Erratum: The Spleen in Local and Systemic Regulation of Immunity (The Spleen in Local and Systemic Regulation of Immunity (2013) 39(5) (806–818), (S1074761313004706), (10.1016/j.immuni.2013.10.010));The spleen in local and systemic regulation of immunity

Immunity

Volumn 39, Issue 5, 2013, Pages 806-818

  Bronte, Vincenzo ^a   Pittet, Mikael J ^b  

^a UNIVERSITY HOSPITAL OF VERONA   (Italy)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; CHEMOKINE RECEPTOR CXCR5; CXCL13 CHEMOKINE; CYCLOPHOSPHAMIDE; ENALAPRIL; FLUDARABINE; FLUOROURACIL; GEMCITABINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 3; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; SORAFENIB; SPHINGOSINE 1 PHOSPHATE; SUNITINIB; TRANSFORMING GROWTH FACTOR BETA; VERY LATE ACTIVATION ANTIGEN 4; ANGIOTENSIN II; ANTINEOPLASTIC AGENT;

ADAPTIVE IMMUNITY; ANTIGEN PRESENTATION; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL FATE; CELL MOTILITY; CELL STRESS; CYTOTOXIC T LYMPHOCYTE; EXTRAMEDULLARY HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; MONONUCLEAR PHAGOCYTE; NATURAL KILLER T CELL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; REVIEW; SPLEEN; SPLEEN CELL; SPLENECTOMY; SPLENOMEGALY; TUMOR ASSOCIATED LEUKOCYTE; ADOPTIVE IMMUNOTHERAPY; ANIMAL; APOPTOSIS; BIOLOGICAL MODEL; CELL DIFFERENTIATION; CELL LINEAGE; CYTOLOGY; DRUG DELIVERY SYSTEM; IMMUNOLOGY; INFLAMMATION; INNATE IMMUNITY; LYMPHOCYTE SUBPOPULATION; MOUSE; NEOPLASM; PHAGOCYTE; PHYSIOLOGY; SPECIES DIFFERENCE;

ADAPTIVE IMMUNITY; ANGIOTENSIN II; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIFFERENTIATION; CELL LINEAGE; DRUG DELIVERY SYSTEMS; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNE TOLERANCE; IMMUNITY, INNATE; IMMUNOTHERAPY, ADOPTIVE; INFLAMMATION; LYMPHOCYTE SUBSETS; MICE; MODELS, IMMUNOLOGICAL; NEOPLASMS; PHAGOCYTES; SPECIES SPECIFICITY; SPLEEN;

EID: 84887524207     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2023.04.004     Document Type: Erratum

References (120)

1. A-Gonzalez N., Bensinger S.J., Hong C., Beceiro S., Bradley M.N., Zelcer N., Deniz J., Ramirez C., Díaz M., Gallardo G., et al. Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR. Immunity 2009, 31:245-258.
2. A-Gonzalez N., Guillen J.A., Gallardo G., Diaz M., de la Rosa J.V., Hernandez I.H., Casanova-Acebes M., Lopez F., Tabraue C., Beceiro S., et al. The nuclear receptor LXRα controls the functional specialization of splenic macrophages. Nat. Immunol. 2013, 14:831-839.
3. Amlot P.L., Hayes A.E. Impaired human antibody response to the thymus-independent antigen, DNP-Ficoll, after splenectomy. Implications for post-splenectomy infections. Lancet 1985, 1:1008-1011.
4. Ansel K.M., Ngo V.N., Hyman P.L., Luther S.A., Förster R., Sedgwick J.D., Browning J.L., Lipp M., Cyster J.G. A chemokine-driven positive feedback loop organizes lymphoid follicles. Nature 2000, 406:309-314.
5. Arnon T.I., Xu Y., Lo C., Pham T., An J., Coughlin S., Dorn G.W., Cyster J.G. GRK2-dependent S1PR1 desensitization is required for lymphocytes to overcome their attraction to blood. Science 2011, 333:1898-1903.
6. Arnon T.I., Horton R.M., Grigorova I.L., Cyster J.G. Visualization of splenic marginal zone B-cell shuttling and follicular B-cell egress. Nature 2013, 493:684-688.
7. Auffray C., Fogg D.K., Narni-Mancinelli E., Senechal B., Trouillet C., Saederup N., Leemput J., Bigot K., Campisi L., Abitbol M., et al. CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation. J.Exp. Med. 2009, 206:595-606.
8. Barral P., Sánchez-Niño M.D., van Rooijen N., Cerundolo V., Batista F.D. The location of splenic NKT cells favours their rapid activation by blood-borne antigen. EMBO J. 2012, 31:2378-2390.
9. Bayne L.J., Beatty G.L., Jhala N., Clark C.E., Rhim A.D., Stanger B.Z., Vonderheide R.H. Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and Tcell immunity in pancreatic cancer. Cancer Cell 2012, 21:822-835.
10. Bonnefoy F., Perruche S., Couturier M., Sedrati A., Sun Y., Tiberghien P., Gaugler B., Saas P. Plasmacytoid dendritic cells play a major role in apoptotic leukocyte-induced immune modulation. J.Immunol. 2011, 186:5696-5705.
11. Bronte V., Apolloni E., Cabrelle A., Ronca R., Serafini P., Zamboni P., Restifo N.P., Zanovello P. Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) Tcells. Blood 2000, 96:3838-3846.
12. Buettner M., Bornemann M., Bode U. Skin tolerance is supported by the spleen. Scand. J. Immunol. 2013, 77:238-245.
13. Cadili A., de Gara C. Complications of splenectomy. Am. J. Med. 2008, 121:371-375.
14. Cheong C., Matos I., Choi J.H., Dandamudi D.B., Shrestha E., Longhi M.P., Jeffrey K.L., Anthony R.M., Kluger C., Nchinda G., et al. Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune Tcell areas. Cell 2010, 143:416-429.
15. Chotivanich K., Udomsangpetch R., McGready R., Proux S., Newton P., Pukrittayakamee S., Looareesuwan S., White N.J. Central role of the spleen in malaria parasite clearance. J.Infect. Dis. 2002, 185:1538-1541.
16. Cinamon G., Matloubian M., Lesneski M.J., Xu Y., Low C., Lu T., Proia R.L., Cyster J.G. Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone. Nat. Immunol. 2004, 5:713-720.
17. Cortez-Retamozo V., Etzrodt M., Newton A., Rauch P.J., Chudnovskiy A., Berger C., Ryan R.J., Iwamoto Y., Marinelli B., Gorbatov R., et al. Origins of tumor-associated macrophages and neutrophils. Proc. Natl. Acad. Sci. USA 2012, 109:2491-2496.
18. Cortez-Retamozo V., Etzrodt M., Newton A., Ryan R., Pucci F., Sio S.W., Kuswanto W., Rauch P.J., Chudnovskiy A., Iwamoto Y., et al. Angiotensin II drives the production of tumor-promoting macrophages. Immunity 2013, 38:296-308.
19. Crandall M., Shapiro M.B., West M.A. Does splenectomy protect against immune-mediated complications in blunt trauma patients?. Mol. Med. 2009, 15:263-267.
20. Cuenca A.G., Delano M.J., Kelly-Scumpia K.M., Moreno C., Scumpia P.O., Laface D.M., Heyworth P.G., Efron P.A., Moldawer L.L. A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma. Mol. Med. 2011, 17:281-292.
21. Delano M.J., Scumpia P.O., Weinstein J.S., Coco D., Nagaraj S., Kelly-Scumpia K.M., O'Malley K.A., Wynn J.L., Antonenko S., Al-Quran S.Z., et al. MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces Tcell suppression and Th2 polarization in sepsis. J.Exp. Med. 2007, 204:1463-1474.
22. DeNardo D.G., Brennan D.J., Rexhepaj E., Ruffell B., Shiao S.L., Madden S.F., Gallagher W.M., Wadhwani N., Keil S.D., Junaid S.A., et al. Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discov 2011, 1:54-67.
23. Dudziak D., Kamphorst A.O., Heidkamp G.F., Buchholz V.R., Trumpfheller C., Yamazaki S., Cheong C., Liu K., Lee H.W., Park C.G., et al. Differential antigen processing by dendritic cell subsets invivo. Science 2007, 315:107-111.
24. Dutta P., Courties G., Wei Y., Leuschner F., Gorbatov R., Robbins C.S., Iwamoto Y., Thompson B., Carlson A.L., Heidt T., et al. Myocardial infarction accelerates atherosclerosis. Nature 2012, 487:325-329.
25. Faunce D.E., Stein-Streilein J. NKT cell-derived RANTES recruits APCs and CD8+ Tcells to the spleen during the generation of regulatory Tcells in tolerance. J.Immunol. 2002, 169:31-38.
26. Fotiadis C., Zografos G., Aronis K., Dousaitou B., Sechas M., Skalkeas G. The effect of various types of splenectomy on the development of B-16 melanoma in mice. Int. J. Surg. Investig. 1999, 1:113-120.
27. Freedman M.H., Saunders E.F. Hematopoiesis in the human spleen. Am. J. Hematol. 1981, 11:271-275.
28. Gabrilovich D.I., Ostrand-Rosenberg S., Bronte V. Coordinated regulation of myeloid cells by tumours. Nat. Rev. Immunol. 2012, 12:253-268.
29. Gardner J.M., Devoss J.J., Friedman R.S., Wong D.J., Tan Y.X., Zhou X., Johannes K.P., Su M.A., Chang H.Y., Krummel M.F., Anderson M.S. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science 2008, 321:843-847.
30. Gardner J.M., Metzger T.C., McMahon E.J., Au-Yeung B.B., Krawisz A.K., Lu W., Price J.D., Johannes K.P., Satpathy A.T., Murphy K.M., et al. Extrathymic Aire-Expressing Cells Are a Distinct Bone Marrow-Derived Population that Induce Functional Inactivation of CD4(+) T Cells. Immunity 2013, 39:560-572.
31. Gatto D., Wood K., Caminschi I., Murphy-Durland D., Schofield P., Christ D., Karupiah G., Brink R. The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells. Nat. Immunol. 2013, 14:446-453.
32. Geissmann F., Manz M.G., Jung S., Sieweke M.H., Merad M., Ley K. Development of monocytes, macrophages, and dendritic cells. Science 2010, 327:656-661.
33. Germano G., Frapolli R., Belgiovine C., Anselmo A., Pesce S., Liguori M., Erba E., Uboldi S., Zucchetti M., Pasqualini F., et al. Role of macrophage targeting in the antitumor activity of trabectedin. Cancer Cell 2013, 23:249-262.
34. Getts D.R., Turley D.M., Smith C.E., Harp C.T., McCarthy D., Feeney E.M., Getts M.T., Martin A.J., Luo X., Terry R.L., et al. Tolerance induced by apoptotic antigen-coupled leukocytes is induced by PD-L1+ and IL-10-producing splenic macrophages and maintained by T regulatory cells. J.Immunol. 2011, 187:2405-2417.
35. Goodman J.W., Hodgson G.S. Evidence for stem cells in the peripheral blood of mice. Blood 1962, 19:702-714.
36. Grainger J.R., Wohlfert E.A., Fuss I.J., Bouladoux N., Askenase M.H., Legrand F., Koo L.Y., Brenchley J.M., Fraser I.D., Belkaid Y. Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection. Nat. Med. 2013, 19:713-721.
37. Griseri T., McKenzie B.S., Schiering C., Powrie F. Dysregulated hematopoietic stem and progenitor cell activity promotes interleukin-23-driven chronic intestinal inflammation. Immunity 2012, 37:1116-1129.
38. Guilliams M., De Kleer I., Henri S., Post S., Vanhoutte L., De Prijck S., Deswarte K., Malissen B., Hammad H., Lambrecht B.N. Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF. J.Exp. Med. 2013, 210:1977-1992.
39. Gunn M.D., Kyuwa S., Tam C., Kakiuchi T., Matsuzawa A., Williams L.T., Nakano H. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J.Exp. Med. 1999, 189:451-460.
40. Hannedouche S., Zhang J., Yi T., Shen W., Nguyen D., Pereira J.P., Guerini D., Baumgarten B.U., Roggo S., Wen B., et al. Oxysterols direct immune cell migration via EBI2. Nature 2011, 475:524-527.
41. Hashimoto D., Chow A., Noizat C., Teo P., Beasley M.B., Leboeuf M., Becker C.D., See P., Price J., Lucas D., et al. Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity 2013, 38:792-804.
42. Haverkamp J.M., Crist S.A., Elzey B.D., Cimen C., Ratliff T.L. Invivo suppressive function of myeloid-derived suppressor cells is limited to the inflammatory site. Eur. J. Immunol. 2011, 41:749-759.
43. Hoeffel G., Wang Y., Greter M., See P., Teo P., Malleret B., Leboeuf M., Low D., Oller G., Almeida F., et al. Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J.Exp. Med. 2012, 209:1167-1181.
44. Hozumi K., Negishi N., Suzuki D., Abe N., Sotomaru Y., Tamaoki N., Mailhos C., Ish-Horowicz D., Habu S., Owen M.J. Delta-like 1 is necessary for the generation of marginal zone B cells but not Tcells invivo. Nat. Immunol. 2004, 5:638-644.
45. Iyoda T., Shimoyama S., Liu K., Omatsu Y., Akiyama Y., Maeda Y., Takahara K., Steinman R.M., Inaba K. The CD8+ dendritic cell subset selectively endocytoses dying cells in culture and invivo. J.Exp. Med. 2002, 195:1289-1302.
46. Jaiswal S., Jamieson C.H., Pang W.W., Park C.Y., Chao M.P., Majeti R., Traver D., van Rooijen N., Weissman I.L. CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell 2009, 138:271-285.
47. Jenkins S.J., Ruckerl D., Cook P.C., Jones L.H., Finkelman F.D., van Rooijen N., MacDonald A.S., Allen J.E. Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation. Science 2011, 332:1284-1288.
48. Kabashima K., Banks T.A., Ansel K.M., Lu T.T., Ware C.F., Cyster J.G. Intrinsic lymphotoxin-beta receptor requirement for homeostasis of lymphoid tissue dendritic cells. Immunity 2005, 22:439-450.
49. Kang S.J., Liang H.E., Reizis B., Locksley R.M. Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells. Immunity 2008, 29:819-833.
50. Klebanoff C.A., Spencer S.P., Torabi-Parizi P., Grainger J.R., Roychoudhuri R., Ji Y., Sukumar M., Muranski P., Scott C.D., Hall J.A., et al. Retinoic acid controls the homeostasis of pre-cDC-derived splenic and intestinal dendritic cells. J.Exp. Med. 2013, 210:1961-1976.
51. Kroemer G., Galluzzi L., Kepp O., Zitvogel L. Immunogenic cell death in cancer therapy. Annu. Rev. Immunol. 2013, 31:51-72.
52. Leuschner F., Dutta P., Gorbatov R., Novobrantseva T.I., Donahoe J.S., Courties G., Lee K.M., Kim J.I., Markmann J.F., Marinelli B., et al. Therapeutic siRNA silencing in inflammatory monocytes in mice. Nat. Biotechnol. 2011, 29:1005-1010.
53. Leuschner F., Rauch P.J., Ueno T., Gorbatov R., Marinelli B., Lee W.W., Dutta P., Wei Y., Robbins C., Iwamoto Y., et al. Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis. J.Exp. Med. 2012, 209:123-137.
54. Lewis K.L., Caton M.L., Bogunovic M., Greter M., Grajkowska L.T., Ng D., Klinakis A., Charo I.F., Jung S., Gommerman J.L., et al. Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine. Immunity 2011, 35:780-791.
55. Lin H.H., Faunce D.E., Stacey M., Terajewicz A., Nakamura T., Zhang-Hoover J., Kerley M., Mucenski M.L., Gordon S., Stein-Streilein J. The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory Tcells in peripheral tolerance. J.Exp. Med. 2005, 201:1615-1625.
56. Lindmark E., Chen Y., Georgoudaki A.M., Dudziak D., Lindh E., Adams W.C., Loré K., Winqvist O., Chambers B.J., Karlsson M.C. AIRE expressing marginal zone dendritic cells balances adaptive immunity and T-follicular helper cell recruitment. J.Autoimmun. 2013, 42:62-70.
57. Liu C., Yang X.V., Wu J., Kuei C., Mani N.S., Zhang L., Yu J., Sutton S.W., Qin N., Banie H., et al. Oxysterols direct B-cell migration through EBI2. Nature 2011, 475:519-523.
58. Lu T.T., Cyster J.G. Integrin-mediated long-term B cell retention in the splenic marginal zone. Science 2002, 297:409-412.
59. Lutterotti A., Yousef S., Sputtek A., Sturner K.H., Stellmann J.P., Breiden P., Reinhardt S., Schulze C., Bester M., Heesen C., et al. Antigen-specific tolerance by autologous myelin peptide-coupled cells: a phase 1 trial in multiple sclerosis. Sci Transl Med. 2013, 5:188.
60. MacNeal W.J. The circulation of blood through the spleen pulp. Arch. Pathol. (Chic) 1929, 7:215-227.
61. Makarenkova V.P., Bansal V., Matta B.M., Perez L.A., Ochoa J.B. CD11b+/Gr-1+ myeloid suppressor cells cause Tcell dysfunction after traumatic stress. J.Immunol. 2006, 176:2085-2094.
62. Marigo I., Bosio E., Solito S., Mesa C., Fernandez A., Dolcetti L., Ugel S., Sonda N., Bicciato S., Falisi E., et al. Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor. Immunity 2010, 32:790-802.
63. Masli S., Turpie B., Hecker K.H., Streilein J.W. Expression of thrombospondin in TGFbeta-treated APCs and its relevance to their immune deviation-promoting properties. J.Immunol. 2002, 168:2264-2273.
64. Massberg S., Schaerli P., Knezevic-Maramica I., Köllnberger M., Tubo N., Moseman E.A., Huff I.V., Junt T., Wagers A.J., Mazo I.B., von Andrian U.H. Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues. Cell 2007, 131:994-1008.
65. Mathis D., Benoist C. Aire. Annu. Rev. Immunol. 2009, 27:287-312.
66. McAlpine H.M., Cobbe S.M. Neuroendocrine changes in acute myocardial infarction. Am. J. Med. 1988, 84(3A):61-66.
67. McGaha T.L., Chen Y., Ravishankar B., van Rooijen N., Karlsson M.C. Marginal zone macrophages suppress innate and adaptive immunity to apoptotic cells in the spleen. Blood 2011, 117:5403-5412.
68. Mebius R.E., Kraal G. Structure and function of the spleen. Nat. Rev. Immunol. 2005, 5:606-616.
69. Mellemkjoer L., Olsen J.H., Linet M.S., Gridley G., McLaughlin J.K. Cancer risk after splenectomy. Cancer 1995, 75:577-583.
70. Merad M., Sathe P., Helft J., Miller J., Mortha A. The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. Annu. Rev. Immunol. 2013, 31:563-604.
71. Mercier F.E., Ragu C., Scadden D.T. The bone marrow at the crossroads of blood and immunity. Nat. Rev. Immunol. 2012, 12:49-60.
72. Metschnikoff E. Der Kampf der Phagocyten gegen Krankeitserreger. Virchows Archiv 1884, 96:177-195.
73. Miller S.D., Hanson D.G. Inhibition of specific immune responses by feeding protein antigens. IV. Evidence for tolerance and specific active suppression of cell-mediated immune responses to ovalbumin. J.Immunol. 1979, 123:2344-2350.
74. Miyake Y., Asano K., Kaise H., Uemura M., Nakayama M., Tanaka M. Critical role of macrophages in the marginal zone in the suppression of immune responses to apoptotic cell-associated antigens. J.Clin. Invest. 2007, 117:2268-2278.
75. Mueller S.N., Germain R.N. Stromal cell contributions to the homeostasis and functionality of the immune system. Nat. Rev. Immunol. 2009, 9:618-629.
76. Muppidi J.R., Arnon T.I., Bronevetsky Y., Veerapen N., Tanaka M., Besra G.S., Cyster J.G. Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone. J.Exp. Med. 2011, 208:1941-1948.
77. Murphy A.J., Akhtari M., Tolani S., Pagler T., Bijl N., Kuo C.L., Wang M., Sanson M., Abramowicz S., Welch C., et al. ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice. J.Clin. Invest. 2011, 121:4138-4149.
78. Nahrendorf M., Swirski F.K., Aikawa E., Stangenberg L., Wurdinger T., Figueiredo J.L., Libby P., Weissleder R., Pittet M.J. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J.Exp. Med. 2007, 204:3037-3047.
79. Ngo V.N., Korner H., Gunn M.D., Schmidt K.N., Riminton D.S., Cooper M.D., Browning J.L., Sedgwick J.D., Cyster J.G. Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and Tcell areas of the spleen. J.Exp. Med. 1999, 189:403-412.
80. Norris B.A., Uebelhoer L.S., Nakaya H.I., Price A.A., Grakoui A., Pulendran B. Chronic but not acute virus infection induces sustained expansion of myeloid suppressor cell numbers that inhibit viral-specific Tcell immunity. Immunity 2013, 38:309-321.
81. O'Keane J.C., Wolf B.C., Neiman R.S. The pathogenesis of splenic extramedullary hematopoiesis in metastatic carcinoma. Cancer 1989, 63:1539-1543.
82. Oakley O.R., Kim H., El-Amouri I., Lin P.C., Cho J., Bani-Ahmad M., Ko C. Periovulatory leukocyte infiltration in the rat ovary. Endocrinology 2010, 151:4551-4559.
83. Ohyagi H., Onai N., Sato T., Yotsumoto S., Liu J., Akiba H., Yagita H., Atarashi K., Honda K., Roers A., et al. Monocyte-derived dendritic cells perform hemophagocytosis to fine-tune excessive immune responses. Immunity 2013, 39:584-598.
84. Pellas T.C., Weiss L. Deep splenic lymphatic vessels in the mouse: a route of splenic exit for recirculating lymphocytes. Am. J. Anat. 1990, 187:347-354.
85. Pillai S., Cariappa A. The follicular versus marginal zone B lymphocyte cell fate decision. Nat. Rev. Immunol. 2009, 9:767-777.
86. Pittet M.J., Weissleder R. Intravital imaging. Cell 2011, 147:983-991.
87. Pylayeva-Gupta Y., Lee K.E., Hajdu C.H., Miller G., Bar-Sagi D. Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia. Cancer Cell 2012, 21:836-847.
88. Qian B.Z., Pollard J.W. Macrophage diversity enhances tumor progression and metastasis. Cell 2010, 141:39-51.
89. Qiu C.H., Miyake Y., Kaise H., Kitamura H., Ohara O., Tanaka M. Novel subset of CD8alpha+ dendritic cells localized in the marginal zone is responsible for tolerance to cell-associated antigens. J.Immunol. 2009, 182:4127-4136.
90. Ram S., Lewis L.A., Rice P.A. Infections of people with complement deficiencies and patients who have undergone splenectomy. Clin. Microbiol. Rev. 2010, 23:740-780.
91. Rauch P.J., Chudnovskiy A., Robbins C.S., Weber G.F., Etzrodt M., Hilgendorf I., Tiglao E., Figueiredo J.L., Iwamoto Y., Theurl I., et al. Innate response activator B cells protect against microbial sepsis. Science 2012, 335:597-601.
92. Ravishankar B., McGaha T.L. O death where is thy sting? Immunologic tolerance to apoptotic self. Cell. Mol. Life Sci. 2013, 70:3571-3589.
93. Ravishankar B., Liu H., Shinde R., Chandler P., Baban B., Tanaka M., Munn D.H., Mellor A.L., Karlsson M.C., McGaha T.L. Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase. Proc. Natl. Acad. Sci. USA 2012, 109:3909-3914.
94. Robbins C.S., Chudnovskiy A., Rauch P.J., Figueiredo J.L., Iwamoto Y., Gorbatov R., Etzrodt M., Weber G.F., Ueno T., van Rooijen N., et al. Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions. Circulation 2012, 125:364-374.
95. Robbins C.S., Hilgendorf I., Weber G.F., Theurl I., Iwamoto Y., Figueiredo J.L., Gorbatov R., Sukhova G.K., Gerhardt L.M., Smyth D., et al. Local proliferation dominates lesional macrophage accumulation in atherosclerosis. Nat. Med. 2013, 19:1166-1172.
96. Robinette C.D., Fraumeni J.F.J. Splenectomy and subsequent mortality in veterans of the 1939-45 war. Lancet 1977, 2:127-129.
97. Sancho D., Joffre O.P., Keller A.M., Rogers N.C., Martínez D., Hernanz-Falcón P., Rosewell I., Reis e Sousa C. Identification of a dendritic cell receptor that couples sensing of necrosis to immunity. Nature 2009, 458:899-903.
98. Schieffer B., Schieffer E., Hilfiker-Kleiner D., Hilfiker A., Kovanen P.T., Kaartinen M., Nussberger J., Harringer W., Drexler H. Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: potential implications for inflammation and plaque instability. Circulation 2000, 101:1372-1378.
99. Schulz C., Gomez Perdiguero E., Chorro L., Szabo-Rogers H., Cagnard N., Kierdorf K., Prinz M., Wu B., Jacobsen S.E., Pollard J.W., et al. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science 2012, 336:86-90.
100. Schwarz R.E., Hiserodt J.C. Effects of splenectomy on the development of tumor-specific immunity. J.Surg. Res. 1990, 48:448-453.
101. Serbina N.V., Pamer E.G. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat. Immunol. 2006, 7:311-317.
102. Serbina N.V., Salazar-Mather T.P., Biron C.A., Kuziel W.A., Pamer E.G. TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity 2003, 19:59-70.
103. Sonoda K.H., Exley M., Snapper S., Balk S.P., Stein-Streilein J. CD1-reactive natural killer Tcells are required for development of systemic tolerance through an immune-privileged site. J.Exp. Med. 1999, 190:1215-1226.
104. Steidl C., Lee T., Shah S.P., Farinha P., Han G., Nayar T., Delaney A., Jones S.J., Iqbal J., Weisenburger D.D., et al. Tumor-associated macrophages and survival in classic Hodgkin's lymphoma. N.Engl. J. Med. 2010, 362:875-885.
105. Streilein J.W. Ocular immune privilege: therapeutic opportunities from an experiment of nature. Nat. Rev. Immunol. 2003, 3:879-889.
106. Streilein J.W., Niederkorn J.Y. Induction of anterior chamber-associated immune deviation requires an intact, functional spleen. J.Exp. Med. 1981, 153:1058-1067.
107. Swirski F.K., Nahrendorf M., Etzrodt M., Wildgruber M., Cortez-Retamozo V., Panizzi P., Figueiredo J.L., Kohler R.H., Chudnovskiy A., Waterman P., et al. Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science 2009, 325:612-616.
108. Tarlinton D., Good-Jacobson K. Diversity among memory B cells: origin, consequences, and utility. Science 2013, 341:1205-1211.
109. Ugel S., Peranzoni E., Desantis G., Chioda M., Walter S., Weinschenk T., Ochando J.C., Cabrelle A., Mandruzzato S., Bronte V. Immune tolerance to tumor antigens occurs in a specialized environment of the spleen. Cell Rep 2012, 2:628-639.
110. van Furth R., Cohn Z.A. The origin and kinetics of mononuclear phagocytes. J.Exp. Med. 1968, 128:415-435.
111. Wang X., Prakash S., Lu M., Tripodi J., Ye F., Najfeld V., Li Y., Schwartz M., Weinberg R., Roda P., et al. Spleens of myelofibrosis patients contain malignant hematopoietic stem cells. J.Clin. Invest. 2012, 122:3888-3899.
112. Weissman I.L., Anderson D.J., Gage F. Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations. Annu. Rev. Cell Dev. Biol. 2001, 17:387-403.
113. Worbs T., Mempel T.R., Bölter J., von Andrian U.H., Förster R. CCR7 ligands stimulate the intranodal motility of T lymphocytes invivo. J.Exp. Med. 2007, 204:489-495.
114. Wright D.E., Wagers A.J., Gulati A.P., Johnson F.L., Weissman I.L. Physiological migration of hematopoietic stem and progenitor cells. Science 2001, 294:1933-1936.
115. Yamazaki S., Dudziak D., Heidkamp G.F., Fiorese C., Bonito A.J., Inaba K., Nussenzweig M.C., Steinman R.M. CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory Tcells. J.Immunol. 2008, 181:6923-6933.
116. Yi T., Cyster J.G. EBI2-mediated bridging channel positioning supports splenic dendritic cell homeostasis and particulate antigen capture. Elife 2013, 2:e00757.
117. Yona S., Kim K.W., Wolf Y., Mildner A., Varol D., Breker M., Strauss-Ayali D., Viukov S., Guilliams M., Misharin A., et al. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity 2013, 38:79-91.
118. Youn J.I., Kumar V., Collazo M., Nefedova Y., Condamine T., Cheng P., Villagra A., Antonia S., McCaffrey J.C., Fishman M., et al. Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer. Nat. Immunol. 2013, 14:211-220.
119. Young M.R., Young M.E., Kim K. Regulation of tumor-induced myelopoiesis and the associated immune suppressor cells in mice bearing metastatic Lewis lung carcinoma by prostaglandin E2. Cancer Res. 1988, 48:6826-6831.
120. Yvan-Charvet L., Pagler T., Gautier E.L., Avagyan S., Siry R.L., Han S., Welch C.L., Wang N., Randolph G.J., Snoeck H.W., Tall A.R. ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation. Science 2010, 328:1689-1693.