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Volumn 66, Issue 6, 2017, Pages 1138-1153

Non-Alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases

Author keywords

Cardiovascular Disease; Diabetes Mellitus; Nonalcoholic Steatohepatitis

Indexed keywords

C REACTIVE PROTEIN; GLUCOSE; HEMOGLOBIN A1C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; JUNCTIONAL ADHESION MOLECULE A; LOW DENSITY LIPOPROTEIN; MYELOID DIFFERENTIATION FACTOR 88; TRIMETHYLAMINE; TRIMETHYLAMINE OXIDE; TUMOR NECROSIS FACTOR; ADIPOCYTOKINE; CYTOKINE;

EID: 85019439188     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2017-313884     Document Type: Article
Times cited : (835)

References (199)
  • 1
    • 84927796763 scopus 로고    scopus 로고
    • Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: Implications for prognosis and clinical management
    • McPherson S, Hardy T, Henderson E, et al. Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: Implications for prognosis and clinical management. J Hepatol 2015;62:1148-55.
    • (2015) J Hepatol , vol.62 , pp. 1148-1155
    • McPherson, S.1    Hardy, T.2    Henderson, E.3
  • 2
    • 84924938800 scopus 로고    scopus 로고
    • Fibrosis progression in nonalcoholic fatty liver vs nonalcoholic steatohepatitis: A systematic review and meta-Analysis of paired-biopsy studies
    • Singh S, Allen AM, Wang Z, et al. Fibrosis progression in nonalcoholic fatty liver vs nonalcoholic steatohepatitis: A systematic review and meta-Analysis of paired-biopsy studies. Clin Gastroenterol Hepatol 2015;13:643-54.e9.
    • (2015) Clin Gastroenterol Hepatol , vol.13 , pp. 643-643e9
    • Singh, S.1    Allen, A.M.2    Wang, Z.3
  • 3
    • 84878930738 scopus 로고    scopus 로고
    • Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis
    • Anstee QM, Targher G, Day CP. Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis. Nat Rev Gastroenterol Hepatol 2013;10:330-44.
    • (2013) Nat Rev Gastroenterol Hepatol , vol.10 , pp. 330-344
    • Anstee, Q.M.1    Targher, G.2    Day, C.P.3
  • 4
    • 84928209634 scopus 로고    scopus 로고
    • Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up
    • Ekstedt M, Hagström H, Nasr P, et al. Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up. Hepatology 2015;61:1547-54.
    • (2015) Hepatology , vol.61 , pp. 1547-1554
    • Ekstedt, M.1    Hagström, H.2    Nasr, P.3
  • 5
    • 84938057875 scopus 로고    scopus 로고
    • Liver fibrosis, but no other histologic features, is associated with long-Term outcomes of patients with nonalcoholic fatty liver disease
    • Angulo P, Kleiner DE, Dam-Larsen S, et al. Liver fibrosis, but no other histologic features, is associated with long-Term outcomes of patients with nonalcoholic fatty liver disease. Gastroenterology 2015;149:389-97.e10.
    • (2015) Gastroenterology , vol.149 , pp. 389-97e10
    • Angulo, P.1    Kleiner, D.E.2    Dam-Larsen, S.3
  • 6
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002;346:1221-31.
    • (2002) N Engl J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 7
    • 0037382786 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome
    • Marchesini G, Bugianesi E, Forlani G, et al. Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology 2003;37:917-23.
    • (2003) Hepatology , vol.37 , pp. 917-923
    • Marchesini, G.1    Bugianesi, E.2    Forlani, G.3
  • 8
    • 77952529040 scopus 로고    scopus 로고
    • A position statement on NAFLD/NASH based on the EASL
    • Ratziu V, Bellentani S, Cortez-Pinto H, et al. A position statement on NAFLD/NASH based on the EASL 2009 special conference. J Hepatol 2010;53:372-84.
    • (2010) J Hepatol 2009 , vol.53 , pp. 372-384
    • Ratziu, V.1    Bellentani, S.2    Cortez-Pinto, H.3
  • 10
    • 64549089599 scopus 로고    scopus 로고
    • Association of serum uric acid level with non-Alcoholic fatty liver disease: A cross-sectional study
    • Li Y, Xu C, Yu C, et al. Association of serum uric acid level with non-Alcoholic fatty liver disease: A cross-sectional study. J Hepatol 2009;50:1029-34.
    • (2009) J Hepatol , vol.50 , pp. 1029-1034
    • Li, Y.1    Xu, C.2    Yu, C.3
  • 11
    • 84874109849 scopus 로고    scopus 로고
    • Elevated serum uric acid levels are associated with non-Alcoholic fatty liver disease independently of metabolic syndrome features in the United States: Liver ultrasound data from the National Health and Nutrition Examination Survey
    • Sirota JC, McFann K, Targher G, et al. Elevated serum uric acid levels are associated with non-Alcoholic fatty liver disease independently of metabolic syndrome features in the United States: liver ultrasound data from the National Health and Nutrition Examination Survey. Metab Clin Exp 2013;62:392-9.
    • (2013) Metab Clin Exp , vol.62 , pp. 392-399
    • Sirota, J.C.1    McFann, K.2    Targher, G.3
  • 12
    • 80052501527 scopus 로고    scopus 로고
    • Hyperuricemia is associated with histological liver damage in patients with non-Alcoholic fatty liver disease
    • Petta S, Cammà C, Cabibi D, et al. Hyperuricemia is associated with histological liver damage in patients with non-Alcoholic fatty liver disease. Aliment Pharmacol Ther 2011;34:757-66.
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 757-766
    • Petta, S.1    Cammà, C.2    Cabibi, D.3
  • 13
    • 3042744737 scopus 로고    scopus 로고
    • Beyond insulin resistance in NASH: TNF-Alpha or adiponectin?
    • Hui JM, Hodge A, Farrell GC, et al. Beyond insulin resistance in NASH: TNF-Alpha or adiponectin? Hepatology 2004;40:46-54.
    • (2004) Hepatology , vol.40 , pp. 46-54
    • Hui, J.M.1    Hodge, A.2    Farrell, G.C.3
  • 14
    • 33646853899 scopus 로고    scopus 로고
    • Associations between plasma adiponectin concentrations and liver histology in patients with nonalcoholic fatty liver disease
    • Targher G, Bertolini L, Rodella S, et al. Associations between plasma adiponectin concentrations and liver histology in patients with nonalcoholic fatty liver disease. Clin Endocrinol (Oxf ) 2006;64:679-83.
    • (2006) Clin Endocrinol (Oxf , vol.64 , pp. 679-683
    • Targher, G.1    Bertolini, L.2    Rodella, S.3
  • 15
    • 21244445862 scopus 로고    scopus 로고
    • Plasma adiponectin in nonalcoholic fatty liver is related to hepatic insulin resistance and hepatic fat content, not to liver disease severity
    • Bugianesi E, Pagotto U, Manini R, et al. Plasma adiponectin in nonalcoholic fatty liver is related to hepatic insulin resistance and hepatic fat content, not to liver disease severity. J Clin Endocrinol Metab 2005;90:3498-504.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 3498-3504
    • Bugianesi, E.1    Pagotto, U.2    Manini, R.3
  • 16
    • 34547485376 scopus 로고    scopus 로고
    • Associations between serum 25-hydroxyvitamin D3 concentrations and liver histology in patients with non-Alcoholic fatty liver disease
    • Targher G, Bertolini L, Scala L, et al. Associations between serum 25-hydroxyvitamin D3 concentrations and liver histology in patients with non-Alcoholic fatty liver disease. Nutr Metab Cardiovasc Dis 2007;17:517-24.
    • (2007) Nutr Metab Cardiovasc Dis , vol.17 , pp. 517-524
    • Targher, G.1    Bertolini, L.2    Scala, L.3
  • 17
    • 79954662342 scopus 로고    scopus 로고
    • Risk of chronic kidney disease in patients with non-Alcoholic fatty liver disease
    • Targher G, Chonchol M, Zoppini G, et al. Risk of chronic kidney disease in patients with non-Alcoholic fatty liver disease: is there a link? J Hepatol 2011;54:1020-9.
    • (2011) Is There A Link? J Hepatol , vol.54 , pp. 1020-1029
    • Targher, G.1    Chonchol, M.2    Zoppini, G.3
  • 18
    • 67649170396 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease as a contributor to hypercoagulation and thrombophilia in the metabolic syndrome
    • Targher G, Chonchol M, Miele L, et al. Nonalcoholic fatty liver disease as a contributor to hypercoagulation and thrombophilia in the metabolic syndrome. Semin Thromb Hemost 2009;35:277-87.
    • (2009) Semin Thromb Hemost , vol.35 , pp. 277-287
    • Targher, G.1    Chonchol, M.2    Miele, L.3
  • 19
    • 77950017450 scopus 로고    scopus 로고
    • Circulating levels and hepatic expression of molecular mediators of atherosclerosis in nonalcoholic fatty liver disease
    • Sookoian S, Castaño GO, Burgueño AL, et al. Circulating levels and hepatic expression of molecular mediators of atherosclerosis in nonalcoholic fatty liver disease. Atherosclerosis 2010;209:585-91.
    • (2010) Atherosclerosis , vol.209 , pp. 585-591
    • Sookoian, S.1    Castaño, G.O.2    Burgueño, A.L.3
  • 20
    • 44949233003 scopus 로고    scopus 로고
    • Increased hepatic and circulating interleukin-6 levels in human nonalcoholic steatohepatitis
    • Wieckowska A, Papouchado BG, Li Z, et al. Increased hepatic and circulating interleukin-6 levels in human nonalcoholic steatohepatitis. Am J Gastroenterol 2008;103:1372-9.
    • (2008) Am J Gastroenterol , vol.103 , pp. 1372-1379
    • Wieckowska, A.1    Papouchado, B.G.2    Li, Z.3
  • 21
    • 80053219898 scopus 로고    scopus 로고
    • Liver transcriptional profile of atherosclerosis-related genes in human nonalcoholic fatty liver disease
    • Sookoian S, Gianotti TF, Rosselli MS, et al. Liver transcriptional profile of atherosclerosis-related genes in human nonalcoholic fatty liver disease. Atherosclerosis 2011;218:378-85.
    • (2011) Atherosclerosis , vol.218 , pp. 378-385
    • Sookoian, S.1    Gianotti, T.F.2    Rosselli, M.S.3
  • 22
    • 84961291855 scopus 로고    scopus 로고
    • Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis
    • Weston CJ, Shepherd EL, Claridge LC, et al. Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis. J Clin Invest 2015;125:501-20.
    • (2015) J Clin Invest , vol.125 , pp. 501-520
    • Weston, C.J.1    Shepherd, E.L.2    Claridge, L.C.3
  • 23
    • 84941907029 scopus 로고    scopus 로고
    • Systemic complications of nonalcoholic fatty liver disease: When the liver is not an innocent bystander
    • Vanni E, Marengo A, Mezzabotta L, et al. Systemic complications of nonalcoholic fatty liver disease: when the liver is not an innocent bystander. Semin Liver Dis 2015;35:236-49.
    • (2015) Semin Liver Dis , vol.35 , pp. 236-249
    • Vanni, E.1    Marengo, A.2    Mezzabotta, L.3
  • 24
    • 4644305245 scopus 로고    scopus 로고
    • Relation of nonalcoholic hepatic steatosis to early carotid atherosclerosis in healthy men: Role of visceral fat accumulation
    • Targher G, Bertolini L, Padovani R, et al. Relation of nonalcoholic hepatic steatosis to early carotid atherosclerosis in healthy men: role of visceral fat accumulation. Diabetes Care 2004;27:2498-500.
    • (2004) Diabetes Care , vol.27 , pp. 2498-2500
    • Targher, G.1    Bertolini, L.2    Padovani, R.3
  • 25
    • 18244367137 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is associated with carotid atherosclerosis: A case-control study
    • Brea A, Mosquera D, Martín E, et al. Nonalcoholic fatty liver disease is associated with carotid atherosclerosis: A case-control study. Arterioscler Thromb Vasc Biol 2005;25:1045-50.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1045-1050
    • Brea, A.1    Mosquera, D.2    Martín, E.3
  • 26
    • 17144387889 scopus 로고    scopus 로고
    • Hepatic steatosis is associated with an increased risk of carotid atherosclerosis
    • Volzke H, Robinson DM, Kleine V, et al. Hepatic steatosis is associated with an increased risk of carotid atherosclerosis. World J Gastroenterol 2005;11:1848-53.
    • (2005) World J Gastroenterol , vol.11 , pp. 1848-1853
    • Volzke, H.1    Robinson, D.M.2    Kleine, V.3
  • 27
    • 37649012018 scopus 로고    scopus 로고
    • Carotid artery intima-media thickness in nonalcoholic fatty liver disease
    • Fracanzani AL, Burdick L, Raselli S, et al. Carotid artery intima-media thickness in nonalcoholic fatty liver disease. Am J Med 2008;121:72-8.
    • (2008) Am J Med , vol.121 , pp. 72-78
    • Fracanzani, A.L.1    Burdick, L.2    Raselli, S.3
  • 28
    • 84859954406 scopus 로고    scopus 로고
    • Fatty liver index, gamma-glutamyltransferase, and early carotid plaques
    • Kozakova M, Palombo C, Eng MP, et al. Fatty liver index, gamma-glutamyltransferase, and early carotid plaques. Hepatology 2012;55:1406-15.
    • (2012) Hepatology , vol.55 , pp. 1406-1415
    • Kozakova, M.1    Palombo, C.2    Eng, M.P.3
  • 29
    • 77954951936 scopus 로고    scopus 로고
    • Increased arterial stiffness in nonalcoholic fatty liver disease: The Cardio-GOOSE study
    • Salvi P, Ruffini R, Agnoletti D, et al. Increased arterial stiffness in nonalcoholic fatty liver disease: The Cardio-GOOSE study. J Hypertens 2010;28:1699-707.
    • (2010) J Hypertens , vol.28 , pp. 1699-1707
    • Salvi, P.1    Ruffini, R.2    Agnoletti, D.3
  • 30
    • 84856708597 scopus 로고    scopus 로고
    • The relationship between arterial stiffness and nonalcoholic fatty liver disease
    • Lee YJ, Shim JY, Moon BS, et al. The relationship between arterial stiffness and nonalcoholic fatty liver disease. Dig Dis Sci 2012;57:196-203.
    • (2012) Dig Dis Sci , vol.57 , pp. 196-203
    • Lee, Y.J.1    Shim, J.Y.2    Moon, B.S.3
  • 31
    • 23044512117 scopus 로고    scopus 로고
    • Endothelial dysfunction and cardiovascular risk profile in nonalcoholic fatty liver disease
    • Villanova N, Moscatiello S, Ramilli S, et al. Endothelial dysfunction and cardiovascular risk profile in nonalcoholic fatty liver disease. Hepatology 2005;42:473-80.
    • (2005) Hepatology , vol.42 , pp. 473-480
    • Villanova, N.1    Moscatiello, S.2    Ramilli, S.3
  • 32
    • 78049523237 scopus 로고    scopus 로고
    • Functional and morphological vascular changes in pediatric nonalcoholic fatty liver disease
    • Pacifico L, Anania C, Martino F, et al. Functional and morphological vascular changes in pediatric nonalcoholic fatty liver disease. Hepatology 2010;52:1643-51.
    • (2010) Hepatology , vol.52 , pp. 1643-1651
    • Pacifico, L.1    Anania, C.2    Martino, F.3
  • 33
    • 50849096389 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease is strongly associated with carotid atherosclerosis: A systematic review
    • Sookoian S, Pirola CJ. Non-Alcoholic fatty liver disease is strongly associated with carotid atherosclerosis: A systematic review. J Hepatol 2008;49:600-7.
    • (2008) J Hepatol , vol.49 , pp. 600-607
    • Sookoian, S.1    Pirola, C.J.2
  • 34
    • 84884508163 scopus 로고    scopus 로고
    • A systematic review: Burden and severity of subclinical cardiovascular disease among those with nonalcoholic fatty liver should we care?
    • Oni ET, Agatston AS, Blaha MJ, et al. A systematic review: burden and severity of subclinical cardiovascular disease among those with nonalcoholic fatty liver; should we care? Atherosclerosis 2013;230:258-67.
    • (2013) Atherosclerosis , vol.230 , pp. 258-267
    • Oni, E.T.1    Agatston, A.S.2    Blaha, M.J.3
  • 35
    • 84868141067 scopus 로고    scopus 로고
    • Fatty liver, insulin resistance, and features of metabolic syndrome: Relationships with coronary artery calcium in 10, 153 people
    • Sung KC, Wild SH, Kwag HJ, et al. Fatty liver, insulin resistance, and features of metabolic syndrome: relationships with coronary artery calcium in 10, 153 people. Diabetes Care 2012;35:2359-64.
    • (2012) Diabetes Care , vol.35 , pp. 2359-2364
    • Sung, K.C.1    Wild, S.H.2    Kwag, H.J.3
  • 36
    • 33750630075 scopus 로고    scopus 로고
    • Cardiac abnormalities as a new manifestation of nonalcoholic fatty liver disease: Echocardiographic and tissue Doppler imaging assessment
    • Goland S, Shimoni S, Zornitzki T, et al. Cardiac abnormalities as a new manifestation of nonalcoholic fatty liver disease: echocardiographic and tissue Doppler imaging assessment. J Clin Gastroenterol 2006;40:949-55.
    • (2006) J Clin Gastroenterol , vol.40 , pp. 949-955
    • Goland, S.1    Shimoni, S.2    Zornitzki, T.3
  • 37
    • 70349482410 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease is associated with left ventricular diastolic dysfunction in essential hypertension
    • Fallo F, Dalla Pozza A, Sonino N, et al. Non-Alcoholic fatty liver disease is associated with left ventricular diastolic dysfunction in essential hypertension. Nutr Metab Cardiovasc Dis 2009;19:646-53.
    • (2009) Nutr Metab Cardiovasc Dis , vol.19 , pp. 646-653
    • Fallo, F.1    Dalla Pozza, A.2    Sonino, N.3
  • 38
    • 84859048319 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is associated with left ventricular diastolic dysfunction in patients with type 2 diabetes
    • Bonapace S, Perseghin G, Molon G, et al. Nonalcoholic fatty liver disease is associated with left ventricular diastolic dysfunction in patients with type 2 diabetes. Diabetes Care 2012;35:389-95.
    • (2012) Diabetes Care , vol.35 , pp. 389-395
    • Bonapace, S.1    Perseghin, G.2    Molon, G.3
  • 39
    • 84878630492 scopus 로고    scopus 로고
    • Cardiac structure and function are altered in adults with non-Alcoholic fatty liver disease
    • Hallsworth K, Hollingsworth KG, Thoma C, et al. Cardiac structure and function are altered in adults with non-Alcoholic fatty liver disease. J Hepatol 2013;58:757-62.
    • (2013) J Hepatol , vol.58 , pp. 757-762
    • Hallsworth, K.1    Hollingsworth, K.G.2    Thoma, C.3
  • 40
    • 38649091680 scopus 로고    scopus 로고
    • Increased mediastinal fat and impaired left ventricular energy metabolism in young men with newly found fatty liver
    • Perseghin G, Lattuada G, De Cobelli F, et al. Increased mediastinal fat and impaired left ventricular energy metabolism in young men with newly found fatty liver. Hepatology 2008;47:51-8.
    • (2008) Hepatology , vol.47 , pp. 51-58
    • Perseghin, G.1    Lattuada, G.2    De Cobelli, F.3
  • 41
    • 77955060310 scopus 로고    scopus 로고
    • Effects of hepatic triglyceride content on myocardial metabolism in type 2 diabetes
    • Rijzewijk LJ, Jonker JT, van der Meer RW, et al. Effects of hepatic triglyceride content on myocardial metabolism in type 2 diabetes. J Am Coll Cardiol 2010;56:225-33.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 225-233
    • Rijzewijk, L.J.1    Jonker, J.T.2    Van Der Meer, R.W.3
  • 42
    • 33745856570 scopus 로고    scopus 로고
    • Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in patients with type 2 diabetes
    • Lautamäki R, Borra R, Iozzo P, et al. Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in patients with type 2 diabetes. Am J Physiol Endocrinol Metab 2006;291:E282-90.
    • (2006) Am J Physiol Endocrinol Metab , vol.291 , pp. E282-E290
    • Lautamäki, R.1    Borra, R.2    Iozzo, P.3
  • 43
    • 84861329163 scopus 로고    scopus 로고
    • Independent association between nonalcoholic fatty liver disease and cardiovascular disease in the US population
    • Stepanova M, Younossi ZM. Independent association between nonalcoholic fatty liver disease and cardiovascular disease in the US population. Clin Gastroenterol Hepatol 2012;10:646-50.
    • (2012) Clin Gastroenterol Hepatol , vol.10 , pp. 646-650
    • Stepanova, M.1    Younossi, Z.M.2
  • 44
    • 83755178774 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease and mortality among US adults: Prospective cohort study
    • Lazo M, Hernaez R, Bonekamp S, et al. Non-Alcoholic fatty liver disease and mortality among US adults: prospective cohort study. BMJ 2011;343:d6891.
    • (2011) BMJ , vol.343 , pp. d6891
    • Lazo, M.1    Hernaez, R.2    Bonekamp, S.3
  • 45
    • 34247605492 scopus 로고    scopus 로고
    • Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients
    • Targher G, Bertolini L, Padovani R, et al. Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients. Diabetes Care 2007;30:1212-18.
    • (2007) Diabetes Care , vol.30 , pp. 1212-1218
    • Targher, G.1    Bertolini, L.2    Padovani, R.3
  • 47
    • 77449127455 scopus 로고    scopus 로고
    • Presence of coronary plaques in patients with nonalcoholic fatty liver disease
    • Assy N, Djibre A, Farah R, et al. Presence of coronary plaques in patients with nonalcoholic fatty liver disease. Radiology 2010;254:393-400.
    • (2010) Radiology , vol.254 , pp. 393-400
    • Assy, N.1    Djibre, A.2    Farah, R.3
  • 48
    • 84951941164 scopus 로고    scopus 로고
    • Long-Term clinical outcomes after fatty liver screening in patients undergoing coronary angiogram: A prospective cohort study
    • Wong VW, Wong GL, Yeung JC, et al. Long-Term clinical outcomes after fatty liver screening in patients undergoing coronary angiogram: A prospective cohort study. Hepatology 2016;63:754-63.
    • (2016) Hepatology , vol.63 , pp. 754-763
    • Wong, V.W.1    Wong, G.L.2    Yeung, J.C.3
  • 49
    • 84987950377 scopus 로고    scopus 로고
    • Association of non-Alcoholic fatty liver disease with major adverse cardiovascular events: A systematic review and meta-Analysis
    • Wu S, Wu F, Ding Y, et al. Association of non-Alcoholic fatty liver disease with major adverse cardiovascular events: A systematic review and meta-Analysis. Sci Rep 2016;6:33386.
    • (2016) Sci Rep , vol.6 , pp. 33386
    • Wu, S.1    Wu, F.2    Ding, Y.3
  • 50
    • 33750606061 scopus 로고    scopus 로고
    • Long-Term follow-up of patients with NAFLD and elevated liver enzymes
    • Ekstedt M, Franzén LE, Mathiesen UL, et al. Long-Term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology 2006;44:865-73.
    • (2006) Hepatology , vol.44 , pp. 865-873
    • Ekstedt, M.1    Franzén, L.E.2    Mathiesen, U.L.3
  • 51
    • 75449088414 scopus 로고    scopus 로고
    • Decreased survival of subjects with elevated liver function tests during a 28-year follow-up
    • Söderberg C, Stal P, Askling J, et al. Decreased survival of subjects with elevated liver function tests during a 28-year follow-up. Hepatology 2010;51:595-602.
    • (2010) Hepatology , vol.51 , pp. 595-602
    • Söderberg, C.1    Stal, P.2    Askling, J.3
  • 52
    • 80555136061 scopus 로고    scopus 로고
    • Meta-Analysis: Natural history of non-Alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity
    • Musso G, Gambino R, Cassader M, et al. Meta-Analysis: natural history of non-Alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity. Ann Med 2011;43:617-49.
    • (2011) Ann Med , vol.43 , pp. 617-649
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 53
    • 84995489897 scopus 로고    scopus 로고
    • Persistent nonalcoholic fatty liver disease increases risk for carotid atherosclerosis
    • Sinn DH, Cho SJ, Gu S, et al. Persistent nonalcoholic fatty liver disease increases risk for carotid atherosclerosis. Gastroenterology 2016;151:481-8.e1.
    • (2016) Gastroenterology , vol.151 , pp. 481-481e1
    • Sinn, D.H.1    Cho, S.J.2    Gu, S.3
  • 54
    • 84986570776 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease and progression of coronary artery calcium score: A retrospective cohort study
    • Sinn DH, Kang D, Chang Y, et al. Non-Alcoholic fatty liver disease and progression of coronary artery calcium score: A retrospective cohort study. Gut 2017;66:323-9.
    • Gut , vol.2017 , Issue.66 , pp. 323-329
    • Sinn, D.H.1    Kang, D.2    Chang, Y.3
  • 55
    • 84964575197 scopus 로고    scopus 로고
    • Fatty liver is an independent predictor of early carotid atherosclerosis
    • Pais R, Giral P, Khan JF, et al. Fatty liver is an independent predictor of early carotid atherosclerosis. J Hepatol 2016;65:95-102.
    • (2016) J Hepatol , vol.65 , pp. 95-102
    • Pais, R.1    Giral, P.2    Khan, J.F.3
  • 56
    • 85009953681 scopus 로고    scopus 로고
    • Bi-directional analysis between fatty liver and cardiovascular disease risk factors
    • Ma J, Hwang SJ, Pedley A, et al. Bi-directional analysis between fatty liver and cardiovascular disease risk factors. J Hepatol 2017;66:390-7.
    • J Hepatol , vol.2017 , Issue.66 , pp. 390-397
    • Ma, J.1    Hwang, S.J.2    Pedley, A.3
  • 57
    • 84876130551 scopus 로고    scopus 로고
    • Association between noninvasive fibrosis markers and mortality among adults with nonalcoholic fatty liver disease in the United States
    • Kim D, Kim WR, Kim HJ, et al. Association between noninvasive fibrosis markers and mortality among adults with nonalcoholic fatty liver disease in the United States. Hepatology 2013;57:1357-65.
    • (2013) Hepatology , vol.57 , pp. 1357-1365
    • Kim, D.1    Kim, W.R.2    Kim, H.J.3
  • 58
    • 72949097025 scopus 로고    scopus 로고
    • Ultrasonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels
    • Haring R, Wallaschofski H, Nauck M, et al. Ultrasonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels. Hepatology 2009;50:1403-11.
    • (2009) Hepatology , vol.50 , pp. 1403-1411
    • Haring, R.1    Wallaschofski, H.2    Nauck, M.3
  • 59
    • 34247647418 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is a novel predictor of cardiovascular disease
    • Hamaguchi M, Kojima T, Takeda N, et al. Nonalcoholic fatty liver disease is a novel predictor of cardiovascular disease. World J Gastroenterol 2007;13:1579-84.
    • (2007) World J Gastroenterol , vol.13 , pp. 1579-1584
    • Hamaguchi, M.1    Kojima, T.2    Takeda, N.3
  • 60
    • 84897534860 scopus 로고    scopus 로고
    • Fatty liver predicts the risk for cardiovascular events in middle-Aged population: A population-based cohort study
    • Pisto P, Santaniemi M, Bloigu R, et al. Fatty liver predicts the risk for cardiovascular events in middle-Aged population: A population-based cohort study. BMJ Open 2014;4:e004973.
    • (2014) BMJ Open , vol.4 , pp. e004973
    • Pisto, P.1    Santaniemi, M.2    Bloigu, R.3
  • 61
    • 0033038672 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity
    • Matteoni CA, Younossi ZM, Gramlich T, et al. Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity. Gastroenterology 1999;116: 1413-19.
    • (1999) Gastroenterology , vol.116 , pp. 1413-1419
    • Matteoni, C.A.1    Younossi, Z.M.2    Gramlich, T.3
  • 62
    • 2342419920 scopus 로고    scopus 로고
    • Long term prognosis of fatty liver: Risk of chronic liver disease and death
    • Dam-Larsen S, Franzmann M, Andersen IB, et al. Long term prognosis of fatty liver: risk of chronic liver disease and death. Gut 2004;53:750-5.
    • (2004) Gut , vol.53 , pp. 750-755
    • Dam-Larsen, S.1    Franzmann, M.2    Andersen, I.B.3
  • 63
    • 58849134985 scopus 로고    scopus 로고
    • Long-Term follow-up of patients with nonalcoholic fatty liver
    • Rafiq N, Bai C, Fang Y, et al. Long-Term follow-up of patients with nonalcoholic fatty liver. Clin Gastroenterol Hepatol 2009;7:234-8.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 234-238
    • Rafiq, N.1    Bai, C.2    Fang, Y.3
  • 64
    • 22344452893 scopus 로고    scopus 로고
    • The natural history of nonalcoholic fatty liver disease: A population-based cohort study
    • Adams LA, Lymp JF, St Sauver J, et al. The natural history of nonalcoholic fatty liver disease: A population-based cohort study. Gastroenterology 2005;129:113-21.
    • (2005) Gastroenterology , vol.129 , pp. 113-121
    • Adams, L.A.1    Lymp, J.F.2    St Sauver, J.3
  • 65
    • 0344099055 scopus 로고    scopus 로고
    • Prognosis of patients with liver cirrhosis and spontaneous bacterial peritonitis
    • Jepsen P, Vilstrup H, Møller JK, et al. Prognosis of patients with liver cirrhosis and spontaneous bacterial peritonitis. Hepatogastroenterology 2003;50:2133-6.
    • (2003) Hepatogastroenterology , vol.50 , pp. 2133-2136
    • Jepsen, P.1    Vilstrup, H.2    Møller, J.K.3
  • 66
    • 34547673500 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is independently associated with an increased incidence of cardiovascular events in type 2 diabetic patients
    • Targher G, Bertolini L, Rodella S, et al. Nonalcoholic fatty liver disease is independently associated with an increased incidence of cardiovascular events in type 2 diabetic patients. Diabetes Care 2007;30:2119-21.
    • (2007) Diabetes Care , vol.30 , pp. 2119-2121
    • Targher, G.1    Bertolini, L.2    Rodella, S.3
  • 67
    • 84863148823 scopus 로고    scopus 로고
    • Natural course of nonalcoholic fatty liver disease in southern China: A prospective cohort study
    • Zhou YJ, Li YY, Nie YQ, et al. Natural course of nonalcoholic fatty liver disease in southern China: A prospective cohort study. J Dig Dis 2012;13:153-60.
    • (2012) J Dig Dis , vol.13 , pp. 153-160
    • Zhou, Y.J.1    Li, Y.Y.2    Nie, Y.Q.3
  • 68
    • 84991083809 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease and risk of incident cardiovascular disease: A meta-Analysis
    • Targher G, Byrne CD, Lonardo A, et al. Non-Alcoholic fatty liver disease and risk of incident cardiovascular disease: A meta-Analysis. J Hepatol 2016;65:589-600.
    • (2016) J Hepatol , vol.65 , pp. 589-600
    • Targher, G.1    Byrne, C.D.2    Lonardo, A.3
  • 69
    • 84941885943 scopus 로고    scopus 로고
    • The genetics of nonalcoholic fatty liver disease: Spotlight on PNPLA3 and TM6SF2
    • Anstee QM, Day CP. The genetics of nonalcoholic fatty liver disease: spotlight on PNPLA3 and TM6SF2. Semin Liver Dis 2015;35:270-90.
    • (2015) Semin Liver Dis , vol.35 , pp. 270-290
    • Anstee, Q.M.1    Day, C.P.2
  • 70
    • 56749096610 scopus 로고    scopus 로고
    • Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
    • Romeo S, Kozlitina J, Xing C, et al. Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet 2008;40:1461-5.
    • (2008) Nat Genet , vol.40 , pp. 1461-1465
    • Romeo, S.1    Kozlitina, J.2    Xing, C.3
  • 71
    • 77950607738 scopus 로고    scopus 로고
    • Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease
    • Valenti L, Al-Serri A, Daly AK, et al. Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. Hepatology 2010;51:1209-17.
    • (2010) Hepatology , vol.51 , pp. 1209-1217
    • Valenti, L.1    Al-Serri, A.2    Daly, A.K.3
  • 72
    • 84902688337 scopus 로고    scopus 로고
    • Carriage of the PNPLA3 rs738409 CG polymorphism confers an increased risk of non-Alcoholic fatty liver disease associated hepatocellular carcinoma
    • Liu YL, Patman GL, Leathart JB, et al. Carriage of the PNPLA3 rs738409 CG polymorphism confers an increased risk of non-Alcoholic fatty liver disease associated hepatocellular carcinoma. J Hepatol 2014;61:75-81.
    • (2014) J Hepatol , vol.61 , pp. 75-81
    • Liu, Y.L.1    Patman, G.L.2    Leathart, J.B.3
  • 74
    • 84898058711 scopus 로고    scopus 로고
    • Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease
    • Kozlitina J, Smagris E, Stender S, et al. Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease. Nat Genet 2014;46:352-6.
    • (2014) Nat Genet , vol.46 , pp. 352-356
    • Kozlitina, J.1    Smagris, E.2    Stender, S.3
  • 75
    • 84903708160 scopus 로고    scopus 로고
    • TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-Alcoholic fatty liver disease
    • Liu YL, Reeves HL, Burt AD, et al. TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-Alcoholic fatty liver disease. Nat Commun 2014;5:4309.
    • (2014) Nat Commun , vol.5 , pp. 4309
    • Liu, Y.L.1    Reeves, H.L.2    Burt, A.D.3
  • 76
    • 84921487729 scopus 로고    scopus 로고
    • Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease
    • Dongiovanni P, Petta S, Maglio C, et al. Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease. Hepatology 2015;61:506-14.
    • (2015) Hepatology , vol.61 , pp. 506-514
    • Dongiovanni, P.1    Petta, S.2    Maglio, C.3
  • 77
    • 84898058547 scopus 로고    scopus 로고
    • Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk
    • Holmen OL, Zhang H, Fan Y, et al. Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk. Nat Genet 2014;46:345-51.
    • (2014) Nat Genet , vol.46 , pp. 345-351
    • Holmen, O.L.1    Zhang, H.2    Fan, Y.3
  • 78
    • 84925357379 scopus 로고    scopus 로고
    • TM6SF2: Catch-22 in the fight against nonalcoholic fatty liver disease and cardiovascular disease?
    • Kahali B, Liu YL, Daly AK, et al. TM6SF2: catch-22 in the fight against nonalcoholic fatty liver disease and cardiovascular disease? Gastroenterology 2015;148:679-84.
    • (2015) Gastroenterology , vol.148 , pp. 679-684
    • Kahali, B.1    Liu, Y.L.2    Daly, A.K.3
  • 79
    • 84868646303 scopus 로고    scopus 로고
    • Multigenerational epigenetic adaptation of the hepatic wound-healing response
    • Zeybel M, Hardy T, Wong YK, et al. Multigenerational epigenetic adaptation of the hepatic wound-healing response. Nat Med 2012;18:1369-77.
    • (2012) Nat Med , vol.18 , pp. 1369-1377
    • Zeybel, M.1    Hardy, T.2    Wong, Y.K.3
  • 80
    • 84969179560 scopus 로고    scopus 로고
    • Differential DNA methylation of genes involved in fibrosis progression in non-Alcoholic fatty liver disease and alcoholic liver disease
    • Zeybel M, Hardy T, Robinson SM, et al. Differential DNA methylation of genes involved in fibrosis progression in non-Alcoholic fatty liver disease and alcoholic liver disease. Clin Epigenetics 2015;7:25.
    • (2015) Clin Epigenetics , vol.7 , pp. 25
    • Zeybel, M.1    Hardy, T.2    Robinson, S.M.3
  • 81
    • 84962873354 scopus 로고    scopus 로고
    • Plasma DNA methylation: A potential biomarker for stratification of liver fibrosis in non-Alcoholic fatty liver disease
    • [Epub ahead of print 21 Mar 2016]
    • Hardy T, Zeybel M, Day CP, et al. Plasma DNA methylation: A potential biomarker for stratification of liver fibrosis in non-Alcoholic fatty liver disease. Gut 2016. doi: 10.1136/gutjnl-2016-311526. [Epub ahead of print 21 Mar 2016].
    • (2016) Gut
    • Hardy, T.1    Zeybel, M.2    Day, C.P.3
  • 82
    • 85030032769 scopus 로고    scopus 로고
    • The integration of epigenetics and genetics in nutrition research for CVD risk factors
    • Ma Y, Ordovas JM. The integration of epigenetics and genetics in nutrition research for CVD risk factors. Proc Nutr Soc 2016:1-14.
    • (2016) Proc Nutr Soc , pp. 1-14
    • Ma, Y.1    Ordovas, J.M.2
  • 83
    • 84956671651 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease as a predictor of atrial fibrillation in middle-Aged population (OPERA study
    • Käräjämäki AJ, Pätsi OP, Savolainen M, et al. Non-Alcoholic fatty liver disease as a predictor of atrial fibrillation in middle-Aged population (OPERA study). PLoS One 2015;10:e0142937.
    • (2015) PLoS One , vol.10 , pp. e0142937
    • Käräjämäki, A.J.1    Pätsi, O.P.2    Savolainen, M.3
  • 84
    • 84874317741 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease is associated with an increased incidence of atrial fibrillation in patients with type 2 diabetes
    • Targher G, Valbusa F, Bonapace S, et al. Non-Alcoholic fatty liver disease is associated with an increased incidence of atrial fibrillation in patients with type 2 diabetes. PLoS One 2013;8:e57183.
    • (2013) PLoS One , vol.8 , pp. e57183
    • Targher, G.1    Valbusa, F.2    Bonapace, S.3
  • 85
    • 84942874843 scopus 로고    scopus 로고
    • Heart valve calcification in patients with type 2 diabetes and nonalcoholic fatty liver disease
    • Mantovani A, Pernigo M, Bergamini C, et al. Heart valve calcification in patients with type 2 diabetes and nonalcoholic fatty liver disease. Metab Clin Exp 2015;64:879-87.
    • (2015) Metab Clin Exp , vol.64 , pp. 879-887
    • Mantovani, A.1    Pernigo, M.2    Bergamini, C.3
  • 86
    • 85019456799 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is associated with QT prolongation in the general population
    • Hung CS, Tseng PH, Tu CH, et al. Nonalcoholic fatty liver disease is associated with QT prolongation in the general population. J Am Heart Assoc 2015;4: e001820.
    • (2015) J Am Heart Assoc , vol.4 , pp. e001820
    • Hung, C.S.1    Tseng, P.H.2    Tu, C.H.3
  • 87
    • 84980334568 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is associated with ventricular arrhythmias in patients with type 2 diabetes referred for clinically indicated 24-hour Holter monitoring
    • Mantovani A, Rigamonti A, Bonapace S, et al. Nonalcoholic fatty liver disease is associated with ventricular arrhythmias in patients with type 2 diabetes referred for clinically indicated 24-hour Holter monitoring. Diabetes Care 2016;39:1416-23.
    • (2016) Diabetes Care , vol.39 , pp. 1416-1423
    • Mantovani, A.1    Rigamonti, A.2    Bonapace, S.3
  • 88
    • 84861992004 scopus 로고    scopus 로고
    • The Framingham risk score and heart disease in nonalcoholic fatty liver disease
    • Treeprasertsuk S, Leverage S, Adams LA, et al. The Framingham risk score and heart disease in nonalcoholic fatty liver disease. Liver Int 2012;32:945-50.
    • (2012) Liver Int , vol.32 , pp. 945-950
    • Treeprasertsuk, S.1    Leverage, S.2    Adams, L.A.3
  • 89
    • 39049102073 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and proliferative/laser-Treated retinopathy in type 2 diabetic patients
    • Targher G, Bertolini L, Rodella S, et al. Non-Alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and proliferative/laser-Treated retinopathy in type 2 diabetic patients. Diabetologia 2008;51:444-50.
    • (2008) Diabetologia , vol.51 , pp. 444-450
    • Targher, G.1    Bertolini, L.2    Rodella, S.3
  • 90
    • 77955665639 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and retinopathy in type 1 diabetic patients
    • Targher G, Bertolini L, Chonchol M, et al. Non-Alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and retinopathy in type 1 diabetic patients. Diabetologia 2010;53:1341-8.
    • (2010) Diabetologia , vol.53 , pp. 1341-1348
    • Targher, G.1    Bertolini, L.2    Chonchol, M.3
  • 91
    • 84863023329 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease associated with impairment of kidney function in nondiabetes population
    • Li G, Shi W, Hug H, et al. Nonalcoholic fatty liver disease associated with impairment of kidney function in nondiabetes population. Biochem Med (Zagreb) 2012;22:92-9.
    • (2012) Biochem Med (Zagreb , vol.22 , pp. 92-99
    • Li, G.1    Shi, W.2    Hug, H.3
  • 92
    • 84868250561 scopus 로고    scopus 로고
    • Association between nonalcoholic liver disease and chronic kidney disease: An ultrasound analysis from NHANES 1988-1994
    • Sirota JC, McFann K, Targher G, et al. Association between nonalcoholic liver disease and chronic kidney disease: An ultrasound analysis from NHANES 1988-1994. Am J Nephrol 2012;36:466-71.
    • (2012) Am J Nephrol , vol.36 , pp. 466-471
    • Sirota, J.C.1    McFann, K.2    Targher, G.3
  • 93
    • 84881536928 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease and chronic kidney disease in Koreans aged 50 years or older
    • Ahn AL, Choi JK, Kim MN, et al. Non-Alcoholic fatty liver disease and chronic kidney disease in Koreans aged 50 years or older. Korean J Fam Med 2013;34:199-205.
    • (2013) Korean J Fam Med , vol.34 , pp. 199-205
    • Ahn, A.L.1    Choi, J.K.2    Kim, M.N.3
  • 94
    • 84890401791 scopus 로고    scopus 로고
    • Chronic kidney disease and nonalcoholic Fatty liver disease proven by transient elastography
    • Mikolasevic I, Racki S, Bubic I, et al. Chronic kidney disease and nonalcoholic Fatty liver disease proven by transient elastography. Kidney Blood Press Res 2013;37:305-10.
    • (2013) Kidney Blood Press Res , vol.37 , pp. 305-310
    • Mikolasevic, I.1    Racki, S.2    Bubic, I.3
  • 95
    • 84958764638 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease is a risk factor for the development of diabetic nephropathy in patients with type 2 diabetes mellitus
    • Jia G, Di F, Wang Q, et al. Non-Alcoholic fatty liver disease is a risk factor for the development of diabetic nephropathy in patients with type 2 diabetes mellitus. PLoS One 2015;10:e0142808.
    • (2015) PLoS One , vol.10 , pp. e0142808
    • Jia, G.1    Di Wang F, Q.2
  • 96
    • 84939570182 scopus 로고    scopus 로고
    • Intrahepatic triglyceride content is independently associated with chronic kidney disease in obese adults: A cross-sectional study
    • Pan LL, Zhang HJ, Huang ZF, et al. Intrahepatic triglyceride content is independently associated with chronic kidney disease in obese adults: A cross-sectional study. Metab Clin Exp 2015;64:1077-85.
    • (2015) Metab Clin Exp , vol.64 , pp. 1077-1085
    • Pan, L.L.1    Zhang, H.J.2    Huang, Z.F.3
  • 97
    • 84959474592 scopus 로고    scopus 로고
    • High FIB-4 index as an independent risk factor of prevalent chronic kidney disease in patients with nonalcoholic fatty liver disease
    • Xu HW, Hsu YC, Chang CH, et al. High FIB-4 index as an independent risk factor of prevalent chronic kidney disease in patients with nonalcoholic fatty liver disease. Hepatol Int 2016;10:340-6.
    • (2016) Hepatol Int , vol.10 , pp. 340-346
    • Xu, H.W.1    Hsu, Y.C.2    Chang, C.H.3
  • 98
    • 84979885346 scopus 로고    scopus 로고
    • The impact of nonalcoholic fatty liver disease on renal function in children with overweight/obesity
    • Pacifico L, Bonci E, Andreoli GM, et al. The impact of nonalcoholic fatty liver disease on renal function in children with overweight/obesity. Int J Mol Sci 2016;17.
    • (2016) Int J Mol Sci , vol.17
    • Pacifico, L.1    Bonci, E.2    Andreoli, G.M.3
  • 99
    • 78650323871 scopus 로고    scopus 로고
    • Relationship between kidney function and liver histology in subjects with nonalcoholic steatohepatitis
    • Targher G, Bertolini L, Rodella S, et al. Relationship between kidney function and liver histology in subjects with nonalcoholic steatohepatitis. Clin J Am Soc Nephrol 2010;5:2166-71.
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 2166-2171
    • Targher, G.1    Bertolini, L.2    Rodella, S.3
  • 100
    • 77956625813 scopus 로고    scopus 로고
    • Microalbuminuria in nondiabetic patients with nonalcoholic fatty liver disease: Association with liver fibrosis
    • Yilmaz Y, Alahdab YO, Yonal O, et al. Microalbuminuria in nondiabetic patients with nonalcoholic fatty liver disease: Association with liver fibrosis. Metab Clin Exp 2010;59:1327-30.
    • (2010) Metab Clin Exp , vol.59 , pp. 1327-1330
    • Yilmaz, Y.1    Alahdab, Y.O.2    Yonal, O.3
  • 101
    • 79955026956 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis and increased risk of chronic kidney disease
    • Yasui K, Sumida Y, Mori Y, et al. Nonalcoholic steatohepatitis and increased risk of chronic kidney disease. Metab Clin Exp 2011;60:735-9.
    • (2011) Metab Clin Exp , vol.60 , pp. 735-739
    • Yasui, K.1    Sumida, Y.2    Mori, Y.3
  • 102
    • 83455201868 scopus 로고    scopus 로고
    • Implications of worse renal dysfunction and medical comorbidities in patients with NASH undergoing liver transplant evaluation: Impact on MELD and more
    • Park CW, Tsai NT, Wong LL. Implications of worse renal dysfunction and medical comorbidities in patients with NASH undergoing liver transplant evaluation: impact on MELD and more. Clin Transplant 2011;25:E606-11.
    • (2011) Clin Transplant , vol.25 , pp. E606-E611
    • Park, C.W.1    Tsai, N.T.2    Wong, L.L.3
  • 103
    • 84855547156 scopus 로고    scopus 로고
    • Impaired renal function in morbid obese patients with nonalcoholic fatty liver disease
    • Machado MV, Gonçalves S, Carepa F, et al. Impaired renal function in morbid obese patients with nonalcoholic fatty liver disease. Liver Int 2012;32:241-8.
    • (2012) Liver Int , vol.32 , pp. 241-248
    • Machado, M.V.1    Gonçalves, S.2    Carepa, F.3
  • 104
    • 85014129573 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is associated with low-grade albuminuria in Chinese adults (change not displayed
    • Lin L, Lu J, Huang X, et al. Nonalcoholic fatty liver disease is associated with low-grade albuminuria in Chinese adults (change not displayed). QJM 2016;109:737-43.
    • (2016) QJM , vol.109 , pp. 737-743
    • Lin, L.1    Lu, J.2    Huang, X.3
  • 105
    • 84988944839 scopus 로고    scopus 로고
    • Fatty liver and chronic kidney disease: Novel mechanistic insights and therapeutic opportunities
    • Musso G, Cassader M, Cohney S, et al. Fatty liver and chronic kidney disease: novel mechanistic insights and therapeutic opportunities. Diabetes Care 2016;39:1830-45.
    • (2016) Diabetes Care , vol.39 , pp. 1830-1845
    • Musso, G.1    Cassader, M.2    Cohney, S.3
  • 107
    • 40049095342 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease predicts chronic kidney disease in nonhypertensive and nondiabetic Korean men
    • Chang Y, Ryu S, Sung E, et al. Nonalcoholic fatty liver disease predicts chronic kidney disease in nonhypertensive and nondiabetic Korean men. Metab Clin Exp 2008;57:569-76.
    • (2008) Metab Clin Exp , vol.57 , pp. 569-576
    • Chang, Y.1    Ryu, S.2    Sung, E.3
  • 108
    • 49649090452 scopus 로고    scopus 로고
    • Increased risk of CKD among type 2 diabetics with nonalcoholic fatty liver disease
    • Targher G, Chonchol M, Bertolini L, et al. Increased risk of CKD among type 2 diabetics with nonalcoholic fatty liver disease. J Am Soc Nephrol 2008;19:1564-70.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1564-1570
    • Targher, G.1    Chonchol, M.2    Bertolini, L.3
  • 109
    • 84901462957 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is independently associated with an increased incidence of chronic kidney disease in patients with type 1 diabetes
    • Targher G, Mantovani A, Pichiri I, et al. Nonalcoholic fatty liver disease is independently associated with an increased incidence of chronic kidney disease in patients with type 1 diabetes. Diabetes Care 2014;37:1729-36.
    • (2014) Diabetes Care , vol.37 , pp. 1729-1736
    • Targher, G.1    Mantovani, A.2    Pichiri, I.3
  • 110
    • 84905401784 scopus 로고    scopus 로고
    • Association of non-Alcoholic fatty liver disease with chronic kidney disease: A systematic review and meta-Analysis
    • Musso G, Gambino R, Tabibian JH, et al. Association of non-Alcoholic fatty liver disease with chronic kidney disease: A systematic review and meta-Analysis. PLoS Med 2014;11:e1001680.
    • (2014) PLoS Med , vol.11 , pp. e1001680
    • Musso, G.1    Gambino, R.2    Tabibian, J.H.3
  • 111
    • 84997181557 scopus 로고    scopus 로고
    • Improvement in liver histology due to lifestyle modification is independently associated with improved kidney function in patients with non-Alcoholic steatohepatitis
    • Vilar-Gomez E, Calzadilla-Bertot L, Friedman SL, et al. Improvement in liver histology due to lifestyle modification is independently associated with improved kidney function in patients with non-Alcoholic steatohepatitis. Aliment Pharmacol Ther 2017;45:332-44.
    • Aliment Pharmacol Ther , vol.2017 , Issue.45 , pp. 332-344
    • Vilar-Gomez, E.1    Calzadilla-Bertot, L.2    Friedman, S.L.3
  • 112
    • 84857046691 scopus 로고    scopus 로고
    • Prevalence of non-Alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese: A population study using protonmagnetic resonance spectroscopy and transient elastography
    • Wong VW, Chu WC, Wong GL, et al. Prevalence of non-Alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese: A population study using protonmagnetic resonance spectroscopy and transient elastography. Gut 2012;61:409-15.
    • (2012) Gut , vol.61 , pp. 409-415
    • Wong, V.W.1    Chu, W.C.2    Wong, G.L.3
  • 113
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
    • Browning JD, Szczepaniak LS, Dobbins R, et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 2004;40:1387-95.
    • (2004) Hepatology , vol.40 , pp. 1387-1395
    • Browning, J.D.1    Szczepaniak, L.S.2    Dobbins, R.3
  • 114
    • 84930401292 scopus 로고    scopus 로고
    • Screening diabetic patients for non-Alcoholic fatty liver disease with controlled attenuation parameter and liver stiffness measurements: A prospective cohort study
    • Kwok R, Choi KC, Wong GL, et al. Screening diabetic patients for non-Alcoholic fatty liver disease with controlled attenuation parameter and liver stiffness measurements: A prospective cohort study. Gut 2016;65:1359-68.
    • (2016) Gut , vol.65 , pp. 1359-1368
    • Kwok, R.1    Choi, K.C.2    Wong, G.L.3
  • 115
    • 84922208434 scopus 로고    scopus 로고
    • Metabolically normal obese people are protected from adverse effects following weight gain
    • Fabbrini E, Yoshino J, Yoshino M, et al. Metabolically normal obese people are protected from adverse effects following weight gain. J Clin Invest 2015;125:787-95.
    • (2015) J Clin Invest , vol.125 , pp. 787-795
    • Fabbrini, E.1    Yoshino, J.2    Yoshino, M.3
  • 116
    • 0031766447 scopus 로고    scopus 로고
    • Prospective study of serum gamma-glutamyltransferase and risk of NIDDM
    • Perry IJ, Wannamethee SG, Shaper AG. Prospective study of serum gamma-glutamyltransferase and risk of NIDDM. Diabetes Care 1998;21:732-7.
    • (1998) Diabetes Care , vol.21 , pp. 732-737
    • Perry, I.J.1    Wannamethee, S.G.2    Shaper, A.G.3
  • 117
    • 84964510429 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is associated with an almost twofold increased risk of incident type 2 diabetes and metabolic syndrome. Evidence from a systematic review and meta-Analysis
    • Ballestri S, Zona S, Targher G, et al. Nonalcoholic fatty liver disease is associated with an almost twofold increased risk of incident type 2 diabetes and metabolic syndrome. Evidence from a systematic review and meta-Analysis. J Gastroenterol Hepatol 2016;31:936-44.
    • (2016) J Gastroenterol Hepatol , vol.31 , pp. 936-944
    • Ballestri, S.1    Zona, S.2    Targher, G.3
  • 118
    • 77953045389 scopus 로고    scopus 로고
    • Nine-year incident diabetes is predicted by fatty liver indices: The French D.E.S.I.R study
    • Group Study DESIR
    • Balkau B, Lange C, Vol S, et al. Group Study DESIR. Nine-year incident diabetes is predicted by fatty liver indices: The French D.E.S.I.R. study. BMC Gastroenterol 2010;10:56.
    • (2010) BMC Gastroenterol , vol.10 , pp. 56
    • Balkau, B.1    Lange, C.2    Vol, S.3
  • 119
    • 84889658153 scopus 로고    scopus 로고
    • Cohort study of non-Alcoholic fatty liver disease, NAFLD fibrosis score, and the risk of incident diabetes in a Korean population
    • Chang Y, Jung HS, Yun KE, et al. Cohort study of non-Alcoholic fatty liver disease, NAFLD fibrosis score, and the risk of incident diabetes in a Korean population. Am J Gastroenterol 2013;108:1861-8.
    • (2013) Am J Gastroenterol , vol.108 , pp. 1861-1868
    • Chang, Y.1    Jung, H.S.2    Yun, K.E.3
  • 120
    • 84959502343 scopus 로고    scopus 로고
    • New risk-scoring system including non-Alcoholic fatty liver disease for predicting incident type 2 diabetes in East China: Shanghai Baosteel Cohort
    • Chen GY, Cao HX, Li F, et al. New risk-scoring system including non-Alcoholic fatty liver disease for predicting incident type 2 diabetes in East China: Shanghai Baosteel Cohort. J Diabetes Investig 2016;7:206-11.
    • (2016) J Diabetes Investig , vol.7 , pp. 206-211
    • Chen, G.Y.1    Cao, H.X.2    Li, F.3
  • 121
    • 84955489581 scopus 로고    scopus 로고
    • The impact of non-Alcoholic fatty liver disease on incident type 2 diabetes mellitus in non-overweight individuals
    • Fukuda T, Hamaguchi M, Kojima T, et al. The impact of non-Alcoholic fatty liver disease on incident type 2 diabetes mellitus in non-overweight individuals. Liver Int 2016;36:275-83.
    • (2016) Liver Int , vol.36 , pp. 275-283
    • Fukuda, T.1    Hamaguchi, M.2    Kojima, T.3
  • 122
    • 41749083027 scopus 로고    scopus 로고
    • Fatty liver is an independent risk factor for the development of Type 2 diabetes in Korean adults
    • Kim CH, Park JY, Lee KU, et al. Fatty liver is an independent risk factor for the development of Type 2 diabetes in Korean adults. Diabet Med 2008;25:476-81.
    • (2008) Diabet Med , vol.25 , pp. 476-481
    • Kim, C.H.1    Park, J.Y.2    Lee, K.U.3
  • 123
    • 84945447081 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease predicts type 2 diabetes mellitus, but not prediabetes, in Xian, China: A five-year cohort study
    • Ming J, Xu S, Gao B, et al. Non-Alcoholic fatty liver disease predicts type 2 diabetes mellitus, but not prediabetes, in Xian, China: A five-year cohort study. Liver Int 2015;35:2401-7.
    • (2015) Liver Int , vol.35 , pp. 2401-2407
    • Ming, J.1    Xu, S.2    Gao, B.3
  • 124
    • 0037267345 scopus 로고    scopus 로고
    • The association of fatty liver and diabetes risk
    • Okamoto M, Takeda Y, Yoda Y, et al. The association of fatty liver and diabetes risk. J Epidemiol 2003;13:15-21.
    • (2003) J Epidemiol , vol.13 , pp. 15-21
    • Okamoto, M.1    Takeda, Y.2    Yoda, Y.3
  • 125
    • 84876105171 scopus 로고    scopus 로고
    • Clinical availability of nonalcoholic fatty liver disease as an early predictor of type 2 diabetes mellitus in Korean men: 5-year prospective cohort study
    • Park SK, Seo MH, Shin HC, et al. Clinical availability of nonalcoholic fatty liver disease as an early predictor of type 2 diabetes mellitus in Korean men: 5-year prospective cohort study. Hepatology 2013;57:1378-83.
    • (2013) Hepatology , vol.57 , pp. 1378-1383
    • Park, S.K.1    Seo, M.H.2    Shin, H.C.3
  • 126
    • 84937858836 scopus 로고    scopus 로고
    • Liver fat, statin use, and incident diabetes: The Multi-Ethnic Study of Atherosclerosis
    • Shah RV, Allison MA, Lima JA, et al. Liver fat, statin use, and incident diabetes: The Multi-Ethnic Study of Atherosclerosis. Atherosclerosis 2015;242:211-17.
    • (2015) Atherosclerosis , vol.242 , pp. 211-217
    • Shah, R.V.1    Allison, M.A.2    Lima, J.A.3
  • 127
    • 79953860268 scopus 로고    scopus 로고
    • Interrelationship between fatty liver and insulin resistance in the development of type 2 diabetes
    • Sung KC, Kim SH. Interrelationship between fatty liver and insulin resistance in the development of type 2 diabetes. J Clin Endocrinol Metab 2011;96:1093-7.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 1093-1097
    • Sung, K.C.1    Kim, S.H.2
  • 128
    • 76149092159 scopus 로고    scopus 로고
    • Fatty liver predicts impaired fasting glucose and type 2 diabetes mellitus in Japanese undergoing a health checkup
    • Yamada T, Fukatsu M, Suzuki S, et al. Fatty liver predicts impaired fasting glucose and type 2 diabetes mellitus in Japanese undergoing a health checkup. J Gastroenterol Hepatol 2010;25:352-6.
    • (2010) J Gastroenterol Hepatol , vol.25 , pp. 352-356
    • Yamada, T.1    Fukatsu, M.2    Suzuki, S.3
  • 129
    • 84962469252 scopus 로고    scopus 로고
    • Independent association between improvement of nonalcoholic fatty liver disease and reduced incidence of type 2 diabetes
    • Yamazaki H, Tsuboya T, Tsuji K, et al. Independent association between improvement of nonalcoholic fatty liver disease and reduced incidence of type 2 diabetes. Diabetes Care 2015;38:1673-9.
    • (2015) Diabetes Care , vol.38 , pp. 1673-1679
    • Yamazaki, H.1    Tsuboya, T.2    Tsuji, K.3
  • 130
    • 84883686923 scopus 로고    scopus 로고
    • Resolution of fatty liver and risk of incident diabetes
    • Sung KC, Wild SH, Byrne CD. Resolution of fatty liver and risk of incident diabetes. J Clin Endocrinol Metab 2013;98:3637-43.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 3637-3643
    • Sung, K.C.1    Wild, S.H.2    Byrne, C.D.3
  • 131
    • 84986190544 scopus 로고    scopus 로고
    • Transient remission of nonalcoholic fatty liver disease decreases the risk of incident type 2 diabetes mellitus in Japanese men
    • Fukuda T, Hamaguchi M, Kojima T, et al. Transient remission of nonalcoholic fatty liver disease decreases the risk of incident type 2 diabetes mellitus in Japanese men. Eur J Gastroenterol Hepatol 2016;28:1443-9.
    • (2016) Eur J Gastroenterol Hepatol , vol.28 , pp. 1443-1449
    • Fukuda, T.1    Hamaguchi, M.2    Kojima, T.3
  • 132
    • 84862075971 scopus 로고    scopus 로고
    • Combined influence of insulin resistance, overweight/obesity, and fatty liver as risk factors for type 2 diabetes
    • Sung KC, Jeong WS, Wild SH, et al. Combined influence of insulin resistance, overweight/obesity, and fatty liver as risk factors for type 2 diabetes. Diabetes Care 2012;35:717-22.
    • (2012) Diabetes Care , vol.35 , pp. 717-722
    • Sung, K.C.1    Jeong, W.S.2    Wild, S.H.3
  • 133
    • 79956074978 scopus 로고    scopus 로고
    • Combined effect of nonalcoholic fatty liver disease and impaired fasting glucose on the development of type 2 diabetes: A 4-year retrospective longitudinal study
    • Bae JC, Rhee EJ, Lee WY, et al. Combined effect of nonalcoholic fatty liver disease and impaired fasting glucose on the development of type 2 diabetes: A 4-year retrospective longitudinal study. Diabetes Care 2011;34:727-9.
    • (2011) Diabetes Care , vol.34 , pp. 727-729
    • Bae, J.C.1    Rhee, E.J.2    Lee, W.Y.3
  • 134
    • 84979598547 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease with and without metabolic syndrome: Different long-Term outcomes
    • Käräjämäki AJ, Bloigu R, Kauma H, et al. Non-Alcoholic fatty liver disease with and without metabolic syndrome: different long-Term outcomes. Metab Clin Exp 2017;66:55-63.
    • (2017) Metab Clin Exp , vol.66 , pp. 55-63
    • Käräjämäki, A.J.1    Bloigu, R.2    Kauma, H.3
  • 135
    • 84875259571 scopus 로고    scopus 로고
    • Increased risk of type 2 diabetes in subjects with both elevated liver enzymes and ultrasonographically diagnosed nonalcoholic fatty liver disease: A 4-year longitudinal study
    • Choi JH, Rhee EJ, Bae JC, et al. Increased risk of type 2 diabetes in subjects with both elevated liver enzymes and ultrasonographically diagnosed nonalcoholic fatty liver disease: A 4-year longitudinal study. Arch Med Res 2013;44:115-20.
    • (2013) Arch Med Res , vol.44 , pp. 115-120
    • Choi, J.H.1    Rhee, E.J.2    Bae, J.C.3
  • 136
    • 84993945319 scopus 로고    scopus 로고
    • The relationship between nonalcoholic fatty liver disease and retinopathy in NHANES III
    • Lin TY, Chen YJ, Chen WL, et al. The relationship between nonalcoholic fatty liver disease and retinopathy in NHANES III. PLoS One 2016;11:e0165970.
    • (2016) PLoS One , vol.11 , pp. e0165970
    • Lin, T.Y.1    Chen, Y.J.2    Chen, W.L.3
  • 137
    • 77953893410 scopus 로고    scopus 로고
    • Dissociation between intrahepatic triglyceride content and insulin resistance in familial hypobetalipoproteinemia
    • Amaro A, Fabbrini E, Kars M, et al. Dissociation between intrahepatic triglyceride content and insulin resistance in familial hypobetalipoproteinemia. Gastroenterology 2010;139:149-53.
    • (2010) Gastroenterology , vol.139 , pp. 149-153
    • Amaro, A.1    Fabbrini, E.2    Kars, M.3
  • 138
    • 84862491622 scopus 로고    scopus 로고
    • Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant
    • Palmer CN, Maglio C, Pirazzi C, et al. Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant. PLoS ONE 2012;7:e39362.
    • (2012) PLoS ONE , vol.7 , pp. e39362
    • Palmer, C.N.1    Maglio, C.2    Pirazzi, C.3
  • 139
    • 84962661546 scopus 로고    scopus 로고
    • European Association for the Study of the Liver (EASL); European Association for the Study of Diabetes (EASD); European Association for the Study of Obesity (EASO) EASL-EASD-EASO Clinical Practice Guidelines for the management of non-Alcoholic fatty liver disease
    • European Association for the Study of the Liver (EASL); European Association for the Study of Diabetes (EASD); European Association for the Study of Obesity (EASO). EASL-EASD-EASO Clinical Practice Guidelines for the management of non-Alcoholic fatty liver disease. J Hepatol 2016;64:1388-402.
    • (2016) J Hepatol , vol.64 , pp. 1388-1402
  • 140
    • 77954424925 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease increases risk of death among patients with diabetes: A community-based cohort study
    • Adams LA, Harmsen S, St Sauver JL, et al. Nonalcoholic fatty liver disease increases risk of death among patients with diabetes: A community-based cohort study. Am J Gastroenterol 2010;105:1567-73.
    • (2010) Am J Gastroenterol , vol.105 , pp. 1567-1573
    • Adams, L.A.1    Harmsen, S.2    St Sauver, J.L.3
  • 141
    • 84881007386 scopus 로고    scopus 로고
    • Patients with nonalcoholic fatty liver disease have higher risk of colorectal adenoma after negative baseline colonoscopy
    • Huang KW, Leu HB, Wang YJ, et al. Patients with nonalcoholic fatty liver disease have higher risk of colorectal adenoma after negative baseline colonoscopy. Colorectal Dis 2013;15:830-5.
    • (2013) Colorectal Dis , vol.15 , pp. 830-835
    • Huang, K.W.1    Leu, H.B.2    Wang, Y.J.3
  • 142
    • 84923205820 scopus 로고    scopus 로고
    • Association between nonalcoholic fatty liver disease and colorectal adenoma: A systematic review and meta-Analysis
    • Ding W, Fan J, Qin J. Association between nonalcoholic fatty liver disease and colorectal adenoma: A systematic review and meta-Analysis. Int J Clin Exp Med 2015;8:322-33.
    • (2015) Int J Clin Exp Med , vol.8 , pp. 322-333
    • Ding, W.1    Fan, J.2    Qin, J.3
  • 143
    • 84995756376 scopus 로고    scopus 로고
    • Association between nonalcoholic fatty liver disease and colorectal adenoma: A systemic review and meta-Analysis
    • Shen H, Lipka S, Kumar A, et al. Association between nonalcoholic fatty liver disease and colorectal adenoma: A systemic review and meta-Analysis. J Gastrointest Oncol 2014;5:440-6.
    • (2014) J Gastrointest Oncol , vol.5 , pp. 440-446
    • Shen, H.1    Lipka, S.2    Kumar, A.3
  • 144
    • 79955804203 scopus 로고    scopus 로고
    • High prevalence of colorectal neoplasm in patients with non-Alcoholic steatohepatitis
    • Wong VW, Wong GL, Tsang SW, et al. High prevalence of colorectal neoplasm in patients with non-Alcoholic steatohepatitis. Gut 2011;60:829-36.
    • (2011) Gut , vol.60 , pp. 829-836
    • Wong, V.W.1    Wong, G.L.2    Tsang, S.W.3
  • 145
    • 80052308377 scopus 로고    scopus 로고
    • Prevalence of colonic adenomas in patients with nonalcoholic fatty liver disease
    • Touzin NT, Bush KN, Williams CD, et al. Prevalence of colonic adenomas in patients with nonalcoholic fatty liver disease. Therap Adv Gastroenterol 2011;4:169-76.
    • (2011) Therap Adv Gastroenterol , vol.4 , pp. 169-176
    • Touzin, N.T.1    Bush, K.N.2    Williams, C.D.3
  • 146
    • 85002406523 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver diseases and risk of colorectal neoplasia
    • Ahn JS, Sinn DH, Min YW, et al. Non-Alcoholic fatty liver diseases and risk of colorectal neoplasia. Aliment Pharmacol Ther 2017;45:345-53.
    • Aliment Pharmacol Ther , vol.2017 , Issue.45 , pp. 345-353
    • Ahn, J.S.1    Sinn, D.H.2    Min, Y.W.3
  • 147
    • 84155178375 scopus 로고    scopus 로고
    • Colorectal neoplasms in relation to non-Alcoholic fatty liver disease in Korean women: A retrospective cohort study
    • Lee YI, Lim YS, Park HS. Colorectal neoplasms in relation to non-Alcoholic fatty liver disease in Korean women: A retrospective cohort study. J Gastroenterol Hepatol 2012;27:91-5.
    • (2012) J Gastroenterol Hepatol , vol.27 , pp. 91-95
    • Lee, Y.I.1    Lim, Y.S.2    Park, H.S.3
  • 148
    • 84905702697 scopus 로고    scopus 로고
    • Increased risk of colorectal malignant neoplasm in patients with nonalcoholic fatty liver disease: A large study
    • Lin XF, Shi KQ, You J, et al. Increased risk of colorectal malignant neoplasm in patients with nonalcoholic fatty liver disease: A large study. Mol Biol Rep 2014;41:2989-97.
    • (2014) Mol Biol Rep , vol.41 , pp. 2989-2997
    • Lin, X.F.1    Shi, K.Q.2    You, J.3
  • 149
    • 84967278705 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease and extra-hepatic cancers
    • Sanna C, Rosso C, Marietti M, et al. Non-Alcoholic fatty liver disease and extra-hepatic cancers. Int J Mol Sci 2016;17:E717.
    • (2016) Int J Mol Sci , Issue.17 , pp. E717
    • Sanna, C.1    Rosso, C.2    Marietti, M.3
  • 150
    • 84937416763 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and decreased bone mineral density is there a link?
    • Targher G, Lonardo A, Rossini M. Nonalcoholic fatty liver disease and decreased bone mineral density: is there a link? J Endocrinol Invest 2015;38:817-25.
    • (2015) J Endocrinol Invest , vol.38 , pp. 817-825
    • Targher, G.1    Lonardo, A.2    Rossini, M.3
  • 151
    • 83855161556 scopus 로고    scopus 로고
    • Non-Alcoholic fatty liver disease is associated with low bone mineral density in obese children
    • Pardee PE, Dunn W, Schwimmer JB. Non-Alcoholic fatty liver disease is associated with low bone mineral density in obese children. Aliment Pharmacol Ther 2012;35:248-54.
    • (2012) Aliment Pharmacol Ther , vol.35 , pp. 248-254
    • Pardee, P.E.1    Dunn, W.2    Schwimmer, J.B.3
  • 152
    • 85034400406 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and osteoporosis: A systematic review and meta-Analysis
    • Upala S, Jaruvongvanich V, Wijarnpreecha K, et al. Nonalcoholic fatty liver disease and osteoporosis: A systematic review and meta-Analysis. J Bone Miner Metab 2016.
    • (2016) J Bone Miner Metab
    • Upala, S.1    Jaruvongvanich, V.2    Wijarnpreecha, K.3
  • 153
    • 84958888896 scopus 로고    scopus 로고
    • The association of liver fat content and serum alanine aminotransferase with bone mineral density in middle-Aged and elderly Chinese men and postmenopausal women
    • Xia MF, Lin HD, Yan HM, et al. The association of liver fat content and serum alanine aminotransferase with bone mineral density in middle-Aged and elderly Chinese men and postmenopausal women. J Transl Med 2016;14:11.
    • (2016) J Transl Med , vol.14 , pp. 11
    • Xia, M.F.1    Lin, H.D.2    Yan, H.M.3
  • 154
    • 84991706053 scopus 로고    scopus 로고
    • Association between bone mineral density and nonalcoholic fatty liver disease in Korean adults
    • Lee SH, Yun JM, Kim SH, et al. Association between bone mineral density and nonalcoholic fatty liver disease in Korean adults. J Endocrinol Invest 2016;39:1329-36.
    • (2016) J Endocrinol Invest , vol.39 , pp. 1329-1336
    • Lee, S.H.1    Yun, J.M.2    Kim, S.H.3
  • 155
    • 84957848024 scopus 로고    scopus 로고
    • Association of nonalcoholic fatty liver disease with bone mineral density and serum osteocalcin levels in Korean men
    • Yang HJ, Shim SG, Ma BO, et al. Association of nonalcoholic fatty liver disease with bone mineral density and serum osteocalcin levels in Korean men. Eur J Gastroenterol Hepatol 2016;28:338-44.
    • (2016) Eur J Gastroenterol Hepatol , vol.28 , pp. 338-344
    • Yang, H.J.1    Shim, S.G.2    Ma, B.O.3
  • 156
    • 84861989656 scopus 로고    scopus 로고
    • Association between nonalcoholic fatty liver disease (NAFLD) and osteoporotic fracture in middle-Aged and elderly Chinese
    • Li M, Xu Y, Xu M, et al. Association between nonalcoholic fatty liver disease (NAFLD) and osteoporotic fracture in middle-Aged and elderly Chinese. J Clin Endocrinol Metab 2012;97:2033-8.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 2033-2038
    • Li, M.1    Xu, Y.2    Xu, M.3
  • 158
    • 84857355693 scopus 로고    scopus 로고
    • Serum interleukin 1 receptor antagonist as an independent marker of non-Alcoholic steatohepatitis in humans
    • Pihlajämaki J, Kuulasmaa T, Kaminska D, et al. Serum interleukin 1 receptor antagonist as an independent marker of non-Alcoholic steatohepatitis in humans. J Hepatol 2012;56:663-70.
    • (2012) J Hepatol , vol.56 , pp. 663-670
    • Pihlajämaki, J.1    Kuulasmaa, T.2    Kaminska, D.3
  • 159
    • 84987903536 scopus 로고    scopus 로고
    • Interleukin-1 and inflammasomes in alcoholic liver disease/acute alcoholic hepatitis and nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
    • Tilg H, Moschen AR, Szabo G. Interleukin-1 and inflammasomes in alcoholic liver disease/acute alcoholic hepatitis and nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. Hepatology 2016;64:955-65.
    • (2016) Hepatology , vol.64 , pp. 955-965
    • Tilg, H.1    Moschen, A.R.2    Szabo, G.3
  • 160
    • 84874045511 scopus 로고    scopus 로고
    • The origins and drivers of insulin resistance
    • Johnson AM, Olefsky JM. The origins and drivers of insulin resistance. Cell 2013;152:673-84.
    • (2013) Cell , vol.152 , pp. 673-684
    • Johnson, A.M.1    Olefsky, J.M.2
  • 161
    • 78049522194 scopus 로고    scopus 로고
    • Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis
    • Tilg H, Moschen AR. Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis. Hepatology 2010;52:1836-46.
    • (2010) Hepatology , vol.52 , pp. 1836-1846
    • Tilg, H.1    Moschen, A.R.2
  • 162
    • 0030735542 scopus 로고    scopus 로고
    • Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-Alpha, in vivo
    • Mohamed-Ali V, Goodrick S, Rawesh A, et al. Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-Alpha, in vivo. J Clin Endocrinol Metab 1997;82:4196-200.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4196-4200
    • Mohamed-Ali, V.1    Goodrick, S.2    Rawesh, A.3
  • 163
    • 84992374677 scopus 로고    scopus 로고
    • Lack of adipocyte AMPK exacerbates insulin resistance and hepatic steatosis through brown and beige adipose tissue function
    • Mottillo EP, Desjardins EM, Crane JD, et al. Lack of adipocyte AMPK exacerbates insulin resistance and hepatic steatosis through brown and beige adipose tissue function. Cell Metab 2016;24:118-29.
    • (2016) Cell Metab , vol.24 , pp. 118-129
    • Mottillo, E.P.1    Desjardins, E.M.2    Crane, J.D.3
  • 164
    • 84980332386 scopus 로고    scopus 로고
    • Lipodystrophy due to adipose tissue-specific insulin receptor knockout results in progressive NAFLD
    • Softic S, Boucher J, Solheim MH, et al. Lipodystrophy due to adipose tissue-specific insulin receptor knockout results in progressive NAFLD. Diabetes 2016;65:2187-200.
    • (2016) Diabetes , vol.65 , pp. 2187-2200
    • Softic, S.1    Boucher, J.2    Solheim, M.H.3
  • 165
    • 85007622282 scopus 로고    scopus 로고
    • Adipose type i interferon signalling protects against metabolic dysfunction
    • [Epub ahead of print 23 Dec 2016]
    • Wieser V, Adolph TE, Grander C, et al. Adipose type I interferon signalling protects against metabolic dysfunction. Gut 2016. doi: 10.1136/gutjnl-2016-313155. [Epub ahead of print 23 Dec 2016].
    • (2016) Gut
    • Wieser, V.1    Adolph, T.E.2    Grander, C.3
  • 166
    • 79959201412 scopus 로고    scopus 로고
    • Human nutrition, the gut microbiome and the immune system
    • Kau AL, Ahern PP, Griffin NW, et al. Human nutrition, the gut microbiome and the immune system. Nature 2011;474:327-36.
    • (2011) Nature , vol.474 , pp. 327-336
    • Kau, A.L.1    Ahern, P.P.2    Griffin, N.W.3
  • 167
    • 84928381097 scopus 로고    scopus 로고
    • Food, immunity, and the microbiome
    • Tilg H, Moschen AR. Food, immunity, and the microbiome. Gastroenterology 2015;148:1107-19.
    • (2015) Gastroenterology , vol.148 , pp. 1107-1119
    • Tilg, H.1    Moschen, A.R.2
  • 168
    • 84876787121 scopus 로고    scopus 로고
    • Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells
    • Kleinewietfeld M, Manzel A, Titze J, et al. Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells. Nature 2013;496:518-22.
    • (2013) Nature , vol.496 , pp. 518-522
    • Kleinewietfeld, M.1    Manzel, A.2    Titze, J.3
  • 169
    • 80055019374 scopus 로고    scopus 로고
    • Fatty acids and inflammation: The cutting edge between food and pharma
    • Calder PC. Fatty acids and inflammation: The cutting edge between food and pharma. Eur J Pharmacol 2011;668(Suppl 1):S50-8.
    • (2011) Eur J Pharmacol , vol.668 , pp. S50-S58
    • Calder, P.C.1
  • 170
    • 84922708862 scopus 로고    scopus 로고
    • Intestinal permeability-A new target for disease prevention and therapy
    • Bischoff SC, Barbara G, Buurman W, et al. Intestinal permeability-A new target for disease prevention and therapy. BMC Gastroenterol 2014;14: 189.
    • (2014) BMC Gastroenterol , vol.14 , pp. 189
    • Bischoff, S.C.1    Barbara, G.2    Buurman, W.3
  • 171
    • 84989859198 scopus 로고    scopus 로고
    • Loss of junctional adhesion molecule a promotes severe steatohepatitis in mice on a diet high in saturated fat, fructose, and cholesterol
    • Rahman K, Desai C, Iyer SS, et al. Loss of junctional adhesion molecule a promotes severe steatohepatitis in mice on a diet high in saturated fat, fructose, and cholesterol. Gastroenterology 2016;151:733-46.e12.
    • (2016) Gastroenterology , vol.151 , pp. 733-46e12
    • Rahman, K.1    Desai, C.2    Iyer, S.S.3
  • 172
    • 84863413720 scopus 로고    scopus 로고
    • A high-fat diet is associated with endotoxemia that originates from the gut
    • Pendyala S, Walker JM, Holt PR. A high-fat diet is associated with endotoxemia that originates from the gut. Gastroenterology 2012;142:1100-1.e2.
    • (2012) Gastroenterology , vol.142 , pp. 1100-1100e2
    • Pendyala, S.1    Walker, J.M.2    Holt, P.R.3
  • 173
    • 84863436944 scopus 로고    scopus 로고
    • Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/-mice
    • Devkota S, Wang Y, Musch MW, et al. Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/-mice. Nature 2012;487:104-8.
    • (2012) Nature , vol.487 , pp. 104-108
    • Devkota, S.1    Wang, Y.2    Musch, M.W.3
  • 174
    • 79953733693 scopus 로고    scopus 로고
    • Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
    • Wang Z, Klipfell E, Bennett BJ, et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature 2011;472:57-63.
    • (2011) Nature , vol.472 , pp. 57-63
    • Wang, Z.1    Klipfell, E.2    Bennett, B.J.3
  • 175
    • 84969612602 scopus 로고    scopus 로고
    • Preventive effects of citrulline on Western diet-induced non-Alcoholic fatty liver disease in rats
    • Jegatheesan P, Beutheu S, Freese K, et al. Preventive effects of citrulline on Western diet-induced non-Alcoholic fatty liver disease in rats. Br J Nutr 2016;116:191-203.
    • (2016) Br J Nutr , vol.116 , pp. 191-203
    • Jegatheesan, P.1    Beutheu, S.2    Freese, K.3
  • 176
    • 84994553261 scopus 로고    scopus 로고
    • Gut microbiome and liver diseases
    • Tilg H, Cani PD, Mayer EA. Gut microbiome and liver diseases. Gut 2016;65:2035-44.
    • (2016) Gut , vol.65 , pp. 2035-2044
    • Tilg, H.1    Cani, P.D.2    Mayer, E.A.3
  • 177
    • 84971663701 scopus 로고    scopus 로고
    • Gut microbiota profiling of pediatric NAFLD and obese patients unveiled by an integrated meta-omics based approach
    • Del Chierico F, Nobili V, Vernocchi P, et al. Gut microbiota profiling of pediatric NAFLD and obese patients unveiled by an integrated meta-omics based approach. Hepatology 2017;65:451-64.
    • Hepatology , vol.2017 , Issue.65 , pp. 451-464
    • Del Chierico, F.1    Nobili, V.2    Vernocchi, P.3
  • 178
    • 84954288595 scopus 로고    scopus 로고
    • The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota
    • Boursier J, Mueller O, Barret M, et al. The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota. Hepatology 2016;63:764-75.
    • (2016) Hepatology , vol.63 , pp. 764-775
    • Boursier, J.1    Mueller, O.2    Barret, M.3
  • 179
    • 84879888338 scopus 로고    scopus 로고
    • Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
    • Yoshimoto S, Loo TM, Atarashi K, et al. Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome. Nature 2013;499:97-101.
    • (2013) Nature , vol.499 , pp. 97-101
    • Yoshimoto, S.1    Loo, T.M.2    Atarashi, K.3
  • 180
    • 84924690678 scopus 로고    scopus 로고
    • Gut microbiome development along the colorectal adenoma-carcinoma sequence
    • Feng Q, Liang S, Jia H, et al. Gut microbiome development along the colorectal adenoma-carcinoma sequence. Nat Commun 2015;6:6528.
    • (2015) Nat Commun , vol.6 , pp. 6528
    • Feng, Q.1    Liang, S.2    Jia, H.3
  • 181
    • 0034676629 scopus 로고    scopus 로고
    • Cytokines in alcoholic and nonalcoholic steatohepatitis
    • Tilg H, Diehl AM. Cytokines in alcoholic and nonalcoholic steatohepatitis. N Engl J Med 2000;343:1467-76.
    • (2000) N Engl J Med , vol.343 , pp. 1467-1476
    • Tilg, H.1    Diehl, A.M.2
  • 182
    • 14644427890 scopus 로고    scopus 로고
    • Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
    • Cai D, Yuan M, Frantz DF, et al. Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med 2005;11:183-90.
    • (2005) Nat Med , vol.11 , pp. 183-190
    • Cai, D.1    Yuan, M.2    Frantz, D.F.3
  • 183
    • 20044387026 scopus 로고    scopus 로고
    • IKK-beta links inflammation to obesity-induced insulin resistance
    • Arkan MC, Hevener AL, Greten FR, et al. IKK-beta links inflammation to obesity-induced insulin resistance. Nat Med 2005;11:191-8.
    • (2005) Nat Med , vol.11 , pp. 191-198
    • Arkan, M.C.1    Hevener, A.L.2    Greten, F.R.3
  • 184
    • 84875221877 scopus 로고    scopus 로고
    • Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus
    • Kiechl S, Wittmann J, Giaccari A, et al. Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus. Nat Med 2013;19:358-63.
    • (2013) Nat Med , vol.19 , pp. 358-363
    • Kiechl, S.1    Wittmann, J.2    Giaccari, A.3
  • 185
    • 85016727543 scopus 로고    scopus 로고
    • Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism
    • doi: gutjnl-2015-310904. [Epub ahead of print 5 May 2016]
    • Duparc T, Plovier H, Marrachelli VG, et al. Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism. Gut 2016. doi: gutjnl-2015-310904. [Epub ahead of print 5 May 2016].
    • (2016) Gut
    • Duparc, T.1    Plovier, H.2    Marrachelli, V.G.3
  • 186
    • 84958580773 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and hepatocellular carcinoma
    • Zoller H, Tilg H. Nonalcoholic fatty liver disease and hepatocellular carcinoma. Metab Clin Exp 2016;65:1151-60.
    • (2016) Metab Clin Exp , vol.65 , pp. 1151-1160
    • Zoller, H.1    Tilg, H.2
  • 187
    • 74549167737 scopus 로고    scopus 로고
    • Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
    • Park EJ, Lee JH, Yu GY, et al. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell 2010;140:197-208.
    • (2010) Cell , vol.140 , pp. 197-208
    • Park, E.J.1    Lee, J.H.2    Yu, G.Y.3
  • 188
    • 10844220730 scopus 로고    scopus 로고
    • Adiponectin and its receptors in non-Alcoholic steatohepatitis
    • Kaser S, Moschen A, Cayon A, et al. Adiponectin and its receptors in non-Alcoholic steatohepatitis. Gut 2005;54:117-21.
    • (2005) Gut , vol.54 , pp. 117-121
    • Kaser, S.1    Moschen, A.2    Cayon, A.3
  • 189
    • 33748992313 scopus 로고    scopus 로고
    • Adipocytokines: Mediators linking adipose tissue, inflammation and immunity
    • Tilg H, Moschen AR. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol 2006;6:772-83.
    • (2006) Nat Rev Immunol , vol.6 , pp. 772-783
    • Tilg, H.1    Moschen, A.R.2
  • 190
    • 27944506001 scopus 로고    scopus 로고
    • Low plasma adiponectin levels and risk of colorectal cancer in men: A prospective study
    • Wei EK, Giovannucci E, Fuchs CS, et al. Low plasma adiponectin levels and risk of colorectal cancer in men: A prospective study. J Natl Cancer Inst 2005;97:1688-94.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1688-1694
    • Wei, E.K.1    Giovannucci, E.2    Fuchs, C.S.3
  • 191
    • 77954353057 scopus 로고    scopus 로고
    • Interaction between adiponectin and leptin influences the risk of colorectal adenoma
    • Yamaji T, Iwasaki M, Sasazuki S, et al. Interaction between adiponectin and leptin influences the risk of colorectal adenoma. Cancer Res 2010;70:5430-7.
    • (2010) Cancer Res , vol.70 , pp. 5430-5437
    • Yamaji, T.1    Iwasaki, M.2    Sasazuki, S.3
  • 192
    • 84964894113 scopus 로고    scopus 로고
    • Prediagnosis plasma adiponectin in relation to colorectal cancer risk according to KRAS mutation status
    • Inamura K, Song M, Jung S, et al. Prediagnosis plasma adiponectin in relation to colorectal cancer risk according to KRAS mutation status. J Natl Cancer Inst 2016;108.
    • (2016) J Natl Cancer Inst , vol.108
    • Inamura, K.1    Song, M.2    Jung, S.3
  • 193
    • 84955487817 scopus 로고    scopus 로고
    • Progression of carotid vascular damage and cardiovascular events in non-Alcoholic fatty liver disease patients compared to the general population during 10 years of follow-up
    • Fracanzani AL, Tiraboschi S, Pisano G, et al. Progression of carotid vascular damage and cardiovascular events in non-Alcoholic fatty liver disease patients compared to the general population during 10 years of follow-up. Atherosclerosis 2016;246:208-13.
    • (2016) Atherosclerosis , vol.246 , pp. 208-213
    • Fracanzani, A.L.1    Tiraboschi, S.2    Pisano, G.3
  • 194
    • 84991826595 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is independently associated with an increased incidence of cardiovascular disease in adult patients with type 1 diabetes
    • Mantovani A, Mingolla L, Rigolon R, et al. Nonalcoholic fatty liver disease is independently associated with an increased incidence of cardiovascular disease in adult patients with type 1 diabetes. Int J Cardiol 2016;225:387-91.
    • (2016) Int J Cardiol , vol.225 , pp. 387-391
    • Mantovani, A.1    Mingolla, L.2    Rigolon, R.3
  • 195
    • 84963864348 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and incident cardiac events: The multi-ethnic study of atherosclerosis
    • Zeb I, Li D, Budoff MJ, et al. Nonalcoholic fatty liver disease and incident cardiac events: The multi-ethnic study of atherosclerosis. J Am Coll Cardiol 2016;67:1965-6.
    • (2016) J Am Coll Cardiol , vol.67 , pp. 1965-1966
    • Zeb, I.1    Li, D.2    Budoff, M.J.3
  • 196
    • 77649226704 scopus 로고    scopus 로고
    • Relationship of non-Alcoholic fatty liver disease to colorectal adenomatous polyps
    • Hwang ST, Cho YK, Park JH, et al. Relationship of non-Alcoholic fatty liver disease to colorectal adenomatous polyps. J Gastroenterol Hepatol 2010;25:562-7.
    • (2010) J Gastroenterol Hepatol , vol.25 , pp. 562-567
    • Hwang, S.T.1    Cho, Y.K.2    Park, J.H.3
  • 197
    • 79959344354 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: An independent risk factor for colorectal neoplasia
    • Stadlmayr A, Aigner E, Steger B, et al. Nonalcoholic fatty liver disease: An independent risk factor for colorectal neoplasia. J Intern Med 2011;270:41-9.
    • (2011) J Intern Med , vol.270 , pp. 41-49
    • Stadlmayr, A.1    Aigner, E.2    Steger, B.3
  • 198
    • 84995751139 scopus 로고    scopus 로고
    • Increased risk of colorectal polyps in patients with non-Alcoholic fatty liver disease undergoing liver transplant evaluation
    • Bhatt BD, Lukose T, Siegel AB, et al. Increased risk of colorectal polyps in patients with non-Alcoholic fatty liver disease undergoing liver transplant evaluation. J Gastrointest Oncol 2015;6:459-68.
    • (2015) J Gastrointest Oncol , vol.6 , pp. 459-468
    • Bhatt, B.D.1    Lukose, T.2    Siegel, A.B.3
  • 199
    • 84949634791 scopus 로고    scopus 로고
    • Absence of non-Alcoholic fatty liver disease in the presence of insulin resistance is a strong predictor for colorectal carcinoma
    • Basyigit S, Uzman M, Kefeli A, et al. Absence of non-Alcoholic fatty liver disease in the presence of insulin resistance is a strong predictor for colorectal carcinoma. Int J Clin Exp Med 2015;8:18601-10.
    • (2015) Int J Clin Exp Med , vol.8 , pp. 18601-18610
    • Basyigit, S.1    Uzman, M.2    Kefeli, A.3


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