메뉴 건너뛰기




Volumn 32, Issue 4, 2017, Pages 723-733

Human Immunodeficiency Virus Promotes Mitochondrial Toxicity

Author keywords

Ca2+; gp120; HAND; Mitochondria; Neurotoxicity; Tat

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; NEF PROTEIN; TRANSACTIVATOR PROTEIN; VIRAL PROTEIN;

EID: 85022191951     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-017-9776-z     Document Type: Review
Times cited : (44)

References (125)
  • 1
    • 33751183093 scopus 로고    scopus 로고
    • Antioxidant enzyme gene delivery to protect from HIV-1 gp120-induced neuronal apoptosis
    • COI: 1:CAS:528:DC%2BD28Xht1akur3L, PID: 16871233
    • Agrawal L, Louboutin JP, Reyes BA, Van Bockstaele EJ, Strayer DS (2006) Antioxidant enzyme gene delivery to protect from HIV-1 gp120-induced neuronal apoptosis. Gene Ther 13:1645–1656. doi:10.1038/sj.gt.3302821
    • (2006) Gene Ther , vol.13 , pp. 1645-1656
    • Agrawal, L.1    Louboutin, J.P.2    Reyes, B.A.3    Van Bockstaele, E.J.4    Strayer, D.S.5
  • 2
    • 84855760098 scopus 로고    scopus 로고
    • HIV-1 Tat neurotoxicity: a model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes
    • COI: 1:CAS:528:DC%2BC38XovFGqsQ%3D%3D, PID: 22036626
    • Agrawal L, Louboutin JP, Reyes BA, Van Bockstaele EJ, Strayer DS (2012) HIV-1 Tat neurotoxicity: a model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes. Neurobiol Dis 45:657–670. doi:10.1016/j.nbd.2011.10.005
    • (2012) Neurobiol Dis , vol.45 , pp. 657-670
    • Agrawal, L.1    Louboutin, J.P.2    Reyes, B.A.3    Van Bockstaele, E.J.4    Strayer, D.S.5
  • 3
    • 0142011177 scopus 로고    scopus 로고
    • Temporal relationships between HIV-1 Tat-induced neuronal degeneration, OX-42 immunoreactivity, reactive astrocytosis, and protein oxidation in the rat striatum
    • COI: 1:CAS:528:DC%2BD3sXnt1aru7s%3D, PID: 14499939
    • Aksenov MY, Hasselrot U, Wu G, Nath A, Anderson C, Mactutus CF, Booze RM (2003) Temporal relationships between HIV-1 Tat-induced neuronal degeneration, OX-42 immunoreactivity, reactive astrocytosis, and protein oxidation in the rat striatum. Brain Res 987:1–9
    • (2003) Brain Res , vol.987 , pp. 1-9
    • Aksenov, M.Y.1    Hasselrot, U.2    Wu, G.3    Nath, A.4    Anderson, C.5    Mactutus, C.F.6    Booze, R.M.7
  • 4
    • 58149492562 scopus 로고    scopus 로고
    • Neuronal survival and resistance to HIV-1 Tat toxicity in the primary culture of rat fetal neurons
    • COI: 1:CAS:528:DC%2BD1MXmvVentQ%3D%3D, PID: 19013459
    • Aksenova MV, Aksenov MY, Adams SM, Mactutus CF, Booze RM (2009) Neuronal survival and resistance to HIV-1 Tat toxicity in the primary culture of rat fetal neurons. Exp Neurol 215:253–263. doi:10.1016/j.expneurol.2008.10.006
    • (2009) Exp Neurol , vol.215 , pp. 253-263
    • Aksenova, M.V.1    Aksenov, M.Y.2    Adams, S.M.3    Mactutus, C.F.4    Booze, R.M.5
  • 5
    • 4143125610 scopus 로고    scopus 로고
    • Memantine protects hippocampal neuronal function in murine human immunodeficiency virus type 1 encephalitis
    • COI: 1:CAS:528:DC%2BD2cXntFeht7c%3D, PID: 15306653
    • Anderson ER, Gendelman HE, Xiong H (2004) Memantine protects hippocampal neuronal function in murine human immunodeficiency virus type 1 encephalitis. J Neurosci 24:7194–7198. doi:10.1523/JNEUROSCI.1933-04.2004
    • (2004) J Neurosci , vol.24 , pp. 7194-7198
    • Anderson, E.R.1    Gendelman, H.E.2    Xiong, H.3
  • 6
    • 84876733369 scopus 로고    scopus 로고
    • Synaptic dysfunction in human immunodeficiency virus type-1-positive subjects: inflammation or impaired neuronal plasticity?
    • COI: 1:CAS:528:DC%2BC3sXmsFWrtb8%3D, PID: 23600400
    • Avdoshina V, Bachis A, Mocchetti I (2013) Synaptic dysfunction in human immunodeficiency virus type-1-positive subjects: inflammation or impaired neuronal plasticity? J Intern Med 273:454–465. doi:10.1111/joim.12050
    • (2013) J Intern Med , vol.273 , pp. 454-465
    • Avdoshina, V.1    Bachis, A.2    Mocchetti, I.3
  • 8
    • 84961262924 scopus 로고    scopus 로고
    • Identification of a binding site of the human immunodeficiency virus envelope protein gp120 to neuronal-specific tubulin
    • COI: 1:CAS:528:DC%2BC28XktFKmsLs%3D, PID: 26826352
    • Avdoshina V, Taraballi F, Dedoni S, Corbo C, Paige M, Saygideger Kont Y, Uren A, Tasciotti E, Mocchetti I (2016b) Identification of a binding site of the human immunodeficiency virus envelope protein gp120 to neuronal-specific tubulin. J Neurochem 137:287–298. doi:10.1111/jnc.13557
    • (2016) J Neurochem , vol.137 , pp. 287-298
    • Avdoshina, V.1    Taraballi, F.2    Dedoni, S.3    Corbo, C.4    Paige, M.5    Saygideger Kont, Y.6    Uren, A.7    Tasciotti, E.8    Mocchetti, I.9
  • 9
    • 84873621420 scopus 로고    scopus 로고
    • Detection of anti-tat antibodies in CSF of individuals with HIV-associated neurocognitive disorders
    • COI: 1:CAS:528:DC%2BC3sXisVahtb4%3D
    • Bachani M, Sacktor N, McArthur JC, Nath A, Rumbaugh J (2013) Detection of anti-tat antibodies in CSF of individuals with HIV-associated neurocognitive disorders. J Neuro-Oncol 19:82–88. doi:10.1007/s13365-012-0144-8
    • (2013) J Neuro-Oncol , vol.19 , pp. 82-88
    • Bachani, M.1    Sacktor, N.2    McArthur, J.C.3    Nath, A.4    Rumbaugh, J.5
  • 10
    • 0038722025 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor inhibits human immunodeficiency virus-1/gp120-mediated cerebellar granule cell death by preventing gp120 internalization
    • COI: 1:CAS:528:DC%2BD3sXltl2qsbc%3D, PID: 12843275
    • Bachis A, Major EO, Mocchetti I (2003) Brain-derived neurotrophic factor inhibits human immunodeficiency virus-1/gp120-mediated cerebellar granule cell death by preventing gp120 internalization. J Neurosci 23:5715–5722
    • (2003) J Neurosci , vol.23 , pp. 5715-5722
    • Bachis, A.1    Major, E.O.2    Mocchetti, I.3
  • 11
    • 84863691365 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 alters brain-derived neurotrophic factor processing in neurons
    • COI: 1:CAS:528:DC%2BC38XhtVGlsb%2FI, PID: 22787033
    • Bachis A, Avdoshina V, Zecca L, Parsadanian M, Mocchetti I (2012) Human immunodeficiency virus type 1 alters brain-derived neurotrophic factor processing in neurons. J Neurosci 32:9477–9484. doi:10.1523/JNEUROSCI.0865-12.2012
    • (2012) J Neurosci , vol.32 , pp. 9477-9484
    • Bachis, A.1    Avdoshina, V.2    Zecca, L.3    Parsadanian, M.4    Mocchetti, I.5
  • 12
    • 84982719861 scopus 로고    scopus 로고
    • The neurotrophin receptor p75 mediates gp120-induced loss of synaptic spines in aging mice
    • COI: 1:CAS:528:DC%2BC28Xht12jtLzE, PID: 27498053
    • Bachis A, Wenzel E, Boelk A, Becker J, Mocchetti I (2016) The neurotrophin receptor p75 mediates gp120-induced loss of synaptic spines in aging mice. Neurobiol Aging 46:160–168. doi:10.1016/j.neurobiolaging.2016.07.001
    • (2016) Neurobiol Aging , vol.46 , pp. 160-168
    • Bachis, A.1    Wenzel, E.2    Boelk, A.3    Becker, J.4    Mocchetti, I.5
  • 13
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • COI: 1:CAS:528:DC%2BD2MXitVWnurg%3D, PID: 15734681
    • Balaban RS, Nemoto S, Finkel T (2005) Mitochondria, oxidants, and aging. Cell 120:483–495. doi:10.1016/j.cell.2005.02.001
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 14
    • 0029610452 scopus 로고
    • HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures
    • COI: 1:CAS:528:DyaK28XlvVGmsQ%3D%3D, PID: 8821747
    • Bennett BA, Rusyniak DE, Hollingsworth CK (1995) HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures. Brain Res 705:168–176
    • (1995) Brain Res , vol.705 , pp. 168-176
    • Bennett, B.A.1    Rusyniak, D.E.2    Hollingsworth, C.K.3
  • 15
    • 84902276450 scopus 로고    scopus 로고
    • Mitotoxicity in distal symmetrical sensory peripheral neuropathies
    • COI: 1:CAS:528:DC%2BC2cXosVyqtLs%3D, PID: 24840972
    • Bennett GJ, Doyle T, Salvemini D (2014) Mitotoxicity in distal symmetrical sensory peripheral neuropathies. Nat Rev Neurol 10:326–336. doi:10.1038/nrneurol.2014.77
    • (2014) Nat Rev Neurol , vol.10 , pp. 326-336
    • Bennett, G.J.1    Doyle, T.2    Salvemini, D.3
  • 16
    • 84939248947 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore: channel formation by F-ATP synthase, integration in signal transduction, and role in pathophysiology
    • PID: 26269524
    • Bernardi P, Rasola A, Forte M, Lippe G (2015) The mitochondrial permeability transition pore: channel formation by F-ATP synthase, integration in signal transduction, and role in pathophysiology. Physiol Rev 95:1111–1155. doi:10.1152/physrev.00001.2015
    • (2015) Physiol Rev , vol.95 , pp. 1111-1155
    • Bernardi, P.1    Rasola, A.2    Forte, M.3    Lippe, G.4
  • 18
    • 2542427512 scopus 로고    scopus 로고
    • Nitric oxide neurotoxicity in neurodegenerative diseases
    • COI: 1:CAS:528:DC%2BD2cXhtFCrsLc%3D, PID: 14766406
    • Boje KM (2004) Nitric oxide neurotoxicity in neurodegenerative diseases. Front Biosci 9:763–776
    • (2004) Front Biosci , vol.9 , pp. 763-776
    • Boje, K.M.1
  • 19
    • 0030610707 scopus 로고    scopus 로고
    • p75NTR and apoptosis: Trk-dependent and Trk-independent effects
    • COI: 1:CAS:528:DyaK2sXksVequrY%3D, PID: 9223218
    • Bredesen DE, Rabizadeh S (1997) p75NTR and apoptosis: Trk-dependent and Trk-independent effects. Trends Neurosci 20:287–290
    • (1997) Trends Neurosci , vol.20 , pp. 287-290
    • Bredesen, D.E.1    Rabizadeh, S.2
  • 20
    • 0141632883 scopus 로고    scopus 로고
    • Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain
    • COI: 1:CAS:528:DC%2BD3sXnsVGnsro%3D, PID: 12968004
    • Bruce-Keller AJ, Chauhan A, Dimayuga FO, Gee J, Keller JN, Nath A (2003) Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain. J Neurosci 23:8417–8422
    • (2003) J Neurosci , vol.23 , pp. 8417-8422
    • Bruce-Keller, A.J.1    Chauhan, A.2    Dimayuga, F.O.3    Gee, J.4    Keller, J.N.5    Nath, A.6
  • 21
    • 84926258887 scopus 로고    scopus 로고
    • Disturbed mitochondrial dynamics and neurodegenerative disorders
    • COI: 1:CAS:528:DC%2BC2cXitFKntbfM, PID: 25486875
    • Burte F, Carelli V, Chinnery PF, Yu-Wai-Man P (2015) Disturbed mitochondrial dynamics and neurodegenerative disorders. Nat Rev Neurol 11:11–24. doi:10.1038/nrneurol.2014.228
    • (2015) Nat Rev Neurol , vol.11 , pp. 11-24
    • Burte, F.1    Carelli, V.2    Chinnery, P.F.3    Yu-Wai-Man, P.4
  • 22
    • 79954448574 scopus 로고    scopus 로고
    • Neurodegenerative effects of recombinant HIV-1 Tat(1-86) are associated with inhibition of microtubule formation and oxidative stress-related reductions in microtubule-associated protein-2(a,b)
    • COI: 1:CAS:528:DC%2BC3MXovFGktw%3D%3D, PID: 21259049
    • Butler TR, Smith KJ, Self RL, Braden BB, Prendergast MA (2011) Neurodegenerative effects of recombinant HIV-1 Tat(1-86) are associated with inhibition of microtubule formation and oxidative stress-related reductions in microtubule-associated protein-2(a,b). Neurochem Res 36:819–828. doi:10.1007/s11064-011-0409-2
    • (2011) Neurochem Res , vol.36 , pp. 819-828
    • Butler, T.R.1    Smith, K.J.2    Self, R.L.3    Braden, B.B.4    Prendergast, M.A.5
  • 23
    • 0037631328 scopus 로고    scopus 로고
    • Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal transport
    • COI: 1:CAS:528:DC%2BD3sXislGqs7Y%3D, PID: 12551932
    • Chauhan A, Turchan J, Pocernich C, Bruce-Keller A, Roth S, Butterfield DA, Major EO, Nath A (2003) Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal transport. J Biol Chem 278:13512–13519. doi:10.1074/jbc.M209381200
    • (2003) J Biol Chem , vol.278 , pp. 13512-13519
    • Chauhan, A.1    Turchan, J.2    Pocernich, C.3    Bruce-Keller, A.4    Roth, S.5    Butterfield, D.A.6    Major, E.O.7    Nath, A.8
  • 24
    • 12244304872 scopus 로고    scopus 로고
    • HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim
    • COI: 1:CAS:528:DC%2BD38XpslOgs74%3D, PID: 12486001
    • Chen D, Wang M, Zhou S, Zhou Q (2002) HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim. EMBO J 21:6801–6810
    • (2002) EMBO J , vol.21 , pp. 6801-6810
    • Chen, D.1    Wang, M.2    Zhou, S.3    Zhou, Q.4
  • 25
    • 36348934636 scopus 로고    scopus 로고
    • Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members
    • COI: 1:CAS:528:DC%2BD2sXht1OqsrrL, PID: 17893147
    • Chen M, Guerrero AD, Huang L, Shabier Z, Pan M, Tan TH, Wang J (2007) Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members. J Biol Chem 282:33888–33895. doi:10.1074/jbc.M702969200
    • (2007) J Biol Chem , vol.282 , pp. 33888-33895
    • Chen, M.1    Guerrero, A.D.2    Huang, L.3    Shabier, Z.4    Pan, M.5    Tan, T.H.6    Wang, J.7
  • 27
    • 0037183763 scopus 로고    scopus 로고
    • Circulating gp120 alters the blood-brain barrier permeability in HIV-1 gp120 transgenic mice
    • COI: 1:CAS:528:DC%2BD38XntVWrt7g%3D, PID: 12270651
    • Cioni C, Annunziata P (2002) Circulating gp120 alters the blood-brain barrier permeability in HIV-1 gp120 transgenic mice. Neurosci Lett 330:299–301
    • (2002) Neurosci Lett , vol.330 , pp. 299-301
    • Cioni, C.1    Annunziata, P.2
  • 28
    • 84886917428 scopus 로고    scopus 로고
    • HIV-associated neurocognitive disorder
    • PID: 24156898
    • Clifford DB, Ances BM (2013) HIV-associated neurocognitive disorder. Lancet Infect Dis 13:976–986. doi:10.1016/S1473-3099(13)70269-X
    • (2013) Lancet Infect Dis , vol.13 , pp. 976-986
    • Clifford, D.B.1    Ances, B.M.2
  • 30
    • 77953811190 scopus 로고    scopus 로고
    • Mitochondria: the calcium connection
    • COI: 1:CAS:528:DC%2BC3cXnvV2qsrY%3D, PID: 20470749
    • Contreras L, Drago I, Zampese E, Pozzan T (2010) Mitochondria: the calcium connection. Biochim Biophys Acta 1797:607–618. doi:10.1016/j.bbabio.2010.05.005
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 607-618
    • Contreras, L.1    Drago, I.2    Zampese, E.3    Pozzan, T.4
  • 31
    • 0033455558 scopus 로고    scopus 로고
    • Age-related behavioural deficits in transgenic mice expressing the HIV-1 coat protein gp120
    • PID: 10594667
    • D’Hooge R, Franck F, Mucke L, De Deyn PP (1999) Age-related behavioural deficits in transgenic mice expressing the HIV-1 coat protein gp120. Eur J Neurosci 11:4398–4402
    • (1999) Eur J Neurosci , vol.11 , pp. 4398-4402
    • D’Hooge, R.1    Franck, F.2    Mucke, L.3    De Deyn, P.P.4
  • 33
    • 0033934794 scopus 로고    scopus 로고
    • Detection of HIV-1 Tat and JCV capsid protein, VP1, in AIDS brain with progressive multifocal leukoencephalopathy
    • Del Valle L, Croul S, Morgello S, Amini S, Rappaport J, Khalili K (2000) Detection of HIV-1 Tat and JCV capsid protein, VP1, in AIDS brain with progressive multifocal leukoencephalopathy. J Neuro-Oncol 6:221–228
    • (2000) J Neuro-Oncol , vol.6 , pp. 221-228
    • Del Valle, L.1    Croul, S.2    Morgello, S.3    Amini, S.4    Rappaport, J.5    Khalili, K.6
  • 34
    • 34547845247 scopus 로고    scopus 로고
    • An open issue: the inner mitochondrial membrane (IMM) as a free boundary problem
    • COI: 1:CAS:528:DC%2BD2sXpt1Sjs7o%3D, PID: 17560004
    • Demongeot J, Glade N, Hansen O, Moreira A (2007) An open issue: the inner mitochondrial membrane (IMM) as a free boundary problem. Biochimie 89:1049–1057. doi:10.1016/j.biochi.2007.04.009
    • (2007) Biochimie , vol.89 , pp. 1049-1057
    • Demongeot, J.1    Glade, N.2    Hansen, O.3    Moreira, A.4
  • 36
    • 80155137546 scopus 로고    scopus 로고
    • PKA/AKAP1 and PP2A/Bbeta2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics
    • COI: 1:CAS:528:DC%2BC3MXhsVKmsL7E, PID: 22049414
    • Dickey AS, Strack S (2011) PKA/AKAP1 and PP2A/Bbeta2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics. J Neurosci 31:15716–15726. doi:10.1523/JNEUROSCI.3159-11.2011
    • (2011) J Neurosci , vol.31 , pp. 15716-15726
    • Dickey, A.S.1    Strack, S.2
  • 38
    • 33845775666 scopus 로고    scopus 로고
    • HIV and antiretroviral therapy in the brain: neuronal injury and repair
    • COI: 1:CAS:528:DC%2BD28XhtlemtL7O, PID: 17180161
    • Ellis R, Langford D, Masliah E (2007) HIV and antiretroviral therapy in the brain: neuronal injury and repair. Nat Rev Neurosci 8:33–44
    • (2007) Nat Rev Neurosci , vol.8 , pp. 33-44
    • Ellis, R.1    Langford, D.2    Masliah, E.3
  • 39
    • 0027458469 scopus 로고
    • Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation
    • COI: 1:CAS:528:DyaK3sXlsl2qtg%3D%3D, PID: 8416373
    • Ensoli B, Buonaguro L, Barillari G, Fiorelli V, Gendelman R, Morgan RA, Wingfield P, Gallo RC (1993) Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J Virol 67:277–287
    • (1993) J Virol , vol.67 , pp. 277-287
    • Ensoli, B.1    Buonaguro, L.2    Barillari, G.3    Fiorelli, V.4    Gendelman, R.5    Morgan, R.A.6    Wingfield, P.7    Gallo, R.C.8
  • 40
    • 33847649975 scopus 로고    scopus 로고
    • HIV-tat induces formation of an LRP-PSD-95-NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes
    • COI: 1:CAS:528:DC%2BD2sXjtVWltLs%3D
    • Eugenin EA, King JE, Nath A, Calderon TM, Zukin RS, Bennett MVL, Berman JW (2007) HIV-tat induces formation of an LRP-PSD-95-NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes. Proc Nat Acad Sci U S A 104:3438–3443. doi:10.1073/pnas.0611699104
    • (2007) Proc Nat Acad Sci U S A , vol.104 , pp. 3438-3443
    • Eugenin, E.A.1    King, J.E.2    Nath, A.3    Calderon, T.M.4    Zukin, R.S.5    Bennett, M.V.L.6    Berman, J.W.7
  • 41
    • 79960003831 scopus 로고    scopus 로고
    • Human immunodeficiency virus infection of human astrocytes disrupts blood-brain barrier integrity by a gap junction-dependent mechanism
    • COI: 1:CAS:528:DC%2BC3MXoslequ7w%3D, PID: 21715610
    • Eugenin EA, Clements JE, Zink MC, Berman JW (2011) Human immunodeficiency virus infection of human astrocytes disrupts blood-brain barrier integrity by a gap junction-dependent mechanism. J Neurosci 31:9456–9465. doi:10.1523/JNEUROSCI.1460-11.2011
    • (2011) J Neurosci , vol.31 , pp. 9456-9465
    • Eugenin, E.A.1    Clements, J.E.2    Zink, M.C.3    Berman, J.W.4
  • 42
    • 77958561328 scopus 로고    scopus 로고
    • Hyperdopaminergic tone in HIV-1 protein treated rats and cocaine sensitization
    • COI: 1:CAS:528:DC%2BC3cXhsVKktrvI, PID: 20796175
    • Ferris MJ, Frederick-Duus D, Fadel J, Mactutus CF, Booze RM (2010) Hyperdopaminergic tone in HIV-1 protein treated rats and cocaine sensitization. J Neurochem 115:885–896. doi:10.1111/j.1471-4159.2010.06968.x
    • (2010) J Neurochem , vol.115 , pp. 885-896
    • Ferris, M.J.1    Frederick-Duus, D.2    Fadel, J.3    Mactutus, C.F.4    Booze, R.M.5
  • 43
    • 84922390366 scopus 로고    scopus 로고
    • HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders
    • COI: 1:CAS:528:DC%2BC2MXpvFGls7Y%3D, PID: 25653352
    • Fields J, Dumaop W, Eleuteri S, Campos S, Serger E, Trejo M, Kosberg K, Adame A, Spencer B, Rockenstein E, He JJ, Masliah E (2015) HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders. J Neurosci 35:1921–1938. doi:10.1523/JNEUROSCI.3207-14.2015
    • (2015) J Neurosci , vol.35 , pp. 1921-1938
    • Fields, J.1    Dumaop, W.2    Eleuteri, S.3    Campos, S.4    Serger, E.5    Trejo, M.6    Kosberg, K.7    Adame, A.8    Spencer, B.9    Rockenstein, E.10    He, J.J.11    Masliah, E.12
  • 48
    • 33746298246 scopus 로고    scopus 로고
    • Mechanisms of cytochrome c release from mitochondria
    • COI: 1:CAS:528:DC%2BD28XotVylurs%3D, PID: 16676004
    • Garrido C, Galluzzi L, Brunet M, Puig PE, Didelot C, Kroemer G (2006) Mechanisms of cytochrome c release from mitochondria. Cell Death Differ 13:1423–1433. doi:10.1038/sj.cdd.4401950
    • (2006) Cell Death Differ , vol.13 , pp. 1423-1433
    • Garrido, C.1    Galluzzi, L.2    Brunet, M.3    Puig, P.E.4    Didelot, C.5    Kroemer, G.6
  • 50
    • 0036800480 scopus 로고    scopus 로고
    • Calcium dysregulation and neuronal apoptosis by the HIV-1 proteins Tat and gp120
    • COI: 1:CAS:528:DC%2BD38XovFWksLs%3D, PID: 12394783
    • Haughey NJ, Mattson MP (2002) Calcium dysregulation and neuronal apoptosis by the HIV-1 proteins Tat and gp120. J Acquir Immune Defic Syndr 31(Suppl 2):S55–S61
    • (2002) J Acquir Immune Defic Syndr , vol.31 , pp. S55-S61
    • Haughey, N.J.1    Mattson, M.P.2
  • 51
    • 0034909804 scopus 로고    scopus 로고
    • HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity
    • COI: 1:CAS:528:DC%2BD3MXlvFWjur4%3D, PID: 11483648
    • Haughey NJ, Nath A, Mattson MP, Slevin JT, Geiger JD (2001) HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity. J Neurochem 78:457–467
    • (2001) J Neurochem , vol.78 , pp. 457-467
    • Haughey, N.J.1    Nath, A.2    Mattson, M.P.3    Slevin, J.T.4    Geiger, J.D.5
  • 52
    • 62849120358 scopus 로고    scopus 로고
    • GPI-1046 protects dorsal root ganglia from gp120-induced axonal injury by modulating store-operated calcium entry
    • COI: 1:CAS:528:DC%2BD1MXltVOguro%3D, PID: 19335537
    • Hoke A, Morris M, Haughey NJ (2009) GPI-1046 protects dorsal root ganglia from gp120-induced axonal injury by modulating store-operated calcium entry. J Peripher Nerv Syst 14:27–35. doi:10.1111/j.1529-8027.2009.00203.x
    • (2009) J Peripher Nerv Syst , vol.14 , pp. 27-35
    • Hoke, A.1    Morris, M.2    Haughey, N.J.3
  • 53
    • 84951925602 scopus 로고    scopus 로고
    • HIV-1 Tat-mediated calcium Dysregulation and neuronal dysfunction in vulnerable brain regions
    • COI: 1:CAS:528:DC%2BC28XhsVyrtA%3D%3D, PID: 26028040
    • Hu XT (2016) HIV-1 Tat-mediated calcium Dysregulation and neuronal dysfunction in vulnerable brain regions. Curr Drug Targets 17:4–14
    • (2016) Curr Drug Targets , vol.17 , pp. 4-14
    • Hu, X.T.1
  • 54
    • 0034025075 scopus 로고    scopus 로고
    • Detection of the human immunodeficiency virus regulatory protein tat in CNS tissues
    • COI: 1:CAS:528:DC%2BD3cXkt1CrsLw%3D
    • Hudson L, Liu J, Nath A, Jones M, Raghavan R, Narayan O, Male D, Everall I (2000) Detection of the human immunodeficiency virus regulatory protein tat in CNS tissues. J Neuro-Oncol 6:145–155
    • (2000) J Neuro-Oncol , vol.6 , pp. 145-155
    • Hudson, L.1    Liu, J.2    Nath, A.3    Jones, M.4    Raghavan, R.5    Narayan, O.6    Male, D.7    Everall, I.8
  • 55
    • 84867592757 scopus 로고    scopus 로고
    • Role of endolysosomes in HIV-1 Tat-induced neurotoxicity
    • COI: 1:CAS:528:DC%2BC38XpsFyis7Y%3D, PID: 22591512
    • Hui L, Chen X, Haughey NJ, Geiger JD (2012) Role of endolysosomes in HIV-1 Tat-induced neurotoxicity. ASN Neuro 4:243–252. doi:10.1042/AN20120017
    • (2012) ASN Neuro , vol.4 , pp. 243-252
    • Hui, L.1    Chen, X.2    Haughey, N.J.3    Geiger, J.D.4
  • 56
    • 84872833228 scopus 로고    scopus 로고
    • Mitochondrial dynamics in neurodegeneration
    • COI: 1:CAS:528:DC%2BC3sXhs1ektbs%3D, PID: 23159640
    • Itoh K, Nakamura K, Iijima M, Sesaki H (2013) Mitochondrial dynamics in neurodegeneration. Trends Cell Biol 23:64–71. doi:10.1016/j.tcb.2012.10.006
    • (2013) Trends Cell Biol , vol.23 , pp. 64-71
    • Itoh, K.1    Nakamura, K.2    Iijima, M.3    Sesaki, H.4
  • 58
    • 0024535284 scopus 로고
    • Human immunodeficiency virus (HIV) infection and the nervous system: report from the American Academy of Neurology AIDS Task Force
    • COI: 1:STN:280:DyaL1M%2Fot1yhug%3D%3D, PID: 2642609
    • Janssen RS, Cornblath DR, Epstein LG, McArthur J, Price RW (1989) Human immunodeficiency virus (HIV) infection and the nervous system: report from the American Academy of Neurology AIDS Task Force. Neurology 39:119–122
    • (1989) Neurology , vol.39 , pp. 119-122
    • Janssen, R.S.1    Cornblath, D.R.2    Epstein, L.G.3    McArthur, J.4    Price, R.W.5
  • 59
    • 80355129990 scopus 로고    scopus 로고
    • Determination of mitochondrial membrane potential and reactive oxygen species in live rat cortical neurons
    • Joshi DC, Bakowska JC (2011) Determination of mitochondrial membrane potential and reactive oxygen species in live rat cortical neurons. J Vis Exp. doi:10.3791/2704
    • (2011) J Vis Exp
    • Joshi, D.C.1    Bakowska, J.C.2
  • 60
    • 20344384260 scopus 로고    scopus 로고
    • HIV-1 gp120 proteins alter tight junction protein expression and brain endothelial cell permeability: implications for the pathogenesis of HIV-associated dementia
    • COI: 1:CAS:528:DC%2BD2MXlvVSgsbc%3D, PID: 15977641
    • Kanmogne GD, Primeaux C, Grammas P (2005) HIV-1 gp120 proteins alter tight junction protein expression and brain endothelial cell permeability: implications for the pathogenesis of HIV-associated dementia. J Neuropathol Exp Neurol 64:498–505
    • (2005) J Neuropathol Exp Neurol , vol.64 , pp. 498-505
    • Kanmogne, G.D.1    Primeaux, C.2    Grammas, P.3
  • 61
    • 0035912198 scopus 로고    scopus 로고
    • Pathways to neuronal injury and apoptosis in HIV-associated dementia
    • COI: 1:CAS:528:DC%2BD3MXjt1Kqs7g%3D, PID: 11309629
    • Kaul M, Garden GA, Lipton SA (2001) Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 410:988–994
    • (2001) Nature , vol.410 , pp. 988-994
    • Kaul, M.1    Garden, G.A.2    Lipton, S.A.3
  • 62
    • 58149388886 scopus 로고    scopus 로고
    • Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death
    • COI: 1:CAS:528:DC%2BD1cXhsVKgsb3L, PID: 19036954
    • Kim HJ, Martemyanov KA, Thayer SA (2008) Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death. J Neurosci 28:12604–12613. doi:10.1523/JNEUROSCI.2958-08.2008
    • (2008) J Neurosci , vol.28 , pp. 12604-12613
    • Kim, H.J.1    Martemyanov, K.A.2    Thayer, S.A.3
  • 63
    • 84906791789 scopus 로고    scopus 로고
    • HIV-1 protein Tat produces biphasic changes in NMDA-evoked increases in intracellular Ca2+ concentration via activation of Src kinase and nitric oxide signaling pathways
    • COI: 1:CAS:528:DC%2BC2cXhtlOmsL%2FN, PID: 24666322
    • Krogh KA, Wydeven N, Wickman K, Thayer SA (2014) HIV-1 protein Tat produces biphasic changes in NMDA-evoked increases in intracellular Ca2+ concentration via activation of Src kinase and nitric oxide signaling pathways. J Neurochem 130:642–656. doi:10.1111/jnc.12724
    • (2014) J Neurochem , vol.130 , pp. 642-656
    • Krogh, K.A.1    Wydeven, N.2    Wickman, K.3    Thayer, S.A.4
  • 64
    • 0032412520 scopus 로고    scopus 로고
    • HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress
    • COI: 1:CAS:528:DyaK1MXms1Kjsg%3D%3D, PID: 9878167
    • Kruman II, Nath A, Mattson MP (1998) HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress. Exp Neurol 154:276–288. doi:10.1006/exnr.1998.6958
    • (1998) Exp Neurol , vol.154 , pp. 276-288
    • Kruman, I.I.1    Nath, A.2    Mattson, M.P.3
  • 67
    • 79551502732 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in distal axons contributes to human immunodeficiency virus sensory neuropathy
    • COI: 1:CAS:528:DC%2BC3MXisVCis7c%3D, PID: 21280080
    • Lehmann HC, Chen W, Borzan J, Mankowski JL, Hoke A (2011) Mitochondrial dysfunction in distal axons contributes to human immunodeficiency virus sensory neuropathy. Ann Neurol 69:100–110. doi:10.1002/ana.22150
    • (2011) Ann Neurol , vol.69 , pp. 100-110
    • Lehmann, H.C.1    Chen, W.2    Borzan, J.3    Mankowski, J.L.4    Hoke, A.5
  • 68
    • 10944269186 scopus 로고    scopus 로고
    • The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses
    • COI: 1:CAS:528:DC%2BD2MXmsF2n, PID: 15607982
    • Li Z, Okamoto K, Hayashi Y, Sheng M (2004) The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell 119:873–887. doi:10.1016/j.cell.2004.11.003
    • (2004) Cell , vol.119 , pp. 873-887
    • Li, Z.1    Okamoto, K.2    Hayashi, Y.3    Sheng, M.4
  • 70
    • 85013004982 scopus 로고    scopus 로고
    • Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme
    • COI: 1:CAS:528:DC%2BC2sXhvVyqs7k%3D, PID: 28143931
    • Li Y, Zhou M, Hu Q, Bai XC, Huang W, Scheres SH, Shi Y (2017) Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme. Proc Natl Acad Sci U S A 114:1542–1547. doi:10.1073/pnas.1620626114
    • (2017) Proc Natl Acad Sci U S A , vol.114 , pp. 1542-1547
    • Li, Y.1    Zhou, M.2    Hu, Q.3    Bai, X.C.4    Huang, W.5    Scheres, S.H.6    Shi, Y.7
  • 71
    • 0025866327 scopus 로고
    • Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity
    • COI: 1:CAS:528:DyaK3MXlvVWhtrw%3D, PID: 1676893
    • Lipton SA, Sucher NJ, Kaiser PK, Dreyer EB (1991) Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity. Neuron 7:111–118
    • (1991) Neuron , vol.7 , pp. 111-118
    • Lipton, S.A.1    Sucher, N.J.2    Kaiser, P.K.3    Dreyer, E.B.4
  • 72
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
    • COI: 1:CAS:528:DyaK28XktlGnsbY%3D, PID: 8689682
    • Liu X, Kim CN, Yang J, Jemmerson R, Wang X (1996) Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86:147–157
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 73
    • 0034529953 scopus 로고    scopus 로고
    • Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands
    • COI: 1:CAS:528:DC%2BD3cXosl2hs7o%3D, PID: 11100124
    • Liu Y, Jones M, Hingtgen CM, Bu G, Laribee N, Tanzi RE, Moir RD, Nath A, He JJ (2000) Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands. Nat Med 6:1380–1387. doi:10.1038/82199
    • (2000) Nat Med , vol.6 , pp. 1380-1387
    • Liu, Y.1    Jones, M.2    Hingtgen, C.M.3    Bu, G.4    Laribee, N.5    Tanzi, R.E.6    Moir, R.D.7    Nath, A.8    He, J.J.9
  • 74
    • 77955468508 scopus 로고    scopus 로고
    • HIV-1 gp120-induced injury to the blood-brain barrier: role of metalloproteinases 2 and 9 and relationship to oxidative stress
    • COI: 1:CAS:528:DC%2BC3cXpslWgsrc%3D, PID: 20613638
    • Louboutin JP, Agrawal L, Reyes BA, Van Bockstaele EJ, Strayer DS (2010) HIV-1 gp120-induced injury to the blood-brain barrier: role of metalloproteinases 2 and 9 and relationship to oxidative stress. J Neuropathol Exp Neurol 69:801–816. doi:10.1097/NEN.0b013e3181e8c96f
    • (2010) J Neuropathol Exp Neurol , vol.69 , pp. 801-816
    • Louboutin, J.P.1    Agrawal, L.2    Reyes, B.A.3    Van Bockstaele, E.J.4    Strayer, D.S.5
  • 75
    • 84893021363 scopus 로고    scopus 로고
    • BDNF mediates adaptive brain and body responses to energetic challenges
    • COI: 1:CAS:528:DC%2BC3sXhvFOhsLnM, PID: 24361004
    • Marosi K, Mattson MP (2014) BDNF mediates adaptive brain and body responses to energetic challenges. Trends Endocrinol Metab 25:89–98. doi:10.1016/j.tem.2013.10.006
    • (2014) Trends Endocrinol Metab , vol.25 , pp. 89-98
    • Marosi, K.1    Mattson, M.P.2
  • 76
    • 0031470192 scopus 로고    scopus 로고
    • Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders. HNRC Group. The HIV Neurobehavioral Research Center
    • COI: 1:STN:280:DyaK1c%2FmsFOntQ%3D%3D, PID: 9403489
    • Masliah E, Heaton RK, Marcotte TD, Ellis RJ, Wiley CA, Mallory M, Achim CL, McCutchan JA, Nelson JA, Atkinson JH, Grant I (1997) Dendritic injury is a pathological substrate for human immunodeficiency virus-related cognitive disorders. HNRC Group. The HIV Neurobehavioral Research Center. Ann Neurol 42:963–972
    • (1997) Ann Neurol , vol.42 , pp. 963-972
    • Masliah, E.1    Heaton, R.K.2    Marcotte, T.D.3    Ellis, R.J.4    Wiley, C.A.5    Mallory, M.6    Achim, C.L.7    McCutchan, J.A.8    Nelson, J.A.9    Atkinson, J.H.10    Grant, I.11
  • 77
    • 0038751808 scopus 로고    scopus 로고
    • Activation-associated mitochondrial hyperpolarization hijacks T cells toward an apoptosis-sensitized phenotype
    • COI: 1:STN:280:DC%2BD3s3gs1Sksg%3D%3D, PID: 12728259
    • Matarrese P, Cauda R, Malorni W (2003) Activation-associated mitochondrial hyperpolarization hijacks T cells toward an apoptosis-sensitized phenotype. Cell Death Differ 10:609–611. doi:10.1038/sj.cdd.4401212
    • (2003) Cell Death Differ , vol.10 , pp. 609-611
    • Matarrese, P.1    Cauda, R.2    Malorni, W.3
  • 78
    • 22744440922 scopus 로고    scopus 로고
    • Cell death in HIV dementia
    • COI: 1:CAS:528:DC%2BD2MXlsFOmsbc%3D, PID: 15761472
    • Mattson MP, Haughey NJ, Nath A (2005) Cell death in HIV dementia. Cell Death Differ 12(Suppl 1):893–904. doi:10.1038/sj.cdd.4401577
    • (2005) Cell Death Differ , vol.12 , pp. 893-904
    • Mattson, M.P.1    Haughey, N.J.2    Nath, A.3
  • 79
    • 57049143140 scopus 로고    scopus 로고
    • Mitochondria in neuroplasticity and neurological disorders
    • COI: 1:CAS:528:DC%2BD1cXhsFahs7rI, PID: 19081372
    • Mattson MP, Gleichmann M, Cheng A (2008) Mitochondria in neuroplasticity and neurological disorders. Neuron 60:748–766. doi:10.1016/j.neuron.2008.10.010
    • (2008) Neuron , vol.60 , pp. 748-766
    • Mattson, M.P.1    Gleichmann, M.2    Cheng, A.3
  • 80
    • 84903757525 scopus 로고    scopus 로고
    • Sources of DNA double-strand breaks and models of recombinational DNA repair
    • PID: 25104768
    • Mehta A, Haber JE (2014) Sources of DNA double-strand breaks and models of recombinational DNA repair. Cold Spring Harb Perspect Biol 6:a016428. doi:10.1101/cshperspect.a016428
    • (2014) Cold Spring Harb Perspect Biol , vol.6 , pp. a016428
    • Mehta, A.1    Haber, J.E.2
  • 82
    • 0029956028 scopus 로고    scopus 로고
    • gp120-induced neurotoxicity in hippocampal pyramidal neuron cultures: protective action of TGF-beta1
    • COI: 1:CAS:528:DyaK28XjvVGksb0%3D, PID: 8753870
    • Meucci O, Miller RJ (1996) gp120-induced neurotoxicity in hippocampal pyramidal neuron cultures: protective action of TGF-beta1. J Neurosci 16:4080–4088
    • (1996) J Neurosci , vol.16 , pp. 4080-4088
    • Meucci, O.1    Miller, R.J.2
  • 83
    • 84868244723 scopus 로고    scopus 로고
    • Neurobehavioral alterations in HIV-1 transgenic rats: evidence for dopaminergic dysfunction
    • COI: 1:CAS:528:DC%2BC3sXhvVWhtQ%3D%3D, PID: 23063600
    • Moran LM, Booze RM, Webb KM, Mactutus CF (2013) Neurobehavioral alterations in HIV-1 transgenic rats: evidence for dopaminergic dysfunction. Exp Neurol 239:139–147. doi:10.1016/j.expneurol.2012.10.008
    • (2013) Exp Neurol , vol.239 , pp. 139-147
    • Moran, L.M.1    Booze, R.M.2    Webb, K.M.3    Mactutus, C.F.4
  • 84
    • 0033951751 scopus 로고    scopus 로고
    • Synergistic neurotoxicity by human immunodeficiency virus proteins Tat and gp120: protection by memantine
    • COI: 1:CAS:528:DC%2BD3cXhtV2mtrg%3D, PID: 10665489
    • Nath A, Haughey NJ, Jones M, Anderson C, Bell JE, Geiger JD (2000) Synergistic neurotoxicity by human immunodeficiency virus proteins Tat and gp120: protection by memantine. Ann Neurol 47:186–194
    • (2000) Ann Neurol , vol.47 , pp. 186-194
    • Nath, A.1    Haughey, N.J.2    Jones, M.3    Anderson, C.4    Bell, J.E.5    Geiger, J.D.6
  • 85
    • 84875225131 scopus 로고    scopus 로고
    • Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway
    • COI: 1:CAS:528:DC%2BC38XhslKnsbzL
    • Nath S, Bachani M, Harshavardhana D, Steiner JP (2012) Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway. J Neuro-Oncol 18:445–455. doi:10.1007/s13365-012-0122-1
    • (2012) J Neuro-Oncol , vol.18 , pp. 445-455
    • Nath, S.1    Bachani, M.2    Harshavardhana, D.3    Steiner, J.P.4
  • 87
    • 33846230605 scopus 로고    scopus 로고
    • HIV-1 trans activator of transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with dysregulation of complex IV and nicotinamide adenine dinucleotide homeostasis in cortical neurons
    • COI: 1:CAS:528:DC%2BD2sXhvVajuw%3D%3D, PID: 17202348
    • Norman JP, Perry SW, Kasischke KA, Volsky DJ, Gelbard HA (2007) HIV-1 trans activator of transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with dysregulation of complex IV and nicotinamide adenine dinucleotide homeostasis in cortical neurons. J Immunol 178:869–876
    • (2007) J Immunol , vol.178 , pp. 869-876
    • Norman, J.P.1    Perry, S.W.2    Kasischke, K.A.3    Volsky, D.J.4    Gelbard, H.A.5
  • 89
    • 33847325683 scopus 로고    scopus 로고
    • Oxidative stress and toxicity induced by the nucleoside reverse transcriptase inhibitor (NRTI)3′-dideoxycytidine (ddC): relevance to HIV-dementia
    • COI: 1:CAS:528:DC%2BD2sXisVWntrw%3D, PID: 17069802
    • Opii WO, Sultana R, Abdul HM, Ansari MA, Nath A, Butterfield DA (2007) Oxidative stress and toxicity induced by the nucleoside reverse transcriptase inhibitor (NRTI)3′-dideoxycytidine (ddC): relevance to HIV-dementia. Exp Neurol 204:29–38. doi:10.1016/j.expneurol.2006.09.010
    • (2007) Exp Neurol , vol.204 , pp. 29-38
    • Opii, W.O.1    Sultana, R.2    Abdul, H.M.3    Ansari, M.A.4    Nath, A.5    Butterfield, D.A.6
  • 90
    • 0033944598 scopus 로고    scopus 로고
    • Immediate and neurotoxic effects of HIV protein gp120 act through CXCR4 receptor
    • COI: 1:CAS:528:DC%2BD3cXkvFartrk%3D, PID: 10903920
    • Pandey V, Bolsover SR (2000) Immediate and neurotoxic effects of HIV protein gp120 act through CXCR4 receptor. Biochem Biophys Res Commun 274:212–215. doi:10.1006/bbrc.2000.3113
    • (2000) Biochem Biophys Res Commun , vol.274 , pp. 212-215
    • Pandey, V.1    Bolsover, S.R.2
  • 91
    • 33748912842 scopus 로고    scopus 로고
    • Modulation of p75-dependent motor neuron death by a small non-peptidyl mimetic of the neurotrophin loop 1 domain
    • PID: 17004921
    • Pehar M, Cassina P, Vargas MR, Xie Y, Beckman JS, Massa SM, Longo FM, Barbeito L (2006) Modulation of p75-dependent motor neuron death by a small non-peptidyl mimetic of the neurotrophin loop 1 domain. Eur J Neurosci 24:1575–1580. doi:10.1111/j.1460-9568.2006.05040.x
    • (2006) Eur J Neurosci , vol.24 , pp. 1575-1580
    • Pehar, M.1    Cassina, P.2    Vargas, M.R.3    Xie, Y.4    Beckman, J.S.5    Massa, S.M.6    Longo, F.M.7    Barbeito, L.8
  • 92
    • 15444370727 scopus 로고    scopus 로고
    • HIV-1 transactivator of transcription protein induces mitochondrial hyperpolarization and synaptic stress leading to apoptosis
    • COI: 1:CAS:528:DC%2BD2MXisVCht70%3D, PID: 15778398
    • Perry SW, Norman JP, Litzburg A, Zhang D, Dewhurst S, Gelbard HA (2005) HIV-1 transactivator of transcription protein induces mitochondrial hyperpolarization and synaptic stress leading to apoptosis. J Immunol 174:4333–4344
    • (2005) J Immunol , vol.174 , pp. 4333-4344
    • Perry, S.W.1    Norman, J.P.2    Litzburg, A.3    Zhang, D.4    Dewhurst, S.5    Gelbard, H.A.6
  • 93
    • 27744450714 scopus 로고    scopus 로고
    • HIV-dementia, Tat-induced oxidative stress, and antioxidant therapeutic considerations
    • COI: 1:CAS:528:DC%2BD2MXht1SksrnL, PID: 15890409
    • Pocernich CB, Sultana R, Mohmmad-Abdul H, Nath A, Butterfield DA (2005) HIV-dementia, Tat-induced oxidative stress, and antioxidant therapeutic considerations. Brain Res Brain Res Rev 50:14–26. doi:10.1016/j.brainresrev.2005.04.002
    • (2005) Brain Res Brain Res Rev , vol.50 , pp. 14-26
    • Pocernich, C.B.1    Sultana, R.2    Mohmmad-Abdul, H.3    Nath, A.4    Butterfield, D.A.5
  • 94
    • 0032789741 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Tat protein stimulates inducible nitric oxide synthase expression and nitric oxide production in microglial cultures
    • COI: 1:CAS:528:DyaK1MXls1Wgs7w%3D, PID: 10446807
    • Polazzi E, Levi G, Minghetti L (1999) Human immunodeficiency virus type 1 Tat protein stimulates inducible nitric oxide synthase expression and nitric oxide production in microglial cultures. J Neuropathol Exp Neurol 58:825–831
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 825-831
    • Polazzi, E.1    Levi, G.2    Minghetti, L.3
  • 95
    • 19444362384 scopus 로고    scopus 로고
    • HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells
    • COI: 1:CAS:528:DC%2BD2MXks1antr0%3D, PID: 15910762
    • Price TO, Ercal N, Nakaoke R, Banks WA (2005) HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells. Brain Res 1045:57–63. doi:10.1016/j.brainres.2005.03.031
    • (2005) Brain Res , vol.1045 , pp. 57-63
    • Price, T.O.1    Ercal, N.2    Nakaoke, R.3    Banks, W.A.4
  • 96
    • 33747131064 scopus 로고    scopus 로고
    • A novel antioxidant N-acetylcysteine amide prevents gp120- and Tat-induced oxidative stress in brain endothelial cells
    • COI: 1:CAS:528:DC%2BD28XotlKktb8%3D, PID: 16750528
    • Price TO, Uras F, Banks WA, Ercal N (2006) A novel antioxidant N-acetylcysteine amide prevents gp120- and Tat-induced oxidative stress in brain endothelial cells. Exp Neurol 201:193–202. doi:10.1016/j.expneurol.2006.03.030
    • (2006) Exp Neurol , vol.201 , pp. 193-202
    • Price, T.O.1    Uras, F.2    Banks, W.A.3    Ercal, N.4
  • 97
    • 79959344446 scopus 로고    scopus 로고
    • Mitochondria as a therapeutic target for aging and neurodegenerative diseases
    • COI: 1:CAS:528:DC%2BC3MXosFChsbo%3D, PID: 21470101
    • Reddy PH, Reddy TP (2011) Mitochondria as a therapeutic target for aging and neurodegenerative diseases. Curr Alzheimer Res 8:393–409
    • (2011) Curr Alzheimer Res , vol.8 , pp. 393-409
    • Reddy, P.H.1    Reddy, T.P.2
  • 99
    • 84957870064 scopus 로고    scopus 로고
    • Antiretrovirals, methamphetamine, and HIV-1 envelope protein gp120 compromise neuronal energy homeostasis in association with various degrees of synaptic and neuritic damage
    • PID: 26482305
    • Sanchez AB, Varano GP, de Rozieres CM, Maung R, Catalan IC, Dowling CC, Sejbuk NE, Hoefer MM, Kaul M (2015) Antiretrovirals, methamphetamine, and HIV-1 envelope protein gp120 compromise neuronal energy homeostasis in association with various degrees of synaptic and neuritic damage. Antimicrob Agents Chemother 60:168–179. doi:10.1128/AAC.01632-15
    • (2015) Antimicrob Agents Chemother , vol.60 , pp. 168-179
    • Sanchez, A.B.1    Varano, G.P.2    de Rozieres, C.M.3    Maung, R.4    Catalan, I.C.5    Dowling, C.C.6    Sejbuk, N.E.7    Hoefer, M.M.8    Kaul, M.9
  • 102
    • 0041168570 scopus 로고    scopus 로고
    • NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions
    • COI: 1:CAS:528:DyaK1MXhtV2hs7s%3D, PID: 9925788
    • Schuler W, Wecker K, de Rocquigny H, Baudat Y, Sire J, Roques BP (1999) NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions. J Mol Biol 285:2105–2117. doi:10.1006/jmbi.1998.2381
    • (1999) J Mol Biol , vol.285 , pp. 2105-2117
    • Schuler, W.1    Wecker, K.2    de Rocquigny, H.3    Baudat, Y.4    Sire, J.5    Roques, B.P.6
  • 103
    • 0345303772 scopus 로고    scopus 로고
    • The human immunodeficiency virus type-1 transcription factor Tat produces elevations in intracellular Ca2+ that require function of an N-methyl-D-aspartate receptor polyamine-sensitive site
    • COI: 1:CAS:528:DC%2BD3sXptlOrtLg%3D, PID: 14644469
    • Self RL, Mulholland PJ, Nath A, Harris BR, Prendergast MA (2004) The human immunodeficiency virus type-1 transcription factor Tat produces elevations in intracellular Ca2+ that require function of an N-methyl-D-aspartate receptor polyamine-sensitive site. Brain Res 995:39–45
    • (2004) Brain Res , vol.995 , pp. 39-45
    • Self, R.L.1    Mulholland, P.J.2    Nath, A.3    Harris, B.R.4    Prendergast, M.A.5
  • 104
    • 84897567836 scopus 로고    scopus 로고
    • Mitochondrial trafficking and anchoring in neurons: new insight and implications
    • COI: 1:CAS:528:DC%2BC2cXlvFCqtL0%3D, PID: 24687278
    • Sheng ZH (2014) Mitochondrial trafficking and anchoring in neurons: new insight and implications. J Cell Biol 204:1087–1098. doi:10.1083/jcb.201312123
    • (2014) J Cell Biol , vol.204 , pp. 1087-1098
    • Sheng, Z.H.1
  • 105
    • 3042806968 scopus 로고    scopus 로고
    • Apoptotic death of striatal neurons induced by human immunodeficiency virus-1 Tat and gp120: differential involvement of caspase-3 and endonuclease G
    • COI: 1:CAS:528:DC%2BD2cXlsl2nu7c%3D
    • Singh IN, Goody RJ, Dean C, Ahmad NM, Lutz SE, Knapp PE, Nath A, Hauser KF (2004) Apoptotic death of striatal neurons induced by human immunodeficiency virus-1 Tat and gp120: differential involvement of caspase-3 and endonuclease G. J Neuro-Oncol 10:141–151
    • (2004) J Neuro-Oncol , vol.10 , pp. 141-151
    • Singh, I.N.1    Goody, R.J.2    Dean, C.3    Ahmad, N.M.4    Lutz, S.E.5    Knapp, P.E.6    Nath, A.7    Hauser, K.F.8
  • 106
    • 44349087637 scopus 로고    scopus 로고
    • Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration
    • COI: 1:CAS:528:DC%2BD1cXmtlCisLg%3D, PID: 18382462
    • Singh KK, Park KJ, Hong EJ, Kramer BM, Greenberg ME, Kaplan DR, Miller FD (2008) Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration. Nat Neurosci 11:649–658. doi:10.1038/nn.2114
    • (2008) Nat Neurosci , vol.11 , pp. 649-658
    • Singh, K.K.1    Park, K.J.2    Hong, E.J.3    Kramer, B.M.4    Greenberg, M.E.5    Kaplan, D.R.6    Miller, F.D.7
  • 107
    • 0032488243 scopus 로고    scopus 로고
    • Intracellular trafficking and interactions of the HIV-1 Tat protein
    • COI: 1:CAS:528:DyaK1cXotFSitbo%3D, PID: 9875323
    • Stauber RH, Pavlakis GN (1998) Intracellular trafficking and interactions of the HIV-1 Tat protein. Virology 252:126–136
    • (1998) Virology , vol.252 , pp. 126-136
    • Stauber, R.H.1    Pavlakis, G.N.2
  • 108
    • 84931028282 scopus 로고    scopus 로고
    • Creatine protects against mitochondrial dysfunction associated with HIV-1 Tat-induced neuronal injury
    • COI: 1:CAS:528:DC%2BC2MXks1yltr8%3D, PID: 25613139
    • Stevens PR, Gawryluk JW, Hui L, Chen X, Geiger JD (2014) Creatine protects against mitochondrial dysfunction associated with HIV-1 Tat-induced neuronal injury. Curr HIV Res 12:378–387
    • (2014) Curr HIV Res , vol.12 , pp. 378-387
    • Stevens, P.R.1    Gawryluk, J.W.2    Hui, L.3    Chen, X.4    Geiger, J.D.5
  • 109
    • 1842479419 scopus 로고    scopus 로고
    • Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology
    • COI: 1:CAS:528:DC%2BD2cXjsVyqs7g%3D, PID: 14996942
    • Stojanovski D, Koutsopoulos OS, Okamoto K, Ryan MT (2004) Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology. J Cell Sci 117:1201–1210. doi:10.1242/jcs.01058
    • (2004) J Cell Sci , vol.117 , pp. 1201-1210
    • Stojanovski, D.1    Koutsopoulos, O.S.2    Okamoto, K.3    Ryan, M.T.4
  • 110
    • 84892657154 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF)-induced mitochondrial motility arrest and presynaptic docking contribute to BDNF-enhanced synaptic transmission
    • COI: 1:CAS:528:DC%2BC2cXptFyjsg%3D%3D, PID: 24302729
    • Su B, Ji YS, Sun XL, Liu XH, Chen ZY (2014) Brain-derived neurotrophic factor (BDNF)-induced mitochondrial motility arrest and presynaptic docking contribute to BDNF-enhanced synaptic transmission. J Biol Chem 289:1213–1226. doi:10.1074/jbc.M113.526129
    • (2014) J Biol Chem , vol.289 , pp. 1213-1226
    • Su, B.1    Ji, Y.S.2    Sun, X.L.3    Liu, X.H.4    Chen, Z.Y.5
  • 111
    • 0026709499 scopus 로고
    • Human immunodeficiency virus type 1-infected monocytic cells can destroy human neural cells after cell-to-cell adhesion
    • COI: 1:STN:280:DyaK38zlt1aitA%3D%3D, PID: 1303631
    • Tardieu M, Hery C, Peudenier S, Boespflug O, Montagnier L (1992) Human immunodeficiency virus type 1-infected monocytic cells can destroy human neural cells after cell-to-cell adhesion. Ann Neurol 32:11–17. doi:10.1002/ana.410320104
    • (1992) Ann Neurol , vol.32 , pp. 11-17
    • Tardieu, M.1    Hery, C.2    Peudenier, S.3    Boespflug, O.4    Montagnier, L.5
  • 112
    • 84856103312 scopus 로고    scopus 로고
    • Oxygen matters: tissue culture oxygen levels affect mitochondrial function and structure as well as responses to HIV viroproteins
    • COI: 1:STN:280:DC%2BC38%2Fpt1Kmtg%3D%3D, PID: 22190005
    • Tiede LM, Cook EA, Morsey B, Fox HS (2011) Oxygen matters: tissue culture oxygen levels affect mitochondrial function and structure as well as responses to HIV viroproteins. Cell Death Dis 2:e246. doi:10.1038/cddis.2011.128
    • (2011) Cell Death Dis , vol.2
    • Tiede, L.M.1    Cook, E.A.2    Morsey, B.3    Fox, H.S.4
  • 113
    • 85011769647 scopus 로고    scopus 로고
    • Mitochondria and synaptic plasticity in the mature and aging nervous system
    • COI: 1:CAS:528:DC%2BC2sXjs1WrtQ%3D%3D, PID: 27075203
    • Todorova V, Blokland A (2017) Mitochondria and synaptic plasticity in the mature and aging nervous system. Curr Neuropharmacol 15:166–173
    • (2017) Curr Neuropharmacol , vol.15 , pp. 166-173
    • Todorova, V.1    Blokland, A.2
  • 114
    • 0028009187 scopus 로고
    • Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice
    • COI: 1:CAS:528:DyaK2cXhs1Sgtbc%3D, PID: 8114918
    • Toggas SM, Masliah E, Rockenstein EM, Rall GF, Abraham CR, Mucke L (1994) Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice. Nature 367:188–193
    • (1994) Nature , vol.367 , pp. 188-193
    • Toggas, S.M.1    Masliah, E.2    Rockenstein, E.M.3    Rall, G.F.4    Abraham, C.R.5    Mucke, L.6
  • 117
    • 84957542019 scopus 로고    scopus 로고
    • HIV-1 transgenic rats display mitochondrial abnormalities consistent with abnormal energy generation and distribution
    • COI: 1:CAS:528:DC%2BC28XitV2ltrk%3D
    • Villeneuve LM, Purnell PR, Stauch KL, Callen SE, Buch SJ, Fox HS (2016) HIV-1 transgenic rats display mitochondrial abnormalities consistent with abnormal energy generation and distribution. J Neuro-Oncol 22:564–574. doi:10.1007/s13365-016-0424-9
    • (2016) J Neuro-Oncol , vol.22 , pp. 564-574
    • Villeneuve, L.M.1    Purnell, P.R.2    Stauch, K.L.3    Callen, S.E.4    Buch, S.J.5    Fox, H.S.6
  • 119
    • 78649413837 scopus 로고    scopus 로고
    • Mitochondrial fusion and fission in cell life and death
    • COI: 1:CAS:528:DC%2BC3cXhsVGrurnN, PID: 21102612
    • Westermann B (2010) Mitochondrial fusion and fission in cell life and death. Nat Rev Mol Cell Biol 11:872–884. doi:10.1038/nrm3013
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 872-884
    • Westermann, B.1
  • 120
    • 84957430700 scopus 로고    scopus 로고
    • Opposing effects of NGF and proNGF on HIV induced macrophage activation
    • PID: 26420421
    • Williams KS, Killebrew DA, Clary GP, Meeker RB (2016) Opposing effects of NGF and proNGF on HIV induced macrophage activation. J NeuroImmune Pharmacol 11:98–120. doi:10.1007/s11481-015-9631-z
    • (2016) J NeuroImmune Pharmacol , vol.11 , pp. 98-120
    • Williams, K.S.1    Killebrew, D.A.2    Clary, G.P.3    Meeker, R.B.4
  • 121
  • 122
    • 81855224923 scopus 로고    scopus 로고
    • The human immunodeficiency virus coat protein gp120 promotes forward trafficking and surface clustering of NMDA receptors in membrane microdomains
    • COI: 1:CAS:528:DC%2BC3MXhsFOhs7rL, PID: 22114277
    • Xu H, Bae M, Tovar-y-Romo LB, Patel N, Bandaru VV, Pomerantz D, Steiner JP, Haughey NJ (2011) The human immunodeficiency virus coat protein gp120 promotes forward trafficking and surface clustering of NMDA receptors in membrane microdomains. J Neurosci 31:17074–17090. doi:10.1523/JNEUROSCI.4072-11.2011
    • (2011) J Neurosci , vol.31 , pp. 17074-17090
    • Xu, H.1    Bae, M.2    Tovar-y-Romo, L.B.3    Patel, N.4    Bandaru, V.V.5    Pomerantz, D.6    Steiner, J.P.7    Haughey, N.J.8
  • 124
    • 33749265862 scopus 로고    scopus 로고
    • Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1
    • COI: 1:CAS:528:DC%2BD28XhtVClu7fI, PID: 16883569
    • Yoon YS, Yoon DS, Lim IK, Yoon SH, Chung HY, Rojo M, Malka F, Jou MJ, Martinou JC, Yoon G (2006) Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1. J Cell Physiol 209:468–480. doi:10.1002/jcp.20753
    • (2006) J Cell Physiol , vol.209 , pp. 468-480
    • Yoon, Y.S.1    Yoon, D.S.2    Lim, I.K.3    Yoon, S.H.4    Chung, H.Y.5    Rojo, M.6    Malka, F.7    Jou, M.J.8    Martinou, J.C.9    Yoon, G.10
  • 125
    • 84861199913 scopus 로고    scopus 로고
    • Accumulation of nuclear and mitochondrial DNA damage in the frontal cortex cells of patients with HIV-associated neurocognitive disorders
    • COI: 1:CAS:528:DC%2BC38Xntlaisr0%3D, PID: 22554480
    • Zhang Y, Wang M, Li H, Zhang H, Shi Y, Wei F, Liu D, Liu K, Chen D (2012) Accumulation of nuclear and mitochondrial DNA damage in the frontal cortex cells of patients with HIV-associated neurocognitive disorders. Brain Res 1458:1–11. doi:10.1016/j.brainres.2012.04.001
    • (2012) Brain Res , vol.1458 , pp. 1-11
    • Zhang, Y.1    Wang, M.2    Li, H.3    Zhang, H.4    Shi, Y.5    Wei, F.6    Liu, D.7    Liu, K.8    Chen, D.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.