Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation

Cell Reports

Volumn 19, Issue 10, 2017, Pages 2074-2087

  Arensdorf, Angela M ^a   Dillard, Miriam E ^a   Menke, Jacob M ^a,b   Frank, Matthew W ^a   Rock, Charles O ^a   Ogden, Stacey K ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b RHODES COLLEGE   (United States)

Author keywords

arachidonic acid; phospholipase A2; primary cilium; signal transduction; Smoothened; Sonic Hedgehog

Indexed keywords

ARACHIDONIC ACID; CYCLOPAMINE; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; PHOSPHOLIPASE A2; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI; UNCLASSIFIED DRUG; PHOSPHOLIPASE A2 GROUP IV; SHH PROTEIN, MOUSE; SMO PROTEIN, MOUSE;

ALLOSTERISM; ARACHIDONIC ACID METABOLISM; ARTICLE; CILIARY MOTILITY; CONTROLLED STUDY; CYSTEINE RICH DOMAIN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN DOMAIN; SEVEN TRANSMEMBRANE; SIGNAL TRANSDUCTION; ANIMAL; CILIUM; ENZYME ACTIVATION; GENETICS; METABOLISM; MOUSE; NIH 3T3 CELL LINE; PROTEIN TRANSPORT;

ANIMALS; CILIA; ENZYME ACTIVATION; GROUP IV PHOSPHOLIPASES A2; HEDGEHOG PROTEINS; MICE; NIH 3T3 CELLS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SMOOTHENED RECEPTOR;

EID: 85020282210     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.05.033     Document Type: Article

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