Aldehyde dehydrogenase 1 activity in the developing human pancreas modulates retinoic acid signalling in mediating islet differentiation and survival

Diabetologia

Volumn 57, Issue 4, 2014, Pages 754-764

  Li, Jinming ^a   Feng, Zhi C ^a   Yeung, Frances S H ^a   Wong, Melanie R M ^a   Oakie, Amanda ^a   Fellows, George F ^a   Goodyer, Cynthia G ^b   Hess, David A ^a,c   Wang, Rennian ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

Aldehyde dehydrogenase 1; Human fetal pancreas; Pancreatic endocrine cell differentiation; Retinoic acid signalling

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE ISOENZYME 1; CASPASE; PHOSPHATIDYLINOSITOL 3 KINASE; RETINOIC ACID; RETINOIC ACID RECEPTOR; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; ENDOCRINE CELL; ENZYME ACTIVITY; FETUS; HUMAN; HUMAN CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; WESTERN BLOTTING;

BLOTTING, WESTERN; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; ISLETS OF LANGERHANS; ISOENZYMES; PANCREAS; PREGNANCY; RETINAL DEHYDROGENASE; TRETINOIN;

EID: 84896096082     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-3147-y     Document Type: Article

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