-
1
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky DJ, Emr SD (2000). Autophagy as a regulated pathway of cellular degradation. Science 290(5497): 1717-1721.
-
(2000)
Science
, vol.290
, Issue.5497
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
2
-
-
84892569830
-
An overview of autophagy: Morphology, mechanism, and regulation
-
Parzych KR, Klionsky DJ (2014). An overview of autophagy: morphology, mechanism, and regulation. Antioxid Redox Signal 20(3): 460-473.
-
(2014)
Antioxid Redox Signal
, vol.20
, Issue.3
, pp. 460-473
-
-
Parzych, K.R.1
Klionsky, D.J.2
-
3
-
-
79952355107
-
Selective autophagy mediated by autophagic adapter proteins
-
Johansen T, Lamark T (2011). Selective autophagy mediated by autophagic adapter proteins. Autophagy 7(3): 279-296.
-
(2011)
Autophagy
, vol.7
, Issue.3
, pp. 279-296
-
-
Johansen, T.1
Lamark, T.2
-
4
-
-
84869472835
-
Receptor protein complexes are in control of autophagy
-
Mijaljica D, Nazarko TY, Brumell JH, Huang W-P, Komatsu M, Prescott M, Simonsen A, Yamamoto A, Zhang H, Klionsky DJ, Devenish RJ (2012). Receptor protein complexes are in control of autophagy. Autophagy 8(11): 1701-1705.
-
(2012)
Autophagy
, vol.8
, Issue.11
, pp. 1701-1705
-
-
Mijaljica, D.1
Nazarko, T.Y.2
Brumell, J.H.3
Huang, W.-P.4
Komatsu, M.5
Prescott, M.6
Simonsen, A.7
Yamamoto, A.8
Zhang, H.9
Klionsky, D.J.10
Devenish, R.J.11
-
5
-
-
84901801108
-
Organellophagy: Eliminating cellular building blocks via selective autophagy
-
Okamoto K (2014). Organellophagy: eliminating cellular building blocks via selective autophagy. J Cell Biol 205(4): 435-445.
-
(2014)
J Cell Biol
, vol.205
, Issue.4
, pp. 435-445
-
-
Okamoto, K.1
-
6
-
-
84955242756
-
Ubiquitin-Dependent And Independent Signals In Selective Autophagy
-
Khaminets A, Behl C, Dikic I (2016). Ubiquitin-Dependent And Independent Signals In Selective Autophagy. Trends Cell Biol 26(1): 6-16.
-
(2016)
Trends Cell Biol
, vol.26
, Issue.1
, pp. 6-16
-
-
Khaminets, A.1
Behl, C.2
Dikic, I.3
-
7
-
-
77950510302
-
The Cvt pathway as a model for selective autophagy
-
Lynch-Day MA, Klionsky DJ (2010). The Cvt pathway as a model for selective autophagy. FEBS Lett 584(7): 1359-1366.
-
(2010)
FEBS Lett
, vol.584
, Issue.7
, pp. 1359-1366
-
-
Lynch-Day, M.A.1
Klionsky, D.J.2
-
8
-
-
84946763293
-
Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress
-
Antonucci L, Fagman JB, Kim JY, Todoric J, Gukovsky I, Mackey M, Ellisman MH, Karin M (2015). Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress. Proc Natl Acad Sci U S A 112(45): E6166-6174.
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, Issue.45
, pp. E6166-E6174
-
-
Antonucci, L.1
Fagman, J.B.2
Kim, J.Y.3
Todoric, J.4
Gukovsky, I.5
Mackey, M.6
Ellisman, M.H.7
Karin, M.8
-
9
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R, Yokoyama M, Mishima K, Saito I, Okano H, Mizushima N (2006). Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441(7095): 885-889.
-
(2006)
Nature
, vol.441
, Issue.7095
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
Yokoyama, M.7
Mishima, K.8
Saito, I.9
Okano, H.10
Mizushima, N.11
-
10
-
-
33846702991
-
Autophagy, organelles and ageing
-
Terman A, Gustafsson B, Brunk UT (2007). Autophagy, organelles and ageing. J Pathol 211(2): 134-143.
-
(2007)
J Pathol
, vol.211
, Issue.2
, pp. 134-143
-
-
Terman, A.1
Gustafsson, B.2
Brunk, U.T.3
-
12
-
-
77956416339
-
Autophagy in mammalian development and differentiation
-
Mizushima N, Levine B (2010). Autophagy in mammalian development and differentiation. Nat Cell Biol 12(9): 823-830.
-
(2010)
Nat Cell Biol
, vol.12
, Issue.9
, pp. 823-830
-
-
Mizushima, N.1
Levine, B.2
-
13
-
-
77956472436
-
The role of autophagy during development in higher eukaryotes
-
Di Bartolomeo S, Nazio F, Cecconi F (2010). The role of autophagy during development in higher eukaryotes. Traffic 11(10): 1280-1289.
-
(2010)
Traffic
, vol.11
, Issue.10
, pp. 1280-1289
-
-
Di Bartolomeo, S.1
Nazio, F.2
Cecconi, F.3
-
15
-
-
34247523194
-
Regulation of the oocyte-to-zygote transition
-
Stitzel ML, Seydoux G (2007). Regulation of the oocyte-to-zygote transition. Science 316(5823): 407-408.
-
(2007)
Science
, vol.316
, Issue.5823
, pp. 407-408
-
-
Stitzel, M.L.1
Seydoux, G.2
-
16
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, Yoshimori T, Ohsumi Y, Tokuhisa T, Mizushima N (2004). The role of autophagy during the early neonatal starvation period. Nature 432(7020): 1032-1036.
-
(2004)
Nature
, vol.432
, Issue.7020
, pp. 1032-1036
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
Yamamoto, A.4
Nakaya, H.5
Yoshimori, T.6
Ohsumi, Y.7
Tokuhisa, T.8
Mizushima, N.9
-
17
-
-
76249127368
-
Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo
-
Mortensen M, Ferguson DJ, Edelmann M, Kessler B, Morten KJ, Komatsu M, Simon AK (2010). Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo. Proc Natl Acad Sci U S A 107(2): 832-837.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.2
, pp. 832-837
-
-
Mortensen, M.1
Ferguson, D.J.2
Edelmann, M.3
Kessler, B.4
Morten, K.J.5
Komatsu, M.6
Simon, A.K.7
-
18
-
-
84920514275
-
Autophagy as a pro-death pathway
-
Denton D, Xu T, Kumar S (2015). Autophagy as a pro-death pathway. Immunol Cell Biol 93(1): 35-42.
-
(2015)
Immunol Cell Biol
, vol.93
, Issue.1
, pp. 35-42
-
-
Denton, D.1
Xu, T.2
Kumar, S.3
-
19
-
-
84894565195
-
Self-consumption: The interplay of autophagy and apoptosis
-
Marino G, Niso-Santano M, Baehrecke EH, Kroemer G (2014). Self-consumption: the interplay of autophagy and apoptosis. Nat Rev Mol Cell Biol 15(2): 81-94.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, Issue.2
, pp. 81-94
-
-
Marino, G.1
Niso-Santano, M.2
Baehrecke, E.H.3
Kroemer, G.4
-
20
-
-
70350571244
-
Autophagy, not apoptosis, is essential for midgut cell death in Drosophila
-
Denton D, Shravage B, Simin R, Mills K, Berry DL, Baehrecke EH, Kumar S (2009). Autophagy, not apoptosis, is essential for midgut cell death in Drosophila. Curr Biol 19(20): 1741-1746.
-
(2009)
Curr Biol
, vol.19
, Issue.20
, pp. 1741-1746
-
-
Denton, D.1
Shravage, B.2
Simin, R.3
Mills, K.4
Berry, D.L.5
Baehrecke, E.H.6
Kumar, S.7
-
21
-
-
84937639381
-
Eaten alive: Novel insights into autophagy from multicellular model systems
-
Zhang H, Baehrecke EH (2015). Eaten alive: novel insights into autophagy from multicellular model systems. Trends Cell Biol 25(7): 376-387.
-
(2015)
Trends Cell Biol
, vol.25
, Issue.7
, pp. 376-387
-
-
Zhang, H.1
Baehrecke, E.H.2
-
22
-
-
84255210700
-
Molecular definitions of cell death subroutines: Recommendations of the Nomenclature Committee on Cell Death 2012
-
Galluzzi L, Vitale I, Abrams JM, Alnemri ES, Baehrecke EH, Blagosklonny MV, Dawson TM, Dawson VL, El-Deiry WS, Fulda S, Gottlieb E, Green DR, Hengartner MO, Kepp O, Knight RA, Kumar S, Lipton SA, Lu X, Madeo F, Malorni W, Mehlen P, Nunez G, Peter ME, Piacentini M, Rubinsztein DC, Shi Y, Simon HU, Vandenabeele P, White E, Yuan J, et al. (2012). Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ 19(1): 107-120.
-
(2012)
Cell Death Differ
, vol.19
, Issue.1
, pp. 107-120
-
-
Galluzzi, L.1
Vitale, I.2
Abrams, J.M.3
Alnemri, E.S.4
Baehrecke, E.H.5
Blagosklonny, M.V.6
Dawson, T.M.7
Dawson, V.L.8
El-Deiry, W.S.9
Fulda, S.10
Gottlieb, E.11
Green, D.R.12
Hengartner, M.O.13
Kepp, O.14
Knight, R.A.15
Kumar, S.16
Lipton, S.A.17
Lu, X.18
Madeo, F.19
Malorni, W.20
Mehlen, P.21
Nunez, G.22
Peter, M.E.23
Piacentini, M.24
Rubinsztein, D.C.25
Shi, Y.26
Simon, H.U.27
Vandenabeele, P.28
White, E.29
Yuan, J.30
more..
-
23
-
-
84922541234
-
Autosis and autophagic cell death: The dark side of autophagy
-
Liu Y, Levine B (2015). Autosis and autophagic cell death: the dark side of autophagy. Cell Death Differ 22(3): 367-376.
-
(2015)
Cell Death Differ
, vol.22
, Issue.3
, pp. 367-376
-
-
Liu, Y.1
Levine, B.2
-
24
-
-
84982123825
-
Ferroptosis is an autophagic cell death process
-
Gao M, Monian P, Pan Q, Zhang W, Xiang J, Jiang X (2016). Ferroptosis is an autophagic cell death process. Cell Res.
-
(2016)
Cell Res
-
-
Gao, M.1
Monian, P.2
Pan, Q.3
Zhang, W.4
Xiang, J.5
Jiang, X.6
-
25
-
-
67649607465
-
Autophagy, immunity, and microbial adaptations
-
Deretic V, Levine B (2009). Autophagy, immunity, and microbial adaptations. Cell Host Microbe 5(6): 527-549.
-
(2009)
Cell Host Microbe
, vol.5
, Issue.6
, pp. 527-549
-
-
Deretic, V.1
Levine, B.2
-
26
-
-
84886797274
-
Autophagy in infection, inflammation and immunity
-
Deretic V, Saitoh T, Akira S (2013). Autophagy in infection, inflammation and immunity. Nat Rev Immunol 13(10): 722-737.
-
(2013)
Nat Rev Immunol
, vol.13
, Issue.10
, pp. 722-737
-
-
Deretic, V.1
Saitoh, T.2
Akira, S.3
-
27
-
-
0034683568
-
Tor-mediated induction of autophagy via an Apg1 protein kinase complex
-
Kamada Y, Funakoshi T, Shintani T, Nagano K, Ohsumi M, Ohsumi Y (2000). Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 150(6): 1507-1513.
-
(2000)
J Cell Biol
, vol.150
, Issue.6
, pp. 1507-1513
-
-
Kamada, Y.1
Funakoshi, T.2
Shintani, T.3
Nagano, K.4
Ohsumi, M.5
Ohsumi, Y.6
-
28
-
-
33846514235
-
Hierarchy of Atg proteins in pre-autophagosomal structure organization
-
Suzuki K, Kubota Y, Sekito T, Ohsumi Y (2007). Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells 12(2): 209-218.
-
(2007)
Genes Cells
, vol.12
, Issue.2
, pp. 209-218
-
-
Suzuki, K.1
Kubota, Y.2
Sekito, T.3
Ohsumi, Y.4
-
29
-
-
84893742616
-
Early steps in autophagy depend on direct phosphorylation of Atg9 by the Atg1 kinase
-
Papinski D, Schuschnig M, Reiter W, Wilhelm L, Barnes CA, Maiolica A, Hansmann I, Pfaffenwimmer T, Kijanska M, Stoffel I, Lee SS, Brezovich A, Lou JH, Turk BE, Aebersold R, Ammerer G, Peter M, Kraft C (2014). Early steps in autophagy depend on direct phosphorylation of Atg9 by the Atg1 kinase. Mol Cell 53(3): 471-483.
-
(2014)
Mol Cell
, vol.53
, Issue.3
, pp. 471-483
-
-
Papinski, D.1
Schuschnig, M.2
Reiter, W.3
Wilhelm, L.4
Barnes, C.A.5
Maiolica, A.6
Hansmann, I.7
Pfaffenwimmer, T.8
Kijanska, M.9
Stoffel, I.10
Lee, S.S.11
Brezovich, A.12
Lou, J.H.13
Turk, B.E.14
Aebersold, R.15
Ammerer, G.16
Peter, M.17
Kraft, C.18
-
30
-
-
0027905021
-
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting
-
Schu PV, Takegawa K, Fry MJ, Stack JH, Waterfield MD, Emr SD (1993). Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science 260(5104): 88-91.
-
(1993)
Science
, vol.260
, Issue.5104
, pp. 88-91
-
-
Schu, P.V.1
Takegawa, K.2
Fry, M.J.3
Stack, J.H.4
Waterfield, M.D.5
Emr, S.D.6
-
31
-
-
0035809160
-
Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
-
Kihara A, Noda T, Ishihara N, Ohsumi Y (2001). Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol 152(3): 519-530.
-
(2001)
J Cell Biol
, vol.152
, Issue.3
, pp. 519-530
-
-
Kihara, A.1
Noda, T.2
Ishihara, N.3
Ohsumi, Y.4
-
32
-
-
77950506156
-
Regulation of autophagy by phosphatidylinositol 3-phosphate
-
Burman C, Ktistakis NT (2010). Regulation of autophagy by phosphatidylinositol 3-phosphate. FEBS Lett 584(7): 1302-1312.
-
(2010)
FEBS Lett
, vol.584
, Issue.7
, pp. 1302-1312
-
-
Burman, C.1
Ktistakis, N.T.2
-
33
-
-
53049102656
-
The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function
-
Obara K, Sekito T, Niimi K, Ohsumi Y (2008). The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function. J Biol Chem 283(35): 23972-23980.
-
(2008)
J Biol Chem
, vol.283
, Issue.35
, pp. 23972-23980
-
-
Obara, K.1
Sekito, T.2
Niimi, K.3
Ohsumi, Y.4
-
34
-
-
0028230738
-
Ultrastructural analysis of the autophagic process in yeast: Detection of autophagosomes and their characterization
-
Baba M, Takeshige K, Baba N, Ohsumi Y (1994). Ultrastructural analysis of the autophagic process in yeast: detection of autophagosomes and their characterization. J Cell Biol 124(6): 903-913.
-
(1994)
J Cell Biol
, vol.124
, Issue.6
, pp. 903-913
-
-
Baba, M.1
Takeshige, K.2
Baba, N.3
Ohsumi, Y.4
-
35
-
-
0035286734
-
Molecular dissection of autophagy: Two ubiquitin-like systems
-
Ohsumi Y (2001). Molecular dissection of autophagy: two ubiquitin-like systems. Nat Rev Mol Cell Biol 2(3): 211-216.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, Issue.3
, pp. 211-216
-
-
Ohsumi, Y.1
-
36
-
-
50249154070
-
In vivo reconstitution of autophagy in Saccharomyces cerevisiae
-
Cao Y, Cheong H, Song H, Klionsky DJ (2008). In vivo reconstitution of autophagy in Saccharomyces cerevisiae. J Cell Biol 182(4): 703-713.
-
(2008)
J Cell Biol
, vol.182
, Issue.4
, pp. 703-713
-
-
Cao, Y.1
Cheong, H.2
Song, H.3
Klionsky, D.J.4
-
37
-
-
84864282281
-
Autophagosome formation can be achieved in the absence of Atg18 by expressing engineered PAS-targeted Atg2
-
Kobayashi T, Suzuki K, Ohsumi Y (2012). Autophagosome formation can be achieved in the absence of Atg18 by expressing engineered PAS-targeted Atg2. FEBS Lett 586(16): 2473-2478.
-
(2012)
FEBS Lett
, vol.586
, Issue.16
, pp. 2473-2478
-
-
Kobayashi, T.1
Suzuki, K.2
Ohsumi, Y.3
-
38
-
-
0034614934
-
Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways
-
Noda T, Kim J, Huang W-P, Baba M, Tokunaga C, Ohsumi Y, Klionsky DJ (2000). Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways. J Cell Biol 148(3): 465-480.
-
(2000)
J Cell Biol
, vol.148
, Issue.3
, pp. 465-480
-
-
Noda, T.1
Kim, J.2
Huang, W.-P.3
Baba, M.4
Tokunaga, C.5
Ohsumi, Y.6
Klionsky, D.J.7
-
39
-
-
84864991509
-
Atg9 vesicles are an important membrane source during early steps of autophagosome formation
-
Yamamoto H, Kakuta S, Watanabe TM, Kitamura A, Sekito T, Kondo-Kakuta C, Ichikawa R, Kinjo M, Ohsumi Y (2012). Atg9 vesicles are an important membrane source during early steps of autophagosome formation. J Cell Biol 198(2): 219-233.
-
(2012)
J Cell Biol
, vol.198
, Issue.2
, pp. 219-233
-
-
Yamamoto, H.1
Kakuta, S.2
Watanabe, T.M.3
Kitamura, A.4
Sekito, T.5
Kondo-Kakuta, C.6
Ichikawa, R.7
Kinjo, M.8
Ohsumi, Y.9
-
40
-
-
27644544004
-
Atg9 cycles between mitochondria and the pre-autophagosomal structure in yeasts
-
Reggiori F, Shintani T, Nair U, Klionsky DJ (2005). Atg9 cycles between mitochondria and the pre-autophagosomal structure in yeasts. Autophagy 1(2): 101-109.
-
(2005)
Autophagy
, vol.1
, Issue.2
, pp. 101-109
-
-
Reggiori, F.1
Shintani, T.2
Nair, U.3
Klionsky, D.J.4
-
41
-
-
0034676037
-
The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway
-
Kirisako T, Ichimura Y, Okada H, Kabeya Y, Mizushima N, Yoshimori T, Ohsumi M, Takao T, Noda T, Ohsumi Y (2000). The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 151(2): 263-276.
-
(2000)
J Cell Biol
, vol.151
, Issue.2
, pp. 263-276
-
-
Kirisako, T.1
Ichimura, Y.2
Okada, H.3
Kabeya, Y.4
Mizushima, N.5
Yoshimori, T.6
Ohsumi, M.7
Takao, T.8
Noda, T.9
Ohsumi, Y.10
-
42
-
-
84862618804
-
A role for Atg8-PE deconjugation in autophagosome biogenesis
-
Nair U, Yen W-L, Mari M, Cao Y, Xie Z, Baba M, Reggiori F, Klionsky DJ (2012). A role for Atg8-PE deconjugation in autophagosome biogenesis. Autophagy 8(5): 780-793.
-
(2012)
Autophagy
, vol.8
, Issue.5
, pp. 780-793
-
-
Nair, U.1
Yen, W.-L.2
Mari, M.3
Cao, Y.4
Xie, Z.5
Baba, M.6
Reggiori, F.7
Klionsky, D.J.8
-
43
-
-
84901381389
-
The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17
-
Jiang P, Nishimura T, Sakamaki Y, Itakura E, Hatta T, Natsume T, Mizushima N (2014). The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17. Mol Biol Cell 25(8): 1327-1337.
-
(2014)
Mol Biol Cell
, vol.25
, Issue.8
, pp. 1327-1337
-
-
Jiang, P.1
Nishimura, T.2
Sakamaki, Y.3
Itakura, E.4
Hatta, T.5
Natsume, T.6
Mizushima, N.7
-
44
-
-
0034809331
-
Aut5/Cvt17p, a putative lipase essential for disintegration of autophagic bodies inside the vacuole
-
Epple UD, Suriapranata I, Eskelinen E-L, Thumm M (2001). Aut5/Cvt17p, a putative lipase essential for disintegration of autophagic bodies inside the vacuole. J Bacteriol 183(20): 5942-5955.
-
(2001)
J Bacteriol
, vol.183
, Issue.20
, pp. 5942-5955
-
-
Epple, U.D.1
Suriapranata, I.2
Eskelinen, E.-L.3
Thumm, M.4
-
45
-
-
0035910577
-
Degradation of lipid vesicles in the yeast vacuole requires function of Cvt17, a putative lipase
-
Teter SA, Eggerton KP, Scott SV, Kim J, Fischer AM, Klionsky DJ (2001). Degradation of lipid vesicles in the yeast vacuole requires function of Cvt17, a putative lipase. J Biol Chem 276(3): 2083-2087.
-
(2001)
J Biol Chem
, vol.276
, Issue.3
, pp. 2083-2087
-
-
Teter, S.A.1
Eggerton, K.P.2
Scott, S.V.3
Kim, J.4
Fischer, A.M.5
Klionsky, D.J.6
-
46
-
-
33845407202
-
Atg22 recycles amino acids to link the degradative and recycling functions of autophagy
-
Yang Z, Huang J, Geng J, Nair U, Klionsky DJ (2006). Atg22 recycles amino acids to link the degradative and recycling functions of autophagy. Mol Biol Cell 17(12): 5094-5104.
-
(2006)
Mol Biol Cell
, vol.17
, Issue.12
, pp. 5094-5104
-
-
Yang, Z.1
Huang, J.2
Geng, J.3
Nair, U.4
Klionsky, D.J.5
-
47
-
-
0014083718
-
Influence of glucagon, an inducer of cellular autophagy, on some physical properties of rat liver lysosomes
-
Deter RL, de Duve C (1967). Influence of glucagon, an inducer of cellular autophagy, on some physical properties of rat liver lysosomes. J Cell Biol 33(2): 437-449.
-
(1967)
J Cell Biol
, vol.33
, Issue.2
, pp. 437-449
-
-
Deter, R.L.1
de Duve, C.2
-
48
-
-
0017697151
-
Induction of autophagy by amino-acid deprivation in perfused rat liver
-
Mortimore GE, Schworer CM (1977). Induction of autophagy by amino-acid deprivation in perfused rat liver. Nature 270(5633): 174-176.
-
(1977)
Nature
, vol.270
, Issue.5633
, pp. 174-176
-
-
Mortimore, G.E.1
Schworer, C.M.2
-
49
-
-
84859778293
-
MTOR signaling in growth control and disease
-
Laplante M, Sabatini DM (2012). mTOR signaling in growth control and disease. Cell 149(2): 274-293.
-
(2012)
Cell
, vol.149
, Issue.2
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
50
-
-
75749090429
-
Tor directly controls the Atg1 kinase complex to regulate autophagy
-
Kamada Y, Yoshino K, Kondo C, Kawamata T, Oshiro N, Yonezawa K, Ohsumi Y (2010). Tor directly controls the Atg1 kinase complex to regulate autophagy. Mol Cell Biol 30(4): 1049-1058.
-
(2010)
Mol Cell Biol
, vol.30
, Issue.4
, pp. 1049-1058
-
-
Kamada, Y.1
Yoshino, K.2
Kondo, C.3
Kawamata, T.4
Oshiro, N.5
Yonezawa, K.6
Ohsumi, Y.7
-
51
-
-
84890848742
-
Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy
-
Yuan HX, Russell RC, Guan K-L (2013). Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy. Autophagy 9(12): 1983-1995.
-
(2013)
Autophagy
, vol.9
, Issue.12
, pp. 1983-1995
-
-
Yuan, H.X.1
Russell, R.C.2
Guan, K.-L.3
-
52
-
-
77951768486
-
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
-
Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM (2010). Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell 141(2): 290-303.
-
(2010)
Cell
, vol.141
, Issue.2
, pp. 290-303
-
-
Sancak, Y.1
Bar-Peled, L.2
Zoncu, R.3
Markhard, A.L.4
Nada, S.5
Sabatini, D.M.6
-
53
-
-
84866431363
-
Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1
-
Bar-Peled L, Schweitzer LD, Zoncu R, Sabatini DM (2012). Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1. Cell 150(6): 1196-1208.
-
(2012)
Cell
, vol.150
, Issue.6
, pp. 1196-1208
-
-
Bar-Peled, L.1
Schweitzer, L.D.2
Zoncu, R.3
Sabatini, D.M.4
-
54
-
-
84940550513
-
Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A
-
Wong PM, Feng Y, Wang J, Shi R, Jiang X (2015). Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A. Nat Commun 6:8048.
-
(2015)
Nat Commun
, vol.6
, pp. 8048
-
-
Wong, P.M.1
Feng, Y.2
Wang, J.3
Shi, R.4
Jiang, X.5
-
55
-
-
84885455062
-
The eIF2alpha/ATF4 pathway is essential for stress-induced autophagy gene expression
-
B'Chir W, Maurin AC, Carraro V, Averous J, Jousse C, Muranishi Y, Parry L, Stepien G, Fafournoux P, Bruhat A (2013). The eIF2alpha/ATF4 pathway is essential for stress-induced autophagy gene expression. Nucleic Acids Res 41(16): 7683-7699.
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.16
, pp. 7683-7699
-
-
B'chir, W.1
Maurin, A.C.2
Carraro, V.3
Averous, J.4
Jousse, C.5
Muranishi, Y.6
Parry, L.7
Stepien, G.8
Fafournoux, P.9
Bruhat, A.10
-
56
-
-
80955177196
-
TFEB links autophagy to lysosomal biogenesis
-
Settembre C, Di Malta C, Polito VA, Garcia Arencibia M, Vetrini F, Erdin S, Erdin SU, Huynh T, Medina D, Colella P, Sardiello M, Rubinsztein DC, Ballabio A (2011). TFEB links autophagy to lysosomal biogenesis. Science 332(6036): 1429-1433.
-
(2011)
Science
, vol.332
, Issue.6036
, pp. 1429-1433
-
-
Settembre, C.1
Di Malta, C.2
Polito, V.A.3
Garcia Arencibia, M.4
Vetrini, F.5
Erdin, S.6
Erdin, S.U.7
Huynh, T.8
Medina, D.9
Colella, P.10
Sardiello, M.11
Rubinsztein, D.C.12
Ballabio, A.13
-
57
-
-
70350128436
-
The Tor and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagy
-
Stephan JS, Yeh YY, Ramachandran V, Deminoff SJ, Herman PK (2009). The Tor and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagy. Proc Natl Acad Sci U S A 106(40): 17049-17054.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.40
, pp. 17049-17054
-
-
Stephan, J.S.1
Yeh, Y.Y.2
Ramachandran, V.3
Deminoff, S.J.4
Herman, P.K.5
-
58
-
-
84858782079
-
AMPK: A nutrient and energy sensor that maintains energy homeostasis
-
Hardie DG, Ross FA, Hawley SA (2012). AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol 13(4): 251-262.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, Issue.4
, pp. 251-262
-
-
Hardie, D.G.1
Ross, F.A.2
Hawley, S.A.3
-
59
-
-
84891745585
-
Autophagy regulation by nutrient signaling
-
Russell RC, Yuan HX, Guan KL (2014). Autophagy regulation by nutrient signaling. Cell Res 24(1): 42-57.
-
(2014)
Cell Res
, vol.24
, Issue.1
, pp. 42-57
-
-
Russell, R.C.1
Yuan, H.X.2
Guan, K.L.3
-
60
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim J, Kundu M, Viollet B, Guan KL (2011). AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 13(2): 132-141.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.2
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
61
-
-
84929502727
-
How to control self-digestion: Transcriptional, post-transcriptional, and post-translational regulation of autophagy
-
Feng Y, Yao Z, Klionsky DJ (2015). How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy. Trends Cell Biol 25(6): 354-363.
-
(2015)
Trends Cell Biol
, vol.25
, Issue.6
, pp. 354-363
-
-
Feng, Y.1
Yao, Z.2
Klionsky, D.J.3
-
62
-
-
84901346313
-
Autophagy--a key player in cellular and body metabolism
-
Kim KH, Lee MS (2014). Autophagy--a key player in cellular and body metabolism. Nat Rev Endocrinol 10(6): 322-337.
-
(2014)
Nat Rev Endocrinol
, vol.10
, Issue.6
, pp. 322-337
-
-
Kim, K.H.1
Lee, M.S.2
-
63
-
-
84870943446
-
The Ume6-Sin3-Rpd3 complex regulates ATG8 transcription to control autophagosome size
-
Backues SK, Lynch-Day MA, Klionsky DJ (2012). The Ume6-Sin3-Rpd3 complex regulates ATG8 transcription to control autophagosome size. Autophagy 8(12): 1835-1836.
-
(2012)
Autophagy
, vol.8
, Issue.12
, pp. 1835-1836
-
-
Backues, S.K.1
Lynch-Day, M.A.2
Klionsky, D.J.3
-
64
-
-
84902652820
-
Transcriptional regulation by Pho23 modulates the frequency of autophagosome formation
-
Jin M, He D, Backues SK, Freeberg MA, Liu X, Kim JK, Klionsky DJ (2014). Transcriptional regulation by Pho23 modulates the frequency of autophagosome formation. Curr Biol 24(12): 1314-1322.
-
(2014)
Curr Biol
, vol.24
, Issue.12
, pp. 1314-1322
-
-
Jin, M.1
He, D.2
Backues, S.K.3
Freeberg, M.A.4
Liu, X.5
Kim, J.K.6
Klionsky, D.J.7
-
65
-
-
84891738225
-
Autophagy and human diseases
-
Jiang P, Mizushima N (2014). Autophagy and human diseases. Cell Res 24(1): 69-79.
-
(2014)
Cell Res
, vol.24
, Issue.1
, pp. 69-79
-
-
Jiang, P.1
Mizushima, N.2
-
66
-
-
34548265278
-
Autophagy and human disease
-
Huang J, Klionsky DJ (2007). Autophagy and human disease. Cell Cycle 6(15): 1837-1849.
-
(2007)
Cell Cycle
, vol.6
, Issue.15
, pp. 1837-1849
-
-
Huang, J.1
Klionsky, D.J.2
-
67
-
-
11444267601
-
Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases
-
Nixon RA (2005). Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases. Neurobiol Aging 26(3): 373-382.
-
(2005)
Neurobiol Aging
, vol.26
, Issue.3
, pp. 373-382
-
-
Nixon, R.A.1
-
68
-
-
33744916798
-
Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1
-
Shibata M, Lu T, Furuya T, Degterev A, Mizushima N, Yoshimori T, MacDonald M, Yankner B, Yuan J (2006). Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1. J Biol Chem 281(20): 14474-14485.
-
(2006)
J Biol Chem
, vol.281
, Issue.20
, pp. 14474-14485
-
-
Shibata, M.1
Lu, T.2
Furuya, T.3
Degterev, A.4
Mizushima, N.5
Yoshimori, T.6
Macdonald, M.7
Yankner, B.8
Yuan, J.9
-
69
-
-
33748414185
-
Autophagy and neurodegeneration
-
Komatsu M, Kominami E, Tanaka K (2006). Autophagy and neurodegeneration. Autophagy 2(4): 315-317.
-
(2006)
Autophagy
, vol.2
, Issue.4
, pp. 315-317
-
-
Komatsu, M.1
Kominami, E.2
Tanaka, K.3
-
70
-
-
79953854897
-
Alzheimer's disease: The challenge of the second century
-
Holtzman DM, Morris JC, Goate AM (2011). Alzheimer's disease: the challenge of the second century. Sci Transl Med 3(77): 77-71.
-
(2011)
Sci Transl Med
, vol.3
, Issue.77
, pp. 77
-
-
Holtzman, D.M.1
Morris, J.C.2
Goate, A.M.3
-
71
-
-
14844303381
-
Extensive involvement of autophagy in Alzheimer disease: An immuno-electron microscopy study
-
Nixon RA, Wegiel J, Kumar A, Yu WH, Peterhoff C, Cataldo A, Cuervo AM (2005). Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study. J Neuropathol Exp Neurol 64(2): 113-122.
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, Issue.2
, pp. 113-122
-
-
Nixon, R.A.1
Wegiel, J.2
Kumar, A.3
Yu, W.H.4
Peterhoff, C.5
Cataldo, A.6
Cuervo, A.M.7
-
72
-
-
26444587508
-
Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease
-
Yu WH, Cuervo AM, Kumar A, Peterhoff CM, Schmidt SD, Lee JH, Mohan PS, Mercken M, Farmery MR, Tjernberg LO, Jiang Y, Duff K, Uchiyama Y, Naslund J, Mathews PM, Cataldo AM, Nixon RA (2005). Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease. J Cell Biol 171(1): 87-98.
-
(2005)
J Cell Biol
, vol.171
, Issue.1
, pp. 87-98
-
-
Yu, W.H.1
Cuervo, A.M.2
Kumar, A.3
Peterhoff, C.M.4
Schmidt, S.D.5
Lee, J.H.6
Mohan, P.S.7
Mercken, M.8
Farmery, M.R.9
Tjernberg, L.O.10
Jiang, Y.11
Duff, K.12
Uchiyama, Y.13
Naslund, J.14
Mathews, P.M.15
Cataldo, A.M.16
Nixon, R.A.17
|