Anti-leukemic mechanisms of pegylated arginase i in acute lymphoblastic T-cell leukemia

Leukemia

Volumn 27, Issue 3, 2013, Pages 569-577

  Morrow, K ^a   Hernandez, C P ^a   Raber, P ^a   Del Valle, L ^a   Wilk, A M ^a   Majumdar, S ^a   Wyczechowska, D ^a   Reiss, K ^a   Rodriguez, P C ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

arginase; arginine starvation; pegylated arginase; T ALL

Indexed keywords

ANTINEOPLASTIC AGENT; GENERAL CONTROL NONREPRESSED 2 KINASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 34; INITIATION FACTOR 2ALPHA; PEGYLATED ARGINASE I; PKR LIKE ENDOPLASMIC RETICULUM RELATED KINASE; PROTEIN SERINE THREONINE KINASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CHEMOSENSITIVITY; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RECEPTOR DOWN REGULATION; TUMOR XENOGRAFT;

ANIMALS; APOPTOSIS; ARGINASE; BLOTTING, WESTERN; CELL PROLIFERATION; EIF-2 KINASE; EUKARYOTIC INITIATION FACTOR-2; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MICE; MICE, INBRED NOD; MICE, SCID; PHOSPHORYLATION; POLYETHYLENE GLYCOLS; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEIN PHOSPHATASE 1; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SURVIVAL RATE;

EID: 84875220307     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2012.247     Document Type: Article

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