bcl-2 expression facilitates human immunodeficiency virus type 1-mediated cytopathic effects during acute spreading infections

Journal of Virology

Volumn 70, Issue 7, 1996, Pages 4617-4622

  Sandstrom, Paul A ^a   Pardi, Diane ^a   Goldsmith, Cynthia S ^a   Chengying, Duan ^a   Diamond, Alan M ^b   Folks, Thomas M ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; ONCOPROTEIN; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CELL VIABILITY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; SYNCYTIUM; VIRUS IMMUNITY; VIRUS INFECTIVITY; VIRUS TRANSMISSION; CELL CULTURE; CELL LINE; CYTOPATHOGENIC EFFECT; GENE EXPRESSION; GENETICS; GIANT CELL; PATHOGENICITY; PHYSIOLOGY; VIROLOGY;

CELL LINE; CYTOPATHOGENIC EFFECT, VIRAL; GENE EXPRESSION; GIANT CELLS; HIV-1; HUMANS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED;

EID: 0029665761     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.7.4617-4622.1996     Document Type: Article

References (32)

1. Ameisen, J. C., J. Estaquier, and T. Idziorek. 1995. From AIDS to parasite infection: pathogen-mediated subversion of programmed celi death as a mechanism for immune dysregulation. Immunol. Rev. 142:9-53.
2. Antoni, B. A., P. Sabbatini, A. B. Rabson, and E. White. 1995. Inhibition of apoptosis in human immunodeficiency virus-infected cells enhances virus production and facilitates persistent infection. J. Virol. 69:2384-2392.
3. Buyd, J. M., S. Malstrom, T. Subramanian, L. K. Venkatesh, U. Schaeper, B. Elangovan, C. D'Sa-eipper, and G. Chinnadurai. 1994. Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. Cell 79:341-351.
4. Coffin, J. M. 1995. HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. Science 267:483-489.
5. 4a.Diamond, A. M., and P. A. Sandstrom. Unpublished observations.
6. Elliott, L. H., T. G. Ksiazek, P. E. Rollin, C. F. Spiropoulou, S. Morzunov, M. Monroe, C. S. Goldsmith, C. D. Humphrey, S. R. Zaki, J. W. Krebs, G. Maupin, K. Gage, J. E. Childs, S. T. Nichol, and C. J. Peters. 1994. Isolation of the causative agent of Hantavirus pulmonary syndrome. Am. J. Trop. Med. Hyg. 51:102-108.
7. Fernandez-Sarabia, M. J., and J. R. Bischof. 1993. Bcl-2 associates with the ras-related protein R-ras p23. Nature (London) 366:274-275.
8. Folks, T. M., S. Benn, A. Rabson, T. Theodore, M. D. Hoggan, M. Martin, M. Lightfoote, and K. Sell. 1985. Characterization of a continuous T-cell line susceptible to the cytopathic effects of the acquired immunodeficiency syndrome (AIDS)-associated retrovirus. Proc. Natl. Acad. Sci. USA 82:4539-4543.
9. Folks, T. M., D. Powell, M. Lightfoote, A. S. Fauci, S. Benn, A. Rabson, D. Daugherty, H. E. Gendelman, M. D. Hoggan, S. Venkatesan, and M. Martin. 1986. Biological and biochemical characterization of a cloned Leu-3 cell surviving infection with the acquired immune deficiency syndrome retrovirus. J. Exp. Med. 164:280-290.
10. Hinshaw, V. S., C. W. Olsen, N. Dybdahl-Sissoko, and D. Evans. 1994. Apoptosis: a mechanism of cell killing by influenza A and B viruses. J. Virol. 68:3667-3673.
11. Ho, D. D., A. U. Neumann, A. S. Perelson, W. Chen, J. M. Leonard, and M. Markowitz. 1995. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature (London) 373:123-126.
12. Hockenbery, D. M., Z. N. Oltvai, X.-M. Yin, C. L. Milliman, and S. J. Korsmeyer. 1993. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75:241-251.
13. Hockenbery, D. M., M. Zutter, W. Hickey, M. Nahm, and S. J. Korsmeyer. 1991. Bcl-2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc. Natl. Acad. Sci. USA 88:6961-6965.
14. Kane, D. J., T. A. Sarafian, R. Anton, H. Hahn, E. Butler Gralla, J. Selverstone Valentine, T. Ord, and D. E. Bredesen. 1993. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science 262:1274-1277.
15. Levine, B., Q. Huang, J. T. Isaacs, J. C. Reed, D. E. Griffin, and J. M. Hardwick. 1993. Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene. Nature (London) 361:739-742.
16. Levy, J. A. 1995. HIV research: a need to focus on the right target. Lancet 345:1619-1621.
17. Li, C. J., D. J. Friedman, C. Wang, V. Metelev, and A. B. Pardee. 1995. Induction of apoptosis in uninfected lymphocytes by HIV-1 tat protein. Science 268:429-431.
18. Nunez, G., R. Merino, D. Grillot, and M. Gonzalez-Garcia. 1994. Bcl-2 and Bcl-x: regulatory switches for lymphoid death and survival. Immunol. Today 15:582-588.
19. Oltvai, Z. N., C. L. Milliman, and S. J. Korsmeyer. 1993. Bcl-2 heterodimerizes in vivo with a conserved homolog. Bax, that accelerates programmed cell death. Cell 74:609-619.
20. + T lymphocytes genetically deficient in LFA-1: LFA-1 is required for HIV-mediated cell fusion but not for viral transmission. J. Exp. Med. 173:511-514.
21. Phillips, D. M. 1994. The role of cell-to-cell transmission in HIV infection. AIDS 8:719-731.
22. Sandslrom, P. A., D. Pardi, P. W. Tebby, R. W. Dudek, D. M. Terrian, T. M. Folks, and T. M. Buttke. 1995. Lipid hydroperoxide-induced apoptosis: lack of inhibition by bcl-2 overexpression. FEBS Lett. 365:66-70.
23. Sato, H., J. Orenstein, D. Dimitrov, and M. Martin. 1992. Cell-to-cell spread of HIV-1 occurs within minutes and may not involve the participation of virus particles. Virology 186:712-724.
24. Smith, S. D., M. Shatsky, P. S. Cohen, R. Warnke, M. P. Link, and B. E. Glader. 1984. Monoclonal antibody and enzymatic profiles of human malignant T-lymphuid cells and derived cell lines. Cancer Res. 44:5657-5660.
25. Strasser, A., A. W. Harris, and S. Cory. 1991. bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 67:889-899.
26. Takayama, S., T. Sato, S. Krajewski, K. Kochel, S. Irie, J. A. Millan, and J. C. Reed. 1995. Cloning and functional analysis of BAG-1: a novel bcl-2-binding protein with anti-cell death activity. Cell 80:279-284.
27. Vaux, D. L., G. Haecker, and A. Strasser. 1994. An evolutionary perspective on apoptosis. Cell 76:777-779.
28. Vermot-Desroches, C., D. Riagal, R. S. Escaich, J. Bernaud, C. Pichoud, J.-P. Lamelin, and C. Trepo. 1991. Functional epitope analysis of the human CD11a/CD18 molecule (LFA-1, lymphocyte function-associated antigen 1) involved in HIV-1-induced syncytium formation. Scand. J. Immunol. 34:461-470.
29. Wei, X., S. K. Ghosh, M. E. Taylor, V. A. Johnson, E. A. Emini, P. Deutsch, J. D. Lifson, S. Bonhoeffer, M. A. Nowak, B. H. Hahn, M. S. Saag, and G. M. Shaw. 1995. Viral dynamics in human immunodeficiency virus type 1 infection. Nature (London) 373:117-122.
30. Willey, R. L., D. H. Smith, L. A. Lasky, T. S. Theodore, P. L. Earl, B. Moss, D. J. Capon, and M. A. Martin. 1988. In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity. J. Virol. 62:139-147.
31. L and Bcl-2, displaces Bax and promotes cell death. Cell 80:285-291.
32. Zauli, G., D. Gibellini, D. Milani, M. Mazzoni, P. Borgalti, M. La Placa, and S. Capitani. 1993. Human immunodeficiency virus type 1 tat protein protects lymphoid, epithelial, and neuronal cell lines from death by apoptosis. Cancer Res. 53:4481-4485.