Targeting colorectal cancer proliferation, stemness and metastatic potential using Brassicaceae extracts enriched in isothiocyanates: A 3D cell model-based study

Nutrients

Volumn 9, Issue 4, 2017, Pages

  Pereira, Lucília P ^a,b   Silva, Patrícia ^c   Duarte, Marlene ^c   Rodrigues, Liliana ^a,b   Duarte, Catarina M M ^a,b   Albuquerque, Cristina ^c   Serra, Ana Teresa ^a,b  

^a INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLÓGICA   (Portugal)

^b INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^c INSTITUTO PORTUGUÊS DE ONCOLOGIA DE LISBOA FRANCISCO GENTIL   (Portugal)

Author keywords

Brassicaceae extracts; Broccoli; Cancer stem cells; Colorectal cancer; Metastasis; Phenethyl isothiocyanate; Sulforaphane; Watercress

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 1; BETA CATENIN; BROCCOLI EXTRACT; CD133 ANTIGEN; CYCLIN A; GELATINASE A; GELATINASE B; ISOTHIOCYANIC ACID; LEUCINE RICH REPEAT CONTAINING G PROTEIN; PEPTIDES AND PROTEINS; PHENETHYL ISOTHIOCYANATE; PLANT EXTRACT; PROMININ 1; SULFORAPHANE; UNCLASSIFIED DRUG; WATERCRESS EXTRACT; WNT PROTEIN; ANTINEOPLASTIC AGENT; CARBON DIOXIDE; ISOTHIOCYANIC ACID DERIVATIVE; SOLVENT; SULFORAFAN; TUMOR MARKER;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BRASSICACEAE; CELL CYCLE ARREST; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; COLORECTAL CANCER; CONTROLLED STUDY; CYTOTOXICITY ASSAY; DNA DAMAGE; DOWN REGULATION; DRUG MECHANISM; EC50; ENZYME ACTIVITY; FLOW CYTOMETRY; FLUOROMETRY; G2 PHASE CELL CYCLE CHECKPOINT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; MASS FRAGMENTOGRAPHY; METASTASIS; PHYTOCHEMISTRY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR GROWTH; UPREGULATION; WNT SIGNALING PATHWAY; ANALYSIS; BRASSICA; CACO-2 CELL LINE; CELL DIFFERENTIATION; CHEMISTRY; COLORECTAL NEOPLASMS; DIET THERAPY; DIETARY SUPPLEMENT; DRUG RESISTANCE; ECONOMICS; GENE EXPRESSION REGULATION; GENETICS; HT-29 CELL LINE; ISOLATION AND PURIFICATION; METABOLISM; MULTICELLULAR SPHEROID; NASTURTIUM; NEOPLASM METASTASIS; PATHOLOGY;

ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOMARKERS, TUMOR; BRASSICA; CACO-2 CELLS; CARBON DIOXIDE; CELL DIFFERENTIATION; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DIETARY SUPPLEMENTS; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HT29 CELLS; HUMANS; ISOTHIOCYANATES; NASTURTIUM; NEOPLASM METASTASIS; PLANT EXTRACTS; SOLVENTS; SPHEROIDS, CELLULAR;

EID: 85018480043     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu9040368     Document Type: Article

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