Beneficial effects of Chrysin against Methotrexate-induced hepatotoxicity via attenuation of oxidative stress and apoptosis

Molecular and Cellular Biochemistry

Volumn 385, Issue 1-2, 2014, Pages 215-223

  Ali, Nemat ^a   Rashid, Summya ^a   Nafees, Sana ^a   Hasan, Syed Kazim ^a   Sultana, Sarwat ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Apoptosis; Chrysin; Hepatotoxicity; Methotrexate; Oxidative stress

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CATALASE; CHRYSIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; LACTATE DEHYDROGENASE; MALONALDEHYDE; METHOTREXATE; PROTEIN BAX; PROTEIN P53; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIVER; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; THERAPY EFFECT; TOXIC HEPATITIS;

RATTUS;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BIOLOGICAL MARKERS; CASPASE 3; DRUG-INDUCED LIVER INJURY; FLAVONOIDS; GLUTATHIONE; IMMUNOHISTOCHEMISTRY; LIVER; MALE; MALONDIALDEHYDE; METHOTREXATE; OXIDATIVE STRESS; RATS; RATS, WISTAR; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84890547554     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1830-4     Document Type: Article

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