메뉴 건너뛰기




Volumn 11, Issue 12, 2017, Pages 3457-3468

MicroRNAs can effectively induce formation of insulin-producing cells from mesenchymal stem cells

Author keywords

insulin secretion; insulin producing cells; mesenchymal stem cells; microRNAs; small interfering RNAs

Indexed keywords

COPYRIGHTS; GENE EXPRESSION; INSULIN; PHYSIOLOGY; RNA; STEM CELLS;

EID: 85017585597     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.2259     Document Type: Article
Times cited : (32)

References (57)
  • 1
    • 84934293109 scopus 로고    scopus 로고
    • Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3beta pathway in the mouse hippocampus
    • Ali T, Kim MO. 2015; Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3beta pathway in the mouse hippocampus. J Pineal Res 59: 47–59.
    • (2015) J Pineal Res , vol.59 , pp. 47-59
    • Ali, T.1    Kim, M.O.2
  • 2
    • 84938423623 scopus 로고    scopus 로고
    • Functions of melatonin in plants: a review
    • Arnao MB, Hernandez-Ruiz J. 2015; Functions of melatonin in plants: a review. J Pineal Res 59: 133–150.
    • (2015) J Pineal Res , vol.59 , pp. 133-150
    • Arnao, M.B.1    Hernandez-Ruiz, J.2
  • 3
    • 64549163250 scopus 로고    scopus 로고
    • The promoter of the pri-miR-375 gene directs expression selectively to the endocrine pancreas
    • Avnit-Sagi T, Kantorovich L, Kredo-Russo S, Hornstein E, Walker MD. 2009; The promoter of the pri-miR-375 gene directs expression selectively to the endocrine pancreas. PLoS One 4: e5033.
    • (2009) PLoS One , vol.4
    • Avnit-Sagi, T.1    Kantorovich, L.2    Kredo-Russo, S.3    Hornstein, E.4    Walker, M.D.5
  • 4
    • 84949676457 scopus 로고    scopus 로고
    • Role of microRNA-21 in the formation of insulin-producing cells from pancreatic progenitor cells
    • Bai C, Li X, Gao Y et al. 2015; Role of microRNA-21 in the formation of insulin-producing cells from pancreatic progenitor cells. Biochim Biophys Acta 1859: 280–293.
    • (2015) Biochim Biophys Acta , vol.1859 , pp. 280-293
    • Bai, C.1    Li, X.2    Gao, Y.3
  • 5
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel DP. 2004; MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281–297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 6
    • 84899453869 scopus 로고    scopus 로고
    • Calcium-signaling components in rat insulinoma beta-cells (INS-1) and pancreatic islets are differentially influenced by melatonin
    • Bazwinsky-Wutschke I, Muhlbauer E, Albrecht E, Peschke E. 2014; Calcium-signaling components in rat insulinoma beta-cells (INS-1) and pancreatic islets are differentially influenced by melatonin. J Pineal Res 56: 439–449.
    • (2014) J Pineal Res , vol.56 , pp. 439-449
    • Bazwinsky-Wutschke, I.1    Muhlbauer, E.2    Albrecht, E.3    Peschke, E.4
  • 7
    • 53649097239 scopus 로고    scopus 로고
    • Pancreatic transcription factors and their role in the birth, life and survival of the pancreatic beta cell
    • Bernardo AS, Hay CW, Docherty K. 2008; Pancreatic transcription factors and their role in the birth, life and survival of the pancreatic beta cell. Mol Cell Endocrinol 294: 1–9.
    • (2008) Mol Cell Endocrinol , vol.294 , pp. 1-9
    • Bernardo, A.S.1    Hay, C.W.2    Docherty, K.3
  • 8
    • 0037306116 scopus 로고    scopus 로고
    • The chicken as a model for large-scale analysis of vertebrate gene function
    • Brown WR, Hubbard SJ, Tickle C, Wilson SA. 2003; The chicken as a model for large-scale analysis of vertebrate gene function. Nat Rev Genet 4: 87–98.
    • (2003) Nat Rev Genet , vol.4 , pp. 87-98
    • Brown, W.R.1    Hubbard, S.J.2    Tickle, C.3    Wilson, S.A.4
  • 9
    • 84936853416 scopus 로고    scopus 로고
    • MicroRNA-196b is transcribed from an autonomous promoter and is directly regulated by Cdx2 and by posterior Hox proteins during embryogenesis
    • Fantini S, Salsi V, Vitobello A, Rijli FM, Zappavigna V. 2015; MicroRNA-196b is transcribed from an autonomous promoter and is directly regulated by Cdx2 and by posterior Hox proteins during embryogenesis. Biochim Biophys Acta 1849: 1066–1080.
    • (2015) Biochim Biophys Acta , vol.1849 , pp. 1066-1080
    • Fantini, S.1    Salsi, V.2    Vitobello, A.3    Rijli, F.M.4    Zappavigna, V.5
  • 10
    • 84924717555 scopus 로고    scopus 로고
    • Pinealectomy interferes with the circadian clock genes expression in white adipose tissue
    • de Farias Tda S, de Oliveira AC, Andreotti S et al. 2015; Pinealectomy interferes with the circadian clock genes expression in white adipose tissue. J Pineal Res 58: 251–261.
    • (2015) J Pineal Res , vol.58 , pp. 251-261
    • de Farias Tda, S.1    de Oliveira, A.C.2    Andreotti, S.3
  • 11
    • 84887046365 scopus 로고    scopus 로고
    • MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation
    • Fu X, Jin L, Wang X et al. 2013; MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation. Proc Natl Acad Sci USA 110: 17 892–17 897.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 17 892-17 897
    • Fu, X.1    Jin, L.2    Wang, X.3
  • 12
    • 0026016780 scopus 로고
    • Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer
    • German MS, Blanar MA, Nelson C, Moss LG, Rutter WJ. 1991; Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer. Mol Endocrinol 5: 292–299.
    • (1991) Mol Endocrinol , vol.5 , pp. 292-299
    • German, M.S.1    Blanar, M.A.2    Nelson, C.3    Moss, L.G.4    Rutter, W.J.5
  • 13
    • 0038036797 scopus 로고    scopus 로고
    • Rapamycin inhibits IL-4-induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo
    • Hackstein H, Taner T, Zahorchak AF et al. 2003; Rapamycin inhibits IL-4-induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo. Blood 101: 4457–4463.
    • (2003) Blood , vol.101 , pp. 4457-4463
    • Hackstein, H.1    Taner, T.2    Zahorchak, A.F.3
  • 15
    • 0034728764 scopus 로고    scopus 로고
    • Nestin-expressing cells in the pancreatic islets of Langerhans
    • Hunziker E, Stein M. 2000; Nestin-expressing cells in the pancreatic islets of Langerhans. Biochem Biophys Res Commun 271: 116–119.
    • (2000) Biochem Biophys Res Commun , vol.271 , pp. 116-119
    • Hunziker, E.1    Stein, M.2
  • 16
    • 27844499690 scopus 로고    scopus 로고
    • SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice
    • Iguchi H, Ikeda Y, Okamura M et al. 2005; SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice. J Biol Chem 280: 37 669–37 680.
    • (2005) J Biol Chem , pp. 37 669-37 680
    • Iguchi, H.1    Ikeda, Y.2    Okamura, M.3
  • 17
    • 34547129844 scopus 로고    scopus 로고
    • SOX6 suppresses cyclin D1 promoter activity by interacting with beta-catenin and histone deacetylase 1, and its down-regulation induces pancreatic beta-cell proliferation
    • Iguchi H, Urashima Y, Inagaki Y et al. 2007; SOX6 suppresses cyclin D1 promoter activity by interacting with beta-catenin and histone deacetylase 1, and its down-regulation induces pancreatic beta-cell proliferation. J Biol Chem 282: 19 052–19 061.
    • (2007) J Biol Chem , vol.282 , pp. 19 052-19 061
    • Iguchi, H.1    Urashima, Y.2    Inagaki, Y.3
  • 18
    • 84955197589 scopus 로고    scopus 로고
    • Melatonin rescues cardiovascular dysfunction during hypoxic development in the chick embryo
    • Itani N, Skeffington KL, Beck C, Niu Y, Giussani DA. 2016; Melatonin rescues cardiovascular dysfunction during hypoxic development in the chick embryo. J Pineal Res 60: 16–26.
    • (2016) J Pineal Res , vol.60 , pp. 16-26
    • Itani, N.1    Skeffington, K.L.2    Beck, C.3    Niu, Y.4    Giussani, D.A.5
  • 19
    • 84455161954 scopus 로고    scopus 로고
    • Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus
    • Kalis M, Bolmeson C, Esguerra JL et al. 2011; Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus. PLoS One 6: e29166.
    • (2011) PLoS One , vol.6
    • Kalis, M.1    Bolmeson, C.2    Esguerra, J.L.3
  • 20
    • 20944450160 scopus 로고    scopus 로고
    • Combinatorial microRNA target predictions
    • Krek A, Grun D, Poy MN et al. 2005; Combinatorial microRNA target predictions. Nat Genet 37: 495–500.
    • (2005) Nat Genet , vol.37 , pp. 495-500
    • Krek, A.1    Grun, D.2    Poy, M.N.3
  • 21
    • 17644387563 scopus 로고    scopus 로고
    • Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth
    • Kushner JA, Ciemerych MA, Sicinska E et al. 2005; Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth. Mol Cell Biol 25: 3752–3762.
    • (2005) Mol Cell Biol , vol.25 , pp. 3752-3762
    • Kushner, J.A.1    Ciemerych, M.A.2    Sicinska, E.3
  • 22
    • 0036246856 scopus 로고    scopus 로고
    • Pdx1 restores beta cell function in Irs2 knockout mice
    • Kushner JA, Ye J, Schubert M et al. 2002; Pdx1 restores beta cell function in Irs2 knockout mice. J Clin Invest 109: 1193–1201.
    • (2002) J Clin Invest , vol.109 , pp. 1193-1201
    • Kushner, J.A.1    Ye, J.2    Schubert, M.3
  • 23
    • 84897499406 scopus 로고    scopus 로고
    • MiRNA-375 promotes beta pancreatic differentiation in human induced pluripotent stem (hiPS) cells
    • Lahmy R, Soleimani M, Sanati MH, Behmanesh M, Kouhkan F, Mobarra N. 2014; MiRNA-375 promotes beta pancreatic differentiation in human induced pluripotent stem (hiPS) cells. Mol Biol Rep 41: 2055–2066.
    • (2014) Mol Biol Rep , vol.41 , pp. 2055-2066
    • Lahmy, R.1    Soleimani, M.2    Sanati, M.H.3    Behmanesh, M.4    Kouhkan, F.5    Mobarra, N.6
  • 24
    • 0036082806 scopus 로고    scopus 로고
    • Nestin expression in pancreatic stellate cells and angiogenic endothelial cells
    • Lardon J, Rooman I, Bouwens L. 2002; Nestin expression in pancreatic stellate cells and angiogenic endothelial cells. Histochem Cell Biol 117: 535–540.
    • (2002) Histochem Cell Biol , vol.117 , pp. 535-540
    • Lardon, J.1    Rooman, I.2    Bouwens, L.3
  • 25
    • 40149083894 scopus 로고    scopus 로고
    • Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs
    • Lovis P, Gattesco S, Regazzi R. 2008; Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs. Biol Chem 389: 305–312.
    • (2008) Biol Chem , vol.389 , pp. 305-312
    • Lovis, P.1    Gattesco, S.2    Regazzi, R.3
  • 26
    • 79952259862 scopus 로고    scopus 로고
    • miRNAs control insulin content in pancreatic beta-cells via downregulation of transcriptional repressors
    • Melkman-Zehavi T, Oren R, Kredo-Russo S et al. 2011; miRNAs control insulin content in pancreatic beta-cells via downregulation of transcriptional repressors. EMBO J 30: 835–845.
    • (2011) EMBO J , vol.30 , pp. 835-845
    • Melkman-Zehavi, T.1    Oren, R.2    Kredo-Russo, S.3
  • 27
    • 79955528254 scopus 로고    scopus 로고
    • Differentiation of nestin-positive cells derived from bone marrow into pancreatic endocrine and ductal cells in vitro
    • Milanesi A, Lee JW, Xu Q, Perin L, Yu JS. 2011; Differentiation of nestin-positive cells derived from bone marrow into pancreatic endocrine and ductal cells in vitro. J Endocrinol 209: 193–201.
    • (2011) J Endocrinol , vol.209 , pp. 193-201
    • Milanesi, A.1    Lee, J.W.2    Xu, Q.3    Perin, L.4    Yu, J.S.5
  • 28
    • 84921927758 scopus 로고    scopus 로고
    • Regulation of skeletal muscle development and homeostasis by gene imprinting, histone acetylation and microRNA
    • Moresi V, Marroncelli N, Coletti D, Adamo S. 2015; Regulation of skeletal muscle development and homeostasis by gene imprinting, histone acetylation and microRNA. Biochim Biophys Acta 1849: 309–316.
    • (2015) Biochim Biophys Acta , vol.1849 , pp. 309-316
    • Moresi, V.1    Marroncelli, N.2    Coletti, D.3    Adamo, S.4
  • 29
    • 84865958164 scopus 로고    scopus 로고
    • miR-142-3p is essential for hematopoiesis and affects cardiac cell fate in zebrafish
    • Nishiyama T, Kaneda R, Ono T et al. 2012; miR-142-3p is essential for hematopoiesis and affects cardiac cell fate in zebrafish. Biochem Biophys Res Commun 425: 755–761.
    • (2012) Biochem Biophys Res Commun , vol.425 , pp. 755-761
    • Nishiyama, T.1    Kaneda, R.2    Ono, T.3
  • 30
    • 0023872502 scopus 로고
    • Maturation of insulin response to glucose during human fetal and neonatal development. Studies with perifusion of pancreatic isletlike cell clusters
    • Otonkoski T, Andersson S, Knip M, Simell O. 1988; Maturation of insulin response to glucose during human fetal and neonatal development. Studies with perifusion of pancreatic isletlike cell clusters. Diabetes 37: 286–291.
    • (1988) Diabetes , vol.37 , pp. 286-291
    • Otonkoski, T.1    Andersson, S.2    Knip, M.3    Simell, O.4
  • 31
    • 0027265403 scopus 로고
    • Nicotinamide is a potent inducer of endocrine differentiation in cultured human fetal pancreatic cells
    • Otonkoski T, Beattie GM, Mally MI, Ricordi C, Hayek A. 1993; Nicotinamide is a potent inducer of endocrine differentiation in cultured human fetal pancreatic cells. J Clin Invest 92: 1459–1466.
    • (1993) J Clin Invest , vol.92 , pp. 1459-1466
    • Otonkoski, T.1    Beattie, G.M.2    Mally, M.I.3    Ricordi, C.4    Hayek, A.5
  • 32
    • 84910673362 scopus 로고    scopus 로고
    • Generation of functional human pancreatic beta cells in vitro
    • Pagliuca FW, Millman JR, Gurtler M et al. 2014; Generation of functional human pancreatic beta cells in vitro. Cell 159: 428–439.
    • (2014) Cell , vol.159 , pp. 428-439
    • Pagliuca, F.W.1    Millman, J.R.2    Gurtler, M.3
  • 33
    • 0028567837 scopus 로고
    • Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1
    • Peers B, Leonard J, Sharma S, Teitelman G, Montminy MR. 1994; Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1. Mol Endocrinol 8: 1798–1806.
    • (1994) Mol Endocrinol , vol.8 , pp. 1798-1806
    • Peers, B.1    Leonard, J.2    Sharma, S.3    Teitelman, G.4    Montminy, M.R.5
  • 34
    • 84878432544 scopus 로고    scopus 로고
    • Brief demethylation step allows the conversion of adult human skin fibroblasts into insulin-secreting cells
    • Pennarossa G, Maffei S, Campagnol M, Tarantini L, Gandolfi F, Brevini TA. 2013; Brief demethylation step allows the conversion of adult human skin fibroblasts into insulin-secreting cells. Proc Natl Acad Sci USA 110: 8948–8953.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 8948-8953
    • Pennarossa, G.1    Maffei, S.2    Campagnol, M.3    Tarantini, L.4    Gandolfi, F.5    Brevini, T.A.6
  • 35
    • 0034530947 scopus 로고    scopus 로고
    • The PDX-1 activation domain provides specific functions necessary for transcriptional stimulation in pancreatic beta-cells
    • Peshavaria M, Cissell MA, Henderson E, Petersen HV, Stein R. 2000; The PDX-1 activation domain provides specific functions necessary for transcriptional stimulation in pancreatic beta-cells. Mol Endocrinol 14: 1907–1917.
    • (2000) Mol Endocrinol , vol.14 , pp. 1907-1917
    • Peshavaria, M.1    Cissell, M.A.2    Henderson, E.3    Petersen, H.V.4    Stein, R.5
  • 36
    • 0032563330 scopus 로고    scopus 로고
    • Glucose stimulates the activation domain potential of the PDX-1 homeodomain transcription factor
    • Petersen HV, Peshavaria M, Pedersen AA et al. 1998; Glucose stimulates the activation domain potential of the PDX-1 homeodomain transcription factor. FEBS Lett 431: 362–366.
    • (1998) FEBS Lett , vol.431 , pp. 362-366
    • Petersen, H.V.1    Peshavaria, M.2    Pedersen, A.A.3
  • 37
    • 0030048769 scopus 로고    scopus 로고
    • BETA3, a novel helix-loop-helix protein, can act as a negative regulator of BETA2 and MyoD-responsive genes
    • Peyton M, Stellrecht CM, Naya FJ, Huang HP, Samora PJ, Tsai MJ. 1996; BETA3, a novel helix-loop-helix protein, can act as a negative regulator of BETA2 and MyoD-responsive genes. Mol Cell Biol 16: 626–633.
    • (1996) Mol Cell Biol , vol.16 , pp. 626-633
    • Peyton, M.1    Stellrecht, C.M.2    Naya, F.J.3    Huang, H.P.4    Samora, P.J.5    Tsai, M.J.6
  • 38
    • 84897003161 scopus 로고    scopus 로고
    • Role of microRNAs in islet beta-cell compensation and failure during diabetes
    • Plaisance V, Waeber G, Regazzi R, Abderrahmani A. 2014; Role of microRNAs in islet beta-cell compensation and failure during diabetes. J Diabetes Res 2014: 618–652.
    • (2014) J Diabetes Res , vol.2014 , pp. 618-652
    • Plaisance, V.1    Waeber, G.2    Regazzi, R.3    Abderrahmani, A.4
  • 39
    • 9144270691 scopus 로고    scopus 로고
    • A pancreatic islet-specific microRNA regulates insulin secretion
    • Poy MN, Eliasson L, Krutzfeldt J et al. 2004; A pancreatic islet-specific microRNA regulates insulin secretion. Nature 432: 226–230.
    • (2004) Nature , vol.432 , pp. 226-230
    • Poy, M.N.1    Eliasson, L.2    Krutzfeldt, J.3
  • 40
    • 65249093130 scopus 로고    scopus 로고
    • miR-375 maintains normal pancreatic alpha- and beta-cell mass
    • Poy MN, Hausser J, Trajkovski M et al. 2009; miR-375 maintains normal pancreatic alpha- and beta-cell mass. Proc Natl Acad Sci USA 106: 5813–5818.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 5813-5818
    • Poy, M.N.1    Hausser, J.2    Trajkovski, M.3
  • 41
    • 77950560584 scopus 로고    scopus 로고
    • MicroRNA-21 is induced early in pancreatic ductal adenocarcinoma precursor lesions
    • du Rieu MC, Torrisani J, Selves J et al. 2010; MicroRNA-21 is induced early in pancreatic ductal adenocarcinoma precursor lesions. Clin Chem 56: 603–612.
    • (2010) Clin Chem , vol.56 , pp. 603-612
    • du Rieu, M.C.1    Torrisani, J.2    Selves, J.3
  • 42
    • 33750600178 scopus 로고    scopus 로고
    • MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior
    • Roldo C, Missiaglia E, Hagan JP et al. 2006; MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J Clin Oncol 24: 4677–4684.
    • (2006) J Clin Oncol , vol.24 , pp. 4677-4684
    • Roldo, C.1    Missiaglia, E.2    Hagan, J.P.3
  • 43
    • 77956863085 scopus 로고    scopus 로고
    • MicroRNA signature of the human developing pancreas
    • Rosero S, Bravo-Egana V, Jiang Z et al. 2010; MicroRNA signature of the human developing pancreas. BMC Genomics 11: 509.
    • (2010) BMC Genomics , vol.11 , pp. 509
    • Rosero, S.1    Bravo-Egana, V.2    Jiang, Z.3
  • 44
    • 0037789540 scopus 로고    scopus 로고
    • Alternative sources of beta cells for cell therapy of diabetes
    • Scharfmann R. 2003; Alternative sources of beta cells for cell therapy of diabetes. Eur J Clin Invest 33: 595–600.
    • (2003) Eur J Clin Invest , vol.33 , pp. 595-600
    • Scharfmann, R.1
  • 45
    • 0036230386 scopus 로고    scopus 로고
    • Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas
    • Selander L, Edlund H. 2002; Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas. Mech Dev 113: 189–192.
    • (2002) Mech Dev , vol.113 , pp. 189-192
    • Selander, L.1    Edlund, H.2
  • 46
    • 0025131865 scopus 로고
    • Myotrophin: purification of a novel peptide from spontaneously hypertensive rat heart that influences myocardial growth
    • Sen S, Kundu G, Mekhail N, Castel J, Misono K, Healy B. 1990; Myotrophin: purification of a novel peptide from spontaneously hypertensive rat heart that influences myocardial growth. J Biol Chem 265: 16 635–16 643.
    • (1990) J Biol Chem , vol.265 , pp. 16 635-16 643
    • Sen, S.1    Kundu, G.2    Mekhail, N.3    Castel, J.4    Misono, K.5    Healy, B.6
  • 47
    • 84907656936 scopus 로고    scopus 로고
    • miR-375 induces human decidua basalis-derived stromal cells to become insulin-producing cells
    • Shaer A, Azarpira N, Vahdati A, Karimi MH, Shariati M. 2014; miR-375 induces human decidua basalis-derived stromal cells to become insulin-producing cells. Cell Mol Biol Lett 19: 483–499.
    • (2014) Cell Mol Biol Lett , vol.19 , pp. 483-499
    • Shaer, A.1    Azarpira, N.2    Vahdati, A.3    Karimi, M.H.4    Shariati, M.5
  • 48
    • 18444407829 scopus 로고    scopus 로고
    • Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid
    • Shi Y, Hou L, Tang F et al. 2005; Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid. Stem Cells 23: 656–662.
    • (2005) Stem Cells , vol.23 , pp. 656-662
    • Shi, Y.1    Hou, L.2    Tang, F.3
  • 49
    • 84855447249 scopus 로고    scopus 로고
    • MicroRNAs: processing, maturation, target recognition and regulatory functions
    • Shukla GC, Singh J, Barik S. 2011; MicroRNAs: processing, maturation, target recognition and regulatory functions. Mol Cell Pharmacol 3: 83–92.
    • (2011) Mol Cell Pharmacol , vol.3 , pp. 83-92
    • Shukla, G.C.1    Singh, J.2    Barik, S.3
  • 50
    • 34748853883 scopus 로고    scopus 로고
    • A simple array platform for microRNA analysis and its application in mouse tissues
    • Tang X, Gal J, Zhuang X, Wang W, Zhu H, Tang G. 2007; A simple array platform for microRNA analysis and its application in mouse tissues. RNA 13: 1803–1822.
    • (2007) RNA , vol.13 , pp. 1803-1822
    • Tang, X.1    Gal, J.2    Zhuang, X.3    Wang, W.4    Zhu, H.5    Tang, G.6
  • 51
    • 58249107416 scopus 로고    scopus 로고
    • Identification of glucose-regulated miRNAs from pancreatic {beta} cells reveals a role for miR-30d in insulin transcription
    • Tang X, Muniappan L, Tang G, Ozcan S. 2009; Identification of glucose-regulated miRNAs from pancreatic {beta} cells reveals a role for miR-30d in insulin transcription. RNA 15: 287–293.
    • (2009) RNA , vol.15 , pp. 287-293
    • Tang, X.1    Muniappan, L.2    Tang, G.3    Ozcan, S.4
  • 52
    • 0141643297 scopus 로고    scopus 로고
    • Nestin-lineage cells contribute to the microvasculature but not endocrine cells of the islet
    • Treutelaar MK, Skidmore JM, Dias-Leme CL et al. 2003; Nestin-lineage cells contribute to the microvasculature but not endocrine cells of the islet. Diabetes 52: 2503–2512.
    • (2003) Diabetes , vol.52 , pp. 2503-2512
    • Treutelaar, M.K.1    Skidmore, J.M.2    Dias-Leme, C.L.3
  • 53
    • 0020679246 scopus 로고
    • Effect of poly(ADP-ribose) synthetase inhibitor administration to rats before and after injection of alloxan and streptozotocin on islet proinsulin synthesis
    • Uchigata Y, Yamamoto H, Nagai H, Okamoto H. 1983; Effect of poly(ADP-ribose) synthetase inhibitor administration to rats before and after injection of alloxan and streptozotocin on islet proinsulin synthesis. Diabetes 32: 316–318.
    • (1983) Diabetes , vol.32 , pp. 316-318
    • Uchigata, Y.1    Yamamoto, H.2    Nagai, H.3    Okamoto, H.4
  • 54
    • 84908573062 scopus 로고    scopus 로고
    • Improved differentiation of umbilical cord blood-derived mesenchymal stem cells into insulin-producing cells by PDX-1 mRNA transfection
    • Van Pham P, Thi-My Nguyen P, Thai-Quynh Nguyen A et al. 2014; Improved differentiation of umbilical cord blood-derived mesenchymal stem cells into insulin-producing cells by PDX-1 mRNA transfection. Differentiation 87: 200–208.
    • (2014) Differentiation , vol.87 , pp. 200-208
    • Van Pham, P.1    Thi-My Nguyen, P.2    Thai-Quynh Nguyen, A.3
  • 55
    • 84942195926 scopus 로고    scopus 로고
    • Reduced silent information regulator 1 signaling exacerbates myocardial ischemia-reperfusion injury in type 2 diabetic rats and the protective effect of melatonin
    • Yu L, Liang H, Dong X et al. 2015; Reduced silent information regulator 1 signaling exacerbates myocardial ischemia-reperfusion injury in type 2 diabetic rats and the protective effect of melatonin. J Pineal Res 59: 376–390.
    • (2015) J Pineal Res , vol.59 , pp. 376-390
    • Yu, L.1    Liang, H.2    Dong, X.3
  • 56
    • 33845234231 scopus 로고    scopus 로고
    • Stem cells with potential to generate insulin producing cells in man
    • Zulewski H. 2006; Stem cells with potential to generate insulin producing cells in man. Swiss Med Wkly 136: 647–654.
    • (2006) Swiss Med Wkly , vol.136 , pp. 647-654
    • Zulewski, H.1
  • 57
    • 0035119871 scopus 로고    scopus 로고
    • Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes
    • Zulewski H, Abraham EJ, Gerlach MJ et al. 2001; Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. Diabetes 50: 521–533.
    • (2001) Diabetes , vol.50 , pp. 521-533
    • Zulewski, H.1    Abraham, E.J.2    Gerlach, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.