-
1
-
-
0025743306
-
Importance of the nef gene for maintenance of high viral loads and for development of AIDS
-
Kestler H., Ringler D.J., Mori K., Panicali D.L., Sehgal P.K., Daniel M.D., and Desrosiers R.C. Importance of the nef gene for maintenance of high viral loads and for development of AIDS. Cell 65 (1991) 651-662
-
(1991)
Cell
, vol.65
, pp. 651-662
-
-
Kestler, H.1
Ringler, D.J.2
Mori, K.3
Panicali, D.L.4
Sehgal, P.K.5
Daniel, M.D.6
Desrosiers, R.C.7
-
2
-
-
0027220174
-
HIV induces thymus depletion in vivo
-
Bonyhadi M.L., Rabin L., Salimi S., Brown D.A., Kosek J., McCune J.M., and Kaneshima H. HIV induces thymus depletion in vivo. Nature 363 (1993) 728-732
-
(1993)
Nature
, vol.363
, pp. 728-732
-
-
Bonyhadi, M.L.1
Rabin, L.2
Salimi, S.3
Brown, D.A.4
Kosek, J.5
McCune, J.M.6
Kaneshima, H.7
-
3
-
-
0032538278
-
Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice
-
Hanna Z., Kay D.G., Rebai N., Guimond A., Jothy S., and Jolicoeur P. Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice. Cell 95 (1998) 163-175
-
(1998)
Cell
, vol.95
, pp. 163-175
-
-
Hanna, Z.1
Kay, D.G.2
Rebai, N.3
Guimond, A.4
Jothy, S.5
Jolicoeur, P.6
-
4
-
-
0028804160
-
Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients
-
Deacon N.J., Tsykin A., Solomon A., Smith K., Ludford-Menting M., Hooker D.J., et al. Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients. Science 270 (1995) 988-991
-
(1995)
Science
, vol.270
, pp. 988-991
-
-
Deacon, N.J.1
Tsykin, A.2
Solomon, A.3
Smith, K.4
Ludford-Menting, M.5
Hooker, D.J.6
-
5
-
-
0028835788
-
Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection
-
Kirchhoff F., Greenough T.C., Brettler D.B., Sullivan J.L., and Desrosiers R.C. Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection. N. Engl. J. Med. 332 (1995) 228-232
-
(1995)
N. Engl. J. Med.
, vol.332
, pp. 228-232
-
-
Kirchhoff, F.1
Greenough, T.C.2
Brettler, D.B.3
Sullivan, J.L.4
Desrosiers, R.C.5
-
6
-
-
0030788298
-
A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 Nef alleles in lymphocyte activation
-
Alexander L., Du Z., Rosenzweig M., Jung J.U., and Desrosiers R.C. A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 Nef alleles in lymphocyte activation. J. Virol. 71 (1997) 6094-6099
-
(1997)
J. Virol.
, vol.71
, pp. 6094-6099
-
-
Alexander, L.1
Du, Z.2
Rosenzweig, M.3
Jung, J.U.4
Desrosiers, R.C.5
-
7
-
-
0036230879
-
Live and let die: Nef functions beyond HIV replication
-
Fackler O.T., and Baur A.S. Live and let die: Nef functions beyond HIV replication. Immunity 16 (2002) 493-497
-
(2002)
Immunity
, vol.16
, pp. 493-497
-
-
Fackler, O.T.1
Baur, A.S.2
-
8
-
-
0034948709
-
Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators
-
Simmons A., Aluvihare V., and McMichael A. Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators. Immunity 14 (2001) 763-777
-
(2001)
Immunity
, vol.14
, pp. 763-777
-
-
Simmons, A.1
Aluvihare, V.2
McMichael, A.3
-
9
-
-
0028485232
-
HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization
-
Baur A.S., Sawai E.T., Dazin P., Fantl W.J., Cheng-Mayer C., and Peterlin B.M. HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization. Immunity 1 (1994) 373-384
-
(1994)
Immunity
, vol.1
, pp. 373-384
-
-
Baur, A.S.1
Sawai, E.T.2
Dazin, P.3
Fantl, W.J.4
Cheng-Mayer, C.5
Peterlin, B.M.6
-
10
-
-
0031039979
-
Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling
-
Iafrate A.J., Bronson S., and Skowronski J. Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling. EMBO J. 16 (1997) 673-684
-
(1997)
EMBO J.
, vol.16
, pp. 673-684
-
-
Iafrate, A.J.1
Bronson, S.2
Skowronski, J.3
-
12
-
-
0030835321
-
Pseudotyping human immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin A
-
Aiken C. Pseudotyping human immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin A. J. Virol. 71 (1997) 5871-5877
-
(1997)
J. Virol.
, vol.71
, pp. 5871-5877
-
-
Aiken, C.1
-
13
-
-
0028302998
-
Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene
-
Chowers M.Y., Spina C.A., Kwoh T.J., Fitch N.J., Richman D.D., and Guatelli J.C. Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene. J. Virol. 68 (1994) 2906-2914
-
(1994)
J. Virol.
, vol.68
, pp. 2906-2914
-
-
Chowers, M.Y.1
Spina, C.A.2
Kwoh, T.J.3
Fitch, N.J.4
Richman, D.D.5
Guatelli, J.C.6
-
14
-
-
0028006247
-
The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages
-
Miller M.D., Warmerdam M.T., Gaston I., Greene W.C., and Feinberg M.B. The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. J. Exp. Med. 179 (1994) 101-113
-
(1994)
J. Exp. Med.
, vol.179
, pp. 101-113
-
-
Miller, M.D.1
Warmerdam, M.T.2
Gaston, I.3
Greene, W.C.4
Feinberg, M.B.5
-
15
-
-
0028924785
-
Human immunodeficiency virus type 1 Nef induces accumulation of CD4 in early endosomes
-
Schwartz O., Dautry-Varsat A., Goud B., Marechal V., Subtil A., Heard J.M., and Danos O. Human immunodeficiency virus type 1 Nef induces accumulation of CD4 in early endosomes. J. Virol. 69 (1995) 528-533
-
(1995)
J. Virol.
, vol.69
, pp. 528-533
-
-
Schwartz, O.1
Dautry-Varsat, A.2
Goud, B.3
Marechal, V.4
Subtil, A.5
Heard, J.M.6
Danos, O.7
-
16
-
-
0037074008
-
HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway
-
Blagoveshchenskaya A.D., Thomas L., Feliciangeli S.F., Hung C.H., and Thomas G. HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway. Cell 111 (2002) 853-866
-
(2002)
Cell
, vol.111
, pp. 853-866
-
-
Blagoveshchenskaya, A.D.1
Thomas, L.2
Feliciangeli, S.F.3
Hung, C.H.4
Thomas, G.5
-
17
-
-
34147169409
-
HIV-1 Nef assembles a Src family kinase-ZAP-70/Syk-PI3K cascade to downregulate cell-surface MHC-I
-
Hung C.H., Thomas L., Ruby C.E., Atkins K.M., Morris N.P., Knight Z.A., et al. HIV-1 Nef assembles a Src family kinase-ZAP-70/Syk-PI3K cascade to downregulate cell-surface MHC-I. Cell Host Microbe 1 (2007) 121-133
-
(2007)
Cell Host Microbe
, vol.1
, pp. 121-133
-
-
Hung, C.H.1
Thomas, L.2
Ruby, C.E.3
Atkins, K.M.4
Morris, N.P.5
Knight, Z.A.6
-
18
-
-
0035051976
-
Living in oblivion: HIV immune evasion
-
Piguet V., and Trono D. Living in oblivion: HIV immune evasion. Semin. Immunol. 13 (2001) 51-57
-
(2001)
Semin. Immunol.
, vol.13
, pp. 51-57
-
-
Piguet, V.1
Trono, D.2
-
19
-
-
0032556872
-
HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes
-
Collins K.L., Chen B.K., Kalams S.A., Walker B.D., and Baltimore D. HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. Nature 391 (1998) 397-401
-
(1998)
Nature
, vol.391
, pp. 397-401
-
-
Collins, K.L.1
Chen, B.K.2
Kalams, S.A.3
Walker, B.D.4
Baltimore, D.5
-
20
-
-
0027209701
-
Nef from primary isolates of human immunodeficiency virus type 1 suppresses surface CD4 expression in human and mouse T cells
-
Anderson S., Shugars D.C., Swanstrom R., and Garcia J.V. Nef from primary isolates of human immunodeficiency virus type 1 suppresses surface CD4 expression in human and mouse T cells. J. Virol. 67 (1993) 4923-4931
-
(1993)
J. Virol.
, vol.67
, pp. 4923-4931
-
-
Anderson, S.1
Shugars, D.C.2
Swanstrom, R.3
Garcia, J.V.4
-
21
-
-
0027158904
-
Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection
-
Benson R.E., Sanfridson A., Ottinger J.S., Doyle C., and Cullen B.R. Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection. J. Exp. Med. 177 (1993) 1561-1566
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1561-1566
-
-
Benson, R.E.1
Sanfridson, A.2
Ottinger, J.S.3
Doyle, C.4
Cullen, B.R.5
-
22
-
-
0025733252
-
Serine phosphorylation-independent downregulation of cell-surface CD4 by nef
-
Garcia J.V., and Miller A.D. Serine phosphorylation-independent downregulation of cell-surface CD4 by nef. Nature 350 (1991) 508-511
-
(1991)
Nature
, vol.350
, pp. 508-511
-
-
Garcia, J.V.1
Miller, A.D.2
-
23
-
-
0027315870
-
CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals
-
Mariani R., and Skowronski J. CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals. Proc. Natl Acad. Sci. USA 90 (1993) 5549-5553
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 5549-5553
-
-
Mariani, R.1
Skowronski, J.2
-
24
-
-
0033578072
-
Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner
-
Lama J., Mangasarian A., and Trono D. Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner. Curr. Biol. 9 (1999) 622-631
-
(1999)
Curr. Biol.
, vol.9
, pp. 622-631
-
-
Lama, J.1
Mangasarian, A.2
Trono, D.3
-
25
-
-
0033578016
-
Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein
-
Ross T.M., Oran A.E., and Cullen B.R. Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein. Curr. Biol. 9 (1999) 613-621
-
(1999)
Curr. Biol.
, vol.9
, pp. 613-621
-
-
Ross, T.M.1
Oran, A.E.2
Cullen, B.R.3
-
26
-
-
0037127303
-
Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells
-
Cortes M.J., Wong-Staal F., and Lama J. Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells. J. Biol. Chem. 277 (2002) 1770-1779
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1770-1779
-
-
Cortes, M.J.1
Wong-Staal, F.2
Lama, J.3
-
27
-
-
0026786630
-
High level of surface CD4 prevents stable human immunodeficiency virus infection of T-cell transfectants
-
Marshall W.L., Diamond D.C., Kowalski M.M., and Finberg R.W. High level of surface CD4 prevents stable human immunodeficiency virus infection of T-cell transfectants. J. Virol. 66 (1992) 5492-5499
-
(1992)
J. Virol.
, vol.66
, pp. 5492-5499
-
-
Marshall, W.L.1
Diamond, D.C.2
Kowalski, M.M.3
Finberg, R.W.4
-
28
-
-
18844363668
-
Biology of the HIV Nef protein
-
Das S.R., and Jameel S. Biology of the HIV Nef protein. Indian J. Med. Res. 121 (2005) 315-332
-
(2005)
Indian J. Med. Res.
, vol.121
, pp. 315-332
-
-
Das, S.R.1
Jameel, S.2
-
30
-
-
0029015330
-
Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis
-
Aiken C., and Trono D. Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis. J. Virol. 69 (1995) 5048-5056
-
(1995)
J. Virol.
, vol.69
, pp. 5048-5056
-
-
Aiken, C.1
Trono, D.2
-
31
-
-
0031572847
-
The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling
-
Arold S., Franken P., Strub M.P., Hoh F., Benichou S., Benarous R., and Dumas C. The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling. Structure 5 (1997) 1361-1372
-
(1997)
Structure
, vol.5
, pp. 1361-1372
-
-
Arold, S.1
Franken, P.2
Strub, M.P.3
Hoh, F.4
Benichou, S.5
Benarous, R.6
Dumas, C.7
-
32
-
-
0034894379
-
Structure-function relationships in HIV-1 Nef
-
Geyer M., Fackler O.T., and Peterlin B.M. Structure-function relationships in HIV-1 Nef. EMBO Rep. 2 (2001) 580-585
-
(2001)
EMBO Rep.
, vol.2
, pp. 580-585
-
-
Geyer, M.1
Fackler, O.T.2
Peterlin, B.M.3
-
33
-
-
0343494918
-
Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain
-
Lee C.-H., Saksela K., Mirza U.A., Chait B.T., and Kuriyan J. Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain. Cell 85 (1996) 931-942
-
(1996)
Cell
, vol.85
, pp. 931-942
-
-
Lee, C.-H.1
Saksela, K.2
Mirza, U.A.3
Chait, B.T.4
Kuriyan, J.5
-
34
-
-
19244382596
-
Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions
-
Liu L.X., Heveker N., Fackler O.T., Arold S., Le Gall S., Janvier K., et al. Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions. J. Virol. 74 (2000) 5310-5319
-
(2000)
J. Virol.
, vol.74
, pp. 5310-5319
-
-
Liu, L.X.1
Heveker, N.2
Fackler, O.T.3
Arold, S.4
Le Gall, S.5
Janvier, K.6
-
35
-
-
10644261241
-
Human immunodeficiency virus type 1 Nef domains required for disruption of major histocompatibility complex class I trafficking are also necessary for coprecipitation of Nef with HLA-A2
-
Williams M., Roeth J.F., Kasper M.R., Filzen T.M., and Collins K.L. Human immunodeficiency virus type 1 Nef domains required for disruption of major histocompatibility complex class I trafficking are also necessary for coprecipitation of Nef with HLA-A2. J. Virol. 79 (2005) 632-636
-
(2005)
J. Virol.
, vol.79
, pp. 632-636
-
-
Williams, M.1
Roeth, J.F.2
Kasper, M.R.3
Filzen, T.M.4
Collins, K.L.5
-
36
-
-
10844282788
-
Oligomerization is required for HIV-1 Nef-induced activation of the Src family protein-tyrosine kinase, Hck
-
Ye H., Choi H.J., Poe J., and Smithgall T.E. Oligomerization is required for HIV-1 Nef-induced activation of the Src family protein-tyrosine kinase, Hck. Biochemistry 43 (2004) 15775-15784
-
(2004)
Biochemistry
, vol.43
, pp. 15775-15784
-
-
Ye, H.1
Choi, H.J.2
Poe, J.3
Smithgall, T.E.4
-
37
-
-
6344276677
-
Conserved residues in the HIV-1 Nef hydrophobic pocket are essential for recruitment and activation of the Hck tyrosine kinase
-
Choi H.J., and Smithgall T.E. Conserved residues in the HIV-1 Nef hydrophobic pocket are essential for recruitment and activation of the Hck tyrosine kinase. J. Mol. Biol. 343 (2004) 1255-1268
-
(2004)
J. Mol. Biol.
, vol.343
, pp. 1255-1268
-
-
Choi, H.J.1
Smithgall, T.E.2
-
38
-
-
33644861986
-
Identification of new fluorescent protein fragments for bimolecular fluorescence complementation analysis under physiological conditions
-
Shyu Y.J., Liu H., Deng X., and Hu C.D. Identification of new fluorescent protein fragments for bimolecular fluorescence complementation analysis under physiological conditions. BioTechniques 40 (2006) 61-66
-
(2006)
BioTechniques
, vol.40
, pp. 61-66
-
-
Shyu, Y.J.1
Liu, H.2
Deng, X.3
Hu, C.D.4
-
39
-
-
33144469859
-
Biochemical indication for myristoylation-dependent conformational changes in HIV-1 Nef
-
Breuer S., Gerlach H., Kolaric B., Urbanke C., Opitz N., and Geyer M. Biochemical indication for myristoylation-dependent conformational changes in HIV-1 Nef. Biochemistry 45 (2006) 2339-2349
-
(2006)
Biochemistry
, vol.45
, pp. 2339-2349
-
-
Breuer, S.1
Gerlach, H.2
Kolaric, B.3
Urbanke, C.4
Opitz, N.5
Geyer, M.6
-
40
-
-
0035844009
-
Domain assembly, surface accessibility and sequence conservation in full length HIV-1 Nef
-
Geyer M., and Peterlin B.M. Domain assembly, surface accessibility and sequence conservation in full length HIV-1 Nef. FEBS Lett. 496 (2001) 91-95
-
(2001)
FEBS Lett.
, vol.496
, pp. 91-95
-
-
Geyer, M.1
Peterlin, B.M.2
-
41
-
-
0032553012
-
RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef
-
Arold S., O'Brien R., Franken P., Strub M.P., Hoh F., Dumas C., and Ladbury J.E. RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef. Biochemistry 37 (1998) 14683-14691
-
(1998)
Biochemistry
, vol.37
, pp. 14683-14691
-
-
Arold, S.1
O'Brien, R.2
Franken, P.3
Strub, M.P.4
Hoh, F.5
Dumas, C.6
Ladbury, J.E.7
-
42
-
-
0029881450
-
The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase
-
Grzesiek S., Bax A., Clore G.M., Gronenborn A.M., Hu J.-S., Kaufman J., et al. The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase. Nat. Struct. Biol. 3 (1996) 340-345
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 340-345
-
-
Grzesiek, S.1
Bax, A.2
Clore, G.M.3
Gronenborn, A.M.4
Hu, J.-S.5
Kaufman, J.6
-
43
-
-
0033776709
-
HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes
-
Piguet V., Wan L., Borel C., Mangasarian A., Demaurex N., Thomas G., and Trono D. HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes. Nat. Cell Biol. 2 (2000) 163-167
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 163-167
-
-
Piguet, V.1
Wan, L.2
Borel, C.3
Mangasarian, A.4
Demaurex, N.5
Thomas, G.6
Trono, D.7
-
44
-
-
0036889125
-
Direct binding of human immunodeficiency virus type 1 Nef to the major histocompatibility complex class I (MHC-I) cytoplasmic tail disrupts MHC-I trafficking
-
Williams M., Roeth J.F., Kasper M.R., Fleis R.I., Przybycin C.G., and Collins K.L. Direct binding of human immunodeficiency virus type 1 Nef to the major histocompatibility complex class I (MHC-I) cytoplasmic tail disrupts MHC-I trafficking. J. Virol. 76 (2002) 12173-12184
-
(2002)
J. Virol.
, vol.76
, pp. 12173-12184
-
-
Williams, M.1
Roeth, J.F.2
Kasper, M.R.3
Fleis, R.I.4
Przybycin, C.G.5
Collins, K.L.6
-
45
-
-
33644584737
-
Role of myristoylation and N-terminal basic residues in membrane association of the human immunodeficiency virus type 1 Nef protein
-
Bentham M., Mazaleyrat S., and Harris M. Role of myristoylation and N-terminal basic residues in membrane association of the human immunodeficiency virus type 1 Nef protein. J. Gen. Virol. 87 (2006) 563-571
-
(2006)
J. Gen. Virol.
, vol.87
, pp. 563-571
-
-
Bentham, M.1
Mazaleyrat, S.2
Harris, M.3
-
46
-
-
0028805516
-
A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein
-
Lee C.-H., Leung B., Lemmon M.A., Zheng J., Cowburn D., Kuriyan J., and Saksela K. A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein. EMBO J. 14 (1995) 5006-5015
-
(1995)
EMBO J.
, vol.14
, pp. 5006-5015
-
-
Lee, C.-H.1
Leung, B.2
Lemmon, M.A.3
Zheng, J.4
Cowburn, D.5
Kuriyan, J.6
Saksela, K.7
-
47
-
-
0035907306
-
The tyrosine kinase Hck is an inhibitor of HIV-1 replication counteracted by the viral vif protein
-
Hassaine G., Courcoul M., Bessou G., Barthalay Y., Picard C., Olive D., et al. The tyrosine kinase Hck is an inhibitor of HIV-1 replication counteracted by the viral vif protein. J. Biol. Chem. 276 (2001) 16885-16893
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16885-16893
-
-
Hassaine, G.1
Courcoul, M.2
Bessou, G.3
Barthalay, Y.4
Picard, C.5
Olive, D.6
-
48
-
-
0037160057
-
Activation of Stat3 by the Src family kinase Hck requires a functional SH3 domain
-
Schreiner S.J., Schiavone A.P., and Smithgall T.E. Activation of Stat3 by the Src family kinase Hck requires a functional SH3 domain. J. Biol. Chem. 277 (2002) 45680-45687
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45680-45687
-
-
Schreiner, S.J.1
Schiavone, A.P.2
Smithgall, T.E.3
-
49
-
-
0034795885
-
CD4 down-modulation by human immunodeficiency virus type 1 Nef correlates with the efficiency of viral replication and with CD4(+) T-cell depletion in human lymphoid tissue ex vivo
-
Glushakova S., Munch J., Carl S., Greenough T.C., Sullivan J.L., Margolis L., and Kirchhoff F. CD4 down-modulation by human immunodeficiency virus type 1 Nef correlates with the efficiency of viral replication and with CD4(+) T-cell depletion in human lymphoid tissue ex vivo. J. Virol. 75 (2001) 10113-10117
-
(2001)
J. Virol.
, vol.75
, pp. 10113-10117
-
-
Glushakova, S.1
Munch, J.2
Carl, S.3
Greenough, T.C.4
Sullivan, J.L.5
Margolis, L.6
Kirchhoff, F.7
-
50
-
-
0036231461
-
Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes
-
Lundquist C.A., Tobiume M., Zhou J., Unutmaz D., and Aiken C. Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes. J. Virol. 76 (2002) 4625-4633
-
(2002)
J. Virol.
, vol.76
, pp. 4625-4633
-
-
Lundquist, C.A.1
Tobiume, M.2
Zhou, J.3
Unutmaz, D.4
Aiken, C.5
-
51
-
-
67649410579
-
Inhibition of HIV-1 infection and replication by enhancing viral incorporation of innate anti-HIV-1 protein A3G: a non-pathogenic Nef mutant-based anti-HIV strategy
-
Green L.A., Liu Y., and He J.J. Inhibition of HIV-1 infection and replication by enhancing viral incorporation of innate anti-HIV-1 protein A3G: a non-pathogenic Nef mutant-based anti-HIV strategy. J. Biol. Chem. 284 (2009) 13363-13372
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 13363-13372
-
-
Green, L.A.1
Liu, Y.2
He, J.J.3
-
52
-
-
0034820906
-
HIV type 1 chemokine receptor usage in mother-to-child transmission
-
Salvatori F., and Scarlatti G. HIV type 1 chemokine receptor usage in mother-to-child transmission. AIDS Res. Hum. Retroviruses 17 (2001) 925-935
-
(2001)
AIDS Res. Hum. Retroviruses
, vol.17
, pp. 925-935
-
-
Salvatori, F.1
Scarlatti, G.2
-
53
-
-
0031936306
-
Neutralization sensitivity of human immunodeficiency virus type 1 primary isolates to antibodies and CD4-based reagents is independent of coreceptor usage
-
Trkola A., Ketas T., Kewalramani V.N., Endorf F., Binley J.M., Katinger H., et al. Neutralization sensitivity of human immunodeficiency virus type 1 primary isolates to antibodies and CD4-based reagents is independent of coreceptor usage. J. Virol. 72 (1998) 1876-1885
-
(1998)
J. Virol.
, vol.72
, pp. 1876-1885
-
-
Trkola, A.1
Ketas, T.2
Kewalramani, V.N.3
Endorf, F.4
Binley, J.M.5
Katinger, H.6
-
54
-
-
7044239645
-
Detection of protein-protein interactions in plants using bimolecular fluorescence complementation
-
Bracha-Drori K., Shichrur K., Katz A., Oliva M., Angelovici R., Yalovsky S., and Ohad N. Detection of protein-protein interactions in plants using bimolecular fluorescence complementation. Plant J. 40 (2004) 419-427
-
(2004)
Plant J.
, vol.40
, pp. 419-427
-
-
Bracha-Drori, K.1
Shichrur, K.2
Katz, A.3
Oliva, M.4
Angelovici, R.5
Yalovsky, S.6
Ohad, N.7
-
55
-
-
2942559261
-
Visualization of Myc/Max/Mad family dimers and the competition for dimerization in living cells
-
Grinberg A.V., Hu C.D., and Kerppola T.K. Visualization of Myc/Max/Mad family dimers and the competition for dimerization in living cells. Mol. Cell. Biol. 24 (2004) 4294-4308
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 4294-4308
-
-
Grinberg, A.V.1
Hu, C.D.2
Kerppola, T.K.3
-
56
-
-
3142766112
-
Visualization of G protein betagamma dimers using bimolecular fluorescence complementation demonstrates roles for both beta and gamma in subcellular targeting
-
Hynes T.R., Tang L., Mervine S.M., Sabo J.L., Yost E.A., Devreotes P.N., and Berlot C.H. Visualization of G protein betagamma dimers using bimolecular fluorescence complementation demonstrates roles for both beta and gamma in subcellular targeting. J. Biol. Chem. 279 (2004) 30279-30286
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 30279-30286
-
-
Hynes, T.R.1
Tang, L.2
Mervine, S.M.3
Sabo, J.L.4
Yost, E.A.5
Devreotes, P.N.6
Berlot, C.H.7
-
57
-
-
34247525991
-
Detection of transient protein-protein interactions by bimolecular fluorescence complementation: the Abl-SH3 case
-
Morell M., Espargaro A., Aviles F.X., and Ventura S. Detection of transient protein-protein interactions by bimolecular fluorescence complementation: the Abl-SH3 case. Proteomics 7 (2007) 1023-1036
-
(2007)
Proteomics
, vol.7
, pp. 1023-1036
-
-
Morell, M.1
Espargaro, A.2
Aviles, F.X.3
Ventura, S.4
-
58
-
-
13244266915
-
Myristoyl moiety of HIV Nef is involved in regulation of the interaction with calmodulin in vivo
-
Matsubara M., Jing T., Kawamura K., Shimojo N., Titani K., Hashimoto K., and Hayashi N. Myristoyl moiety of HIV Nef is involved in regulation of the interaction with calmodulin in vivo. Protein Sci. 14 (2005) 494-503
-
(2005)
Protein Sci.
, vol.14
, pp. 494-503
-
-
Matsubara, M.1
Jing, T.2
Kawamura, K.3
Shimojo, N.4
Titani, K.5
Hashimoto, K.6
Hayashi, N.7
-
59
-
-
0034602776
-
The Nef protein of HIV-1 associates with rafts and primes T cells for activation
-
Wang J.K., Kiyokawa E., Verdin E., and Trono D. The Nef protein of HIV-1 associates with rafts and primes T cells for activation. Proc. Natl Acad. Sci. USA 97 (2000) 394-399
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 394-399
-
-
Wang, J.K.1
Kiyokawa, E.2
Verdin, E.3
Trono, D.4
-
60
-
-
0033917035
-
Characterization and molecular basis of the oligomeric structure of HIV-1 nef protein
-
Arold S., Hoh F., Domergue S., Birck C., Delsuc M.A., Jullien M., and Dumas C. Characterization and molecular basis of the oligomeric structure of HIV-1 nef protein. Protein Sci. 9 (2000) 1137-1148
-
(2000)
Protein Sci.
, vol.9
, pp. 1137-1148
-
-
Arold, S.1
Hoh, F.2
Domergue, S.3
Birck, C.4
Delsuc, M.A.5
Jullien, M.6
Dumas, C.7
-
61
-
-
0029962938
-
Physical and functional interaction of Nef with Lck-HIV-1 Nef-induced T-cell signaling defects
-
Collette Y., Dutartre H., Benziane A., Ramos-Morales F., Benarous R., Harris M., and Olive D. Physical and functional interaction of Nef with Lck-HIV-1 Nef-induced T-cell signaling defects. J. Biol. Chem. 271 (1996) 6333-6341
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6333-6341
-
-
Collette, Y.1
Dutartre, H.2
Benziane, A.3
Ramos-Morales, F.4
Benarous, R.5
Harris, M.6
Olive, D.7
-
62
-
-
0034134113
-
Interactions of HIV-1 NEF with cellular signal transducing proteins
-
Renkema G.H., and Saksela K. Interactions of HIV-1 NEF with cellular signal transducing proteins. Front. Biosci. 5 (2000) D268-D283
-
(2000)
Front. Biosci.
, vol.5
-
-
Renkema, G.H.1
Saksela, K.2
-
63
-
-
0033153464
-
Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
-
Fackler O.T., Luo W., Geyer M., Alberts A.S., and Peterlin B.M. Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Mol. Cell 3 (1999) 729-739
-
(1999)
Mol. Cell
, vol.3
, pp. 729-739
-
-
Fackler, O.T.1
Luo, W.2
Geyer, M.3
Alberts, A.S.4
Peterlin, B.M.5
-
64
-
-
0029064101
-
A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity
-
Sawai E.T., Baur A.S., Peterlin B.M., Levy J.A., and Cheng-Mayer C. A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity. J. Biol. Chem. 270 (1995) 15307-15314
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15307-15314
-
-
Sawai, E.T.1
Baur, A.S.2
Peterlin, B.M.3
Levy, J.A.4
Cheng-Mayer, C.5
-
65
-
-
0036241055
-
Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation
-
Hu C.D., Chinenov Y., and Kerppola T.K. Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation. Mol. Cell 9 (2002) 789-798
-
(2002)
Mol. Cell
, vol.9
, pp. 789-798
-
-
Hu, C.D.1
Chinenov, Y.2
Kerppola, T.K.3
-
66
-
-
33750321026
-
Nef alleles from human immunodeficiency virus type 1-infected long-term-nonprogressor hemophiliacs with or without late disease progression are defective in enhancing virus replication and CD4 down-regulation
-
Crotti A., Neri F., Corti D., Ghezzi S., Heltai S., Baur A., et al. Nef alleles from human immunodeficiency virus type 1-infected long-term-nonprogressor hemophiliacs with or without late disease progression are defective in enhancing virus replication and CD4 down-regulation. J. Virol. 80 (2006) 10663-10674
-
(2006)
J. Virol.
, vol.80
, pp. 10663-10674
-
-
Crotti, A.1
Neri, F.2
Corti, D.3
Ghezzi, S.4
Heltai, S.5
Baur, A.6
-
67
-
-
33746322762
-
Functional characterization of HIV-1 Nef mutants in the context of viral infection
-
Fackler O.T., Moris A., Tibroni N., Giese S.I., Glass B., Schwartz O., and Krausslich H.G. Functional characterization of HIV-1 Nef mutants in the context of viral infection. Virology 351 (2006) 322-339
-
(2006)
Virology
, vol.351
, pp. 322-339
-
-
Fackler, O.T.1
Moris, A.2
Tibroni, N.3
Giese, S.I.4
Glass, B.5
Schwartz, O.6
Krausslich, H.G.7
-
68
-
-
0035816584
-
HIV-1 Nef promotes survival of myeloid cells by a Stat3-dependent pathway
-
Briggs S.D., Scholtz B., Jacque J.M., Swingler S., Stevenson M., and Smithgall T.E. HIV-1 Nef promotes survival of myeloid cells by a Stat3-dependent pathway. J. Biol. Chem. 276 (2001) 25605-25611
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25605-25611
-
-
Briggs, S.D.1
Scholtz, B.2
Jacque, J.M.3
Swingler, S.4
Stevenson, M.5
Smithgall, T.E.6
-
69
-
-
48049095013
-
Bimolecular fluorescence complementation (BiFC) analysis of protein interactions in Caenorhabditis elegans
-
Hiatt S.M., Shyu Y.J., Duren H.M., and Hu C.D. Bimolecular fluorescence complementation (BiFC) analysis of protein interactions in Caenorhabditis elegans. Methods 45 (2008) 185-191
-
(2008)
Methods
, vol.45
, pp. 185-191
-
-
Hiatt, S.M.1
Shyu, Y.J.2
Duren, H.M.3
Hu, C.D.4
-
70
-
-
0025959660
-
BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias
-
Muller A.J., Young J.C., Pendergast A.M., Pondel M., Landau R.N., Littman D.R., and Witte O.N. BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias. Mol. Cell. Biol. 11 (1991) 1785-1792
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 1785-1792
-
-
Muller, A.J.1
Young, J.C.2
Pendergast, A.M.3
Pondel, M.4
Landau, R.N.5
Littman, D.R.6
Witte, O.N.7
-
71
-
-
35348957280
-
Allosteric loss-of-function mutations in HIV-1 Nef from a long-term non-progressor
-
Trible R.P., Emert-Sedlak L., Wales T.E., Ayyavoo V., Engen J.R., and Smithgall T.E. Allosteric loss-of-function mutations in HIV-1 Nef from a long-term non-progressor. J. Mol. Biol. 374 (2007) 121-129
-
(2007)
J. Mol. Biol.
, vol.374
, pp. 121-129
-
-
Trible, R.P.1
Emert-Sedlak, L.2
Wales, T.E.3
Ayyavoo, V.4
Engen, J.R.5
Smithgall, T.E.6
|