Melatonin protects against blood-brain barrier damage by inhibiting the TLR4/NF-κB signaling pathway after LPS treatment in neonatal rats

Oncotarget

Volumn 8, Issue 19, 2017, Pages 31638-31654

  Hu, Yingying ^a   Wang, Zhouguang ^a   Pan, Shulin ^a   Zhang, Hongyu ^a   Fang, Mingchu ^a   Jiang, Huai ^a   Zhang, Hao ^a   Gao, Zhengzheng ^a   Xu, Kebin ^a   Li, Zhenmao ^a   Xiao, Jian ^a   Lin, Zhenlang ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Blood brain barrier; Hypoxic ischemic and inflammatory; Melatonin; TLR4 NF B; White matter injury

Indexed keywords

ADHERENS JUNCTION PROTEIN; BRAIN PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MELATONIN; TIGHT JUNCTION PROTEIN; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; LIPOPOLYSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTOSIS; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG EFFECT; GLIOSIS; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IN VITRO STUDY; IN VIVO STUDY; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NEWBORN; NONHUMAN; PERICYTE; PROTEIN DEGRADATION; RAT; SIGNAL TRANSDUCTION; TREATMENT DURATION; WHITE MATTER; WHITE MATTER INJURY; ADHERENS JUNCTION; ANIMAL; BIOLOGICAL MODEL; BRAIN INJURY; CYTOLOGY; DISEASE MODEL; IMMUNOLOGY; INFLAMMATION; METABOLISM; MICROGLIA; PATHOLOGY; PERMEABILITY; TIGHT JUNCTION;

ADHERENS JUNCTIONS; ANIMALS; ANIMALS, NEWBORN; BLOOD-BRAIN BARRIER; BRAIN INJURIES; DISEASE MODELS, ANIMAL; INFLAMMATION; LIPOPOLYSACCHARIDES; MELATONIN; MICROGLIA; MODELS, BIOLOGICAL; NF-KAPPA B; PERICYTES; PERMEABILITY; RATS; SIGNAL TRANSDUCTION; TIGHT JUNCTIONS; TOLL-LIKE RECEPTOR 4; WHITE MATTER;

EID: 85019142014     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.15780     Document Type: Article

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