Inhibition of Gsk3β activity improves β-cell function in c-KitWv/+ male mice

Laboratory Investigation

Volumn 92, Issue 4, 2012, Pages 543-555

  Feng, Zhi Chao ^a   Donnelly, Lisa ^a   Li, Jinming ^a   Krishnamurthy, Mansa ^a   Riopel, Matthew ^a   Wang, Rennian ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Akt Gsk3 cyclin D1 signaling pathway; Gsk3 kinase inhibitor; cell regeneration

Indexed keywords

1 AZAKENPAULLONE; BETA CATENIN; CYCLIN D1; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; KI 67 ANTIGEN; PAULLONE DERIVATIVE; PROTEIN KINASE B; STEM CELL FACTOR RECEPTOR; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; HISTOLOGY; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

EID: 84859316462     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2011.200     Document Type: Article

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