LGR5 is required for the maintenance of spheroid-derived colon cancer stem cells

International Journal of Molecular Medicine

Volumn 34, Issue 1, 2014, Pages 35-42

  Chen, Xiang ^a   Wei, Bo ^a   Han, Xiaoyan ^a   Zheng, Zongheng ^a   Huang, Jianglong ^a   Liu, Jianpei ^a   Huang, Yong ^a   Wei, Hongbo ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Colon cancer stem cells; LGR5; Maintenance; Spheroid cells

Indexed keywords

CD133 ANTIGEN; CELL MARKER; HERMES ANTIGEN; LGR5 PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CD44 PROTEIN, HUMAN; CISPLATIN; FLUOROURACIL; G PROTEIN COUPLED RECEPTOR; GLYCOPROTEIN; LEUKOCYTE ANTIGEN; LGR5 PROTEIN, HUMAN; PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER RECURRENCE; CANCER STEM CELL; CARCINOGENICITY; CELL ASSAY; CELL CYCLE G0 PHASE; CELL INVASION; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; DOWN REGULATION; G1 PHASE CELL CYCLE CHECKPOINT; GENE SILENCING; HT 29 CELL LINE; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SPHEROID CELL; TUMOR GROWTH; ANTAGONISTS AND INHIBITORS; CELL MOTION; DRUG EFFECTS; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; SIGNAL TRANSDUCTION;

ANTIGENS, CD; ANTIGENS, CD44; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL MOVEMENT; CELL PROLIFERATION; CISPLATIN; DRUG RESISTANCE, NEOPLASM; FLUOROURACIL; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; HT29 CELLS; HUMANS; NEOPLASTIC STEM CELLS; PEPTIDES; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, G-PROTEIN-COUPLED; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR;

EID: 84902660162     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1752     Document Type: Article

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