-
1
-
-
84884286748
-
Sensitization via healthy skin programs th2 responses in individuals with atopic dermatitis
-
Newell, L., et al. Sensitization via Healthy Skin Programs Th2 Responses in Individuals with Atopic Dermatitis. J Invest Dermatol 133, 2372-2380, doi:10.1038/jid.2013.148 (2013).
-
(2013)
J Invest Dermatol
, vol.133
, pp. 2372-2380
-
-
Newell, L.1
-
2
-
-
84894033804
-
Distinct molecular signature of human skin langerhans cells denotes critical differences in cutaneous dendritic cell immune regulation
-
Polak, M. E., et al. Distinct molecular signature of human skin langerhans cells denotes critical differences in cutaneous dendritic cell immune regulation. J Invest Dermatol 134, 695-703, doi:10.1038/jid.2013.375 (2014).
-
(2014)
J Invest Dermatol
, vol.134
, pp. 695-703
-
-
Polak, M.E.1
-
3
-
-
84861196667
-
CD70-CD27 interaction augments CD8+ T-cell activation by human epidermal Langerhans cells
-
Polak, M. E., et al. CD70-CD27 interaction augments CD8+ T-cell activation by human epidermal Langerhans cells. J Invest Dermatol 132, 1636-1644, doi:10.1038/jid.2012.26 (2012).
-
(2012)
J Invest Dermatol
, vol.132
, pp. 1636-1644
-
-
Polak, M.E.1
-
4
-
-
84861462335
-
Human epidermal Langerhans cells maintain immune homeostasis in skin by activating skin resident regulatory T cells
-
Seneschal, J., Clark, R. A., Gehad, A., Baecher-Allan, C. M., Kupper, T. S. Human epidermal Langerhans cells maintain immune homeostasis in skin by activating skin resident regulatory T cells. Immunity 36, 873-884, doi:10.1016/j.immuni.2012.03.018 (2012).
-
(2012)
Immunity
, vol.36
, pp. 873-884
-
-
Seneschal, J.1
Clark, R.A.2
Gehad, A.3
Baecher-Allan, C.M.4
Kupper, T.S.5
-
5
-
-
84876692378
-
Langerhans cells favor skin flora tolerance through limited presentation of bacterial antigens and induction of regulatory T cells
-
van der Aar, A. M., et al. Langerhans Cells Favor Skin Flora Tolerance through Limited Presentation of Bacterial Antigens and Induction of Regulatory T Cells. J Invest Dermatol 133, 1240-1249, doi:10.1038/jid.2012.500 (2013).
-
(2013)
J Invest Dermatol
, vol.133
, pp. 1240-1249
-
-
Vander Aar, A.M.1
-
6
-
-
67651211687
-
Phenotype of atopic dermatitis subjects with a history of eczema herpeticum
-
269 e261-267
-
Beck, L. A., et al. Phenotype of atopic dermatitis subjects with a history of eczema herpeticum. J Allergy Clin Immunol 124, 260-269, 269 e261-267, doi:10.1016/j.jaci.2009.05.020 (2009).
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 260-269
-
-
Beck, L.A.1
-
7
-
-
34247178557
-
Risk factors of atopic dermatitis patients for eczema herpeticum
-
Peng, W. M., et al. Risk factors of atopic dermatitis patients for eczema herpeticum. J Invest Dermatol 127, 1261-1263, doi:10.1038/sj.jid.5700657 (2007).
-
(2007)
J Invest Dermatol
, vol.127
, pp. 1261-1263
-
-
Peng, W.M.1
-
8
-
-
69349102719
-
Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum
-
513 e501-507
-
Gao, P. S., et al. Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum. J Allergy Clin Immunol 124, 507-513, 513 e501-507, doi:10.1016/j.jaci.2009.07.034 (2009).
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 507-513
-
-
Gao, P.S.1
-
9
-
-
79953660611
-
Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in IFN-gamma response
-
e961-965
-
Leung, D. Y., et al. Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in IFN-gamma response. J Allergy Clin Immunol 127, 965-973 e961-965, doi:10.1016/j.jaci.2011.02.010 (2011).
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 965-973
-
-
Leung, D.Y.1
-
10
-
-
36749017671
-
Impaired immune response to vaccinia virus inoculated at the site of cutaneous allergic inflammation
-
Scott, J. E., et al. Impaired immune response to vaccinia virus inoculated at the site of cutaneous allergic inflammation. J Allergy Clin Immunol 120, 1382-1388, doi:10.1016/j.jaci.2007.08.004 (2007).
-
(2007)
J Allergy Clin Immunol
, vol.120
, pp. 1382-1388
-
-
Scott, J.E.1
-
11
-
-
84883416001
-
Atopic dermatitis complicated by eczema herpeticum is associated with HLA B7 and reduced interferongamma-producing CD8+ T cells
-
Mathias, R. A., et al. Atopic dermatitis complicated by eczema herpeticum is associated with HLA B7 and reduced interferongamma-producing CD8+ T cells. Br J Dermatol 169, 700-703, doi:10.1111/bjd.12382 (2013).
-
(2013)
Br J Dermatol
, vol.169
, pp. 700-703
-
-
Mathias, R.A.1
-
12
-
-
84945483552
-
Exaggerated IDO1 expression and activity in Langerhans cells from patients with atopic dermatitis upon viral stimulation: A potential predictive biomarker for high risk of Eczema herpeticum
-
Staudacher, A., Hinz, T., Novak, N., von Bubnoff, D., Bieber, T. Exaggerated IDO1 expression and activity in Langerhans cells from patients with atopic dermatitis upon viral stimulation: A potential predictive biomarker for high risk of Eczema herpeticum. Allergy. doi:10.1111/all.12699 (2015).
-
(2015)
Allergy
-
-
Staudacher, A.1
Hinz, T.2
Novak, N.3
Von Bubnoff, D.4
Bieber, T.5
-
13
-
-
84862495038
-
The differential production of cytokines by human Langerhans cells and dermal CD14(+) DCs controls CTL priming
-
Banchereau, J., et al. The differential production of cytokines by human Langerhans cells and dermal CD14(+) DCs controls CTL priming. Blood 119, 5742-5749, doi:10.1182/blood-2011-08-371245 (2012).
-
(2012)
Blood
, vol.119
, pp. 5742-5749
-
-
Banchereau, J.1
-
14
-
-
34047130119
-
Thymic stromal lymphopoietin converts human epidermal Langerhans cells into antigen-presenting cells that induce proallergic T cells
-
Ebner, S., et al. Thymic stromal lymphopoietin converts human epidermal Langerhans cells into antigen-presenting cells that induce proallergic T cells. J Allergy Clin Immunol 119, 982-990, doi:10.1016/j.jaci.2007.01.003 (2007).
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 982-990
-
-
Ebner, S.1
-
15
-
-
0036301998
-
Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP
-
Soumelis, V., et al. Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP. Nat Immunol 3, 673-680, doi:10.1038/ni805 (2002).
-
(2002)
Nat Immunol
, vol.3
, pp. 673-680
-
-
Soumelis, V.1
-
16
-
-
80052259758
-
Lesional dendritic cells in patients with chronic atopic dermatitis and psoriasis exhibit parallel ability to activate T-cell subsets
-
e571-512
-
Fujita, H., et al. Lesional dendritic cells in patients with chronic atopic dermatitis and psoriasis exhibit parallel ability to activate T-cell subsets. J Allergy Clin Immunol 128, 574-582 e571-512, doi:10.1016/j.jaci.2011.05.016 (2011).
-
(2011)
J Allergy Clin Immunol
, vol.128
, pp. 574-582
-
-
Fujita, H.1
-
17
-
-
84884297351
-
An expression atlas of human primary cells: Inference of gene function from coexpression networks
-
Mabbott, N. A., Baillie, J. K., Brown, H., Freeman, T. C., Hume, D. A. An expression atlas of human primary cells: Inference of gene function from coexpression networks. BMC Genomics 14, 632, doi:10.1186/1471-2164-14-632 (2013).
-
(2013)
BMC Genomics
, vol.14
, pp. 632
-
-
Mabbott, N.A.1
Baillie, J.K.2
Brown, H.3
Freeman, T.C.4
Hume, D.A.5
-
18
-
-
84894102230
-
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
-
Xue, J., et al. Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity 40, 274-288, doi:10.1016/j.immuni.2014.01.006 (2014).
-
(2014)
Immunity
, vol.40
, pp. 274-288
-
-
Xue, J.1
-
19
-
-
70349882120
-
Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses
-
(New York, N.Y.)
-
Amit, I., et al. Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses. Science (New York, N.Y.) 326, 257-263, doi:10.1126/science.1179050 (2009).
-
(2009)
Science
, vol.326
, pp. 257-263
-
-
Amit, I.1
-
20
-
-
84859313617
-
A framework for modeling the relationship between cellular steady-state and stimulusresponsiveness
-
Loriaux, P. M., Hoffmann, A. A framework for modeling the relationship between cellular steady-state and stimulusresponsiveness. Methods Cell Biol 110, 81-109, doi:10.1016/b978-0-12-388403-9.00004-7 (2012).
-
(2012)
Methods Cell Biol
, vol.110
, pp. 81-109
-
-
Loriaux, P.M.1
Hoffmann, A.2
-
21
-
-
84908507087
-
Identification of key regulators in glycogen utilization in E. Coli based on the simulations from a hybrid functional Petri net model
-
Tian, Z., Faure, A., Mori, H., Matsuno, H. Identification of key regulators in glycogen utilization in E. coli based on the simulations from a hybrid functional Petri net model. BMC Syst Biol 7 (Suppl 6), S1, doi:10.1186/1752-0509-7-s6-s1 (2013).
-
(2013)
BMC Syst Biol
, vol.7
, Issue.6
, pp. 51
-
-
Tian, Z.1
Faure, A.2
Mori, H.3
Matsuno, H.4
-
22
-
-
84869411578
-
Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-kappaB pathways
-
Shih, V. F., et al. Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-kappaB pathways. Nat Immunol 13, 1162-1170, doi:10.1038/ni.2446 (2012).
-
(2012)
Nat Immunol
, vol.13
, pp. 1162-1170
-
-
Shih, V.F.1
-
23
-
-
50849139175
-
Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system
-
Laslo, P., Pongubala, J. M., Lancki, D. W., Singh, H. Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system. Semin Immunol 20, 228-235, doi:10.1016/j.smim.2008.08.003 (2008).
-
(2008)
Semin Immunol
, vol.20
, pp. 228-235
-
-
Laslo, P.1
Pongubala, J.M.2
Lancki, D.W.3
Singh, H.4
-
24
-
-
40149110854
-
The signaling petri net-based simulator: A non-parametric strategy for characterizing the dynamics of cell-specific signaling networks
-
Ruths, D., Muller, M., Tseng, J. T., Nakhleh, L., Ram, P. T. The signaling petri net-based simulator: A non-parametric strategy for characterizing the dynamics of cell-specific signaling networks. PLoS Comput Biol 4, e1000005, doi:10.1371/journal.pcbi.1000005 (2008).
-
(2008)
PLoS Comput Biol
, vol.4
, pp. 1000005
-
-
Ruths, D.1
Muller, M.2
Tseng, J.T.3
Nakhleh, L.4
Ram, P.T.5
-
25
-
-
33847304166
-
Qualitatively modelling and analysing genetic regulatory networks: A Petri net approach
-
(Oxford, England)
-
Steggles, L. J., Banks, R., Shaw, O., Wipat, A. Qualitatively modelling and analysing genetic regulatory networks: A Petri net approach. Bioinformatics (Oxford, England) 23, 336-343, doi:10.1093/bioinformatics/btl596 (2007).
-
(2007)
Bioinformatics
, vol.23
, pp. 336-343
-
-
Steggles, L.J.1
Banks, R.2
Shaw, O.3
Wipat, A.4
-
26
-
-
84931415171
-
Batf2/Irf1 induces inflammatory responses in classically activated macrophages, lipopolysaccharides, mycobacterial infection
-
Roy, S., et al. Batf2/Irf1 Induces Inflammatory Responses in Classically Activated Macrophages, Lipopolysaccharides, Mycobacterial Infection. J Immunol 194, 6035-6044, doi:10.4049/jimmunol.1402521 (2015).
-
(2015)
J Immunol
, vol.194
, pp. 6035-6044
-
-
Roy, S.1
-
27
-
-
0035339391
-
PU.1 and multiple IFN regulatory factor proteins synergize to mediate transcriptional activation of the human IL-1 beta gene
-
Marecki, S., Riendeau, C. J., Liang, M. D., Fenton, M. J. PU.1 and multiple IFN regulatory factor proteins synergize to mediate transcriptional activation of the human IL-1 beta gene. J Immunol 166, 6829-6838 (2001).
-
(2001)
J Immunol
, vol.166
, pp. 6829-6838
-
-
Marecki, S.1
Riendeau, C.J.2
Liang, M.D.3
Fenton, M.J.4
-
28
-
-
11244336489
-
Synergistic activation of interleukin-12 p35 gene transcription by interferon regulatory factor-1 and interferon consensus sequence-binding protein
-
Liu, J., Guan, X., Tamura, T., Ozato, K., Ma, X. Synergistic activation of interleukin-12 p35 gene transcription by interferon regulatory factor-1 and interferon consensus sequence-binding protein. J Biol Chem 279, 55609-55617, doi:10.1074/jbc. M406565200 (2004).
-
(2004)
J Biol Chem
, vol.279
, pp. 55609-55617
-
-
Liu, J.1
Guan, X.2
Tamura, T.3
Ozato, K.4
Ma, X.5
-
29
-
-
84890918547
-
Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation
-
Williams, J. W., et al. Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation. Nature communications 4, 2990, doi:10.1038/ncomms3990 (2013).
-
(2013)
Nature Communications
, vol.4
, pp. 2990
-
-
Williams, J.W.1
-
30
-
-
68149125188
-
IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines
-
Ahyi, A. N., Chang, H. C., Dent, A. L., Nutt, S. L., Kaplan, M. H. IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines. J Immunol 183, 1598-1606, doi:10.4049/jimmunol.0803302 (2009).
-
(2009)
J Immunol
, vol.183
, pp. 1598-1606
-
-
Ahyi, A.N.1
Chang, H.C.2
Dent, A.L.3
Nutt, S.L.4
Kaplan, M.H.5
-
31
-
-
84929661740
-
Klf4 expression in conventional dendritic cells is required for T helper 2 cell responses
-
Tussiwand, R., et al. Klf4 expression in conventional dendritic cells is required for T helper 2 cell responses. Immunity 42, 916-928, doi:10.1016/j.immuni.2015.04.017 (2015).
-
(2015)
Immunity
, vol.42
, pp. 916-928
-
-
Tussiwand, R.1
-
32
-
-
84869116884
-
A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes
-
(New York, N.Y.)
-
Glasmacher, E., et al. A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes. Science (New York, N.Y.) 338, 975-980, doi:10.1126/science.1228309 (2012).
-
(2012)
Science
, vol.338
, pp. 975-980
-
-
Glasmacher, E.1
-
33
-
-
80052321986
-
Genome-wide analysis of interferon regulatory factor I binding in primary human monocytes
-
Shi, L., Perin, J. C., Leipzig, J., Zhang, Z., Sullivan, K. E. Genome-wide analysis of interferon regulatory factor I binding in primary human monocytes. Gene 487, 21-28, doi:10.1016/j.gene.2011.07.004 (2011).
-
(2011)
Gene
, vol.487
, pp. 21-28
-
-
Shi, L.1
Perin, J.C.2
Leipzig, J.3
Zhang, Z.4
Sullivan, K.E.5
-
34
-
-
33845439862
-
IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features
-
Gabriele, L., et al. IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features. J Leukoc Biol 80, 1500-1511, doi:10.1189/jlb.0406246 (2006).
-
(2006)
J Leukoc Biol
, vol.80
, pp. 1500-1511
-
-
Gabriele, L.1
-
35
-
-
0037032471
-
IRF-8/ICSBP and IRF-1 cooperatively stimulate mouse IL-12 promoter activity in macrophages
-
Masumi, A., Tamaoki, S., Wang, I. M., Ozato, K., Komuro, K. IRF-8/ICSBP and IRF-1 cooperatively stimulate mouse IL-12 promoter activity in macrophages. FEBS Lett 531, 348-353 (2002).
-
(2002)
FEBS Lett
, vol.531
, pp. 348-353
-
-
Masumi, A.1
Tamaoki, S.2
Wang, I.M.3
Ozato, K.4
Komuro, K.5
-
36
-
-
74049143556
-
An improved empirical bayes approach to estimating differential gene expression in microarray time-course data: BETR (Bayesian Estimation of Temporal Regulation)
-
Aryee, M. J., Gutierrez-Pabello, J. A., Kramnik, I., Maiti, T., Quackenbush, J. An improved empirical bayes approach to estimating differential gene expression in microarray time-course data: BETR (Bayesian Estimation of Temporal Regulation). BMC Bioinformatics 10, 409, doi:10.1186/1471-2105-10-409 (2009).
-
(2009)
BMC Bioinformatics
, vol.10
, pp. 409
-
-
Aryee, M.J.1
Gutierrez-Pabello, J.A.2
Kramnik, I.3
Maiti, T.4
Quackenbush, J.5
-
37
-
-
33646147811
-
MaSigPro: A method to identify significantly differential expression profiles in timecourse microarray experiments
-
(Oxford England)
-
Conesa, A., Nueda, M. J., Ferrer, A., Talon, M. maSigPro: A method to identify significantly differential expression profiles in timecourse microarray experiments. Bioinformatics (Oxford, England) 22, 1096-1102, doi:10.1093/bioinformatics/btl056 (2006).
-
(2006)
Bioinformatics
, vol.22
, pp. 1096-1102
-
-
Conesa, A.1
Nueda, M.J.2
Ferrer, A.3
Talon, M.4
-
38
-
-
35748937331
-
Construction, visualisation, clustering of transcription networks from microarray expression data
-
Freeman, T. C., et al. Construction, visualisation, clustering of transcription networks from microarray expression data. PLoS Comput Biol 3, 2032-2042, doi:10.1371/journal.pcbi.0030206 (2007).
-
(2007)
PLoS Comput Biol
, vol.3
, pp. 2032-2042
-
-
Freeman, T.C.1
-
39
-
-
85018734983
-
-
D-NLM: PMC101833 EDAT-2002/03/28, 10:00 MHDA-2002/05/04, 10:01 CRDT-2002/03/28, 10:00 PST-ppublish
-
Enright, A. J., Van Dongen S F-O, C. A., Ouzounis, C. A. An efficient algorithm for large-scale detection of protein families. doi: D-NLM: PMC101833 EDAT-2002/03/28 10:00 MHDA-2002/05/04 10:01 CRDT-2002/03/28 10:00 PST-ppublish (2002).
-
(2002)
An Efficient Algorithm for Large-scale Detection of Protein Families
-
-
Enright, A.J.1
Van Dongen, S.F.-O.C.A.2
Ouzounis, C.A.3
-
40
-
-
67849130563
-
ToppGene Suite for gene list enrichment analysis and candidate gene prioritization
-
Chen, J., Bardes, E. E., Aronow, B. J., Jegga, A. G. ToppGene Suite for gene list enrichment analysis and candidate gene prioritization. Nucleic Acids Res 37, W305-W311, doi:10.1093/nar/gkp427 (2009).
-
(2009)
Nucleic Acids Res
, vol.37
, pp. W305-W311
-
-
Chen, J.1
Bardes, E.E.2
Aronow, B.J.3
Jegga, A.G.4
-
41
-
-
84899941272
-
Gene regulatory networks in the immune system
-
Singh, H., Khan, A. A., Dinner, A. R. Gene regulatory networks in the immune system. Trends Immunol 35, 211-218, doi:10.1016/j. it.2014.03.006 (2014).
-
(2014)
Trends Immunol
, vol.35
, pp. 211-218
-
-
Singh, H.1
Khan, A.A.2
Dinner, A.R.3
-
42
-
-
84867884822
-
Compensatory dendritic cell development mediated by BATF-IRF interactions
-
Tussiwand, R., et al. Compensatory dendritic cell development mediated by BATF-IRF interactions. Nature 490, 502-507, doi:10.1038/nature11531 (2012).
-
(2012)
Nature
, vol.490
, pp. 502-507
-
-
Tussiwand, R.1
-
43
-
-
84857195761
-
A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation
-
Ochiai, K., et al. A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation. Nat Immunol 13, 300-307, doi:10.1038/ni.2210 (2012).
-
(2012)
Nat Immunol
, vol.13
, pp. 300-307
-
-
Ochiai, K.1
-
44
-
-
70349728484
-
A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates
-
Spooner, C. J., Cheng, J. X., Pujadas, E., Laslo, P., Singh, H. A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates. Immunity 31, 576-586, doi:10.1016/j.immuni.2009.07.011 (2009).
-
(2009)
Immunity
, vol.31
, pp. 576-586
-
-
Spooner, C.J.1
Cheng, J.X.2
Pujadas, E.3
Laslo, P.4
Singh, H.5
-
46
-
-
84988857241
-
Modelling the structure and dynamics of biological pathways
-
O'Hara, L., et al. Modelling the Structure and Dynamics of Biological Pathways. PLoS Biol 14, e1002530, doi:10.1371/journal. pbio.1002530 (2016).
-
(2016)
PLoS Biol
, vol.14
, pp. 1002530
-
-
O'Hara, L.1
-
47
-
-
84867861268
-
BATF-JUN is critical for IRF4-mediated transcription in T cells
-
Li, P., et al. BATF-JUN is critical for IRF4-mediated transcription in T cells. Nature 490, 543-546, doi:10.1038/nature11530 (2012).
-
(2012)
Nature
, vol.490
, pp. 543-546
-
-
Li, P.1
-
48
-
-
78349308548
-
Understanding the temporal codes of intra-cellular signals
-
Behar, M., Hoffmann, A. Understanding the temporal codes of intra-cellular signals. Curr Opin Genet Dev 20, 684-693, doi:10.1016/j.gde.2010.09.007 (2010).
-
(2010)
Curr Opin Genet Dev
, vol.20
, pp. 684-693
-
-
Behar, M.1
Hoffmann, A.2
-
49
-
-
84884738365
-
Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria
-
Berghout, J., et al. Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria. PLoS Pathog 9, e1003491, doi:10.1371/journal.ppat.1003491 (2013).
-
(2013)
PLoS Pathog
, vol.9
, pp. 1003491
-
-
Berghout, J.1
-
50
-
-
11144234196
-
Mature myeloid dendritic cell subsets have distinct roles for activation and viability of circulating human natural killer cells
-
Munz, C., et al. Mature myeloid dendritic cell subsets have distinct roles for activation and viability of circulating human natural killer cells. Blood 105, 266-273, doi:10.1182/blood-2004-06-2492 (2005).
-
(2005)
Blood
, vol.105
, pp. 266-273
-
-
Munz, C.1
-
51
-
-
4043055798
-
Mature human Langerhans cells derived from CD34+ hematopoietic progenitors stimulate greater cytolytic T lymphocyte activity in the absence of bioactive IL-12p70, by either single peptide presentation or cross-priming, than do dermalinterstitial or monocyte-derived dendritic cells
-
Ratzinger, G., et al. Mature human Langerhans cells derived from CD34+ hematopoietic progenitors stimulate greater cytolytic T lymphocyte activity in the absence of bioactive IL-12p70, by either single peptide presentation or cross-priming, than do dermalinterstitial or monocyte-derived dendritic cells. J Immunol 173, 2780-2791 (2004).
-
(2004)
J Immunol
, vol.173
, pp. 2780-2791
-
-
Ratzinger, G.1
-
52
-
-
24744435115
-
Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
-
Camps, M., et al. Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nat Med 11, 936-943, doi:10.1038/nm1284 (2005).
-
(2005)
Nat Med
, vol.11
, pp. 936-943
-
-
Camps, M.1
-
53
-
-
84878191150
-
IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses
-
Schlitzer, A., et al. IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses. Immunity 38, 970-983, doi:10.1016/j.immuni.2013.04.011 (2013).
-
(2013)
Immunity
, vol.38
, pp. 970-983
-
-
Schlitzer, A.1
-
54
-
-
84892815323
-
Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation
-
Vander Lugt, B., et al. Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation. Nat Immunol, doi:10.1038/ni.2795 (2013).
-
(2013)
Nat Immunol
-
-
Vander Lugt, B.1
-
55
-
-
84928568291
-
IRF8 directs stress-induced autophagy in macrophages and promotes clearance of Listeria monocytogenes
-
Gupta, M., et al. IRF8 directs stress-induced autophagy in macrophages and promotes clearance of Listeria monocytogenes. Nature communications 6, 6379, doi:10.1038/ncomms7379 (2015).
-
(2015)
Nature Communications
, vol.6
, pp. 6379
-
-
Gupta, M.1
-
56
-
-
84896527869
-
IRF4 in dendritic cells inhibits IL-12 production and controls Th1 immune responses against Leishmania major
-
Akbari, M., et al. IRF4 in dendritic cells inhibits IL-12 production and controls Th1 immune responses against Leishmania major. J Immunol 192, 2271-2279, doi:10.4049/jimmunol.1301914 (2014).
-
(2014)
J Immunol
, vol.192
, pp. 2271-2279
-
-
Akbari, M.1
-
57
-
-
85044518992
-
Psoriasis drug development and GWAS interpretation through in silico analysis of transcription factor binding sites
-
Swindell, W. R., et al. Psoriasis drug development and GWAS interpretation through in silico analysis of transcription factor binding sites. Clin Transl Med 4, 13, doi:10.1186/s40169-015-0054-5 (2015).
-
(2015)
Clin Transl Med
, vol.4
, pp. 13
-
-
Swindell, W.R.1
-
58
-
-
84923326765
-
Genetic and epigenetic fine mapping of causal autoimmune disease variants
-
Farh, K. K., et al. Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature 518, 337-343, doi:10.1038/nature13835 (2015).
-
(2015)
Nature
, vol.518
, pp. 337-343
-
-
Farh, K.K.1
-
59
-
-
84874771424
-
Characterizing the relationship between steady state and response using analytical expressions for the steady states of mass action models
-
Loriaux, P. M., Tesler, G., Hoffmann, A. Characterizing the relationship between steady state and response using analytical expressions for the steady states of mass action models. PLoS Comput Biol 9, e1002901, doi:10.1371/journal.pcbi.1002901 (2013).
-
(2013)
PLoS Comput Biol
, vol.9
, pp. 1002901
-
-
Loriaux, P.M.1
Tesler, G.2
Hoffmann, A.3
-
61
-
-
48749085156
-
Encoding NF-kappaB temporal control in response to TNF: Distinct roles for the negative regulators IkappaBalpha and A20
-
Werner, S. L., et al. Encoding NF-kappaB temporal control in response to TNF: Distinct roles for the negative regulators IkappaBalpha and A20. Genes Dev 22, 2093-2101, doi:10.1101/gad.1680708 (2008).
-
(2008)
Genes Dev
, vol.22
, pp. 2093-2101
-
-
Werner, S.L.1
-
62
-
-
66449092314
-
Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen-A nd cytokinereceptor signaling specificity
-
Shih, V. F., et al. Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen-A nd cytokinereceptor signaling specificity. Proc Natl Acad Sci USA 106, 9619-9624, doi:10.1073/pnas.0812367106 (2009).
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9619-9624
-
-
Shih, V.F.1
-
63
-
-
24944489952
-
Stimulus specificity of gene expression programs determined by temporal control of IKK activity
-
(New York, N.Y.)
-
Werner, S. L., Barken, D., Hoffmann, A. Stimulus specificity of gene expression programs determined by temporal control of IKK activity. Science (New York, N.Y.) 309, 1857-1861, doi:10.1126/science.1113319 (2005).
-
(2005)
Science
, vol.309
, pp. 1857-1861
-
-
Werner, S.L.1
Barken, D.2
Hoffmann, A.3
-
64
-
-
40149110264
-
Parameter estimate of signal transduction pathways
-
Arisi, I., Cattaneo, A., Rosato, V. Parameter estimate of signal transduction pathways. BMC neuroscience 7 (Suppl 1), S6, doi:10.1186/1471-2202-7-s1-s6 (2006).
-
(2006)
BMC Neuroscience
, vol.7
, Issue.1
, pp. 56
-
-
Arisi, I.1
Cattaneo, A.2
Rosato, V.3
-
65
-
-
0034995375
-
Complex biology with no parameters
-
Bailey, J. E. Complex biology with no parameters. Nature biotechnology 19, 503-504, doi:10.1038/89204 (2001).
-
(2001)
Nature Biotechnology
, vol.19
, pp. 503-504
-
-
Bailey, J.E.1
-
66
-
-
13444278821
-
Reconstruction of cellular signalling networks and analysis of their properties
-
Papin, J. A., Hunter, T., Palsson, B. O., Subramaniam, S. Reconstruction of cellular signalling networks and analysis of their properties. Nature reviews. Molecular cell biology 6, 99-111, doi:10.1038/nrm1570 (2005).
-
(2005)
Nature Reviews. Molecular Cell Biology
, vol.6
, pp. 99-111
-
-
Papin, J.A.1
Hunter, T.2
Palsson, B.O.3
Subramaniam, S.4
-
67
-
-
80053131464
-
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production
-
Li, S., Wang, L., Berman, M., Kong, Y. Y., Dorf, M. E. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. Immunity 35, 426-440, doi:10.1016/j.immuni.2011.06.014 (2011).
-
(2011)
Immunity
, vol.35
, pp. 426-440
-
-
Li, S.1
Wang, L.2
Berman, M.3
Kong, Y.Y.4
Dorf, M.E.5
-
68
-
-
0015609281
-
The logical analysis of continuous, non-linear biochemical control networks
-
Glass, L., Kauffman, S. A. The logical analysis of continuous, non-linear biochemical control networks. Journal of theoretical biology 39, 103-129 (1973).
-
(1973)
Journal of Theoretical Biology
, vol.39
, pp. 103-129
-
-
Glass, L.1
Kauffman, S.A.2
-
69
-
-
0036300225
-
Modelling biological processes using workflow and Petri Net models
-
(Oxford, England)
-
Peleg, M., Yeh, I., Altman, R. B. Modelling biological processes using workflow and Petri Net models. Bioinformatics (Oxford, England) 18, 825-837 (2002).
-
(2002)
Bioinformatics
, vol.18
, pp. 825-837
-
-
Peleg, M.1
Yeh, I.2
Altman, R.B.3
-
70
-
-
80053449181
-
Integrating quantitative knowledge into a qualitative gene regulatory network
-
Bourdon, J., Eveillard, D., Siegel, A. Integrating quantitative knowledge into a qualitative gene regulatory network. PLoS Comput Biol 7, e1002157, doi:10.1371/journal.pcbi.1002157 (2011).
-
(2011)
PLoS Comput Biol
, vol.7
, pp. 1002157
-
-
Bourdon, J.1
Eveillard, D.2
Siegel, A.3
-
71
-
-
84982801341
-
Intrinsic limits to gene regulation by global crosstalk
-
Friedlander, T., Prizak, R., Guet, C. C., Barton, N. H., Tkacik, G. Intrinsic limits to gene regulation by global crosstalk. Nature communications 7, 12307, doi:10.1038/ncomms12307 (2016).
-
(2016)
Nature Communications
, vol.7
, pp. 12307
-
-
Friedlander, T.1
Prizak, R.2
Guet, C.C.3
Barton, N.H.4
Tkacik, G.5
-
72
-
-
84930808259
-
Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast
-
Csardi, G., Franks, A., Choi, D. S., Airoldi, E. M., Drummond, D. A. Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast. PLoS genetics 11, e1005206, doi:10.1371/journal.pgen.1005206 (2015).
-
(2015)
PLoS Genetics
, vol.11
, pp. 1005206
-
-
Csardi, G.1
Franks, A.2
Choi, D.S.3
Airoldi, E.M.4
Drummond, D.A.5
-
73
-
-
0034635452
-
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation
-
(New York, N.Y.)
-
Hirsch, E., et al. Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. Science (New York, N.Y.) 287, 1049-1053 (2000).
-
(2000)
Science
, vol.287
, pp. 1049-1053
-
-
Hirsch, E.1
-
74
-
-
33847239467
-
PI3K delta and PI3K gamma: Partners in crime in inflammation in rheumatoid arthritis and beyond
-
Rommel, C., Camps, M., Ji, H. PI3K delta and PI3K gamma: Partners in crime in inflammation in rheumatoid arthritis and beyond? Nature reviews. Immunology 7, 191-201, doi:10.1038/nri2036 (2007).
-
(2007)
Nature Reviews Immunology
, vol.7
, pp. 191-201
-
-
Rommel, C.1
Camps, M.2
Ji, H.3
-
75
-
-
84870984149
-
The therapeutic potential for Pi3k inhibitors in autoimmune rheumatic diseases
-
Banham-Hall, E., Clatworthy, M. R., Okkenhaug, K. The Therapeutic Potential for PI3K Inhibitors in Autoimmune Rheumatic Diseases. The open rheumatology journal 6, 245-258, doi:10.2174/1874312901206010245 (2012).
-
(2012)
The Open Rheumatology Journal
, vol.6
, pp. 245-258
-
-
Banham-Hall, E.1
Clatworthy, M.R.2
Okkenhaug, K.3
-
76
-
-
84888219144
-
PI3K-delta and PI3K-gamma inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models
-
Winkler, D. G., et al. PI3K-delta and PI3K-gamma inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models. Chemistry & biology 20, 1364-1374, doi:10.1016/j.chembiol.2013.09.017 (2013).
-
(2013)
Chemistry & Biology
, vol.20
, pp. 1364-1374
-
-
Winkler, D.G.1
-
77
-
-
4644232654
-
Defective dendritic cell migration and activation of adaptive immunity in PI3Kgamma-deficient mice
-
Del Prete, A., et al. Defective dendritic cell migration and activation of adaptive immunity in PI3Kgamma-deficient mice. The EMBO journal 23, 3505-3515, doi:10.1038/sj.emboj.7600361 (2004).
-
(2004)
The EMBO Journal
, vol.23
, pp. 3505-3515
-
-
Del Prete, A.1
-
78
-
-
84856072398
-
Skin effector memory T cells do not recirculate and provide immune protection in alemtuzumab-treated CTCL patients
-
Clark, R. A., et al. Skin effector memory T cells do not recirculate and provide immune protection in alemtuzumab-treated CTCL patients. Sci Transl Med 4, 117ra117, doi:10.1126/scitranslmed.3003008 (2012).
-
(2012)
Sci Transl Med
, vol.4
, pp. 117
-
-
Clark, R.A.1
-
79
-
-
77950160019
-
In vitro fertilization and embryo culture strongly impact the placental transcriptome in the mouse model
-
Fauque, P., et al. In vitro fertilization and embryo culture strongly impact the placental transcriptome in the mouse model. PLoS One 5, e9218, doi:10.1371/journal.pone.0009218 (2010).
-
(2010)
PLoS One
, vol.5
, pp. 9218
-
-
Fauque, P.1
-
80
-
-
84925426005
-
Modulation of the cancer cell transcriptome by culture media formulations and cell density
-
Kim, S. W., Kim, S. J., Langley, R. R., Fidler, I. J. Modulation of the cancer cell transcriptome by culture media formulations and cell density. Int J Oncol 46, 2067-2075, doi:10.3892/ijo.2015.2930 (2015).
-
(2015)
Int J Oncol
, vol.46
, pp. 2067-2075
-
-
Kim, S.W.1
Kim, S.J.2
Langley, R.R.3
Fidler, I.J.4
-
81
-
-
27144541524
-
In vitro expansion of human mesenchymal stem cells: Choice of serum is a determinant of cell proliferation, differentiation, gene expression, transcriptome stability
-
Shahdadfar, A., Fronsdal, K., Haug, T., Reinholt, F. P., Brinchmann, J. E. In vitro expansion of human mesenchymal stem cells: Choice of serum is a determinant of cell proliferation, differentiation, gene expression, transcriptome stability. Stem Cells 23, 1357-1366, doi:10.1634/stemcells.2005-0094 (2005).
-
(2005)
Stem Cells
, vol.23
, pp. 1357-1366
-
-
Shahdadfar, A.1
Fronsdal, K.2
Haug, T.3
Reinholt, F.P.4
Brinchmann, J.E.5
-
82
-
-
84938199992
-
Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells
-
Contoli, M., et al. Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells. Allergy 70, 910-920, doi:10.1111/all.12627 (2015).
-
(2015)
Allergy
, vol.70
, pp. 910-920
-
-
Contoli, M.1
-
83
-
-
84904981439
-
Molluscum contagiosum in a pediatric American Indian population: Incidence and risk factors
-
McCollum, A. M., et al. Molluscum contagiosum in a pediatric American Indian population: Incidence and risk factors. PLoS One 9, e103419, doi:10.1371/journal.pone.0103419 (2014).
-
(2014)
PLoS One
, vol.9
, pp. 103419
-
-
McCollum, A.M.1
-
84
-
-
84901283377
-
Association between atopy and herpetic eye disease: Results from the pacific ocular inflammation study
-
Borkar, D. S., et al. Association between atopy and herpetic eye disease: Results from the pacific ocular inflammation study. JAMA Ophthalmol 132, 326-331, doi:10.1001/jamaophthalmol.2013.6277 (2014).
-
(2014)
JAMA Ophthalmol
, vol.132
, pp. 326-331
-
-
Borkar, D.S.1
-
85
-
-
84861462335
-
Human epidermal Langerhans cells maintain immune homeostasis in skin by activating skin resident regulatory T cells
-
C. M., B.-A., T. S., K
-
Seneschal, J., Clark, R. A., Gehad, A., C. M., B.-A., T. S., K. Human epidermal Langerhans cells maintain immune homeostasis in skin by activating skin resident regulatory T cells. Immunity 36, 873-884 (2012).
-
(2012)
Immunity
, vol.36
, pp. 873-884
-
-
Seneschal, J.1
Clark, R.A.2
Gehad, A.3
-
86
-
-
84928470243
-
Relay of herpes simplex virus between Langerhans cells and dermal dendritic cells in human skin
-
Kim, M., et al. Relay of herpes simplex virus between Langerhans cells and dermal dendritic cells in human skin. PLoS Pathog 11, e1004812, doi:10.1371/journal.ppat.1004812 (2015).
-
(2015)
PLoS Pathog
, vol.11
, pp. 1004812
-
-
Kim, M.1
-
87
-
-
77956216918
-
Herpes simplex virus infects skin gamma delta T cells before Langerhans cells and impedes migration of infected Langerhans cells by inducing apoptosis and blocking E-cadherin downregulation
-
Puttur, F. K., et al. Herpes simplex virus infects skin gamma delta T cells before Langerhans cells and impedes migration of infected Langerhans cells by inducing apoptosis and blocking E-cadherin downregulation. J Immunol 185, 477-487, doi:10.4049/jimmunol.0904106 (2010).
-
(2010)
J Immunol
, vol.185
, pp. 477-487
-
-
Puttur, F.K.1
-
88
-
-
84919430574
-
Entry mechanisms of herpes simplex virus 1 into murine epidermis: Involvement of nectin-1 and herpesvirus entry mediator as cellular receptors
-
Petermann, P., et al. Entry mechanisms of herpes simplex virus 1 into murine epidermis: Involvement of nectin-1 and herpesvirus entry mediator as cellular receptors. J Virol 89, 262-274, doi:10.1128/jvi.02917-14 (2015).
-
(2015)
J Virol
, vol.89
, pp. 262-274
-
-
Petermann, P.1
|