메뉴 건너뛰기




Volumn 189, Issue 5, 2012, Pages 2181-2190

Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; IMMUNOGLOBULIN M; INTERLEUKIN 10; INTERLEUKIN 4; OVALBUMIN; VASCULOTROPIN RECEPTOR 3;

EID: 84865424661     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1103545     Document Type: Article
Times cited : (107)

References (63)
  • 1
    • 0015518318 scopus 로고
    • Immunologic tolerance: Role of the regional lymph node
    • Friedlaender, M. H., and H. Baer. 1972. Immunologic tolerance: role of the regional lymph node. Science 176: 312-314.
    • (1972) Science , vol.176 , pp. 312-314
    • Friedlaender, M.H.1    Baer, H.2
  • 2
    • 0015641605 scopus 로고
    • The role of the inflammatory response of skin and lymph nodes in the induction of sensitization to simple chemicals
    • Friedlaender, M. H., F. V. Chisari, and H. Baer. 1973. The role of the inflammatory response of skin and lymph nodes in the induction of sensitization to simple chemicals. J. Immunol. 111: 164-170.
    • (1973) J. Immunol. , vol.111 , pp. 164-170
    • Friedlaender, M.H.1    Chisari, F.V.2    Baer, H.3
  • 3
    • 33750808166 scopus 로고    scopus 로고
    • Induction of tolerance to innocuous inhaled antigen relies on a CCR7-dependent dendritic cell-mediated antigen transport to the bronchial lymph node
    • Hintzen, G., L. Ohl, M. L. del Rio, J. I. Rodriguez-Barbosa, O. Pabst, J. R. Kocks, J. Krege, S. Hardtke, and R. Förster. 2006. Induction of tolerance to innocuous inhaled antigen relies on a CCR7-dependent dendritic cell-mediated antigen transport to the bronchial lymph node. J. Immunol. 177: 7346-7354.
    • (2006) J. Immunol. , vol.177 , pp. 7346-7354
    • Hintzen, G.1    Ohl, L.2    Del Rio, M.L.3    Rodriguez-Barbosa, J.I.4    Pabst, O.5    Kocks, J.R.6    Krege, J.7    Hardtke, S.8    Förster, R.9
  • 4
    • 65349115397 scopus 로고    scopus 로고
    • Peripheral tolerance induction by lymph node stroma
    • S. P. Schoenberger, P. D. Katsikis, and B. Pulendran, eds. Springer, New York
    • Reynoso, E. D., J. W. Lee, and S. J. Turley. 2009. Peripheral tolerance induction by lymph node stroma. In Crossroads between Innate and Adaptive Immunity II. S. P. Schoenberger, P. D. Katsikis, and B. Pulendran, eds. Springer, New York, p. 113-127.
    • (2009) Crossroads between Innate and Adaptive Immunity II , pp. 113-127
    • Reynoso, E.D.1    Lee, J.W.2    Turley, S.J.3
  • 5
    • 0036314122 scopus 로고    scopus 로고
    • Reactivity to bacterial, fungal, and parasite antigens in patients with lymphedema and elephantiasis
    • Baird, J. B., J. L. Charles, T. G. Streit, J. M. Roberts, D. G. Addiss, and P. J. Lammie. 2002. Reactivity to bacterial, fungal, and parasite antigens in patients with lymphedema and elephantiasis. Am. J. Trop. Med. Hyg. 66: 163-169.
    • (2002) Am. J. Trop. Med. Hyg. , vol.66 , pp. 163-169
    • Baird, J.B.1    Charles, J.L.2    Streit, T.G.3    Roberts, J.M.4    Addiss, D.G.5    Lammie, P.J.6
  • 6
    • 79958817911 scopus 로고    scopus 로고
    • Role of the lymphatic system in the pathogenesis of Crohn's disease
    • von der Weid, P. Y., S. Rehal, and J. G. P. Ferraz. 2011. Role of the lymphatic system in the pathogenesis of Crohn's disease. Curr. Opin. Gastroenterol. 27: 335-341.
    • (2011) Curr. Opin. Gastroenterol. , vol.27 , pp. 335-341
    • Von Der Weid, P.Y.1    Rehal, S.2    Ferraz, J.G.P.3
  • 8
    • 36148936760 scopus 로고    scopus 로고
    • VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes
    • Halin, C., N. E. Tobler, B. Vigl, L. F. Brown, and M. Detmar. 2007. VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes. Blood 110: 3158-3167.
    • (2007) Blood , vol.110 , pp. 3158-3167
    • Halin, C.1    Tobler, N.E.2    Vigl, B.3    Brown, L.F.4    Detmar, M.5
  • 9
    • 79959657080 scopus 로고    scopus 로고
    • Targeting lymphangiogenesis after islet transplantation prolongs islet allograft survival
    • Yin, N., N. Zhang, J. N. Xu, Q. X. Shi, Y. Z. Ding, and J. S. Bromberg. 2011. Targeting lymphangiogenesis after islet transplantation prolongs islet allograft survival. Transplantation 92: 25-30.
    • (2011) Transplantation , vol.92 , pp. 25-30
    • Yin, N.1    Zhang, N.2    Xu, J.N.3    Shi, Q.X.4    Ding, Y.Z.5    Bromberg, J.S.6
  • 11
    • 73649130264 scopus 로고    scopus 로고
    • Crucial role of corneal lymphangiogenesis for allograft rejection in alkali-burned cornea bed
    • Ling, S., C. Qi, W. Li, J. Xu, and W. Kuang. 2009. Crucial role of corneal lymphangiogenesis for allograft rejection in alkali-burned cornea bed. Clin. Experiment. Ophthalmol. 37: 874-883.
    • (2009) Clin. Experiment. Ophthalmol. , vol.37 , pp. 874-883
    • Ling, S.1    Qi, C.2    Li, W.3    Xu, J.4    Kuang, W.5
  • 12
    • 76249095735 scopus 로고    scopus 로고
    • Cutting edge: Lymphatic vessels, not blood vessels, primarily mediate immune rejections after transplantation
    • Dietrich, T., F. Bock, D. Yuen, D. Hos, B. O. Bachmann, G. Zahn, S. Wiegand, L. Chen, and C. Cursiefen. 2010. Cutting edge: lymphatic vessels, not blood vessels, primarily mediate immune rejections after transplantation. J. Immunol. 184: 535-539.
    • (2010) J. Immunol. , vol.184 , pp. 535-539
    • Dietrich, T.1    Bock, F.2    Yuen, D.3    Hos, D.4    Bachmann, B.O.5    Zahn, G.6    Wiegand, S.7    Chen, L.8    Cursiefen, C.9
  • 14
    • 36649033639 scopus 로고    scopus 로고
    • Lymphatic neoangiogenesis in renal transplants: A driving force of chronic rejection?
    • Kerjaschki, D. 2006. Lymphatic neoangiogenesis in renal transplants: a driving force of chronic rejection? J. Nephrol. 19: 403-406.
    • (2006) J. Nephrol. , vol.19 , pp. 403-406
    • Kerjaschki, D.1
  • 17
    • 33947494918 scopus 로고    scopus 로고
    • Tumor-induced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis
    • Harrell, M. I., B. M. Iritani, and A. Ruddell. 2007. Tumor-induced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis. Am. J. Pathol. 170: 774-786.
    • (2007) Am. J. Pathol. , vol.170 , pp. 774-786
    • Harrell, M.I.1    Iritani, B.M.2    Ruddell, A.3
  • 18
    • 84857573201 scopus 로고    scopus 로고
    • Sentinel lymph node lymphangiogenesis and increased lymph flow in murine tumor metastasis
    • Ruddell, A., M. I. Harrell, and M. Furuya. 2009. Sentinel lymph node lymphangiogenesis and increased lymph flow in murine tumor metastasis. Clin. Exp. Metastasis 26: 883-884.
    • (2009) Clin. Exp. Metastasis , vol.26 , pp. 883-884
    • Ruddell, A.1    Harrell, M.I.2    Furuya, M.3
  • 20
    • 84857556564 scopus 로고    scopus 로고
    • Lymphatic and interstitial flow in the tumour microenvironment: Linking mechanobiology with immunity
    • Swartz, M. A., and A. W. Lund. 2012. Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity. Nat. Rev. Cancer 12: 210-219.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 210-219
    • Swartz, M.A.1    Lund, A.W.2
  • 21
    • 23444451916 scopus 로고    scopus 로고
    • Dendritic-cell trafficking to lymph nodes through lymphatic vessels
    • Randolph, G. J., V. Angeli, and M. A. Swartz. 2005. Dendritic-cell trafficking to lymph nodes through lymphatic vessels. Nat. Rev. Immunol. 5: 617-628.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 617-628
    • Randolph, G.J.1    Angeli, V.2    Swartz, M.A.3
  • 24
    • 0042696999 scopus 로고    scopus 로고
    • Antigen presentation to naive CD4 T cells in the lymph node
    • Itano, A. A., and M. K. Jenkins. 2003. Antigen presentation to naive CD4 T cells in the lymph node. Nat. Immunol. 4: 733-739.
    • (2003) Nat. Immunol. , vol.4 , pp. 733-739
    • Itano, A.A.1    Jenkins, M.K.2
  • 25
    • 42649086026 scopus 로고    scopus 로고
    • CCR7 and its ligands: Balancing immunity and tolerance
    • Förster, R., A. C. Davalos-Misslitz, and A. Rot. 2008. CCR7 and its ligands: balancing immunity and tolerance. Nat. Rev. Immunol. 8: 362-371.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 362-371
    • Förster, R.1    Davalos-Misslitz, A.C.2    Rot, A.3
  • 26
    • 70249085585 scopus 로고    scopus 로고
    • Stromal cell contributions to the homeostasis and functionality of the immune system
    • Mueller, S. N., and R. N. Germain. 2009. Stromal cell contributions to the homeostasis and functionality of the immune system. Nat. Rev. Immunol. 9: 618-629.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 618-629
    • Mueller, S.N.1    Germain, R.N.2
  • 27
    • 33645106845 scopus 로고    scopus 로고
    • Lymphoid organ development: From ontogeny to neogenesis
    • Drayton, D. L., S. Liao, R. H. Mounzer, and N. H. Ruddle. 2006. Lymphoid organ development: from ontogeny to neogenesis. Nat. Immunol. 7: 344-353.
    • (2006) Nat. Immunol. , vol.7 , pp. 344-353
    • Drayton, D.L.1    Liao, S.2    Mounzer, R.H.3    Ruddle, N.H.4
  • 28
    • 0035862332 scopus 로고    scopus 로고
    • Mice lacking expression of the chemokines CCL21-ser and CCL19 (plt mice) demonstrate delayed but enhanced T cell immune responses
    • Mori, S., H. Nakano, K. Aritomi, C. R. Wang, M. D. Gunn, and T. Kakiuchi. 2001. Mice lacking expression of the chemokines CCL21-ser and CCL19 (plt mice) demonstrate delayed but enhanced T cell immune responses. J. Exp. Med. 193: 207-218.
    • (2001) J. Exp. Med. , vol.193 , pp. 207-218
    • Mori, S.1    Nakano, H.2    Aritomi, K.3    Wang, C.R.4    Gunn, M.D.5    Kakiuchi, T.6
  • 30
    • 70350131707 scopus 로고    scopus 로고
    • CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens
    • Nitta, T., S. Nitta, Y. Lei, M. Lipp, and Y. Takahama. 2009. CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens. Proc. Natl. Acad. Sci. USA 106: 17129-17133.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 17129-17133
    • Nitta, T.1    Nitta, S.2    Lei, Y.3    Lipp, M.4    Takahama, Y.5
  • 32
    • 34250630932 scopus 로고    scopus 로고
    • Distinctive role of CCR7 in migration and functional activity of naive- and effector/memory-like Treg subsets
    • Menning, A., U. E. Höpken, K. Siegmund, M. Lipp, A. Hamann, and J. Huehn. 2007. Distinctive role of CCR7 in migration and functional activity of naive- and effector/memory-like Treg subsets. Eur. J. Immunol. 37: 1575-1583.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 1575-1583
    • Menning, A.1    Höpken, U.E.2    Siegmund, K.3    Lipp, M.4    Hamann, A.5    Huehn, J.6
  • 35
    • 77951069509 scopus 로고    scopus 로고
    • Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
    • Cohen, J. N., C. J. Guidi, E. F. Tewalt, H. Qiao, S. J. Rouhani, A. Ruddell, A. G. Farr, K. S. Tung, and V. H. Engelhard. 2010. Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation. J. Exp. Med. 207: 681-688.
    • (2010) J. Exp. Med. , vol.207 , pp. 681-688
    • Cohen, J.N.1    Guidi, C.J.2    Tewalt, E.F.3    Qiao, H.4    Rouhani, S.J.5    Ruddell, A.6    Farr, A.G.7    Tung, K.S.8    Engelhard, V.H.9
  • 37
    • 77749291801 scopus 로고    scopus 로고
    • Dermal collagen and lipid deposition correlate with tissue swelling and hydraulic conductivity in murine primary lymphedema
    • Rutkowski, J. M., C. E. Markhus, C. C. Gyenge, K. Alitalo, H. Wiig, and M. A. Swartz. 2010. Dermal collagen and lipid deposition correlate with tissue swelling and hydraulic conductivity in murine primary lymphedema. Am. J. Pathol. 176: 1122-1129.
    • (2010) Am. J. Pathol. , vol.176 , pp. 1122-1129
    • Rutkowski, J.M.1    Markhus, C.E.2    Gyenge, C.C.3    Alitalo, K.4    Wiig, H.5    Swartz, M.A.6
  • 38
    • 0032836105 scopus 로고    scopus 로고
    • Mechanics of interstitial-lymphatic fluid transport: Theoretical foundation and experimental validation
    • Swartz, M. A., A. Kaipainen, P. A. Netti, C. Brekken, Y. Boucher, A. J. Grodzinsky, and R. K. Jain. 1999. Mechanics of interstitial-lymphatic fluid transport: theoretical foundation and experimental validation. J. Biomech. 32: 1297-1307.
    • (1999) J. Biomech. , vol.32 , pp. 1297-1307
    • Swartz, M.A.1    Kaipainen, A.2    Netti, P.A.3    Brekken, C.4    Boucher, Y.5    Grodzinsky, A.J.6    Jain, R.K.7
  • 40
    • 0030051265 scopus 로고    scopus 로고
    • Transport in lymphatic capillaries. I. Macroscopic measurements using residence time distribution theory
    • Swartz, M. A., D. A. Berk, and R. K. Jain. 1996. Transport in lymphatic capillaries. I. Macroscopic measurements using residence time distribution theory. Am. J. Physiol. 270: H324-H329.
    • (1996) Am. J. Physiol. , vol.270
    • Swartz, M.A.1    Berk, D.A.2    Jain, R.K.3
  • 41
    • 33845455093 scopus 로고    scopus 로고
    • Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes
    • Bajénoff, M., J. G. Egen, L. Y. Koo, J. P. Laugier, F. Brau, N. Glaichenhaus, and R. N. Germain. 2006. Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. Immunity 25: 989-1001.
    • (2006) Immunity , vol.25 , pp. 989-1001
    • Bajénoff, M.1    Egen, J.G.2    Koo, L.Y.3    Laugier, J.P.4    Brau, F.5    Glaichenhaus, N.6    Germain, R.N.7
  • 44
    • 0034544489 scopus 로고    scopus 로고
    • Quantitative genetic variation in CD19 expression correlates with autoimmunity
    • Sato, S., M. Hasegawa, M. Fujimoto, T. F. Tedder, and K. Takehara. 2000. Quantitative genetic variation in CD19 expression correlates with autoimmunity. J. Immunol. 165: 6635-6643.
    • (2000) J. Immunol. , vol.165 , pp. 6635-6643
    • Sato, S.1    Hasegawa, M.2    Fujimoto, M.3    Tedder, T.F.4    Takehara, K.5
  • 48
    • 77950300654 scopus 로고    scopus 로고
    • B-cells need a proper house, whereas T-cells are happy in a cave: The dependence of lymphocytes on secondary lymphoid tissues during evolution
    • Hofmann, J., M. Greter, L. Du Pasquier, and B. Becher. 2010. B-cells need a proper house, whereas T-cells are happy in a cave: the dependence of lymphocytes on secondary lymphoid tissues during evolution. Trends Immunol. 31: 144-153.
    • (2010) Trends Immunol. , vol.31 , pp. 144-153
    • Hofmann, J.1    Greter, M.2    Du Pasquier, L.3    Becher, B.4
  • 49
    • 0030070295 scopus 로고    scopus 로고
    • Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis
    • Schröder, A. E., A. Greiner, C. Seyfert, and C. Berek. 1996. Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis. Proc. Natl. Acad. Sci. USA 93: 221-225.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 221-225
    • Schröder, A.E.1    Greiner, A.2    Seyfert, C.3    Berek, C.4
  • 50
    • 0032169223 scopus 로고    scopus 로고
    • Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease: The salivary glands of patients with Sjögren's syndrome
    • Stott, D. I., F. Hiepe, M. Hummel, G. Steinhauser, and C. Berek. 1998. Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease: the salivary glands of patients with Sjögren's syndrome. J. Clin. Invest. 102: 938-946.
    • (1998) J. Clin. Invest. , vol.102 , pp. 938-946
    • Stott, D.I.1    Hiepe, F.2    Hummel, M.3    Steinhauser, G.4    Berek, C.5
  • 54
    • 66249140545 scopus 로고    scopus 로고
    • Neo-lymphoid aggregates in the adult liver can initiate potent cell-mediated immunity
    • Greter, M., J. Hofmann, and B. Becher. 2009. Neo-lymphoid aggregates in the adult liver can initiate potent cell-mediated immunity. PLoS Biol. 7: e1000109.
    • (2009) PLoS Biol. , vol.7 , pp. 1000109
    • Greter, M.1    Hofmann, J.2    Becher, B.3
  • 55
    • 4043049430 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity
    • Chen, L., P. Hamrah, C. Cursiefen, Q. Zhang, B. Pytowski, J. W. Streilein, and M. R. Dana. 2004. Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity. Nat. Med. 10: 813-815.
    • (2004) Nat. Med. , vol.10 , pp. 813-815
    • Chen, L.1    Hamrah, P.2    Cursiefen, C.3    Zhang, Q.4    Pytowski, B.5    Streilein, J.W.6    Dana, M.R.7
  • 56
    • 0037631737 scopus 로고    scopus 로고
    • Novel expression of vascular endothelial growth factor receptor (VEGFR)-3 and VEGF-C on corneal dendritic cells
    • Hamrah, P., L. Chen, Q. Zhang, and M. R. Dana. 2003. Novel expression of vascular endothelial growth factor receptor (VEGFR)-3 and VEGF-C on corneal dendritic cells. Am. J. Pathol. 163: 57-68.
    • (2003) Am. J. Pathol. , vol.163 , pp. 57-68
    • Hamrah, P.1    Chen, L.2    Zhang, Q.3    Dana, M.R.4
  • 59
    • 0026014880 scopus 로고
    • The influence of afferent lymphatic vessel interruption on vascular addressin expression
    • Mebius, R. E., P. R. Streeter, J. Brevé, A. M. Duijvestijn, and G. Kraal. 1991. The influence of afferent lymphatic vessel interruption on vascular addressin expression. J. Cell Biol. 115: 85-95.
    • (1991) J. Cell Biol. , vol.115 , pp. 85-95
    • Mebius, R.E.1    Streeter, P.R.2    Brevé, J.3    Duijvestijn, A.M.4    Kraal, G.5
  • 60
    • 70449713917 scopus 로고    scopus 로고
    • Fluid flow regulates stromal cell organization and CCL21 expression in a tissue-engineered lymph node microenvironment
    • Tomei, A. A., S. Siegert, M. R. Britschgi, S. A. Luther, and M. A. Swartz. 2009. Fluid flow regulates stromal cell organization and CCL21 expression in a tissue-engineered lymph node microenvironment. J. Immunol. 183: 4273-4283.
    • (2009) J. Immunol. , vol.183 , pp. 4273-4283
    • Tomei, A.A.1    Siegert, S.2    Britschgi, M.R.3    Luther, S.A.4    Swartz, M.A.5
  • 61
    • 35348861537 scopus 로고    scopus 로고
    • CXCR5- and CCR7-dependent lymphoid neogenesis in a murine model of chronic antigen-induced arthritis
    • Wengner, A. M., U. E. Höpken, P. K. Petrow, S. Hartmann, U. Schurigt, R. Bräuer, and M. Lipp. 2007. CXCR5- and CCR7-dependent lymphoid neogenesis in a murine model of chronic antigen-induced arthritis. Arthritis Rheum. 56: 3271-3283.
    • (2007) Arthritis Rheum. , vol.56 , pp. 3271-3283
    • Wengner, A.M.1    Höpken, U.E.2    Petrow, P.K.3    Hartmann, S.4    Schurigt, U.5    Bräuer, R.6    Lipp, M.7
  • 63
    • 0037133611 scopus 로고    scopus 로고
    • Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-b production by fibroblasts
    • Kodera, T., T. L. McGaha, R. Phelps, W. E. Paul, and C. A. Bona. 2002. Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-b production by fibroblasts. Proc. Natl. Acad. Sci. USA 99: 3800-3805.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 3800-3805
    • Kodera, T.1    McGaha, T.L.2    Phelps, R.3    Paul, W.E.4    Bona, C.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.