-
1
-
-
84859169880
-
Drug development: Raise standards for preclinical cancer research
-
Begley CG and Ellis LM: Drug development: raise standards for preclinical cancer research. Nature 483: 531-533, 2012.
-
(2012)
Nature
, vol.483
, pp. 531-533
-
-
Begley, C.G.1
Ellis, L.M.2
-
2
-
-
80055088241
-
Believe it or not: How much can we rely on published data on potential drug targets?
-
Prinz F, Schlange T and Asadullah K: Believe it or not: how much can we rely on published data on potential drug targets? Nat Rev Drug Discov 10: 712, 2011.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 712
-
-
Prinz, F.1
Schlange, T.2
Asadullah, K.3
-
3
-
-
33846563409
-
Why most published research findings are false
-
Ioannidis JP: Why most published research findings are false. PLoS Med 2: e124, 2005.
-
(2005)
PLoS Med
, vol.2
, pp. e124
-
-
Ioannidis, J.P.1
-
4
-
-
84891614258
-
Reproducibility: The risks of the replication drive
-
Bissell M: Reproducibility: the risks of the replication drive. Nature 503: 333-334, 2013.
-
(2013)
Nature
, vol.503
, pp. 333-334
-
-
Bissell, M.1
-
5
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, et al: Mutations of the BRAF gene in human cancer. Nature 417: 949-954, 2002.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
6
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, et al: Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 2: 561-566, 1996.
-
(1996)
Nat Med
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
-
7
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman JA, Zejnullahu K, Mitsudomi T, et al: MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316: 1039-1043, 2007.
-
(2007)
Science
, vol.316
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
-
8
-
-
77952542786
-
Lung cancer cell lines: Useless artifacts or invaluable tools for medical science?
-
Gazdar AF, Gao B and Minna JD: Lung cancer cell lines: useless artifacts or invaluable tools for medical science? Lung Cancer 68: 309-318, 2010.
-
(2010)
Lung Cancer
, vol.68
, pp. 309-318
-
-
Gazdar, A.F.1
Gao, B.2
Minna, J.D.3
-
9
-
-
77956570532
-
Lung cancer cell lines as tools for biomedical discovery and research
-
Gazdar AF, Girard L, Lockwood WW, Lam WL and Minna JD: Lung cancer cell lines as tools for biomedical discovery and research. J Natl Cancer Inst 102: 1310-1321, 2010.
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 1310-1321
-
-
Gazdar, A.F.1
Girard, L.2
Lockwood, W.W.3
Lam, W.L.4
Minna, J.D.5
-
10
-
-
79953300698
-
The seed and soil hypothesis revisited - The role of tumor-stroma interactions in metastasis to different organs
-
Langley RR and Fidler IJ: The seed and soil hypothesis revisited - the role of tumor-stroma interactions in metastasis to different organs. Int J Cancer 128: 2527-2535, 2011.
-
(2011)
Int J Cancer
, vol.128
, pp. 2527-2535
-
-
Langley, R.R.1
Fidler, I.J.2
-
11
-
-
79953313814
-
Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma
-
Cascone T, Herynk MH, Xu L, et al: Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma. J Clin Invest 121: 1313-1328, 2011.
-
(2011)
J Clin Invest
, vol.121
, pp. 1313-1328
-
-
Cascone, T.1
Herynk, M.H.2
Xu, L.3
-
12
-
-
79952371255
-
Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy
-
Kim SJ, Kim JS, Park ES, Lee JS, et al: Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy. Neoplasia 13: 286-298, 2011.
-
(2011)
Neoplasia
, vol.13
, pp. 286-298
-
-
Kim, S.J.1
Kim, J.S.2
Park, E.S.3
Lee, J.S.4
-
13
-
-
34447560961
-
Analysis of gene expression data using BRB-ArrayTools
-
Simon R, Lam A, Li MC, Ngan M, Menenzes S and Zhao Y: Analysis of gene expression data using BRB-ArrayTools. Cancer Inform 3: 11-17, 2007.
-
(2007)
Cancer Inform
, vol.3
, pp. 11-17
-
-
Simon, R.1
Lam, A.2
Li, M.C.3
Ngan, M.4
Menenzes, S.5
Zhao, Y.6
-
14
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
-
Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408, 2001.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
16
-
-
0033987746
-
Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia
-
Druker BJ and Lydon NB: Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia. J Clin Invest 105: 3-7, 2000.
-
(2000)
J Clin Invest
, vol.105
, pp. 3-7
-
-
Druker, B.J.1
Lydon, N.B.2
-
17
-
-
77952950455
-
Cell line misidentification: The beginning of the end
-
American Type Culture Collection Standards Development Organization Workgroup ASN- 0002: Cell line misidentification: the beginning of the end. Nat Rev Cancer 10: 441-448, 2010.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 441-448
-
-
-
18
-
-
78649323066
-
Recommendation of short tandem repeat profiling for authenticating human cell lines, stem cells, and tissues
-
Barallon R, Bauer SR, Butler J, et al: Recommendation of short tandem repeat profiling for authenticating human cell lines, stem cells, and tissues. In Vitro Cell Dev Biol Anim 46: 727-732, 2010.
-
(2010)
In Vitro Cell Dev Biol Anim
, vol.46
, pp. 727-732
-
-
Barallon, R.1
Bauer, S.R.2
Butler, J.3
-
19
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY and Nieto MA: Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890, 2009.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
20
-
-
84887456252
-
The epigenetics of epithelial-mesenchymal plasticity in cancer
-
Tam WL and Weinberg RA: The epigenetics of epithelial-mesenchymal plasticity in cancer. Nat Med 19: 1438-1449, 2013.
-
(2013)
Nat Med
, vol.19
, pp. 1438-1449
-
-
Tam, W.L.1
Weinberg, R.A.2
-
21
-
-
84866324123
-
Cancer stem cells and epithelial-mesenchymal transition: Concepts and molecular links
-
Scheel C and Weinberg RA: Cancer stem cells and epithelial-mesenchymal transition: concepts and molecular links. Semin Cancer Biol 22: 396-403, 2012.
-
(2012)
Semin Cancer Biol
, vol.22
, pp. 396-403
-
-
Scheel, C.1
Weinberg, R.A.2
-
22
-
-
84898547220
-
Endothelin-1 mediated high glucose-induced epithelial-mesenchymal transition in renal tubular cells
-
Tang L, Li H, Gou R, Cheng G, Guo Y, Fang Y and Chen F: Endothelin-1 mediated high glucose-induced epithelial-mesenchymal transition in renal tubular cells. Diabetes Res Clin Pract 104: 176-182, 2014.
-
(2014)
Diabetes Res Clin Pract
, vol.104
, pp. 176-182
-
-
Tang, L.1
Li, H.2
Gou, R.3
Cheng, G.4
Guo, Y.5
Fang, Y.6
Chen, F.7
-
23
-
-
62149135860
-
HGF and BMP-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesothelium
-
Yu MA, Shin KS, Kim JH, et al: HGF and BMP-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesothelium. J Am Soc Nephrol 20: 567-581, 2009.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 567-581
-
-
Yu, M.A.1
Shin, K.S.2
Kim, J.H.3
-
24
-
-
84890118522
-
Metabolic regulation of cancer cell side population by glucose through activation of the Akt pathway
-
Liu PP, Liao J, Tang ZJ, et al: Metabolic regulation of cancer cell side population by glucose through activation of the Akt pathway. Cell Death Differ 21: 124-135, 2014.
-
(2014)
Cell Death Differ
, vol.21
, pp. 124-135
-
-
Liu, P.P.1
Liao, J.2
Tang, Z.J.3
-
25
-
-
72449200272
-
Integrin (alpha6beta4) signals through Src to increase expression of S100A4, a metastasis-promoting factor: Implications for cancer cell invasion
-
Kim TH, Kim HI, Soung YH, Shaw LA and Chung J: Integrin (alpha6beta4) signals through Src to increase expression of S100A4, a metastasis-promoting factor: implications for cancer cell invasion. Mol Cancer Res 7: 1605-1612, 2009.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1605-1612
-
-
Kim, T.H.1
Kim, H.I.2
Soung, Y.H.3
Shaw, L.A.4
Chung, J.5
-
27
-
-
58149232586
-
The interleukin-8 pathway in cancer
-
Waugh DJ and Wilson C: The interleukin-8 pathway in cancer. Clin Cancer Res 14: 6735-6741, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6735-6741
-
-
Waugh, D.J.1
Wilson, C.2
-
28
-
-
84884204462
-
Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells
-
Singh JK, Simões BM, Howell SJ, Farnie G and Clarke RB: Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells. Breast Cancer Res 15: 210, 2013.
-
(2013)
Breast Cancer Res
, vol.15
, pp. 210
-
-
Singh, J.K.1
Simões, B.M.2
Howell, S.J.3
Farnie, G.4
Clarke, R.B.5
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