-
2
-
-
84920625804
-
Early-life risk factors for chronic nonrespiratory diseases
-
Chacko A, Carpenter DO, Callaway L, Sly PD Early-life risk factors for chronic nonrespiratory diseases. Eur Respir J 2015, 45:244-259.
-
(2015)
Eur Respir J
, vol.45
, pp. 244-259
-
-
Chacko, A.1
Carpenter, D.O.2
Callaway, L.3
Sly, P.D.4
-
3
-
-
56249083570
-
Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD
-
Mannino DM, Thorn D, Swensen A, Holguin F Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD. Eur Respir J 2008, 32:962-969.
-
(2008)
Eur Respir J
, vol.32
, pp. 962-969
-
-
Mannino, D.M.1
Thorn, D.2
Swensen, A.3
Holguin, F.4
-
4
-
-
84947045603
-
Chronic obstructive pulmonary disease and cerebrovascular disease: A comprehensive review
-
Lahousse L, Tiemeier H, Ikram MA, Brusselle GG Chronic obstructive pulmonary disease and cerebrovascular disease: A comprehensive review. Respir Med 2015, 109:1371-1380.
-
(2015)
Respir Med
, vol.109
, pp. 1371-1380
-
-
Lahousse, L.1
Tiemeier, H.2
Ikram, M.A.3
Brusselle, G.G.4
-
5
-
-
84863952703
-
Comorbidities and risk of mortality in patients with chronic obstructive pulmonary disease
-
the BODE Collaborative Group
-
Divo M, Cote C, de Torres JP, et al. Comorbidities and risk of mortality in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2012, 186:155-161. the BODE Collaborative Group.
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 155-161
-
-
Divo, M.1
Cote, C.2
de Torres, J.P.3
-
6
-
-
33845361633
-
Mortality in COPD: Role of comorbidities
-
Sin DD, Anthonisen NR, Soriano JB, Agusti AG Mortality in COPD: Role of comorbidities. Eur Respir J 2006, 28:1245-1257.
-
(2006)
Eur Respir J
, vol.28
, pp. 1245-1257
-
-
Sin, D.D.1
Anthonisen, N.R.2
Soriano, J.B.3
Agusti, A.G.4
-
7
-
-
78149361805
-
Prevalence of major comorbidities in subjects with COPD and incidence of myocardial infarction and stroke: a comprehensive analysis using data from primary care
-
Feary JR, Rodrigues LC, Smith CJ, Hubbard RB, Gibson JE Prevalence of major comorbidities in subjects with COPD and incidence of myocardial infarction and stroke: a comprehensive analysis using data from primary care. Thorax 2010, 65:956-962.
-
(2010)
Thorax
, vol.65
, pp. 956-962
-
-
Feary, J.R.1
Rodrigues, L.C.2
Smith, C.J.3
Hubbard, R.B.4
Gibson, J.E.5
-
8
-
-
68849111117
-
A postmortem analysis of major causes of early death in patients hospitalized with COPD exacerbation
-
Zvezdin B, Milutinov S, Kojicic M, et al. A postmortem analysis of major causes of early death in patients hospitalized with COPD exacerbation. Chest 2009, 136:376-380.
-
(2009)
Chest
, vol.136
, pp. 376-380
-
-
Zvezdin, B.1
Milutinov, S.2
Kojicic, M.3
-
9
-
-
27144461153
-
COPD and incident cardiovascular disease hospitalizations and mortality: Kaiser Permanente Medical Care Program
-
Sidney S, Sorel M, Quesenberry CP, DeLuise C, Lanes S, Eisner MD COPD and incident cardiovascular disease hospitalizations and mortality: Kaiser Permanente Medical Care Program. Chest 2005, 128:2068-2075.
-
(2005)
Chest
, vol.128
, pp. 2068-2075
-
-
Sidney, S.1
Sorel, M.2
Quesenberry, C.P.3
DeLuise, C.4
Lanes, S.5
Eisner, M.D.6
-
10
-
-
84938343502
-
Chronic obstructive pulmonary disease and sudden cardiac death: the Rotterdam study
-
Lahousse L, Niemeijer MN, van den Berg ME, et al. Chronic obstructive pulmonary disease and sudden cardiac death: the Rotterdam study. Eur Heart J 2015, 36:1754-1761.
-
(2015)
Eur Heart J
, vol.36
, pp. 1754-1761
-
-
Lahousse, L.1
Niemeijer, M.N.2
van den Berg, M.E.3
-
11
-
-
84873956600
-
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
-
Vestbo J, Hurd SS, Agustí AG, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2013, 187:347-365.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 347-365
-
-
Vestbo, J.1
Hurd, S.S.2
Agustí, A.G.3
-
12
-
-
84863426446
-
Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study
-
Barnett K, Mercer SW, Norbury M, Watt G, Wyke S, Guthrie B Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study. Lancet 2012, 380:37-43.
-
(2012)
Lancet
, vol.380
, pp. 37-43
-
-
Barnett, K.1
Mercer, S.W.2
Norbury, M.3
Watt, G.4
Wyke, S.5
Guthrie, B.6
-
13
-
-
34447120838
-
Reducing cholinergic constriction: the major reversible mechanism in COPD
-
Brusasco V Reducing cholinergic constriction: the major reversible mechanism in COPD. Eur Respir Rev 2006, 195:32-36.
-
(2006)
Eur Respir Rev
, vol.195
, pp. 32-36
-
-
Brusasco, V.1
-
14
-
-
53749102775
-
A 4-year trial of tiotropium in chronic obstructive pulmonary disease
-
the UPLIFT Study Investigators
-
Tashkin DP, Celli B, Senn S, et al. A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N Engl J Med 2008, 359:1543-1554. the UPLIFT Study Investigators.
-
(2008)
N Engl J Med
, vol.359
, pp. 1543-1554
-
-
Tashkin, D.P.1
Celli, B.2
Senn, S.3
-
15
-
-
72849144086
-
Mortality in the 4-year trial of tiotropium (UPLIFT) in patients with chronic obstructive pulmonary disease
-
the UPLIFT Study Investigators
-
Celli B, Decramer M, Kesten S, Liu D, Mehra S, Tashkin DP Mortality in the 4-year trial of tiotropium (UPLIFT) in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2009, 180:948-955. the UPLIFT Study Investigators.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 948-955
-
-
Celli, B.1
Decramer, M.2
Kesten, S.3
Liu, D.4
Mehra, S.5
Tashkin, D.P.6
-
16
-
-
52449106502
-
Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
-
Singh S, Loke YK, Furberg CD Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis. JAMA 2008, 300:1439-1450.
-
(2008)
JAMA
, vol.300
, pp. 1439-1450
-
-
Singh, S.1
Loke, Y.K.2
Furberg, C.D.3
-
17
-
-
77956712835
-
The safety of tiotropium-the FDA's conclusions
-
Michele TM, Pinheiro S, Iyasu S The safety of tiotropium-the FDA's conclusions. N Engl J Med 2010, 363:1097-1099.
-
(2010)
N Engl J Med
, vol.363
, pp. 1097-1099
-
-
Michele, T.M.1
Pinheiro, S.2
Iyasu, S.3
-
18
-
-
0027962628
-
Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study
-
Anthonisen NR, Connett JE, Kiley JP, et al. Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study. JAMA 1994, 272:1497-1505.
-
(1994)
JAMA
, vol.272
, pp. 1497-1505
-
-
Anthonisen, N.R.1
Connett, J.E.2
Kiley, J.P.3
-
19
-
-
0036683267
-
Hospitalizations and mortality in the Lung Health Study
-
the Lung Health Study Research Group
-
Anthonisen NR, Connett JE, Enright PL, Manfreda J Hospitalizations and mortality in the Lung Health Study. Am J Respir Crit Care Med 2002, 166:333-339. the Lung Health Study Research Group.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 333-339
-
-
Anthonisen, N.R.1
Connett, J.E.2
Enright, P.L.3
Manfreda, J.4
-
20
-
-
84922643059
-
Tiotropium handihaler and respimat in COPD: a pooled safety analysis
-
Halpin DMG, Dahl R, Hallmann C, Mueller A, Tashkin D Tiotropium handihaler and respimat in COPD: a pooled safety analysis. Int J Chron Obstruct Pulmon Dis 2015, 10:239-259.
-
(2015)
Int J Chron Obstruct Pulmon Dis
, vol.10
, pp. 239-259
-
-
Halpin, D.M.G.1
Dahl, R.2
Hallmann, C.3
Mueller, A.4
Tashkin, D.5
-
21
-
-
84871396857
-
Comparative safety of inhaled medications in patients with chronic obstructive pulmonary disease: systematic review and mixed treatment comparison meta-analysis of randomised controlled trials
-
Dong Y-H, Lin H-H, Shau W-Y, Wu Y-C, Chang C-H, Lai M-Comparative safety of inhaled medications in patients with chronic obstructive pulmonary disease: systematic review and mixed treatment comparison meta-analysis of randomised controlled trials. Thorax 2013, 68:48-56.
-
(2013)
Thorax
, vol.68
, pp. 48-56
-
-
Dong, Y.-H.1
Lin, H.-H.2
Shau, W.-Y.3
Wu, Y.-C.4
Chang, C.-H.5
Lai, M.-S.6
-
22
-
-
84883495199
-
Use of tiotropium Respimat Soft Mist Inhaler versus HandiHaler and mortality in patients with COPD
-
Verhamme KMC, Afonso A, Romio S, Stricker BC, Brusselle GGO, Sturkenboom MCJM Use of tiotropium Respimat Soft Mist Inhaler versus HandiHaler and mortality in patients with COPD. Eur Respir J 2013, 42:606-615.
-
(2013)
Eur Respir J
, vol.42
, pp. 606-615
-
-
Verhamme, K.M.C.1
Afonso, A.2
Romio, S.3
Stricker, B.C.4
Brusselle, G.G.O.5
Sturkenboom, M.C.J.M.6
-
23
-
-
84885734407
-
Tiotropium Respimat inhaler and the risk of death in COPD
-
the TIOSPIR Investigators
-
Wise RA, Anzueto A, Cotton D, et al. Tiotropium Respimat inhaler and the risk of death in COPD. N Engl J Med 2013, 369:1491-1501. the TIOSPIR Investigators.
-
(2013)
N Engl J Med
, vol.369
, pp. 1491-1501
-
-
Wise, R.A.1
Anzueto, A.2
Cotton, D.3
-
24
-
-
84939233935
-
Safety of inhaled glycopyrronium in patients with COPD: a comprehensive analysis of clinical studies and post-marketing data
-
D'Urzo AD, Kerwin EM, Chapman KR, et al. Safety of inhaled glycopyrronium in patients with COPD: a comprehensive analysis of clinical studies and post-marketing data. Int J Chron Obstruct Pulmon Dis 2015, 10:1599-1612.
-
(2015)
Int J Chron Obstruct Pulmon Dis
, vol.10
, pp. 1599-1612
-
-
D'Urzo, A.D.1
Kerwin, E.M.2
Chapman, K.R.3
-
25
-
-
84891919272
-
Umeclidinium in patients with COPD: a randomised, placebo-controlled study
-
Trivedi R, Richard N, Mehta R, Church A Umeclidinium in patients with COPD: a randomised, placebo-controlled study. Eur Respir J 2014, 43:72-81.
-
(2014)
Eur Respir J
, vol.43
, pp. 72-81
-
-
Trivedi, R.1
Richard, N.2
Mehta, R.3
Church, A.4
-
26
-
-
84885766455
-
Inhaled corticosteroids in COPD and the risk of serious pneumonia
-
Suissa S, Patenaude V, Lapi F, Ernst P Inhaled corticosteroids in COPD and the risk of serious pneumonia. Thorax 2013, 68:1029-1036.
-
(2013)
Thorax
, vol.68
, pp. 1029-1036
-
-
Suissa, S.1
Patenaude, V.2
Lapi, F.3
Ernst, P.4
-
27
-
-
84930872686
-
Targeted therapy with inhaled corticosteroids in COPD according to blood eosinophil counts
-
Brusselle GG, Bracke K, Lahousse L Targeted therapy with inhaled corticosteroids in COPD according to blood eosinophil counts. Lancet Respir Med 2015, 3:416-417.
-
(2015)
Lancet Respir Med
, vol.3
, pp. 416-417
-
-
Brusselle, G.G.1
Bracke, K.2
Lahousse, L.3
-
28
-
-
84873342637
-
The safety of long-acting β2-agonists in the treatment of stable chronic obstructive pulmonary disease
-
Decramer ML, Hanania NA, Lötvall JO, Yawn BP The safety of long-acting β2-agonists in the treatment of stable chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 2013, 8:53-64.
-
(2013)
Int J Chron Obstruct Pulmon Dis
, vol.8
, pp. 53-64
-
-
Decramer, M.L.1
Hanania, N.A.2
Lötvall, J.O.3
Yawn, B.P.4
-
29
-
-
79953658881
-
2-agonists, alone or in combination with inhaled corticosteroids, in chronic obstructive pulmonary disease (COPD): a risk-benefit analysis
-
2-agonists, alone or in combination with inhaled corticosteroids, in chronic obstructive pulmonary disease (COPD): a risk-benefit analysis. Pharmacol Ther 2011, 130:114-143.
-
(2011)
Pharmacol Ther
, vol.130
, pp. 114-143
-
-
Cave, A.C.1
Hurst, M.M.2
-
30
-
-
84864806557
-
Bronchodilator use and the risk of arrhythmia in COPD: part 1: Saskatchewan cohort study
-
Wilchesky M, Ernst P, Brophy JM, Platt RW, Suissa S Bronchodilator use and the risk of arrhythmia in COPD: part 1: Saskatchewan cohort study. Chest 2012, 142:298-304.
-
(2012)
Chest
, vol.142
, pp. 298-304
-
-
Wilchesky, M.1
Ernst, P.2
Brophy, J.M.3
Platt, R.W.4
Suissa, S.5
-
31
-
-
84864805183
-
Bronchodilator use and the risk of arrhythmia in COPD: part 2: reassessment in the larger Quebec cohort
-
Wilchesky M, Ernst P, Brophy JM, Platt RW, Suissa S Bronchodilator use and the risk of arrhythmia in COPD: part 2: reassessment in the larger Quebec cohort. Chest 2012, 142:305-311.
-
(2012)
Chest
, vol.142
, pp. 305-311
-
-
Wilchesky, M.1
Ernst, P.2
Brophy, J.M.3
Platt, R.W.4
Suissa, S.5
-
32
-
-
84879999170
-
Cardiovascular safety of inhaled long-acting bronchodilators in individuals with chronic obstructive pulmonary disease
-
Gershon A, Croxford R, Calzavara A, et al. Cardiovascular safety of inhaled long-acting bronchodilators in individuals with chronic obstructive pulmonary disease. JAMA Intern Med 2013, 173:1175-1185.
-
(2013)
JAMA Intern Med
, vol.173
, pp. 1175-1185
-
-
Gershon, A.1
Croxford, R.2
Calzavara, A.3
-
33
-
-
0035672636
-
Asthma medications and their potential adverse effects in the elderly: recommendations for prescribing
-
Newnham DM Asthma medications and their potential adverse effects in the elderly: recommendations for prescribing. Drug Saf 2001, 24:1065-1080.
-
(2001)
Drug Saf
, vol.24
, pp. 1065-1080
-
-
Newnham, D.M.1
-
34
-
-
84884895703
-
Heart failure and chronic obstructive pulmonary disease: the challenges facing physicians and health services
-
Hawkins NM, Virani S, Ceconi C Heart failure and chronic obstructive pulmonary disease: the challenges facing physicians and health services. Eur Heart J 2013, 34:2795-2803.
-
(2013)
Eur Heart J
, vol.34
, pp. 2795-2803
-
-
Hawkins, N.M.1
Virani, S.2
Ceconi, C.3
-
35
-
-
0022980843
-
Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure
-
Bristow MR, Ginsburg R, Umans V, et al. Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure. Circ Res 1986, 59:297-309.
-
(1986)
Circ Res
, vol.59
, pp. 297-309
-
-
Bristow, M.R.1
Ginsburg, R.2
Umans, V.3
-
36
-
-
0034108346
-
The risk of myocardial infarction associated with inhaled beta-adrenoceptor agonists
-
Au DH, Lemaitre RN, Curtis JR, Smith NL, Psaty BM The risk of myocardial infarction associated with inhaled beta-adrenoceptor agonists. Am J Respir Crit Care Med 2000, 161:827-830.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 827-830
-
-
Au, D.H.1
Lemaitre, R.N.2
Curtis, J.R.3
Smith, N.L.4
Psaty, B.M.5
-
37
-
-
0038467503
-
Risk of mortality and heart failure exacerbations associated with inhaled beta-adrenoceptor agonists among patients with known left ventricular systolic dysfunction
-
Au DH, Udris EM, Fan VS, Curtis JR, McDonell MB, Fihn SD Risk of mortality and heart failure exacerbations associated with inhaled beta-adrenoceptor agonists among patients with known left ventricular systolic dysfunction. Chest 2003, 123:1964-1969.
-
(2003)
Chest
, vol.123
, pp. 1964-1969
-
-
Au, D.H.1
Udris, E.M.2
Fan, V.S.3
Curtis, J.R.4
McDonell, M.B.5
Fihn, S.D.6
-
38
-
-
16644394652
-
Association between chronic heart failure and inhaled beta-2-adrenoceptor agonists
-
the ACQUIP Investigators
-
Au DH, Udris EM, Curtis JR, McDonell MB, Fihn SD Association between chronic heart failure and inhaled beta-2-adrenoceptor agonists. Am Heart J 2004, 148:915-920. the ACQUIP Investigators.
-
(2004)
Am Heart J
, vol.148
, pp. 915-920
-
-
Au, D.H.1
Udris, E.M.2
Curtis, J.R.3
McDonell, M.B.4
Fihn, S.D.5
-
39
-
-
42149094428
-
Cardiovascular morbidity and the use of inhaled bronchodilators
-
Macie C, Wooldrage K, Manfreda J, Anthonisen N Cardiovascular morbidity and the use of inhaled bronchodilators. Int J Chron Obstruct Pulmon Dis 2008, 3:163-169.
-
(2008)
Int J Chron Obstruct Pulmon Dis
, vol.3
, pp. 163-169
-
-
Macie, C.1
Wooldrage, K.2
Manfreda, J.3
Anthonisen, N.4
-
40
-
-
84875818494
-
β2-agonist therapy in lung disease
-
Cazzola M, Page CP, Rogliani P, Matera MG β2-agonist therapy in lung disease. Am J Respir Crit Care Med 2013, 187:690-696.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 690-696
-
-
Cazzola, M.1
Page, C.P.2
Rogliani, P.3
Matera, M.G.4
-
41
-
-
0037092554
-
Beta-agonist intrinsic efficacy: measurement and clinical significance
-
Hanania NA, Sharafkhaneh A, Barber R, Dickey BF Beta-agonist intrinsic efficacy: measurement and clinical significance. Am J Respir Crit Care Med 2002, 165:1353-1358.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 1353-1358
-
-
Hanania, N.A.1
Sharafkhaneh, A.2
Barber, R.3
Dickey, B.F.4
-
42
-
-
33846961131
-
Some cardiac effects during short-acting and long-acting (beta)2-agonist therapy in COPD subjects
-
Gullotti D, Avila D, Lo Genco A, et al. Some cardiac effects during short-acting and long-acting (beta)2-agonist therapy in COPD subjects. Acta Med Mediterr 2006, 22:71-75.
-
(2006)
Acta Med Mediterr
, vol.22
, pp. 71-75
-
-
Gullotti, D.1
Avila, D.2
Lo Genco, A.3
-
43
-
-
0029863121
-
Salmeterol: a study by prescription-event monitoring in a UK cohort of 15,407 patients
-
Mann RD, Kubota K, Pearce G, Wilton L Salmeterol: a study by prescription-event monitoring in a UK cohort of 15,407 patients. J Clin Epidemiol 1996, 49:247-250.
-
(1996)
J Clin Epidemiol
, vol.49
, pp. 247-250
-
-
Mann, R.D.1
Kubota, K.2
Pearce, G.3
Wilton, L.4
-
44
-
-
33847172367
-
Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease
-
the TORCH investigators
-
Calverley PMA, Anderson JA, Celli B, et al. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med 2007, 356:775-789. the TORCH investigators.
-
(2007)
N Engl J Med
, vol.356
, pp. 775-789
-
-
Calverley, P.M.A.1
Anderson, J.A.2
Celli, B.3
-
45
-
-
84901372129
-
Safety and effectiveness of salmeterol xinafoate/fluticasone propionate combination inhaler (Adoair 250 Diskus) in patients with chronic obstructive pulmonary disease: final report of long-term special drug use investigation
-
Minami J, Hara T, Kobayashi A, Yoshida P Safety and effectiveness of salmeterol xinafoate/fluticasone propionate combination inhaler (Adoair 250 Diskus) in patients with chronic obstructive pulmonary disease: final report of long-term special drug use investigation. Ther Res 2014, 35:433-447.
-
(2014)
Ther Res
, vol.35
, pp. 433-447
-
-
Minami, J.1
Hara, T.2
Kobayashi, A.3
Yoshida, P.4
-
46
-
-
77956052751
-
Cardiovascular events in patients with COPD: TORCH study results
-
the TORCH Investigators
-
Calverley PMA, Anderson JA, Celli B, et al. Cardiovascular events in patients with COPD: TORCH study results. Thorax 2010, 65:719-725. the TORCH Investigators.
-
(2010)
Thorax
, vol.65
, pp. 719-725
-
-
Calverley, P.M.A.1
Anderson, J.A.2
Celli, B.3
-
48
-
-
0031810916
-
Cardiac effects of formoterol and salmeterol in patients suffering from COPD with preexisting cardiac arrhythmias and hypoxemia
-
Cazzola M, Imperatore F, Salzillo A, et al. Cardiac effects of formoterol and salmeterol in patients suffering from COPD with preexisting cardiac arrhythmias and hypoxemia. Chest 1998, 114:411-415.
-
(1998)
Chest
, vol.114
, pp. 411-415
-
-
Cazzola, M.1
Imperatore, F.2
Salzillo, A.3
-
49
-
-
84923372145
-
One-year safety and efficacy study of arformoterol tartrate in patients with moderate to severe COPD
-
Donohue JF, Hanania NA, Make B, et al. One-year safety and efficacy study of arformoterol tartrate in patients with moderate to severe COPD. Chest 2014, 146:1531-1542.
-
(2014)
Chest
, vol.146
, pp. 1531-1542
-
-
Donohue, J.F.1
Hanania, N.A.2
Make, B.3
-
50
-
-
64949164160
-
Efficacy and tolerability of budesonide/formoterol in one hydrofluoroalkane pressurized metered-dose inhaler in patients with chronic obstructive pulmonary disease: results from a 1-year randomized controlled clinical trial
-
Rennard SI, Tashkin DP, McElhattan J, et al. Efficacy and tolerability of budesonide/formoterol in one hydrofluoroalkane pressurized metered-dose inhaler in patients with chronic obstructive pulmonary disease: results from a 1-year randomized controlled clinical trial. Drugs 2009, 69:549-565.
-
(2009)
Drugs
, vol.69
, pp. 549-565
-
-
Rennard, S.I.1
Tashkin, D.P.2
McElhattan, J.3
-
51
-
-
51449109607
-
Efficacy and safety of budesonide and formoterol in one pressurized metered-dose inhaler in patients with moderate to very severe chronic obstructive pulmonary disease: results of a 6-month randomized clinical trial
-
Tashkin DP, Rennard SI, Martin P, et al. Efficacy and safety of budesonide and formoterol in one pressurized metered-dose inhaler in patients with moderate to very severe chronic obstructive pulmonary disease: results of a 6-month randomized clinical trial. Drugs 2008, 68:1975-2000.
-
(2008)
Drugs
, vol.68
, pp. 1975-2000
-
-
Tashkin, D.P.1
Rennard, S.I.2
Martin, P.3
-
52
-
-
0347473812
-
Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease
-
Calverley PM, Boonsawat W, Cseke Z, Zhong N, Peterson S, Olsson H Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease. Eur Respir J 2003, 22:912-919.
-
(2003)
Eur Respir J
, vol.22
, pp. 912-919
-
-
Calverley, P.M.1
Boonsawat, W.2
Cseke, Z.3
Zhong, N.4
Peterson, S.5
Olsson, H.6
-
53
-
-
84877088995
-
The Study to Understand Mortality and Morbidity in COPD (SUMMIT) study protocol
-
Vestbo J, Anderson J, Brook RD, et al. The Study to Understand Mortality and Morbidity in COPD (SUMMIT) study protocol. Eur Respir J 2013, 41:1017-1022.
-
(2013)
Eur Respir J
, vol.41
, pp. 1017-1022
-
-
Vestbo, J.1
Anderson, J.2
Brook, R.D.3
-
55
-
-
84958166671
-
Efficacy and safety of long-acting β-agonist/long-acting muscarinic antagonist combinations in COPD: a network meta-analysis
-
published online Oct 21.
-
Oba Y, Sarva ST, Dias S Efficacy and safety of long-acting β-agonist/long-acting muscarinic antagonist combinations in COPD: a network meta-analysis. Thorax 2015, published online Oct 21. 10.1136/thoraxjnl-2014-206732.
-
(2015)
Thorax
-
-
Oba, Y.1
Sarva, S.T.2
Dias, S.3
-
56
-
-
84908339443
-
Pooled safety analysis of the fixed-dose combination of indacaterol and glycopyrronium (QVA149), its monocomponents, and tiotropium versus placebo in COPD patients
-
Wedzicha JA, Dahl R, Buhl R, et al. Pooled safety analysis of the fixed-dose combination of indacaterol and glycopyrronium (QVA149), its monocomponents, and tiotropium versus placebo in COPD patients. Respir Med 2014, 108:1498-1507.
-
(2014)
Respir Med
, vol.108
, pp. 1498-1507
-
-
Wedzicha, J.A.1
Dahl, R.2
Buhl, R.3
-
57
-
-
84946575010
-
FLIGHT: efficacy and safety of QVA149 (indacaterol/glycopyrrolate) versus its monocomponents and placebo in patients with COPD
-
Mahler DA, Kerwin E, Ayers T, et al. FLIGHT: efficacy and safety of QVA149 (indacaterol/glycopyrrolate) versus its monocomponents and placebo in patients with COPD. Am J Respir Crit Care Med 2015, 192:1068-1079.
-
(2015)
Am J Respir Crit Care Med
, vol.192
, pp. 1068-1079
-
-
Mahler, D.A.1
Kerwin, E.2
Ayers, T.3
-
58
-
-
84904081919
-
Safety and tolerability of once-daily umeclidinium/vilanterol 125/25 mcg and umeclidinium 125 mcg in patients with chronic obstructive pulmonary disease: results from a 52-week, randomized, double-blind, placebo-controlled study
-
Donohue JF, Niewoehner D, Brooks J, O'Dell D, Church A Safety and tolerability of once-daily umeclidinium/vilanterol 125/25 mcg and umeclidinium 125 mcg in patients with chronic obstructive pulmonary disease: results from a 52-week, randomized, double-blind, placebo-controlled study. Respir Res 2014, 15:78.
-
(2014)
Respir Res
, vol.15
, pp. 78
-
-
Donohue, J.F.1
Niewoehner, D.2
Brooks, J.3
O'Dell, D.4
Church, A.5
-
59
-
-
84899863235
-
Once-daily umeclidinium/vilanterol 125/25 mcg in COPD: a randomized, controlled study
-
Celli B, Crater G, Kilbride S, et al. Once-daily umeclidinium/vilanterol 125/25 mcg in COPD: a randomized, controlled study. Chest 2014, 145:981-991.
-
(2014)
Chest
, vol.145
, pp. 981-991
-
-
Celli, B.1
Crater, G.2
Kilbride, S.3
-
60
-
-
84926500092
-
Tiotropium and olodaterol fixed-dose combination versus mono-components in COPD (GOLD 2-4)
-
Buhl R, Maltais F, Abrahams R, et al. Tiotropium and olodaterol fixed-dose combination versus mono-components in COPD (GOLD 2-4). Eur Respir J 2015, 45:969-979.
-
(2015)
Eur Respir J
, vol.45
, pp. 969-979
-
-
Buhl, R.1
Maltais, F.2
Abrahams, R.3
-
61
-
-
84942987543
-
Tiotropium + olodaterol shows clinically meaningful improvements in quality of life
-
Singh D, Ferguson GT, Bolitschek J, et al. Tiotropium + olodaterol shows clinically meaningful improvements in quality of life. Respir Med 2015, 109:1312-1319.
-
(2015)
Respir Med
, vol.109
, pp. 1312-1319
-
-
Singh, D.1
Ferguson, G.T.2
Bolitschek, J.3
-
62
-
-
84921459850
-
Efficacy and safety of aclidinium bromide/formoterol fumarate fixed-dose combinations compared with individual components and placebo in patients with COPD (ACLIFORM-COPD): a multicentre, randomised study
-
Singh D, Jones PW, Bateman ED, et al. Efficacy and safety of aclidinium bromide/formoterol fumarate fixed-dose combinations compared with individual components and placebo in patients with COPD (ACLIFORM-COPD): a multicentre, randomised study. BMC Pulm Med 2014, 14:178.
-
(2014)
BMC Pulm Med
, vol.14
, pp. 178
-
-
Singh, D.1
Jones, P.W.2
Bateman, E.D.3
-
63
-
-
84965085606
-
Efficacy and safety of fixed-dose combinations of aclidinium bromide/formoterol fumarate: the 24-week, randomized, placebo-controlled AUGMENT COPD study
-
the AUGMENT COPD study investigators
-
D'Urzo AD, Rennard SI, Kerwin EM, Mergel V, Leselbaum AR, Caracta CF Efficacy and safety of fixed-dose combinations of aclidinium bromide/formoterol fumarate: the 24-week, randomized, placebo-controlled AUGMENT COPD study. Respir Res 2014, 15:123. the AUGMENT COPD study investigators.
-
(2014)
Respir Res
, vol.15
, pp. 123
-
-
D'Urzo, A.D.1
Rennard, S.I.2
Kerwin, E.M.3
Mergel, V.4
Leselbaum, A.R.5
Caracta, C.F.6
-
65
-
-
9744245399
-
Methylxanthines for exacerbations of chronic obstructive pulmonary disease
-
Barr RG, Rowe BH, Camargo CA Methylxanthines for exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2003, 2. CD002168.
-
(2003)
Cochrane Database Syst Rev
, vol.2
-
-
Barr, R.G.1
Rowe, B.H.2
Camargo, C.A.3
-
67
-
-
44949272227
-
Acute bronchodilating effects of ipratropium bromide and theophylline in chronic obstructive pulmonary disease
-
Bleecker ER, Britt EJ Acute bronchodilating effects of ipratropium bromide and theophylline in chronic obstructive pulmonary disease. Am J Med 1991, 91:24S-27S.
-
(1991)
Am J Med
, vol.91
, pp. 24S-27S
-
-
Bleecker, E.R.1
Britt, E.J.2
-
68
-
-
0034892541
-
Salmeterol plus theophylline combination therapy in the treatment of COPD
-
ZuWallack RL, Mahler DA, Reilly D, et al. Salmeterol plus theophylline combination therapy in the treatment of COPD. Chest 2001, 119:1661-1670.
-
(2001)
Chest
, vol.119
, pp. 1661-1670
-
-
ZuWallack, R.L.1
Mahler, D.A.2
Reilly, D.3
-
69
-
-
0025738570
-
The arrhythmogenicity of theophylline. A multivariate analysis of clinical determinants
-
Bittar G, Friedman HS The arrhythmogenicity of theophylline. A multivariate analysis of clinical determinants. Chest 1991, 99:1415-1420.
-
(1991)
Chest
, vol.99
, pp. 1415-1420
-
-
Bittar, G.1
Friedman, H.S.2
-
70
-
-
0019844439
-
Cardiac arrhythmias due to oral aminophylline in patients with chronic obstructive pulmonary disease
-
Patel AK, Skatrud JB, Thomsen JH Cardiac arrhythmias due to oral aminophylline in patients with chronic obstructive pulmonary disease. Chest 1981, 80:661-665.
-
(1981)
Chest
, vol.80
, pp. 661-665
-
-
Patel, A.K.1
Skatrud, J.B.2
Thomsen, J.H.3
-
71
-
-
0025052503
-
Cardiac arrhythmias during theophylline toxicity. A prospective continuous electrocardiographic study
-
Sessler CN, Cohen MD Cardiac arrhythmias during theophylline toxicity. A prospective continuous electrocardiographic study. Chest 1990, 98:672-678.
-
(1990)
Chest
, vol.98
, pp. 672-678
-
-
Sessler, C.N.1
Cohen, M.D.2
-
72
-
-
17844399598
-
Respiratory medications and the risk of cardiac arrhythmias
-
Huerta C, Lanes SF, García Rodríguez LA Respiratory medications and the risk of cardiac arrhythmias. Epidemiology 2005, 16:360-366.
-
(2005)
Epidemiology
, vol.16
, pp. 360-366
-
-
Huerta, C.1
Lanes, S.F.2
García Rodríguez, L.A.3
-
73
-
-
51949090107
-
Risk for death associated with medications for recently diagnosed chronic obstructive pulmonary disease
-
Lee TA, Pickard AS, Au DH, Bartle B, Weiss KB Risk for death associated with medications for recently diagnosed chronic obstructive pulmonary disease. Ann Intern Med 2008, 149:380-390.
-
(2008)
Ann Intern Med
, vol.149
, pp. 380-390
-
-
Lee, T.A.1
Pickard, A.S.2
Au, D.H.3
Bartle, B.4
Weiss, K.B.5
-
74
-
-
0023098988
-
Theophylline-induced alterations in cardiac electrophysiology in patients with chronic obstructive pulmonary disease
-
Eiriksson CE, Writer SL, Vestal RE Theophylline-induced alterations in cardiac electrophysiology in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 1987, 135:322-326.
-
(1987)
Am Rev Respir Dis
, vol.135
, pp. 322-326
-
-
Eiriksson, C.E.1
Writer, S.L.2
Vestal, R.E.3
-
75
-
-
69149103642
-
Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials
-
the M2-124 and M2-125 study groups
-
Calverley PM, Rabe KF, Goehring UM, Kristiansen S, Fabbri LM, Martinez FJ Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials. Lancet 2009, 374:685-694. the M2-124 and M2-125 study groups.
-
(2009)
Lancet
, vol.374
, pp. 685-694
-
-
Calverley, P.M.1
Rabe, K.F.2
Goehring, U.M.3
Kristiansen, S.4
Fabbri, L.M.5
Martinez, F.J.6
-
76
-
-
84924250308
-
Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial
-
Martinez FJ, Calverley PM, Goehring UM, Brose M, Fabbri LM, Rabe KF Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial. Lancet 2015, 385:857-866.
-
(2015)
Lancet
, vol.385
, pp. 857-866
-
-
Martinez, F.J.1
Calverley, P.M.2
Goehring, U.M.3
Brose, M.4
Fabbri, L.M.5
Rabe, K.F.6
-
77
-
-
65949098180
-
Safety profile of the respiratory fluoroquinolone moxifloxacin: comparison with other fluoroquinolones and other antibacterial classes
-
Van Bambeke F, Tulkens PM Safety profile of the respiratory fluoroquinolone moxifloxacin: comparison with other fluoroquinolones and other antibacterial classes. Drug Saf 2009, 32:359-378.
-
(2009)
Drug Saf
, vol.32
, pp. 359-378
-
-
Van Bambeke, F.1
Tulkens, P.M.2
-
78
-
-
84907202561
-
Management and prevention of exacerbations of COPD
-
Aaron SD Management and prevention of exacerbations of COPD. BMJ 2014, 349:g5237.
-
(2014)
BMJ
, vol.349
, pp. g5237
-
-
Aaron, S.D.1
-
79
-
-
84864745071
-
Macrolide effects on the prevention of COPD exacerbations
-
Yamaya M, Azuma A, Takizawa H, Kadota J, Tamaoki J, Kudoh S Macrolide effects on the prevention of COPD exacerbations. Eur Respir J 2012, 40:485-494.
-
(2012)
Eur Respir J
, vol.40
, pp. 485-494
-
-
Yamaya, M.1
Azuma, A.2
Takizawa, H.3
Kadota, J.4
Tamaoki, J.5
Kudoh, S.6
-
81
-
-
30344462409
-
Prolonged QTc interval and risk of sudden cardiac death in a population of older adults
-
Straus SM, Kors JA, De Bruin ML, et al. Prolonged QTc interval and risk of sudden cardiac death in a population of older adults. J Am Coll Cardiol 2006, 47:362-367.
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 362-367
-
-
Straus, S.M.1
Kors, J.A.2
De Bruin, M.L.3
-
82
-
-
0344492207
-
Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
-
Redfern WS, Carlsson L, Davis AS, et al. Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development. Cardiovasc Res 2003, 58:32-45.
-
(2003)
Cardiovasc Res
, vol.58
, pp. 32-45
-
-
Redfern, W.S.1
Carlsson, L.2
Davis, A.S.3
-
83
-
-
84861076083
-
Azithromycin and the risk of cardiovascular death
-
Ray WA, Murray KT, Hall K, Arbogast PG, Stein CM Azithromycin and the risk of cardiovascular death. N Engl J Med 2012, 366:1881-1890.
-
(2012)
N Engl J Med
, vol.366
, pp. 1881-1890
-
-
Ray, W.A.1
Murray, K.T.2
Hall, K.3
Arbogast, P.G.4
Stein, C.M.5
-
84
-
-
84877254751
-
Use of azithromycin and death from cardiovascular causes
-
Svanström H, Pasternak B, Hviid A Use of azithromycin and death from cardiovascular causes. N Engl J Med 2013, 368:1704-1712.
-
(2013)
N Engl J Med
, vol.368
, pp. 1704-1712
-
-
Svanström, H.1
Pasternak, B.2
Hviid, A.3
-
85
-
-
84877267913
-
Cardiovascular risks with azithromycin and other antibacterial drugs
-
Mosholder AD, Mathew J, Alexander JJ, Smith H, Nambiar S Cardiovascular risks with azithromycin and other antibacterial drugs. N Engl J Med 2013, 368:1665-1668.
-
(2013)
N Engl J Med
, vol.368
, pp. 1665-1668
-
-
Mosholder, A.D.1
Mathew, J.2
Alexander, J.J.3
Smith, H.4
Nambiar, S.5
-
86
-
-
36549040492
-
In defense of pharmacoepidemiology-embracing the yin and yang of drug research
-
Avorn J In defense of pharmacoepidemiology-embracing the yin and yang of drug research. N Engl J Med 2007, 357:2219-2221.
-
(2007)
N Engl J Med
, vol.357
, pp. 2219-2221
-
-
Avorn, J.1
-
87
-
-
84888865885
-
Integrating real-life studies in the global therapeutic research framework
-
the Respiratory Effectiveness Group
-
Roche N, Reddel HK, Agusti A, et al. Integrating real-life studies in the global therapeutic research framework. Lancet Respir Med 2013, 1:e29-e30. the Respiratory Effectiveness Group.
-
(2013)
Lancet Respir Med
, vol.1
, pp. e29-e30
-
-
Roche, N.1
Reddel, H.K.2
Agusti, A.3
|