Modeling the evolution of SIV sooty mangabey progenitor virus towards HIV-2 using humanized mice

Virology

Volumn 510, Issue , 2017, Pages 175-184

  Schmitt, Kimberly ^a   Mohan Kumar, Dipu ^a   Curlin, James ^a   Remling Mulder, Leila ^a   Stenglein, Mark ^a   O'Connor, Shelby ^b   Marx, Preston ^c,d   Akkina, Ramesh ^a  

^a Veterinary Dentistry and Oral Surgery   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c Tulane School of Public Health and Tropical Medicine   (United States)

^d TULANE NATIONAL PRIMATE RESEARCH CENTER   (United States)

Author keywords

Cross species viral transmission; Modeling SIV evolution into HIV in humanized mice; Origin of human pathogens in NHP; SIV genetic changes towards HIV 2; SIV pathogenesis in humanized mice; SIVsm evolution into HIV 2 lineage; Viral adaptive changes and genetic evolution

Indexed keywords

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; ENVELOPE GENE; GENETIC ANALYSIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 2; MOLECULAR EVOLUTION; MOUSE; NEF GENE; NONHUMAN; PRIORITY JOURNAL; REV GENE; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; T CELL DEPLETION; VIREMIA; VIRUS GENE; VIRUS LOAD; VIRUS TRANSMISSION; ANIMAL; BIOLOGICAL MODEL; CD4 LYMPHOCYTE COUNT; CERCOCEBUS ATYS; GENETICS; GROWTH, DEVELOPMENT AND AGING; SCID MOUSE; SIMIAN IMMUNODEFICIENCY VIRUS; VIROLOGY; VIRUS CULTURE;

VIRAL PROTEIN;

AMINO ACID SUBSTITUTION; ANIMALS; CD4 LYMPHOCYTE COUNT; CERCOCEBUS ATYS; EVOLUTION, MOLECULAR; HIV-2; HUMANS; MICE; MICE, SCID; MODELS, BIOLOGICAL; SERIAL PASSAGE; SIMIAN IMMUNODEFICIENCY VIRUS; VIRAL LOAD; VIRAL PROTEINS;

EID: 85025624889     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2017.07.005     Document Type: Article

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