메뉴 건너뛰기




Volumn 54, Issue 3, 2014, Pages 485-493

PACAP27 is Protective Against Tat-Induced Neurotoxicity

Author keywords

CCL5; DNA damage; gp120; HIV; Mitochondria; Oxidative stress

Indexed keywords

HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; NEUROPROTECTIVE AGENT; RANTES; REACTIVE OXYGEN METABOLITE; TRANSACTIVATOR PROTEIN;

EID: 84897329568     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0273-z     Document Type: Article
Times cited : (27)

References (52)
  • 1
    • 33846923131 scopus 로고    scopus 로고
    • Dementia and neurocognitive disorders due to HIV-1 infection
    • PID: 17226745
    • Ances BM, Ellis RJ (2007) Dementia and neurocognitive disorders due to HIV-1 infection. Semin Neurol 27:86–92
    • (2007) Semin Neurol , vol.27 , pp. 86-92
    • Ances, B.M.1    Ellis, R.J.2
  • 2
    • 77957367692 scopus 로고    scopus 로고
    • Morphine induces the release of CCL5 from astrocytes: potential neuroprotective mechanism against the HIV protein gp120
    • PID: 20578038
    • Avdoshina V, Biggio F, Palchik G, Campbell LA, Mocchetti I (2010) Morphine induces the release of CCL5 from astrocytes: potential neuroprotective mechanism against the HIV protein gp120. Glia 58:1630–1639
    • (2010) Glia , vol.58 , pp. 1630-1639
    • Avdoshina, V.1    Biggio, F.2    Palchik, G.3    Campbell, L.A.4    Mocchetti, I.5
  • 3
    • 0038722025 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor inhibits human immunodeficiency virus-1/gp120-mediated cerebellar granule cell death by preventing gp120 internalization
    • COI: 1:CAS:528:DC%2BD3sXltl2qsbc%3D, PID: 12843275
    • Bachis A, Major EO, Mocchetti I (2003) Brain-derived neurotrophic factor inhibits human immunodeficiency virus-1/gp120-mediated cerebellar granule cell death by preventing gp120 internalization. J Neurosci 23:5715–5722
    • (2003) J Neurosci , vol.23 , pp. 5715-5722
    • Bachis, A.1    Major, E.O.2    Mocchetti, I.3
  • 4
    • 79960313884 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating peptide induces long-lasting neuroprotection through the induction of activity-dependent signaling via the cyclic AMP response element-binding protein-regulated transcription co-activator 1
    • COI: 1:CAS:528:DC%2BC3MXhtVSit7vP, PID: 21623792
    • Baxter PS, Martel M-A, McMahon A, Kind PC, Hardingham GE (2011) Pituitary adenylate cyclase-activating peptide induces long-lasting neuroprotection through the induction of activity-dependent signaling via the cyclic AMP response element-binding protein-regulated transcription co-activator 1. J Neurochem 118:365–378
    • (2011) J Neurochem , vol.118 , pp. 365-378
    • Baxter, P.S.1    Martel, M.-A.2    McMahon, A.3    Kind, P.C.4    Hardingham, G.E.5
  • 5
    • 33747476112 scopus 로고    scopus 로고
    • Protecting the synapse: evidence for a rational strategy to treat HIV-1 associated neurologic disease
    • Bellizzi MJ, Lu SM, Gelbard HA (2006) Protecting the synapse: evidence for a rational strategy to treat HIV-1 associated neurologic disease. J Neuroimmune Pharm 1:20–31
    • (2006) J Neuroimmune Pharm , vol.1 , pp. 20-31
    • Bellizzi, M.J.1    Lu, S.M.2    Gelbard, H.A.3
  • 6
    • 44949091276 scopus 로고    scopus 로고
    • Accumulation of nuclear DNA damage or neuron loss: molecular basis for a new approach to understanding selective neuronal vulnerability in neurodegenerative diseases
    • COI: 1:CAS:528:DC%2BD1cXnt1aktrw%3D
    • Brasnjevic I, Hof PR, Steinbusch HW, Schmitz C (2008) Accumulation of nuclear DNA damage or neuron loss: molecular basis for a new approach to understanding selective neuronal vulnerability in neurodegenerative diseases. DNA Repair (Amst) 7:1087–1097
    • (2008) DNA Repair (Amst) , vol.7 , pp. 1087-1097
    • Brasnjevic, I.1    Hof, P.R.2    Steinbusch, H.W.3    Schmitz, C.4
  • 7
    • 0023786731 scopus 로고
    • Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide
    • COI: 1:CAS:528:DyaL1cXmt1ygurk%3D, PID: 2845276
    • Brenneman DE, Westbrook GL, Fitzgerald SP et al (1988) Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide. Nature 335:639–642
    • (1988) Nature , vol.335 , pp. 639-642
    • Brenneman, D.E.1    Westbrook, G.L.2    Fitzgerald, S.P.3
  • 8
    • 0036700820 scopus 로고    scopus 로고
    • Chemokine release is associated with the protective action of PACAP-38 against HIV envelope protein neurotoxicity
    • COI: 1:CAS:528:DC%2BD38Xos1yiu74%3D, PID: 12372701
    • Brenneman DE, Hauser JM, Spong C, Phillips TM (2002) Chemokine release is associated with the protective action of PACAP-38 against HIV envelope protein neurotoxicity. Neuropeptides 36:271–280
    • (2002) Neuropeptides , vol.36 , pp. 271-280
    • Brenneman, D.E.1    Hauser, J.M.2    Spong, C.3    Phillips, T.M.4
  • 9
    • 0141632883 scopus 로고    scopus 로고
    • Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain
    • COI: 1:CAS:528:DC%2BD3sXnsVGnsro%3D, PID: 12968004
    • Bruce-Keller AJ, Chauhan A, Dimayuga FO, Gee J, Keller JN, Nath A (2003) Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain. J Neurosci 23:8417–8422
    • (2003) J Neurosci , vol.23 , pp. 8417-8422
    • Bruce-Keller, A.J.1    Chauhan, A.2    Dimayuga, F.O.3    Gee, J.4    Keller, J.N.5    Nath, A.6
  • 10
    • 0030884230 scopus 로고    scopus 로고
    • The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases
    • COI: 1:CAS:528:DyaK2sXlvFGisb4%3D, PID: 9278385
    • Chen P, Mayne M, Power C, Nath A (1997) The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases. J Biol Chem 272:22385–22388
    • (1997) J Biol Chem , vol.272 , pp. 22385-22388
    • Chen, P.1    Mayne, M.2    Power, C.3    Nath, A.4
  • 11
    • 12244304872 scopus 로고    scopus 로고
    • HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim
    • COI: 1:CAS:528:DC%2BD38XpslOgs74%3D, PID: 12486001
    • Chen D, Wang M, Zhou S, Zhou Q (2002) HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim. EMBO J 21:6801–6810
    • (2002) EMBO J , vol.21 , pp. 6801-6810
    • Chen, D.1    Wang, M.2    Zhou, S.3    Zhou, Q.4
  • 12
    • 63449133676 scopus 로고    scopus 로고
    • Molecular pathology of neuro-AIDS (CNS-HIV)
    • COI: 1:CAS:528:DC%2BD1MXjsVOru7g%3D, PID: 19399237
    • Crews L, Patrick C, Achim CL, Everall IP, Masliah E (2009) Molecular pathology of neuro-AIDS (CNS-HIV). Int J Mol Sci 10:1045–1063
    • (2009) Int J Mol Sci , vol.10 , pp. 1045-1063
    • Crews, L.1    Patrick, C.2    Achim, C.L.3    Everall, I.P.4    Masliah, E.5
  • 13
    • 84857665309 scopus 로고    scopus 로고
    • Receptor-independent cellular uptake of pituitary adenylate cyclase-activating polypeptide
    • COI: 1:CAS:528:DC%2BC38Xkslejs70%3D, PID: 22343001
    • Doan ND, Chatenet D, Letourneau M, Vaudry H, Vaudry D, Fournier A (2012) Receptor-independent cellular uptake of pituitary adenylate cyclase-activating polypeptide. Biochim Biophys Acta 1823:940–949
    • (2012) Biochim Biophys Acta , vol.1823 , pp. 940-949
    • Doan, N.D.1    Chatenet, D.2    Letourneau, M.3    Vaudry, H.4    Vaudry, D.5    Fournier, A.6
  • 14
    • 84870670254 scopus 로고    scopus 로고
    • Mitochondria: mitochondrial membranes in brain ageing and neurodegeneration
    • COI: 1:CAS:528:DC%2BC38XhtVOlsbvP, PID: 22743330
    • Eckmann J, Eckert SH, Leuner K, Muller WE, Eckert GP (2013) Mitochondria: mitochondrial membranes in brain ageing and neurodegeneration. Int J Biochem Cell Biol 45:76–80
    • (2013) Int J Biochem Cell Biol , vol.45 , pp. 76-80
    • Eckmann, J.1    Eckert, S.H.2    Leuner, K.3    Muller, W.E.4    Eckert, G.P.5
  • 15
    • 33847649975 scopus 로고    scopus 로고
    • HIV-tat induces formation of an LRP-PSD-95-NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes
    • COI: 1:CAS:528:DC%2BD2sXjtVWltLs%3D, PID: 17360663
    • Eugenin EA, King JE, Nath A et al (2007) HIV-tat induces formation of an LRP-PSD-95-NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes. Proc Natl Acad Sci U S A 104:3438–3443
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3438-3443
    • Eugenin, E.A.1    King, J.E.2    Nath, A.3
  • 16
    • 84868204348 scopus 로고    scopus 로고
    • Effects of PACAP on intracellular signaling pathways in human retinal pigment epithelial cells exposed to oxidative stress
    • COI: 1:CAS:528:DC%2BC38XhtlKkurnJ, PID: 22644900
    • Fabian E, Reglodi D, Mester L et al (2012) Effects of PACAP on intracellular signaling pathways in human retinal pigment epithelial cells exposed to oxidative stress. J Mol Neurosci 48:493–500
    • (2012) J Mol Neurosci , vol.48 , pp. 493-500
    • Fabian, E.1    Reglodi, D.2    Mester, L.3
  • 17
    • 33845518305 scopus 로고    scopus 로고
    • DNA repair in neurons: so if they don’t divide what’s to repair?
    • COI: 1:CAS:528:DC%2BD28Xhtlaqs7nK, PID: 16879837
    • Fishel ML, Vasko MR, Kelley MR (2007) DNA repair in neurons: so if they don’t divide what’s to repair? Mutat Res 614:24–36
    • (2007) Mutat Res , vol.614 , pp. 24-36
    • Fishel, M.L.1    Vasko, M.R.2    Kelley, M.R.3
  • 18
    • 0037095687 scopus 로고    scopus 로고
    • Caspase cascades in human immunodeficiency virus-associated neurodegeneration
    • COI: 1:CAS:528:DC%2BD38XjvVagtL0%3D, PID: 12019321
    • Garden GA, Budd SL, Tsai E et al (2002) Caspase cascades in human immunodeficiency virus-associated neurodegeneration. J Neurosci 22:4015–4024
    • (2002) J Neurosci , vol.22 , pp. 4015-4024
    • Garden, G.A.1    Budd, S.L.2    Tsai, E.3
  • 19
    • 0034909804 scopus 로고    scopus 로고
    • HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity
    • COI: 1:CAS:528:DC%2BD3MXlvFWjur4%3D, PID: 11483648
    • Haughey NJ, Nath A, Mattson MP, Slevin JT, Geiger JD (2001) HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity. J Neurochem 78:457–467
    • (2001) J Neurochem , vol.78 , pp. 457-467
    • Haughey, N.J.1    Nath, A.2    Mattson, M.P.3    Slevin, J.T.4    Geiger, J.D.5
  • 20
    • 79952921819 scopus 로고    scopus 로고
    • HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors
    • COI: 1:CAS:528:DC%2BC3MXisVyrtb8%3D, PID: 21174240
    • Heaton RK, Franklin DR, Ellis RJ et al (2011) HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors. J Neurovirol 17:3–16
    • (2011) J Neurovirol , vol.17 , pp. 3-16
    • Heaton, R.K.1    Franklin, D.R.2    Ellis, R.J.3
  • 22
    • 84872833228 scopus 로고    scopus 로고
    • Mitochondrial dynamics in neurodegeneration
    • COI: 1:CAS:528:DC%2BC3sXhs1ektbs%3D, PID: 23159640
    • Itoh K, Nakamura K, Iijima M, Sesaki H (2013) Mitochondrial dynamics in neurodegeneration. Trends Cell Biol 23:64–71
    • (2013) Trends Cell Biol , vol.23 , pp. 64-71
    • Itoh, K.1    Nakamura, K.2    Iijima, M.3    Sesaki, H.4
  • 23
    • 0032726178 scopus 로고    scopus 로고
    • Expression of caspase-3 in brains from paediatric patients with HIV-1 encephalitis
    • COI: 1:STN:280:DC%2BD3c%2Fjt1Slsw%3D%3D, PID: 10564527
    • James HJ, Sharer LR, Zhang Q et al (1999) Expression of caspase-3 in brains from paediatric patients with HIV-1 encephalitis. Neuropathol Appl Neurobiol 25:380–386
    • (1999) Neuropathol Appl Neurobiol , vol.25 , pp. 380-386
    • James, H.J.1    Sharer, L.R.2    Zhang, Q.3
  • 24
    • 79956205888 scopus 로고    scopus 로고
    • DNA repair deficiency in neurodegeneration
    • COI: 1:CAS:528:DC%2BC3MXntlGrsLs%3D, PID: 21550379
    • Jeppesen DK, Bohr VA, Stevnsner T (2011) DNA repair deficiency in neurodegeneration. Prog Neurobiol 94:166–200
    • (2011) Prog Neurobiol , vol.94 , pp. 166-200
    • Jeppesen, D.K.1    Bohr, V.A.2    Stevnsner, T.3
  • 25
    • 27744507622 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase activating polypeptide plays a role in olfactory memory formation in chicken
    • COI: 1:CAS:528:DC%2BD2MXhtFylurvK, PID: 15927304
    • Jozsa R, Hollosy T, Tamas A, Toth G, Lengvari I, Reglodi D (2005) Pituitary adenylate cyclase activating polypeptide plays a role in olfactory memory formation in chicken. Peptides 26:2344–2350
    • (2005) Peptides , vol.26 , pp. 2344-2350
    • Jozsa, R.1    Hollosy, T.2    Tamas, A.3    Toth, G.4    Lengvari, I.5    Reglodi, D.6
  • 26
    • 0343826872 scopus 로고    scopus 로고
    • PACAP38 and PACAP27 administered intracerebroventricularly have an opposite effect on LH secretion
    • COI: 1:CAS:528:DC%2BD3cXlvFWhs78%3D, PID: 10959003
    • Kantora O, Molnar J, Arimura A, Koves K (2000) PACAP38 and PACAP27 administered intracerebroventricularly have an opposite effect on LH secretion. Peptides 21:817–820
    • (2000) Peptides , vol.21 , pp. 817-820
    • Kantora, O.1    Molnar, J.2    Arimura, A.3    Koves, K.4
  • 27
    • 0035912198 scopus 로고    scopus 로고
    • Pathways to neuronal injury and apoptosis in HIV-associated dementia
    • COI: 1:CAS:528:DC%2BD3MXjt1Kqs7g%3D, PID: 11309629
    • Kaul M, Garden GA, Lipton SA (2001) Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 410:988–994
    • (2001) Nature , vol.410 , pp. 988-994
    • Kaul, M.1    Garden, G.A.2    Lipton, S.A.3
  • 28
    • 33846217344 scopus 로고    scopus 로고
    • HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection
    • COI: 1:CAS:528:DC%2BD2sXkslChtg%3D%3D, PID: 16841089
    • Kaul M, Ma Q, Medders KE, Desai MK, Lipton SA (2007) HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection. Cell Death Differ 14:296–305
    • (2007) Cell Death Differ , vol.14 , pp. 296-305
    • Kaul, M.1    Ma, Q.2    Medders, K.E.3    Desai, M.K.4    Lipton, S.A.5
  • 29
    • 58149388886 scopus 로고    scopus 로고
    • Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death
    • COI: 1:CAS:528:DC%2BD1cXhsVKgsb3L, PID: 19036954
    • Kim HJ, Martemyanov KA, Thayer SA (2008) Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death. J Neurosci 28:12604–12613
    • (2008) J Neurosci , vol.28 , pp. 12604-12613
    • Kim, H.J.1    Martemyanov, K.A.2    Thayer, S.A.3
  • 30
    • 0032412520 scopus 로고    scopus 로고
    • HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress
    • COI: 1:CAS:528:DyaK1MXms1Kjsg%3D%3D, PID: 9878167
    • Kruman II, Nath A, Mattson MP (1998) HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress. Exp Neurol 154:276–288
    • (1998) Exp Neurol , vol.154 , pp. 276-288
    • Kruman, I.I.1    Nath, A.2    Mattson, M.P.3
  • 31
    • 0037088607 scopus 로고    scopus 로고
    • Activation of Trk neurotrophin receptor signaling by pituitary adenylate cyclase-activating polypeptides
    • COI: 1:CAS:528:DC%2BD38Xitl2ksrs%3D, PID: 11784714
    • Lee FS, Rajagopal R, Kim AH, Chang PC, Chao MV (2002) Activation of Trk neurotrophin receptor signaling by pituitary adenylate cyclase-activating polypeptides. J Biol Chem 277:9096–9102
    • (2002) J Biol Chem , vol.277 , pp. 9096-9102
    • Lee, F.S.1    Rajagopal, R.2    Kim, A.H.3    Chang, P.C.4    Chao, M.V.5
  • 32
    • 58149393846 scopus 로고    scopus 로고
    • NMDA receptor activation by HIV-Tat protein is clade dependent
    • COI: 1:CAS:528:DC%2BD1cXhsVGmtLvP, PID: 19020013
    • Li W, Huang Y, Reid R et al (2008) NMDA receptor activation by HIV-Tat protein is clade dependent. J Neurosci 28:12190–12198
    • (2008) J Neurosci , vol.28 , pp. 12190-12198
    • Li, W.1    Huang, Y.2    Reid, R.3
  • 33
    • 70349900678 scopus 로고    scopus 로고
    • Role of Tat protein in HIV neuropathogenesis
    • COI: 1:CAS:528:DC%2BD1MXhtFOkt7nL, PID: 19526283
    • Li W, Li G, Steiner J, Nath A (2009) Role of Tat protein in HIV neuropathogenesis. Neurotox Res 16:205–220
    • (2009) Neurotox Res , vol.16 , pp. 205-220
    • Li, W.1    Li, G.2    Steiner, J.3    Nath, A.4
  • 34
    • 2642640418 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP) protects dorsal root ganglion neurons from death and induces calcitonin gene-related peptide (CGRP) immunoreactivity in vitro
    • COI: 1:CAS:528:DyaK1cXnt1SntQ%3D%3D, PID: 9469578
    • Lioudyno M, Skoglösa Y, Takei N, Lindholm D (1998) Pituitary adenylate cyclase-activating polypeptide (PACAP) protects dorsal root ganglion neurons from death and induces calcitonin gene-related peptide (CGRP) immunoreactivity in vitro. J Neurosci Res 51:243–256
    • (1998) J Neurosci Res , vol.51 , pp. 243-256
    • Lioudyno, M.1    Skoglösa, Y.2    Takei, N.3    Lindholm, D.4
  • 35
    • 0034529953 scopus 로고    scopus 로고
    • Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands
    • COI: 1:CAS:528:DC%2BD3cXosl2hs7o%3D, PID: 11100124
    • Liu Y, Jones M, Hingtgen CM et al (2000) Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands. Nat Med 6:1380–1387
    • (2000) Nat Med , vol.6 , pp. 1380-1387
    • Liu, Y.1    Jones, M.2    Hingtgen, C.M.3
  • 36
    • 0031052029 scopus 로고    scopus 로고
    • Molecular determinants for cellular uptake of Tat protein of human immunodeficiency virus type 1 in brain cells
    • COI: 1:CAS:528:DyaK2sXht1ajsbY%3D, PID: 9032389
    • Ma M, Nath A (1997) Molecular determinants for cellular uptake of Tat protein of human immunodeficiency virus type 1 in brain cells. J Virol 71:2495–2499
    • (1997) J Virol , vol.71 , pp. 2495-2499
    • Ma, M.1    Nath, A.2
  • 37
    • 22744440922 scopus 로고    scopus 로고
    • Cell death in HIV dementia
    • COI: 1:CAS:528:DC%2BD2MXlsFOmsbc%3D, PID: 15761472
    • Mattson MP, Haughey NJ, Nath A (2005) Cell death in HIV dementia. Cell Death Differ 12(Suppl 1):893–904
    • (2005) Cell Death Differ , vol.12 , pp. 893-904
    • Mattson, M.P.1    Haughey, N.J.2    Nath, A.3
  • 38
    • 77951223899 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival
    • COI: 1:CAS:528:DC%2BC3cXjsFehtL0%3D, PID: 20093365
    • May V, Lutz E, MacKenzie C, Schutz KC, Dozark K, Braas KM (2010) Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival. J Biol Chem 285:9749–9761
    • (2010) J Biol Chem , vol.285 , pp. 9749-9761
    • May, V.1    Lutz, E.2    MacKenzie, C.3    Schutz, K.C.4    Dozark, K.5    Braas, K.M.6
  • 39
    • 84875225131 scopus 로고    scopus 로고
    • Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway
    • COI: 1:CAS:528:DC%2BC38XhslKnsbzL, PID: 22886603
    • Nath S, Bachani M, Harshavardhana D, Steiner JP (2012) Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway. J Neurovirol 18:445–455
    • (2012) J Neurovirol , vol.18 , pp. 445-455
    • Nath, S.1    Bachani, M.2    Harshavardhana, D.3    Steiner, J.P.4
  • 40
    • 33846230605 scopus 로고    scopus 로고
    • HIV-1 trans activator of transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with dysregulation of complex IV and nicotinamide adenine dinucleotide homeostasis in cortical neurons
    • COI: 1:CAS:528:DC%2BD2sXhvVajuw%3D%3D, PID: 17202348
    • Norman JP, Perry SW, Kasischke KA, Volsky DJ, Gelbard HA (2007) HIV-1 trans activator of transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with dysregulation of complex IV and nicotinamide adenine dinucleotide homeostasis in cortical neurons. J Immunol 178:869–876
    • (2007) J Immunol , vol.178 , pp. 869-876
    • Norman, J.P.1    Perry, S.W.2    Kasischke, K.A.3    Volsky, D.J.4    Gelbard, H.A.5
  • 41
    • 56649102055 scopus 로고    scopus 로고
    • HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization
    • PID: 19009018
    • Norman JP, Perry SW, Reynolds HM et al (2008) HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization. PLoS One 3:e3731
    • (2008) PLoS One , vol.3 , pp. e3731
    • Norman, J.P.1    Perry, S.W.2    Reynolds, H.M.3
  • 42
    • 78349307902 scopus 로고    scopus 로고
    • Regulation of oxidative stress by pituitary adenylate cyclase-activating polypeptide (PACAP) mediated by PACAP receptor
    • COI: 1:CAS:528:DC%2BC3cXht1yktbzN, PID: 20387010
    • Ohtaki H, Satoh A, Nakamachi T et al (2010) Regulation of oxidative stress by pituitary adenylate cyclase-activating polypeptide (PACAP) mediated by PACAP receptor. J Mol Neurosci 42:397–403
    • (2010) J Mol Neurosci , vol.42 , pp. 397-403
    • Ohtaki, H.1    Satoh, A.2    Nakamachi, T.3
  • 43
    • 3442882468 scopus 로고    scopus 로고
    • Effects of apolipoprotein E on the human immunodeficiency virus protein Tat in neuronal cultures and synaptosomes
    • COI: 1:CAS:528:DC%2BD2cXmtlKmtbc%3D, PID: 15264223
    • Pocernich CB, Sultana R, Hone E et al (2004) Effects of apolipoprotein E on the human immunodeficiency virus protein Tat in neuronal cultures and synaptosomes. J Neurosci Res 77:532–539
    • (2004) J Neurosci Res , vol.77 , pp. 532-539
    • Pocernich, C.B.1    Sultana, R.2    Hone, E.3
  • 44
    • 27744450714 scopus 로고    scopus 로고
    • HIV-dementia, Tat-induced oxidative stress, and antioxidant therapeutic considerations
    • COI: 1:CAS:528:DC%2BD2MXht1SksrnL, PID: 15890409
    • Pocernich CB, Sultana R, Mohmmad-Abdul H, Nath A, Butterfield DA (2005) HIV-dementia, Tat-induced oxidative stress, and antioxidant therapeutic considerations. Brain Res Brain Res Rev 50:14–26
    • (2005) Brain Res Brain Res Rev , vol.50 , pp. 14-26
    • Pocernich, C.B.1    Sultana, R.2    Mohmmad-Abdul, H.3    Nath, A.4    Butterfield, D.A.5
  • 45
    • 0034883795 scopus 로고    scopus 로고
    • Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism
    • COI: 1:CAS:528:DC%2BD3MXmt1egsbs%3D, PID: 11520908
    • Ramirez SH, Sanchez JF, Dimitri CA, Gelbard HA, Dewhurst S, Maggirwar SB (2001) Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism. J Neurochem 78:874–889
    • (2001) J Neurochem , vol.78 , pp. 874-889
    • Ramirez, S.H.1    Sanchez, J.F.2    Dimitri, C.A.3    Gelbard, H.A.4    Dewhurst, S.5    Maggirwar, S.B.6
  • 46
    • 79958167912 scopus 로고    scopus 로고
    • Review on the protective effects of PACAP in models of neurodegenerative diseases in vitro and in vivo
    • COI: 1:CAS:528:DC%2BC3MXmvFGgtr8%3D, PID: 21524257
    • Reglodi D, Kiss P, Lubics A, Tamas A (2011) Review on the protective effects of PACAP in models of neurodegenerative diseases in vitro and in vivo. Curr Pharm Des 17:962–972
    • (2011) Curr Pharm Des , vol.17 , pp. 962-972
    • Reglodi, D.1    Kiss, P.2    Lubics, A.3    Tamas, A.4
  • 47
    • 67651005601 scopus 로고    scopus 로고
    • RANTES release contributes to the protective action of PACAP38 against sodium nitroprusside in cortical neurons
    • COI: 1:CAS:528:DC%2BD1MXptVemtrw%3D, PID: 19497618
    • Sanchez A, Tripathy D, Grammas P (2009a) RANTES release contributes to the protective action of PACAP38 against sodium nitroprusside in cortical neurons. Neuropeptides 43:315–320
    • (2009) Neuropeptides , vol.43 , pp. 315-320
    • Sanchez, A.1    Tripathy, D.2    Grammas, P.3
  • 48
    • 57249094333 scopus 로고    scopus 로고
    • PACAP38 protects rat cortical neurons against the neurotoxicity evoked by sodium nitroprusside and thrombin
    • COI: 1:CAS:528:DC%2BD1cXhsV2lur7F, PID: 18682263
    • Sanchez A, Rao HV, Grammas P (2009b) PACAP38 protects rat cortical neurons against the neurotoxicity evoked by sodium nitroprusside and thrombin. Regul Pept 152:33–40
    • (2009) Regul Pept , vol.152 , pp. 33-40
    • Sanchez, A.1    Rao, H.V.2    Grammas, P.3
  • 49
    • 84881611195 scopus 로고    scopus 로고
    • Motile axonal mitochondria contribute to the variability of presynaptic strength
    • COI: 1:CAS:528:DC%2BC3sXhtFOrtrbO, PID: 23891000
    • Sun T, Qiao H, Pan PY, Chen Y, Sheng ZH (2013) Motile axonal mitochondria contribute to the variability of presynaptic strength. Cell Rep 4:413–419
    • (2013) Cell Rep , vol.4 , pp. 413-419
    • Sun, T.1    Qiao, H.2    Pan, P.Y.3    Chen, Y.4    Sheng, Z.H.5
  • 50
    • 0036459990 scopus 로고    scopus 로고
    • PACAP protects cerebellar granule neurons against oxidative stress-induced apoptosis
    • COI: 1:STN:280:DC%2BD38zitlOltA%3D%3D, PID: 12028355
    • Vaudry D, Pamantung TF, Basille M et al (2002) PACAP protects cerebellar granule neurons against oxidative stress-induced apoptosis. Eur J Neurosci 15:1451–1460
    • (2002) Eur J Neurosci , vol.15 , pp. 1451-1460
    • Vaudry, D.1    Pamantung, T.F.2    Basille, M.3
  • 51
    • 70349922918 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery
    • COI: 1:CAS:528:DC%2BC3cXhsVWmu7vK, PID: 19805477
    • Vaudry D, Falluel-Morel A, Bourgault S et al (2009) Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev 61:283–357
    • (2009) Pharmacol Rev , vol.61 , pp. 283-357
    • Vaudry, D.1    Falluel-Morel, A.2    Bourgault, S.3
  • 52
    • 84861199913 scopus 로고    scopus 로고
    • Accumulation of nuclear and mitochondrial DNA damage in the frontal cortex cells of patients with HIV-associated neurocognitive disorders
    • COI: 1:CAS:528:DC%2BC38Xntlaisr0%3D, PID: 22554480
    • Zhang Y, Wang M, Li H et al (2012) Accumulation of nuclear and mitochondrial DNA damage in the frontal cortex cells of patients with HIV-associated neurocognitive disorders. Brain Res 1458:1–11
    • (2012) Brain Res , vol.1458 , pp. 1-11
    • Zhang, Y.1    Wang, M.2    Li, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.