharmacol. 1995;291(3):343-350.
    • (1995) Eur J Pharmacol , vol.291 , Issue.3 , pp. 343-350
    • Akiba, S.1    Nagatomo, R.2    Ishimoto, T.3    Sato, T.4
  • 31
    • 0024467339 scopus 로고
    • Benzylisoquinoline compounds inhibit the ability of calmodulin to activate cyclic nucleotide phosphodiesterase
    • Hu ZY, Chen SL, Hao ZG, Huang WL, Peng SX. Benzylisoquinoline compounds inhibit the ability of calmodulin to activate cyclic nucleotide phosphodiesterase. Cell Signal. 1989;1(2):181-185.
    • (1989) Cell Signal , vol.1 , Issue.2 , pp. 181-185
    • Hu, Z.Y.1    Chen, S.L.2    Hao, Z.G.3    Huang, W.L.4    Peng, S.X.5
  • 32
    • 0036312056 scopus 로고    scopus 로고
    • Inhibition of telomerase activity and bcl-2 expression in berbamine-induced apoptosis in HL-60 cells
    • DOI 10.1055/s-2002-32896
    • Ji ZN, Ye WC, Liu GQ, Huang Y. Inhibition of telomerase activity and bcl-2 expression in berbamine-induced apoptosis in HL-60 cells. Planta Med. 2002;68(7):596-600. (Pubitemid 34827923)
    • (2002) Planta Medica , vol.68 , Issue.7 , pp. 596-600
    • Ji, Z.-N.1    Ye, W.-C.2    Liu, G.-Q.3    Huang, Y.4
  • 33
    • 0026774688 scopus 로고
    • Interaction of berbamine compound E6 and calmodulin-dependent myosin light chain kinase
    • Hu ZY, Gong YS, Huang WL. Interaction of berbamine compound E6 and calmodulin-dependent myosin light chain kinase. Biochem Pharmacol. 1992;44(8):1543-1547.
    • (1992) Biochem Pharmacol , vol.44 , Issue.8 , pp. 1543-1547
    • Hu, Z.Y.1    Gong, Y.S.2    Huang, W.L.3
  • 35
    • 78650949272 scopus 로고    scopus 로고
    • Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity
    • Corbin AS, Agarwal A, Loriaux M, Cortes J, Deininger MW, Druker BJ. Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity. J Clin Invest. 2011;121(1):396-409.
    • (2011) J Clin Invest , vol.121 , Issue.1 , pp. 396-409
    • Corbin, A.S.1    Agarwal, A.2    Loriaux, M.3    Cortes, J.4    Deininger, M.W.5    Druker, B.J.6
  • 36
    • 84863124648 scopus 로고    scopus 로고
    • Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival
    • Hamilton A, Helgason GV, Schemionek M, et al. Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival. Blood. 2012;119(6):1501-1510.
    • (2012) Blood , vol.119 , Issue.6 , pp. 1501-1510
    • Hamilton, A.1    Helgason, G.V.2    Schemionek, M.3
  • 37
    • 0035886024 scopus 로고    scopus 로고
    • Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells
    • Guzman ML, Neering SJ, Upchurch D, et al. Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood. 2001;98(8):2301-2307.
    • (2001) Blood , vol.98 , Issue.8 , pp. 2301-2307
    • Guzman, M.L.1    Neering, S.J.2    Upchurch, D.3
  • 38
    • 0035929612 scopus 로고    scopus 로고
    • Calmodulin-dependent kinase II mediates T cell receptor/CD3- And phorbol ester-induced activation of IkappaB kinase
    • Hughes K, Edin S, Antonsson A, Grundstrom T. Calmodulin-dependent kinase II mediates T cell receptor/CD3- and phorbol ester-induced activation of IkappaB kinase. J Biol Chem. 2001;276(38):36008-36013.
    • (2001) J Biol Chem , vol.276 , Issue.38 , pp. 36008-36013
    • Hughes, K.1    Edin, S.2    Antonsson, A.3    Grundstrom, T.4
  • 39
    • 45549108898 scopus 로고    scopus 로고
    • Activated Ca2+/calmodulindependent protein kinase IIgamma is a critical regulator of myeloid leukemia cell proliferation
    • Si J, Collins SJ. Activated Ca2+/calmodulindependent protein kinase IIgamma is a critical regulator of myeloid leukemia cell proliferation. Cancer Res. 2008;68(10):3733-3742.
    • (2008) Cancer Res , vol.68 , Issue.10 , pp. 3733-3742
    • Si, J.1    Collins, S.J.2
  • 40
    • 70350212688 scopus 로고    scopus 로고
    • Targeted disruption of stat3 reveals a major role for follicular stem cells in skin tumor initiation
    • Kim DJ, Kataoka K, Rao D, Kiguchi K, Cotsarelis G, Digiovanni J. Targeted disruption of stat3 reveals a major role for follicular stem cells in skin tumor initiation. Cancer Res. 2009;69(19):7587-7594.
    • (2009) Cancer Res , vol.69 , Issue.19 , pp. 7587-7594
    • Kim, D.J.1    Kataoka, K.2    Rao, D.3    Kiguchi, K.4    Cotsarelis, G.5    Digiovanni, J.6
  • 41
    • 70350212976 scopus 로고    scopus 로고
    • STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells
    • Sherry MM, Reeves A, Wu JK, Cochran BH. STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells. Stem Cells. 2009;27(10):2383-2392.
    • (2009) Stem Cells , vol.27 , Issue.10 , pp. 2383-2392
    • Sherry, M.M.1    Reeves, A.2    Wu, J.K.3    Cochran, B.H.4
  • 42
    • 67349251942 scopus 로고
    • Isolation of the Alkaloids, Berberine and Berbamine, from Mahonia Swaseyi
    • Greathouse GA, Rigler NE. Isolation of the Alkaloids, Berberine and Berbamine, from Mahonia Swaseyi. Plant Physiol. 1940;15(3):563-564.
    • (1940) Plant Physiol , vol.15 , Issue.3 , pp. 563-564
    • Greathouse, G.A.1    Rigler, N.E.2
  • 43
    • 34248183417 scopus 로고    scopus 로고
    • CaMKII regulates retinoic acid receptor transcriptional activity and the differentiation of myeloid leukemia cells
    • DOI 10.1172/JCI30779
    • Si J, Mueller L, Collins SJ. CaMKII regulates retinoic acid receptor transcriptional activity and the differentiation of myeloid leukemia cells. J Clin Invest. 2007;117(5):1412-1421. (Pubitemid 46718429)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1412-1421
    • Si, J.1    Mueller, L.2    Collins, S.J.3
  • 44
    • 34547956876 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent kinase activity is required for efficient induction of osteoclast differentiation and bone resorption by receptor activator of nuclear factor kappa B ligand (RANKL)
    • DOI 10.1002/jcp.21076
    • Ang ES, Zhang P, Steer JH, et al. Calcium/calmodulindependent kinase activity is required for efficient induction of osteoclast differentiation and bone resorption by receptor activator of nuclear factor kappa B ligand (RANKL). J Cell Physiol. 2007;212(3):787-795. (Pubitemid 47267548)
    • (2007) Journal of Cellular Physiology , vol.212 , Issue.3 , pp. 787-795
    • Ang, E.S.M.1    Zhang, P.2    Steer, J.H.3    Tan, J.W.-Y.4    Yip, K.5    Zheng, M.H.6    Joyce, D.A.7    Xu, J.8
  • 45
    • 25444526102 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II is essential for extracellular signal-regulated kinase-mediated signaling in differentiated smooth muscle cells
    • DOI 10.1161/01.RES.0000182630.29093.0d
    • Marganski WA, Gangopadhyay SS, Je HD, Gallant C, Morgan KG. Targeting of a novel Ca+2/calmodulin-dependent protein kinase II is essential for extracellular signal-regulated kinase-mediated signaling in differentiated smooth muscle cells. Circ Res. 2005;97(6):541-549. (Pubitemid 41361744)
    • (2005) Circulation Research , vol.97 , Issue.6 , pp. 541-549
    • Marganski, W.A.1    Gangopadhyay, S.S.2    Je, H.-D.3    Gallant, C.4    Morgan, K.G.5
  • 46
    • 68549118671 scopus 로고    scopus 로고
    • CaMKII knockdown attenuates H2O2-induced phosphorylation of ERK1/2, PKB/Akt, and IGF-1R in vascular smooth muscle cells
    • Bouallegue A, Pandey NR, Srivastava AK. CaMKII knockdown attenuates H2O2-induced phosphorylation of ERK1/2, PKB/Akt, and IGF-1R in vascular smooth muscle cells. Free Radic Biol Med. 2009;47(6):858-866.
    • (2009) Free Radic Biol Med , vol.47 , Issue.6 , pp. 858-866
    • Bouallegue, A.1    Pandey, N.R.2    Srivastava, A.K.3
  • 47
    • 65949117537 scopus 로고
    • Determination of berbamine in rat plasma by reversed phase high performance liquid chromatography
    • Li BX, Gao YD, Li WH. Determination of berbamine in rat plasma by reversed phase high performance liquid chromatography. J Harbin Med Univ. 1995;29(3):201-203.
    • (1995) J Harbin Med Univ , vol.29 , Issue.3 , pp. 201-203
    • Li, B.X.1    Gao, Y.D.2    Li, W.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.