-
1
-
-
84985911227
-
Early-life origins of chronic obstructive pulmonary disease
-
Martinez, FD, Early-life origins of chronic obstructive pulmonary disease. N Engl J Med 375 (2016), 871–878.
-
(2016)
N Engl J Med
, vol.375
, pp. 871-878
-
-
Martinez, F.D.1
-
2
-
-
84937969384
-
Intravenous augmentation treatment and lung density in severe alpha1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial
-
Chapman, KR, Burdon, JG, Piitulainen, E, et al. Intravenous augmentation treatment and lung density in severe alpha1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial. Lancet 386 (2015), 360–368.
-
(2015)
Lancet
, vol.386
, pp. 360-368
-
-
Chapman, K.R.1
Burdon, J.G.2
Piitulainen, E.3
-
3
-
-
84973882932
-
Indacaterol-glycopyrronium versus salmeterol-fluticasone for COPD
-
Wedzicha, JA, Banerji, D, Chapman, KR, et al. Indacaterol-glycopyrronium versus salmeterol-fluticasone for COPD. N Engl J Med 374 (2016), 2222–2234.
-
(2016)
N Engl J Med
, vol.374
, pp. 2222-2234
-
-
Wedzicha, J.A.1
Banerji, D.2
Chapman, K.R.3
-
4
-
-
84979994372
-
A phase III randomised controlled trial of single-dose triple therapy in COPD: the IMPACT protocol
-
Pascoe, SJ, Lipson, DA, Locantore, N, et al. A phase III randomised controlled trial of single-dose triple therapy in COPD: the IMPACT protocol. Eur Respir J 48 (2016), 320–330.
-
(2016)
Eur Respir J
, vol.48
, pp. 320-330
-
-
Pascoe, S.J.1
Lipson, D.A.2
Locantore, N.3
-
5
-
-
85013300009
-
GOLD 2017 Global Strategy for the Diagnosis, Management and Prevention of COPD
-
(accessed Nov 26, 2016).
-
GOLD 2017 Global Strategy for the Diagnosis, Management and Prevention of COPD. http://goldcopd.org/gold-2017-global-strategy-diagnosis-management-prevention-copd/ (accessed Nov 26, 2016).
-
-
-
-
6
-
-
84994092049
-
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015
-
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet 388 (2016), 1545–1602.
-
(2016)
Lancet
, vol.388
, pp. 1545-1602
-
-
-
7
-
-
85019974371
-
Global and regional estimates of COPD prevalence: systematic review and meta-analysis
-
Adeloye, D, Chua, S, Lee, C, et al. Global and regional estimates of COPD prevalence: systematic review and meta-analysis. J Glob Health, 5, 2015, 020415.
-
(2015)
J Glob Health
, vol.5
, pp. 020415
-
-
Adeloye, D.1
Chua, S.2
Lee, C.3
-
8
-
-
80052747314
-
Lifetime risk of developing chronic obstructive pulmonary disease: a longitudinal population study
-
Gershon, AS, Warner, L, Cascagnette, P, Victor, JC, To, T, Lifetime risk of developing chronic obstructive pulmonary disease: a longitudinal population study. Lancet 378 (2011), 991–996.
-
(2011)
Lancet
, vol.378
, pp. 991-996
-
-
Gershon, A.S.1
Warner, L.2
Cascagnette, P.3
Victor, J.C.4
To, T.5
-
9
-
-
84943410734
-
Determinants of underdiagnosis of COPD in national and international surveys
-
Lamprecht, B, Soriano, JB, Studnicka, M, et al. Determinants of underdiagnosis of COPD in national and international surveys. Chest 148 (2015), 971–985.
-
(2015)
Chest
, vol.148
, pp. 971-985
-
-
Lamprecht, B.1
Soriano, J.B.2
Studnicka, M.3
-
10
-
-
33846207657
-
Chronic respiratory diseases. Burden of COPD
-
(accessed Nov 19, 2016).
-
World Health Organization. Chronic respiratory diseases. Burden of COPD. http://www.who.int/respiratory/copd/burden/en/ (accessed Nov 19, 2016).
-
-
-
-
11
-
-
37149022825
-
Gender and chronic obstructive pulmonary disease: why it matters
-
Han, MK, Postma, D, Mannino, DM, et al. Gender and chronic obstructive pulmonary disease: why it matters. Am J Respir Crit Care Med 176 (2007), 1179–1184.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 1179-1184
-
-
Han, M.K.1
Postma, D.2
Mannino, D.M.3
-
12
-
-
77953689989
-
Gender differences in COPD: are women more susceptible to smoking effects than men?
-
Sorheim, IC, Johannessen, A, Gulsvik, A, Bakke, PS, Silverman, EK, DeMeo, DL, Gender differences in COPD: are women more susceptible to smoking effects than men?. Thorax 65 (2010), 480–485.
-
(2010)
Thorax
, vol.65
, pp. 480-485
-
-
Sorheim, I.C.1
Johannessen, A.2
Gulsvik, A.3
Bakke, P.S.4
Silverman, E.K.5
DeMeo, D.L.6
-
13
-
-
84958087450
-
Incidence of airflow limitation in subjects 65-100 years of age
-
Luoto, JA, Elmstahl, S, Wollmer, P, Pihlsgard, M, Incidence of airflow limitation in subjects 65-100 years of age. Eur Respir J 47 (2016), 461–472.
-
(2016)
Eur Respir J
, vol.47
, pp. 461-472
-
-
Luoto, J.A.1
Elmstahl, S.2
Wollmer, P.3
Pihlsgard, M.4
-
14
-
-
84994158650
-
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015
-
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet 388 (2016), 1459–1544.
-
(2016)
Lancet
, vol.388
, pp. 1459-1544
-
-
-
15
-
-
13444250953
-
The effects of a smoking cessation intervention on 14.5-year mortality: a randomized clinical trial
-
Anthonisen, NR, Skeans, MA, Wise, RA, Manfreda, J, Kanner, RE, Connett, JE, The effects of a smoking cessation intervention on 14.5-year mortality: a randomized clinical trial. Ann Intern Med 142 (2005), 233–239.
-
(2005)
Ann Intern Med
, vol.142
, pp. 233-239
-
-
Anthonisen, N.R.1
Skeans, M.A.2
Wise, R.A.3
Manfreda, J.4
Kanner, R.E.5
Connett, J.E.6
-
16
-
-
33847172367
-
Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease
-
Calverley, PM, Anderson, JA, Celli, B, et al. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med 356 (2007), 775–789.
-
(2007)
N Engl J Med
, vol.356
, pp. 775-789
-
-
Calverley, P.M.1
Anderson, J.A.2
Celli, B.3
-
17
-
-
84988835518
-
Lung function abnormalities in smokers with ischemic heart disease
-
Franssen, FM, Soriano, JB, Roche, N, et al. Lung function abnormalities in smokers with ischemic heart disease. Am J Respir Crit Care Med 194 (2016), 568–576.
-
(2016)
Am J Respir Crit Care Med
, vol.194
, pp. 568-576
-
-
Franssen, F.M.1
Soriano, J.B.2
Roche, N.3
-
18
-
-
84929011928
-
Global and regional trends in COPD mortality, 1990–2010
-
Burney, PG, Patel, J, Newson, R, Minelli, C, Naghavi, M, Global and regional trends in COPD mortality, 1990–2010. Eur Respir J 45 (2015), 1239–1247.
-
(2015)
Eur Respir J
, vol.45
, pp. 1239-1247
-
-
Burney, P.G.1
Patel, J.2
Newson, R.3
Minelli, C.4
Naghavi, M.5
-
19
-
-
34548222188
-
Global burden of COPD: risk factors, prevalence, and future trends
-
Mannino, DM, Buist, AS, Global burden of COPD: risk factors, prevalence, and future trends. Lancet 370 (2007), 765–773.
-
(2007)
Lancet
, vol.370
, pp. 765-773
-
-
Mannino, D.M.1
Buist, A.S.2
-
20
-
-
85060773959
-
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
-
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet 388 (2016), 1659–1724.
-
(2016)
Lancet
, vol.388
, pp. 1659-1724
-
-
-
21
-
-
84896979007
-
Global Health Observatory data. Prevalence of tobacco smoking
-
(accessed Feb 5, 2017).
-
WHO. Global Health Observatory data. Prevalence of tobacco smoking. http://www.who.int/gho/tobacco/use/en/ (accessed Feb 5, 2017).
-
-
-
-
22
-
-
85018894967
-
World Health statistics 2016 data visualizations dashboard. Tobacco control. Region data
-
(accessed Feb 5, 2017).
-
WHO. World Health statistics 2016 data visualizations dashboard. Tobacco control. Region data. http://apps.who.int/gho/data/view.sdg.3-a-data-reg?lang=en (accessed Feb 5, 2017).
-
-
-
-
23
-
-
69149102202
-
Chronic obstructive pulmonary disease in non-smokers
-
Salvi, SS, Barnes, PJ, Chronic obstructive pulmonary disease in non-smokers. Lancet 374 (2009), 733–743.
-
(2009)
Lancet
, vol.374
, pp. 733-743
-
-
Salvi, S.S.1
Barnes, P.J.2
-
24
-
-
84930419573
-
An official American Thoracic Society/European Respiratory Society statement: research questions in COPD
-
Celli, BR, Decramer, M, Wedzicha, JA, et al. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD. Eur Respir Rev 24 (2015), 159–172.
-
(2015)
Eur Respir Rev
, vol.24
, pp. 159-172
-
-
Celli, B.R.1
Decramer, M.2
Wedzicha, J.A.3
-
25
-
-
84922394855
-
FEV1 decline in patients with chronic obstructive pulmonary disease associated with biomass exposure
-
Ramirez-Venegas, A, Sansores, RH, Quintana-Carrillo, RH, et al. FEV1 decline in patients with chronic obstructive pulmonary disease associated with biomass exposure. Am J Respir Crit Care Med 190 (2014), 996–1002.
-
(2014)
Am J Respir Crit Care Med
, vol.190
, pp. 996-1002
-
-
Ramirez-Venegas, A.1
Sansores, R.H.2
Quintana-Carrillo, R.H.3
-
26
-
-
33645526100
-
Hyperinflation, dyspnea, and exercise intolerance in chronic obstructive pulmonary disease
-
O'Donnell, DE, Hyperinflation, dyspnea, and exercise intolerance in chronic obstructive pulmonary disease. Proc Am Thorac Soc 3 (2006), 180–184.
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 180-184
-
-
O'Donnell, D.E.1
-
27
-
-
84941247915
-
Clinical and radiologic disease in smokers with normal spirometry
-
Regan, EA, Lynch, DA, Curran-Everett, D, et al. Clinical and radiologic disease in smokers with normal spirometry. JAMA Intern Med 175 (2015), 1539–1549.
-
(2015)
JAMA Intern Med
, vol.175
, pp. 1539-1549
-
-
Regan, E.A.1
Lynch, D.A.2
Curran-Everett, D.3
-
28
-
-
84966650988
-
Clinical significance of symptoms in smokers with preserved pulmonary function
-
Woodruff, PG, Barr, RG, Bleecker, E, et al. Clinical significance of symptoms in smokers with preserved pulmonary function. N Engl J Med 374 (2016), 1811–1821.
-
(2016)
N Engl J Med
, vol.374
, pp. 1811-1821
-
-
Woodruff, P.G.1
Barr, R.G.2
Bleecker, E.3
-
29
-
-
84943376336
-
Molecular mechanisms underlying variations in lung function: a systems genetics analysis
-
Obeidat, M, Hao, K, Bosse, Y, et al. Molecular mechanisms underlying variations in lung function: a systems genetics analysis. Lancet Respir Med 3 (2015), 782–795.
-
(2015)
Lancet Respir Med
, vol.3
, pp. 782-795
-
-
Obeidat, M.1
Hao, K.2
Bosse, Y.3
-
30
-
-
84943428582
-
Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank
-
Wain, LV, Shrine, N, Miller, S, et al. Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. Lancet Respir Med 3 (2015), 769–781.
-
(2015)
Lancet Respir Med
, vol.3
, pp. 769-781
-
-
Wain, L.V.1
Shrine, N.2
Miller, S.3
-
31
-
-
84943415424
-
Elucidating COPD pathogenesis by large-scale genetic analyses
-
Brusselle, GG, Bracke, KR, Elucidating COPD pathogenesis by large-scale genetic analyses. Lancet Respir Med 3 (2015), 737–739.
-
(2015)
Lancet Respir Med
, vol.3
, pp. 737-739
-
-
Brusselle, G.G.1
Bracke, K.R.2
-
32
-
-
84955340692
-
Physiological impairment in mild COPD
-
O'Donnell, DE, Neder, JA, Elbehairy, AF, Physiological impairment in mild COPD. Respirology 21 (2016), 211–223.
-
(2016)
Respirology
, vol.21
, pp. 211-223
-
-
O'Donnell, D.E.1
Neder, J.A.2
Elbehairy, A.F.3
-
33
-
-
84859424158
-
Chronic obstructive pulmonary disease
-
Decramer, M, Janssens, W, Miravitlles, M, Chronic obstructive pulmonary disease. Lancet 379 (2012), 1341–1351.
-
(2012)
Lancet
, vol.379
, pp. 1341-1351
-
-
Decramer, M.1
Janssens, W.2
Miravitlles, M.3
-
34
-
-
84961287979
-
COPD-bronchiectasis overlap syndrome
-
Hurst, JR, Elborn, JS, De Soyza, A, COPD-bronchiectasis overlap syndrome. Eur Respir J 45 (2015), 310–313.
-
(2015)
Eur Respir J
, vol.45
, pp. 310-313
-
-
Hurst, J.R.1
Elborn, J.S.2
De Soyza, A.3
-
35
-
-
84862833566
-
Small-airway obstruction and emphysema in chronic obstructive pulmonary disease
-
McDonough, JE, Yuan, R, Suzuki, M, et al. Small-airway obstruction and emphysema in chronic obstructive pulmonary disease. N Engl J Med 365 (2011), 1567–1575.
-
(2011)
N Engl J Med
, vol.365
, pp. 1567-1575
-
-
McDonough, J.E.1
Yuan, R.2
Suzuki, M.3
-
36
-
-
84936762052
-
Lung-function trajectories leading to chronic obstructive pulmonary disease
-
Lange, P, Celli, B, Agusti, A, et al. Lung-function trajectories leading to chronic obstructive pulmonary disease. N Engl J Med 373 (2015), 111–122.
-
(2015)
N Engl J Med
, vol.373
, pp. 111-122
-
-
Lange, P.1
Celli, B.2
Agusti, A.3
-
37
-
-
84996554709
-
Asthma transition from childhood into adulthood
-
published online Sept 22
-
Fuchs, O, Bahmer, T, Rabe, KF, von Mutius, E, Asthma transition from childhood into adulthood. Lancet Respir Med, 2016 published online Sept 22 http://dx.doi.org/10.1016/S2213-2600(16)30187-4.
-
(2016)
Lancet Respir Med
-
-
Fuchs, O.1
Bahmer, T.2
Rabe, K.F.3
von Mutius, E.4
-
38
-
-
84942474807
-
The asthma-COPD overlap syndrome
-
Postma, DS, Rabe, KF, The asthma-COPD overlap syndrome. N Engl J Med 373 (2015), 1241–1249.
-
(2015)
N Engl J Med
, vol.373
, pp. 1241-1249
-
-
Postma, D.S.1
Rabe, K.F.2
-
39
-
-
34248371233
-
Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease
-
Demedts, IK, Bracke, KR, Van Pottelberge, G, et al. Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 175 (2007), 998–1005.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 998-1005
-
-
Demedts, I.K.1
Bracke, K.R.2
Van Pottelberge, G.3
-
40
-
-
0141928029
-
Chronic obstructive pulmonary disease: molecular and cellular mechanisms
-
Barnes, PJ, Shapiro, SD, Pauwels, RA, Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J 22 (2003), 672–688.
-
(2003)
Eur Respir J
, vol.22
, pp. 672-688
-
-
Barnes, P.J.1
Shapiro, S.D.2
Pauwels, R.A.3
-
41
-
-
80052706801
-
New insights into the immunology of chronic obstructive pulmonary disease
-
Brusselle, GG, Joos, GF, Bracke, KR, New insights into the immunology of chronic obstructive pulmonary disease. Lancet 378 (2011), 1015–1026.
-
(2011)
Lancet
, vol.378
, pp. 1015-1026
-
-
Brusselle, G.G.1
Joos, G.F.2
Bracke, K.R.3
-
42
-
-
24144433461
-
Oligoclonal CD4+ T cells in the lungs of patients with severe emphysema
-
Sullivan, AK, Simonian, PL, Falta, MT, et al. Oligoclonal CD4+ T cells in the lungs of patients with severe emphysema. Am J Respir Crit Care Med 172 (2005), 590–596.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 590-596
-
-
Sullivan, A.K.1
Simonian, P.L.2
Falta, M.T.3
-
43
-
-
33645321836
-
Cigarette smoke-induced emphysema: a role for the B cell?
-
van der Strate, BW, Postma, DS, Brandsma, CA, et al. Cigarette smoke-induced emphysema: a role for the B cell?. Am J Respir Crit Care Med 173 (2006), 751–758.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 751-758
-
-
van der Strate, B.W.1
Postma, D.S.2
Brandsma, C.A.3
-
44
-
-
70349118100
-
New paradigms in the pathogenesis of chronic obstructive pulmonary disease I
-
MacNee, W, Tuder, RM, New paradigms in the pathogenesis of chronic obstructive pulmonary disease I. Proc Am Thorac Soc 6 (2009), 527–531.
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 527-531
-
-
MacNee, W.1
Tuder, R.M.2
-
45
-
-
33749841717
-
Alveolar cell senescence in patients with pulmonary emphysema
-
Tsuji, T, Aoshiba, K, Nagai, A, Alveolar cell senescence in patients with pulmonary emphysema. Am J Respir Crit Care Med 174 (2006), 886–893.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 886-893
-
-
Tsuji, T.1
Aoshiba, K.2
Nagai, A.3
-
46
-
-
9744272376
-
Cigarette smoke induces senescence in alveolar epithelial cells
-
Tsuji, T, Aoshiba, K, Nagai, A, Cigarette smoke induces senescence in alveolar epithelial cells. Am J Respir Cell Mol Biol 31 (2004), 643–649.
-
(2004)
Am J Respir Cell Mol Biol
, vol.31
, pp. 643-649
-
-
Tsuji, T.1
Aoshiba, K.2
Nagai, A.3
-
47
-
-
84929466240
-
Accelerated ageing of the lung in COPD: new concepts
-
Mercado, N, Ito, K, Barnes, PJ, Accelerated ageing of the lung in COPD: new concepts. Thorax 70 (2015), 482–489.
-
(2015)
Thorax
, vol.70
, pp. 482-489
-
-
Mercado, N.1
Ito, K.2
Barnes, P.J.3
-
48
-
-
84959564407
-
Pulmonary CT and MRI phenotypes that help explain chronic pulmonary obstruction disease pathophysiology and outcomes
-
Hoffman, EA, Lynch, DA, Barr, RG, van Beek, EJ, Parraga, G, Pulmonary CT and MRI phenotypes that help explain chronic pulmonary obstruction disease pathophysiology and outcomes. J Magn Reson Imaging 43 (2016), 544–557.
-
(2016)
J Magn Reson Imaging
, vol.43
, pp. 544-557
-
-
Hoffman, E.A.1
Lynch, D.A.2
Barr, R.G.3
van Beek, E.J.4
Parraga, G.5
-
49
-
-
84938118974
-
CT-definable subtypes of chronic obstructive pulmonary disease: a statement of the Fleischner Society
-
Lynch, DA, Austin, JH, Hogg, JC, et al. CT-definable subtypes of chronic obstructive pulmonary disease: a statement of the Fleischner Society. Radiology 277 (2015), 192–205.
-
(2015)
Radiology
, vol.277
, pp. 192-205
-
-
Lynch, D.A.1
Austin, J.H.2
Hogg, J.C.3
-
50
-
-
78651431729
-
Systemic manifestations of COPD
-
Nussbaumer-Ochsner, Y, Rabe, KF, Systemic manifestations of COPD. Chest 139 (2011), 165–173.
-
(2011)
Chest
, vol.139
, pp. 165-173
-
-
Nussbaumer-Ochsner, Y.1
Rabe, K.F.2
-
51
-
-
84880040954
-
Chronic obstructive pulmonary disease and comorbidities
-
Decramer, M, Janssens, W, Chronic obstructive pulmonary disease and comorbidities. Lancet Respir Med 1 (2013), 73–83.
-
(2013)
Lancet Respir Med
, vol.1
, pp. 73-83
-
-
Decramer, M.1
Janssens, W.2
-
52
-
-
84971607470
-
Management of chronic obstructive pulmonary disease beyond the lungs
-
Vanfleteren, LE, Spruit, MA, Wouters, EF, Franssen, FM, Management of chronic obstructive pulmonary disease beyond the lungs. Lancet Respir Med 4 (2016), 911–924.
-
(2016)
Lancet Respir Med
, vol.4
, pp. 911-924
-
-
Vanfleteren, L.E.1
Spruit, M.A.2
Wouters, E.F.3
Franssen, F.M.4
-
53
-
-
84939464236
-
Risk of cardiovascular comorbidity in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
-
Chen, W, Thomas, J, Sadatsafavi, M, FitzGerald, JM, Risk of cardiovascular comorbidity in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis. Lancet Respir Med 3 (2015), 631–639.
-
(2015)
Lancet Respir Med
, vol.3
, pp. 631-639
-
-
Chen, W.1
Thomas, J.2
Sadatsafavi, M.3
FitzGerald, J.M.4
-
54
-
-
85002670293
-
Chronic obstructive pulmonary disease and cardiac diseases: an urgent need for integrated care
-
Roversi, S, Fabbri, LM, Sin, DD, Hawkins, NM, Agusti, A, Chronic obstructive pulmonary disease and cardiac diseases: an urgent need for integrated care. Am J Respir Crit Care Med 194 (2016), 1319–1336.
-
(2016)
Am J Respir Crit Care Med
, vol.194
, pp. 1319-1336
-
-
Roversi, S.1
Fabbri, L.M.2
Sin, D.D.3
Hawkins, N.M.4
Agusti, A.5
-
55
-
-
53549108591
-
Common origins of lung cancer and COPD
-
Houghton, AM, Mouded, M, Shapiro, SD, Common origins of lung cancer and COPD. Nat Med 14 (2008), 1023–1024.
-
(2008)
Nat Med
, vol.14
, pp. 1023-1024
-
-
Houghton, A.M.1
Mouded, M.2
Shapiro, S.D.3
-
56
-
-
84875466646
-
Mechanistic links between COPD and lung cancer
-
Houghton, AM, Mechanistic links between COPD and lung cancer. Nat Rev Cancer 13 (2013), 233–245.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 233-245
-
-
Houghton, A.M.1
-
57
-
-
84941309580
-
The relationship between COPD and lung cancer
-
Durham, AL, Adcock, IM, The relationship between COPD and lung cancer. Lung Cancer 90 (2015), 121–127.
-
(2015)
Lung Cancer
, vol.90
, pp. 121-127
-
-
Durham, A.L.1
Adcock, I.M.2
-
58
-
-
84964422577
-
Identification of COPD patients at high risk for lung cancer mortality using the COPD-LUCSS-DLCO
-
de Torres, JP, Marin, JM, Casanova, C, et al. Identification of COPD patients at high risk for lung cancer mortality using the COPD-LUCSS-DLCO. Chest 149 (2016), 936–942.
-
(2016)
Chest
, vol.149
, pp. 936-942
-
-
de Torres, J.P.1
Marin, J.M.2
Casanova, C.3
-
59
-
-
84922311554
-
Lung cancer in patients with chronic obstructive pulmonary disease. Development and validation of the COPD Lung Cancer Screening Score
-
de Torres, JP, Wilson, DO, Sanchez-Salcedo, P, et al. Lung cancer in patients with chronic obstructive pulmonary disease. Development and validation of the COPD Lung Cancer Screening Score. Am J Respir Crit Care Med 191 (2015), 285–291.
-
(2015)
Am J Respir Crit Care Med
, vol.191
, pp. 285-291
-
-
de Torres, J.P.1
Wilson, D.O.2
Sanchez-Salcedo, P.3
-
60
-
-
80054690890
-
Lung cancer in patients with chronic obstructive pulmonary disease—incidence and predicting factors
-
de Torres, JP, Marin, JM, Casanova, C, Cote, C, et al. Lung cancer in patients with chronic obstructive pulmonary disease—incidence and predicting factors. Am J Respir Crit Care Med 184 (2011), 913–919.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 913-919
-
-
de Torres, J.P.1
Marin, J.M.2
Casanova, C.3
Cote, C.4
-
61
-
-
37549021114
-
Assessing the relationship between lung cancer risk and emphysema detected on low-dose CT of the chest
-
de Torres, JP, Bastarrika, G, Wisnivesky, JP, et al. Assessing the relationship between lung cancer risk and emphysema detected on low-dose CT of the chest. Chest 132 (2007), 1932–1938.
-
(2007)
Chest
, vol.132
, pp. 1932-1938
-
-
de Torres, J.P.1
Bastarrika, G.2
Wisnivesky, J.P.3
-
62
-
-
84927792203
-
Improving selection criteria for lung cancer screening. The potential role of emphysema
-
Sanchez-Salcedo, P, Wilson, DO, de Torres, JP, et al. Improving selection criteria for lung cancer screening. The potential role of emphysema. Am J Respir Crit Care Med 191 (2015), 924–931.
-
(2015)
Am J Respir Crit Care Med
, vol.191
, pp. 924-931
-
-
Sanchez-Salcedo, P.1
Wilson, D.O.2
de Torres, J.P.3
-
63
-
-
84875847989
-
Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease
-
Vanfleteren, LE, Spruit, MA, Groenen, M, et al. Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 187 (2013), 728–735.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 728-735
-
-
Vanfleteren, L.E.1
Spruit, M.A.2
Groenen, M.3
-
64
-
-
70350088412
-
The metabolic syndrome in patients with chronic bronchitis and COPD: frequency and associated consequences for systemic inflammation and physical inactivity
-
Watz, H, Waschki, B, Kirsten, A, et al. The metabolic syndrome in patients with chronic bronchitis and COPD: frequency and associated consequences for systemic inflammation and physical inactivity. Chest 136 (2009), 1039–1046.
-
(2009)
Chest
, vol.136
, pp. 1039-1046
-
-
Watz, H.1
Waschki, B.2
Kirsten, A.3
-
65
-
-
37149042861
-
Arterial stiffness is independently associated with emphysema severity in patients with chronic obstructive pulmonary disease
-
McAllister, DA, Maclay, JD, Mills, NL, et al. Arterial stiffness is independently associated with emphysema severity in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 176 (2007), 1208–1214.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 1208-1214
-
-
McAllister, D.A.1
Maclay, J.D.2
Mills, N.L.3
-
66
-
-
85009773793
-
Peripheral artery disease and its clinical relevance in patients with chronic obstructive pulmonary disease in the COPD and Systemic Consequences–Comorbidities Network Study
-
Houben-Wilke, S, Jorres, RA, Bals, R, et al. Peripheral artery disease and its clinical relevance in patients with chronic obstructive pulmonary disease in the COPD and Systemic Consequences–Comorbidities Network Study. Am J Respir Crit Care Med 195 (2017), 189–197.
-
(2017)
Am J Respir Crit Care Med
, vol.195
, pp. 189-197
-
-
Houben-Wilke, S.1
Jorres, R.A.2
Bals, R.3
-
67
-
-
84904065630
-
Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality
-
Williams, MC, Murchison, JT, Edwards, LD, et al. Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality. Thorax 69 (2014), 718–723.
-
(2014)
Thorax
, vol.69
, pp. 718-723
-
-
Williams, M.C.1
Murchison, J.T.2
Edwards, L.D.3
-
68
-
-
84945292650
-
Airflow limitation and histology shift in the National Lung Screening Trial. The NLST-ACRIN Cohort Substudy
-
Young, RP, Duan, F, Chiles, C, et al. Airflow limitation and histology shift in the National Lung Screening Trial. The NLST-ACRIN Cohort Substudy. Am J Respir Crit Care Med 192 (2015), 1060–1067.
-
(2015)
Am J Respir Crit Care Med
, vol.192
, pp. 1060-1067
-
-
Young, R.P.1
Duan, F.2
Chiles, C.3
-
69
-
-
0034063821
-
Smoking cessation and lung function in mild-to-moderate chronic obstructive pulmonary disease. The Lung Health Study
-
Scanlon, PD, Connett, JE, Waller, LA, Altose, MD, Bailey, WC, Buist, AS, Smoking cessation and lung function in mild-to-moderate chronic obstructive pulmonary disease. The Lung Health Study. Am J Respir Crit Care Med 161 (2000), 381–390.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 381-390
-
-
Scanlon, P.D.1
Connett, J.E.2
Waller, L.A.3
Altose, M.D.4
Bailey, W.C.5
Buist, A.S.6
-
70
-
-
84937404002
-
Statement on smoking cessation in COPD and other pulmonary diseases and in smokers with comorbidities who find it difficult to quit
-
Jimenez-Ruiz, CA, Andreas, S, Lewis, KE, et al. Statement on smoking cessation in COPD and other pulmonary diseases and in smokers with comorbidities who find it difficult to quit. Eur Respir J 46 (2015), 61–79.
-
(2015)
Eur Respir J
, vol.46
, pp. 61-79
-
-
Jimenez-Ruiz, C.A.1
Andreas, S.2
Lewis, K.E.3
-
71
-
-
70349468017
-
Improved biomass stove intervention in rural Mexico: impact on the respiratory health of women
-
Romieu, I, Riojas-Rodriguez, H, Marron-Mares, AT, Schilmann, A, Perez-Padilla, R, Masera, O, Improved biomass stove intervention in rural Mexico: impact on the respiratory health of women. Am J Respir Crit Care Med 180 (2009), 649–656.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 649-656
-
-
Romieu, I.1
Riojas-Rodriguez, H.2
Marron-Mares, A.T.3
Schilmann, A.4
Perez-Padilla, R.5
Masera, O.6
-
72
-
-
77956031239
-
Long-term effectiveness and cost-effectiveness of smoking cessation interventions in patients with COPD
-
Hoogendoorn, M, Feenstra, TL, Hoogenveen, RT, Rutten-van Molken, MP, Long-term effectiveness and cost-effectiveness of smoking cessation interventions in patients with COPD. Thorax 65 (2010), 711–718.
-
(2010)
Thorax
, vol.65
, pp. 711-718
-
-
Hoogendoorn, M.1
Feenstra, T.L.2
Hoogenveen, R.T.3
Rutten-van Molken, M.P.4
-
73
-
-
77950178503
-
Influenza vaccine for patients with chronic obstructive pulmonary disease
-
CD002733.
-
Poole, PJ, Chacko, E, Wood-Baker, RW, Cates, CJ, Influenza vaccine for patients with chronic obstructive pulmonary disease. Cochrane Database Syst Rev, 2006 CD002733.
-
(2006)
Cochrane Database Syst Rev
-
-
Poole, P.J.1
Chacko, E.2
Wood-Baker, R.W.3
Cates, C.J.4
-
74
-
-
79952062000
-
Injectable vaccines for preventing pneumococcal infection in patients with chronic obstructive pulmonary disease
-
CD001390.
-
Walters, JA, Smith, S, Poole, P, Granger, RH, Wood-Baker, R, Injectable vaccines for preventing pneumococcal infection in patients with chronic obstructive pulmonary disease. Cochrane Database Syst Rev, 2010 CD001390.
-
(2010)
Cochrane Database Syst Rev
-
-
Walters, J.A.1
Smith, S.2
Poole, P.3
Granger, R.H.4
Wood-Baker, R.5
-
75
-
-
33748480212
-
Regular physical activity reduces hospital admission and mortality in chronic obstructive pulmonary disease: a population based cohort study
-
Garcia-Aymerich, J, Lange, P, Benet, M, Schnohr, P, Anto, JM, Regular physical activity reduces hospital admission and mortality in chronic obstructive pulmonary disease: a population based cohort study. Thorax 61 (2006), 772–778.
-
(2006)
Thorax
, vol.61
, pp. 772-778
-
-
Garcia-Aymerich, J.1
Lange, P.2
Benet, M.3
Schnohr, P.4
Anto, J.M.5
-
76
-
-
84938873999
-
Disease progression and changes in physical activity in patients with chronic obstructive pulmonary disease
-
Waschki, B, Kirsten, AM, Holz, O, et al. Disease progression and changes in physical activity in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 192 (2015), 295–306.
-
(2015)
Am J Respir Crit Care Med
, vol.192
, pp. 295-306
-
-
Waschki, B.1
Kirsten, A.M.2
Holz, O.3
-
77
-
-
80051523309
-
Physical activity is the strongest predictor of all-cause mortality in patients with COPD: a prospective cohort study
-
Waschki, B, Kirsten, A, Holz, O, et al. Physical activity is the strongest predictor of all-cause mortality in patients with COPD: a prospective cohort study. Chest 140 (2011), 331–342.
-
(2011)
Chest
, vol.140
, pp. 331-342
-
-
Waschki, B.1
Kirsten, A.2
Holz, O.3
-
78
-
-
84916244647
-
An official European Respiratory Society statement on physical activity in COPD
-
Watz, H, Pitta, F, Rochester, CL, et al. An official European Respiratory Society statement on physical activity in COPD. Eur Respir J 44 (2014), 1521–1537.
-
(2014)
Eur Respir J
, vol.44
, pp. 1521-1537
-
-
Watz, H.1
Pitta, F.2
Rochester, C.L.3
-
79
-
-
59649127166
-
Physical activity in patients with COPD
-
Watz, H, Waschki, B, Meyer, T, Magnussen, H, Physical activity in patients with COPD. Eur Respir J 33 (2009), 262–272.
-
(2009)
Eur Respir J
, vol.33
, pp. 262-272
-
-
Watz, H.1
Waschki, B.2
Meyer, T.3
Magnussen, H.4
-
80
-
-
84945562150
-
Pulmonary rehabilitation and physical activity in patients with chronic obstructive pulmonary disease
-
Spruit, MA, Pitta, F, McAuley, E, ZuWallack, RL, Nici, L, Pulmonary rehabilitation and physical activity in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 192 (2015), 924–933.
-
(2015)
Am J Respir Crit Care Med
, vol.192
, pp. 924-933
-
-
Spruit, M.A.1
Pitta, F.2
McAuley, E.3
ZuWallack, R.L.4
Nici, L.5
-
81
-
-
84928794287
-
Aclidinium improves exercise endurance, dyspnea, lung hyperinflation, and physical activity in patients with COPD: a randomized, placebo-controlled, crossover trial
-
Beeh, KM, Watz, H, Puente-Maestu, L, et al. Aclidinium improves exercise endurance, dyspnea, lung hyperinflation, and physical activity in patients with COPD: a randomized, placebo-controlled, crossover trial. BMC Pulm Med, 14, 2014, 209.
-
(2014)
BMC Pulm Med
, vol.14
, pp. 209
-
-
Beeh, K.M.1
Watz, H.2
Puente-Maestu, L.3
-
82
-
-
84974839268
-
Effects of indacaterol/glycopyrronium (QVA149) on lung hyperinflation and physical activity in patients with moderate to severe COPD: a randomised, placebo-controlled, crossover study (the MOVE Study)
-
Watz, H, Mailander, C, Baier, M, Kirsten, A, Effects of indacaterol/glycopyrronium (QVA149) on lung hyperinflation and physical activity in patients with moderate to severe COPD: a randomised, placebo-controlled, crossover study (the MOVE Study). BMC Pulm Med, 16, 2016, 95.
-
(2016)
BMC Pulm Med
, vol.16
, pp. 95
-
-
Watz, H.1
Mailander, C.2
Baier, M.3
Kirsten, A.4
-
83
-
-
84908066729
-
Indacaterol improves lung hyperinflation and physical activity in patients with moderate chronic obstructive pulmonary disease—a randomized, multicenter, double-blind, placebo-controlled study
-
Watz, H, Krippner, F, Kirsten, A, Magnussen, H, Vogelmeier, C, Indacaterol improves lung hyperinflation and physical activity in patients with moderate chronic obstructive pulmonary disease—a randomized, multicenter, double-blind, placebo-controlled study. BMC Pulm Med, 14, 2014, 158.
-
(2014)
BMC Pulm Med
, vol.14
, pp. 158
-
-
Watz, H.1
Krippner, F.2
Kirsten, A.3
Magnussen, H.4
Vogelmeier, C.5
-
84
-
-
80053563435
-
Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study
-
Wen, CP, Wai, JP, Tsai, MK, et al. Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study. Lancet 378 (2011), 1244–1253.
-
(2011)
Lancet
, vol.378
, pp. 1244-1253
-
-
Wen, C.P.1
Wai, J.P.2
Tsai, M.K.3
-
85
-
-
84964809688
-
The minimal important difference in physical activity in patients with COPD
-
Demeyer, H, Burtin, C, Hornikx, M, et al. The minimal important difference in physical activity in patients with COPD. PLoS One, 11, 2016, e0154587.
-
(2016)
PLoS One
, vol.11
, pp. e0154587
-
-
Demeyer, H.1
Burtin, C.2
Hornikx, M.3
-
86
-
-
84886418056
-
An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation
-
Spruit, MA, Singh, SJ, Garvey, C, et al. An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med 188 (2013), e13–e64.
-
(2013)
Am J Respir Crit Care Med
, vol.188
, pp. e13-e64
-
-
Spruit, M.A.1
Singh, S.J.2
Garvey, C.3
-
87
-
-
63249124498
-
Pulmonary rehabilitation for management of chronic obstructive pulmonary disease
-
Casaburi, R, ZuWallack, R, Pulmonary rehabilitation for management of chronic obstructive pulmonary disease. N Engl J Med 360 (2009), 1329–1335.
-
(2009)
N Engl J Med
, vol.360
, pp. 1329-1335
-
-
Casaburi, R.1
ZuWallack, R.2
-
88
-
-
80155184731
-
Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease
-
CD005305.
-
Puhan, MA, Gimeno-Santos, E, Scharplatz, M, Troosters, T, Walters, EH, Steurer, J, Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev, 2011 CD005305.
-
(2011)
Cochrane Database Syst Rev
-
-
Puhan, M.A.1
Gimeno-Santos, E.2
Scharplatz, M.3
Troosters, T.4
Walters, E.H.5
Steurer, J.6
-
89
-
-
84948967244
-
An Official American Thoracic Society/European Respiratory Society Policy Statement: enhancing implementation, use, and delivery of pulmonary rehabilitation
-
Rochester, CL, Vogiatzis, I, Holland, AE, et al. An Official American Thoracic Society/European Respiratory Society Policy Statement: enhancing implementation, use, and delivery of pulmonary rehabilitation. Am J Respir Crit Care Med 192 (2015), 1373–1386.
-
(2015)
Am J Respir Crit Care Med
, vol.192
, pp. 1373-1386
-
-
Rochester, C.L.1
Vogiatzis, I.2
Holland, A.E.3
-
90
-
-
79953166862
-
Tiotropium versus salmeterol for the prevention of exacerbations of COPD
-
Vogelmeier, C, Hederer, B, Glaab, T, et al. Tiotropium versus salmeterol for the prevention of exacerbations of COPD. N Engl J Med 364 (2011), 1093–1103.
-
(2011)
N Engl J Med
, vol.364
, pp. 1093-1103
-
-
Vogelmeier, C.1
Hederer, B.2
Glaab, T.3
-
91
-
-
84883461908
-
Once-daily indacaterol versus tiotropium for patients with severe chronic obstructive pulmonary disease (INVIGORATE): a randomised, blinded, parallel-group study
-
Decramer, ML, Chapman, KR, Dahl, R, et al. Once-daily indacaterol versus tiotropium for patients with severe chronic obstructive pulmonary disease (INVIGORATE): a randomised, blinded, parallel-group study. Lancet Respir Med 1 (2013), 524–533.
-
(2013)
Lancet Respir Med
, vol.1
, pp. 524-533
-
-
Decramer, M.L.1
Chapman, K.R.2
Dahl, R.3
-
92
-
-
37849011194
-
The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide
-
Wedzicha, JA, Calverley, PM, Seemungal, TA, Hagan, G, Ansari, Z, Stockley, RA, The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide. Am J Respir Crit Care Med 177 (2008), 19–26.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 19-26
-
-
Wedzicha, J.A.1
Calverley, P.M.2
Seemungal, T.A.3
Hagan, G.4
Ansari, Z.5
Stockley, R.A.6
-
93
-
-
84891372240
-
Effect of ADRB2 polymorphisms on the efficacy of salmeterol and tiotropium in preventing COPD exacerbations: a prespecified substudy of the POET-COPD trial
-
Rabe, KF, Fabbri, LM, Israel, E, et al. Effect of ADRB2 polymorphisms on the efficacy of salmeterol and tiotropium in preventing COPD exacerbations: a prespecified substudy of the POET-COPD trial. Lancet Respir Med 2 (2014), 44–53.
-
(2014)
Lancet Respir Med
, vol.2
, pp. 44-53
-
-
Rabe, K.F.1
Fabbri, L.M.2
Israel, E.3
-
94
-
-
84877131237
-
Analysis of chronic obstructive pulmonary disease exacerbations with the dual bronchodilator QVA149 compared with glycopyrronium and tiotropium (SPARK): a randomised, double-blind, parallel-group study
-
Wedzicha, JA, Decramer, M, Ficker, JH, et al. Analysis of chronic obstructive pulmonary disease exacerbations with the dual bronchodilator QVA149 compared with glycopyrronium and tiotropium (SPARK): a randomised, double-blind, parallel-group study. Lancet Respir Med 1 (2013), 199–209.
-
(2013)
Lancet Respir Med
, vol.1
, pp. 199-209
-
-
Wedzicha, J.A.1
Decramer, M.2
Ficker, J.H.3
-
95
-
-
84989195861
-
Single inhaler triple therapy versus inhaled corticosteroid plus long-acting beta2-agonist therapy for chronic obstructive pulmonary disease (TRILOGY): a double-blind, parallel group, randomised controlled trial
-
Singh, D, Papi, A, Corradi, M, et al. Single inhaler triple therapy versus inhaled corticosteroid plus long-acting beta2-agonist therapy for chronic obstructive pulmonary disease (TRILOGY): a double-blind, parallel group, randomised controlled trial. Lancet 388 (2016), 963–973.
-
(2016)
Lancet
, vol.388
, pp. 963-973
-
-
Singh, D.1
Papi, A.2
Corradi, M.3
-
96
-
-
84907779764
-
Withdrawal of inhaled glucocorticoids and exacerbations of COPD
-
Magnussen, H, Disse, B, Rodriguez-Roisin, R, et al. Withdrawal of inhaled glucocorticoids and exacerbations of COPD. N Engl J Med 371 (2014), 1285–1294.
-
(2014)
N Engl J Med
, vol.371
, pp. 1285-1294
-
-
Magnussen, H.1
Disse, B.2
Rodriguez-Roisin, R.3
-
97
-
-
84930866341
-
Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trials
-
Pascoe, S, Locantore, N, Dransfield, MT, Barnes, NC, Pavord, ID, Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trials. Lancet Respir Med 3 (2015), 435–442.
-
(2015)
Lancet Respir Med
, vol.3
, pp. 435-442
-
-
Pascoe, S.1
Locantore, N.2
Dransfield, M.T.3
Barnes, N.C.4
Pavord, I.D.5
-
98
-
-
84939433292
-
Blood Eosinophils: a biomarker of response to extrafine beclomethasone/formoterol in chronic obstructive pulmonary disease
-
Siddiqui, SH, Guasconi, A, Vestbo, J, et al. Blood Eosinophils: a biomarker of response to extrafine beclomethasone/formoterol in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 192 (2015), 523–525.
-
(2015)
Am J Respir Crit Care Med
, vol.192
, pp. 523-525
-
-
Siddiqui, S.H.1
Guasconi, A.2
Vestbo, J.3
-
99
-
-
84964388893
-
Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the WISDOM trial
-
Watz, H, Tetzlaff, K, Wouters, EF, et al. Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the WISDOM trial. Lancet Respir Med 4 (2016), 390–398.
-
(2016)
Lancet Respir Med
, vol.4
, pp. 390-398
-
-
Watz, H.1
Tetzlaff, K.2
Wouters, E.F.3
-
100
-
-
84958109521
-
Cardiac effects of current treatments of chronic obstructive pulmonary disease
-
Lahousse, L, Verhamme, KM, Stricker, BH, Brusselle, GG, Cardiac effects of current treatments of chronic obstructive pulmonary disease. Lancet Respir Med 4 (2016), 149–164.
-
(2016)
Lancet Respir Med
, vol.4
, pp. 149-164
-
-
Lahousse, L.1
Verhamme, K.M.2
Stricker, B.H.3
Brusselle, G.G.4
-
101
-
-
84870598137
-
Combined corticosteroid and long-acting beta(2)-agonist in one inhaler versus long-acting beta(2)-agonists for chronic obstructive pulmonary disease
-
CD006829.
-
Nannini, LJ, Lasserson, TJ, Poole, P, Combined corticosteroid and long-acting beta(2)-agonist in one inhaler versus long-acting beta(2)-agonists for chronic obstructive pulmonary disease. Cochrane Database Syst Rev, 2012 CD006829.
-
(2012)
Cochrane Database Syst Rev
-
-
Nannini, L.J.1
Lasserson, T.J.2
Poole, P.3
-
102
-
-
70349088498
-
Pneumonia risk in COPD patients receiving inhaled corticosteroids alone or in combination: TORCH study results
-
Crim, C, Calverley, PM, Anderson, JA, et al. Pneumonia risk in COPD patients receiving inhaled corticosteroids alone or in combination: TORCH study results. Eur Respir J 34 (2009), 641–647.
-
(2009)
Eur Respir J
, vol.34
, pp. 641-647
-
-
Crim, C.1
Calverley, P.M.2
Anderson, J.A.3
-
103
-
-
84922423567
-
Pneumonia risk with inhaled fluticasone furoate and vilanterol compared with vilanterol alone in patients with COPD
-
Crim, C, Dransfield, MT, Bourbeau, J, et al. Pneumonia risk with inhaled fluticasone furoate and vilanterol compared with vilanterol alone in patients with COPD. Ann Am Thorac Soc 12 (2015), 27–34.
-
(2015)
Ann Am Thorac Soc
, vol.12
, pp. 27-34
-
-
Crim, C.1
Dransfield, M.T.2
Bourbeau, J.3
-
104
-
-
84918840018
-
Inhaled corticosteroids and pneumonia in chronic obstructive pulmonary disease
-
Finney, L, Berry, M, Singanayagam, A, Elkin, SL, Johnston, SL, Mallia, P, Inhaled corticosteroids and pneumonia in chronic obstructive pulmonary disease. Lancet Respir Med 2 (2014), 919–932.
-
(2014)
Lancet Respir Med
, vol.2
, pp. 919-932
-
-
Finney, L.1
Berry, M.2
Singanayagam, A.3
Elkin, S.L.4
Johnston, S.L.5
Mallia, P.6
-
105
-
-
84989816140
-
Blood eosinophil count and pneumonia risk in patients with chronic obstructive pulmonary disease: a patient-level meta-analysis
-
Pavord, ID, Lettis, S, Anzueto, A, Barnes, N, Blood eosinophil count and pneumonia risk in patients with chronic obstructive pulmonary disease: a patient-level meta-analysis. Lancet Respir Med 4 (2016), 731–741.
-
(2016)
Lancet Respir Med
, vol.4
, pp. 731-741
-
-
Pavord, I.D.1
Lettis, S.2
Anzueto, A.3
Barnes, N.4
-
106
-
-
84929661059
-
Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management
-
Woodruff, PG, Agusti, A, Roche, N, Singh, D, Martinez, FJ, Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management. Lancet 385 (2015), 1789–1798.
-
(2015)
Lancet
, vol.385
, pp. 1789-1798
-
-
Woodruff, P.G.1
Agusti, A.2
Roche, N.3
Singh, D.4
Martinez, F.J.5
-
107
-
-
69149098943
-
Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials
-
Fabbri, LM, Calverley, PM, Izquierdo-Alonso, JL, et al. Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials. Lancet 374 (2009), 695–703.
-
(2009)
Lancet
, vol.374
, pp. 695-703
-
-
Fabbri, L.M.1
Calverley, P.M.2
Izquierdo-Alonso, J.L.3
-
108
-
-
84924250308
-
Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial
-
Martinez, FJ, Calverley, PM, Goehring, UM, Brose, M, Fabbri, LM, Rabe, KF, Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial. Lancet 385 (2015), 857–866.
-
(2015)
Lancet
, vol.385
, pp. 857-866
-
-
Martinez, F.J.1
Calverley, P.M.2
Goehring, U.M.3
Brose, M.4
Fabbri, L.M.5
Rabe, K.F.6
-
109
-
-
84988882477
-
Effect of roflumilast and inhaled corticosteroid/long-acting beta2-agonist on chronic obstructive pulmonary disease exacerbations (RE(2)SPOND). A randomized clinical trial
-
Martinez, FJ, Rabe, KF, Sethi, S, et al. Effect of roflumilast and inhaled corticosteroid/long-acting beta2-agonist on chronic obstructive pulmonary disease exacerbations (RE(2)SPOND). A randomized clinical trial. Am J Respir Crit Care Med 194 (2016), 559–567.
-
(2016)
Am J Respir Crit Care Med
, vol.194
, pp. 559-567
-
-
Martinez, F.J.1
Rabe, K.F.2
Sethi, S.3
-
110
-
-
80052157895
-
Azithromycin for prevention of exacerbations of COPD
-
Albert, RK, Connett, J, Bailey, WC, et al. Azithromycin for prevention of exacerbations of COPD. N Engl J Med 365 (2011), 689–698.
-
(2011)
N Engl J Med
, vol.365
, pp. 689-698
-
-
Albert, R.K.1
Connett, J.2
Bailey, W.C.3
-
111
-
-
84902665590
-
Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy
-
Han, MK, Tayob, N, Murray, S, et al. Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy. Am J Respir Crit Care Med 189 (2014), 1503–1508.
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 1503-1508
-
-
Han, M.K.1
Tayob, N.2
Murray, S.3
-
112
-
-
20944433417
-
Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial
-
Decramer, M, Rutten-van Molken, M, Dekhuijzen, PN, et al. Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial. Lancet 365 (2005), 1552–1560.
-
(2005)
Lancet
, vol.365
, pp. 1552-1560
-
-
Decramer, M.1
Rutten-van Molken, M.2
Dekhuijzen, P.N.3
-
113
-
-
84895803870
-
Twice daily N-acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomised, double-blind placebo-controlled trial
-
Zheng, JP, Wen, FQ, Bai, CX, et al. Twice daily N-acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomised, double-blind placebo-controlled trial. Lancet Respir Med 2 (2014), 187–194.
-
(2014)
Lancet Respir Med
, vol.2
, pp. 187-194
-
-
Zheng, J.P.1
Wen, F.Q.2
Bai, C.X.3
-
114
-
-
4444280869
-
Prospects for new drugs for chronic obstructive pulmonary disease
-
Barnes, PJ, Hansel, TT, Prospects for new drugs for chronic obstructive pulmonary disease. Lancet 364 (2004), 985–996.
-
(2004)
Lancet
, vol.364
, pp. 985-996
-
-
Barnes, P.J.1
Hansel, T.T.2
-
115
-
-
80052691591
-
The future of chronic obstructive pulmonary disease treatment—difficulties of and barriers to drug development
-
Martinez, FJ, Donohue, JF, Rennard, SI, The future of chronic obstructive pulmonary disease treatment—difficulties of and barriers to drug development. Lancet 378 (2011), 1027–1037.
-
(2011)
Lancet
, vol.378
, pp. 1027-1037
-
-
Martinez, F.J.1
Donohue, J.F.2
Rennard, S.I.3
-
116
-
-
84891373802
-
Efficacy and safety of the p38 MAPK inhibitor losmapimod for patients with chronic obstructive pulmonary disease: a randomised, double-blind, placebo-controlled trial
-
Watz, H, Barnacle, H, Hartley, BF, Chan, R, Efficacy and safety of the p38 MAPK inhibitor losmapimod for patients with chronic obstructive pulmonary disease: a randomised, double-blind, placebo-controlled trial. Lancet Respir Med 2 (2014), 63–72.
-
(2014)
Lancet Respir Med
, vol.2
, pp. 63-72
-
-
Watz, H.1
Barnacle, H.2
Hartley, B.F.3
Chan, R.4
-
117
-
-
84918798923
-
Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study
-
Brightling, CE, Bleecker, ER, Panettieri, RA Jr, et al. Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study. Lancet Respir Med 2 (2014), 891–901.
-
(2014)
Lancet Respir Med
, vol.2
, pp. 891-901
-
-
Brightling, C.E.1
Bleecker, E.R.2
Panettieri, R.A.3
-
118
-
-
84928985245
-
CXCR2 antagonist MK-7123. A phase 2 proof-of-concept trial for chronic obstructive pulmonary disease
-
Rennard, SI, Dale, DC, Donohue, JF, et al. CXCR2 antagonist MK-7123. A phase 2 proof-of-concept trial for chronic obstructive pulmonary disease. Am J Respir Crit Care Med 191 (2015), 1001–1011.
-
(2015)
Am J Respir Crit Care Med
, vol.191
, pp. 1001-1011
-
-
Rennard, S.I.1
Dale, D.C.2
Donohue, J.F.3
-
119
-
-
84887115924
-
Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials
-
Franciosi, LG, Diamant, Z, Banner, KH, et al. Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials. Lancet Respir Med 1 (2013), 714–727.
-
(2013)
Lancet Respir Med
, vol.1
, pp. 714-727
-
-
Franciosi, L.G.1
Diamant, Z.2
Banner, K.H.3
-
120
-
-
84882569009
-
Safety and tolerability of the inhaled phosphodiesterase 4 inhibitor GSK256066 in moderate COPD
-
Watz, H, Mistry, SJ, Lazaar, AL, Safety and tolerability of the inhaled phosphodiesterase 4 inhibitor GSK256066 in moderate COPD. Pulm Pharmacol Ther 26 (2013), 588–595.
-
(2013)
Pulm Pharmacol Ther
, vol.26
, pp. 588-595
-
-
Watz, H.1
Mistry, S.J.2
Lazaar, A.L.3
-
121
-
-
85008975685
-
Lung volume reduction for emphysema
-
Shah, PL, Herth, FJ, van Geffen, WH, Deslee, G, Slebos, DJ, Lung volume reduction for emphysema. Lancet Respir Med 5 (2016), 147–156.
-
(2016)
Lancet Respir Med
, vol.5
, pp. 147-156
-
-
Shah, P.L.1
Herth, F.J.2
van Geffen, W.H.3
Deslee, G.4
Slebos, D.J.5
-
122
-
-
84959196483
-
Endoscopic lung volume reduction: an expert panel recommendation
-
Herth, FJ, Slebos, DJ, Rabe, KF, Shah, PL, Endoscopic lung volume reduction: an expert panel recommendation. Respiration 91 (2016), 241–250.
-
(2016)
Respiration
, vol.91
, pp. 241-250
-
-
Herth, F.J.1
Slebos, D.J.2
Rabe, K.F.3
Shah, P.L.4
-
123
-
-
84969919957
-
Effect of endobronchial coils vs usual care on exercise tolerance in patients with severe emphysema: the RENEW randomized clinical trial
-
Sciurba, FC, Criner, GJ, Strange, C, et al. Effect of endobronchial coils vs usual care on exercise tolerance in patients with severe emphysema: the RENEW randomized clinical trial. JAMA 315 (2016), 2178–2189.
-
(2016)
JAMA
, vol.315
, pp. 2178-2189
-
-
Sciurba, F.C.1
Criner, G.J.2
Strange, C.3
-
124
-
-
77957127502
-
A randomized study of endobronchial valves for advanced emphysema
-
Sciurba, FC, Ernst, A, Herth, FJ, et al. A randomized study of endobronchial valves for advanced emphysema. N Engl J Med 363 (2010), 1233–1244.
-
(2010)
N Engl J Med
, vol.363
, pp. 1233-1244
-
-
Sciurba, F.C.1
Ernst, A.2
Herth, F.J.3
-
125
-
-
84959490742
-
Segmental volume reduction using thermal vapour ablation in patients with severe emphysema: 6-month results of the multicentre, parallel-group, open-label, randomised controlled STEP-UP trial
-
Herth, FJ, Valipour, A, Shah, PL, et al. Segmental volume reduction using thermal vapour ablation in patients with severe emphysema: 6-month results of the multicentre, parallel-group, open-label, randomised controlled STEP-UP trial. Lancet Respir Med 4 (2016), 185–193.
-
(2016)
Lancet Respir Med
, vol.4
, pp. 185-193
-
-
Herth, F.J.1
Valipour, A.2
Shah, P.L.3
-
126
-
-
80052728433
-
Bronchoscopic lung-volume reduction with Exhale airway stents for emphysema (EASE trial): randomised, sham-controlled, multicentre trial
-
Shah, PL, Slebos, DJ, Cardoso, PF, et al. Bronchoscopic lung-volume reduction with Exhale airway stents for emphysema (EASE trial): randomised, sham-controlled, multicentre trial. Lancet 378 (2011), 997–1005.
-
(2011)
Lancet
, vol.378
, pp. 997-1005
-
-
Shah, P.L.1
Slebos, D.J.2
Cardoso, P.F.3
-
127
-
-
84992740402
-
A randomized trial of long-term oxygen for COPD with moderate desaturation
-
The Long-Term Oxygen Treatment Trial Research Group. A randomized trial of long-term oxygen for COPD with moderate desaturation. N Engl J Med 375 (2016), 1617–1627.
-
(2016)
N Engl J Med
, vol.375
, pp. 1617-1627
-
-
-
128
-
-
84992730272
-
Clinical usefulness of long-term oxygen therapy in adults
-
Ekstrom, M, Clinical usefulness of long-term oxygen therapy in adults. N Engl J Med 375 (2016), 1683–1684.
-
(2016)
N Engl J Med
, vol.375
, pp. 1683-1684
-
-
Ekstrom, M.1
-
129
-
-
84908047257
-
Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled clinical trial
-
Kohnlein, T, Windisch, W, Kohler, D, et al. Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled clinical trial. Lancet Respir Med 2 (2014), 698–705.
-
(2014)
Lancet Respir Med
, vol.2
, pp. 698-705
-
-
Kohnlein, T.1
Windisch, W.2
Kohler, D.3
-
130
-
-
84968779698
-
Fluticasone furoate and vilanterol and survival in chronic obstructive pulmonary disease with heightened cardiovascular risk (SUMMIT): a double-blind randomised controlled trial
-
Vestbo, J, Anderson, JA, Brook, RD, et al. Fluticasone furoate and vilanterol and survival in chronic obstructive pulmonary disease with heightened cardiovascular risk (SUMMIT): a double-blind randomised controlled trial. Lancet 387 (2016), 1817–1826.
-
(2016)
Lancet
, vol.387
, pp. 1817-1826
-
-
Vestbo, J.1
Anderson, J.A.2
Brook, R.D.3
-
131
-
-
84981298126
-
Lung deflation and cardiovascular structure and function in chronic obstructive pulmonary disease. A randomized controlled trial
-
Stone, IS, Barnes, NC, James, WY, et al. Lung deflation and cardiovascular structure and function in chronic obstructive pulmonary disease. A randomized controlled trial. Am J Respir Crit Care Med 193 (2016), 717–726.
-
(2016)
Am J Respir Crit Care Med
, vol.193
, pp. 717-726
-
-
Stone, I.S.1
Barnes, N.C.2
James, W.Y.3
-
132
-
-
84884305030
-
Cardiovascular safety in patients receiving roflumilast for the treatment of COPD
-
White, WB, Cooke, GE, Kowey, PR, et al. Cardiovascular safety in patients receiving roflumilast for the treatment of COPD. Chest 144 (2013), 758–765.
-
(2013)
Chest
, vol.144
, pp. 758-765
-
-
White, W.B.1
Cooke, G.E.2
Kowey, P.R.3
-
133
-
-
84866148535
-
Effect of the phosphodiesterase 4 inhibitor roflumilast on glucose metabolism in patients with treatment-naive, newly diagnosed type 2 diabetes mellitus
-
Wouters, EF, Bredenbroker, D, Teichmann, P, et al. Effect of the phosphodiesterase 4 inhibitor roflumilast on glucose metabolism in patients with treatment-naive, newly diagnosed type 2 diabetes mellitus. J Clin Endocrinol Metab 97 (2012), E1720–E1725.
-
(2012)
J Clin Endocrinol Metab
, vol.97
, pp. E1720-E1725
-
-
Wouters, E.F.1
Bredenbroker, D.2
Teichmann, P.3
-
134
-
-
85009729276
-
New therapies for asthma and chronic obstructive pulmonary disease
-
Gross, NJ, Barnes, PJ, New therapies for asthma and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 195 (2017), 159–166.
-
(2017)
Am J Respir Crit Care Med
, vol.195
, pp. 159-166
-
-
Gross, N.J.1
Barnes, P.J.2
-
135
-
-
34548290964
-
COPD exacerbations: defining their cause and prevention
-
Wedzicha, JA, Seemungal, TA, COPD exacerbations: defining their cause and prevention. Lancet 370 (2007), 786–796.
-
(2007)
Lancet
, vol.370
, pp. 786-796
-
-
Wedzicha, J.A.1
Seemungal, T.A.2
-
136
-
-
84954220438
-
Risk of death and readmission of hospital-admitted COPD exacerbations: European COPD Audit
-
Hartl, S, Lopez-Campos, JL, Pozo-Rodriguez, F, et al. Risk of death and readmission of hospital-admitted COPD exacerbations: European COPD Audit. Eur Respir J 47 (2016), 113–121.
-
(2016)
Eur Respir J
, vol.47
, pp. 113-121
-
-
Hartl, S.1
Lopez-Campos, J.L.2
Pozo-Rodriguez, F.3
-
137
-
-
84878538257
-
Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial
-
Leuppi, JD, Schuetz, P, Bingisser, R, et al. Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial. JAMA 309 (2013), 2223–2231.
-
(2013)
JAMA
, vol.309
, pp. 2223-2231
-
-
Leuppi, J.D.1
Schuetz, P.2
Bingisser, R.3
-
138
-
-
84928813719
-
Randomized double blind placebo-controlled study to demonstrate that antibiotics are not needed in moderate acute exacerbations of COPD—the ABACOPD study
-
Rohde, GG, Koch, A, Welte, T, Randomized double blind placebo-controlled study to demonstrate that antibiotics are not needed in moderate acute exacerbations of COPD—the ABACOPD study. BMC Pulm Med, 15, 2015, 5.
-
(2015)
BMC Pulm Med
, vol.15
, pp. 5
-
-
Rohde, G.G.1
Koch, A.2
Welte, T.3
-
139
-
-
84958121472
-
Cardiac dysfunction during exacerbations of chronic obstructive pulmonary disease
-
MacDonald, MI, Shafuddin, E, King, PT, Chang, CL, Bardin, PG, Hancox, RJ, Cardiac dysfunction during exacerbations of chronic obstructive pulmonary disease. Lancet Respir Med 4 (2016), 138–148.
-
(2016)
Lancet Respir Med
, vol.4
, pp. 138-148
-
-
MacDonald, M.I.1
Shafuddin, E.2
King, P.T.3
Chang, C.L.4
Bardin, P.G.5
Hancox, R.J.6
-
140
-
-
85029471738
-
Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline
-
Wedzicha, JA, Miravitlles, M, Hurst, JR, et al. Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline. Eur Respir J, 49, 2017, 1600791.
-
(2017)
Eur Respir J
, vol.49
, pp. 1600791
-
-
Wedzicha, J.A.1
Miravitlles, M.2
Hurst, J.R.3
-
141
-
-
84868209480
-
Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality
-
Suissa, S, Dell'Aniello, S, Ernst, P, Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality. Thorax 67 (2012), 957–963.
-
(2012)
Thorax
, vol.67
, pp. 957-963
-
-
Suissa, S.1
Dell'Aniello, S.2
Ernst, P.3
|