Interstitial flow as a guide for lymphangiogenesis

Circulation Research

Volumn 92, Issue 7, 2003, Pages 801-808

  Boardman, Kendrick C ^a   Swartz, Melody A ^a  

^a Northwestern University   (United States)

Author keywords

Interstitial fluid flow; Lymphatic capillary; Lymphatic vessel hyaluronan receptor 1; Matrix metalloproteinases; Vascular endothelial growth factor C

Indexed keywords

COLLAGEN; VASCULOTROPIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CORRELATION ANALYSIS; ENDOTHELIUM CELL; EXPERIMENTAL MODEL; FLUID FLOW; IMPLANT; INTERSTITIAL FLUID; LYMPH FLOW; LYMPH VESSEL; LYMPH VESSEL ENDOTHELIUM; LYMPHATIC SYSTEM; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SKIN; TAIL; TISSUE REGENERATION;

ANIMALS; ANTIGENS, CD31; CELL MOVEMENT; DEXTRANS; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, LYMPHATIC; ENDOTHELIUM, VASCULAR; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOPROTEINS; IMMUNOHISTOCHEMISTRY; LYMPH; LYMPHATIC SYSTEM; LYMPHOGRAPHY; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED BALB C; SKIN; TAIL; VASCULAR ENDOTHELIAL GROWTH FACTOR C; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3;

EID: 0037453703     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000065621.69843.49     Document Type: Article

References (33)

1. Joukov V, Pajusola K, Kaipainen A, Chilov D, Lahtinen I, Kukk E, Saksela O, Kalkkinen N, Alitalo K. A novel vascular endothelial growth factor. VEGF-C. is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J. 1996;15:1751.
2. Lee J, Gray A, Yuan J, Luoh SM, Avraham H, Wood WI. Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt-4. Proc Natl Acad Sci U S A. 1996;93:1988-1992.
3. Jeltsch M, Kaipainen A, Joukov V, Meng X, Lakso M, Rauvala H, Swartz M, Fukumara D, Jain R, Alitalo K. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science. 1997;276:1423-1425.
4. Achen MG, Jeltsch M, Kukk E, Makinen T, Vitali A, Wilks AF, Alitalo K, Stacker SA. Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). Proc Natl Acad Sci U S A. 1998;95:548-553.
5. Kaipainen A, Korhonen J, Mustonen T, Fang GH, Dumont D, Breitman M, Alitalo K. Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc Natl Acad Sci USA. 1995;92:3566-3570.
6. Wigle JT, Oliver G. Prox 1 function is required for the development of the murine lymphatic system. Cell. 1999;98:769-778.
7. Tan Y. Basic fibroblast growth factor-mediated lymphangiogenesis of lymphatic endothelial cells isolated from dog thoracic ducts: effects of heparin. Jpn J Physiol. 1998;48:133-141.
8. Banerji S, Ni J, Wang S, Clasper S, Su J, Tammi R, Jones M, Jackson DG. LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J Cell Biol. 1999;144:789-801.
9. Prevo R, Banerji S, Ferguson DJP, Clasper S, Jackson DG. Mouse LYVE-1 is an endocytic receptor for hyaluronan in lymphatic endothelium. J Biol Chem. 2001;276:19420-19430.
10. Jackson DG. The lymphatics revisited: new perspectives from the hyaluronan receptor LYVE-1. Trends Cardiovasc Med. 2003;13:1-7.
11. Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature. 2000;407:249-257.
12. Bunn HF, Poyton RO. Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev. 1996;76:839-885,
13. Swartz MA. The physiology of the lymphatic system. Adv Drug Deliv Rev. 2001;50:3-20.
14. Swartz MA, Berk DA, Jain RK. Transport in lymphatic capillaries, I: macroscopic measurement using residence time distribution analysis. Am J Physiol. 1996;270:H324-H329.
15. Swartz MA, Kaipainen A, Netti PA, Brekken C, Boucher Y, Grodzinsky AJ, Jain RK. Mechanics of interstitial-lymphatic fluid transport: theoretical foundation and experimental validation. J Biomech. 1999;32:1297-1301.
16. Slavin SA, Van den Abbeele AD, Losken A, Swartz MA, Jain RK. Return of lymphatic function after flap transfer for acute lymphedema. Ann Surg. 1999;229:421-427.
17. Vailhe B, Vittet D, Feige JJ. In vitro models of vasculogenesis and angiogenesis. Lab Invest. 2001;81:439-452.
18. Bell E, Ivarsson B, Merrill C. Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro. Proc Natl Acad Sci U S A. 1979;76:1274-1278.
19. Bollinger A, Jäger K, Sgier F, Seglias J. Fluorescence microlymphangiography. Circulation. 1981;64:1195-1200.
20. Stefanini M, DeMartino C, Zamboni L. Fixation of ejaculated spermatozoa for electron microscopy. Nature. 1967;216:173-174.
21. Oh LYS, Larsen PH, Krekoski CA, Edwards DR, Donovan F, Werb Z, Yong VW. Matrix metalloproteinase-9/gelatinase B is required for process outgrowth by oligodendrocytes. J Neurosci. 1999;19:8464-8475.
22. Valtola R, Salven P, Heikkila P, Taipale J, Joensuu H, Rehn M, Pihlajaniemi T, Weich H, deWaal R, Alitalo K. VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer. Am J Pathol. 1999;154:1381-1390.
23. Paavonen K, Puolakkainen P, Jussila L, Jahkola T, Alitalo K. Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing. Am J Pathol. 2000;156:1499-1504.
24. Partanen TA, Arola J, Saaristo A, Jussila L, Ora A, Miettinen M, Stacker SA, Achen MG, Alitalo K. VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues. FASEB J. 2000;14:2087-2096.
25. Mouta Carreira C, Nasser SM, di Tomaso E, Padera TP, Boucher Y, Tomarev SI, Jain RK. LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis. Cancer Res. 2001;61:8079-8084.
26. Erhard H, Rietveld FJR, Brocker EB, de Waal RMW, Ruiter DJ. Phenotype of normal cutaneous microvasculature. J Invest Dermatol. 1996;106:135-140.
27. Reichert FL. The regeneration of the lymphatics. Arch Surg. 1926;13:871-881.
28. Clark ER, Clark EL. Observation on the new growth of lymphatic vessels as seen in transparent chambers introduced into the rabbit's ear. Am J Anat. 1932;51:43-87.
29. Bellman S, Oden B. Regeneration of surgically divided lymph vessels: an experimental study on the rabbit's ear. Acta Chir Scand. 1958;116:99-117.
30. Gunn MD, Tangemann K, Tam C, Cyster JG, Rosen SD, Williams LT. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. Proc Natl Acad Sci USA. 1998;95:258-263.
31. Lauer-Fields JL, Juska D, Fields GB. Matrix metalloproteinases and collagen catabolism. Biopolymers. 2002;66:19-32.
32. Karkkainen MJ, Saaristo A, Jussila L, Karila KA, Lawrence EC, Pajusola K, Bueler H, Eichmann A, Kauppinen R, Kettunen MI, et al. A model for gene therapy of human hereditary lymphedema. Proc Natl Acad Sci U S A. 2001;98:12677-12682.
33. Makinen T, Jussila L, Veikkola T, Karpanen T, Kettunen MI, Pulkkanen KJ, Kauppinen R, Jackson DG, Kubo H, Nishikawa S, Yla-Herttuala S, Alitalo K. Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nat Med. 2001;7:199-205.