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Volumn 4, Issue 11, 2016, Pages 911-924

Management of chronic obstructive pulmonary disease beyond the lungs

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMFEBUTAMONE; ANTIDEPRESSANT AGENT; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BISOPROLOL; BOSENTAN; CARVEDILOL; CELIPROLOL; CLOPIDOGREL; CORTICOSTEROID DERIVATIVE; DAPAGLIFLOZIN; DEXMEDETOMIDINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ILOPROST; INSULIN; LANSOPRAZOLE; LOSARTAN; METFORMIN; METOPROLOL; MORPHINE; PLACEBO; PROTON PUMP INHIBITOR; ROFLUMILAST; SIMVASTATIN; TADALAFIL; TICAGRELOR; UNINDEXED DRUG; VITAMIN D;

EID: 84971607470     PISSN: 22132600     EISSN: 22132619     Source Type: Journal    
DOI: 10.1016/S2213-2600(16)00097-7     Document Type: Review
Times cited : (150)

References (104)
  • 1
    • 84875847989 scopus 로고    scopus 로고
    • Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease
    • 1 Vanfleteren, LE, Spruit, MA, Groenen, M, et al. Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 187 (2013), 728–735.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 728-735
    • Vanfleteren, L.E.1    Spruit, M.A.2    Groenen, M.3
  • 2
    • 0032552240 scopus 로고    scopus 로고
    • Effect of beta-blockade on mortality among high-risk and low-risk patients after myocardial infarction
    • 2 Gottlieb, SS, McCarter, RJ, Vogel, RA, Effect of beta-blockade on mortality among high-risk and low-risk patients after myocardial infarction. N Engl J Med 339 (1998), 489–497.
    • (1998) N Engl J Med , vol.339 , pp. 489-497
    • Gottlieb, S.S.1    McCarter, R.J.2    Vogel, R.A.3
  • 3
    • 77957705828 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease phenotypes: the future of COPD
    • 3 Han, MK, Agusti, A, Calverley, PM, et al. Chronic obstructive pulmonary disease phenotypes: the future of COPD. Am J Respir Crit Care Med 182 (2010), 598–604.
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 598-604
    • Han, M.K.1    Agusti, A.2    Calverley, P.M.3
  • 4
    • 84873956600 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
    • 4 Vestbo, J, Hurd, SS, Agustí, AG, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 187 (2013), 347–365.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 347-365
    • Vestbo, J.1    Hurd, S.S.2    Agustí, A.G.3
  • 6
    • 84929661059 scopus 로고    scopus 로고
    • Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management
    • 6 Woodruff, PG, Agusti, A, Roche, N, Singh, D, Martinez, FJ, Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management. Lancet 385 (2015), 1789–1798.
    • (2015) Lancet , vol.385 , pp. 1789-1798
    • Woodruff, P.G.1    Agusti, A.2    Roche, N.3    Singh, D.4    Martinez, F.J.5
  • 8
    • 84875863341 scopus 로고    scopus 로고
    • Echocardiographic abnormalities in patients with COPD at their first hospital admission
    • 8 Freixa, X, Portillo, K, Pare, C, et al. Echocardiographic abnormalities in patients with COPD at their first hospital admission. Eur Respir J 41 (2013), 784–791.
    • (2013) Eur Respir J , vol.41 , pp. 784-791
    • Freixa, X.1    Portillo, K.2    Pare, C.3
  • 9
    • 80955133278 scopus 로고    scopus 로고
    • Frequency and relevance of ischemic electrocardiographic findings in patients with chronic obstructive pulmonary disease
    • 9 Vanfleteren, LE, Franssen, FM, Uszko-Lencer, NH, et al. Frequency and relevance of ischemic electrocardiographic findings in patients with chronic obstructive pulmonary disease. Am J Cardiol 108 (2011), 1669–1674.
    • (2011) Am J Cardiol , vol.108 , pp. 1669-1674
    • Vanfleteren, L.E.1    Franssen, F.M.2    Uszko-Lencer, N.H.3
  • 11
    • 70350088412 scopus 로고    scopus 로고
    • The metabolic syndrome in patients with chronic bronchitis and COPD: frequency and associated consequences for systemic inflammation and physical inactivity
    • 11 Watz, H, Waschki, B, Kirsten, A, et al. The metabolic syndrome in patients with chronic bronchitis and COPD: frequency and associated consequences for systemic inflammation and physical inactivity. Chest 136 (2009), 1039–1046.
    • (2009) Chest , vol.136 , pp. 1039-1046
    • Watz, H.1    Waschki, B.2    Kirsten, A.3
  • 12
    • 84860343774 scopus 로고    scopus 로고
    • Subclinical atherosclerosis, airflow obstruction and emphysema: the MESA Lung Study
    • 12 Barr, RG, Ahmed, FS, Carr, JJ, et al. Subclinical atherosclerosis, airflow obstruction and emphysema: the MESA Lung Study. Eur Respir J 39 (2012), 846–854.
    • (2012) Eur Respir J , vol.39 , pp. 846-854
    • Barr, R.G.1    Ahmed, F.S.2    Carr, J.J.3
  • 13
    • 37149001796 scopus 로고    scopus 로고
    • Impaired flow-mediated dilation is associated with low pulmonary function and emphysema in ex-smokers: the Emphysema and Cancer Action Project (EMCAP) Study
    • 13 Barr, RG, Mesia-Vela, S, Austin, JH, et al. Impaired flow-mediated dilation is associated with low pulmonary function and emphysema in ex-smokers: the Emphysema and Cancer Action Project (EMCAP) Study. Am J Respir Crit Care Med 176 (2007), 1200–1207.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 1200-1207
    • Barr, R.G.1    Mesia-Vela, S.2    Austin, J.H.3
  • 14
    • 37149042861 scopus 로고    scopus 로고
    • Arterial stiffness is independently associated with emphysema severity in patients with chronic obstructive pulmonary disease
    • 14 McAllister, DA, Maclay, JD, Mills, NL, et al. Arterial stiffness is independently associated with emphysema severity in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 176 (2007), 1208–1214.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 1208-1214
    • McAllister, D.A.1    Maclay, J.D.2    Mills, N.L.3
  • 15
    • 84938883507 scopus 로고    scopus 로고
    • Lung volume reduction surgery and improvement of endothelial function and blood pressure in patients with chronic obstructive pulmonary disease. A randomized controlled trial
    • 15 Clarenbach, CF, Sievi, NA, Brock, M, Schneiter, D, Weder, W, Kohler, M, Lung volume reduction surgery and improvement of endothelial function and blood pressure in patients with chronic obstructive pulmonary disease. A randomized controlled trial. Am J Respir Crit Care Med 192 (2015), 307–314.
    • (2015) Am J Respir Crit Care Med , vol.192 , pp. 307-314
    • Clarenbach, C.F.1    Sievi, N.A.2    Brock, M.3    Schneiter, D.4    Weder, W.5    Kohler, M.6
  • 17
    • 15844399396 scopus 로고    scopus 로고
    • Detrimental effects of beta-blockers in COPD: a concern for nonselective beta-blockers
    • 17 van der Woude, HJ, Zaagsma, J, Postma, DS, Winter, TH, van Hulst, M, Aalbers, R, Detrimental effects of beta-blockers in COPD: a concern for nonselective beta-blockers. Chest 127 (2005), 818–824.
    • (2005) Chest , vol.127 , pp. 818-824
    • van der Woude, H.J.1    Zaagsma, J.2    Postma, D.S.3    Winter, T.H.4    van Hulst, M.5    Aalbers, R.6
  • 18
    • 11344252836 scopus 로고    scopus 로고
    • Beta-blockers as single-agent therapy for hypertension and the risk of mortality among patients with chronic obstructive pulmonary disease
    • 18 Au, DH, Bryson, CL, Fan, VS, et al. Beta-blockers as single-agent therapy for hypertension and the risk of mortality among patients with chronic obstructive pulmonary disease. Am J Med 117 (2004), 925–931.
    • (2004) Am J Med , vol.117 , pp. 925-931
    • Au, D.H.1    Bryson, C.L.2    Fan, V.S.3
  • 19
    • 77952707904 scopus 로고    scopus 로고
    • Beta-blockers may reduce mortality and risk of exacerbations in patients with chronic obstructive pulmonary disease
    • 19 Rutten, FH, Zuithoff, NP, Hak, E, Grobbee, DE, Hoes, AW, Beta-blockers may reduce mortality and risk of exacerbations in patients with chronic obstructive pulmonary disease. Arch Intern Med 170 (2010), 880–887.
    • (2010) Arch Intern Med , vol.170 , pp. 880-887
    • Rutten, F.H.1    Zuithoff, N.P.2    Hak, E.3    Grobbee, D.E.4    Hoes, A.W.5
  • 20
    • 79955952987 scopus 로고    scopus 로고
    • Effect of beta blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study
    • 20 Short, PM, Lipworth, SI, Elder, DH, Schembri, S, Lipworth, BJ, Effect of beta blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study. BMJ, 342, 2011, d2549.
    • (2011) BMJ , vol.342 , pp. d2549
    • Short, P.M.1    Lipworth, S.I.2    Elder, D.H.3    Schembri, S.4    Lipworth, B.J.5
  • 21
    • 41849085549 scopus 로고    scopus 로고
    • Use of beta blockers and the risk of death in hospitalised patients with acute exacerbations of COPD
    • 21 Dransfield, MT, Rowe, SM, Johnson, JE, Bailey, WC, Gerald, LB, Use of beta blockers and the risk of death in hospitalised patients with acute exacerbations of COPD. Thorax 63 (2008), 301–305.
    • (2008) Thorax , vol.63 , pp. 301-305
    • Dransfield, M.T.1    Rowe, S.M.2    Johnson, J.E.3    Bailey, W.C.4    Gerald, L.B.5
  • 22
    • 84868198047 scopus 로고    scopus 로고
    • Association between β-blocker therapy and outcomes in patients hospitalised with acute exacerbations of chronic obstructive lung disease with underlying ischaemic heart disease, heart failure or hypertension
    • 22 Stefan, MS, Rothberg, MB, Priya, A, Pekow, PS, Au, DH, Lindenauer, PK, Association between β-blocker therapy and outcomes in patients hospitalised with acute exacerbations of chronic obstructive lung disease with underlying ischaemic heart disease, heart failure or hypertension. Thorax 67 (2012), 977–984.
    • (2012) Thorax , vol.67 , pp. 977-984
    • Stefan, M.S.1    Rothberg, M.B.2    Priya, A.3    Pekow, P.S.4    Au, D.H.5    Lindenauer, P.K.6
  • 24
    • 84929273086 scopus 로고    scopus 로고
    • Resting heart rate is a risk factor for mortality in chronic obstructive pulmonary disease, but not for exacerbations or pneumonia
    • 24 Warnier, MJ, Rutten, FH, de Boer, A, Hoes, AW, De Bruin, ML, Resting heart rate is a risk factor for mortality in chronic obstructive pulmonary disease, but not for exacerbations or pneumonia. PLoS One, 9, 2014, e105152.
    • (2014) PLoS One , vol.9 , pp. e105152
    • Warnier, M.J.1    Rutten, F.H.2    de Boer, A.3    Hoes, A.W.4    De Bruin, M.L.5
  • 25
    • 84958109521 scopus 로고    scopus 로고
    • Cardiac effects of current treatments of chronic obstructive pulmonary disease
    • 25 Lahousse, L, Verhamme, KM, Stricker, BH, Brusselle, GG, Cardiac effects of current treatments of chronic obstructive pulmonary disease. Lancet Respir Med 4 (2016), 149–164.
    • (2016) Lancet Respir Med , vol.4 , pp. 149-164
    • Lahousse, L.1    Verhamme, K.M.2    Stricker, B.H.3    Brusselle, G.G.4
  • 26
    • 0038467503 scopus 로고    scopus 로고
    • Risk of mortality and heart failure exacerbations associated with inhaled beta-adrenoceptor agonists among patients with known left ventricular systolic dysfunction
    • 26 Au, DH, Udris, EM, Fan, VS, Curtis, JR, McDonell, MB, Fihn, SD, Risk of mortality and heart failure exacerbations associated with inhaled beta-adrenoceptor agonists among patients with known left ventricular systolic dysfunction. Chest 123 (2003), 1964–1969.
    • (2003) Chest , vol.123 , pp. 1964-1969
    • Au, D.H.1    Udris, E.M.2    Fan, V.S.3    Curtis, J.R.4    McDonell, M.B.5    Fihn, S.D.6
  • 28
    • 84898757849 scopus 로고    scopus 로고
    • Adverse respiratory effect of acute β-blocker exposure in asthma: a systematic review and meta-analysis of randomized controlled trials
    • 28 Morales, DR, Jackson, C, Lipworth, BJ, Donnan, PT, Guthrie, B, Adverse respiratory effect of acute β-blocker exposure in asthma: a systematic review and meta-analysis of randomized controlled trials. Chest 145 (2014), 779–786.
    • (2014) Chest , vol.145 , pp. 779-786
    • Morales, D.R.1    Jackson, C.2    Lipworth, B.J.3    Donnan, P.T.4    Guthrie, B.5
  • 29
    • 77949648516 scopus 로고    scopus 로고
    • Cardio-selective and non-selective beta-blockers in chronic obstructive pulmonary disease: effects on bronchodilator response and exercise
    • 29 Chang, CL, Mills, GD, McLachlan, JD, Karalus, NC, Hancox, RJ, Cardio-selective and non-selective beta-blockers in chronic obstructive pulmonary disease: effects on bronchodilator response and exercise. Intern Med J 40 (2010), 193–200.
    • (2010) Intern Med J , vol.40 , pp. 193-200
    • Chang, C.L.1    Mills, G.D.2    McLachlan, J.D.3    Karalus, N.C.4    Hancox, R.J.5
  • 30
    • 33744994082 scopus 로고    scopus 로고
    • Reduction of morbidity and mortality by statins, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers in patients with chronic obstructive pulmonary disease
    • 30 Mancini, GB, Etminan, M, Zhang, B, Levesque, LE, FitzGerald, JM, Brophy, JM, Reduction of morbidity and mortality by statins, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers in patients with chronic obstructive pulmonary disease. J Am Coll Cardiol 47 (2006), 2554–2560.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 2554-2560
    • Mancini, G.B.1    Etminan, M.2    Zhang, B.3    Levesque, L.E.4    FitzGerald, J.M.5    Brophy, J.M.6
  • 31
    • 84905395877 scopus 로고    scopus 로고
    • Statins reduce all-cause mortality in chronic obstructive pulmonary disease: a systematic review and meta-analysis of observational studies
    • 31 Horita, N, Miyazawa, N, Kojima, R, et al. Statins reduce all-cause mortality in chronic obstructive pulmonary disease: a systematic review and meta-analysis of observational studies. Respir Res, 15, 2014, 80.
    • (2014) Respir Res , vol.15 , pp. 80
    • Horita, N.1    Miyazawa, N.2    Kojima, R.3
  • 32
    • 84879163490 scopus 로고    scopus 로고
    • Statin use and risk of COPD exacerbation requiring hospitalization
    • e2.
    • 32 Wang, MT, Lo, YW, Tsai, CL, et al. Statin use and risk of COPD exacerbation requiring hospitalization. Am J Med 126 (2013), 598–606 e2.
    • (2013) Am J Med , vol.126 , pp. 598-606
    • Wang, M.T.1    Lo, Y.W.2    Tsai, C.L.3
  • 33
    • 72549095179 scopus 로고    scopus 로고
    • COPD and cancer mortality: the influence of statins
    • 33 van Gestel, YR, Hoeks, SE, Sin, DD, et al. COPD and cancer mortality: the influence of statins. Thorax 64 (2009), 963–967.
    • (2009) Thorax , vol.64 , pp. 963-967
    • van Gestel, Y.R.1    Hoeks, S.E.2    Sin, D.D.3
  • 34
    • 84901817055 scopus 로고    scopus 로고
    • Simvastatin for the prevention of exacerbations in moderate-to-severe COPD
    • 34 Criner, GJ, Connett, JE, Aaron, SD, et al. the COPD Clinical Research Network, the Canadian Institutes of Health Research. Simvastatin for the prevention of exacerbations in moderate-to-severe COPD. N Engl J Med 370 (2014), 2201–2210.
    • (2014) N Engl J Med , vol.370 , pp. 2201-2210
    • Criner, G.J.1    Connett, J.E.2    Aaron, S.D.3
  • 35
    • 84902254011 scopus 로고    scopus 로고
    • Thrombocytosis is associated with increased short and long term mortality after exacerbation of chronic obstructive pulmonary disease: a role for antiplatelet therapy?
    • 35 Harrison, MT, Short, P, Williamson, PA, Singanayagam, A, Chalmers, JD, Schembri, S, Thrombocytosis is associated with increased short and long term mortality after exacerbation of chronic obstructive pulmonary disease: a role for antiplatelet therapy?. Thorax 69 (2014), 609–615.
    • (2014) Thorax , vol.69 , pp. 609-615
    • Harrison, M.T.1    Short, P.2    Williamson, P.A.3    Singanayagam, A.4    Chalmers, J.D.5    Schembri, S.6
  • 36
    • 84902240380 scopus 로고    scopus 로고
    • The devastating power of platelets in COPD exacerbations: can aspirin save lives in COPD?
    • 36 Sin, DD, The devastating power of platelets in COPD exacerbations: can aspirin save lives in COPD?. Thorax 69 (2014), 603–604.
    • (2014) Thorax , vol.69 , pp. 603-604
    • Sin, D.D.1
  • 37
    • 80051898444 scopus 로고    scopus 로고
    • Increased platelet activation in patients with stable and acute exacerbation of COPD
    • 37 Maclay, JD, McAllister, DA, Johnston, S, et al. Increased platelet activation in patients with stable and acute exacerbation of COPD. Thorax 66 (2011), 769–774.
    • (2011) Thorax , vol.66 , pp. 769-774
    • Maclay, J.D.1    McAllister, D.A.2    Johnston, S.3
  • 38
    • 84923646672 scopus 로고    scopus 로고
    • Comparing cardiopulmonary exercise testing in severe COPD patients with and without pulmonary hypertension
    • 38 Thirapatarapong, W, Armstrong, HF, Bartels, MN, Comparing cardiopulmonary exercise testing in severe COPD patients with and without pulmonary hypertension. Heart Lung Circ 23 (2014), 833–840.
    • (2014) Heart Lung Circ , vol.23 , pp. 833-840
    • Thirapatarapong, W.1    Armstrong, H.F.2    Bartels, M.N.3
  • 39
    • 84897957796 scopus 로고    scopus 로고
    • Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial
    • 39 Goudie, AR, Lipworth, BJ, Hopkinson, PJ, Wei, L, Struthers, AD, Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial. Lancet Respir Med 2 (2014), 293–300.
    • (2014) Lancet Respir Med , vol.2 , pp. 293-300
    • Goudie, A.R.1    Lipworth, B.J.2    Hopkinson, P.J.3    Wei, L.4    Struthers, A.D.5
  • 40
    • 84903376871 scopus 로고    scopus 로고
    • Prevalence of metabolic syndrome in COPD patients and its consequences
    • 40 Breyer, MK, Spruit, MA, Hanson, CK, et al. Prevalence of metabolic syndrome in COPD patients and its consequences. PLoS One, 9, 2014, e98013.
    • (2014) PLoS One , vol.9 , pp. e98013
    • Breyer, M.K.1    Spruit, M.A.2    Hanson, C.K.3
  • 41
    • 84924770388 scopus 로고    scopus 로고
    • The association between glucose levels and hospital outcomes in patients with acute exacerbations of chronic obstructive pulmonary disease
    • 41 Islam, EA, Limsuwat, C, Nantsupawat, T, Berdine, GG, Nugent, KM, The association between glucose levels and hospital outcomes in patients with acute exacerbations of chronic obstructive pulmonary disease. Ann Thorac Med 10 (2015), 94–99.
    • (2015) Ann Thorac Med , vol.10 , pp. 94-99
    • Islam, E.A.1    Limsuwat, C.2    Nantsupawat, T.3    Berdine, G.G.4    Nugent, K.M.5
  • 42
    • 84959269187 scopus 로고    scopus 로고
    • Metformin in CTT. Metformin in severe exacerbations of chronic obstructive pulmonary disease: a randomised controlled trial
    • published online Feb 25.
    • 42 Hitchings, AW, Lai, D, Jones, PW, Baker, EH, Metformin in CTT. Metformin in severe exacerbations of chronic obstructive pulmonary disease: a randomised controlled trial. Thorax, 2016, 10.1136/thoraxjnl-2015-208035 published online Feb 25.
    • (2016) Thorax
    • Hitchings, A.W.1    Lai, D.2    Jones, P.W.3    Baker, E.H.4
  • 44
    • 84897074033 scopus 로고    scopus 로고
    • Respiratory effects of insulin sensitisation with metformin: a prospective observational study
    • 44 Sexton, P, Metcalf, P, Kolbe, J, Respiratory effects of insulin sensitisation with metformin: a prospective observational study. COPD 11 (2014), 133–142.
    • (2014) COPD , vol.11 , pp. 133-142
    • Sexton, P.1    Metcalf, P.2    Kolbe, J.3
  • 45
    • 69149098943 scopus 로고    scopus 로고
    • Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials
    • 45 Fabbri, LM, Calverley, PM, Izquierdo-Alonso, JL, et al., the M2-127 and M2-128 study groups. Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials. Lancet 374 (2009), 695–703.
    • (2009) Lancet , vol.374 , pp. 695-703
    • Fabbri, L.M.1    Calverley, P.M.2    Izquierdo-Alonso, J.L.3
  • 46
    • 84924250308 scopus 로고    scopus 로고
    • Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial
    • 46 Martinez, FJ, Calverley, PM, Goehring, UM, Brose, M, Fabbri, LM, Rabe, KF, Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial. Lancet 385 (2015), 857–866.
    • (2015) Lancet , vol.385 , pp. 857-866
    • Martinez, F.J.1    Calverley, P.M.2    Goehring, U.M.3    Brose, M.4    Fabbri, L.M.5    Rabe, K.F.6
  • 47
    • 84866148535 scopus 로고    scopus 로고
    • Effect of the phosphodiesterase 4 inhibitor roflumilast on glucose metabolism in patients with treatment-naive, newly diagnosed type 2 diabetes mellitus
    • 47 Wouters, EF, Bredenbröker, D, Teichmann, P, et al. Effect of the phosphodiesterase 4 inhibitor roflumilast on glucose metabolism in patients with treatment-naive, newly diagnosed type 2 diabetes mellitus. J Clin Endocrinol Metab 97 (2012), E1720–E1725.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. E1720-E1725
    • Wouters, E.F.1    Bredenbröker, D.2    Teichmann, P.3
  • 48
    • 33745420502 scopus 로고    scopus 로고
    • Prevalence of nutritional depletion in a large out-patient population of patients with COPD
    • 48 Vermeeren, MA, Creutzberg, EC, Schols, AM, et al., the COSMIC Study Group. Prevalence of nutritional depletion in a large out-patient population of patients with COPD. Respir Med 100 (2006), 1349–1355.
    • (2006) Respir Med , vol.100 , pp. 1349-1355
    • Vermeeren, M.A.1    Creutzberg, E.C.2    Schols, A.M.3
  • 49
    • 0027247516 scopus 로고
    • Anthropometric and pulmonary function test profiles of outpatients with stable chronic obstructive pulmonary disease
    • 49 Sahebjami, H, Doers, JT, Render, ML, Bond, TL, Anthropometric and pulmonary function test profiles of outpatients with stable chronic obstructive pulmonary disease. Am J Med 94 (1993), 469–474.
    • (1993) Am J Med , vol.94 , pp. 469-474
    • Sahebjami, H.1    Doers, J.T.2    Render, M.L.3    Bond, T.L.4
  • 50
    • 0024371064 scopus 로고
    • Body weight in chronic obstructive pulmonary disease: the National Institutes of Health Intermittent Positive-Pressure Breathing Trial
    • 50 Wilson, DO, Rogers, RM, Wright, EC, Anthonisen, NR, Body weight in chronic obstructive pulmonary disease: the National Institutes of Health Intermittent Positive-Pressure Breathing Trial. Am Rev Respir Dis 139 (1989), 1435–1438.
    • (1989) Am Rev Respir Dis , vol.139 , pp. 1435-1438
    • Wilson, D.O.1    Rogers, R.M.2    Wright, E.C.3    Anthonisen, N.R.4
  • 51
    • 80054122922 scopus 로고    scopus 로고
    • Is age-related decline in lean mass and physical function accelerated by obstructive lung disease or smoking?
    • 51 van den Borst, B, Koster, A, Yu, B, et al. Is age-related decline in lean mass and physical function accelerated by obstructive lung disease or smoking?. Thorax 66 (2011), 961–969.
    • (2011) Thorax , vol.66 , pp. 961-969
    • van den Borst, B.1    Koster, A.2    Yu, B.3
  • 52
    • 0031862418 scopus 로고    scopus 로고
    • Weight loss is a reversible factor in the prognosis of chronic obstructive pulmonary disease
    • 52 Schols, AM, Slangen, J, Volovics, L, Wouters, EF, Weight loss is a reversible factor in the prognosis of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 157 (1998), 1791–1797.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 1791-1797
    • Schols, A.M.1    Slangen, J.2    Volovics, L.3    Wouters, E.F.4
  • 53
    • 84874204081 scopus 로고    scopus 로고
    • Nutritional supplementation for stable chronic obstructive pulmonary disease
    • CD000998
    • 53 Ferreira, IM, Brooks, D, White, J, Goldstein, R, Nutritional supplementation for stable chronic obstructive pulmonary disease. Cochrane Database Syst Rev, 12, 2012 CD000998.
    • (2012) Cochrane Database Syst Rev , vol.12
    • Ferreira, I.M.1    Brooks, D.2    White, J.3    Goldstein, R.4
  • 54
    • 30344482545 scopus 로고    scopus 로고
    • Body mass, fat-free body mass, and prognosis in patients with chronic obstructive pulmonary disease from a random population sample: findings from the Copenhagen City Heart Study
    • 54 Vestbo, J, Prescott, E, Almdal, T, et al. Body mass, fat-free body mass, and prognosis in patients with chronic obstructive pulmonary disease from a random population sample: findings from the Copenhagen City Heart Study. Am J Respir Crit Care Med 173 (2006), 79–83.
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 79-83
    • Vestbo, J.1    Prescott, E.2    Almdal, T.3
  • 55
    • 84897482116 scopus 로고    scopus 로고
    • Effects of anabolic steroids on chronic obstructive pulmonary disease: a meta-analysis of randomised controlled trials
    • 55 Pan, L, Wang, M, Xie, X, Du, C, Guo, Y, Effects of anabolic steroids on chronic obstructive pulmonary disease: a meta-analysis of randomised controlled trials. PLoS One, 9, 2014, e84855.
    • (2014) PLoS One , vol.9 , pp. e84855
    • Pan, L.1    Wang, M.2    Xie, X.3    Du, C.4    Guo, Y.5
  • 56
    • 5144228345 scopus 로고    scopus 로고
    • Effects of testosterone and resistance training in men with chronic obstructive pulmonary disease
    • 56 Casaburi, R, Bhasin, S, Cosentino, L, et al. Effects of testosterone and resistance training in men with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 170 (2004), 870–878.
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 870-878
    • Casaburi, R.1    Bhasin, S.2    Cosentino, L.3
  • 57
    • 80052053931 scopus 로고    scopus 로고
    • Obesity and COPD: associated symptoms, health-related quality of life, and medication use
    • 57 Cecere, LM, Littman, AJ, Slatore, CG, et al. Obesity and COPD: associated symptoms, health-related quality of life, and medication use. COPD 8 (2011), 275–284.
    • (2011) COPD , vol.8 , pp. 275-284
    • Cecere, L.M.1    Littman, A.J.2    Slatore, C.G.3
  • 58
    • 79959196640 scopus 로고    scopus 로고
    • Physiologic responses during the six minute walk test in obese and non-obese COPD patients
    • 58 Bautista, J, Ehsan, M, Normandin, E, Zuwallack, R, Lahiri, B, Physiologic responses during the six minute walk test in obese and non-obese COPD patients. Respir Med 105 (2011), 1189–1194.
    • (2011) Respir Med , vol.105 , pp. 1189-1194
    • Bautista, J.1    Ehsan, M.2    Normandin, E.3    Zuwallack, R.4    Lahiri, B.5
  • 59
    • 84949818269 scopus 로고    scopus 로고
    • Effects of obesity on weight-bearing versus weight-supported exercise testing in patients with COPD
    • 59 Maatman, RC, Spruit, MA, van Melick, PP, et al. Effects of obesity on weight-bearing versus weight-supported exercise testing in patients with COPD. Respirology 21 (2016), 483–488.
    • (2016) Respirology , vol.21 , pp. 483-488
    • Maatman, R.C.1    Spruit, M.A.2    van Melick, P.P.3
  • 60
    • 79960278594 scopus 로고    scopus 로고
    • Effects of body mass index on static lung volumes in patients with airway obstruction
    • 60 O'Donnell, DE, Deesomchok, A, Lam, YM, et al. Effects of body mass index on static lung volumes in patients with airway obstruction. Chest 140 (2011), 461–468.
    • (2011) Chest , vol.140 , pp. 461-468
    • O'Donnell, D.E.1    Deesomchok, A.2    Lam, Y.M.3
  • 61
    • 0033453187 scopus 로고    scopus 로고
    • Prognostic value of nutritional status in chronic obstructive pulmonary disease
    • 61 Landbo, C, Prescott, E, Lange, P, Vestbo, J, Almdal, TP, Prognostic value of nutritional status in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 160 (1999), 1856–1861.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1856-1861
    • Landbo, C.1    Prescott, E.2    Lange, P.3    Vestbo, J.4    Almdal, T.P.5
  • 62
    • 84862100999 scopus 로고    scopus 로고
    • Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype
    • 62 Agustí, A, Edwards, LD, Rennard, SI, et al., the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators. Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. PLoS One, 7, 2012, e37483.
    • (2012) PLoS One , vol.7 , pp. e37483
    • Agustí, A.1    Edwards, L.D.2    Rennard, S.I.3
  • 63
    • 84902240469 scopus 로고    scopus 로고
    • A possible link between increased metabolic activity of fat tissue and aortic wall inflammation in subjects with COPD. A retrospective 18F-FDG-PET/CT pilot study
    • 63 Vanfleteren, LE, van Meerendonk, AM, Franssen, FM, et al. A possible link between increased metabolic activity of fat tissue and aortic wall inflammation in subjects with COPD. A retrospective 18F-FDG-PET/CT pilot study. Respir Med 108 (2014), 883–890.
    • (2014) Respir Med , vol.108 , pp. 883-890
    • Vanfleteren, L.E.1    van Meerendonk, A.M.2    Franssen, F.M.3
  • 64
    • 78049381527 scopus 로고    scopus 로고
    • The impact of obesity on walking and cycling performance and response to pulmonary rehabilitation in COPD
    • 64 Sava, F, Laviolette, L, Bernard, S, Breton, MJ, Bourbeau, J, Maltais, F, The impact of obesity on walking and cycling performance and response to pulmonary rehabilitation in COPD. BMC Pulm Med, 10, 2010, 55.
    • (2010) BMC Pulm Med , vol.10 , pp. 55
    • Sava, F.1    Laviolette, L.2    Bernard, S.3    Breton, M.J.4    Bourbeau, J.5    Maltais, F.6
  • 65
    • 84878810021 scopus 로고    scopus 로고
    • Water-based exercise in COPD with physical comorbidities: a randomised controlled trial
    • 65 McNamara, RJ, McKeough, ZJ, McKenzie, DK, Alison, JA, Water-based exercise in COPD with physical comorbidities: a randomised controlled trial. Eur Respir J 41 (2013), 1284–1291.
    • (2013) Eur Respir J , vol.41 , pp. 1284-1291
    • McNamara, R.J.1    McKeough, Z.J.2    McKenzie, D.K.3    Alison, J.A.4
  • 66
    • 84886418056 scopus 로고    scopus 로고
    • An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation
    • 66 Spruit, MA, Singh, SJ, Garvey, C, et al., the ATS/ERS Task Force on Pulmonary Rehabilitation. An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med 188 (2013), e13–e64.
    • (2013) Am J Respir Crit Care Med , vol.188 , pp. e13-e64
    • Spruit, M.A.1    Singh, S.J.2    Garvey, C.3
  • 67
    • 84899792562 scopus 로고    scopus 로고
    • Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease
    • CD002309
    • 67 Chong, J, Leung, B, Poole, P, Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease. Cochrane Database Syst Rev, 11, 2013 CD002309.
    • (2013) Cochrane Database Syst Rev , vol.11
    • Chong, J.1    Leung, B.2    Poole, P.3
  • 69
    • 47349093933 scopus 로고    scopus 로고
    • The recognition and treatment of vertebral fractures in males with chronic obstructive pulmonary disease
    • 69 Carter, JD, Patel, S, Sultan, FL, et al. The recognition and treatment of vertebral fractures in males with chronic obstructive pulmonary disease. Respir Med 102 (2008), 1165–1172.
    • (2008) Respir Med , vol.102 , pp. 1165-1172
    • Carter, J.D.1    Patel, S.2    Sultan, F.L.3
  • 70
    • 77950659884 scopus 로고    scopus 로고
    • Epidemiology of rib fractures in older men: Osteoporotic Fractures in Men (MrOS) prospective cohort study
    • 70 Barrett-Connor, E, Nielson, CM, Orwoll, E, Bauer, DC, Cauley, JA, the Osteoporotic Fractures in Men Study Group. Epidemiology of rib fractures in older men: Osteoporotic Fractures in Men (MrOS) prospective cohort study. BMJ, 340, 2010, c1069.
    • (2010) BMJ , vol.340 , pp. c1069
    • Barrett-Connor, E.1    Nielson, C.M.2    Orwoll, E.3    Bauer, D.C.4    Cauley, J.A.5
  • 71
    • 84874073121 scopus 로고    scopus 로고
    • Improving hip fractures outcomes for COPD patients
    • 71 Regan, EA, Radcliff, TA, Henderson, WG, et al. Improving hip fractures outcomes for COPD patients. COPD 10 (2013), 11–19.
    • (2013) COPD , vol.10 , pp. 11-19
    • Regan, E.A.1    Radcliff, T.A.2    Henderson, W.G.3
  • 72
    • 79952210375 scopus 로고    scopus 로고
    • COPD, bone metabolism, and osteoporosis
    • 72 Lehouck, A, Boonen, S, Decramer, M, Janssens, W, COPD, bone metabolism, and osteoporosis. Chest 139 (2011), 648–657.
    • (2011) Chest , vol.139 , pp. 648-657
    • Lehouck, A.1    Boonen, S.2    Decramer, M.3    Janssens, W.4
  • 73
    • 84857443673 scopus 로고    scopus 로고
    • Richtlijn Osteoporose en Fractuurpreventie derde herziening
    • (accessed April 26, 2016; in Dutch).
    • 73 Richtlijn Osteoporose en Fractuurpreventie derde herziening. www.diliguide.nl/document/1015, 2011 (accessed April 26, 2016; in Dutch).
    • (2011)
  • 74
    • 84881171452 scopus 로고    scopus 로고
    • Vitamin D in the prevention of acute respiratory infection: systematic review of clinical studies
    • 74 Jolliffe, DA, Griffiths, CJ, Martineau, AR, Vitamin D in the prevention of acute respiratory infection: systematic review of clinical studies. J Steroid Biochem Mol Biol 136 (2013), 321–329.
    • (2013) J Steroid Biochem Mol Biol , vol.136 , pp. 321-329
    • Jolliffe, D.A.1    Griffiths, C.J.2    Martineau, A.R.3
  • 75
    • 84897144931 scopus 로고    scopus 로고
    • Vitamin D status and chronic obstructive pulmonary disease: a prospective general population study
    • 75 Skaaby, T, Husemoen, LL, Thuesen, BH, et al. Vitamin D status and chronic obstructive pulmonary disease: a prospective general population study. PLoS One, 9, 2014, e90654.
    • (2014) PLoS One , vol.9 , pp. e90654
    • Skaaby, T.1    Husemoen, L.L.2    Thuesen, B.H.3
  • 76
    • 84855832483 scopus 로고    scopus 로고
    • High doses of vitamin D to reduce exacerbations in chronic obstructive pulmonary disease: a randomized trial
    • 76 Lehouck, A, Mathieu, C, Carremans, C, et al. High doses of vitamin D to reduce exacerbations in chronic obstructive pulmonary disease: a randomized trial. Ann Intern Med 156 (2012), 105–114.
    • (2012) Ann Intern Med , vol.156 , pp. 105-114
    • Lehouck, A.1    Mathieu, C.2    Carremans, C.3
  • 77
    • 84922021820 scopus 로고    scopus 로고
    • Vitamin D3 supplementation in patients with chronic obstructive pulmonary disease (ViDiCO): a multicentre, double-blind, randomised controlled trial
    • 77 Martineau, AR, James, WY, Hooper, RL, et al. Vitamin D3 supplementation in patients with chronic obstructive pulmonary disease (ViDiCO): a multicentre, double-blind, randomised controlled trial. Lancet Respir Med 3 (2015), 120–130.
    • (2015) Lancet Respir Med , vol.3 , pp. 120-130
    • Martineau, A.R.1    James, W.Y.2    Hooper, R.L.3
  • 78
    • 3042646346 scopus 로고    scopus 로고
    • Increased gastro-oesophageal reflux disease in patients with severe COPD
    • 78 Casanova, C, Baudet, JS, del Valle Velasco, M, et al. Increased gastro-oesophageal reflux disease in patients with severe COPD. Eur Respir J 23 (2004), 841–845.
    • (2004) Eur Respir J , vol.23 , pp. 841-845
    • Casanova, C.1    Baudet, J.S.2    del Valle Velasco, M.3
  • 79
    • 33750065102 scopus 로고    scopus 로고
    • Role of gastroesophageal reflux symptoms in exacerbations of COPD
    • 79 Rascon-Aguilar, IE, Pamer, M, Wludyka, P, et al. Role of gastroesophageal reflux symptoms in exacerbations of COPD. Chest 130 (2006), 1096–1101.
    • (2006) Chest , vol.130 , pp. 1096-1101
    • Rascon-Aguilar, I.E.1    Pamer, M.2    Wludyka, P.3
  • 80
    • 77956689733 scopus 로고    scopus 로고
    • Susceptibility to exacerbation in chronic obstructive pulmonary disease
    • 80 Hurst, JR, Vestbo, J, Anzueto, A, et al., the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators. Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med 363 (2010), 1128–1138.
    • (2010) N Engl J Med , vol.363 , pp. 1128-1138
    • Hurst, J.R.1    Vestbo, J.2    Anzueto, A.3
  • 81
    • 0034790915 scopus 로고    scopus 로고
    • The effects of an inhaled beta(2)-adrenergic agonist on lower esophageal function: a dose-response study
    • 81 Crowell, MD, Zayat, EN, Lacy, BE, Schettler-Duncan, A, Liu, MC, The effects of an inhaled beta(2)-adrenergic agonist on lower esophageal function: a dose-response study. Chest 120 (2001), 1184–1189.
    • (2001) Chest , vol.120 , pp. 1184-1189
    • Crowell, M.D.1    Zayat, E.N.2    Lacy, B.E.3    Schettler-Duncan, A.4    Liu, M.C.5
  • 82
    • 68149152912 scopus 로고    scopus 로고
    • A randomized, single-blind study of lansoprazole for the prevention of exacerbations of chronic obstructive pulmonary disease in older patients
    • 82 Sasaki, T, Nakayama, K, Yasuda, H, et al. A randomized, single-blind study of lansoprazole for the prevention of exacerbations of chronic obstructive pulmonary disease in older patients. J Am Geriatr Soc 57 (2009), 1453–1457.
    • (2009) J Am Geriatr Soc , vol.57 , pp. 1453-1457
    • Sasaki, T.1    Nakayama, K.2    Yasuda, H.3
  • 83
    • 33646853281 scopus 로고    scopus 로고
    • Beyond gastric acid reduction: proton pump inhibitors induce heme oxygenase-1 in gastric and endothelial cells
    • 83 Becker, JC, Grosser, N, Waltke, C, et al. Beyond gastric acid reduction: proton pump inhibitors induce heme oxygenase-1 in gastric and endothelial cells. Biochem Biophys Res Commun 345 (2006), 1014–1021.
    • (2006) Biochem Biophys Res Commun , vol.345 , pp. 1014-1021
    • Becker, J.C.1    Grosser, N.2    Waltke, C.3
  • 84
    • 41149100007 scopus 로고    scopus 로고
    • Mental disorders in chronic obstructive pulmonary disease (COPD)
    • 84 Vögele, C, von Leupoldt, A, Mental disorders in chronic obstructive pulmonary disease (COPD). Respir Med 102 (2008), 764–773.
    • (2008) Respir Med , vol.102 , pp. 764-773
    • Vögele, C.1    von Leupoldt, A.2
  • 86
    • 77955123938 scopus 로고    scopus 로고
    • The effectiveness of a group cognitive-behavioural breathlessness intervention on health status, mood and hospital admissions in elderly patients with chronic obstructive pulmonary disease
    • 86 Howard, C, Dupont, S, Haselden, B, Lynch, J, Wills, P, The effectiveness of a group cognitive-behavioural breathlessness intervention on health status, mood and hospital admissions in elderly patients with chronic obstructive pulmonary disease. Psychol Health Med 15 (2010), 371–385.
    • (2010) Psychol Health Med , vol.15 , pp. 371-385
    • Howard, C.1    Dupont, S.2    Haselden, B.3    Lynch, J.4    Wills, P.5
  • 87
    • 0036845470 scopus 로고    scopus 로고
    • A systematic review of the use of opioids in the management of dyspnoea
    • 87 Jennings, AL, Davies, AN, Higgins, JP, Gibbs, JS, Broadley, KE, A systematic review of the use of opioids in the management of dyspnoea. Thorax 57 (2002), 939–944.
    • (2002) Thorax , vol.57 , pp. 939-944
    • Jennings, A.L.1    Davies, A.N.2    Higgins, J.P.3    Gibbs, J.S.4    Broadley, K.E.5
  • 88
    • 84893320092 scopus 로고    scopus 로고
    • Safety of benzodiazepines and opioids in very severe respiratory disease: national prospective study
    • 88 Ekström, MP, Bornefalk-Hermansson, A, Abernethy, AP, Currow, DC, Safety of benzodiazepines and opioids in very severe respiratory disease: national prospective study. BMJ, 348, 2014, g445.
    • (2014) BMJ , vol.348 , pp. g445
    • Ekström, M.P.1    Bornefalk-Hermansson, A.2    Abernethy, A.P.3    Currow, D.C.4
  • 89
    • 84907301768 scopus 로고    scopus 로고
    • Depression and suicidality in COPD: understandable reaction or independent disorders?
    • 89 Hegerl, U, Mergl, R, Depression and suicidality in COPD: understandable reaction or independent disorders?. Eur Respir J 44 (2014), 734–743.
    • (2014) Eur Respir J , vol.44 , pp. 734-743
    • Hegerl, U.1    Mergl, R.2
  • 90
    • 0020527558 scopus 로고
    • The hospital anxiety and depression scale
    • 90 Zigmond, AS, Snaith, RP, The hospital anxiety and depression scale. Acta Psychiatr Scand 67 (1983), 361–370.
    • (1983) Acta Psychiatr Scand , vol.67 , pp. 361-370
    • Zigmond, A.S.1    Snaith, R.P.2
  • 91
    • 84942635666 scopus 로고    scopus 로고
    • Differential response to pulmonary rehabilitation in COPD: multidimensional profiling
    • 91 Spruit, MA, Augustin, IM, Vanfleteren, LE, et al., the CIRO+ Rehabilitation Network. Differential response to pulmonary rehabilitation in COPD: multidimensional profiling. Eur Respir J 46 (2015), 1625–1635.
    • (2015) Eur Respir J , vol.46 , pp. 1625-1635
    • Spruit, M.A.1    Augustin, I.M.2    Vanfleteren, L.E.3
  • 92
    • 80051869611 scopus 로고    scopus 로고
    • Effects of medical and psychological treatment of depression in patients with COPD—a review
    • 92 Fritzsche, A, Clamor, A, von Leupoldt, A, Effects of medical and psychological treatment of depression in patients with COPD—a review. Respir Med 105 (2011), 1422–1433.
    • (2011) Respir Med , vol.105 , pp. 1422-1433
    • Fritzsche, A.1    Clamor, A.2    von Leupoldt, A.3
  • 93
    • 27644466207 scopus 로고    scopus 로고
    • Efficacy of bupropion and nortriptyline for smoking cessation among people at risk for or with chronic obstructive pulmonary disease
    • 93 Wagena, EJ, Knipschild, PG, Huibers, MJ, Wouters, EF, van Schayck, CP, Efficacy of bupropion and nortriptyline for smoking cessation among people at risk for or with chronic obstructive pulmonary disease. Arch Intern Med 165 (2005), 2286–2292.
    • (2005) Arch Intern Med , vol.165 , pp. 2286-2292
    • Wagena, E.J.1    Knipschild, P.G.2    Huibers, M.J.3    Wouters, E.F.4    van Schayck, C.P.5
  • 95
    • 84938877972 scopus 로고    scopus 로고
    • Objectively identified comorbidities in chronic obstructive pulmonary disease: impact on pulmonary rehabilitation outcomes
    • 95 Mesquita, R, Vanfleteren, LE, Franssen, FM, et al. Objectively identified comorbidities in chronic obstructive pulmonary disease: impact on pulmonary rehabilitation outcomes. Eur Respir J 46 (2015), 545–548.
    • (2015) Eur Respir J , vol.46 , pp. 545-548
    • Mesquita, R.1    Vanfleteren, L.E.2    Franssen, F.M.3
  • 97
    • 2942720459 scopus 로고    scopus 로고
    • Effects of whole-body exercise training on body composition and functional capacity in normal-weight patients with COPD
    • 97 Franssen, FM, Broekhuizen, R, Janssen, PP, Wouters, EF, Schols, AM, Effects of whole-body exercise training on body composition and functional capacity in normal-weight patients with COPD. Chest 125 (2004), 2021–2028.
    • (2004) Chest , vol.125 , pp. 2021-2028
    • Franssen, F.M.1    Broekhuizen, R.2    Janssen, P.P.3    Wouters, E.F.4    Schols, A.M.5
  • 98
    • 84899860065 scopus 로고    scopus 로고
    • Arterial stiffness in patients with COPD: the role of systemic inflammation and the effects of pulmonary rehabilitation
    • 98 Vanfleteren, LE, Spruit, MA, Groenen, MT, et al. Arterial stiffness in patients with COPD: the role of systemic inflammation and the effects of pulmonary rehabilitation. Eur Respir J 43 (2014), 1306–1315.
    • (2014) Eur Respir J , vol.43 , pp. 1306-1315
    • Vanfleteren, L.E.1    Spruit, M.A.2    Groenen, M.T.3
  • 100
    • 84905964581 scopus 로고    scopus 로고
    • The path to personalised medicine in COPD
    • 100 Agusti, A, The path to personalised medicine in COPD. Thorax 69 (2014), 857–864.
    • (2014) Thorax , vol.69 , pp. 857-864
    • Agusti, A.1
  • 101
    • 84916234213 scopus 로고    scopus 로고
    • Nutritional assessment and therapy in COPD: a European Respiratory Society statement
    • 101 Schols, AM, Ferreira, IM, Franssen, FM, et al. Nutritional assessment and therapy in COPD: a European Respiratory Society statement. Eur Respir J 44 (2014), 1504–1520.
    • (2014) Eur Respir J , vol.44 , pp. 1504-1520
    • Schols, A.M.1    Ferreira, I.M.2    Franssen, F.M.3
  • 102
    • 79954994400 scopus 로고    scopus 로고
    • Identification and prospective validation of clinically relevant chronic obstructive pulmonary disease (COPD) subtypes
    • 102 Garcia-Aymerich, J, Gómez, FP, Benet, M, et al., the PAC-COPD Study Group. Identification and prospective validation of clinically relevant chronic obstructive pulmonary disease (COPD) subtypes. Thorax 66 (2011), 430–437.
    • (2011) Thorax , vol.66 , pp. 430-437
    • Garcia-Aymerich, J.1    Gómez, F.P.2    Benet, M.3
  • 103
    • 79953293141 scopus 로고    scopus 로고
    • Radiographic emphysema predicts low bone mineral density in a tobacco-exposed cohort
    • 103 Bon, J, Fuhrman, CR, Weissfeld, JL, et al. Radiographic emphysema predicts low bone mineral density in a tobacco-exposed cohort. Am J Respir Crit Care Med 183 (2011), 885–890.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 885-890
    • Bon, J.1    Fuhrman, C.R.2    Weissfeld, J.L.3
  • 104
    • 79551505136 scopus 로고    scopus 로고
    • Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome
    • 104 Lötvall, J, Akdis, CA, Bacharier, LB, et al. Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome. J Allergy Clin Immunol 127 (2011), 355–360.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 355-360
    • Lötvall, J.1    Akdis, C.A.2    Bacharier, L.B.3


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