Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A

Nature Communications

Volumn 6, Issue , 2015, Pages

  Wong, Pui Mun ^a   Feng, Yan ^a   Wang, Junru ^a   Shi, Rong ^a,b   Jiang, Xuejun ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Central South University   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GREEN FLUORESCENT PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2A; RAPAMYCIN; ULK1 PROTEIN; UNCLASSIFIED DRUG; AMINO ACID; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; PHOSPHOPROTEIN PHOSPHATASE 2; PPP2R2A PROTEIN, HUMAN; PPP2R2A PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE; SERINE THREONINE PROTEIN KINASE ULK1; SIGNAL PEPTIDE; TARGET OF RAPAMYCIN KINASE; ULK1 PROTEIN, HUMAN; ULK1 PROTEIN, MOUSE;

AMINO ACID; CATABOLISM; CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; HOMEOSTASIS; INHIBITION; MAMMAL; PROTEIN; STARVATION;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER GROWTH; CELL GROWTH; CELL SURVIVAL; CELL VIABILITY; COMPLEX FORMATION; CRYSTAL STRUCTURE; DEPHOSPHORYLATION; ENZYME ACTIVE SITE; FIBROBLAST; FLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; IN VITRO STUDY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; GENE SILENCING; GENETICS; HUMAN; METABOLISM; PANCREAS CARCINOMA; PANCREAS TUMOR; PHOSPHORYLATION; STARVATION; TUMOR CELL LINE;

MAMMALIA;

AMINO ACIDS; ANIMALS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEIN-1 HOMOLOG; CARCINOMA, PANCREATIC DUCTAL; CELL LINE, TUMOR; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICROSCOPY, FLUORESCENCE; MULTIPROTEIN COMPLEXES; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PROTEIN PHOSPHATASE 2; PROTEIN-SERINE-THREONINE KINASES; STARVATION; TOR SERINE-THREONINE KINASES;

EID: 84940550513     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9048     Document Type: Article

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