-
1
-
-
0015319592
-
The biological clock: The mitochondria?
-
[1] Harman D., The biological clock: the mitochondria?, J. Am. Geriat Soc. 20 (1972) 145-147.
-
(1972)
J. Am. Geriat Soc.
, vol.20
, pp. 145-147
-
-
Harman, D.1
-
2
-
-
0003138331
-
Theoretical and experimental support for an 'oxygen radical-mitochondrial injury hypothesis of cell aging'
-
Johnson Jr. J.E., Walford R., Harman D., Miquel J. (Eds.), A.R. Liss, New York, NY
-
[2] Miquel J., Fleming J.E., Theoretical and experimental support for an 'oxygen radical-mitochondrial injury hypothesis of cell aging', in: Johnson Jr. J.E., Walford R., Harman D., Miquel J. (Eds.), Free radicals, aging and degenerative diseases, A.R. Liss, New York, NY, 1986, pp. 51-74
-
(1986)
Free Radicals, Aging and Degenerative Diseases
, pp. 51-74
-
-
Miquel, J.1
Fleming, J.E.2
-
3
-
-
0024541837
-
Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
-
[3] Linnane A.W., Marzuki S., Ozawa T., Tanaka M., Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases, Lancet i (1989) 642-645.
-
(1989)
Lancet
, vol.1
, pp. 642-645
-
-
Linnane, A.W.1
Marzuki, S.2
Ozawa, T.3
Tanaka, M.4
-
4
-
-
0030897739
-
Genetic and functional changes in mitochondria associated with aging
-
[4] Ozawa T., Genetic and functional changes in mitochondria associated with aging, Physiol. Rev. 77 (1997) 425-464.
-
(1997)
Physiol. Rev.
, vol.77
, pp. 425-464
-
-
Ozawa, T.1
-
5
-
-
0031916984
-
The free radical theory of aging matures
-
[5] Beckman K.B., Ames B.N., The free radical theory of aging matures, Physiol. Rev. 78 (1998) 547-581.
-
(1998)
Physiol. Rev.
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
6
-
-
0002079547
-
Age-linked changes in the genotype and phenotype of mitochondria
-
Papa S., Guerrieri F., Tager J. (Eds.), Plenum Publishing Company Ltd., London, in press
-
[6] Gadaleta M.N., Kadenbach B., Lezza A., Reith A., Cantatore P., Papa S., Age-linked changes in the genotype and phenotype of mitochondria, in: Papa S., Guerrieri F., Tager J. (Eds.), Frontiers of cellular bioenergetics: molecular biology, biochemistry, and physiopathology, Plenum Publishing Company Ltd., London, 1998, in press.
-
(1998)
Frontiers of Cellular Bioenergetics: Molecular Biology, Biochemistry, and Physiopathology
-
-
Gadaleta, M.N.1
Kadenbach, B.2
Lezza, A.3
Reith, A.4
Cantatore, P.5
Papa, S.6
-
7
-
-
2542505678
-
Oxidative stress and mitochondrial DNA mutations in human aging
-
[7] Wei Y.H., Oxidative stress and mitochondrial DNA mutations in human aging, Proc. Soc. Exp. Biol. Med. 217 (1998) 53-63.
-
(1998)
Proc. Soc. Exp. Biol. Med.
, vol.217
, pp. 53-63
-
-
Wei, Y.H.1
-
8
-
-
0023883150
-
Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies
-
[8] Holt I.J., Harding A.E., Morgan-Hughes J.A., Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies, Nature 331 (1988) 717-719.
-
(1988)
Nature
, vol.331
, pp. 717-719
-
-
Holt, I.J.1
Harding, A.E.2
Morgan-Hughes, J.A.3
-
9
-
-
0024242545
-
Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy
-
[9] Wallace D.C., Singh G., Lott M.T., Hodge J.A., Schurr T.G., Lezza A.M.S., Epsas L.J., Nikoskelainen E.K., Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy, Science 242 (1988) 1427-1430.
-
(1988)
Science
, vol.242
, pp. 1427-1430
-
-
Wallace, D.C.1
Singh, G.2
Lott, M.T.3
Hodge, J.A.4
Schurr, T.G.5
Lezza, A.M.S.6
Epsas, L.J.7
Nikoskelainen, E.K.8
-
10
-
-
0024596946
-
A direct repeat is a hotspot for large-scale deletion of human mitochondrial DNA
-
[10] Schon E.A., Rizzuto R., Moraes C.T., Nakase H., Zeviani M., Di Mauro S., A direct repeat is a hotspot for large-scale deletion of human mitochondrial DNA, Science 244 (1989) 346-349.
-
(1989)
Science
, vol.244
, pp. 346-349
-
-
Schon, E.A.1
Rizzuto, R.2
Moraes, C.T.3
Nakase, H.4
Zeviani, M.5
Di Mauro, S.6
-
11
-
-
0025674177
-
Detection of a specific mitochondrial DNA deletion in tissues of older humans
-
[11] Cortopassi G.A., Arnheim N., Detection of a specific mitochondrial DNA deletion in tissues of older humans, Nucleic Acids Res. 18 (1990) 6927-6933.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 6927-6933
-
-
Cortopassi, G.A.1
Arnheim, N.2
-
12
-
-
0024580556
-
Decline in skeletal muscle mitochondrial respiratory chain function: Possible factor in aging
-
[12] Trounce I., Byrne E., Marzuki S., Decline in skeletal muscle mitochondrial respiratory chain function: possible factor in aging, Lancet i (1989) 637-639.
-
(1989)
Lancet
, vol.1
, pp. 637-639
-
-
Trounce, I.1
Byrne, E.2
Marzuki, S.3
-
13
-
-
0030581498
-
Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications
-
[13] Papa S., Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications, Biochim. Biophys. Acta 1276 (1996) 87-105.
-
(1996)
Biochim. Biophys. Acta
, vol.1276
, pp. 87-105
-
-
Papa, S.1
-
14
-
-
0025115244
-
Reduced transcription of mitochondrial DNA in the senescent rat. Tissue dependence and effect of acetyl-L-carnitine
-
[14] Gadaleta M.N., Petruzzella V., Renis M., Fracasso F., Cantatore P., Reduced transcription of mitochondrial DNA in the senescent rat. Tissue dependence and effect of acetyl-L-carnitine, Eur. J. Biochem. 187 (1990) 501-506.
-
(1990)
Eur. J. Biochem.
, vol.187
, pp. 501-506
-
-
Gadaleta, M.N.1
Petruzzella, V.2
Renis, M.3
Fracasso, F.4
Cantatore, P.5
-
15
-
-
0009530877
-
Reduced mitochondrial DNA transcription in two brain regions of senescent rat: Effect of acetyl-L-carnitine
-
Quagliariello E. et al. (Eds.), Elsevier, Amsterdam, the Nederlands
-
[15] Gadaleta M.N., Petruzzella V., Renis M., Fracasso E, Cautatore P., Reduced mitochondrial DNA transcription in two brain regions of senescent rat: effect of acetyl-L-carnitine, in: Quagliariello E. et al. (Eds.), Structure, function and biogenesis of energy transfer systems, Elsevier, Amsterdam, the Nederlands, 1990, pp. 135-138
-
(1990)
Structure, Function and Biogenesis of Energy Transfer Systems
, pp. 135-138
-
-
Gadaleta, M.N.1
Petruzzella, V.2
Renis, M.3
Fracasso, E.4
Cautatore, P.5
-
16
-
-
0028270618
-
Mitochondrial DNA transcription and translation in aged rat: Effect of acetyl-L-carnitine
-
[16] Gadaleta M.N., Petruzzella V., Daddabbo L., Olivieri C., Fracasso F., Loguercio Polosa P., Cantatore P., Mitochondrial DNA transcription and translation in aged rat: effect of acetyl-L-carnitine, Ann. N.Y. Acad. Sci. 717 (1994) 150-160.
-
(1994)
Ann. N.Y. Acad. Sci.
, vol.717
, pp. 150-160
-
-
Gadaleta, M.N.1
Petruzzella, V.2
Daddabbo, L.3
Olivieri, C.4
Fracasso, F.5
Loguercio Polosa, P.6
Cantatore, P.7
-
17
-
-
0022475988
-
Entry of acetyl-L-carnitine into biosynthetic pathways
-
[17] Farrell S., Vogel J., Bieter L.L., Entry of acetyl-L-carnitine into biosynthetic pathways, Biochim. Biophys. Acta 876 (1986) 175-177.
-
(1986)
Biochim. Biophys. Acta
, vol.876
, pp. 175-177
-
-
Farrell, S.1
Vogel, J.2
Bieter, L.L.3
-
18
-
-
0025777672
-
Reduced synthesis of mtRNA in isolated mitochondria of senescent rat brain
-
[18] Fernandez-Silva P., Petruzzella V., Fracasso F., Gadaleta M.N., Cantatore P., Reduced synthesis of mtRNA in isolated mitochondria of senescent rat brain, Biochem. Biophys. Res. Commun. 176 (1991) 645-653.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.176
, pp. 645-653
-
-
Fernandez-Silva, P.1
Petruzzella, V.2
Fracasso, F.3
Gadaleta, M.N.4
Cantatore, P.5
-
19
-
-
0026712284
-
Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rat
-
[19] Gadaleta M.N., Rainaldi G., Lezza A.M.S., Milella F., Fracasso F., Cantatore P., Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rat, Mutat. Res. 275 (1992) 181-193.
-
(1992)
Mutat. Res.
, vol.275
, pp. 181-193
-
-
Gadaleta, M.N.1
Rainaldi, G.2
Lezza, A.M.S.3
Milella, F.4
Fracasso, F.5
Cantatore, P.6
-
20
-
-
0027058596
-
Accumulation of mtDNA defects and changes in mtDNA content in mouse and rat tissues with aging
-
[20] Pikò L., Accumulation of mtDNA defects and changes in mtDNA content in mouse and rat tissues with aging, Ann. N.Y. Acad. Sci. 663 (1992) 450-452.
-
(1992)
Ann. N.Y. Acad. Sci.
, vol.663
, pp. 450-452
-
-
Pikò, L.1
-
21
-
-
0009542729
-
Structure and expression of mitochondrial DNA in aging rat: DNA deletions and protein synthesis
-
Palmieri F. et al. (Eds.), Elsevier Science B.V., Amsterdam
-
[21] Gadaleta M.N., Rainaldi G., Lezza A.M.S., Marangi L.C., Milella F., Daddabbo L., Fracasso F., Loguercio Polosa P., Cautatore P., Structure and expression of mitochondrial DNA in aging rat: DNA deletions and protein synthesis, in: Palmieri F. et al. (Eds.), Progress in Cell Research, Elsevier Science B.V., Amsterdam, 5, 1995, 231-235.
-
(1995)
Progress in Cell Research
, vol.5
, pp. 231-235
-
-
Gadaleta, M.N.1
Rainaldi, G.2
Lezza, A.M.S.3
Marangi, L.C.4
Milella, F.5
Daddabbo, L.6
Fracasso, F.7
Loguercio Polosa, P.8
Cautatore, P.9
-
22
-
-
0031557655
-
Quantification of wild-type mitochondrial DNA and its 4.8-kb deletion in rat organs
-
[22] Filser N., Margue C., Richter C., Quantification of wild-type mitochondrial DNA and its 4.8-kb deletion in rat organs, Biochem. Biophys. Res. Commun. 233 (1997) 102-107.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.233
, pp. 102-107
-
-
Filser, N.1
Margue, C.2
Richter, C.3
-
23
-
-
0032536886
-
Quantitation of age-related mitochondrial DNA deletions in rat tissues shows that their pattern of accumulation differs from that of humans
-
[23] Yowe D.L., Ames B.N., Quantitation of age-related mitochondrial DNA deletions in rat tissues shows that their pattern of accumulation differs from that of humans, Gene 209 (1998) 23-30.
-
(1998)
Gene
, vol.209
, pp. 23-30
-
-
Yowe, D.L.1
Ames, B.N.2
-
24
-
-
0030599207
-
Rearrangements in the shorter arc of rat mitochondrial DNA involving the region of the heavy and light strand promoters
-
[24] Gudikote J.P., Van Tuyle G.C., Rearrangements in the shorter arc of rat mitochondrial DNA involving the region of the heavy and light strand promoters, Mutat. Res. 356 (1996) 275-286.
-
(1996)
Mutat. Res.
, vol.356
, pp. 275-286
-
-
Gudikote, J.P.1
Van Tuyle, G.C.2
-
25
-
-
0030067344
-
Multiple, large deletions in rat mitochondrial DNA: Evidence for a major hot spot
-
[25] VanTuyle G.C., Gudikote J.P., Hurt V.R., Miller B.B., Moore C.A., Multiple, large deletions in rat mitochondrial DNA: evidence for a major hot spot, Mutat. Res. 349 (1996) 95-107.
-
(1996)
Mutat. Res.
, vol.349
, pp. 95-107
-
-
VanTuyle, G.C.1
Gudikote, J.P.2
Hurt, V.R.3
Miller, B.B.4
Moore, C.A.5
-
26
-
-
0027016008
-
Growing old: The most common mitochondrial disease of all?
-
[26] Harding A.E., Growing old: the most common mitochondrial disease of all?, Nature Genet 2 (1992) 251-252.
-
(1992)
Nature Genet
, vol.2
, pp. 251-252
-
-
Harding, A.E.1
-
27
-
-
0020681322
-
Changes in D-loop frequency and superhelicity among the mitochondrial DNA molecules in relation to organelle biogenesis in oocytes of Xenopus laevis
-
[27] Callen J.C., Tourte M., Dennebouy N., Monoulou J.C., Changes in D-loop frequency and superhelicity among the mitochondrial DNA molecules in relation to organelle biogenesis in oocytes of Xenopus laevis, Exp. Cell Res. 143 (1983) 115-125.
-
(1983)
Exp. Cell Res.
, vol.143
, pp. 115-125
-
-
Callen, J.C.1
Tourte, M.2
Dennebouy, N.3
Monoulou, J.C.4
-
28
-
-
0025175704
-
Mitochondrial DNA structure and expression in specialized subtypes of mammalian striated muscle
-
[28] Annex B.H., Williams R.S., Mitochondrial DNA structure and expression in specialized subtypes of mammalian striated muscle, Mol. Cell Biol. 10 (1990) 5671-5678.
-
(1990)
Mol. Cell Biol.
, vol.10
, pp. 5671-5678
-
-
Annex, B.H.1
Williams, R.S.2
-
29
-
-
0029065190
-
Decrease of D-loop frequency in heart and cerebral hemispheres mitochondrial DNA of aged rat
-
[29] Petruzzella V., Fracasso F., Gadaleta M.N., Cantatore P., Decrease of D-loop frequency in heart and cerebral hemispheres mitochondrial DNA of aged rat, Mol. Chem. Neuropathol. 24 (1995) 193-202.
-
(1995)
Mol. Chem. Neuropathol.
, vol.24
, pp. 193-202
-
-
Petruzzella, V.1
Fracasso, F.2
Gadaleta, M.N.3
Cantatore, P.4
-
30
-
-
0017394985
-
Complex forms and replicative intermediates of mitochondrial DNA in tissues from adult and senescent mice
-
[30] Pikò L., Matsumoto L., Complex forms and replicative intermediates of mitochondrial DNA in tissues from adult and senescent mice, Nucleic Acids Res. 4 (1977) 1301-1314.
-
(1977)
Nucleic Acids Res.
, vol.4
, pp. 1301-1314
-
-
Pikò, L.1
Matsumoto, L.2
-
31
-
-
0021282458
-
Structural and replicative forms of mitochondrial DNA in tissues from adult and senescent Balb/c mice and Fisher 344 rats
-
[31] Pikò L., Bulpitt K.J., Meyer R., Structural and replicative forms of mitochondrial DNA in tissues from adult and senescent Balb/c mice and Fisher 344 rats, Mech. Aging Dev. 26 (1984) 113-131.
-
(1984)
Mech. Aging Dev.
, vol.26
, pp. 113-131
-
-
Pikò, L.1
Bulpitt, K.J.2
Meyer, R.3
-
32
-
-
0023911501
-
Preference of human mitochondrial RNA polymerase for superhelical templates with mitochondrial promoters
-
[32] Buzan J.M., Low R.L., Preference of human mitochondrial RNA polymerase for superhelical templates with mitochondrial promoters, Biochem. Biophys. Res. Commun. 152 (1988) 22-29.
-
(1988)
Biochem. Biophys. Res. Commun.
, vol.152
, pp. 22-29
-
-
Buzan, J.M.1
Low, R.L.2
-
33
-
-
0024348735
-
Effect of DNA conformation on the transcription of mitochondrial DNA
-
[33] Barat-Gueride M., Dufresne C., Rickwood D., Effect of DNA conformation on the transcription of mitochondrial DNA, Eur. J. Biochem. 183 (1989) 297-302.
-
(1989)
Eur. J. Biochem.
, vol.183
, pp. 297-302
-
-
Barat-Gueride, M.1
Dufresne, C.2
Rickwood, D.3
-
34
-
-
0013799683
-
Stimulation of oxidation of mitochondrial fatty acids and of acetate by acetylcarnitine
-
[34] Siliprandi N., Siliprandi D., Ciman M., Stimulation of oxidation of mitochondrial fatty acids and of acetate by acetylcarnitine, Biochem. J. 96 (1965) 777-780.
-
(1965)
Biochem. J.
, vol.96
, pp. 777-780
-
-
Siliprandi, N.1
Siliprandi, D.2
Ciman, M.3
-
35
-
-
0027244097
-
Mitochondrial DNA remains intact during drosophila aging, but the levels of mitochondrial transcripts are significantly reduced
-
[35] Calleja M., Peña P., Ugalde C., Ferreiro C., Marco R., Garesse R., Mitochondrial DNA remains intact during Drosophila aging, but the levels of mitochondrial transcripts are significantly reduced, J. Biol. Chem. 268 (1993) 18891-18897.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 18891-18897
-
-
Calleja, M.1
Peña, P.2
Ugalde, C.3
Ferreiro, C.4
Marco, R.5
Garesse, R.6
-
36
-
-
0025862356
-
Distinctive pattern and translational control of mitochondrial protein synthesis in rat brain synaptic endings
-
[36] Loguercio Polosa P., Attardi G., Distinctive pattern and translational control of mitochondrial protein synthesis in rat brain synaptic endings, J. Biol. Chem. 266 (1991) 10011-10017.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 10011-10017
-
-
Loguercio Polosa, P.1
Attardi, G.2
-
37
-
-
0029603582
-
Age-associated changes of mitochondrial translation and respiratory function in mouse brain
-
[37] Takai D., Inoue K., Shisa H., Kagawa Y., Hayasbi J.I., Age-associated changes of mitochondrial translation and respiratory function in mouse brain, Biochem. Biophys. Res. Commun. 217 (1995) 668-674.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.217
, pp. 668-674
-
-
Takai, D.1
Inoue, K.2
Shisa, H.3
Kagawa, Y.4
Hayasbi, J.I.5
-
38
-
-
0025477126
-
Biogenesis and assembly of the mitochondrial respiratory chain: Structural, genetic and pathological aspects
-
[38] Attardi G., Chomyn A., King M.P., Kruse B., Loguercio Polosa P., NarasimhanMurdter N., Biogenesis and assembly of the mitochondrial respiratory chain: structural, genetic and pathological aspects, Biochem. Soc. Trans. 18 (1990) 509-513.
-
(1990)
Biochem. Soc. Trans.
, vol.18
, pp. 509-513
-
-
Attardi, G.1
Chomyn, A.2
King, M.P.3
Kruse, B.4
Loguercio Polosa, P.5
NarasimhanMurdter, N.6
-
39
-
-
0026667049
-
Age-dependent changes in the mitochondrial F0F1 ATP synthase
-
[39] Guerrieri F., Capozza G., Kalous M., Zanotti F., Drahota Z., Papa S., Age-dependent changes in the mitochondrial F0F1 ATP synthase, Arch. Gerontol. Geriatr. 14 (1992) 299-308.
-
(1992)
Arch. Gerontol. Geriatr.
, vol.14
, pp. 299-308
-
-
Guerrieri, F.1
Capozza, G.2
Kalous, M.3
Zanotti, F.4
Drahota, Z.5
Papa, S.6
-
40
-
-
0030454974
-
Presence of a DNA-4236 bp deletion and 8-hydroxy-deoxyguanosine in mouse cardiac mitochondrial DNA during aging
-
[40] Muscari C., Giaccari A., Stefanelli C., Viticchi C., Giordano E., Guarnieri C., Caldarera C.M., Presence of a DNA-4236 bp deletion and 8-hydroxy-deoxyguanosine in mouse cardiac mitochondrial DNA during aging, Aging Clin. Exp. Res. 8 (1996) 429-433.
-
(1996)
Aging Clin. Exp. Res.
, vol.8
, pp. 429-433
-
-
Muscari, C.1
Giaccari, A.2
Stefanelli, C.3
Viticchi, C.4
Giordano, E.5
Guarnieri, C.6
Caldarera, C.M.7
-
41
-
-
0024448458
-
Human cells lacking mtDNA: Repopulation with exogenous mitochondria by complementation
-
[41] King M.P., Attardi G., Human cells lacking mtDNA: Repopulation with exogenous mitochondria by complementation, Science 246 (1989) 500-503.
-
(1989)
Science
, vol.246
, pp. 500-503
-
-
King, M.P.1
Attardi, G.2
-
42
-
-
0029064633
-
Intramitochondrial protein synthesis is regulated by matrix adenine nucleotide content and requires calcium
-
[42] Joyal J.L., Hagen T, Aprille J.R., Intramitochondrial protein synthesis is regulated by matrix adenine nucleotide content and requires calcium, Arch. Biochem. Biophys. 319 (1995) 322-330.
-
(1995)
Arch. Biochem. Biophys.
, vol.319
, pp. 322-330
-
-
Joyal, J.L.1
Hagen, T.2
Aprille, J.R.3
-
43
-
-
0029974275
-
The synthesis of mRNA in isolated mitochondria can be maintained for several hours and is inhibited by high levels of ATP
-
[43] Enriquez J.A., Fernandez-Silva P., Perez-Martos A., Lopez-Perez M.J., Montoya J., The synthesis of mRNA in isolated mitochondria can be maintained for several hours and is inhibited by high levels of ATP, Eur. J. Biochem. 237 (1996) 601-610.
-
(1996)
Eur. J. Biochem.
, vol.237
, pp. 601-610
-
-
Enriquez, J.A.1
Fernandez-Silva, P.2
Perez-Martos, A.3
Lopez-Perez, M.J.4
Montoya, J.5
-
44
-
-
0026602789
-
In vivo effect of acetyl-L-carnitine on succinate oxidation, adenine nucleotide pool and lipid composition of synaptic and non-synaptic mitochondria from cerebral hemispheres of senescent rats
-
[44] Petruzzella V., Baggetto L.G., Penin F., Cafagna F., Ruggiero F.M., Cantatore P., Gadaleta M.N., In vivo effect of acetyl-L-carnitine on succinate oxidation, adenine nucleotide pool and lipid composition of synaptic and non-synaptic mitochondria from cerebral hemispheres of senescent rats, Arch. Gerontol. Geriatr. 14 (1992) 131-144.
-
(1992)
Arch. Gerontol. Geriatr.
, vol.14
, pp. 131-144
-
-
Petruzzella, V.1
Baggetto, L.G.2
Penin, F.3
Cafagna, F.4
Ruggiero, F.M.5
Cantatore, P.6
Gadaleta, M.N.7
-
45
-
-
0026501632
-
The effect of aging and acetyl-L-carnitine on the activity of the phosphate carrier and on the phospholipid composition in rat heart mitochondria
-
[45] Paradies G., Ruggiero F.M., Gadaleta M.N., Quagliariello E., The effect of aging and acetyl-L-carnitine on the activity of the phosphate carrier and on the phospholipid composition in rat heart mitochondria, Biochim. Biophys. Acta 1103 (1992) 324-326.
-
(1992)
Biochim. Biophys. Acta
, vol.1103
, pp. 324-326
-
-
Paradies, G.1
Ruggiero, F.M.2
Gadaleta, M.N.3
Quagliariello, E.4
-
46
-
-
0028025440
-
Effect of aging and acetyl-L-carnitine on the activity of cytochrome oxidase and adenine nucleotide translocase in rat heart mitochondria
-
[46] Paradies G., Ruggiero F.M., Petrosillo G., Gadaleta M.N., Quagliariello E., Effect of aging and acetyl-L-carnitine on the activity of cytochrome oxidase and adenine nucleotide translocase in rat heart mitochondria, FEBS Lett. 350 (1994) 213-215.
-
(1994)
FEBS Lett.
, vol.350
, pp. 213-215
-
-
Paradies, G.1
Ruggiero, F.M.2
Petrosillo, G.3
Gadaleta, M.N.4
Quagliariello, E.5
-
47
-
-
0029610276
-
Carnitine acylcarnitine translocase activity in cardiac mitochondria from aged rats: The effect of acetyl-L-carnitine
-
[47] Paradies G., Ruggiero F.M., Petrosillo G., Gadaleta M.N., Quagliariello E., Carnitine acylcarnitine translocase activity in cardiac mitochondria from aged rats: the effect of acetyl-L-carnitine, Mech. Ageing Dev. 84 (1995) 103-112.
-
(1995)
Mech. Ageing Dev.
, vol.84
, pp. 103-112
-
-
Paradies, G.1
Ruggiero, F.M.2
Petrosillo, G.3
Gadaleta, M.N.4
Quagliariello, E.5
-
48
-
-
0030992498
-
Age-dependent decline in the cytochrome c oxidase activity in rat heart mitochondria: Role of cardiolipin
-
[48] Paradies G., Ruggiero F.M., Petrosillo G., Quagliariello E., Age-dependent decline in the cytochrome c oxidase activity in rat heart mitochondria: role of cardiolipin, FEBS Lett. 406 (1997) 136-138.
-
(1997)
FEBS Lett.
, vol.406
, pp. 136-138
-
-
Paradies, G.1
Ruggiero, F.M.2
Petrosillo, G.3
Quagliariello, E.4
-
49
-
-
0025026205
-
1H NMR spectroscopy
-
1H NMR spectroscopy, Brain Res. 526 (1990) 108-112.
-
(1990)
Brain Res.
, vol.526
, pp. 108-112
-
-
Aureli, T.1
Miccheli, A.2
Ricciolini, R.3
DiCocco, M.E.4
Ramacci, M.T.5
Angelucci, L.6
Ghirardi, O.7
Conti, F.8
-
50
-
-
0025240059
-
Levels of carnitines in brain and other tissues of rats of different ages: Effect of acetyl-L-carnitine administration
-
[50] Maccari F., Arseni A., Chiodi P., Ramacci M.T., Angelucci L., Levels of carnitines in brain and other tissues of rats of different ages: effect of acetyl-L-carnitine administration, Exp. Gerontol 25 (1990) 127-134.
-
(1990)
Exp. Gerontol
, vol.25
, pp. 127-134
-
-
Maccari, F.1
Arseni, A.2
Chiodi, P.3
Ramacci, M.T.4
Angelucci, L.5
-
51
-
-
0030702781
-
Mitochondrial oxygen radical formation during reductive and oxidative stress to intact hepatocytes
-
[51] Lemasters J.J., Nieminen A.L., Mitochondrial oxygen radical formation during reductive and oxidative stress to intact hepatocytes, Biosci. Rep. 17 (1997) 281-291.
-
(1997)
Biosci. Rep.
, vol.17
, pp. 281-291
-
-
Lemasters, J.J.1
Nieminen, A.L.2
-
52
-
-
0030809576
-
Reactive oxygen species, mitochondria, apoptosis and aging
-
[52] Papa S., Skulachev V.P., Reactive oxygen species, mitochondria, apoptosis and aging, Mol. Cell Biochem. 174 (1997) 305-319.
-
(1997)
Mol. Cell Biochem.
, vol.174
, pp. 305-319
-
-
Papa, S.1
Skulachev, V.P.2
-
53
-
-
0030848374
-
Mitochondrial implication in accidental and programmed cell death: Apoptosis and necrosis
-
[53] Zamzami N., Hirsch T., Dallaporta B., Petit P.X., Kroemer G., Mitochondrial implication in accidental and programmed cell death: apoptosis and necrosis, J. Bioenerg. Biomembr. 29 (1997) 185-193.
-
(1997)
J. Bioenerg. Biomembr.
, vol.29
, pp. 185-193
-
-
Zamzami, N.1
Hirsch, T.2
Dallaporta, B.3
Petit, P.X.4
Kroemer, G.5
-
54
-
-
0028670384
-
Identification of genes induced during apoptosis in T lymphocytes
-
[54] Osborne B.A., Smith S.W., Liu Z.G., McLaughlin K.A., Grimm L., Schwartz L.M., Identification of genes induced during apoptosis in T lymphocytes, Immunol. Rev. 142 (1994) 301-320.
-
(1994)
Immunol. Rev.
, vol.142
, pp. 301-320
-
-
Osborne, B.A.1
Smith, S.W.2
Liu, Z.G.3
McLaughlin, K.A.4
Grimm, L.5
Schwartz, L.M.6
-
55
-
-
0028046038
-
Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40
-
[55] Vayssière J.L., Petit P.X., Risler Y., Mignotte B., Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40, Proc. Natl. Acad. Sci. USA 91 (1994) 11752-11756.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11752-11756
-
-
Vayssière, J.L.1
Petit, P.X.2
Risler, Y.3
Mignotte, B.4
-
56
-
-
0026728212
-
Progressive loss of cytochrome c oxidase in the human extraocular muscles in aging - A cytochemical-immunohistochemical study
-
[56] Müller-Höcher J., Schneiderbanger K., Stefani F.H., Kadenbach B., Progressive loss of cytochrome c oxidase in the human extraocular muscles in aging - a cytochemical-immunohistochemical study, Mutat. Res. 275 (1992) 115-124.
-
(1992)
Mutat. Res.
, vol.275
, pp. 115-124
-
-
Müller-Höcher, J.1
Schneiderbanger, K.2
Stefani, F.H.3
Kadenbach, B.4
-
57
-
-
0025324655
-
Age-dependent nerve cell loss in the brain of Sprague-Dawley rats: Effect of long term acetyl-L-carnitine treatment
-
[57] Napoleone P., Ferrante F., Ghirardi O., Ramacci M.T., Amenta F., Age-dependent nerve cell loss in the brain of Sprague-Dawley rats: effect of long term acetyl-L-carnitine treatment, Arch. Gerontol. Geriatr. 10 (1990) 173-185.
-
(1990)
Arch. Gerontol. Geriatr.
, vol.10
, pp. 173-185
-
-
Napoleone, P.1
Ferrante, F.2
Ghirardi, O.3
Ramacci, M.T.4
Amenta, F.5
-
58
-
-
0026755254
-
Effects of acetyl-L-carnitine on the survival of adult rat sensory neurons in primary cultures
-
[58] Formenti A., Arrigoni E., Sansone V., Arrigoni Martelli E., Mancia M., Effects of acetyl-L-carnitine on the survival of adult rat sensory neurons in primary cultures, Int. J. Dev. Neurosci. 10 (1992) 207-214.
-
(1992)
Int. J. Dev. Neurosci.
, vol.10
, pp. 207-214
-
-
Formenti, A.1
Arrigoni, E.2
Sansone, V.3
Arrigoni Martelli, E.4
Mancia, M.5
-
59
-
-
0030915483
-
Mitochondrial decay in hepatocytes from old rats: Membrane potential declines, heterogeneity and oxidants increase
-
[59] Hagen T.M., Yowe D.L., Bartholomew J.C., Wehr C.M., Do K.L., Park J.Y., Ames B.N., Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase, Proc. Natl. Acad. Sci. USA 94 (1997) 3064-3069.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3064-3069
-
-
Hagen, T.M.1
Yowe, D.L.2
Bartholomew, J.C.3
Wehr, C.M.4
Do, K.L.5
Park, J.Y.6
Ames, B.N.7
-
60
-
-
0032482999
-
Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity
-
[60] Hagen T.M., Ingersoll R.T., Wehr C.M., Lykkesfeldt J., Vinarsky V., Bartholomew J.C., Song M.H., Ames B.N., Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity, Proc. Natl. Acad. Sci. USA 95 (1998) 9562-9566.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9562-9566
-
-
Hagen, T.M.1
Ingersoll, R.T.2
Wehr, C.M.3
Lykkesfeldt, J.4
Vinarsky, V.5
Bartholomew, J.C.6
Song, M.H.7
Ames, B.N.8
-
62
-
-
0027724036
-
Control of gene expression by redox potential and the requirement for chloroplast and mitochondrial genomes
-
[62] Allen J.F., Control of gene expression by redox potential and the requirement for chloroplast and mitochondrial genomes, J. Theor. Biol. 165 (1993) 609-631.
-
(1993)
J. Theor. Biol.
, vol.165
, pp. 609-631
-
-
Allen, J.F.1
-
63
-
-
0000057543
-
Redox conditions specify the proteins synthesised by isolated chloroplasts and mitochondria
-
[63] Allen C.A., Håkansson G., Allen J.F., Redox conditions specify the proteins synthesised by isolated chloroplasts and mitochondria, Redox Rep. 1 (1995) 119-123.
-
(1995)
Redox Rep.
, vol.1
, pp. 119-123
-
-
Allen, C.A.1
Håkansson, G.2
Allen, J.F.3
-
64
-
-
0002827532
-
The role of bioenergetics and mitochondrial DNA mutations in aging and age-related diseases
-
Esser K., Martin G.M. (Eds.), John Wiley & Sons Ltd., Chichester, UK
-
[64] Wallace D.C., Bohr V.A., Cortopassi G., Kadenbach B., Linn S., Linnane A.W., Richter C., Shay J.W., The role of bioenergetics and mitochondrial DNA mutations in aging and age-related diseases, in: Esser K., Martin G.M. (Eds.), Molecular Aspects of Aging, John Wiley & Sons Ltd., Chichester, UK, 1995, pp. 199-225
-
(1995)
Molecular Aspects of Aging
, pp. 199-225
-
-
Wallace, D.C.1
Bohr, V.A.2
Cortopassi, G.3
Kadenbach, B.4
Linn, S.5
Linnane, A.W.6
Richter, C.7
Shay, J.W.8
-
65
-
-
0030582337
-
Down-regulation of nuclear binding activities of OXBOX-REBOX transcription factors during cellular senescence
-
[65] Lehtinen S.K., Rahkila P., Helenius M., Salminen A., Down-regulation of nuclear binding activities of OXBOX-REBOX transcription factors during cellular senescence, Biochem. Biophys. Res. Commun. 226 (1996) 403-406.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.226
, pp. 403-406
-
-
Lehtinen, S.K.1
Rahkila, P.2
Helenius, M.3
Salminen, A.4
-
66
-
-
85030363962
-
Acetyl-L-carnitine modulates histone H4 acetylation: Effects on gene expression and differentiation
-
Barcelona, 7-12 July, abstract
-
[66] Pisano C., Camerini B., Castorina M., Morabito E., Carbonetti A., Pucci A., Calvani M., Acetyl-L-carnitine modulates histone H4 acetylation: effects on gene expression and differentiation, 24th Meeting of the Federation of European Biochemical Society, FEBS ' 1996, Barcelona, 7-12 July, abstract p. 155.
-
(1996)
24th Meeting of the Federation of European Biochemical Society, FEBS ' 1996
, pp. 155
-
-
Pisano, C.1
Camerini, B.2
Castorina, M.3
Morabito, E.4
Carbonetti, A.5
Pucci, A.6
Calvani, M.7
-
67
-
-
0029985675
-
Nuclear respiratory factors and the pathways of nuclear-mitochondrial interaction
-
[67] Scarpulla R.C., Nuclear respiratory factors and the pathways of nuclear-mitochondrial interaction, Trends Cardiovasc. Med. 6 (1996) 39-45.
-
(1996)
Trends Cardiovasc. Med.
, vol.6
, pp. 39-45
-
-
Scarpulla, R.C.1
-
68
-
-
0026094952
-
Effect of thyroxine on the activity of mitochondrial cardiolipin synthase in rat liver
-
[68] Hostetler K. Y., Effect of thyroxine on the activity of mitochondrial cardiolipin synthase in rat liver, Biochim. Biophys. Acta 1086 (1991) 139-140.
-
(1991)
Biochim. Biophys. Acta
, vol.1086
, pp. 139-140
-
-
Hostetler, K.Y.1
-
69
-
-
0025604776
-
Acetyl-L-carnitine increases cytochrome oxidase subunit I mRNA content in hypothyroid rat liver
-
[69] Gadaleta M.N., Petruzzella V., Fracasso F., Fernandez-Silva P., Cantatore P., Acetyl-L-carnitine increases cytochrome oxidase subunit I mRNA content in hypothyroid rat liver, FEBS Lett. 277 (1990) 191-193.
-
(1990)
FEBS Lett.
, vol.277
, pp. 191-193
-
-
Gadaleta, M.N.1
Petruzzella, V.2
Fracasso, F.3
Fernandez-Silva, P.4
Cantatore, P.5
-
70
-
-
0020619917
-
Bioenergetics in aging
-
[70] Hansford R.G., Bioenergetics in aging, Biochim. Biophys. Acta 726 (1983) 41-80.
-
(1983)
Biochim. Biophys. Acta
, vol.726
, pp. 41-80
-
-
Hansford, R.G.1
-
71
-
-
0029553003
-
Human skeletal muscle mitochondria in aging: Lack of detectable morphological and enzymic defects
-
[71] Zucchini C., Pugnaloni A., Pallotti F., Solmi R., Crimi M., Castaldini C., Biagini G., Lenaz G., Human skeletal muscle mitochondria in aging: lack of detectable morphological and enzymic defects, Biochem. Mol. Biol. Int. 37 (1995) 607-616.
-
(1995)
Biochem. Mol. Biol. Int.
, vol.37
, pp. 607-616
-
-
Zucchini, C.1
Pugnaloni, A.2
Pallotti, F.3
Solmi, R.4
Crimi, M.5
Castaldini, C.6
Biagini, G.7
Lenaz, G.8
-
72
-
-
0030582656
-
Absence of relationship between the level of electron transport chain activities and aging in human skeletal muscle
-
[72] Barrientos A., Casademont J., Rötig A., Miró O., Urbano-Márquez A., Rustin P., Cardellach F., Absence of relationship between the level of electron transport chain activities and aging in human skeletal muscle, Biochem. Biophys. Res. Commun. 229 (1996) 536-539.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.229
, pp. 536-539
-
-
Barrientos, A.1
Casademont, J.2
Rötig, A.3
Miró, O.4
Urbano-Márquez, A.5
Rustin, P.6
Cardellach, F.7
-
73
-
-
0029741431
-
Evidence that specific mtDNA point mutations may not accumulate in skeletal muscle during normal human aging
-
[73] Pallotti F., Chen X., Bonilla E., Schon E.A., Evidence that specific mtDNA point mutations may not accumulate in skeletal muscle during normal human aging, Am. J. Hum. Genet. 59 (1996) 591-602.
-
(1996)
Am. J. Hum. Genet.
, vol.59
, pp. 591-602
-
-
Pallotti, F.1
Chen, X.2
Bonilla, E.3
Schon, E.A.4
-
74
-
-
0028109380
-
Correlation between mitochondrial DNA 4977-bp deletion and respiratory chain enzyme activities in aging human skeletal muscles
-
[74] Lezza A.M.S., Boffoli D., Scacco S., Cantatore P., Gadaleta M.N., Correlation between mitochondrial DNA 4977-bp deletion and respiratory chain enzyme activities in aging human skeletal muscles, Biochem. Biophys. Res. Commun. 205 (1994) 772-779.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.205
, pp. 772-779
-
-
Lezza, A.M.S.1
Boffoli, D.2
Scacco, S.3
Cantatore, P.4
Gadaleta, M.N.5
-
75
-
-
0014311556
-
Non-droplet ultrastructural demonstration of cytochrome c oxidase activity with a polymerasing osmiophilic reagent diaminobenzidine, (DAB)
-
[75] Seligman A.M., Karnovsky M.J., Wasserkrug H.L., Hanker J.S.V., Non-droplet ultrastructural demonstration of cytochrome c oxidase activity with a polymerasing osmiophilic reagent diaminobenzidine, (DAB), J. Cell Biol. 38 (1968) 1-14.
-
(1968)
J. Cell Biol.
, vol.38
, pp. 1-14
-
-
Seligman, A.M.1
Karnovsky, M.J.2
Wasserkrug, H.L.3
Hanker, J.S.V.4
-
76
-
-
0024328462
-
Mitochondrial DNA deletions in progressive external ophthalmoplegia and Kearns-Sayre syndrome
-
[76] Moraes C.T., Di Mauro S., Zeviani M., Lombes A., Shanske S., Miranda A.F., Nakase H., Bonilla E., Werneck L.C., Servidei S., Nonaka I., Koga Y., Spiro A.J., Brownell K.W., Schmidt B., Schotland D.L., Zupanc M., Devivo D.C., Schon E.A., Rowland L.P., Mitochondrial DNA deletions in progressive external ophthalmoplegia and Kearns-Sayre Syndrome, N. Engl. J. Med. 320 (1989) 1293-1299.
-
(1989)
N. Engl. J. Med.
, vol.320
, pp. 1293-1299
-
-
Moraes, C.T.1
Di Mauro, S.2
Zeviani, M.3
Lombes, A.4
Shanske, S.5
Miranda, A.F.6
Nakase, H.7
Bonilla, E.8
Werneck, L.C.9
Servidei, S.10
Nonaka, I.11
Koga, Y.12
Spiro, A.J.13
Brownell, K.W.14
Schmidt, B.15
Schotland, D.L.16
Zupanc, M.17
Devivo, D.C.18
Schon, E.A.19
Rowland, L.P.20
more..
-
77
-
-
0030830354
-
Mitochondrial DNA deletions in cculopharyngeal muscular dystrophy
-
[77] Lezza A.M.S., Cormio A., Gerardi P., Silvestri G., Servidei S., Serlenga L., Cantatore P., Gadaleta M.N., Mitochondrial DNA deletions in cculopharyngeal muscular dystrophy, FEBS Lett. 418 (1997) 167-170.
-
(1997)
FEBS Lett.
, vol.418
, pp. 167-170
-
-
Lezza, A.M.S.1
Cormio, A.2
Gerardi, P.3
Silvestri, G.4
Servidei, S.5
Serlenga, L.6
Cantatore, P.7
Gadaleta, M.N.8
-
78
-
-
0031940986
-
A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase
-
[78] Melov S., Schneider J.A., Day B.J., Hinerfeld D., Coskun P., Mirra S.S., Crapo J.D., Wallace D.C., A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase, Nature Genet. 18 (1998) 159-163.
-
(1998)
Nature Genet.
, vol.18
, pp. 159-163
-
-
Melov, S.1
Schneider, J.A.2
Day, B.J.3
Hinerfeld, D.4
Coskun, P.5
Mirra, S.S.6
Crapo, J.D.7
Wallace, D.C.8
-
79
-
-
0028220114
-
Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
-
[79] Orr W.C., Sohal R.S., Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster, Science 263 (1994) 1128-1130.
-
(1994)
Science
, vol.263
, pp. 1128-1130
-
-
Orr, W.C.1
Sohal, R.S.2
-
80
-
-
0031864164
-
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
-
[80] Parkes T.L., Elia A.J., Dickinson D., Hilliker A.J., Philippips J.P., Boulianne G.L., Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons, Nature Genet. 19 (1998) 171-174.
-
(1998)
Nature Genet.
, vol.19
, pp. 171-174
-
-
Parkes, T.L.1
Elia, A.J.2
Dickinson, D.3
Hilliker, A.J.4
Philippips, J.P.5
Boulianne, G.L.6
-
81
-
-
0031885843
-
Role of mitochondrial DNA mutations in human aging: Implications for the central nervous system and muscle
-
[81] Brierley E.J., Johnson M.A., Lightowlers R.N., James O.F.W., Turnbull D.M., Role of mitochondrial DNA mutations in human aging: implications for the central nervous system and muscle, Ann. Neurol. 43 (1998) 217-223.
-
(1998)
Ann. Neurol.
, vol.43
, pp. 217-223
-
-
Brierley, E.J.1
Johnson, M.A.2
Lightowlers, R.N.3
James, O.F.W.4
Turnbull, D.M.5
-
82
-
-
0029759443
-
Aging and oxidative stress: Modulation by dietary restriction
-
[82] Yu B.P., Aging and oxidative stress: modulation by dietary restriction, Free Rad. Biol. Med. 21 (1996) 651-668.
-
(1996)
Free Rad. Biol. Med.
, vol.21
, pp. 651-668
-
-
Yu, B.P.1
|