Purification and identification of dipeptidyl peptidase (DPP) IV inhibitory peptides from the macroalga Palmaria palmata

Food Chemistry

Volumn 172, Issue , 2015, Pages 400-406

  Harnedy, Pádraigín A ^a   O'Keeffe, Martina B ^a   Fitzgerald, Richard J ^a  

^a UNIVERSITY OF LIMERICK   (Ireland)

Author keywords

Bioactive peptide; Dipeptidyl peptidase IV; Palmaria palmate; Type 2 diabetes

Indexed keywords

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHASE SEPARATION; PURIFICATION;

BIOACTIVE PEPTIDES; DIPEPTIDYL PEPTIDASE; DIPEPTIDYL PEPTIDASE IV; INHIBITORY PEPTIDES; PALMARIA PALMATE; REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID-PHASE EXTRACTION; TYPE-2 DIABETES;

PEPTIDES;

ALANYLISOLEUCYLALANYLVALINE; ALANYLLEUCYLALANYLVALINE; ALGAL EXTRACT; ARGINYLTHREONYLLEUCYLASPARAGINYLLEUCYLPROLYLSERYLALANYLSERINE; DIPEPTIDYL PEPTIDASE IV INHIBITOR; ISOLEUCYLISOLEUCYLALANYLPROLINE; ISOLEUCYLLEUCYLALANYLPROLINE; LEUCYLISOLEUCYLALANYLPROLINE; LEUCYLISOLEUCYLANALYLPROLINE; LEUCYLLEUCYLALANYLPROLINE; METHIONYLALANYLGLYCYLVALYLASPARTYLHISTIDYLISOLEUCINE; METHIONYLALANYLGLYCYLVALYLVALYLASPARTYLHISTIDYLISOLEUCINE; PALMARIA PALMATA EXTRACT; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; VALYLGLYCYLPROLYLASPARTYLALANYLGLYCYLLYSYLGLUTAMYLMETHIONYLGLYCINE; DIPEPTIDYL PEPTIDASE IV; PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; HYDROLYSIS; IC50; MACROALGA; NONHUMAN; PALMARIA PALMATA; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN STABILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID PHASE EXTRACTION; STRUCTURE ACTIVITY RELATION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METABOLISM; RED ALGA; REVERSED PHASE LIQUID CHROMATOGRAPHY;

AMINO ACID SEQUENCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; DIPEPTIDYL PEPTIDASE 4; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; INHIBITORY CONCENTRATION 50; PEPTIDES; RHODOPHYTA; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84907546008     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2014.09.083     Document Type: Article

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