Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway

Scientific Reports

Volumn 7, Issue , 2017, Pages

  Fang, Evandro F ^a   Waltz, Tyler B ^a   Kassahun, Henok ^a,b   Lu, Qiping ^a   Kerr, Jesse S ^a   Morevati, Marya ^a,c   Fivenson, Elayne M ^a   Wollman, Bradley N ^a   Marosi, Krisztina ^a   Wilson, Mark A ^a   Iser, Wendy B ^a   Mark Eckley, D ^a   Zhang, Yongqing ^a   Lehrmann, Elin ^a   Goldberg, Ilya G ^a   Scheibye Knudsen, Morten ^a,c   Mattson, Mark P ^a   Nilsen, Hilde ^b   Bohr, Vilhelm A ^a,c   Becker, Kevin G ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b AKERSHUS UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; DNA BINDING PROTEIN; REACTIVE OXYGEN METABOLITE; SKN-1 PROTEIN, C ELEGANS; TOMATIDINE; TOMATINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTOME;

ANALOGS AND DERIVATIVES; ANIMAL; CAENORHABDITIS ELEGANS; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; LONGEVITY; METABOLISM; MITOCHONDRION; MITOPHAGY; MUSCLE; ORGANELLE BIOGENESIS; PHYSIOLOGICAL STRESS; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; LONGEVITY; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; MUSCLES; NF-E2-RELATED FACTOR 2; ORGANELLE BIOGENESIS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TOMATINE; TRANSCRIPTION FACTORS; TRANSCRIPTOME;

EID: 85017389943     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep46208     Document Type: Article

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