Protective effect of Chlorogenic acid against methotrexate induced oxidative stress, inflammation and apoptosis in rat liver: An experimental approach

Chemico-Biological Interactions

Volumn 272, Issue , 2017, Pages 80-91

  Ali, Nemat ^a   Rashid, Summya ^a   Nafees, Sana ^a   Hasan, Syed Kazim ^a   Shahid, Ayaz ^a   Majed, Ferial ^a   Sultana, Sarwat ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Antioxidants; Apoptosis; Hepatotoxicity; MTX; ROS

Indexed keywords

CASPASE 3; CASPASE 9; CATALASE; CHLOROGENIC ACID; CYCLOOXYGENASE 2; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; INDUCIBLE NITRIC OXIDE SYNTHASE; METHOTREXATE; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; ANTIOXIDANT; PROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HISTOPATHOLOGY; INFLAMMATION; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; UPREGULATION; ANIMAL; DRUG EFFECTS; LIPID PEROXIDATION; LIVER; METABOLISM; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CHLOROGENIC ACID; DOWN-REGULATION; GLUTATHIONE; INFLAMMATION; LIPID PEROXIDATION; LIVER; MALE; METHOTREXATE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR;

EID: 85019448174     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2017.05.002     Document Type: Article

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