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Volumn 9, Issue 5, 2017, Pages

Fructose, glucocorticoids and adipose tissue: Implications for the metabolic syndrome

Author keywords

Adipogenesis; Fructose; Glucocorticoid; Metabolic syndrome; Obesity

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; FRUCTOSE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUCOSE TRANSPORTER 5; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; MINERALOCORTICOID RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; TRIACYLGLYCEROL; HSD11B1 PROTEIN, HUMAN;

EID: 85018313995     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu9050426     Document Type: Review
Times cited : (38)

References (149)
  • 1
    • 84942576978 scopus 로고    scopus 로고
    • Fructose and Cardiometabolic Health: What the Evidence from Sugar-Sweetened Beverages Tells Us
    • Malik, V.S., Hu, F.B. Fructose and Cardiometabolic Health: What the Evidence from Sugar-Sweetened Beverages Tells Us. J. Am. Coll. Cardiol. 2015, 66, 1615-1624.
    • (2015) J. Am. Coll. Cardiol , vol.66 , pp. 1615-1624
    • Malik, V.S.1    Hu, F.B.2
  • 3
    • 77949809397 scopus 로고    scopus 로고
    • Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and cardiovascular disease risk
    • Malik, V.S., Popkin, B.M., Bray, G.A., Despres, J.P., Hu, F.B. Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and cardiovascular disease risk. Circulation 2010, 121, 1356-1364.
    • (2010) Circulation , vol.121 , pp. 1356-1364
    • Malik, V.S.1    Popkin, B.M.2    Bray, G.A.3    Despres, J.P.4    Hu, F.B.5
  • 4
    • 78650920491 scopus 로고    scopus 로고
    • Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: A meta-analysis
    • Malik, V.S., Popkin, B.M., Bray, G.A., Despres, J.P., Willett, W.C., Hu, F.B. Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: A meta-analysis. Diabetes Care 2010, 33, 2477-2483.
    • (2010) Diabetes Care , vol.33 , pp. 2477-2483
    • Malik, V.S.1    Popkin, B.M.2    Bray, G.A.3    Despres, J.P.4    Willett, W.C.5    Hu, F.B.6
  • 5
    • 0003017775 scopus 로고
    • Levels of Dietary Sucrose in Patients with Occlusive Atherosclerotic Disease
    • Yudkin, J., Roddy, J. Levels of Dietary Sucrose in Patients with Occlusive Atherosclerotic Disease. Lancet 1964, 2, 6-8.
    • (1964) Lancet , vol.2 , pp. 6-8
    • Yudkin, J.1    Roddy, J.2
  • 6
    • 0022965159 scopus 로고
    • Metabolic effects of dietary fructose and sucrose in types I and II diabetic subjects
    • Bantle, J.P., Laine, D.C., Thomas, J.W. Metabolic effects of dietary fructose and sucrose in types I and II diabetic subjects. JAMA 1986, 256, 3241-3246.
    • (1986) JAMA , vol.256 , pp. 3241-3246
    • Bantle, J.P.1    Laine, D.C.2    Thomas, J.W.3
  • 7
    • 33845886915 scopus 로고    scopus 로고
    • Abdominal obesity and metabolic syndrome
    • Despres, J.P., Lemieux, I. Abdominal obesity and metabolic syndrome. Nature 2006, 444, 881-887.
    • (2006) Nature , vol.444 , pp. 881-887
    • Despres, J.P.1    Lemieux, I.2
  • 8
    • 80054911514 scopus 로고    scopus 로고
    • Forming functional fat: A growing understanding of adipocyte differentiation
    • Cristancho, A.G., Lazar, M.A. Forming functional fat: A growing understanding of adipocyte differentiation. Nat. Rev. Mol. Cell Biol. 2011, 12, 722-734.
    • (2011) Nat. Rev. Mol. Cell Biol , vol.12 , pp. 722-734
    • Cristancho, A.G.1    Lazar, M.A.2
  • 9
    • 84872290190 scopus 로고    scopus 로고
    • Hypoxia and adipose tissue function and dysfunction in obesity
    • Trayhurn, P. Hypoxia and adipose tissue function and dysfunction in obesity. Physiol. Rev. 2013, 93, 1-21.
    • (2013) Physiol. Rev , vol.93 , pp. 1-21
    • Trayhurn, P.1
  • 10
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil, G.S. Inflammation and metabolic disorders. Nature 2006, 444, 860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 12
    • 0027425939 scopus 로고
    • Intakes and food sources of fructose in the United States
    • Park, Y.K., Yetley, E.A. Intakes and food sources of fructose in the United States. Am. J. Clin. Nutr. 1993, 58 (Suppl 5), 737S-747S.
    • (1993) Am. J. Clin. Nutr , vol.58 , pp. 737S-747S
    • Park, Y.K.1    Yetley, E.A.2
  • 13
    • 49449098216 scopus 로고    scopus 로고
    • Dietary fructose consumption among US children and adults: The Third National Health and Nutrition Examination Survey
    • Vos, M.B., Kimmons, J.E., Gillespie, C., Welsh, J., Blanck, H.M. Dietary fructose consumption among US children and adults: The Third National Health and Nutrition Examination Survey. Medscape J. Med. 2008, 10, 160.
    • (2008) Medscape J. Med , vol.10 , pp. 160
    • Vos, M.B.1    Kimmons, J.E.2    Gillespie, C.3    Welsh, J.4    Blanck, H.M.5
  • 14
    • 2142815151 scopus 로고    scopus 로고
    • Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity
    • Bray, G.A., Nielsen, S.J., Popkin, B.M. Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. Am. J. Clin. Nutr. 2004, 79, 537-543.
    • (2004) Am. J. Clin. Nutr , vol.79 , pp. 537-543
    • Bray, G.A.1    Nielsen, S.J.2    Popkin, B.M.3
  • 15
    • 38149042079 scopus 로고    scopus 로고
    • Fructose consumption: Potential mechanisms for its effects to increase visceral adiposity and induce dyslipidemia and insulin resistance
    • Stanhope, K.L., Havel, P.J. Fructose consumption: Potential mechanisms for its effects to increase visceral adiposity and induce dyslipidemia and insulin resistance. Curr. Opin. Lipidol. 2008, 19, 16-24.
    • (2008) Curr. Opin. Lipidol , vol.19 , pp. 16-24
    • Stanhope, K.L.1    Havel, P.J.2
  • 16
    • 75149166672 scopus 로고    scopus 로고
    • Metabolic effects of fructose and the worldwide increase in obesity
    • Tappy, L., Le, K.A. Metabolic effects of fructose and the worldwide increase in obesity. Physiol. Rev. 2010, 90, 23-46.
    • (2010) Physiol. Rev , vol.90 , pp. 23-46
    • Tappy, L.1    Le, K.A.2
  • 17
    • 23944443756 scopus 로고    scopus 로고
    • Hepatic adaptations to sucrose and fructose
    • Bizeau, M.E., Pagliassotti, M.J. Hepatic adaptations to sucrose and fructose. Metabolism 2005, 54, 1189-1201.
    • (2005) Metabolism , vol.54 , pp. 1189-1201
    • Bizeau, M.E.1    Pagliassotti, M.J.2
  • 18
    • 0027451819 scopus 로고
    • Manufacturing, composition, and applications of fructose
    • Hanover, L.M., White, J.S. Manufacturing, composition, and applications of fructose. Am. J. Clin. Nutr. 1993, 58 (Suppl 5), 724S-732S.
    • (1993) Am. J. Clin. Nutr , vol.58 , pp. 724S-732S
    • Hanover, L.M.1    White, J.S.2
  • 19
    • 84962142447 scopus 로고    scopus 로고
    • Long-Term Fructose Intake Increases Adipogenic Potential: Evidence of Direct Effects of Fructose on Adipocyte Precursor Cells
    • Zubiria, M.G., Alzamendi, A., Moreno, G., Rey, M.A., Spinedi, E., Giovambattista, A. Long-Term Fructose Intake Increases Adipogenic Potential: Evidence of Direct Effects of Fructose on Adipocyte Precursor Cells. Nutrients 2016, 8, 198.
    • (2016) Nutrients , vol.8 , pp. 198
    • Zubiria, M.G.1    Alzamendi, A.2    Moreno, G.3    Rey, M.A.4    Spinedi, E.5    Giovambattista, A.6
  • 21
    • 58149330675 scopus 로고    scopus 로고
    • Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity
    • Tomlinson, J.W., Finney, J., Gay, C., Hughes, B.A., Hughes, S.V., Stewart, P.M. Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity. Diabetes 2008, 57, 2652-2660.
    • (2008) Diabetes , vol.57 , pp. 2652-2660
    • Tomlinson, J.W.1    Finney, J.2    Gay, C.3    Hughes, B.A.4    Hughes, S.V.5    Stewart, P.M.6
  • 22
    • 72449133267 scopus 로고    scopus 로고
    • Obesity and corticosteroids: 11beta-hydroxysteroid type 1 as a cause and therapeutic target in metabolic disease
    • Morton, N.M. Obesity and corticosteroids: 11beta-hydroxysteroid type 1 as a cause and therapeutic target in metabolic disease. Mol. Cell Endocrinol. 2010, 316, 154-164.
    • (2010) Mol. Cell Endocrinol , vol.316 , pp. 154-164
    • Morton, N.M.1
  • 23
    • 79955471278 scopus 로고    scopus 로고
    • High fructose diets increase 11beta-hydroxysteroid dehydrogenase type 1 in liver and visceral adipose in rats within 24-h exposure
    • London, E., Castonguay, T.W. High fructose diets increase 11beta-hydroxysteroid dehydrogenase type 1 in liver and visceral adipose in rats within 24-h exposure. Obesity 2011, 19, 925-932.
    • (2011) Obesity , vol.19 , pp. 925-932
    • London, E.1    Castonguay, T.W.2
  • 24
    • 47849106043 scopus 로고    scopus 로고
    • Modification of microsomal 11beta-HSD1 activity by cytosolic compounds: Glutathione and hexose phosphoesters
    • McCormick, K.L., Wang, X., Mick, G.J. Modification of microsomal 11beta-HSD1 activity by cytosolic compounds: Glutathione and hexose phosphoesters. J. Steroid. Biochem. Mol. Biol. 2008, 111, 18-23.
    • (2008) J. Steroid. Biochem. Mol. Biol , vol.111 , pp. 18-23
    • McCormick, K.L.1    Wang, X.2    Mick, G.J.3
  • 25
    • 77957258654 scopus 로고    scopus 로고
    • Contribution of fructose-6-phosphate to glucocorticoid activation in the endoplasmic reticulum: Possible implication in the metabolic syndrome
    • Senesi, S., Legeza, B., Balazs, Z., Csala, M., Marcolongo, P., Kereszturi, E., Szelenyi, P., Egger, C., Fulceri, R., Mandl, J., et al. Contribution of fructose-6-phosphate to glucocorticoid activation in the endoplasmic reticulum: Possible implication in the metabolic syndrome. Endocrinology 2010, 151, 4830-4839.
    • (2010) Endocrinology , vol.151 , pp. 4830-4839
    • Senesi, S.1    Legeza, B.2    Balazs, Z.3    Csala, M.4    Marcolongo, P.5    Kereszturi, E.6    Szelenyi, P.7    Egger, C.8    Fulceri, R.9    Mandl, J.10
  • 26
    • 76749133138 scopus 로고    scopus 로고
    • 11beta-Hydroxysteroid dehydrogenase type 1 is an important regulator at the interface of obesity and inflammation
    • Staab, C.A., Maser, E. 11beta-Hydroxysteroid dehydrogenase type 1 is an important regulator at the interface of obesity and inflammation. J. Steroid Biochem. Mol. Biol. 2010, 119, 56-72.
    • (2010) J. Steroid Biochem. Mol. Biol , vol.119 , pp. 56-72
    • Staab, C.A.1    Maser, E.2
  • 27
    • 84893648934 scopus 로고    scopus 로고
    • Deconstructing the roles of glucocorticoids in adipose tissue biology and the development of central obesity
    • Lee, M.J., Pramyothin, P., Karastergiou, K., Fried, S.K. Deconstructing the roles of glucocorticoids in adipose tissue biology and the development of central obesity. Biochim. Biophys. Acta 2014, 1842, 473-481.
    • (2014) Biochim. Biophys. Acta , vol.1842 , pp. 473-481
    • Lee, M.J.1    Pramyothin, P.2    Karastergiou, K.3    Fried, S.K.4
  • 28
    • 3042595899 scopus 로고    scopus 로고
    • Cooperativity between 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the lumen of the endoplasmic reticulum
    • Banhegyi, G., Benedetti, A., Fulceri, R., Senesi, S. Cooperativity between 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the lumen of the endoplasmic reticulum. J. Biol. Chem. 2004, 279, 27017-27021.
    • (2004) J. Biol. Chem , vol.279 , pp. 27017-27021
    • Banhegyi, G.1    Benedetti, A.2    Fulceri, R.3    Senesi, S.4
  • 29
    • 3342998410 scopus 로고    scopus 로고
    • Hexose-6-phosphate dehydrogenase determines the reaction direction of 11beta-hydroxysteroid dehydrogenase type 1 as an oxoreductase
    • Atanasov, A.G., Nashev, L.G., Schweizer, R.A., Frick, C., Odermatt, A. Hexose-6-phosphate dehydrogenase determines the reaction direction of 11beta-hydroxysteroid dehydrogenase type 1 as an oxoreductase. FEBS Lett. 2004, 571, 129-133.
    • (2004) FEBS Lett , vol.571 , pp. 129-133
    • Atanasov, A.G.1    Nashev, L.G.2    Schweizer, R.A.3    Frick, C.4    Odermatt, A.5
  • 30
    • 0033214482 scopus 로고    scopus 로고
    • The N-terminal anchor sequences of 11beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane
    • Odermatt, A., Arnold, P., Stauffer, A., Frey, B.M., Frey, F.J. The N-terminal anchor sequences of 11beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane. J. Biol. Chem. 1999, 274, 28762-28770.
    • (1999) J. Biol. Chem , vol.274 , pp. 28762-28770
    • Odermatt, A.1    Arnold, P.2    Stauffer, A.3    Frey, B.M.4    Frey, F.J.5
  • 31
    • 0028899788 scopus 로고
    • Lumenal orientation and post-translational modifications of the liver microsomal 11 beta-hydroxysteroid dehydrogenase
    • Ozols, J. Lumenal orientation and post-translational modifications of the liver microsomal 11 beta-hydroxysteroid dehydrogenase. J. Biol. Chem. 1995, 270, 2305-2312.
    • (1995) J. Biol. Chem , vol.270 , pp. 2305-2312
    • Ozols, J.1
  • 32
    • 84856335862 scopus 로고    scopus 로고
    • Tissue-specific modulation of mineralocorticoid receptor function by 11beta-hydroxysteroid dehydrogenases: An overview
    • Odermatt, A., Kratschmar, D.V. Tissue-specific modulation of mineralocorticoid receptor function by 11beta-hydroxysteroid dehydrogenases: An overview. Mol. Cell Endocrinol. 2012, 350, 168-186.
    • (2012) Mol. Cell Endocrinol. , vol.350 , pp. 168-186
    • Odermatt, A.1    Kratschmar, D.V.2
  • 34
    • 13944255183 scopus 로고    scopus 로고
    • 11beta-hydroxysteroid dehydrogenases: Changing glucocorticoid action
    • Seckl, J.R. 11beta-hydroxysteroid dehydrogenases: Changing glucocorticoid action. Curr. Opin. Pharmacol. 2004, 4, 597-602.
    • (2004) Curr. Opin. Pharmacol , vol.4 , pp. 597-602
    • Seckl, J.R.1
  • 35
    • 84892786016 scopus 로고    scopus 로고
    • Fructose promotes the differentiation of 3T3-L1 adipocytes and accelerates lipid metabolism
    • Legeza, B., Balazs, Z., Odermatt, A. Fructose promotes the differentiation of 3T3-L1 adipocytes and accelerates lipid metabolism. FEBS Lett. 2014, 588, 490-496.
    • (2014) FEBS Lett , vol.588 , pp. 490-496
    • Legeza, B.1    Balazs, Z.2    Odermatt, A.3
  • 37
    • 84874524849 scopus 로고    scopus 로고
    • The relationship of sugar to population-level diabetes prevalence: An econometric analysis of repeated cross-sectional data
    • Basu, S., Yoffe, P., Hills, N., Lustig, R.H. The relationship of sugar to population-level diabetes prevalence: An econometric analysis of repeated cross-sectional data. PLoS ONE 2013, 8, e57873.
    • (2013) Plos ONE , vol.8
    • Basu, S.1    Yoffe, P.2    Hills, N.3    Lustig, R.H.4
  • 40
    • 35148825449 scopus 로고    scopus 로고
    • Potential role of sugar (Fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease
    • Johnson, R.J., Segal, M.S., Sautin, Y., Nakagawa, T., Feig, D.I., Kang, D.H., Gersch, M.S., Benner, S., Sanchez-Lozada, L.G. Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease. Am. J. Clin. Nutr. 2007, 86, 899-906.
    • (2007) Am. J. Clin. Nutr , vol.86 , pp. 899-906
    • Johnson, R.J.1    Segal, M.S.2    Sautin, Y.3    Nakagawa, T.4    Feig, D.I.5    Kang, D.H.6    Gersch, M.S.7    Benner, S.8    Sanchez-Lozada, L.G.9
  • 41
    • 0030907827 scopus 로고    scopus 로고
    • Excess fruit juice consumption by preschool-aged children is associated with short stature and obesity
    • Dennison, B.A., Rockwell, H.L., Baker, S.L. Excess fruit juice consumption by preschool-aged children is associated with short stature and obesity. Pediatrics 1997, 99, 15-22.
    • (1997) Pediatrics , vol.99 , pp. 15-22
    • Dennison, B.A.1    Rockwell, H.L.2    Baker, S.L.3
  • 42
    • 0035901051 scopus 로고    scopus 로고
    • Relation between consumption of sugar-sweetened drinks and childhood obesity: A prospective, observational analysis
    • Ludwig, D.S., Peterson, K.E., Gortmaker, S.L. Relation between consumption of sugar-sweetened drinks and childhood obesity: A prospective, observational analysis. Lancet 2001, 357, 505-508.
    • (2001) Lancet , vol.357 , pp. 505-508
    • Ludwig, D.S.1    Peterson, K.E.2    Gortmaker, S.L.3
  • 43
    • 4143067005 scopus 로고    scopus 로고
    • Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women
    • Schulze, M.B., Manson, J.E., Ludwig, D.S., Colditz, G.A., Stampfer, M.J., Willett, W.C., Hu, F.B. Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women. JAMA 2004, 292, 927-934.
    • (2004) JAMA , vol.292 , pp. 927-934
    • Schulze, M.B.1    Manson, J.E.2    Ludwig, D.S.3    Colditz, G.A.4    Stampfer, M.J.5    Willett, W.C.6    Hu, F.B.7
  • 44
    • 84954348953 scopus 로고    scopus 로고
    • Fox, Sugar-Sweetened Beverage Consumption Is Associated With Change of Visceral Adipose Tissue Over 6 Years of Follow-Up
    • Ma, J., McKeown, N.M., Hwang, S.J., Hoffmann, U., Jacques, P.F.C.S. Fox, Sugar-Sweetened Beverage Consumption Is Associated With Change of Visceral Adipose Tissue Over 6 Years of Follow-Up. Circulation 2016, 133, 370-377.
    • (2016) Circulation , vol.133 , pp. 370-377
    • Ma, J.1    McKeown, N.M.2    Hwang, S.J.3    Hoffmann, U.4    Jacques, P.F.C.S.5
  • 45
    • 66449093225 scopus 로고    scopus 로고
    • Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans
    • Stanhope, K.L., Schwarz, J.M., Keim, N.L., Griffen, S.C., Bremer, A.A., Graham, J.L., Hatcher, B., Cox, C.L., Dyachenko, A., Zhang, W., et al. Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. J. Clin. Investig. 2009, 119, 1322-1334.
    • (2009) J. Clin. Investig , vol.119 , pp. 1322-1334
    • Stanhope, K.L.1    Schwarz, J.M.2    Keim, N.L.3    Griffen, S.C.4    Bremer, A.A.5    Graham, J.L.6    Hatcher, B.7    Cox, C.L.8    Dyachenko, A.9    Zhang, W.10
  • 49
    • 10744228031 scopus 로고    scopus 로고
    • Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice
    • Matsuzaka, T., Shimano, H., Yahagi, N., Amemiya-Kudo, M., Okazaki, H., Tamura, Y., Iizuka, Y., Ohashi, K., Tomita, S., Sekiya, M., et al. Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice. Diabetes 2004, 53, 560-569.
    • (2004) Diabetes , vol.53 , pp. 560-569
    • Matsuzaka, T.1    Shimano, H.2    Yahagi, N.3    Amemiya-Kudo, M.4    Okazaki, H.5    Tamura, Y.6    Iizuka, Y.7    Ohashi, K.8    Tomita, S.9    Sekiya, M.10
  • 50
    • 0033744888 scopus 로고    scopus 로고
    • Effects of dietary fructose on plasma lipids in healthy subjects
    • Bantle, J.P., Raatz, S.K., Thomas, W., Georgopoulos, A. Effects of dietary fructose on plasma lipids in healthy subjects. Am. J. Clin. Nutr. 2000, 72, 1128-1134.
    • (2000) Am. J. Clin. Nutr , vol.72 , pp. 1128-1134
    • Bantle, J.P.1    Raatz, S.K.2    Thomas, W.3    Georgopoulos, A.4
  • 51
    • 0026795501 scopus 로고
    • Metabolic effects of dietary fructose in diabetic subjects
    • Bantle, J.P., Swanson, J.E., Thomas, W., Laine, D.C. Metabolic effects of dietary fructose in diabetic subjects. Diabetes Care 1992, 15, 1468-1476.
    • (1992) Diabetes Care , vol.15 , pp. 1468-1476
    • Bantle, J.P.1    Swanson, J.E.2    Thomas, W.3    Laine, D.C.4
  • 53
    • 33845482041 scopus 로고    scopus 로고
    • 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans
    • Le, K.A., Faeh, D., Stettler, R., Ith, M., Kreis, R., Vermathen, P., Boesch, C., Ravussin, E., Tappy, L. A 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans. Am. J. Clin. Nutr. 2006, 84, 1374-1379.
    • (2006) Am. J. Clin. Nutr , vol.84 , pp. 1374-1379
    • Le, K.A.1    Faeh, D.2    Stettler, R.3    Ith, M.4    Kreis, R.5    Vermathen, P.6    Boesch, C.7    Ravussin, E.8    Tappy, L.A.9
  • 54
    • 66849124938 scopus 로고    scopus 로고
    • Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes
    • Le, K.A., Ith, M., Kreis, R., Faeh, D., Bortolotti, M., Tran, C., Boesch, C., Tappy, L. Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes. Am. J. Clin. Nutr. 2009, 89, 1760-1765.
    • (2009) Am. J. Clin. Nutr , vol.89 , pp. 1760-1765
    • Le, K.A.1    Ith, M.2    Kreis, R.3    Faeh, D.4    Bortolotti, M.5    Tran, C.6    Boesch, C.7    Tappy, L.8
  • 56
    • 80052200625 scopus 로고    scopus 로고
    • Fructose-fed rhesus monkeys: A nonhuman primate model of insulin resistance, metabolic syndrome, and type 2 diabetes
    • Bremer, A.A., Stanhope, K.L., Graham, J.L., Cummings, B.P., Wang, W., Saville, B.R., Havel, P.J. Fructose-fed rhesus monkeys: A nonhuman primate model of insulin resistance, metabolic syndrome, and type 2 diabetes. Clin. Transl. Sci. 2011, 4, 243-252.
    • (2011) Clin. Transl. Sci , vol.4 , pp. 243-252
    • Bremer, A.A.1    Stanhope, K.L.2    Graham, J.L.3    Cummings, B.P.4    Wang, W.5    Saville, B.R.6    Havel, P.J.7
  • 58
    • 0027364672 scopus 로고
    • Intermediary metabolism of fructose
    • Mayes, P.A. Intermediary metabolism of fructose. Am. J. Clin. Nutr. 1993, 58, 754S-765S.
    • (1993) Am. J. Clin. Nutr , vol.58 , pp. 754S-765S
    • Mayes, P.A.1
  • 59
    • 52649098968 scopus 로고    scopus 로고
    • Regulation of the fructose transporter GLUT5 in health and disease
    • Douard, V., Ferraris, R.P. Regulation of the fructose transporter GLUT5 in health and disease. Am. J. Physiol. Endocrinol. Metab. 2008, 295, E227-E237.
    • (2008) Am. J. Physiol. Endocrinol. Metab. , vol.295 , pp. E227-E237
    • Douard, V.1    Ferraris, R.P.2
  • 60
    • 0031809969 scopus 로고    scopus 로고
    • Fructose uptake in rat adipocytes: GLUT5 expression and the effects of streptozotocin-induced diabetes
    • Hajduch, E., Darakhshan, F., Hundal, H.S. Fructose uptake in rat adipocytes: GLUT5 expression and the effects of streptozotocin-induced diabetes. Diabetologia 1998, 41, 821-828.
    • (1998) Diabetologia , vol.41 , pp. 821-828
    • Hajduch, E.1    Darakhshan, F.2    Hundal, H.S.3
  • 61
    • 84867007389 scopus 로고    scopus 로고
    • Regulation of adipose differentiation by fructose and GluT5
    • Du, L., Heaney, A.P. Regulation of adipose differentiation by fructose and GluT5. Mol. Endocrinol. 2012, 26, 1773-1782.
    • (2012) Mol. Endocrinol , vol.26 , pp. 1773-1782
    • Du, L.1    Heaney, A.P.2
  • 62
    • 0015452391 scopus 로고
    • Fructose metabolism in adipose tissue
    • Froesch, E.R. Fructose metabolism in adipose tissue. Acta Med. Scand. Suppl. 1972, 542, 37-46.
    • (1972) Acta Med. Scand. Suppl , vol.542 , pp. 37-46
    • Froesch, E.R.1
  • 63
    • 84939886039 scopus 로고    scopus 로고
    • Metabolic fate of fructose in human adipocytes: A targeted 13C tracer fate association study
    • Varma, V., Boros, L.G., Nolen, G.T., Chang, C.W., Wabitsch, M., Beger, R.D., Kaput, J. Metabolic fate of fructose in human adipocytes: A targeted 13C tracer fate association study. Metabolomics 2015, 11, 529-544.
    • (2015) Metabolomics , vol.11 , pp. 529-544
    • Varma, V.1    Boros, L.G.2    Nolen, G.T.3    Chang, C.W.4    Wabitsch, M.5    Beger, R.D.6    Kaput, J.7
  • 64
    • 85016852457 scopus 로고    scopus 로고
    • Fructose Alters Intermediary Metabolism of Glucose in Human Adipocytes and Diverts Glucose to Serine Oxidation in the One-Carbon Cycle Energy Producing Pathway
    • Varma, V., Boros, L.G., Nolen, G.T., Chang, C.W., Wabitsch, M., Beger, R.D., Kaput, J. Fructose Alters Intermediary Metabolism of Glucose in Human Adipocytes and Diverts Glucose to Serine Oxidation in the One-Carbon Cycle Energy Producing Pathway. Metabolites 2015, 5, 364-385.
    • (2015) Metabolites , vol.5 , pp. 364-385
    • Varma, V.1    Boros, L.G.2    Nolen, G.T.3    Chang, C.W.4    Wabitsch, M.5    Beger, R.D.6    Kaput, J.7
  • 67
    • 77953165671 scopus 로고    scopus 로고
    • Fuel selection and cycling endurance performance with ingestion of [13C]glucose: Evidence for a carbohydrate dose response
    • Smith, J.W., Zachwieja, J.J., Peronnet, F., Passe, D.H., Massicotte, D., Lavoie, C., Pascoe, D.D. Fuel selection and cycling endurance performance with ingestion of [13C]glucose: Evidence for a carbohydrate dose response. J. Appl. Physiol. 2010, 108, 1520-1529.
    • (2010) J. Appl. Physiol , vol.108 , pp. 1520-1529
    • Smith, J.W.1    Zachwieja, J.J.2    Peronnet, F.3    Passe, D.H.4    Massicotte, D.5    Lavoie, C.6    Pascoe, D.D.7
  • 69
    • 84860425068 scopus 로고    scopus 로고
    • Composite versus single transportable carbohydrate solution enhances race and laboratory cycling performance
    • Rowlands, D.S., Swift, M., Ros, M., Green, J.G. Composite versus single transportable carbohydrate solution enhances race and laboratory cycling performance. Appl. Physiol. Nutr. Metab. 2012, 37, 425-436.
    • (2012) Appl. Physiol. Nutr. Metab , vol.37 , pp. 425-436
    • Rowlands, D.S.1    Swift, M.2    Ros, M.3    Green, J.G.4
  • 71
    • 78149301826 scopus 로고    scopus 로고
    • Fructose and glucose co-ingestion during prolonged exercise increases lactate and glucose fluxes and oxidation compared with an equimolar intake of glucose
    • Lecoultre, V., Benoit, R., Carrel, G., Schutz, Y., Millet, G.P., Tappy, L., Schneiter, P. Fructose and glucose co-ingestion during prolonged exercise increases lactate and glucose fluxes and oxidation compared with an equimolar intake of glucose. Am. J. Clin. Nutr. 2010, 92, 1071-1079.
    • (2010) Am. J. Clin. Nutr , vol.92 , pp. 1071-1079
    • Lecoultre, V.1    Benoit, R.2    Carrel, G.3    Schutz, Y.4    Millet, G.P.5    Tappy, L.6    Schneiter, P.7
  • 72
    • 0015233148 scopus 로고
    • Effects of fructose infusion on lactate and uric acid metabolism
    • Sahebjami, H., Scalettar, R. Effects of fructose infusion on lactate and uric acid metabolism. Lancet 1971, 1, 366-369.
    • (1971) Lancet , vol.1 , pp. 366-369
    • Sahebjami, H.1    Scalettar, R.2
  • 73
    • 0031821520 scopus 로고    scopus 로고
    • Understanding adipocyte differentiation
    • Gregoire, F.M., Smas, C.M., Sul, H.S. Understanding adipocyte differentiation. Physiol. Rev. 1998, 78, 783-809.
    • (1998) Physiol. Rev , vol.78 , pp. 783-809
    • Gregoire, F.M.1    Smas, C.M.2    Sul, H.S.3
  • 74
    • 84926992167 scopus 로고    scopus 로고
    • The glucocorticoid receptor, not the mineralocorticoid receptor, plays the dominant role in adipogenesis and adipokine production in human adipocytes
    • Lee, M.J., Fried, S.K. The glucocorticoid receptor, not the mineralocorticoid receptor, plays the dominant role in adipogenesis and adipokine production in human adipocytes. Int. J. Obes. (Lond.) 2014, 38, 1228-1233.
    • (2014) Int. J. Obes. (Lond.) , vol.38 , pp. 1228-1233
    • Lee, M.J.1    Fried, S.K.2
  • 76
    • 77954364477 scopus 로고    scopus 로고
    • Pref-1 interacts with fibronectin to inhibit adipocyte differentiation
    • Wang, Y., Zhao, L., Smas, C., Sul, H.S. Pref-1 interacts with fibronectin to inhibit adipocyte differentiation. Mol. Cell Biol. 2010, 30, 3480-3492.
    • (2010) Mol. Cell Biol , vol.30 , pp. 3480-3492
    • Wang, Y.1    Zhao, L.2    Smas, C.3    Sul, H.S.4
  • 79
    • 84952360558 scopus 로고    scopus 로고
    • Fructose-derived advanced glycation end-products drive lipogenesis and skeletal muscle reprogramming via SREBP-1c dysregulation in mice
    • Mastrocola, R., Nigro, D., Chiazza, F., Medana, C., Bello, F.D., Boccuzzi, G., Collino, M., Aragno, M. Fructose-derived advanced glycation end-products drive lipogenesis and skeletal muscle reprogramming via SREBP-1c dysregulation in mice. Free Radic. Biol. Med. 2016, 91, 224-235.
    • (2016) Free Radic. Biol. Med , vol.91 , pp. 224-235
    • Mastrocola, R.1    Nigro, D.2    Chiazza, F.3    Medana, C.4    Bello, F.D.5    Boccuzzi, G.6    Collino, M.7    Aragno, M.8
  • 80
    • 84896119824 scopus 로고    scopus 로고
    • Extra fructose in the growth medium fuels lipogenesis of adipocytes
    • Robubi, A., Huber, K.R., Krugluger, W. Extra fructose in the growth medium fuels lipogenesis of adipocytes. J. Obes. 2014, 2014, 647034.
    • (2014) J. Obes , vol.2014
    • Robubi, A.1    Huber, K.R.2    Krugluger, W.3
  • 81
    • 84989843226 scopus 로고    scopus 로고
    • High-fructose diet is as detrimental as high-fat diet in the induction of insulin resistance and diabetes mediated by hepatic/pancreatic endoplasmic reticulum (ER) stress
    • Balakumar, M., Raji, L., Prabhu, D., Sathishkumar, C., Prabu, P., Mohan, V., Balasubramanyam, M. High-fructose diet is as detrimental as high-fat diet in the induction of insulin resistance and diabetes mediated by hepatic/pancreatic endoplasmic reticulum (ER) stress. Mol. Cell Biochem. 2016, 423, 93-104.
    • (2016) Mol. Cell Biochem , vol.423 , pp. 93-104
    • Balakumar, M.1    Raji, L.2    Prabhu, D.3    Sathishkumar, C.4    Prabu, P.5    Mohan, V.6    Balasubramanyam, M.7
  • 82
    • 77953868236 scopus 로고    scopus 로고
    • Lipid-induced insulin resistance: Unravelling the mechanism
    • Samuel, V.T., Petersen, K.F., Shulman, G.I. Lipid-induced insulin resistance: Unravelling the mechanism. Lancet 2010, 375, 2267-2277.
    • (2010) Lancet , vol.375 , pp. 2267-2277
    • Samuel, V.T.1    Petersen, K.F.2    Shulman, G.I.3
  • 84
    • 84887591021 scopus 로고    scopus 로고
    • The rate of production of uric acid by hepatocytes is a sensitive index of compromised cell ATP homeostasis
    • Petrie, J.L., Patman, G.L., Sinha, I., Alexander, T.D., Reeves, H.L., Agius, L. The rate of production of uric acid by hepatocytes is a sensitive index of compromised cell ATP homeostasis. Am. J. Physiol. Endocrinol. Metab. 2013, 305, E1255-E1265.
    • (2013) Am. J. Physiol. Endocrinol. Metab , vol.305 , pp. E1255-E1265
    • Petrie, J.L.1    Patman, G.L.2    Sinha, I.3    Alexander, T.D.4    Reeves, H.L.5    Agius, L.6
  • 85
    • 0014197037 scopus 로고
    • Fructose-induced hyperuricaemia
    • Perheentupa, J., Raivio, K. Fructose-induced hyperuricaemia. Lancet 1967, 2, 528-531.
    • (1967) Lancet , vol.2 , pp. 528-531
    • Perheentupa, J.1    Raivio, K.2
  • 87
    • 0020690698 scopus 로고
    • Serum uric acid, inorganic phosphorus, and glutamic-oxalacetic transaminase and blood pressure in carbohydrate-sensitive adults consuming three different levels of sucrose
    • Israel, K.D., Michaelis, O.E.T., Reiser, S., Keeney, M. Serum uric acid, inorganic phosphorus, and glutamic-oxalacetic transaminase and blood pressure in carbohydrate-sensitive adults consuming three different levels of sucrose. Ann. Nutr. Metab. 1983, 27, 425-435.
    • (1983) Ann. Nutr. Metab , vol.27 , pp. 425-435
    • Israel, K.D.1    Michaelis, O.E.T.2    Reiser, S.3    Keeney, M.4
  • 88
    • 0024372043 scopus 로고
    • Blood lipids, lipoproteins, apoproteins, and uric acid in men fed diets containing fructose or high-amylose cornstarch
    • Reiser, S., Powell, A.S., Scholfield, D.J., Panda, P., Ellwood, K.C., Canary, J.J. Blood lipids, lipoproteins, apoproteins, and uric acid in men fed diets containing fructose or high-amylose cornstarch. Am. J. Clin. Nutr. 1989, 49, 832-839.
    • (1989) Am. J. Clin. Nutr , vol.49 , pp. 832-839
    • Reiser, S.1    Powell, A.S.2    Scholfield, D.J.3    Panda, P.4    Ellwood, K.C.5    Canary, J.J.6
  • 89
    • 80055099872 scopus 로고    scopus 로고
    • TheWestern-style diet: A major risk factor for impaired kidney function and chronic kidney disease
    • Odermatt, A. TheWestern-style diet: A major risk factor for impaired kidney function and chronic kidney disease. Am. J. Physiol. Renal. Physiol. 2011, 301, F919-F931.
    • (2011) Am. J. Physiol. Renal. Physiol , vol.301 , pp. F919-F931
    • Odermatt, A.1
  • 90
    • 33745144316 scopus 로고    scopus 로고
    • Uric acid is a risk factor for myocardial infarction and stroke: The Rotterdam study
    • Bos, M.J., Koudstaal, P.J., Hofman, A., Witteman, J.C., Breteler, M.M. Uric acid is a risk factor for myocardial infarction and stroke: The Rotterdam study. Stroke 2006, 37, 1503-1507.
    • (2006) Stroke , vol.37 , pp. 1503-1507
    • Bos, M.J.1    Koudstaal, P.J.2    Hofman, A.3    Witteman, J.C.4    Breteler, M.M.5
  • 93
    • 34547733397 scopus 로고    scopus 로고
    • Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress
    • Sautin, Y.Y., Nakagawa, T., Zharikov, S., Johnson, R.J. Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress. Am. J. Physiol. Cell Physiol. 2007, 293, C584-C596.
    • (2007) Am. J. Physiol. Cell Physiol , vol.293 , pp. C584-C596
    • Sautin, Y.Y.1    Nakagawa, T.2    Zharikov, S.3    Johnson, R.J.4
  • 95
    • 0017280443 scopus 로고
    • Effect of fructose administration on serum urate levels in the uricase inhibited rat
    • Stavric, B., Johnson, W.J., Clayman, S., Gadd, R.E., Chartrand, A. Effect of fructose administration on serum urate levels in the uricase inhibited rat. Experientia 1976, 32, 373-374.
    • (1976) Experientia , vol.32 , pp. 373-374
    • Stavric, B.1    Johnson, W.J.2    Clayman, S.3    Gadd, R.E.4    Chartrand, A.5
  • 97
    • 0036892724 scopus 로고    scopus 로고
    • Dietary vitamin E and C supplementation prevents fructose induced hypertension in rats
    • Vasdev, S., Gill, V., Parai, S., Longerich, L., Gadag, V. Dietary vitamin E and C supplementation prevents fructose induced hypertension in rats. Mol. Cell Biochem. 2002, 241, 107-114.
    • (2002) Mol. Cell Biochem , vol.241 , pp. 107-114
    • Vasdev, S.1    Gill, V.2    Parai, S.3    Longerich, L.4    Gadag, V.5
  • 98
    • 0038579374 scopus 로고    scopus 로고
    • Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2
    • Kanellis, J., Watanabe, S., Li, J.H., Kang, D.H., Li, P., Nakagawa, T., Wamsley, A., Sheikh-Hamad, D., Lan, H.Y., Feng, L., et al. Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2. Hypertension 2003, 41, 1287-1293.
    • (2003) Hypertension , vol.41 , pp. 1287-1293
    • Kanellis, J.1    Watanabe, S.2    Li, J.H.3    Kang, D.H.4    Li, P.5    Nakagawa, T.6    Wamsley, A.7    Sheikh-Hamad, D.8    Lan, H.Y.9    Feng, L.10
  • 99
    • 34548419344 scopus 로고    scopus 로고
    • Thematic review series: Adipocyte Biology. Adipocyte stress: The endoplasmic reticulum and metabolic disease
    • Gregor, M.F., Hotamisligil, G.S. Thematic review series: Adipocyte Biology. Adipocyte stress: The endoplasmic reticulum and metabolic disease. J. Lipid. Res. 2007, 48, 1905-1914.
    • (2007) J. Lipid. Res , vol.48 , pp. 1905-1914
    • Gregor, M.F.1    Hotamisligil, G.S.2
  • 100
    • 33845325476 scopus 로고    scopus 로고
    • Adipocyte differentiation from the inside out. Nat
    • Rosen, E.D., MacDougald, O.A. Adipocyte differentiation from the inside out. Nat. Rev. Mol. Cell Biol. 2006, 7, 885-896.
    • (2006) Rev. Mol. Cell Biol , vol.7 , pp. 885-896
    • Rosen, E.D.1    Macdougald, O.A.2
  • 101
    • 84921908127 scopus 로고    scopus 로고
    • Adiponectin resistance and proinflammatory changes in the visceral adipose tissue induced by fructose consumption via ketohexokinase-dependent pathway
    • Marek, G., Pannu, V., Shanmugham, P., Pancione, B., Mascia, D., Crosson, S., Ishimoto, T., Sautin, Y.Y. Adiponectin resistance and proinflammatory changes in the visceral adipose tissue induced by fructose consumption via ketohexokinase-dependent pathway. Diabetes 2015, 64, 508-518.
    • (2015) Diabetes , vol.64 , pp. 508-518
    • Marek, G.1    Pannu, V.2    Shanmugham, P.3    Pancione, B.4    Mascia, D.5    Crosson, S.6    Ishimoto, T.7    Sautin, Y.Y.8
  • 102
    • 34248197560 scopus 로고    scopus 로고
    • Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention
    • Wang, Z.V., Schraw, T.D., Kim, J.Y., Khan, T., Rajala, M.W., Follenzi, A., Scherer, P.E. Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention. Mol. Cell Biol. 2007, 27, 3716-3731.
    • (2007) Mol. Cell Biol , vol.27 , pp. 3716-3731
    • Wang, Z.V.1    Schraw, T.D.2    Kim, J.Y.3    Khan, T.4    Rajala, M.W.5    Follenzi, A.6    Scherer, P.E.7
  • 105
    • 75149118560 scopus 로고    scopus 로고
    • The balance between gluco—And mineralo-corticoid action critically determines inflammatory adipocyte responses
    • Hoppmann, J., Perwitz, N., Meier, B., Fasshauer, M., Hadaschik, D., Lehnert, H., Klein, J. The balance between gluco—And mineralo-corticoid action critically determines inflammatory adipocyte responses. J. Endocrinol. 2010, 204, 153-164.
    • (2010) J. Endocrinol , vol.204 , pp. 153-164
    • Hoppmann, J.1    Perwitz, N.2    Meier, B.3    Fasshauer, M.4    Hadaschik, D.5    Lehnert, H.6    Klein, J.7
  • 106
    • 38449115958 scopus 로고    scopus 로고
    • Macrophages from 11beta-hydroxysteroid dehydrogenase type 1-deficient mice exhibit an increased sensitivity to lipopolysaccharide stimulation due to TGF-beta-mediated up-regulation of SHIP1 expression
    • Zhang, T.Y., Daynes, R.A. Macrophages from 11beta-hydroxysteroid dehydrogenase type 1-deficient mice exhibit an increased sensitivity to lipopolysaccharide stimulation due to TGF-beta-mediated up-regulation of SHIP1 expression. J. Immunol. 2007, 179, 6325-6335.
    • (2007) J. Immunol , vol.179 , pp. 6325-6335
    • Zhang, T.Y.1    Daynes, R.A.2
  • 107
    • 84863628857 scopus 로고    scopus 로고
    • BVT.2733, a Selective 11 beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Attenuates Obesity and Inflammation in Diet-Induced Obese Mice
    • Wang, L., Liu, J., Zhang, A.S., Cheng, P., Zhang, X., Lv, S., Wu, L., Yu, J., Di, W.J., Zha, J.M., et al. BVT.2733, a Selective 11 beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Attenuates Obesity and Inflammation in Diet-Induced Obese Mice. PLoS ONE 2012, 7.
    • (2012) Plos ONE , pp. 7
    • Wang, L.1    Liu, J.2    Zhang, A.S.3    Cheng, P.4    Zhang, X.5    Lv, S.6    Wu, L.7    Yu, J.8    Di, W.J.9    Zha, J.M.10
  • 108
    • 84994499327 scopus 로고    scopus 로고
    • Anti-inflammatory effect of a selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor via the stimulation of heme oxygenase-1 in LPS-activated mice and J774.1 murine macrophages
    • Park, S.B., Park, J.S., Jung, W.H., Kim, H.Y., Kwak, H.J., Ahn, J.H., Choi, K.J., Na, Y.J., Choi, S., Rhee, S.D., et al. Anti-inflammatory effect of a selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor via the stimulation of heme oxygenase-1 in LPS-activated mice and J774.1 murine macrophages. J. Pharmacol. Sci. 2016, 131, 241-250.
    • (2016) J. Pharmacol. Sci. , vol.131 , pp. 241-250
    • Park, S.B.1    Park, J.S.2    Jung, W.H.3    Kim, H.Y.4    Kwak, H.J.5    Ahn, J.H.6    Choi, K.J.7    Na, Y.J.8    Choi, S.9    Rhee, S.D.10
  • 110
    • 84870057420 scopus 로고    scopus 로고
    • Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells
    • Chantong, B., Kratschmar, D.V., Nashev, L.G., Balazs, Z., Odermatt, A. Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells. J. Neuroinflamm. 2012, 9, 260.
    • (2012) J. Neuroinflamm , vol.9 , pp. 260
    • Chantong, B.1    Kratschmar, D.V.2    Nashev, L.G.3    Balazs, Z.4    Odermatt, A.5
  • 113
    • 79955446251 scopus 로고    scopus 로고
    • Nonalcoholic Steatohepatitis Clinical Research, Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: The TONIC randomized controlled trial
    • Lavine, J.E., Schwimmer, J.B., van Natta, M.L., Molleston, J.P., Murray, K.F., Rosenthal, P., Abrams, S.H., Scheimann, A.O., Sanyal, A.J., Chalasani, N., et al. Nonalcoholic Steatohepatitis Clinical Research, Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: The TONIC randomized controlled trial. JAMA 2011, 305, 1659-1668.
    • (2011) JAMA , vol.305 , pp. 1659-1668
    • Lavine, J.E.1    Schwimmer, J.B.2    Van Natta, M.L.3    Molleston, J.P.4    Murray, K.F.5    Rosenthal, P.6    Abrams, S.H.7    Scheimann, A.O.8    Sanyal, A.J.9    Chalasani, N.10
  • 115
    • 0030936556 scopus 로고    scopus 로고
    • Does central obesity reflect ”Cushing’s disease of the omentum”?
    • Bujalska, I.J., Kumar, S., Stewart, P.M. Does central obesity reflect ”Cushing’s disease of the omentum”? Lancet 1997, 349, 1210-1213.
    • (1997) Lancet , vol.349 , pp. 1210-1213
    • Bujalska, I.J.1    Kumar, S.2    Stewart, P.M.3
  • 116
    • 0141739647 scopus 로고    scopus 로고
    • Tissue-specific Cushing’s syndrome, 11beta-hydroxysteroid dehydrogenases and the redefinition of corticosteroid hormone action
    • Stewart, P.M. Tissue-specific Cushing’s syndrome, 11beta-hydroxysteroid dehydrogenases and the redefinition of corticosteroid hormone action. Eur. J. Endocrinol. 2003, 149, 163-168.
    • (2003) Eur. J. Endocrinol , vol.149 , pp. 163-168
    • Stewart, P.M.1
  • 117
    • 84888819674 scopus 로고    scopus 로고
    • Daily profile in two circadian markers ”melatonin and cortisol” and associations with metabolic syndrome components
    • Corbalan-Tutau, D., Madrid, J.A., Nicolas, F., Garaulet, M. Daily profile in two circadian markers ”melatonin and cortisol” and associations with metabolic syndrome components. Physiol. Behav. 2014, 123, 231-235.
    • (2014) Physiol. Behav , vol.123 , pp. 231-235
    • Corbalan-Tutau, D.1    Madrid, J.A.2    Nicolas, F.3    Garaulet, M.4
  • 118
    • 84874935964 scopus 로고    scopus 로고
    • An accurate, non-invasive approach to diagnose Cushing’s syndrome in at-risk populations
    • Cardoso, E.M., Arregger, A.L., Monardes, G., Contreras, L.N. An accurate, non-invasive approach to diagnose Cushing’s syndrome in at-risk populations. Steroids 2013, 78, 476-482.
    • (2013) Steroids , vol.78 , pp. 476-482
    • Cardoso, E.M.1    Arregger, A.L.2    Monardes, G.3    Contreras, L.N.4
  • 119
    • 84904061725 scopus 로고    scopus 로고
    • Relationships between 24-hour urinary free cortisol concentrations and metabolic syndrome in obese children
    • Reinehr, T., Kulle, A., Wolters, B., Knop, C., Lass, N., Welzel, M., Holterhus, P.M. Relationships between 24-hour urinary free cortisol concentrations and metabolic syndrome in obese children. J. Clin. Endocrinol. Metab. 2014, 99, 2391-2399.
    • (2014) J. Clin. Endocrinol. Metab , vol.99 , pp. 2391-2399
    • Reinehr, T.1    Kulle, A.2    Wolters, B.3    Knop, C.4    Lass, N.5    Welzel, M.6    Holterhus, P.M.7
  • 120
    • 0034463972 scopus 로고    scopus 로고
    • Understanding the role of glucocorticoids in obesity: Tissue-specific alterations of corticosterone metabolism in obese Zucker rats
    • Livingstone, D.E., Jones, G.C., Smith, K., Jamieson, P.M., Andrew, R., Kenyon, C.J., Walker, B.R. Understanding the role of glucocorticoids in obesity: Tissue-specific alterations of corticosterone metabolism in obese Zucker rats. Endocrinology 2000, 141, 560-563.
    • (2000) Endocrinology , vol.141 , pp. 560-563
    • Livingstone, D.E.1    Jones, G.C.2    Smith, K.3    Jamieson, P.M.4    Rew, R.5    Kenyon, C.J.6    Walker, B.R.7
  • 122
    • 0036324073 scopus 로고    scopus 로고
    • Tissue-specific changes in peripheral cortisol metabolism in obese women: Increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity
    • Rask, E., Walker, B.R., Soderberg, S., Livingstone, D.E., Eliasson, M., Johnson, O., Andrew, R., Olsson, T. Tissue-specific changes in peripheral cortisol metabolism in obese women: Increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity. J. Clin. Endocrinol. Metab. 2002, 87, 3330-3336.
    • (2002) J. Clin. Endocrinol. Metab , vol.87 , pp. 3330-3336
    • Rask, E.1    Walker, B.R.2    Soderberg, S.3    Livingstone, D.E.4    Eliasson, M.5    Johnson, O.6    Rew, R.7    Olsson, T.8
  • 124
    • 0032990860 scopus 로고    scopus 로고
    • Cortisol metabolism in human obesity: Impaired cortisone!cortisol conversion in subjects with central adiposity
    • Stewart, P.M., Boulton, A., Kumar, S., Clark, P.M., Shackleton, C.H. Cortisol metabolism in human obesity: Impaired cortisone!cortisol conversion in subjects with central adiposity. J. Clin. Endocrinol. Metab. 1999, 84, 1022-1027.
    • (1999) J. Clin. Endocrinol. Metab , vol.84 , pp. 1022-1027
    • Stewart, P.M.1    Boulton, A.2    Kumar, S.3    Clark, P.M.4    Shackleton, C.H.5
  • 125
    • 10744221420 scopus 로고    scopus 로고
    • Body fat distribution and cortisol metabolism in healthy men: Enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver
    • Westerbacka, J., Yki-Jarvinen, H., Vehkavaara, S., Hakkinen, A.M., Andrew, R., Wake, D.J., Seckl, J.R., Walker, B.R. Body fat distribution and cortisol metabolism in healthy men: Enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver. J. Clin. Endocrinol. Metab. 2003, 88, 4924-4931.
    • (2003) J. Clin. Endocrinol. Metab , vol.88 , pp. 4924-4931
    • Westerbacka, J.1    Yki-Jarvinen, H.2    Vehkavaara, S.3    Hakkinen, A.M.4    Rew, R.5    Wake, D.J.6    Seckl, J.R.7    Walker, B.R.8
  • 129
    • 0024440502 scopus 로고
    • Promoting effect of glucocorticoids on the differentiation of human adipocyte precursor cells cultured in a chemically defined medium
    • Hauner, H., Entenmann, G., Wabitsch, M., Gaillard, D., Ailhaud, G., Negrel, R., Pfeiffer, E.F. Promoting effect of glucocorticoids on the differentiation of human adipocyte precursor cells cultured in a chemically defined medium. J. Clin. Investig. 1989, 84, 1663-1670.
    • (1989) J. Clin. Investig , vol.84 , pp. 1663-1670
    • Hauner, H.1    Entenmann, G.2    Wabitsch, M.3    Gaillard, D.4    Ailhaud, G.5    Negrel, R.6    Pfeiffer, E.F.7
  • 130
    • 0023109747 scopus 로고
    • Glucocorticoids and insulin promote the differentiation of human adipocyte precursor cells into fat cells
    • Hauner, H., Schmid, P., Pfeiffer, E.F. Glucocorticoids and insulin promote the differentiation of human adipocyte precursor cells into fat cells. J. Clin. Endocrinol. Metab. 1987, 64, 832-835.
    • (1987) J. Clin. Endocrinol. Metab , vol.64 , pp. 832-835
    • Hauner, H.1    Schmid, P.2    Pfeiffer, E.F.3
  • 131
    • 0036875204 scopus 로고    scopus 로고
    • The functional consequences of 11beta-hydroxysteroid dehydrogenase expression in adipose tissue
    • Tomlinson, J.W., Stewart, P.M. The functional consequences of 11beta-hydroxysteroid dehydrogenase expression in adipose tissue. Horm. Metab. Res. 2002, 34, 746-751.
    • (2002) Horm. Metab. Res , vol.34 , pp. 746-751
    • Tomlinson, J.W.1    Stewart, P.M.2
  • 132
    • 0033305631 scopus 로고    scopus 로고
    • Differentiation of adipose stromal cells: The roles of glucocorticoids and 11beta-hydroxysteroid dehydrogenase
    • Bujalska, I.J., Kumar, S., Hewison, M., Stewart, P.M. Differentiation of adipose stromal cells: The roles of glucocorticoids and 11beta-hydroxysteroid dehydrogenase. Endocrinology 1999, 140, 3188-3196.
    • (1999) Endocrinology , vol.140 , pp. 3188-3196
    • Bujalska, I.J.1    Kumar, S.2    Hewison, M.3    Stewart, P.M.4
  • 133
    • 40149097328 scopus 로고    scopus 로고
    • Suppression of 11beta-hydroxysteroid dehydrogenase type 1 with RNA interference substantially attenuates 3T3-L1 adipogenesis
    • Liu, Y., Park, F., Pietrusz, J.L., Jia, G., Singh, R.J., Netzel, B.C., Liang, M. Suppression of 11beta-hydroxysteroid dehydrogenase type 1 with RNA interference substantially attenuates 3T3-L1 adipogenesis. Physiol. Genom. 2008, 32, 343-351.
    • (2008) Physiol. Genom , vol.32 , pp. 343-351
    • Liu, Y.1    Park, F.2    Pietrusz, J.L.3    Jia, G.4    Singh, R.J.5    Netzel, B.C.6    Liang, M.7
  • 135
    • 60249093534 scopus 로고    scopus 로고
    • 11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose
    • Dzyakanchuk, A.A., Balazs, Z., Nashev, L.G., Amrein, K.E., Odermatt, A. 11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose. Mol. Cell Endocrinol. 2009, 301, 137-141.
    • (2009) Mol. Cell Endocrinol , vol.301 , pp. 137-141
    • Dzyakanchuk, A.A.1    Balazs, Z.2    Nashev, L.G.3    Amrein, K.E.4    Odermatt, A.5
  • 137
    • 0007519956 scopus 로고
    • Fructose metabolism of adipose tissue. I. Comparison of fructose and glucose metabolism in epididymal adipose tissue of normal rats
    • Froesch, E.R., Ginsberg, J.L. Fructose metabolism of adipose tissue. I. Comparison of fructose and glucose metabolism in epididymal adipose tissue of normal rats. J. Biol. Chem. 1962, 237, 3317-3324.
    • (1962) J. Biol. Chem. , vol.237 , pp. 3317-3324
    • Froesch, E.R.1    Ginsberg, J.L.2
  • 141
    • 85028665669 scopus 로고    scopus 로고
    • Fructose and stress induce opposite effects on lipid metabolism in the visceral adipose tissue of adult female rats through glucocorticoid action
    • Kovacevic, S., Nestorov, J., Matic, G., Elakovic, I. Fructose and stress induce opposite effects on lipid metabolism in the visceral adipose tissue of adult female rats through glucocorticoid action. Europ. J. Nutr. 2016.
    • (2016) Europ. J. Nutr
    • Kovacevic, S.1    Nestorov, J.2    Matic, G.3    Elakovic, I.4
  • 144
    • 84995532199 scopus 로고    scopus 로고
    • Glucocorticoid Antagonism Reduces Insulin Resistance and Associated Lipid Abnormalities in High-Fructose-Fed Mice
    • Priyadarshini, E., Anuradha, C.V. Glucocorticoid Antagonism Reduces Insulin Resistance and Associated Lipid Abnormalities in High-Fructose-Fed Mice. Can. J. Diabet. 2017, 41, 41-51.
    • (2017) Can. J. Diabet , vol.41 , pp. 41-51
    • Priyadarshini, E.1    Anuradha, C.V.2
  • 146
    • 0032965030 scopus 로고    scopus 로고
    • De novo lipogenesis in humans: Metabolic and regulatory aspects
    • Hellerstein, M.K. De novo lipogenesis in humans: Metabolic and regulatory aspects. Eur. J. Clin. Nutr. 1999, 53, S53-S65.
    • (1999) Eur. J. Clin. Nutr , vol.53 , pp. S53-S65
    • Hellerstein, M.K.1
  • 147
    • 0015432606 scopus 로고
    • Tissue effects of glucocorticoids
    • Baxter, J.D., Forsham, P.H. Tissue effects of glucocorticoids. Am. J. Med. 1972, 53, 573-589.
    • (1972) Am. J. Med , vol.53 , pp. 573-589
    • Baxter, J.D.1    Forsham, P.H.2
  • 148
    • 1642545652 scopus 로고    scopus 로고
    • Regulation of the enzymes of hepatic microsomal triacylglycerol lipolysis and re-esterification by the glucocorticoid dexamethasone
    • Dolinsky, V.W., Douglas, D.N., Lehner, R., Vance, D.E. Regulation of the enzymes of hepatic microsomal triacylglycerol lipolysis and re-esterification by the glucocorticoid dexamethasone. Biochem. J. 2004, 378, 967-974.
    • (2004) Biochem. J. , vol.378 , pp. 967-974
    • Dolinsky, V.W.1    Douglas, D.N.2    Lehner, R.3    Vance, D.E.4


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