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Volumn 35, Issue , 2017, Pages 31-52

The lymphatic system: Integral roles in immunity

Author keywords

Adhesion; Endothelium; Lymph; Lymph node; Migration

Indexed keywords

PROTEIN;

EID: 85018361678     PISSN: 07320582     EISSN: 15453278     Source Type: Book Series    
DOI: 10.1146/annurev-immunol-041015-055354     Document Type: Review
Times cited : (244)

References (148)
  • 1
    • 84862777442 scopus 로고    scopus 로고
    • Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity
    • Jiang X, Clark RA, Liu L, Wagers AJ, Fuhlbrigge RC, Kupper TS. 2012. Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity. Nature 483:227-31
    • (2012) Nature , vol.483 , pp. 227-231
    • Jiang, X.1    Clark, R.A.2    Liu, L.3    Wagers, A.J.4    Fuhlbrigge, R.C.5    Kupper, T.S.6
  • 2
    • 84928904487 scopus 로고    scopus 로고
    • Quantifying Memory CD8 T cells reveals regionalization of immunosurveillance
    • Steinert EM, Schenkel JM, Fraser KA, Beura LK, Manlove LS, et al. 2015. Quantifying Memory CD8 T cells reveals regionalization of immunosurveillance. Cell 161:737-49
    • (2015) Cell , vol.161 , pp. 737-749
    • Steinert, E.M.1    Schenkel, J.M.2    Fraser, K.A.3    Beura, L.K.4    Manlove, L.S.5
  • 3
    • 0035937587 scopus 로고    scopus 로고
    • Preferential localization of effectormemory cells in nonlymphoid tissue
    • Masopust D, Vezys V, Marzo AL, Lefrancois L. 2001. Preferential localization of effectormemory cells in nonlymphoid tissue. Science 291:2413-17
    • (2001) Science , vol.291 , pp. 2413-2417
    • Masopust, D.1    Vezys, V.2    Marzo, A.L.3    Lefrancois, L.4
  • 4
    • 0035282433 scopus 로고    scopus 로고
    • Visualizing the generation of memory CD4 T cells in the whole body
    • Reinhardt RL, Khoruts A, Merica R, Zell T, Jenkins MK. 2001. Visualizing the generation of memory CD4 T cells in the whole body. Nature 410:101-5
    • (2001) Nature , vol.410 , pp. 101-105
    • Reinhardt, R.L.1    Khoruts, A.2    Merica, R.3    Zell, T.4    Jenkins, M.K.5
  • 6
    • 84867900263 scopus 로고    scopus 로고
    • HEVs, lymphatics and homeostatic immune cell trafficking in lymph nodes
    • Girard JP, Moussion C, Forster R. 2012. HEVs, lymphatics and homeostatic immune cell trafficking in lymph nodes. Nat. Rev. Immunol. 12:762-73
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 762-773
    • Girard, J.P.1    Moussion, C.2    Forster, R.3
  • 7
    • 84887524207 scopus 로고    scopus 로고
    • The spleen in local and systemic regulation of immunity
    • Bronte V, Pittet MJ. 2013. The spleen in local and systemic regulation of immunity. Immunity 39:806-18
    • (2013) Immunity , vol.39 , pp. 806-818
    • Bronte, V.1    Pittet, M.J.2
  • 8
    • 84896751585 scopus 로고    scopus 로고
    • Lymphatic transport of high-density lipoproteins and chylomicrons
    • Randolph GJ, Miller NE. 2014. Lymphatic transport of high-density lipoproteins and chylomicrons. J. Clin. Investig. 124:929-35
    • (2014) J. Clin. Investig. , vol.124 , pp. 929-935
    • Randolph, G.J.1    Miller, N.E.2
  • 9
    • 84900859470 scopus 로고    scopus 로고
    • Specific calcineurin targeting inmacrophages confers resistance to inflammation viaMKP-1 and p38
    • Escolano A, Martinez-Martinez S, Alfranca A, Urso K, Izquierdo HM, et al. 2014. Specific calcineurin targeting inmacrophages confers resistance to inflammation viaMKP-1 and p38. EMBO J. 33:1117-33
    • (2014) EMBO J. , vol.33 , pp. 1117-1133
    • Escolano, A.1    Martinez-Martinez, S.2    Alfranca, A.3    Urso, K.4    Izquierdo, H.M.5
  • 10
    • 0023162354 scopus 로고
    • Steady-state fluid filtration at different capillary pressures in perfused frog mesenteric capillaries
    • Michel CC, Phillips ME. 1987. Steady-state fluid filtration at different capillary pressures in perfused frog mesenteric capillaries. J. Physiol. 388:421-35
    • (1987) J. Physiol. , vol.388 , pp. 421-435
    • Michel, C.C.1    Phillips, M.E.2
  • 11
    • 77954321271 scopus 로고    scopus 로고
    • Microvascular fluid exchange and the revised Starling principle
    • Levick JR, Michel CC. 2010. Microvascular fluid exchange and the revised Starling principle. Cardiovasc. Res. 87:198-210
    • (2010) Cardiovasc. Res. , vol.87 , pp. 198-210
    • Levick, J.R.1    Michel, C.C.2
  • 12
    • 84920541310 scopus 로고    scopus 로고
    • LDL and HDL transfer rates across peripheral microvascular endothelium agree with those predicted for passive ultrafiltration in humans
    • Michel CC, Nanjee MN, Olszewski WL, Miller NE. 2015. LDL and HDL transfer rates across peripheral microvascular endothelium agree with those predicted for passive ultrafiltration in humans. J. Lipid Res. 56:122-28
    • (2015) J. Lipid Res. , vol.56 , pp. 122-128
    • Michel, C.C.1    Nanjee, M.N.2    Olszewski, W.L.3    Miller, N.E.4
  • 13
    • 84870798143 scopus 로고    scopus 로고
    • The diaphragms of fenestrated endothelia: Gatekeepers of vascular permeability and blood composition
    • Stan RV, Tse D, Deharvengt SJ, Smits NC, Xu Y, et al. 2012. The diaphragms of fenestrated endothelia: gatekeepers of vascular permeability and blood composition. Dev. Cell 23:1203-18
    • (2012) Dev. Cell , vol.23 , pp. 1203-1218
    • Stan, R.V.1    Tse, D.2    Deharvengt, S.J.3    Smits, N.C.4    Xu, Y.5
  • 14
    • 33644839612 scopus 로고    scopus 로고
    • Signaling mechanisms regulating endothelial permeability
    • Mehta D, Malik AB. 2006. Signaling mechanisms regulating endothelial permeability. Physiol. Rev. 86:279-367
    • (2006) Physiol. Rev. , vol.86 , pp. 279-367
    • Mehta, D.1    Malik, A.B.2
  • 15
    • 84969756508 scopus 로고    scopus 로고
    • Access of protective antiviral antibody to neuronal tissues requires CD4 T-cell help
    • Iijima N, Iwasaki A. 2016. Access of protective antiviral antibody to neuronal tissues requires CD4 T-cell help. Nature 533:552-56
    • (2016) Nature , vol.533 , pp. 552-556
    • Iijima, N.1    Iwasaki, A.2
  • 16
    • 84864075113 scopus 로고    scopus 로고
    • Interstitial fluid and lymph formation and transport: Physiological regulation and roles in inflammation and cancer
    • Wiig H, Swartz MA. 2012. Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer. Physiol. Rev. 92:1005-60
    • (2012) Physiol. Rev. , vol.92 , pp. 1005-1060
    • Wiig, H.1    Swartz, M.A.2
  • 17
    • 80053228071 scopus 로고    scopus 로고
    • Secretion of adipokines by human adipose tissue in vivo: Partitioning between capillary and lymphatic transport
    • Miller NE, Michel CC, Nanjee MN, Olszewski WL, Miller IP, et al. 2011. Secretion of adipokines by human adipose tissue in vivo: partitioning between capillary and lymphatic transport. Am. J. Physiol. Endocrinol. Metab. 301:E659-67
    • (2011) Am. J. Physiol. Endocrinol. Metab. , vol.301 , pp. E659-E667
    • Miller, N.E.1    Michel, C.C.2    Nanjee, M.N.3    Olszewski, W.L.4    Miller, I.P.5
  • 18
    • 79958798537 scopus 로고    scopus 로고
    • Lymphatic anatomy and biomechanics
    • Negrini D, Moriondo A. 2011. Lymphatic anatomy and biomechanics. J. Physiol. 589:2927-34
    • (2011) J. Physiol. , vol.589 , pp. 2927-2934
    • Negrini, D.1    Moriondo, A.2
  • 19
    • 0024373052 scopus 로고
    • Direct measurement of interstitial convection and diffusion of albumin in normal and neoplastic tissues by fluorescence photobleaching
    • Chary SR, Jain RK. 1989. Direct measurement of interstitial convection and diffusion of albumin in normal and neoplastic tissues by fluorescence photobleaching. PNAS 86:5385-89
    • (1989) PNAS , vol.86 , pp. 5385-5389
    • Chary, S.R.1    Jain, R.K.2
  • 20
    • 0037453703 scopus 로고    scopus 로고
    • Interstitial flow as a guide for lymphangiogenesis
    • Boardman KC, Swartz MA. 2003. Interstitial flow as a guide for lymphangiogenesis. Circ. Res. 92:801-8
    • (2003) Circ. Res. , vol.92 , pp. 801-808
    • Boardman, K.C.1    Swartz, M.A.2
  • 21
    • 23444451916 scopus 로고    scopus 로고
    • Dendritic-cell trafficking to lymph nodes through lymphatic vessels
    • Randolph GJ, Angeli V, Swartz MA. 2005. Dendritic-cell trafficking to lymph nodes through lymphatic vessels. Nat. Rev. Immunol. 5:617-28
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 617-628
    • Randolph, G.J.1    Angeli, V.2    Swartz, M.A.3
  • 22
    • 34249774277 scopus 로고    scopus 로고
    • Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling
    • Shields JD, Fleury ME, Yong C, Tomei AA, Randolph GJ, Swartz MA. 2007. Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling. Cancer Cell 11:526-38
    • (2007) Cancer Cell , vol.11 , pp. 526-538
    • Shields, J.D.1    Fleury, M.E.2    Yong, C.3    Tomei, A.A.4    Randolph, G.J.5    Swartz, M.A.6
  • 23
    • 84920602237 scopus 로고    scopus 로고
    • Modest hyperglycemia prevents interstitial dispersion of insulin in skeletal muscle
    • Kolka CM, Castro AV, Kirkman EL, Bergman RN. 2015. Modest hyperglycemia prevents interstitial dispersion of insulin in skeletal muscle. Metabolism 64:330-37
    • (2015) Metabolism , vol.64 , pp. 330-337
    • Kolka, C.M.1    Castro, A.V.2    Kirkman, E.L.3    Bergman, R.N.4
  • 24
    • 84940933110 scopus 로고    scopus 로고
    • Time lag of glucose from intravascular to interstitial compartment in type 1 diabetes
    • Basu A, Dube S, Veettil S, Slama M, Kudva YC, et al. 2015. Time lag of glucose from intravascular to interstitial compartment in type 1 diabetes. J. Diabetes Sci. Technol. 9:63-68
    • (2015) J. Diabetes Sci. Technol. , vol.9 , pp. 63-68
    • Basu, A.1    Dube, S.2    Veettil, S.3    Slama, M.4    Kudva, Y.C.5
  • 25
    • 78650269743 scopus 로고    scopus 로고
    • Estimating plasma glucose from interstitial glucose: The issue of calibration algorithms in commercial continuous glucosemonitoring devices
    • Rossetti P, Bondia J, Vehi J, Fanelli CG. 2010. Estimating plasma glucose from interstitial glucose: the issue of calibration algorithms in commercial continuous glucosemonitoring devices. Sensors 10:10936-52
    • (2010) Sensors , vol.10 , pp. 10936-10952
    • Rossetti, P.1    Bondia, J.2    Vehi, J.3    Fanelli, C.G.4
  • 26
    • 84941344937 scopus 로고    scopus 로고
    • Metabolic competition in the tumor microenvironment is a driver of cancer progression
    • Chang CH, Qiu J, O'Sullivan D, Buck MD, Noguchi T, et al. 2015. Metabolic competition in the tumor microenvironment is a driver of cancer progression. Cell 162:1229-41
    • (2015) Cell , vol.162 , pp. 1229-1241
    • Chang, C.H.1    Qiu, J.2    O'Sullivan, D.3    Buck, M.D.4    Noguchi, T.5
  • 27
    • 84857556564 scopus 로고    scopus 로고
    • Lymphatic and interstitial flow in the tumour microenvironment: Linking mechanobiology with immunity
    • Swartz MA, Lund AW. 2012. Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity. Nat. Rev. Cancer 12:210-19
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 210-219
    • Swartz, M.A.1    Lund, A.W.2
  • 28
    • 3342917164 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase regulates microlymphatic flow via collecting lymphatics
    • Hagendoorn J, Padera TP, Kashiwagi S, Isaka N, Noda F, et al. 2004. Endothelial nitric oxide synthase regulates microlymphatic flow via collecting lymphatics. Circ. Res. 95:204-9
    • (2004) Circ. Res. , vol.95 , pp. 204-209
    • Hagendoorn, J.1    Padera, T.P.2    Kashiwagi, S.3    Isaka, N.4    Noda, F.5
  • 29
    • 84877264563 scopus 로고    scopus 로고
    • Lymphatic vessels are essential for the removal of cholesterol from peripheral tissues by SR-BI-mediated transport of HDL
    • Lim HY, Thiam CH, Yeo KP, Bisoendial R, Hii CS, et al. 2013. Lymphatic vessels are essential for the removal of cholesterol from peripheral tissues by SR-BI-mediated transport of HDL. Cell Metab. 17:671-84
    • (2013) Cell Metab. , vol.17 , pp. 671-684
    • Lim, H.Y.1    Thiam, C.H.2    Yeo, K.P.3    Bisoendial, R.4    Hii, C.S.5
  • 30
    • 34948814992 scopus 로고    scopus 로고
    • Functionally specialized junctions between endothelial cells of lymphatic vessels
    • Baluk P, Fuxe J, Hashizume H, Romano T, Lashnits E, et al. 2007. Functionally specialized junctions between endothelial cells of lymphatic vessels. J. Exp. Med. 204:2349-62
    • (2007) J. Exp. Med. , vol.204 , pp. 2349-2362
    • Baluk, P.1    Fuxe, J.2    Hashizume, H.3    Romano, T.4    Lashnits, E.5
  • 31
    • 84861645540 scopus 로고    scopus 로고
    • Plasticity of button-like junctions in the endothelium of airway lymphatics in development and inflammation
    • Yao LC, Baluk P, Srinivasan RS, Oliver G, McDonald DM. 2012. Plasticity of button-like junctions in the endothelium of airway lymphatics in development and inflammation. Am. J. Pathol. 180:2561-75
    • (2012) Am. J. Pathol. , vol.180 , pp. 2561-2575
    • Yao, L.C.1    Baluk, P.2    Srinivasan, R.S.3    Oliver, G.4    McDonald, D.M.5
  • 34
    • 70349314647 scopus 로고    scopus 로고
    • Mechanical modes of 'amoeboid' cell migration
    • Lammermann T, Sixt M. 2009. Mechanical modes of 'amoeboid' cell migration. Curr. Opin. Cell Biol. 21:636-44
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 636-644
    • Lammermann, T.1    Sixt, M.2
  • 35
    • 73949156419 scopus 로고    scopus 로고
    • Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels
    • Pflicke H, Sixt M. 2009. Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels. J. Exp. Med. 206:2925-35
    • (2009) J. Exp. Med. , vol.206 , pp. 2925-2935
    • Pflicke, H.1    Sixt, M.2
  • 36
    • 84883153623 scopus 로고    scopus 로고
    • Inflammation-induced interstitial migration of effector CD4+ T cells is dependent on integrin aV
    • Overstreet MG, Gaylo A, Angermann BR, Hughson A, Hyun YM, et al. 2013. Inflammation-induced interstitial migration of effector CD4+ T cells is dependent on integrin aV. Nat. Immunol. 14:949-58
    • (2013) Nat. Immunol. , vol.14 , pp. 949-958
    • Overstreet, M.G.1    Gaylo, A.2    Angermann, B.R.3    Hughson, A.4    Hyun, Y.M.5
  • 37
    • 0027984587 scopus 로고
    • In vivo treatment with anti-ICAM-1 and anti-LFA-1 antibodies inhibits contact sensitization-induced migration of epidermal Langerhans cells to regional lymph nodes
    • Ma J, Wang JH, Guo YJ, Sy MS, Bigby M. 1994. In vivo treatment with anti-ICAM-1 and anti-LFA-1 antibodies inhibits contact sensitization-induced migration of epidermal Langerhans cells to regional lymph nodes. Cell Immunol. 158:389-99
    • (1994) Cell Immunol. , vol.158 , pp. 389-399
    • Ma, J.1    Wang, J.H.2    Guo, Y.J.3    Sy, M.S.4    Bigby, M.5
  • 38
    • 0034776392 scopus 로고    scopus 로고
    • The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node
    • Xu H, Guan H, Zu G, Bullard D, Hanson J, et al. 2001. The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node. Eur. J. Immunol. 31:3085-93
    • (2001) Eur. J. Immunol. , vol.31 , pp. 3085-3093
    • Xu, H.1    Guan, H.2    Zu, G.3    Bullard, D.4    Hanson, J.5
  • 39
    • 33751528001 scopus 로고    scopus 로고
    • An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium
    • Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG. 2006. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium. J. Exp. Med. 203:2763-77
    • (2006) J. Exp. Med. , vol.203 , pp. 2763-2777
    • Johnson, L.A.1    Clasper, S.2    Holt, A.P.3    Lalor, P.F.4    Baban, D.5    Jackson, D.G.6
  • 40
    • 0032702638 scopus 로고    scopus 로고
    • The reduced expression of 6Ckine in the plt mouse results from the deletion of one of two 6Ckine genes
    • Vassileva G, Soto H, Zlotnik A, Nakano H, Kakiuchi T, et al. 1999. The reduced expression of 6Ckine in the plt mouse results from the deletion of one of two 6Ckine genes. J. Exp. Med. 190:1183-88
    • (1999) J. Exp. Med. , vol.190 , pp. 1183-1188
    • Vassileva, G.1    Soto, H.2    Zlotnik, A.3    Nakano, H.4    Kakiuchi, T.5
  • 41
    • 0033214348 scopus 로고    scopus 로고
    • CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
    • Forster R, Schubel A, Breitfeld D, Kremmer E, Renner-Muller I, et al. 1999. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99:23-33
    • (1999) Cell , vol.99 , pp. 23-33
    • Forster, R.1    Schubel, A.2    Breitfeld, D.3    Kremmer, E.4    Renner-Muller, I.5
  • 42
    • 4143096772 scopus 로고    scopus 로고
    • CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions
    • Ohl L, Mohaupt M, Czeloth N, Hintzen G, Kiafard Z, et al. 2004. CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions. Immunity 21:279-88
    • (2004) Immunity , vol.21 , pp. 279-288
    • Ohl, L.1    Mohaupt, M.2    Czeloth, N.3    Hintzen, G.4    Kiafard, Z.5
  • 43
    • 84995887416 scopus 로고    scopus 로고
    • Lymphoid aggregates remodel lymphatic collecting vessels that serve mesenteric lymph nodes in Crohn disease
    • Randolph GJ, Bala S, Rahier JF, Johnson MW, Wang PL, et al. 2016. Lymphoid aggregates remodel lymphatic collecting vessels that serve mesenteric lymph nodes in Crohn disease. Am. J. Pathol. 186(12):3066-73
    • (2016) Am. J. Pathol. , vol.186 , Issue.12 , pp. 3066-3073
    • Randolph, G.J.1    Bala, S.2    Rahier, J.F.3    Johnson, M.W.4    Wang, P.L.5
  • 44
    • 24944569742 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues
    • Debes GF, Arnold CN, Young AJ, Krautwald S, Lipp M, et al. 2005. Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues. Nat. Immunol. 6:889-94
    • (2005) Nat. Immunol. , vol.6 , pp. 889-894
    • Debes, G.F.1    Arnold, C.N.2    Young, A.J.3    Krautwald, S.4    Lipp, M.5
  • 45
    • 84884226126 scopus 로고    scopus 로고
    • CCR7 plays no appreciable role in trafficking of central memory CD4 T cells to lymph nodes
    • Vander Lugt B, Tubo NJ, Nizza ST, Boes M, Malissen B, et al. 2013. CCR7 plays no appreciable role in trafficking of central memory CD4 T cells to lymph nodes. J. Immunol. 191:3119-27
    • (2013) J. Immunol. , vol.191 , pp. 3119-3127
    • Vander Lugt, B.1    Tubo, N.J.2    Nizza, S.T.3    Boes, M.4    Malissen, B.5
  • 46
    • 84872435502 scopus 로고    scopus 로고
    • Interstitial dendritic cell guidance by haptotactic chemokine gradients
    • Weber M, Hauschild R, Schwarz J, Moussion C, de Vries I, et al. 2013. Interstitial dendritic cell guidance by haptotactic chemokine gradients. Science 339:328-32
    • (2013) Science , vol.339 , pp. 328-332
    • Weber, M.1    Hauschild, R.2    Schwarz, J.3    Moussion, C.4    De Vries, I.5
  • 47
    • 84876791209 scopus 로고    scopus 로고
    • Normal dendritic cell mobilization to lymph nodes under conditions of severe lymphatic hypoplasia
    • Platt AM, Rutkowski JM, Martel C, Kuan EL, Ivanov S, et al. 2013. Normal dendritic cell mobilization to lymph nodes under conditions of severe lymphatic hypoplasia. J. Immunol. 190:4608-20
    • (2013) J. Immunol. , vol.190 , pp. 4608-4620
    • Platt, A.M.1    Rutkowski, J.M.2    Martel, C.3    Kuan, E.L.4    Ivanov, S.5
  • 48
    • 70449713917 scopus 로고    scopus 로고
    • Fluid flow regulates stromal cell organization and CCL21 expression in a tissue-engineered lymph node microenvironment
    • Tomei AA, Siegert S, Britschgi MR, Luther SA, Swartz MA. 2009. Fluid flow regulates stromal cell organization and CCL21 expression in a tissue-engineered lymph node microenvironment. J. Immunol. 183:4273-83
    • (2009) J. Immunol. , vol.183 , pp. 4273-4283
    • Tomei, A.A.1    Siegert, S.2    Britschgi, M.R.3    Luther, S.A.4    Swartz, M.A.5
  • 49
    • 0035109202 scopus 로고    scopus 로고
    • The beta-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors
    • Nibbs RJ, Kriehuber E, Ponath PD, Parent D, Qin S, et al. 2001. The beta-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors. Am. J. Pathol. 158:867-77
    • (2001) Am. J. Pathol. , vol.158 , pp. 867-877
    • Nibbs, R.J.1    Kriehuber, E.2    Ponath, P.D.3    Parent, D.4    Qin, S.5
  • 50
    • 27144437192 scopus 로고    scopus 로고
    • Silent chemoattractant receptors: D6 as a decoy and scavenger receptor for inflammatory CC chemokines
    • Locati M, Torre YM, Galliera E, Bonecchi R, Bodduluri H, et al. 2005. Silent chemoattractant receptors: D6 as a decoy and scavenger receptor for inflammatory CC chemokines. Cytokine Growth Factor Rev. 16:679-86
    • (2005) Cytokine Growth Factor Rev. , vol.16 , pp. 679-686
    • Locati, M.1    Torre, Y.M.2    Galliera, E.3    Bonecchi, R.4    Bodduluri, H.5
  • 51
    • 2342637779 scopus 로고    scopus 로고
    • The chemokine receptor D6 constitutively traffics to and from the cell surface to internalize and degrade chemokines
    • Weber M, Blair E, Simpson CV, O'Hara M, Blackburn PE, et al. 2004. The chemokine receptor D6 constitutively traffics to and from the cell surface to internalize and degrade chemokines. Mol. Biol. Cell 15:2492-508
    • (2004) Mol. Biol. Cell , vol.15 , pp. 2492-2508
    • Weber, M.1    Blair, E.2    Simpson, C.V.3    O'Hara, M.4    Blackburn, P.E.5
  • 53
    • 77149126406 scopus 로고    scopus 로고
    • The lymphatic system controls intestinal inflammation and inflammation-associated colon cancer through the chemokine decoy receptor D6
    • Vetrano S, Borroni EM, Sarukhan A, Savino B, Bonecchi R, et al. 2010. The lymphatic system controls intestinal inflammation and inflammation-associated colon cancer through the chemokine decoy receptor D6. Gut 59:197-206
    • (2010) Gut , vol.59 , pp. 197-206
    • Vetrano, S.1    Borroni, E.M.2    Sarukhan, A.3    Savino, B.4    Bonecchi, R.5
  • 54
    • 83055179249 scopus 로고    scopus 로고
    • D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestion
    • Lee KM, McKimmie CS, Gilchrist DS, Pallas KJ, Nibbs RJ, et al. 2011. D6 facilitates cellular migration and fluid flow to lymph nodes by suppressing lymphatic congestion. Blood 118:6220-29
    • (2011) Blood , vol.118 , pp. 6220-6229
    • Lee, K.M.1    McKimmie, C.S.2    Gilchrist, D.S.3    Pallas, K.J.4    Nibbs, R.J.5
  • 55
    • 84866517824 scopus 로고    scopus 로고
    • Elevated expression of the chemokinescavenging receptor D6 is associated with impaired lesion development in psoriasis
    • Singh MD, King V, Baldwin H, Burden D, Thorrat A, et al. 2012. Elevated expression of the chemokinescavenging receptor D6 is associated with impaired lesion development in psoriasis. Am. J. Pathol. 181:1158-64
    • (2012) Am. J. Pathol. , vol.181 , pp. 1158-1164
    • Singh, M.D.1    King, V.2    Baldwin, H.3    Burden, D.4    Thorrat, A.5
  • 56
    • 33847794404 scopus 로고    scopus 로고
    • Protection against inflammation-and autoantibody-caused fetal loss by the chemokine decoy receptor D6
    • Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, et al. 2007. Protection against inflammation-and autoantibody-caused fetal loss by the chemokine decoy receptor D6. PNAS 104:2319-24
    • (2007) PNAS , vol.104 , pp. 2319-2324
    • Martinez De La Torre, Y.1    Buracchi, C.2    Borroni, E.M.3    Dupor, J.4    Bonecchi, R.5
  • 57
    • 0035375108 scopus 로고    scopus 로고
    • Mouse LYVE-1 is an endocytic receptor for hyaluronan in lymphatic endothelium
    • Prevo R, Banerji S, Ferguson DJ, Clasper S, Jackson DG. 2001. Mouse LYVE-1 is an endocytic receptor for hyaluronan in lymphatic endothelium. J. Biol. Chem. 276:19420-30
    • (2001) J. Biol. Chem. , vol.276 , pp. 19420-19430
    • Prevo, R.1    Banerji, S.2    Ferguson, D.J.3    Clasper, S.4    Jackson, D.G.5
  • 58
    • 67649756857 scopus 로고    scopus 로고
    • Immunological functions of hyaluronan and its receptors in the lymphatics
    • Jackson DG. 2009. Immunological functions of hyaluronan and its receptors in the lymphatics. Immunol. Rev. 230:216-31
    • (2009) Immunol. Rev. , vol.230 , pp. 216-231
    • Jackson, D.G.1
  • 61
    • 84895541085 scopus 로고    scopus 로고
    • Hyaluronan contributes to bronchiolitis obliterans syndrome and stimulates lung allograft rejection through activation of innate immunity
    • Todd JL, Wang X, Sugimoto S, Kennedy VE, Zhang HL, et al. 2014. Hyaluronan contributes to bronchiolitis obliterans syndrome and stimulates lung allograft rejection through activation of innate immunity. Am. J. Respir. Crit. Care Med. 189:556-66
    • (2014) Am. J. Respir. Crit. Care Med. , vol.189 , pp. 556-566
    • Todd, J.L.1    Wang, X.2    Sugimoto, S.3    Kennedy, V.E.4    Zhang, H.L.5
  • 62
    • 36649033639 scopus 로고    scopus 로고
    • Lymphatic neoangiogenesis in renal transplants: A driving force of chronic rejection?
    • Kerjaschki D. 2006. Lymphatic neoangiogenesis in renal transplants: a driving force of chronic rejection? J. Nephrol. 19:403-6
    • (2006) J. Nephrol. , vol.19 , pp. 403-406
    • Kerjaschki, D.1
  • 63
    • 84946771391 scopus 로고    scopus 로고
    • Therapeutic lymphangiogenesis ameliorates established acute lung allograft rejection
    • Cui Y, Liu K, Monzon-Medina ME, Padera RF, Wang H, et al. 2015. Therapeutic lymphangiogenesis ameliorates established acute lung allograft rejection. J. Clin. Investig. 125:4255-68
    • (2015) J. Clin. Investig. , vol.125 , pp. 4255-4268
    • Cui, Y.1    Liu, K.2    Monzon-Medina, M.E.3    Padera, R.F.4    Wang, H.5
  • 64
    • 33846140150 scopus 로고    scopus 로고
    • Normal lymphatic development and function in mice deficient for the lymphatic hyaluronan receptor LYVE-1
    • Gale NW, Prevo R, Espinosa J, Ferguson DJ, Dominguez MG, et al. 2007. Normal lymphatic development and function in mice deficient for the lymphatic hyaluronan receptor LYVE-1. Mol. Cell Biol. 27:595-604
    • (2007) Mol. Cell Biol. , vol.27 , pp. 595-604
    • Gale, N.W.1    Prevo, R.2    Espinosa, J.3    Ferguson, D.J.4    Dominguez, M.G.5
  • 65
    • 84943553336 scopus 로고    scopus 로고
    • Rapid lymphatic dissemination of encapsulated group A streptococci via lymphatic vessel endothelial receptor-1 interaction
    • Lynskey NN, Banerji S, Johnson LA, Holder KA, Reglinski M, et al. 2015. Rapid lymphatic dissemination of encapsulated group A streptococci via lymphatic vessel endothelial receptor-1 interaction. PLOS Pathog. 11:e1005137
    • (2015) PLOS Pathog. , vol.11 , pp. e1005137
    • Lynskey, N.N.1    Banerji, S.2    Johnson, L.A.3    Holder, K.A.4    Reglinski, M.5
  • 66
    • 84964596025 scopus 로고    scopus 로고
    • Binding of hyaluronan to the native lymphatic vessel endothelial receptor LYVE-1 is critically dependent on receptor clustering and hyaluronan organization
    • Lawrance W, Banerji S, Day AJ, Bhattacharjee S, Jackson DG. 2016. Binding of hyaluronan to the native lymphatic vessel endothelial receptor LYVE-1 is critically dependent on receptor clustering and hyaluronan organization. J. Biol. Chem. 291:8014-30
    • (2016) J. Biol. Chem. , vol.291 , pp. 8014-8030
    • Lawrance, W.1    Banerji, S.2    Day, A.J.3    Bhattacharjee, S.4    Jackson, D.G.5
  • 67
    • 0037108377 scopus 로고    scopus 로고
    • Synthesis and surface expression of hyaluronan by dendritic cells and its potential role in antigen presentation
    • Mummert ME, Mummert D, Edelbaum D, Hui F, Matsue H, Takashima A. 2002. Synthesis and surface expression of hyaluronan by dendritic cells and its potential role in antigen presentation. J. Immunol. 169:4322-31
    • (2002) J. Immunol. , vol.169 , pp. 4322-4331
    • Mummert, M.E.1    Mummert, D.2    Edelbaum, D.3    Hui, F.4    Matsue, H.5    Takashima, A.6
  • 68
    • 33646008309 scopus 로고    scopus 로고
    • Lymphatic endothelium-specific hyaluronan receptor LYVE-1 is expressed by stabilin-1+, F4/80+,CD11b+ macrophages in malignant tumours and wound healing tissue in vivo and in bone marrow cultures in vitro: Implications for the assessment of lymphangiogenesis
    • Schledzewski K, Falkowski M, Moldenhauer G, Metharom P, Kzhyshkowska J, et al. 2006. Lymphatic endothelium-specific hyaluronan receptor LYVE-1 is expressed by stabilin-1+, F4/80+,CD11b+ macrophages in malignant tumours and wound healing tissue in vivo and in bone marrow cultures in vitro: implications for the assessment of lymphangiogenesis. J. Pathol. 209:67-77
    • (2006) J. Pathol. , vol.209 , pp. 67-77
    • Schledzewski, K.1    Falkowski, M.2    Moldenhauer, G.3    Metharom, P.4    Kzhyshkowska, J.5
  • 69
    • 33947520741 scopus 로고    scopus 로고
    • Angiogenic role of LYVE-1-positive macrophages in adipose tissue
    • Cho CH, Koh YJ, Han J, Sung HK, Jong Lee H, et al. 2007. Angiogenic role of LYVE-1-positive macrophages in adipose tissue. Circ. Res. 100:e47-57
    • (2007) Circ. Res. , vol.100 , pp. e47-57
    • Cho, C.H.1    Koh, Y.J.2    Han, J.3    Sung, H.K.4    Jong Lee, H.5
  • 70
    • 84860997131 scopus 로고    scopus 로고
    • An abundant tissuemacrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile
    • Pinto AR, Paolicelli R, Salimova E, Gospocic J, Slonimsky E, et al. 2012. An abundant tissuemacrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile. PLOS ONE 7:e36814
    • (2012) PLOS ONE , vol.7 , pp. e36814
    • Pinto, A.R.1    Paolicelli, R.2    Salimova, E.3    Gospocic, J.4    Slonimsky, E.5
  • 71
    • 84904407541 scopus 로고    scopus 로고
    • Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival
    • Gautier EL, Ivanov S, Williams JW, Huang SC, Marcelin G, et al. 2014. Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival. J. Exp. Med. 211:1525-31
    • (2014) J. Exp. Med. , vol.211 , pp. 1525-1531
    • Gautier, E.L.1    Ivanov, S.2    Williams, J.W.3    Huang, S.C.4    Marcelin, G.5
  • 72
    • 53149135427 scopus 로고    scopus 로고
    • Lymphatic precollectors contain a novel, specialized subpopulation of podoplanin low, CCL27-expressing lymphatic endothelial cells
    • Wick N, Haluza D, Gurnhofer E, Raab I, Kasimir MT, et al. 2008. Lymphatic precollectors contain a novel, specialized subpopulation of podoplanin low, CCL27-expressing lymphatic endothelial cells. Am. J. Pathol. 173:1202-9
    • (2008) Am. J. Pathol. , vol.173 , pp. 1202-1209
    • Wick, N.1    Haluza, D.2    Gurnhofer, E.3    Raab, I.4    Kasimir, M.T.5
  • 73
    • 84929630968 scopus 로고    scopus 로고
    • Collecting lymphatic vessel permeability facilitates adipose tissue inflammation and distribution of antigen to lymph node-homing adipose tissue dendritic cells
    • Kuan EL, Ivanov S, Bridenbaugh EA, Victora G, Wang W, et al. 2015. Collecting lymphatic vessel permeability facilitates adipose tissue inflammation and distribution of antigen to lymph node-homing adipose tissue dendritic cells. J. Immunol. 194:5200-10
    • (2015) J. Immunol. , vol.194 , pp. 5200-5210
    • Kuan, E.L.1    Ivanov, S.2    Bridenbaugh, E.A.3    Victora, G.4    Wang, W.5
  • 74
    • 0025076869 scopus 로고
    • Microlymphatics and lymph flow
    • Schmid-Schonbein GW. 1990. Microlymphatics and lymph flow. Physiol. Rev. 70:987-1028
    • (1990) Physiol. Rev. , vol.70 , pp. 987-1028
    • Schmid-Schonbein, G.W.1
  • 77
    • 84878254278 scopus 로고    scopus 로고
    • Involvement of the NO-cGMP-K(ATP) channel pathway in the mesenteric lymphatic pump dysfunction observed in the Guinea pig model of TNBS-induced ileitis
    • Mathias R, von der Weid PY. 2013. Involvement of the NO-cGMP-K(ATP) channel pathway in the mesenteric lymphatic pump dysfunction observed in the guinea pig model of TNBS-induced ileitis. Am. J. Physiol. Gastrointest. Liver Physiol. 304:G623-34
    • (2013) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.304 , pp. G623-G634
    • Mathias, R.1    Von Der Weid, P.Y.2
  • 79
    • 34948856826 scopus 로고    scopus 로고
    • Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature
    • Srinivasan RS, Dillard ME, Lagutin OV, Lin FJ, Tsai S, et al. 2007. Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev. 21:2422-32
    • (2007) Genes Dev. , vol.21 , pp. 2422-2432
    • Srinivasan, R.S.1    Dillard, M.E.2    Lagutin, O.V.3    Lin, F.J.4    Tsai, S.5
  • 80
    • 84964671780 scopus 로고    scopus 로고
    • CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability
    • Ivanov S, Scallan JP, Kim KW, Werth K, Johnson MW, et al. 2016. CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability. J. Clin. Investig. 126:1581-91
    • (2016) J. Clin. Investig. , vol.126 , pp. 1581-1591
    • Ivanov, S.1    Scallan, J.P.2    Kim, K.W.3    Werth, K.4    Johnson, M.W.5
  • 81
    • 4644362609 scopus 로고    scopus 로고
    • Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis
    • Petrova TV, Karpanen T, Norrmen C, Mellor R, Tamakoshi T, et al. 2004. Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis. Nat. Med. 10:974-81
    • (2004) Nat. Med. , vol.10 , pp. 974-981
    • Petrova, T.V.1    Karpanen, T.2    Norrmen, C.3    Mellor, R.4    Tamakoshi, T.5
  • 82
    • 34247168398 scopus 로고    scopus 로고
    • Mutations in FOXC2 are strongly associated with primary valve failure in veins of the lower limb
    • Mellor RH, Brice G, Stanton AW, French J, Smith A, et al. 2007. Mutations in FOXC2 are strongly associated with primary valve failure in veins of the lower limb. Circulation 115:1912-20
    • (2007) Circulation , vol.115 , pp. 1912-1920
    • Mellor, R.H.1    Brice, G.2    Stanton, A.W.3    French, J.4    Smith, A.5
  • 84
    • 84886996913 scopus 로고    scopus 로고
    • EMILIN1/α9β1 integrin interaction is crucial in lymphatic valve formation and maintenance
    • Danussi C, Del Bel Belluz L, Pivetta E, Modica TM, Muro A, et al. 2013. EMILIN1/α9β1 integrin interaction is crucial in lymphatic valve formation and maintenance. Mol. Cell Biol. 33:4381-94
    • (2013) Mol. Cell Biol. , vol.33 , pp. 4381-4394
    • Danussi, C.1    Del Bel Belluz, L.2    Pivetta, E.3    Modica, T.M.4    Muro, A.5
  • 86
    • 84872381267 scopus 로고    scopus 로고
    • Constriction of isolated collecting lymphatic vessels in response to acute increases in downstream pressure
    • Scallan JP, Wolpers JH, Davis MJ. 2013. Constriction of isolated collecting lymphatic vessels in response to acute increases in downstream pressure. J. Physiol. 591:443-59
    • (2013) J. Physiol. , vol.591 , pp. 443-459
    • Scallan, J.P.1    Wolpers, J.H.2    Davis, M.J.3
  • 87
    • 84907203122 scopus 로고    scopus 로고
    • Involvement of histamine in endothelium-dependent relaxation of mesenteric lymphatic vessels
    • Nizamutdinova IT, Maejima D, Nagai T, Bridenbaugh E, Thangaswamy S, et al. 2014. Involvement of histamine in endothelium-dependent relaxation of mesenteric lymphatic vessels. Microcirculation 21:640-48
    • (2014) Microcirculation , vol.21 , pp. 640-648
    • Nizamutdinova, I.T.1    Maejima, D.2    Nagai, T.3    Bridenbaugh, E.4    Thangaswamy, S.5
  • 88
    • 84908209056 scopus 로고    scopus 로고
    • Involvement of H1 and H2 receptors and soluble guanylate cyclase in histamine-induced relaxation of rat mesenteric collecting lymphatics
    • Kurtz KH, Moor AN, Souza-Smith FM, Breslin JW. 2014. Involvement of H1 and H2 receptors and soluble guanylate cyclase in histamine-induced relaxation of rat mesenteric collecting lymphatics. Microcirculation 21:593-605
    • (2014) Microcirculation , vol.21 , pp. 593-605
    • Kurtz, K.H.1    Moor, A.N.2    Souza-Smith, F.M.3    Breslin, J.W.4
  • 89
    • 0036588491 scopus 로고    scopus 로고
    • Inhibition of the active lymph pump by flow in ratmesenteric lymphatics and thoracic duct
    • Gashev AA, Davis MJ, Zawieja DC. 2002. Inhibition of the active lymph pump by flow in ratmesenteric lymphatics and thoracic duct. J. Physiol. 540:1023-37
    • (2002) J. Physiol. , vol.540 , pp. 1023-1037
    • Gashev, A.A.1    Davis, M.J.2    Zawieja, D.C.3
  • 90
    • 81755186998 scopus 로고    scopus 로고
    • Impaired lymphatic contraction associated with immunosuppression
    • Liao S, Cheng G, Conner DA, Huang Y, Kucherlapati RS, et al. 2011. Impaired lymphatic contraction associated with immunosuppression. PNAS 108:18784-89
    • (2011) PNAS , vol.108 , pp. 18784-18789
    • Liao, S.1    Cheng, G.2    Conner, D.A.3    Huang, Y.4    Kucherlapati, R.S.5
  • 91
    • 84876319324 scopus 로고    scopus 로고
    • Genetic removal of basal nitric oxide enhances contractile activity in isolated murine collecting lymphatic vessels
    • Scallan JP, Davis MJ. 2013. Genetic removal of basal nitric oxide enhances contractile activity in isolated murine collecting lymphatic vessels. J. Physiol. 591:2139-56
    • (2013) J. Physiol. , vol.591 , pp. 2139-2156
    • Scallan, J.P.1    Davis, M.J.2
  • 92
    • 84896055340 scopus 로고    scopus 로고
    • In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice
    • Bouta EM, Wood RW, Brown EB, Rahimi H, Ritchlin CT, Schwarz EM. 2014. In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice. J. Physiol. 592:1213-23
    • (2014) J. Physiol. , vol.592 , pp. 1213-1223
    • Bouta, E.M.1    Wood, R.W.2    Brown, E.B.3    Rahimi, H.4    Ritchlin, C.T.5    Schwarz, E.M.6
  • 93
    • 78049518356 scopus 로고    scopus 로고
    • Chemoattractant receptors and lymphocyte egress from extralymphoid tissue: Changing requirements during the course of inflammation
    • Brown MN, Fintushel SR, Lee MH, Jennrich S, Geherin SA, et al. 2010. Chemoattractant receptors and lymphocyte egress from extralymphoid tissue: changing requirements during the course of inflammation. J. Immunol. 185:4873-82
    • (2010) J. Immunol. , vol.185 , pp. 4873-4882
    • Brown, M.N.1    Fintushel, S.R.2    Lee, M.H.3    Jennrich, S.4    Geherin, S.A.5
  • 95
    • 0028895941 scopus 로고
    • Endotoxin-mediated dendritic cell release from the intestine: Characterization of released dendritic cells and TNF dependence
    • MacPherson GG, Jenkins CD, Stein MJ, Edwards C. 1995. Endotoxin-mediated dendritic cell release from the intestine: characterization of released dendritic cells and TNF dependence. J. Immunol. 154:1317-22
    • (1995) J. Immunol. , vol.154 , pp. 1317-1322
    • MacPherson, G.G.1    Jenkins, C.D.2    Stein, M.J.3    Edwards, C.4
  • 96
    • 84902662442 scopus 로고    scopus 로고
    • The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes
    • Ulvmar MH, Werth K, Braun A, Kelay P, Hub E, et al. 2014. The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes. Nat. Immunol. 15:623-30
    • (2014) Nat. Immunol. , vol.15 , pp. 623-630
    • Ulvmar, M.H.1    Werth, K.2    Braun, A.3    Kelay, P.4    Hub, E.5
  • 97
    • 9244240285 scopus 로고    scopus 로고
    • Role of CCR8 and other chemokine pathways in themigration of monocyte-derived dendritic cells to lymph nodes
    • Qu C, Edwards EW, Tacke F, Angeli V, Llodra J, et al. 2004. Role of CCR8 and other chemokine pathways in themigration of monocyte-derived dendritic cells to lymph nodes. J. Exp. Med. 200:1231-41
    • (2004) J. Exp. Med. , vol.200 , pp. 1231-1241
    • Qu, C.1    Edwards, E.W.2    Tacke, F.3    Angeli, V.4    Llodra, J.5
  • 98
    • 84883192541 scopus 로고    scopus 로고
    • Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses
    • Das S, Sarrou E, Podgrabinska S, Cassella M, Mungamuri SK, et al. 2013. Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses. J. Exp. Med. 210:1509-28
    • (2013) J. Exp. Med. , vol.210 , pp. 1509-1528
    • Das, S.1    Sarrou, E.2    Podgrabinska, S.3    Cassella, M.4    Mungamuri, S.K.5
  • 99
    • 84925396037 scopus 로고    scopus 로고
    • The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes
    • Rantakari P, Auvinen K, Jappinen N, Kapraali M, Valtonen J, et al. 2015. The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes. Nat. Immunol. 16:386-96
    • (2015) Nat. Immunol. , vol.16 , pp. 386-396
    • Rantakari, P.1    Auvinen, K.2    Jappinen, N.3    Kapraali, M.4    Valtonen, J.5
  • 100
    • 76149126108 scopus 로고    scopus 로고
    • Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning
    • Pham TH, Baluk P, Xu Y, Grigorova I, Bankovich AJ, et al. 2010. Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning. J. Exp. Med. 207:17-27
    • (2010) J. Exp. Med. , vol.207 , pp. 17-27
    • Pham, T.H.1    Baluk, P.2    Xu, Y.3    Grigorova, I.4    Bankovich, A.J.5
  • 101
    • 33645289121 scopus 로고    scopus 로고
    • CD69 acts downstream of interferonalpha/ beta to inhibit S1P1 and lymphocyte egress from lymphoid organs
    • Shiow LR, Rosen DB, Brdickova N, Xu Y, An J, et al. 2006. CD69 acts downstream of interferonalpha/ beta to inhibit S1P1 and lymphocyte egress from lymphoid organs. Nature 440:540-44
    • (2006) Nature , vol.440 , pp. 540-544
    • Shiow, L.R.1    Rosen, D.B.2    Brdickova, N.3    Xu, Y.4    An, J.5
  • 102
    • 32244443955 scopus 로고    scopus 로고
    • B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization
    • Angeli V, Ginhoux F, Llodra J, Quemeneur L, Frenette PS, et al. 2006. B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity 24:203-15
    • (2006) Immunity , vol.24 , pp. 203-215
    • Angeli, V.1    Ginhoux, F.2    Llodra, J.3    Quemeneur, L.4    Frenette, P.S.5
  • 103
    • 84860320665 scopus 로고    scopus 로고
    • Expansion of cortical and medullary sinuses restrains lymph node hypertrophy during prolonged inflammation
    • Tan KW, Yeo KP, Wong FH, Lim HY, Khoo KL, et al. 2012. Expansion of cortical and medullary sinuses restrains lymph node hypertrophy during prolonged inflammation. J. Immunol. 188:4065-80
    • (2012) J. Immunol. , vol.188 , pp. 4065-4080
    • Tan, K.W.1    Yeo, K.P.2    Wong, F.H.3    Lim, H.Y.4    Khoo, K.L.5
  • 104
    • 84892516740 scopus 로고    scopus 로고
    • Neutrophils contribute to inflammatory lymphangiogenesis by increasing VEGF-A bioavailability and secreting VEGF-D
    • Tan KW, Chong SZ, Wong FH, Evrard M, Tan SM, et al. 2013. Neutrophils contribute to inflammatory lymphangiogenesis by increasing VEGF-A bioavailability and secreting VEGF-D. Blood 122:3666-77
    • (2013) Blood , vol.122 , pp. 3666-3677
    • Tan, K.W.1    Chong, S.Z.2    Wong, F.H.3    Evrard, M.4    Tan, S.M.5
  • 105
    • 78751688024 scopus 로고    scopus 로고
    • T lymphocytes negatively regulate lymph node lymphatic vessel formation
    • Kataru RP, Kim H, Jang C, Choi DK, Koh BI, et al. 2011. T lymphocytes negatively regulate lymph node lymphatic vessel formation. Immunity 34:96-107
    • (2011) Immunity , vol.34 , pp. 96-107
    • Kataru, R.P.1    Kim, H.2    Jang, C.3    Choi, D.K.4    Koh, B.I.5
  • 106
    • 84897491341 scopus 로고    scopus 로고
    • Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment
    • Cohen JN, Tewalt EF, Rouhani SJ, Buonomo EL, Bruce AN, et al. 2014. Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment. PLOS ONE 9:e87740
    • (2014) PLOS ONE , vol.9 , pp. e87740
    • Cohen, J.N.1    Tewalt, E.F.2    Rouhani, S.J.3    Buonomo, E.L.4    Bruce, A.N.5
  • 107
    • 84899631225 scopus 로고    scopus 로고
    • Mapping the distinctive populations of lymphatic endothelial cells in different zones of human lymph nodes
    • Park SM, Angel CE, McIntosh JD, Mansell C, Chen CJ, et al. 2014. Mapping the distinctive populations of lymphatic endothelial cells in different zones of human lymph nodes. PLOS ONE 9:e94781
    • (2014) PLOS ONE , vol.9 , pp. e94781
    • Park, S.M.1    Angel, C.E.2    McIntosh, J.D.3    Mansell, C.4    Chen, C.J.5
  • 108
    • 77951069509 scopus 로고    scopus 로고
    • Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
    • Cohen JN, Guidi CJ, Tewalt EF, Qiao H, Rouhani SJ, et al. 2010. Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation. J. Exp. Med. 207:681-88
    • (2010) J. Exp. Med. , vol.207 , pp. 681-688
    • Cohen, J.N.1    Guidi, C.J.2    Tewalt, E.F.3    Qiao, H.4    Rouhani, S.J.5
  • 109
    • 84919835281 scopus 로고    scopus 로고
    • Stromal infrastructure of the lymph node and coordination of immunity
    • Chang JE, Turley SJ. 2015. Stromal infrastructure of the lymph node and coordination of immunity. Trends Immunol. 36:30-39
    • (2015) Trends Immunol. , vol.36 , pp. 30-39
    • Chang, J.E.1    Turley, S.J.2
  • 110
    • 84901247776 scopus 로고    scopus 로고
    • Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: A new role for lymphatic endothelial cells
    • Hirosue S, Vokali E, Raghavan VR, Rincon-Restrepo M, Lund AW, et al. 2014. Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells. J. Immunol. 192:5002-11
    • (2014) J. Immunol. , vol.192 , pp. 5002-5011
    • Hirosue, S.1    Vokali, E.2    Raghavan, V.R.3    Rincon-Restrepo, M.4    Lund, A.W.5
  • 111
    • 84902196240 scopus 로고    scopus 로고
    • Antigen capture and archiving by lymphatic endothelial cells following vaccination or viral infection
    • Tamburini BA, Burchill MA, Kedl RM. 2014. Antigen capture and archiving by lymphatic endothelial cells following vaccination or viral infection. Nat. Commun. 5:3989
    • (2014) Nat. Commun. , vol.5 , pp. 3989
    • Tamburini, B.A.1    Burchill, M.A.2    Kedl, R.M.3
  • 112
    • 84859926294 scopus 로고    scopus 로고
    • Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks
    • Malhotra D, Fletcher AL, Astarita J, Lukacs-Kornek V, Tayalia P, et al. 2012. Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks. Nat. Immunol. 13:499-510
    • (2012) Nat. Immunol. , vol.13 , pp. 499-510
    • Malhotra, D.1    Fletcher, A.L.2    Astarita, J.3    Lukacs-Kornek, V.4    Tayalia, P.5
  • 114
    • 84901745244 scopus 로고    scopus 로고
    • Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4+ T cell tolerance
    • Dubrot J, Duraes FV, Potin L, Capotosti F, Brighouse D, et al. 2014. Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4+ T cell tolerance. J. Exp. Med. 211:1153-66
    • (2014) J. Exp. Med. , vol.211 , pp. 1153-1166
    • Dubrot, J.1    Duraes, F.V.2    Potin, L.3    Capotosti, F.4    Brighouse, D.5
  • 115
    • 85018263978 scopus 로고    scopus 로고
    • Contraction of the hypertrophic lymph node and death of lymphatic endothelial cells as a process for antigen exchange
    • Mar. 22, Ventura, CA
    • Kedl R, Finlon J, Tamburini B. 2016. Contraction of the hypertrophic lymph node and death of lymphatic endothelial cells as a process for antigen exchange. Presented at Lymphat. Gordon Res. Conf., Mar. 22, Ventura, CA
    • (2016) Lymphat. Gordon Res. Conf
    • Kedl, R.1    Finlon, J.2    Tamburini, B.3
  • 116
    • 84867740805 scopus 로고    scopus 로고
    • Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
    • Gautier EL, Shay T, Miller J, Greter M, Jakubzick C, et al. 2012. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat. Immunol. 13:1118-28
    • (2012) Nat. Immunol. , vol.13 , pp. 1118-1128
    • Gautier, E.L.1    Shay, T.2    Miller, J.3    Greter, M.4    Jakubzick, C.5
  • 117
    • 84870733775 scopus 로고    scopus 로고
    • IL-7-producing stromal cells are critical for lymph node remodeling
    • Onder L, Narang P, Scandella E, Chai Q, Iolyeva M, et al. 2012. IL-7-producing stromal cells are critical for lymph node remodeling. Blood 120:4675-83
    • (2012) Blood , vol.120 , pp. 4675-4683
    • Onder, L.1    Narang, P.2    Scandella, E.3    Chai, Q.4    Iolyeva, M.5
  • 118
    • 84881090860 scopus 로고    scopus 로고
    • IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia
    • Miller CN, Hartigan-O'Connor DJ, Lee MS, Laidlaw G, Cornelissen IP, et al. 2013. IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia. Int. Immunol. 25:471-83
    • (2013) Int. Immunol. , vol.25 , pp. 471-483
    • Miller, C.N.1    Hartigan-O'Connor, D.J.2    Lee, M.S.3    Laidlaw, G.4    Cornelissen, I.P.5
  • 119
    • 84864808073 scopus 로고    scopus 로고
    • Identification of IL-7-producing cells in primary and secondary lymphoid organs using IL-7-GFP knock-in mice
    • Hara T, Shitara S, Imai K, Miyachi H, Kitano S, et al. 2012. Identification of IL-7-producing cells in primary and secondary lymphoid organs using IL-7-GFP knock-in mice. J. Immunol. 189:1577-84
    • (2012) J. Immunol. , vol.189 , pp. 1577-1584
    • Hara, T.1    Shitara, S.2    Imai, K.3    Miyachi, H.4    Kitano, S.5
  • 120
    • 84969822517 scopus 로고    scopus 로고
    • Thy1+IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation
    • Shinoda K, Hirahara K, Iinuma T, Ichikawa T, Suzuki AS, et al. 2016. Thy1+IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation. PNAS 113:E2842-51
    • (2016) PNAS , vol.113 , pp. E2842-E2851
    • Shinoda, K.1    Hirahara, K.2    Iinuma, T.3    Ichikawa, T.4    Suzuki, A.S.5
  • 122
    • 0020189435 scopus 로고
    • Quantitation of changes in lymph protein concentration during lymph node transit
    • Adair TH, Moffatt DS, Paulsen AW, Guyton AC. 1982. Quantitation of changes in lymph protein concentration during lymph node transit. Am. J. Physiol. 243:H351-59
    • (1982) Am. J. Physiol. , vol.243 , pp. H351-H359
    • Adair, T.H.1    Moffatt, D.S.2    Paulsen, A.W.3    Guyton, A.C.4
  • 123
    • 84892923313 scopus 로고    scopus 로고
    • Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life
    • Hess PR, Rawnsley DR, Jakus Z, Yang Y, Sweet DT, et al. 2014. Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life. J. Clin. Investig. 124:273-84
    • (2014) J. Clin. Investig. , vol.124 , pp. 273-284
    • Hess, P.R.1    Rawnsley, D.R.2    Jakus, Z.3    Yang, Y.4    Sweet, D.T.5
  • 125
    • 84865424661 scopus 로고    scopus 로고
    • Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage
    • Thomas SN, Rutkowski JM, Pasquier M, Kuan EL, Alitalo K, et al. 2012. Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage. J. Immunol. 189:2181-90
    • (2012) J. Immunol. , vol.189 , pp. 2181-2190
    • Thomas, S.N.1    Rutkowski, J.M.2    Pasquier, M.3    Kuan, E.L.4    Alitalo, K.5
  • 127
    • 0000807038 scopus 로고
    • Pathology of regional ileitis and ulcerative colitis
    • Warren S, Sommers SC. 1954. Pathology of regional ileitis and ulcerative colitis. J. Am. Med. Assoc. 154:189-93
    • (1954) J. Am. Med. Assoc. , vol.154 , pp. 189-193
    • Warren, S.1    Sommers, S.C.2
  • 129
    • 84938244327 scopus 로고    scopus 로고
    • Small molecules from the human microbiota
    • Donia MS, Fischbach MA. 2015. Small molecules from the human microbiota. Science 349:1254766
    • (2015) Science , vol.349 , pp. 1254766
    • Donia, M.S.1    Fischbach, M.A.2
  • 130
    • 41149092188 scopus 로고    scopus 로고
    • The 10 remaining mysteries of inflammatory bowel disease
    • Colombel JF, Watson AJ, Neurath MF. 2008. The 10 remaining mysteries of inflammatory bowel disease. Gut 57:429-33
    • (2008) Gut , vol.57 , pp. 429-433
    • Colombel, J.F.1    Watson, A.J.2    Neurath, M.F.3
  • 132
    • 84943653785 scopus 로고    scopus 로고
    • Microbiota-dependent sequelae of acute infection compromise tissue-specific immunity
    • Fonseca DM, Hand TW, Han SJ, Gerner MY, Glatman Zaretsky A, et al. 2015. Microbiota-dependent sequelae of acute infection compromise tissue-specific immunity. Cell 163:354-66
    • (2015) Cell , vol.163 , pp. 354-366
    • Fonseca, D.M.1    Hand, T.W.2    Han, S.J.3    Gerner, M.Y.4    Glatman Zaretsky, A.5
  • 133
    • 73549098183 scopus 로고    scopus 로고
    • In vivo determination of collecting lymphatic vessel permeability to albumin: A role for lymphatics in exchange
    • Scallan JP, Huxley VH. 2010. In vivo determination of collecting lymphatic vessel permeability to albumin: a role for lymphatics in exchange. J. Physiol. 588:243-54
    • (2010) J. Physiol. , vol.588 , pp. 243-254
    • Scallan, J.P.1    Huxley, V.H.2
  • 134
    • 78651500757 scopus 로고    scopus 로고
    • Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORγt and LTi cells
    • Lochner M, Ohnmacht C, Presley L, Bruhns P, Si-Tahar M, et al. 2011. Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORγt and LTi cells. J. Exp. Med. 208:125-34
    • (2011) J. Exp. Med. , vol.208 , pp. 125-134
    • Lochner, M.1    Ohnmacht, C.2    Presley, L.3    Bruhns, P.4    Si-Tahar, M.5
  • 135
    • 84883551247 scopus 로고    scopus 로고
    • Cytokines are systemic effectors of lymphatic function in acute inflammation
    • Aldrich MB, Sevick-Muraca EM. 2013. Cytokines are systemic effectors of lymphatic function in acute inflammation. Cytokine 64:362-69
    • (2013) Cytokine , vol.64 , pp. 362-369
    • Aldrich, M.B.1    Sevick-Muraca, E.M.2
  • 136
    • 84970016693 scopus 로고    scopus 로고
    • Putative role of the H+/sucrose symporter SLC45A3 as an osmolyte transporter in the kidney
    • Vitavska O, Edemir B, Wieczorek H. 2016. Putative role of the H+/sucrose symporter SLC45A3 as an osmolyte transporter in the kidney. Pflugers Arch. 468:1353-62
    • (2016) Pflugers Arch. , vol.468 , pp. 1353-1362
    • Vitavska, O.1    Edemir, B.2    Wieczorek, H.3
  • 137
    • 84924364443 scopus 로고    scopus 로고
    • Tissue sodium storage: Evidence for kidney-like extrarenal countercurrent systems?
    • Hofmeister LH, Perisic S, Titze J. 2015. Tissue sodium storage: evidence for kidney-like extrarenal countercurrent systems? Pflugers Arch. 467:551-58
    • (2015) Pflugers Arch. , vol.467 , pp. 551-558
    • Hofmeister, L.H.1    Perisic, S.2    Titze, J.3
  • 138
    • 84857860678 scopus 로고    scopus 로고
    • Popeye proteins: Muscle for the aging sinus node
    • Boukens BJ, Christoffels VM. 2012. Popeye proteins: muscle for the aging sinus node. J. Clin. Investig. 122:810-13
    • (2012) J. Clin. Investig. , vol.122 , pp. 810-813
    • Boukens, B.J.1    Christoffels, V.M.2
  • 139
    • 84958525789 scopus 로고    scopus 로고
    • Transcriptional control of lymphatic endothelial cell type specification
    • Yang Y, Oliver G. 2014. Transcriptional control of lymphatic endothelial cell type specification. Adv. Anat. Embryol. Cell Biol. 214:5-22
    • (2014) Adv. Anat. Embryol. Cell Biol. , vol.214 , pp. 5-22
    • Yang, Y.1    Oliver, G.2
  • 140
    • 0037238131 scopus 로고    scopus 로고
    • The lymphatics revisited: New perspectives from the hyaluronan receptor LYVE-1
    • Jackson DG. 2003. The lymphatics revisited: new perspectives from the hyaluronan receptor LYVE-1. Trends Cardiovasc. Med. 13:1-7
    • (2003) Trends Cardiovasc. Med. , vol.13 , pp. 1-7
    • Jackson, D.G.1
  • 141
    • 0032937233 scopus 로고    scopus 로고
    • Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: Podoplanin as a specific marker for lymphatic endothelium
    • Breiteneder-Geleff S, Soleiman A, Kowalski H, Horvat R, Amann G, et al. 1999. Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium. Am. J. Pathol. 154:385-94
    • (1999) Am. J. Pathol. , vol.154 , pp. 385-394
    • Breiteneder-Geleff, S.1    Soleiman, A.2    Kowalski, H.3    Horvat, R.4    Amann, G.5
  • 142
    • 76749148097 scopus 로고    scopus 로고
    • Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation
    • Uhrin P, Zaujec J, Breuss JM, Olcaydu D, Chrenek P, et al. 2010. Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation. Blood 115:3997-4005
    • (2010) Blood , vol.115 , pp. 3997-4005
    • Uhrin, P.1    Zaujec, J.2    Breuss, J.M.3    Olcaydu, D.4    Chrenek, P.5
  • 143
    • 0034800455 scopus 로고    scopus 로고
    • Is the class A macrophage scavenger receptor (SR-A) multifunctional? the mouse's tale
    • Platt N, Gordon S. 2001. Is the class A macrophage scavenger receptor (SR-A) multifunctional? The mouse's tale. J. Clin. Investig. 108:649-54
    • (2001) J. Clin. Investig. , vol.108 , pp. 649-654
    • Platt, N.1    Gordon, S.2
  • 144
    • 47749130000 scopus 로고    scopus 로고
    • The human hyaluronan receptor for endocytosis (HARE/Stabilin-2) is a systemic clearance receptor for heparin
    • Harris EN, Weigel JA, Weigel PH. 2008. The human hyaluronan receptor for endocytosis (HARE/Stabilin-2) is a systemic clearance receptor for heparin. J. Biol. Chem. 283:17341-50
    • (2008) J. Biol. Chem. , vol.283 , pp. 17341-17350
    • Harris, E.N.1    Weigel, J.A.2    Weigel, P.H.3
  • 145
    • 84864874616 scopus 로고    scopus 로고
    • An unexpected role of semaphorin3A-neuropilin-1 signaling in lymphatic vessel maturation and valve formation
    • Jurisic G, Maby-El Hajjami H, Karaman S, Ochsenbein AM, Alitalo A, et al. 2012. An unexpected role of semaphorin3A-neuropilin-1 signaling in lymphatic vessel maturation and valve formation. Circ. Res. 111:426-36
    • (2012) Circ. Res. , vol.111 , pp. 426-436
    • Jurisic, G.1    Maby-El Hajjami, H.2    Karaman, S.3    Ochsenbein, A.M.4    Alitalo, A.5
  • 146
    • 84954535412 scopus 로고    scopus 로고
    • Actin-andmicrotubule-dependent regulation ofGolgi morphology by FHDC1
    • Copeland SJ, Thurston SF, Copeland JW. 2016. Actin-andmicrotubule-dependent regulation ofGolgi morphology by FHDC1. Mol. Biol. Cell 27:260-76
    • (2016) Mol. Biol. Cell , vol.27 , pp. 260-276
    • Copeland, S.J.1    Thurston, S.F.2    Copeland, J.W.3
  • 147
    • 0021258827 scopus 로고
    • Modification of lymphocyte traffic by vasoactive neurotransmitter substances
    • Moore TC. 1984. Modification of lymphocyte traffic by vasoactive neurotransmitter substances. Immunology 52:511-18
    • (1984) Immunology , vol.52 , pp. 511-518
    • Moore, T.C.1
  • 148
    • 84935472292 scopus 로고    scopus 로고
    • Filopodia formation driven by membrane glycoprotein M6a depends on the interaction of its transmembrane domains
    • Formoso K, Garcia MD, Frasch AC, Scorticati C. 2015. Filopodia formation driven by membrane glycoprotein M6a depends on the interaction of its transmembrane domains. J. Neurochem. 134:499-512
    • (2015) J. Neurochem. , vol.134 , pp. 499-512
    • Formoso, K.1    Garcia, M.D.2    Frasch, A.C.3    Scorticati, C.4


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