-
1
-
-
33749478922
-
Cancer's molecular sweet tooth and the Warburg effect
-
Kim JW, Dang CV (2006) Cancer's molecular sweet tooth and the Warburg effect. Cancer Res 66(18):8927-8930.
-
(2006)
Cancer Res
, vol.66
, Issue.18
, pp. 8927-8930
-
-
Kim, J.W.1
Dang, C.V.2
-
2
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB (2009) Understanding the Warburg effect: The metabolic requirements of cell proliferation. Science 324(5930):1029-1033.
-
(2009)
Science
, vol.324
, Issue.5930
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
3
-
-
76249110471
-
Rethinking the Warburg effect with Myc micromanaging glutamine metabolism
-
Dang CV (2010) Rethinking the Warburg effect with Myc micromanaging glutamine metabolism. Cancer Res 70(3):859-862.
-
(2010)
Cancer Res
, vol.70
, Issue.3
, pp. 859-862
-
-
Dang, C.V.1
-
4
-
-
45549107064
-
Arginine deprivation as a targeted therapy for cancer
-
Feun L, et al. (2008) Arginine deprivation as a targeted therapy for cancer. Curr Pharm Des 14(11):1049-1057.
-
(2008)
Curr Pharm des
, vol.14
, Issue.11
, pp. 1049-1057
-
-
Feun, L.1
-
5
-
-
84869507054
-
Arginine deprivation as a new treatment strategy for head and neck cancer
-
Huang CC, et al. (2012) Arginine deprivation as a new treatment strategy for head and neck cancer. Oral Oncol 48(12):1227-1235.
-
(2012)
Oral Oncol
, vol.48
, Issue.12
, pp. 1227-1235
-
-
Huang, C.C.1
-
6
-
-
0032145202
-
Use of L-asparaginase in childhood ALL
-
Müller HJ, Boos J (1998) Use of L-asparaginase in childhood ALL. Crit Rev Oncol Hematol 28(2):97-113.
-
(1998)
Crit Rev Oncol Hematol
, vol.28
, Issue.2
, pp. 97-113
-
-
Müller, H.J.1
Boos, J.2
-
7
-
-
80051923932
-
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
-
Possemato R, et al. (2011) Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature 476(7360):346-350.
-
(2011)
Nature
, vol.476
, Issue.7360
, pp. 346-350
-
-
Possemato, R.1
-
8
-
-
0041976909
-
Arginine deprivation, growth inhibition and tumour cell death: 3. Deficient utilisation of citrulline by malignant cells
-
Wheatley DN, Campbell E (2003) Arginine deprivation, growth inhibition and tumour cell death: 3. Deficient utilisation of citrulline by malignant cells. Br J Cancer 89(3): 573-576.
-
(2003)
Br J Cancer
, vol.89
, Issue.3
, pp. 573-576
-
-
Wheatley, D.N.1
Campbell, E.2
-
9
-
-
77955281020
-
Glutamine addiction: A new therapeutic target in cancer
-
Wise DR, Thompson CB (2010) Glutamine addiction: A new therapeutic target in cancer. Trends Biochem Sci 35(8):427-433.
-
(2010)
Trends Biochem Sci
, vol.35
, Issue.8
, pp. 427-433
-
-
Wise, D.R.1
Thompson, C.B.2
-
10
-
-
32944469353
-
Pegylated arginine deiminase treatment of patients with metastatic melanoma: Results from phase i and II studies
-
Ascierto PA, et al. (2005) Pegylated arginine deiminase treatment of patients with metastatic melanoma: Results from phase I and II studies. J Clin Oncol 23(30): 7660-7668.
-
(2005)
J Clin Oncol
, vol.23
, Issue.30
, pp. 7660-7668
-
-
Ascierto, P.A.1
-
11
-
-
34248325307
-
Effective asparagine depletion with pegylated asparaginase results in improved outcomes in adult acute lymphoblastic leukemia: Cancer and Leukemia Group B Study 9511
-
Wetzler M, et al. (2007) Effective asparagine depletion with pegylated asparaginase results in improved outcomes in adult acute lymphoblastic leukemia: Cancer and Leukemia Group B Study 9511. Blood 109(10):4164-4167.
-
(2007)
Blood
, vol.109
, Issue.10
, pp. 4164-4167
-
-
Wetzler, M.1
-
12
-
-
0342748603
-
Arginine deiminase inhibits proliferation of human leukemia cells more potently than asparaginase by inducing cell cycle arrest and apoptosis
-
Gong H, Zölzer F, von Recklinghausen G, Havers W, Schweigerer L (2000) Arginine deiminase inhibits proliferation of human leukemia cells more potently than asparaginase by inducing cell cycle arrest and apoptosis. Leukemia 14(5):826-829.
-
(2000)
Leukemia
, vol.14
, Issue.5
, pp. 826-829
-
-
Gong, H.1
Zölzer, F.2
Von Recklinghausen, G.3
Havers, W.4
Schweigerer, L.5
-
13
-
-
0036792124
-
Pegylated arginine deiminase (ADI-SS PEG20,000 mw) inhibits human melanomas and hepatocellular carcinomas in vitro and in vivo
-
Ensor CM, Holtsberg FW, Bomalaski JS, Clark MA (2002) Pegylated arginine deiminase (ADI-SS PEG20,000 mw) inhibits human melanomas and hepatocellular carcinomas in vitro and in vivo. Cancer Res 62(19):5443-5450.
-
(2002)
Cancer Res
, vol.62
, Issue.19
, pp. 5443-5450
-
-
Ensor, C.M.1
Holtsberg, F.W.2
Bomalaski, J.S.3
Clark, M.A.4
-
14
-
-
51949087021
-
Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase
-
Bowles TL, et al. (2008) Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase. Int J Cancer 123(8):1950-1955.
-
(2008)
Int J Cancer
, vol.123
, Issue.8
, pp. 1950-1955
-
-
Bowles, T.L.1
-
15
-
-
77949735952
-
Reduced argininosuccinate synthetase is a predictive biomarker for the development of pulmonary metastasis in patients with osteosarcoma
-
Kobayashi E, et al. (2010) Reduced argininosuccinate synthetase is a predictive biomarker for the development of pulmonary metastasis in patients with osteosarcoma. Mol Cancer Ther 9(3):535-544.
-
(2010)
Mol Cancer Ther
, vol.9
, Issue.3
, pp. 535-544
-
-
Kobayashi, E.1
-
16
-
-
84862187475
-
Deprivation of arginine by recombinant human arginase in prostate cancer cells
-
Hsueh EC, et al. (2012) Deprivation of arginine by recombinant human arginase in prostate cancer cells. J Hematol Oncol 5:17.
-
(2012)
J Hematol Oncol
, vol.5
, pp. 17
-
-
Hsueh, E.C.1
-
17
-
-
84856458783
-
Arginine deiminase PEG20 inhibits growth of small cell lung cancers lacking expression of argininosuccinate synthetase
-
Kelly MP, et al. (2012) Arginine deiminase PEG20 inhibits growth of small cell lung cancers lacking expression of argininosuccinate synthetase. Br J Cancer 106(2): 324-332.
-
(2012)
Br J Cancer
, vol.106
, Issue.2
, pp. 324-332
-
-
Kelly, M.P.1
-
18
-
-
58349098150
-
Arginine deiminase as a novel therapy for prostate cancer induces autophagy and caspase-independent apoptosis
-
Kim RH, et al. (2009) Arginine deiminase as a novel therapy for prostate cancer induces autophagy and caspase-independent apoptosis. Cancer Res 69(2):700-708.
-
(2009)
Cancer Res
, vol.69
, Issue.2
, pp. 700-708
-
-
Kim, R.H.1
-
19
-
-
66349091716
-
ADI, autophagy and apoptosis: Metabolic stress as a therapeutic option for prostate cancer
-
Kim RH, Bold RJ, Kung HJ (2009) ADI, autophagy and apoptosis: Metabolic stress as a therapeutic option for prostate cancer. Autophagy 5(4):567-568.
-
(2009)
Autophagy
, vol.5
, Issue.4
, pp. 567-568
-
-
Kim, R.H.1
Bold, R.J.2
Kung, H.J.3
-
20
-
-
84867238654
-
Autophagy: Resetting glutamine-dependent metabolism and oxygen consumption
-
Lin TC, et al. (2012) Autophagy: Resetting glutamine-dependent metabolism and oxygen consumption. Autophagy 8(10):1477-1493.
-
(2012)
Autophagy
, vol.8
, Issue.10
, pp. 1477-1493
-
-
Lin, T.C.1
-
21
-
-
84872184647
-
Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma
-
Syed N, et al. (2013) Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma. Cell Death Dis 4:e458.
-
(2013)
Cell Death Dis
, vol.4
, pp. e458
-
-
Syed, N.1
-
22
-
-
18744390391
-
Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis
-
Shchepina LA, et al. (2002) Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis. Oncogene 21(53):8149-8157.
-
(2002)
Oncogene
, vol.21
, Issue.53
, pp. 8149-8157
-
-
Shchepina, L.A.1
-
23
-
-
33749433230
-
Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation
-
Brennan JP, et al. (2006) Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation. Cardiovasc Res 72(2):313-321.
-
(2006)
Cardiovasc Res
, vol.72
, Issue.2
, pp. 313-321
-
-
Brennan, J.P.1
-
24
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Yue Z, Jin S, Yang C, Levine AJ, Heintz N (2003) Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci USA 100(25):15077-15082.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.25
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
25
-
-
20144381544
-
Essential roles of Atg5 and FADD in autophagic cell death: Dissection of autophagic cell death into vacuole formation and cell death
-
Pyo JO, et al. (2005) Essential roles of Atg5 and FADD in autophagic cell death: Dissection of autophagic cell death into vacuole formation and cell death. J Biol Chem 280(21):20722-20729.
-
(2005)
J Biol Chem
, vol.280
, Issue.21
, pp. 20722-20729
-
-
Pyo, J.O.1
-
26
-
-
34248203863
-
Structure of Atg5.Atg16, a complex essential for autophagy
-
Matsushita M, et al. (2007) Structure of Atg5.Atg16, a complex essential for autophagy. J Biol Chem 282(9):6763-6772.
-
(2007)
J Biol Chem
, vol.282
, Issue.9
, pp. 6763-6772
-
-
Matsushita, M.1
-
27
-
-
79952628267
-
The Beclin 1 network regulates autophagy and apoptosis
-
Kang R, Zeh HJ, Lotze MT, Tang D (2011) The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 18(4):571-580.
-
(2011)
Cell Death Differ
, vol.18
, Issue.4
, pp. 571-580
-
-
Kang, R.1
Zeh, H.J.2
Lotze, M.T.3
Tang, D.4
-
28
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
Klionsky DJ, et al. (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8(4):445-544.
-
(2012)
Autophagy
, vol.8
, Issue.4
, pp. 445-544
-
-
Klionsky, D.J.1
-
29
-
-
84904421955
-
Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells
-
Qiu F, et al. (2014) Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells. Sci Signal 7(319):ra31.
-
(2014)
Sci Signal
, vol.7
, Issue.319
, pp. ra31
-
-
Qiu, F.1
-
30
-
-
33846429217
-
Pegylated recombinant human arginase (rhArg-peg5,000mw) inhibits the in vitro and in vivo proliferation of human hepatocellular carcinoma through arginine depletion
-
Cheng PNM, et al. (2007) Pegylated recombinant human arginase (rhArg-peg5,000mw) inhibits the in vitro and in vivo proliferation of human hepatocellular carcinoma through arginine depletion. Cancer Res 67(1):309-317.
-
(2007)
Cancer Res
, vol.67
, Issue.1
, pp. 309-317
-
-
Cheng, P.N.M.1
-
31
-
-
46849121421
-
Utilizing flow cytometry to monitor autophagy in living mammalian cells
-
Shvets E, Fass E, Elazar Z (2008) Utilizing flow cytometry to monitor autophagy in living mammalian cells. Autophagy 4(5):621-628.
-
(2008)
Autophagy
, vol.4
, Issue.5
, pp. 621-628
-
-
Shvets, E.1
Fass, E.2
Elazar, Z.3
-
32
-
-
69449083200
-
Autophagic degradation of nuclear components in mammalian cells
-
Park YE, et al. (2009) Autophagic degradation of nuclear components in mammalian cells. Autophagy 5(6):795-804.
-
(2009)
Autophagy
, vol.5
, Issue.6
, pp. 795-804
-
-
Park, Y.E.1
-
33
-
-
84855712059
-
Autophagic removal of micronuclei
-
Rello-Varona S, et al. (2012) Autophagic removal of micronuclei. Cell Cycle 11(1): 170-176.
-
(2012)
Cell Cycle
, vol.11
, Issue.1
, pp. 170-176
-
-
Rello-Varona, S.1
-
34
-
-
84882938509
-
Direct uptake and degradation of DNA by lysosomes
-
Fujiwara Y, et al. (2013) Direct uptake and degradation of DNA by lysosomes. Autophagy 9(8):1167-1171.
-
(2013)
Autophagy
, vol.9
, Issue.8
, pp. 1167-1171
-
-
Fujiwara, Y.1
-
35
-
-
0038107749
-
Microtubule network facilitates targeting of human cytomegalovirus capsid
-
Ogawa-Goto K, et al. (2003) Microtubule network facilitates targeting of human cytomegalovirus capsid. J Virol 77(15):8451-8547.
-
(2003)
J Virol
, vol.77
, Issue.15
, pp. 8451-8547
-
-
Ogawa-Goto, K.1
|