CRISPR Immunological Memory Requires a Host Factor for Specificity

Molecular Cell

Volumn 62, Issue 6, 2016, Pages 824-833

  Nuñez, James K ^a   Bai, Lawrence ^b   Harrington, Lucas B ^a   Hinder, Tracey L ^a   Doudna, Jennifer A ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAS1 PROTEIN; CAS2 PROTEIN; CRISPR ASSOCIATED PROTEIN; CURVED DNA; HOST FACTOR; HYDROXYL RADICAL; INTEGRASE; INTEGRATION HOST FACTOR; INTEGRATION HOST FACTOR ALPHA; INTEGRATION HOST FACTOR BETA; SIGNAL PEPTIDE; UNCLASSIFIED DRUG; BACTERIAL DNA; CAS2 PROTEIN, E COLI; DEOXYRIBONUCLEASE; ENDONUCLEASE; ESCHERICHIA COLI PROTEIN; INTEGRATION HOST FACTOR, E COLI; PROTEIN BINDING; YGBT PROTEIN, E COLI;

ARTICLE; BACTERIAL GROWTH; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CRISPR CAS SYSTEM; ESCHERICHIA COLI; GEL MOBILITY SHIFT ASSAY; HIGH THROUGHPUT SEQUENCING; IMMUNOLOGICAL MEMORY; NUCLEOTIDE SEQUENCE; PROTEIN FOOTPRINTING; ADAPTIVE IMMUNITY; BINDING SITE; CHEMISTRY; CONFORMATION; GENETICS; IMMUNOLOGY; METABOLISM; STRUCTURE ACTIVITY RELATION; TIME FACTOR;

ADAPTIVE IMMUNITY; BINDING SITES; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; DNA, BACTERIAL; ENDODEOXYRIBONUCLEASES; ENDONUCLEASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; IMMUNOLOGIC MEMORY; INTEGRATION HOST FACTORS; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

EID: 84974693401     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.04.027     Document Type: Article

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