Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Palmer, Colin N A ^a   Maglio, Cristina ^b   Pirazzi, Carlo ^b   Burza, Maria Antonella ^b   Adiels, Martin ^b   Burch, Lindsay ^a   Donnelly, Louise A ^a   Colhoun, Helen ^a   Doney, Alexander S ^a   Dillon, John F ^a   Pearson, Ewan R ^a   McCarthy, Mark ^c   Hattersley, Andrew T ^d   Frayling, Tim ^d   Morris, Andrew D ^a   Peltonen, Markku ^e   Svensson, Per Arne ^b   Jacobson, Peter ^b   Borén, Jan ^b   Sjöström, Lars ^b   Carlsson, Lena M S ^b   Romeo, Stefano ^b,f   more..

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF EXETER   (United Kingdom)

^e NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^f UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LIPID; TRIACYLGLYCEROL;

ADULT; ALLELE; ARTICLE; BARIATRIC SURGERY; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY; FEMALE; FOLLOW UP; GENE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE ENVIRONMENT INTERACTION; HETEROZYGOTE; HIGH RISK POPULATION; HUMAN; INSULIN RESISTANCE; INTERVENTION STUDY; LIPID STORAGE; MAJOR CLINICAL STUDY; MALE; METABOLIC PARAMETERS; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING 3 GENE; POPULATION BASED CASE CONTROL STUDY; PROSPECTIVE STUDY; TRIACYLGLYCEROL BLOOD LEVEL; VALIDATION PROCESS;

ADULT; ALLELES; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; DISEASE SUSCEPTIBILITY; FEMALE; GENE-ENVIRONMENT INTERACTION; GENOTYPE; HUMANS; INSULIN RESISTANCE; LIPASE; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MUTATION; OBESITY; QUANTITATIVE TRAIT, HERITABLE; RISK FACTORS; TRIGLYCERIDES; WEIGHT LOSS;

EID: 84862491622     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039362     Document Type: Article

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