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Volumn 16, Issue 4, 2015, Pages 386-396

The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; PLVAP PROTEIN; PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; CAV1 PROTEIN, MOUSE; CAVEOLIN 1; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; PLVAP PROTEIN, MOUSE;

EID: 84925396037     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3101     Document Type: Article
Times cited : (150)

References (49)
  • 1
    • 84867900263 scopus 로고    scopus 로고
    • HEVs, lymphatics and homeostatic immune cell trafficking in lymph nodes
    • Girard, J.P., Moussion, C. & Forster, R. HEVs, lymphatics and homeostatic immune cell trafficking in lymph nodes. Nat. Rev. Immunol. 12, 762-773 (2012).
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 762-773
    • Girard, J.P.1    Moussion, C.2    Forster, R.3
  • 2
    • 84876910443 scopus 로고    scopus 로고
    • The integration of T cell migration, differentiation and function
    • Masopust, D. & Schenkel, J.M. The integration of T cell migration, differentiation and function. Nat. Rev. Immunol. 13, 309-320 (2013).
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 309-320
    • Masopust, D.1    Schenkel, J.M.2
  • 3
    • 84862976472 scopus 로고    scopus 로고
    • A decade of imaging cellular motility and interaction dynamics in the immune system
    • Germain, R.N., Robey, E.A. & Cahalan, M.D. A decade of imaging cellular motility and interaction dynamics in the immune system. Science 336, 1676-1681 (2012).
    • (2012) Science , vol.336 , pp. 1676-1681
    • Germain, R.N.1    Robey, E.A.2    Cahalan, M.D.3
  • 4
    • 77951597881 scopus 로고    scopus 로고
    • Breaching multiple barriers: Leukocyte motility through venular walls and the interstitium
    • Nourshargh, S., Hordijk, P.L. & Sixt, M. Breaching multiple barriers: leukocyte motility through venular walls and the interstitium. Nat. Rev. Mol. Cell Biol. 11, 366-378 (2011).
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 366-378
    • Nourshargh, S.1    Hordijk, P.L.2    Sixt, M.3
  • 5
    • 38949135155 scopus 로고    scopus 로고
    • The microanatomy of T-cell responses
    • Lämmermann, T. & Sixt, M. The microanatomy of T-cell responses. Immunol. Rev. 221, 26-43 (2008).
    • (2008) Immunol. Rev. , vol.221 , pp. 26-43
    • Lämmermann, T.1    Sixt, M.2
  • 6
    • 0034693949 scopus 로고    scopus 로고
    • Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex
    • Gretz, J.E., Norbury, C.C., Anderson, A.O., Proudfoot, A.E.I. & Shaw, S. Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex. J. Exp. Med. 192, 1425-1440 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 1425-1440
    • Gretz, J.E.1    Norbury, C.C.2    Anderson, A.O.3    Proudfoot, A.E.I.4    Shaw, S.5
  • 7
    • 12444297666 scopus 로고    scopus 로고
    • The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node
    • Sixt, M. et al. The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node. Immunity 22, 19-29 (2005).
    • (2005) Immunity , vol.22 , pp. 19-29
    • Sixt, M.1
  • 8
    • 73949145423 scopus 로고    scopus 로고
    • B-cell follicle development remodels the conduit system and allows soluble antigen delivery to follicular dendritic cells
    • Bajénoff, M. & Germain, R.N. B-cell follicle development remodels the conduit system and allows soluble antigen delivery to follicular dendritic cells. Blood 114, 4989-4997 (2009).
    • (2009) Blood , vol.114 , pp. 4989-4997
    • Bajénoff, M.1    Germain, R.N.2
  • 9
    • 60149086845 scopus 로고    scopus 로고
    • Conduits mediate transport of low-molecular-weight antigen to lymph node follicles
    • Roozendaal, R. et al. Conduits mediate transport of low-molecular-weight antigen to lymph node follicles. Immunity 30, 264-276 (2009).
    • (2009) Immunity , vol.30 , pp. 264-276
    • Roozendaal, R.1
  • 10
    • 0035158575 scopus 로고    scopus 로고
    • Inflammatory chemokine transport and presentation in HEV: A remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues
    • Palframan, R.T. et al. Inflammatory chemokine transport and presentation in HEV: a remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues. J. Exp. Med. 194, 1361-1373 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 1361-1373
    • Palframan, R.T.1
  • 11
    • 84878178323 scopus 로고    scopus 로고
    • Cochlin produced by follicular dendritic cells promotes antibacterial innate immunity
    • Py, B.F. et al. Cochlin produced by follicular dendritic cells promotes antibacterial innate immunity. Immunity 38, 1063-1072 (2013).
    • (2013) Immunity , vol.38 , pp. 1063-1072
    • Py, B.F.1
  • 12
    • 0037769037 scopus 로고    scopus 로고
    • Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity
    • Itano, A.A. et al. Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. Immunity 19, 47-57 (2003).
    • (2003) Immunity , vol.19 , pp. 47-57
    • Itano, A.A.1
  • 13
    • 80052025244 scopus 로고    scopus 로고
    • Afferent lymph-derived T cells and DCs use different chemokine receptor CCR7-dependent routes for entry into the lymph node and intranodal migration
    • Braun, A. et al. Afferent lymph-derived T cells and DCs use different chemokine receptor CCR7-dependent routes for entry into the lymph node and intranodal migration. Nat. Immunol. 12, 879-887 (2011).
    • (2011) Nat. Immunol. , vol.12 , pp. 879-887
    • Braun, A.1
  • 14
    • 84902662442 scopus 로고    scopus 로고
    • The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes
    • Ulvmar, M.H. et al. The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes. Nat. Immunol. 15, 623-630 (2014).
    • (2014) Nat. Immunol. , vol.15 , pp. 623-630
    • Ulvmar, M.H.1
  • 15
    • 0028967989 scopus 로고
    • Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood brain barrier
    • Hallmann, R., Mayer, D.N., Berg, E.L., Broermann, R. & Butcher, E.C. Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood brain barrier. Dev. Dyn. 202, 325-332 (1995).
    • (1995) Dev. Dyn. , vol.202 , pp. 325-332
    • Hallmann, R.1    Mayer, D.N.2    Berg, E.L.3    Broermann, R.4    Butcher, E.C.5
  • 16
    • 34548155656 scopus 로고    scopus 로고
    • Endothelial stomatal and fenestral diaphragms in normal vessels and angiogenesis
    • Stan, R.V. Endothelial stomatal and fenestral diaphragms in normal vessels and angiogenesis. J. Cell. Mol. Med. 11, 621-643 (2007).
    • (2007) J. Cell. Mol. Med. , vol.11 , pp. 621-643
    • Stan, R.V.1
  • 17
    • 0021986961 scopus 로고
    • Monoclonal antibody PAL-E specific for endothelium
    • Schlingemann, R.O. et al. Monoclonal antibody PAL-E specific for endothelium. Lab. Invest. 52, 71-76 (1985).
    • (1985) Lab. Invest. , vol.52 , pp. 71-76
    • Schlingemann, R.O.1
  • 18
    • 33846798106 scopus 로고    scopus 로고
    • Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms
    • Aird, W.C. Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. Circ. Res. 100, 158-173 (2007).
    • (2007) Circ. Res. , vol.100 , pp. 158-173
    • Aird, W.C.1
  • 19
    • 44449138380 scopus 로고    scopus 로고
    • Markers for microscopic imaging of lymphangiogenesis and angiogenesis
    • Baluk, P. & McDonald, D.M. Markers for microscopic imaging of lymphangiogenesis and angiogenesis. Ann. NY Acad. Sci. 1131, 1-12 (2008).
    • (2008) Ann. NY Acad. Sci. , vol.1131 , pp. 1-12
    • Baluk, P.1    McDonald, D.M.2
  • 20
    • 33750937238 scopus 로고    scopus 로고
    • An in vitro assay reveals a role for the diaphragm protein PV-1 in endothelial fenestra morphogenesis
    • Ioannidou, S. et al. An in vitro assay reveals a role for the diaphragm protein PV-1 in endothelial fenestra morphogenesis. Proc. Natl. Acad. Sci. USA 103, 16770-16775 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16770-16775
    • Ioannidou, S.1
  • 21
    • 84870798143 scopus 로고    scopus 로고
    • The diaphragms of fenestrated endothelia: Gatekeepers of vascular permeability and blood composition
    • Stan, R.V. et al. The diaphragms of fenestrated endothelia: gatekeepers of vascular permeability and blood composition. Dev. Cell 23, 1203-1218 (2012).
    • (2012) Dev. Cell , vol.23 , pp. 1203-1218
    • Stan, R.V.1
  • 22
    • 84868115836 scopus 로고    scopus 로고
    • Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient mice
    • Herrnberger, L. et al. Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient mice. Histochem. Cell Biol. 138, 709-724 (2012).
    • (2012) Histochem. Cell Biol. , vol.138 , pp. 709-724
    • Herrnberger, L.1
  • 23
    • 0019957076 scopus 로고
    • Overall architecture and pattern of lymph flow in the rat lymph node
    • Sainte-Marie, G., Peng, F.S. & Belisle, C. Overall architecture and pattern of lymph flow in the rat lymph node. Am. J. Anat. 164, 275-309 (1982).
    • (1982) Am. J. Anat. , vol.164 , pp. 275-309
    • Sainte-Marie, G.1    Peng, F.S.2    Belisle, C.3
  • 24
    • 0018836978 scopus 로고
    • The structure of the sinus wall of the lymph node relative to its endocytic properties and transmural cell passage
    • Farr, A.G., Cho, Y. & De Bruyn, P.P. The structure of the sinus wall of the lymph node relative to its endocytic properties and transmural cell passage. Am. J. Anat. 157, 265-284 (1980).
    • (1980) Am. J. Anat. , vol.157 , pp. 265-284
    • Farr, A.G.1    Cho, Y.2    De Bruyn, P.P.3
  • 25
    • 0022501322 scopus 로고
    • Reticular fibroblasts in peripheral lymphoid organs identified by a monoclonal antibody
    • Van Vliet, E., Melis, M., Foidart, J.M. & Van Ewijk, W. Reticular fibroblasts in peripheral lymphoid organs identified by a monoclonal antibody. J. Histochem. Cytochem. 34, 883-890 (1986).
    • (1986) J. Histochem. Cytochem. , vol.34 , pp. 883-890
    • Van Vliet, E.1    Melis, M.2    Foidart, J.M.3    Van Ewijk, W.4
  • 26
    • 3342972122 scopus 로고    scopus 로고
    • PV1 is a key structural component for the formation of the stomatal and fenestral diaphragms
    • Stan, R.V., Tkachenko, E. & Niesman, I.R. PV1 is a key structural component for the formation of the stomatal and fenestral diaphragms. Mol. Biol. Cell 15, 3615-3630 (2004).
    • (2004) Mol. Biol. Cell , vol.15 , pp. 3615-3630
    • Stan, R.V.1    Tkachenko, E.2    Niesman, I.R.3
  • 27
    • 84901981250 scopus 로고    scopus 로고
    • News from the caves: Update on the structure and function of caveolae
    • Shvets, E., Ludwig, A. & Nichols, B.J. News from the caves: update on the structure and function of caveolae. Curr. Opin. Cell Biol. 29, 99-106 (2014).
    • (2014) Curr. Opin. Cell Biol. , vol.29 , pp. 99-106
    • Shvets, E.1    Ludwig, A.2    Nichols, B.J.3
  • 28
    • 0035851197 scopus 로고    scopus 로고
    • Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities
    • Razani, B. et al. Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. J. Biol. Chem. 276, 38121-38138 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 38121-38138
    • Razani, B.1
  • 29
    • 84863266360 scopus 로고    scopus 로고
    • Caveolae, fenestrae and transendothelial channels retain PV1 on the surface of endothelial cells
    • Tkachenko, E. et al. Caveolae, fenestrae and transendothelial channels retain PV1 on the surface of endothelial cells. PLoS ONE 7, e32655 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e32655
    • Tkachenko, E.1
  • 30
    • 35948935059 scopus 로고    scopus 로고
    • Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells
    • Junt, T. et al. Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature 450, 110-114 (2007).
    • (2007) Nature , vol.450 , pp. 110-114
    • Junt, T.1
  • 31
    • 34548044827 scopus 로고    scopus 로고
    • Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells
    • Phan, T.G., Grigorova, I., Okada, T. & Cyster, J.G. Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells. Nat. Immunol. 8, 992-1000 (2007).
    • (2007) Nat. Immunol. , vol.8 , pp. 992-1000
    • Phan, T.G.1    Grigorova, I.2    Okada, T.3    Cyster, J.G.4
  • 32
    • 84874207942 scopus 로고    scopus 로고
    • Marginal reticular cells: A stromal subset directly descended from the lymphoid tissue organizer
    • Katakai, T. Marginal reticular cells: a stromal subset directly descended from the lymphoid tissue organizer. Front. Immunol. 3, 200 (2012).
    • (2012) Front. Immunol. , vol.3 , pp. 200
    • Katakai, T.1
  • 33
    • 24944569742 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues
    • Debes, G.F. et al. Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues. Nat. Immunol. 6, 889-894 (2005).
    • (2005) Nat. Immunol. , vol.6 , pp. 889-894
    • Debes, G.F.1
  • 34
    • 37349069359 scopus 로고    scopus 로고
    • The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics
    • Ledgerwood, L.G. et al. The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics. Nat. Immunol. 9, 42-53 (2008).
    • (2008) Nat. Immunol. , vol.9 , pp. 42-53
    • Ledgerwood, L.G.1
  • 35
    • 79959541003 scopus 로고    scopus 로고
    • The 'ins' and 'outs' of podosomes and invadopodia: Characteristics, formation and function
    • Murphy, D.A. & Courtneidge, S.A. The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function. Nat. Rev. Mol. Cell Biol. 12, 413-426 (2011).
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 413-426
    • Murphy, D.A.1    Courtneidge, S.A.2
  • 36
    • 0021972672 scopus 로고
    • Endothelial fenestral diaphragms: A quick-freeze, deep-etch study
    • Bearer, E.L. & Orci, L. Endothelial fenestral diaphragms: a quick-freeze, deep-etch study. J. Cell Biol. 100, 418-428 (1985).
    • (1985) J. Cell Biol. , vol.100 , pp. 418-428
    • Bearer, E.L.1    Orci, L.2
  • 37
    • 0024989722 scopus 로고
    • Lectin analysis of common glycoproteins detected on the surface of continuous microvascular endothelium in situ and in culture: Identification of sialoglycoproteins
    • Schnitzer, J.E., Shen, C.P. & Palade, G.E. Lectin analysis of common glycoproteins detected on the surface of continuous microvascular endothelium in situ and in culture: identification of sialoglycoproteins. Eur. J. Cell Biol. 52, 241-251 (1990).
    • (1990) Eur. J. Cell Biol. , vol.52 , pp. 241-251
    • Schnitzer, J.E.1    Shen, C.P.2    Palade, G.E.3
  • 38
    • 84859926294 scopus 로고    scopus 로고
    • Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks
    • Malhotra, D. et al. Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks. Nat. Immunol. 13, 499-510 (2012).
    • (2012) Nat. Immunol. , vol.13 , pp. 499-510
    • Malhotra, D.1
  • 39
    • 33751528001 scopus 로고    scopus 로고
    • An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium
    • Johnson, L.A. et al. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium. J. Exp. Med. 203, 2763-2777 (2006).
    • (2006) J. Exp. Med. , vol.203 , pp. 2763-2777
    • Johnson, L.A.1
  • 40
    • 51149089536 scopus 로고    scopus 로고
    • Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node
    • Pfeiffer, F. et al. Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node. Eur. J. Immunol. 38, 2142-2155 (2008).
    • (2008) Eur. J. Immunol. , vol.38 , pp. 2142-2155
    • Pfeiffer, F.1
  • 41
    • 34948814992 scopus 로고    scopus 로고
    • Functionally specialized junctions between endothelial cells of lymphatic vessels
    • Baluk, P. et al. Functionally specialized junctions between endothelial cells of lymphatic vessels. J. Exp. Med. 204, 2349-2362 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 2349-2362
    • Baluk, P.1
  • 42
    • 34250168972 scopus 로고    scopus 로고
    • Transcellular diapedesis is initiated by invasive podosomes
    • Carman, C.V. et al. Transcellular diapedesis is initiated by invasive podosomes. Immunity 26, 784-797 (2007).
    • (2007) Immunity , vol.26 , pp. 784-797
    • Carman, C.V.1
  • 43
    • 84906876093 scopus 로고    scopus 로고
    • Probing the biomechanical contribution of the endothelium to lymphocyte migration: Diapedesis by the path of least resistance
    • Martinelli, R. et al. Probing the biomechanical contribution of the endothelium to lymphocyte migration: diapedesis by the path of least resistance. J. Cell Sci. 127, 3720-3734 (2014).
    • (2014) J. Cell Sci. , vol.127 , pp. 3720-3734
    • Martinelli, R.1
  • 44
    • 0031874849 scopus 로고    scopus 로고
    • Improved properties of FLP recombinase evolved by cycling mutagenesis
    • Buchholz, F., Angrand, P.O. & Stewart, A.F. Improved properties of FLP recombinase evolved by cycling mutagenesis. Nat. Biotechnol. 16, 657-662 (1998).
    • (1998) Nat. Biotechnol. , vol.16 , pp. 657-662
    • Buchholz, F.1    Angrand, P.O.2    Stewart, A.F.3
  • 46
    • 0031577470 scopus 로고    scopus 로고
    • A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission
    • Sakai, K. & Miyazaki, J. A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission. Biochem. Biophys. Res. Commun. 237, 318-324 (1997).
    • (1997) Biochem. Biophys. Res. Commun. , vol.237 , pp. 318-324
    • Sakai, K.1    Miyazaki, J.2
  • 47
    • 84863586073 scopus 로고    scopus 로고
    • PV-1 is recognized by the PAL-E antibody and forms complexes with NRP-1
    • Keuschnigg, J. et al. PV-1 is recognized by the PAL-E antibody and forms complexes with NRP-1. Blood 120, 232-235 (2012).
    • (2012) Blood , vol.120 , pp. 232-235
    • Keuschnigg, J.1
  • 48
    • 84872435502 scopus 로고    scopus 로고
    • Interstitial dendritic cell guidance by haptotactic chemokine gradients
    • Weber, M. et al. Interstitial dendritic cell guidance by haptotactic chemokine gradients. Science 339, 328-332 (2013).
    • (2013) Science , vol.339 , pp. 328-332
    • Weber, M.1
  • 49
    • 84863181231 scopus 로고    scopus 로고
    • Whole-mount three-dimensional imaging of internally localized immunostained cells within mouse embryos
    • Yokomizo, T. et al. Whole-mount three-dimensional imaging of internally localized immunostained cells within mouse embryos. Nat. Protoc. 7, 421-431 (2012).
    • (2012) Nat. Protoc. , vol.7 , pp. 421-431
    • Yokomizo, T.1


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