HIV-1 tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: Implications for HIV-associated neurocognitive disorders

Journal of Neuroscience

Volumn 35, Issue 5, 2015, Pages 1921-1938

  Fields, Jerel ^a   Dumaop, Wilmar ^a   Elueteri, Simona ^a   Campos, Sofia ^a   Serger, Elisabeth ^a   Trejo, Margarita ^a   Kosberg, Kori ^a   Adame, Anthony ^a   Spencer, Brian ^a   Rockenstein, Edward ^a   He, Johnny J ^b   Masliah, Eliezer ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

Autophagy; HIV; LAMP2A; Tat

Indexed keywords

3 METHYLADENINE; BAFILOMYCIN A1; BECLIN 1; GREEN FLUORESCENT PROTEIN; LIGHT CHAIN BETA 2; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MICROTUBULE ASSOCIATED PROTEIN 1; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; PROTEIN BINDING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY LABELING; ANTIBODY RESPONSE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DISEASE ASSOCIATION; ELECTRON MICROSCOPY; GENE FUSION; GENE SILENCING; HIV ASSOCIATED DEMENTIA; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LYSOSOME; NERVE CELL; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SEQUESTOSOME; ANIMAL; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; MOUSE; PHAGOSOME; TUMOR CELL LINE;

AIDS DEMENTIA COMPLEX; ANIMALS; AUTOPHAGY; CELL LINE, TUMOR; CELLS, CULTURED; HIV-1; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 2; LYSOSOMES; MICE; NEURONS; PHAGOSOMES; PROTEIN BINDING; RATS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 84922390366     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3207-14.2015     Document Type: Article

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