Clinical and radiologic disease in smokers with normal spirometry

JAMA Internal Medicine

Volumn 175, Issue 9, 2015, Pages 1539-1549

  Regan, Elizabeth A ^a,b   Lynch, David A ^a   Curran Everett, Douglas ^a   Curtis, Jeffrey L ^c,d   Austin, John H M ^e   Grenier, Philippe A ^f   Kauczor, Hans Ulrich ^g   Bailey, William C ^h   De Meo, Dawn L ⁱ   Casaburi, Richard H ^j   Friedman, Paul ^k   Van Beek, Edwin J R ^l   Hokanson, John E ^b   Bowler, Russell P ^a   Beaty, Terri H ^m   Washko, George R ⁱ   Han, Meilan K ^d   Kim, Victor ⁿ   Kim, Song Soo ^o   Yagihashi, Kunihiro ^p   Washington, Lacey ^q   McEvoy, Charlene E ^r   Tanner, Clint ^a   Mannino, David M ^s   Make, Barry J ^a   Silverman, Edwin K ⁱ   Crapo, James D ^a   Martinez, Carlos ^t   Pernicano, Perry G ^t   Hanania, Nicola ^u   Alapat, Philip ^u   Bandi, Venkata ^u   Atik, Mustafa ^u   Boriek, Aladin ^u   Guntupalli, Kalpatha ^u   Guy, Elizabeth ^u   Parulekar, Amit ^u   Nachiappan, Arun ^u   Hersh, Craig ^v   Jacobson, Francine ^v   Barr, R Graham ^w   Thomashow, Byron ^w   D'Souza, Belinda ^w   Pearson, Gregory D N ^w   Rozenshtein, Anna ^w   MacIntyre, Neil ^q   McAdams, H Page ^q   Tashjian, Joseph ^x   Wise, Robert ^y   Hansel, Nadia ^y   Brown, Robert ^y   Horton, Karen ^y   Putcha, Nirupama ^y   Adami, Alessandra ^z   Porszasz, Janos ^z   Fischer, Hans ^z   Budoff, Matthew ^z   Cannon, Dan ^z   Rossiter, Harry ^z   Sharafkhaneh, Amir ^aa   Lan, Charlie ^aa   Wendt, Christine ^ab   Bell, Brian ^ab   Foreman, Marilyn ^ac   Westney, Gloria ^ac   Berkowitz, Eugene ^ac   Rosiello, Richard ^ad   Pace, David ^ad   Criner, Gerard ^ae   Ciccolella, David ^ae   Cordova, Francis ^ae   Dass, Chandra ^ae   D'Alonzo, Robert ^ae   Desai, Parag ^ae   Jacobs, Michael ^ae   Kelsen, Steven ^ae   Mamary, A James ^ae   Marchetti, Nathaniel ^ae   Satti, Aditti ^ae   Shenoy, Kartik ^a   Steiner, Robert M ^ae   Swift, Alex ^ae   Swift, Irene ^ae   Vega Sanchez, Gloria ^ae   Dransfield, Mark ^h   Wells, J Michael ^h   Bhatt, Surya ^h   Nath, Hrudaya ^h   Ramsdell, Joe ^k   Soler, Xavier ^k   Yen, Andrew ^k   Cornellas, Alejandro ^af   Newell, John ^af   Thompson, Brad ^af   Kazerooni, Ella ^ag   Martinez, Fernando ^ag   Billings, Joanne ^ah   Allen, Tadashi ^ah   Sciurba, Frank ^ai   Chandra, Divay ^ai   Weissfeld, Joel ^ai   Fuhrman, Carl ^ai   Bon, Jessica ^ai   Anzueto, Antonio ^aj   Adams, Sandra ^aj   Maselli Caceres, Diego ^aj   Ruiz, Mario E ^aj   more..

^a DEPARTMENT OF MEDICINE   (United States)

^b Department of Civil and Environmental Engineering at Colorado State University and the Department of Environmental and Occupational Health at the Colorado School of Public Health   (United States)

^c VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e New York Presbyterian Morgan Stanley Children's Hospital   (United States)

^f PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^g UNIVERSITY OF HEIDELBERG   (Germany)

^h UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

ⁱ HARVARD MEDICAL SCHOOL   (United States)

^j HARBOR UCLA MEDICAL CENTER   (United States)

^k UNIVERSITY OF CALIFORNIA   (United States)

^l UNIVERSITY OF EDINBURGH   (United Kingdom)

^m JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

ⁿ TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^o Chungnam National University College of Medicine   (South Korea)

^p ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^q DUKE UNIVERSITY MEDICAL CENTER   (United States)

^r HEALTHPARTNERS INSTITUTE   (United States)

^s UNIVERSITY OF KENTUCKY COLLEGE OF PUBLIC HEALTH   (United States)

^t Ann Arbor MI VA GRECC   (United States)

^u BAYLOR COLLEGE OF MEDICINE   (United States)

^v BRIGHAM AND WOMEN S HOSPITAL   (United States)

^w Howard Hughes Medical Institute   (United States)

^x HEALTHPARTNERS RESEARCH FOUNDATION   (United States)

^y JOHNS HOPKINS UNIVERSITY   (United States)

^z UCLA MEDICAL CENTER   (United States)

^aa MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

^ab Morehouse School of Medicine ^*  (United States)

^ac MOREHOUSE SCHOOL OF MEDICINE   (United States)

^ad Reliant Medical Group Inc   (United States)

^ae TEMPLE UNIVERSITY   (United States)

^af UNIVERSITY OF IOWA   (United States)

^ag UNIVERSITY OF MICHIGAN   (United States)

^ah UNIVERSITY OF MINNESOTA   (United States)

^ai UNIVERSITY OF PITTSBURGH   (United States)

^aj UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CHOLINERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID;

ADULT; AGE; ARTICLE; CHRONIC BRONCHITIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; COHORT ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; DRUG USE; EMPHYSEMA; EXERCISE TOLERANCE; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; LUNG DISEASE; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; QUALITY OF LIFE; QUESTIONNAIRE; RADIODIAGNOSIS; RESPIRATORY TRACT DISEASE; SMOKING; SMOKING CESSATION; SPIROMETRY; ST. GEORGE RESPIRATORY QUESTIONNAIRE; UNITED STATES; WALKING; ADVERSE EFFECTS; AGED; CASE CONTROL STUDY; CLINICAL TRIAL; MIDDLE AGED; MULTICENTER STUDY; NUTRITION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RADIOGRAPHY; THORAX RADIOGRAPHY;

AGED; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; EXERCISE TOLERANCE; FEMALE; HUMANS; MALE; MIDDLE AGED; NUTRITION SURVEYS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; QUALITY OF LIFE; RADIOGRAPHY, THORACIC; SMOKING; SPIROMETRY; TOMOGRAPHY, X-RAY COMPUTED; UNITED STATES;

EID: 84941247915     PISSN: 21686106     EISSN: 21686114     Source Type: Journal    
DOI: 10.1001/jamainternmed.2015.2735     Document Type: Article

References (33)

1. Tomar SL, Asma S. Smoking-attributable periodontitis in the United States: findings from NHANES III: National Health and Nutrition Examination Survey. J Periodontol. 2000;71(5):743-751.
2. Behavioral Risk Factor Surveillance System. Smoking exposures in the United States. 2013. http://www.cdc.gov/brfss/annual-data/annual-data.htm. Accessed May 15, 2015.
3. Xu JQ, Kochanek KD, Murphy SL, Tejada-Vera B. Deaths: Final Data for 2007. Hyattsville, MD: National Center for Health Statistics; 2010. National Vital Statistics Reports. http://www.cdc.gov/nchs/data/nvsr/nvsr58/nvsr58-19.pdf. Accessed May 11, 2015.
4. The 2004 United States Surgeon General's report: the health consequences of smoking. NSW Public Health Bull. 2004;15(5-6):107.
5. National Center for Chronic Disease Prevention and Health Promotion (US) Office on Smoking and Health. The Health Consequences of Smoking: 50 Years of Progress: A Report of the Surgeon General. Atlanta, GA: Centers for Disease Control and Prevention; 2014.
6. Lundbäck B, Lindberg A, Lindström M, et al; Obstructive Lung Disease in Northern Sweden Studies. Not 15 but 50% of smokers develop COPD? report from the Obstructive Lung Disease in Northern Sweden Studies. Respir Med. 2003;97(2):115-122.
7. Lindberg A, Bjerg A, Rönmark E, Larsson LG, Lundbäck B. Prevalence and underdiagnosis of COPD by disease severity and the attributable fraction of smoking: report from the Obstructive Lung Disease in Northern Sweden Studies. Respir Med. 2006;100(2):264-272.
8. Vehmas T, Kivisaari L, Huuskonen MS, Jaakkola MS. Effects of tobacco smoking on findings in chest computed tomography among asbestos-exposed workers. Eur Respir J. 2003;21(5):866-871.
9. Tylén U, Boijsen M, Ekberg-Jansson A, Bake B, Löfdahl CG. Emphysematous lesions and lung function in healthy smokers 60 years of age. Respir Med. 2000;94(1):38-43.
10. Mohamed Hoesein FA, De Hoop B, Zanen P, et al. CT-quantified emphysema in male heavy smokers: association with lung function decline. Thorax. 2011;66(9):782-787.
11. Fletcher C, Peto R. The natural history of chronic airflow obstruction. Br Med J. 1977;1(6077):1645-1648.
12. Vestbo J, Prescott E, Lange P; Copenhagen City Heart Study Group. Association of chronic mucus hypersecretion with FEV1 decline and chronic obstructive pulmonary disease morbidity. Am J Respir Crit Care Med. 1996;153(5):1530-1535.
13. Sandvik L, Erikssen G, Thaulow E. Long term effects of smoking on physical fitness and lung function: a longitudinal study of 1393 middle aged Norwegian men for seven years. BMJ. 1995;311(7007):715-718.
14. Jaakkola MS, Ernst P, Jaakkola JJ, N'gan'ga LW, Becklake MR. Effect of cigarette smoking on evolution of ventilatory lung function in young adults: an eight year longitudinal study. Thorax. 1991;46(12):907-913.
15. Niewoehner DE, Kleinerman J, Rice DB. Pathologic changes in the peripheral airways of young cigarette smokers. N Engl J Med. 1974;291(15):755-758.
16. Burrows B. An overview of obstructive lung diseases. Med Clin North Am. 1981;65(3):455-471.
17. Rabe KF, Hurd S, Anzueto A, et al; Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2007;176(6):532-555.
18. Regan EA, Hokanson JE, Murphy JR, et al. Genetic epidemiology of COPD (COPDGene) study design. COPD. 2010;7(1):32-43.
19. Schroeder JD, McKenzie AS, Zach JA, et al. Relationships between airflow obstruction and quantitative CT measurements of emphysema, air trapping, and airways in subjects with and without chronic obstructive pulmonary disease. AJR Am J Roentgenol. 2013;201(3):W460-W470.
20. Kim SS, Yagihashi K, Stinson DS, et al. Visual assessment of CT findings in smokers with nonobstructed spirometric abnormalities in the COPDGene study. Chronic Obstr Pulm Dis (Miami). 2014;1(1):88-96.
21. Mahler DA, Wells CK. Evaluation of clinical methods for rating dyspnea. Chest. 1988;93(3):580-586.
22. Jones PW, Tabberer M, Chen WH. Creating scenarios of the impact of COPD and their relationship to COPD Assessment Test (CAT) scores. BMC Pulm Med. 2011;11:42.
23. Wan ES, Castaldi PJ, Cho MH, et al; COPDGene Investigators. Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene. Respir Res. 2014;15(1):89.
24. Wan ES, Hokanson JE, Murphy JR, et al; COPDGene Investigators. Clinical and radiographic predictors of GOLD-unclassified smokers in the COPDGene study. Am J Respir Crit Care Med. 2011;184(1):57-63.
25. Barr RG, Berkowitz EA, Bigazzi F, et al; COPDGene CT Workshop Group. A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation. COPD. 2012;9(2):151-159.
26. Remy-Jardin M, Remy J, Boulenguez C, Sobaszek A, Edme JL, Furon D. Morphologic effects of cigarette smoking on airways and pulmonary parenchyma in healthy adult volunteers: CT evaluation and correlation with pulmonary function tests. Radiology. 1993;186(1):107-115.
27. Mohamed Hoesein FA, Schmidt M, Mets OM, et al. Discriminating dominant computed tomography phenotypes in smokers without or with mild COPD. Respir Med. 2014;108(1):136-143.
28. Kohansal R, Martinez-Camblor P, Agustí A, Buist AS, Mannino DM, Soriano JB. The natural history of chronic airflow obstruction revisited: an analysis of the Framingham Offspring cohort. Am J Respir Crit Care Med. 2009;180(1):3-10.
29. Vestbo J, Hurd SS, Agustí AG, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2013;187(4):347-365.
30. Scadding JG. Principles of definition in medicine with special reference to chronic bronchitis and emphysema. Lancet. 1959;1(7068):323-325.
31. Snider GL. Nosology for our day: its application to chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2003;167(5):678-683.
32. U. S. Census Bureau, Statistical Abstract of the United States: 2012. Table 7: resident population by sex and age: 1980 to 2010. http://www.census.gov/compendia/statab/2012/tables/12s0007.pdf. Accessed July 12, 2013.
33. Maltais F, Dennis N, Chan CK. Rationale for earlier treatment in COPD: a systematic review of published literature in mild-to-moderate COPD. COPD. 2013;10(1):79-103.