Drug-induced amino acid deprivation as strategy for cancer therapy

Journal of Hematology and Oncology

Volumn 10, Issue 1, 2017, Pages

  Fung, Marcus Kwong Lam ^a   Chan, Godfrey Chi Fung ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Amino acid starvation; Arginine; Asparagine; Cancer treatment; Glutamine

Indexed keywords

ARGININE; ASPARAGINASE; ASPARAGINE; BIS 2 (5 PHENYLACETAMIDO 1,3,4 THIADIAZOL 2 YL)ETHYL SULFIDE NANOPARTICLE; CHLOROQUINE; ENZYME INHIBITOR; GEMCITABINE; GLUTAMINASE INHIBITOR; GLUTAMINE; NANOPARTICLE; PEGARGIMINASE; PEGYLATED ARGINASE 1; TEMOZOLOMIDE; UNCLASSIFIED DRUG; VINCRISTINE; AMINO ACID; ANTINEOPLASTIC AGENT;

ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE MYELOID LEUKEMIA; ACUTE PANCREATITIS; ALLERGY; AMINO ACID METABOLISM; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER CELL; CANCER COMBINATION CHEMOTHERAPY; CANCER RESISTANCE; CANCER THERAPY; CELL DEATH; CELL PROLIFERATION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG HALF LIFE; DRUG POTENTIATION; ENZYME SPECIFICITY; GLIOBLASTOMA; HEMATOLOGIC MALIGNANCY; HEPATITIS; HUMAN; HYPERSENSITIVITY; IMMUNOSUPPRESSIVE TREATMENT; KWASHIORKOR; LIVER CELL CARCINOMA; LYMPHOMA; LYMPHOSARCOMA; MELANOMA; MESENCHYMAL STROMA CELL; MESOTHELIOMA; MOLECULAR BIOLOGY; NEUROTOXICITY; NONHUMAN; PANCREAS CANCER; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PRACTICE GUIDELINE; PROSTATE CANCER; PROTEIN PROCESSING; REVIEW; THROMBOSIS; TREATMENT INDICATION; METABOLISM; NEOPLASM;

AMINO ACIDS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ARGININE; ASPARAGINASE; GLUTAMINE; HUMANS; NEOPLASMS;

EID: 85026227277     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/s13045-017-0509-9     Document Type: Review

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