Fractionation and identification of antioxidant peptides from an enzymatically hydrolysed Palmaria palmata protein isolate

Food Research International

Volumn 100, Issue , 2017, Pages 416-422

  Harnedy, Pádraigín A ^a   O'Keeffe, Martina B ^a   FitzGerald, Richard J ^a  

^a UNIVERSITY OF LIMERICK   (Ireland)

Author keywords

Antioxidant; Antioxidant peptide; Bioactive peptide; Food protein hydrolysates; Palmaria palmata; Peptide identification; Simulated gastrointestinal digestion

Indexed keywords

ANTIOXIDANTS; FOOD PRESERVATIVES; HYDROLYSIS; PEPTIDES;

ANTIOXIDANT PEPTIDES; BIOACTIVE PEPTIDES; FOOD PROTEINS; GASTROINTESTINAL DIGESTION; PALMARIA PALMATA; PEPTIDE IDENTIFICATION;

PROTEINS;

ANTIOXIDANT; PEPTIDE; PLANT EXTRACT; PLANT PROTEIN;

BIOLOGICAL MODEL; CHEMISTRY; DIGESTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; ISOLATION AND PURIFICATION; RED ALGA;

ANTIOXIDANTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIGESTION; HYDROLYSIS; MODELS, BIOLOGICAL; PEPTIDES; PLANT EXTRACTS; PLANT PROTEINS; RHODOPHYTA;

EID: 85025163723     PISSN: 09639969     EISSN: 18737145     Source Type: Journal    
DOI: 10.1016/j.foodres.2017.07.037     Document Type: Article

References (32)

1. Beaulieu, L., Sirois, M., Tamigneaux, E., Evaluation of the in vitro biological activity of protein hydrolysates of the edible red alga, Palmaria palmata (dulse) harvested from the Gaspe coast and cultivated in tanks. Journal of Applied Phycology 28:5 (2016), 3101–3115.
2. Bondu, S., Bonnet, C., Gaubert, J., Deslandes, É., Turgeon, S., Beaulieu, L., Bioassay-guided fractionation approach for determination of protein precursors of proteolytic bioactive metabolites from macroalgae. Journal of Applied Phycology 27:5 (2014), 2059–2074.
3. Chen, H., Zhao, M., Lin, L., Wang, J., Sun-Waterhouse, D., Donga, Y., Su, G., Identification of antioxidative peptides from defatted walnut meal hydrolysate with potential for improving learning and memory. Food Research International 78 (2015), 216–223.
4. Dávalos, A., Miguel, M., Bartolomé, B., López-Fandiño, R., Antioxidant activity of peptides derived from egg white proteins by enzymatic hydrolysis. Journal of Food Protection 67:9 (2004), 1939–1944.
5. Freitas, A.C., Andrade, J.C., Silva, F.M., Rocha-Santos, T.A.P., Duarte, A.C., Gomes, A.M., Antioxidative peptides: Trends and perspectives for future research. Current Medicinal Chemistry 20 (2013), 4575–4594.
6. Harnedy, P.A., FitzGerald, R.J., Bioactive peptides from marine processing waste and shellfish: A review. Journal of Functional Foods 4:1 (2012), 6–24.
7. Harnedy, P.A., FitzGerald, R.J., Extraction of protein from the macroalga Palmaria palmata. LWT - Food Science and Technology 51:1 (2013), 375–382.
8. Harnedy, P.A., FitzGerald, R.J., In vitro assessment of the cardioprotective, anti-diabetic and antioxidant potential of Palmaria palmata protein hydrolysates. Journal of Applied Phycology 25:6 (2013), 1793–1803.
9. Harnedy, P.A., O'Keeffe, M.B., FitzGerald, R.J., Purification and identification of dipeptidyl peptidase (DPP) IV inhibitory peptides from the macroalga Palmaria palmata. Food Chemistry 172 (2015), 400–406.
10. Harnedy, P.A., Soler-Vila, A., Edwards, M.D., FitzGerald, R.J., The effect of time and origin of harvest on the in vitro biological activity of Palmaria palmata protein hydrolysates. Food Research International 62:0 (2014), 746–752.
11. Hernández-Ledesma, B., Dávalos, A., Bartolomé, B., Amigo, L., Preparation of antioxidant enzymatic hydrolysates from α-lactalbumin and β-lactoglobulin. Identification of active peptides by HPLC-MS/MS. Journal of Agricultural and Food Chemistry 53:3 (2005), 588–593.
12. Li, Y.W., Li, B., Characterization of structure–antioxidant activity relationship of peptides in free radical systems using QSAR models: Key sequence positions and their amino acid properties. Journal of Theoretical Biology 318:0 (2013), 29–43.
13. Lobo, V., Patil, A., Phatak, A., Chandra, N., Free radicals, antioxidants and functional foods: Impact on human health. Pharmacognosy Reviews 4:8 (2010), 118–126.
14. López-Expósito, I., Quirós, A., Amigo, L., Reci, I., Casein hydrolysates as a source of antimicrobial, antioxidant and antihypertensive peptides. Le Lait 87 (2007), 241–249.
15. Nimalaratne, C., Bandara, N., Wu, J., Purification and characterization of antioxidant peptides from enzymatically hydrolyzed chicken egg white. Food Chemistry 188 (2015), 467–472.
16. O'Keeffe, M.B., FitzGerald, R.J., Identification of short peptide sequences in complex milk protein hydrolysates. Food Chemistry 184 (2015), 140–146.
17. O'Keeffe, M.B., Norris, R., Alashi, M.A., Aluko, R.E., FitzGerald, R.J., Peptide identification in a porcine gelatin prolyl endoproteinase hydrolysate with angiotensin converting enzyme (ACE) inhibitory and hypotensive activity. Journal of Functional Foods 34 (2017), 77–88.
18. Power, O., Fernández, A., Norris, R., Riera, F.A., FitzGerald, R.J., Selective enrichment of bioactive properties during ultrafiltration of a tryptic digest of β-lactoglobulin. Journal of Functional Foods 9 (2014), 38–47.
19. Power, O., Jakeman, P., FitzGerald, R.J., Antioxidative peptides: Enzymatic production, in vitro and in vivo antioxidant activity and potential applications of milk-derived antioxidative peptides. Amino Acids 44:3 (2013), 797–820.
20. Sarmadi, B.H., Ismail, A., Antioxidative peptides from food proteins: A review. Peptides 31:10 (2010), 1949–1956.
21. Shahidi, F., Zhong, Y., Antioxidants: regulatory status. Shahidi, F., (eds.) Bailey's industrial oil and fat products, 2005, John Wiley & Sons, Ltd., Hoboken, 491–521.
22. Shen, S., Chahal, B., Majumder, K., You, S.J., Wu, J., Identification of novel antioxidative peptides derived from a thermolytic hydrolysate of ovotransferrin by LC-MS/MS. Journal of Agricultural and Food Chemistry 58:13 (2010), 7664–7672.
23. Udenigwe, C.C., Aluko, R.E., Chemometric analysis of the amino acid requirements of antioxidant food protein hydrolysates. International Journal of Molecular Sciences 12:5 (2011), 3148–3161.
24. Valko, M., Leibfritz, D., Moncol, J., Cronin, M.T.D., Mazur, M., Telser, J., Free radicals and antioxidants in normal physiological functions and human disease. The International Journal of Biochemistry & Cell Biology 39:1 (2007), 44–84.
25. Walsh, D.J., Bernard, H., Murray, B.A., MacDonald, J., Pentzien, A.K., Wright, G.A., FitzGerald, R.J., In vitro generation and stability of the lactokinin beta-lactoglobulin fragment (142–148). Journal of Dairy Science 87:11 (2004), 3845–3857.
26. Wang, T., Jónsdóttir, R., Kristinsson, H.G., Hreggvidsson, G.O., Jónsson, J.O., Thorkelsson, G., Ólafsdóttir, G., Enzyme-enhanced extraction of antioxidant ingredients from red algae Palmaria palmata. LWT - Food Science and Technology 43:9 (2010), 1387–1393.
27. Wang, T., Zhao, Q., Wang, Q., Production and antioxidant properties of marine-derived bioactive peptides. Marine proteins and peptides, 2013, John Wiley & Sons, Ltd., Chichester, 385–406.
28. Yuan, Y.V., Bone, D.E., Carrington, M.F., Antioxidant activity of dulse (Palmaria palmata) extract evaluated in vitro. Food Chemistry 91:3 (2005), 485–494.
29. Yuan, Y.V., Carrington, M.F., Walsh, N.A., Extracts from dulse (Palmaria palmata) are effective antioxidants and inhibitors of cell proliferation in vitro. Food and Chemical Toxicology 43:7 (2005), 1073–1081.
30. Yuan, Y.V., Westcott, N.D., Hu, C., Kitts, D.D., Mycosporine-like amino acid composition of the edible red alga, Palmaria palmata (dulse) harvested from the west and east coasts of Grand Manan Island, New Brunswick. Food Chemistry 112:2 (2009), 321–328.
31. Zheng, L., Su, G., Ren, J., Gu, L., You, L., Zhao, M., Isolation and characterization of an oxygen radical absorbance activity peptide from defatted peanut meal hydrolysate and its antioxidant properties. Journal of Agricultural and Food Chemistry 60:21 (2012), 5431–5437.
32. Zou, T.B., He, T.P., Li, H.B., Tang, H.W., Xia, E.Q., The structure-activity relationship of the antioxidant peptides from natural proteins. Molecules, 21(1), 2016, 72.