Asymmetric positioning of Cas1-2 complex and Integration Host Factor induced DNA bending guide the unidirectional homing of protospacer in CRISPR-Cas type I-E system

Nucleic Acids Research

Volumn 45, Issue 1, 2017, Pages 367-381

  Yoganand, K N R ^a   Sivathanu, R ^a   Nimkar, Siddharth ^a   Anand, B ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY GUWAHATI   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CAS1-2 COMPLEX; CRISPR ASSOCIATED PROTEIN; HYBRID PROTEIN; INTEGRATION HOST FACTOR; UNCLASSIFIED DRUG; BACTERIAL DNA; CAS2 PROTEIN, E COLI; DEOXYRIBONUCLEASE; ENDONUCLEASE; ESCHERICHIA COLI PROTEIN; PROTEIN BINDING; SIGNAL PEPTIDE; YGBT PROTEIN, E COLI;

ARTICLE; BINDING SITE; CONTROLLED STUDY; CRISPR CAS SYSTEM; DNA STRUCTURE; ESCHERICHIA COLI; GENETIC ANALYSIS; IMMUNOPRECIPITATION; LEADER REPEAT JUNCTION; NONHUMAN; PROTEIN BINDING; PROTEIN LOCALIZATION; CHEMISTRY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONFORMATION; GENETICS; IMMUNOLOGY; NUCLEOTIDE SEQUENCE; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE;

BASE SEQUENCE; BINDING SITES; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; DNA, BACTERIAL; ENDODEOXYRIBONUCLEASES; ENDONUCLEASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; INTEGRATION HOST FACTORS; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, SECONDARY;

EID: 85016160582     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkw1151     Document Type: Article

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